A complex immunomodulatory composition containing inonotus obliquus and various fungal polysaccharides, and optionally colostrum, and a preparation method thereof

Abstract

The application discloses a kind of containing inositol chaga polycell polysaccharide complex immunomodulation composition and preparation method thereof.The present formula is included inositol chaga fungus conditioning system, match pine mushroom, grifola etc seven kinds of fungal polysaccharide free combination, while selectively adding cow and sheep colostrum and complex probiotics, form anti-inflammatory clear inflammation, mucosa repair, passive immunity supplement, intestinal flora regulation four-in-one synergistic compatibility system.The present application is open formula structure, can flexibly increase and reduce inositol chaga, colostrum and other raw materials, build multi-level differentiation product matrix.The whole production process uses low-temperature process, maximumly retains various active ingredients, is suitable for allergic constitution, chronic sinusitis, recurrent otitis media, immunocompromised population conditioning, formula expansion is strong, protection range is wide, is suitable for brand long-term layout and industrialized batch production.

Description

[0001] This invention belongs to the field of functional health foods and nutritional formulation technology. Specifically, it relates to a multi-fungal fungal polysaccharide formulation with freely selectable ingredients, inoculum birch incorporated into the immune system, optional addition of colostrum, and a multi-synergistic, multi-open-base probiotic formulation. This can lead to dozens of products, including milk powder, solid beverages, dietary powders, and other functional foods. Background Technology

[0002] Chaga mushroom polysaccharides differ from ordinary fungal polysaccharides. Besides regulating immunity, they can reduce chronic inflammation, improve allergic constitutions, regulate sugar metabolism, and alleviate recurrent upper respiratory tract inflammation, making them the highest quality fungal raw material for treating sensitive constitutions. Matsutake mushroom polysaccharides, Hericium erinaceus polysaccharides, Grifola frondosa polysaccharides, Ganoderma lucidum polysaccharides, Trametes versicolor polysaccharides, and Lentinus edodes polysaccharides each have their own regulatory focuses. Combined with Chaga mushroom, they can achieve a dual effect of anti-inflammation and immunity: bovine colostrum and sheep colostrum supplement passive immunoglobulins, and probiotics establish themselves in the gut to build an immune foundation. Currently, all formulas on the market have significant shortcomings: they do not integrate Chaga mushroom and the six traditional fungal polysaccharides into a single formula system, preventing flexible combinations; formulas are all fixed, preventing the arbitrary selection of Chaga mushroom, and the creation of regular and enhanced anti-allergy versions; they lack the integrated logic of mucosal repair, anti-inflammation, passive immunity, and gut regulation, simply mixing raw materials; high-temperature production destroys the activity of Chaga mushroom, colostrum IgG, and probiotics; one formula can only make one product, making it impossible to build a complete product matrix. This invention incorporates Inonotus obliquus into the overall protective framework, creating a selectable formula that can be added or subtracted. Summary of the Invention

[0003] The purpose of this invention is to overcome the shortcomings of existing technologies, such as fixed formulations, easy loss of activity, lack of synergistic compatibility, and limited product expansion. It provides an open-ended master formula system that allows for easy replacement of bacterial species, adjustment of raw material selection, change of carrier, and adjustment of concentration to derive multiple products. Simultaneously, multiple bacterial polysaccharides, colostrum, and probiotics create a synergistic effect, and the production process retains all biological activity to the greatest extent. A compound immune-regulating composition includes a main carrier, a fungal polysaccharide component, and a functional compound component. The fungal polysaccharide component is any combination of: Inonotus obliquus, Matsutake mushroom polysaccharide, Hericium erinaceus polysaccharide, Grifola frondosa polysaccharide, Ganoderma lucidum polysaccharide, Trametes versicolor polysaccharide, and Lentinus edodes polysaccharide. The functional compound component includes: prebiotics, compound probiotics, vitamins, minerals, and colostrum immune-active extract. The colostrum immune-active extract is one or more of bovine colostrum powder, sheep colostrum powder, and immunoglobulin IgG. The raw materials are proportioned by weight as follows: main carrier 50-95 parts, fungal polysaccharide component 0.1-8 parts, and functional compound component 0.05-8 parts. The main ingredient carrier is selected from one or more of the following: goat milk powder, cow milk powder, camel milk powder, cereal powder, maltodextrin, and fruit and vegetable powder. Prebiotics include oligosaccharides, galactooligosaccharides, inulin, and water-soluble dietary fiber. The compound probiotic contains at least two strains: Bifidobacterium, Lactobacillus rhamnosus, and Lactobacillus acidophilus. The combination can be processed into milk powder, solid beverages, instant powders, and dietary supplements.

[0004] This invention has four core innovations: 1. The formula adds Inonotus obliquus, forming two systems: general immunity and chronic anti-inflammatory, specifically targeting allergic rhinitis, sinusitis, otitis media, and those with a perennially inflammatory constitution. This is the core innovation that distinguishes it from all other formulas. 2. All fungi are optional additives. They can be used alone or in combination with matsutake polysaccharides and maitake mushroom polysaccharides. The product can be divided into basic, anti-allergy, and metabolic conditioning versions. 3. Quadruple Synergy: Inonotus obliquus clears inflammation from chronic diseases + fungal polysaccharides repair mucous membranes + colostrum replenishes antibodies + prebiotics stabilize immunity. This unique effect comes from the combination of ingredients, which is not something that current technology can easily conceive of. 4. Open structure: Ordinary products can omit the addition of Inonotus obliquus and colostrum; high-end anti-allergy products can add both, with one patent protecting the entire product line.

[0005] The compound probiotic contains at least two strains of Bifidobacterium, Lactobacillus rhamnosus, and Lactobacillus acidophilus.

[0006] The composition can be processed into modified milk powder, solid beverage, dietary powder, and functional nutritional powder.

[0007] This invention possesses four core innovative advantages: 1. This invention adds a Chaga mushroom polysaccharide component to construct a dual-regulatory system that combines general immune regulation and chronic inflammation clearance, targeting... It effectively improves allergic rhinitis, chronic sinusitis, recurrent otitis media, and conditions prone to inflammation, unlike traditional single-fungal treatments. Sugar recipe.

[0008] 2. All fungal components of this invention can be freely selected and combined. Single fungal polysaccharides can be used alone, or multiple fungi can be combined. The components can be flexibly separated. The product line includes several categories such as basic nutrition, anti-inflammatory and anti-allergy, and metabolic regulation.

[0009] 3. This invention forms a four-fold synergistic regulatory mechanism: Inonotus obliquus clears chronic inflammation in the body, and various fungal polysaccharides repair the mucosal tissue. The combination of tissue and colostrum replenishes passive immune antibodies, while probiotics strengthen the intestinal immune barrier. This synergistic effect is not achieved by existing conventional raw materials. Combinations can achieve this.

[0010] 4. This invention employs an open-ended formulation structure, allowing for the selective omission of Inonotus obliquus and colostrum in the preparation of ordinary basic products, or it can be used entirely... The company adds ingredients to prepare high-end anti-allergy and immune products, with one formula covering the entire product matrix to meet diverse production needs. Detailed Implementation

[0011] The technical solution of the present invention will be described in detail below through specific embodiments, but this does not limit the scope of protection of the present invention.

[0012] Example 1: Basic Nutritional Conditioning Formula for Children (No Chaga Mushrooms, No Colostrum) By weight: 88 parts goat milk powder, 1.2 parts matsutake polysaccharide, 2.5 parts prebiotics, 0.3 parts probiotics, and multivitamins and minerals. 1.0 copy.

[0013] Preparation process: Raw materials are sieved through an 80-100 mesh fine sieve, and then subjected to a temperature gradient mixing process in a sterile environment, followed by low-speed homogenization. The product is processed using low-temperature pasteurization, low-temperature spray drying below 70℃, aseptic filling, inspection, and warehousing.

[0014] Example 2: Enhanced Respiratory Allergy Relief Formula for Children (Contains Inonotus obliquus and Bovine Colostrum) By weight: 85 parts goat milk powder, 1 part matsutake polysaccharide, 0.9 parts birch polysaccharide, 2 parts bovine colostrum powder, prebiotics 2.3 servings, 0.3 servings of probiotics, and 0.8 servings of multivitamins and minerals.

[0015] The preparation process is the same as in Example 1.

[0016] Example 3: Spleen and Stomach Nourishing and Conditioning Formula (Hericium erinaceus + Matsutake Mushroom Combination) By weight: 85 parts composite carrier, 1.5 parts Hericium erinaceus polysaccharide, 0.8 parts Matsutake polysaccharide, 3 parts inulin, 0.25 parts probiotics. 0.8 parts of trace elements.

[0017] The preparation process is the same as in Example 1.

[0018] Example 4: Adult Anti-inflammatory and Metabolic All-in-One Formula (Multi-bacterial Complex + Sheep Colostrum) By weight: 80 parts basic powder, 3.5 parts complex polysaccharide of Grifola frondosa, Ganoderma lucidum, and Inonotus obliquus, and sheep colostrum powder. 1.8 servings, 4 servings of prebiotics, 0.4 servings of probiotics, and 1.2 servings of multivitamins and minerals.

[0019] The preparation process is the same as in Example 1.

[0020] Preparation method The preparation method of any of the above-mentioned composite immunomodulatory compositions of the present invention includes the following steps: (1) Raw material sieving: All raw materials are sieved through an 80-100 mesh screen to remove lumps and impurities and ensure uniform powder. exquisite; (2) Gradient mixing: Gradient feeding and layered mixing are carried out in a sterile environment at room temperature to avoid the mixing of probiotics and active proteins. Inactivation upon heating; (3) Homogenization and dispersion: low-speed homogenization and stirring to ensure uniform distribution of fungal polysaccharides, colostrum active ingredients, probiotics and trace elements; (4) Low-temperature sterilization: The pasteurization process is used instead of high-temperature sterilization to preserve biological activity; (5) Low-temperature drying: The processing temperature does not exceed 75℃ throughout the process to maximize the preservation of Inonotus obliquus polysaccharides, various fungal polysaccharides, Colostrum immunoglobulin and probiotic activity; (6) Aseptic filling: After drying, the product is sealed and aseptically filled in a clean environment, and stored in the warehouse after passing quality inspection.

Claims

1. A compound immunomodulatory composition containing Inonotus obliquus and various fungal polysaccharides, optionally combined with colostrum, and its preparation method.

2. A complex immunomodulatory composition containing multiple fungal polysaccharides, characterized in that, The product comprises a main carrier, fungal polysaccharide components, and functional compound components. The fungal polysaccharides are one or more of the following: Inonotus obliquus polysaccharide, Matsutake polysaccharide, Hericium erinaceus polysaccharide, Grifola frondosa polysaccharide, Ganoderma lucidum polysaccharide, Trametes versicolor polysaccharide, and Lentinus edodes polysaccharide. The functional compound components include prebiotics, compound probiotics, vitamins, minerals, and colostrum immune-active extracts. The colostrum immune-active extracts are any one or more of the following: bovine colostrum powder, sheep colostrum powder, and immunoglobulins. The weight parts of each raw material are: main carrier 50-95 parts, fungal polysaccharide components 0.1-8 parts, and functional compound components 0.05-8 parts.

3. The composition according to claim 1, characterized in that: The main carrier is any one or more of the following: goat milk powder, cow milk powder, camel milk powder, grain powder, maltodextrin, and fruit and vegetable powder.

4. The composition according to claim 1, characterized in that: All fungal polysaccharides were prepared using a low-temperature water extraction process, and the effective purity of the polysaccharides was ≥20%.

5. The composition according to claim 1, characterized in that: The prebiotics are selected from one or more of fructooligosaccharides, galactooligosaccharides, inulin, and water-soluble dietary fiber.

6. The composition according to claim 1, characterized in that: The compound probiotic contains at least two strains of Bifidobacterium, Lactobacillus rhamnosus, and Lactobacillus acidophilus.

7. The composition according to claim 1, characterized in that: Colostrum is produced by low-temperature spray drying, which fully preserves the activity of IgG immunoglobulins.

8. The composition according to claim 1, characterized in that: When used in combination with Inonotus obliquus polysaccharide and matsutake polysaccharide, they synergistically reduce chronic respiratory inflammation and allergic reactions.

9. The composition according to claim 1, characterized in that: This composition can be processed into various dosage forms such as modified milk powder, solid beverage, dietary powder, and functional nutritional powder.

10. The composition according to claim 1, characterized in that: The formula can optionally include or omit Inonotus obliquus polysaccharide, making it suitable for both regular nutritional and anti-allergy-enhanced versions.

11. The composition according to claim 1, characterized in that: The formula can be optionally supplemented with colostrum. The basic version does not contain colostrum, while the version with colostrum is a premium immune-boosting version.

12. A method for preparing the composition according to any one of claims 1 to 10, characterized in that... The steps are as follows: raw material screening, ambient temperature gradient mixing, homogenization and dispersion, low-temperature pasteurization, low-temperature spray drying, and aseptic packaging; the maximum temperature of all production processes does not exceed 75℃, so as to preserve the biological activity of Inonotus obliquus, various fungal polysaccharides, probiotics and colostrum.