Application of whole plant dry powder of pteroxygonum giraldii to preparation of sow feed additive and application method

Abstract

The application discloses application and application method of whole-plant dry powder of Pterygium of Cephalotaxus fortunei in preparation of sow feed additives, and provides a new application of the whole-plant dry powder of Pterygium of Cephalotaxus fortunei as a sow feed additive. The feed additive can improve the lactation performance of sows, promote the average daily milk yield of sows, has the lactation promotion effect on sows, can promote the immunoglobulin content of colostrum of sows to increase, has the immunization strengthening effect on colostrum of sows, can improve the colostrum quality of sows, can improve the growth performance of offspring piglets, and is suitable for continuous feeding of sows from mating to weaning.

Description

Technical Field

[0001] This invention relates to the field of pig feed products technology, specifically to the application and application method of whole plant dry powder of *Capsella bursa-pastoris* in the preparation of feed additives for sows. Background Technology

[0002] Sow's milk is a crucial source of nutrition for the survival and growth of newborn piglets. Maternal immunoglobulins cannot be passed to the fetus via the placenta, and piglets are born with immature humoral immunity and intestinal function. Therefore, colostrum secreted by the sow is an important source of exogenous nutrition for piglets to acquire passive immunity, replenish initial energy, and drive intestinal development. The sow's lactation performance, such as milk yield, immunoglobulin content, and colostrum quality, significantly impacts the piglets' reproductive performance, directly affecting the production returns of offspring.

[0003] If the lactation performance of sows can be regulated and improved by feeding them suitable feed products, there will be great economic benefits. Therefore, it is very necessary to develop feed products that can improve the lactation performance of sows. Summary of the Invention

[0004] The purpose of this invention is to provide the application and method of whole plant powder of *Capsella bursa-pastoris* in the preparation of sow feed additives. This invention provides a new application of whole plant powder of *Capsella bursa-pastoris* as a sow feed additive. By feeding sows the feed additive described in this invention, the lactation performance of sows can be improved. The sow feed additive of this invention can promote the increase of the average daily milk production of sows, has a lactation-promoting effect, can promote the increase of the immunoglobulin content of sow colostrum, has a colostrum-enhancing effect, can improve the quality of sow colostrum, and can improve the growth performance of offspring piglets. It is suitable for continuous feeding of sows throughout the entire breeding cycle from mating to weaning.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] Application of whole plant powder of *Capsella bursa-pastoris* in the preparation of feed additives that can improve the average daily milk production of sows, increase the immunoglobulin content of sow colostrum, improve the quality of sow colostrum, and enhance the growth performance of offspring piglets.

[0007] Preferably, increasing the immunoglobulin content of sow colostrum means increasing the content of at least one of IgG, IgA, and IgM in sow colostrum.

[0008] Preferably, the content of at least one of milk fat, non-fat solids, milk protein and lactose in sow colostrum is increased.

[0009] Preferably, improving the growth performance of offspring piglets means: improving at least one of the following: birth weight, weaning litter weight, litter weight gain, and average daily weight gain of offspring piglets.

[0010] Preferably, the preparation method of the whole plant powder of *Capsella bursa-pastoris* includes the following steps: selecting, washing, draining, drying and pulverizing fresh whole plant of *Capsella bursa-pastoris* to obtain whole plant powder of *Capsella bursa-pastoris*.

[0011] The term "whole plant of *Cephalotaxus fortunei*" refers to the entire plant, including both the above-ground parts (stems, leaves, and flowers) and the underground parts (roots). When harvesting fresh *Cephalotaxus fortunei*, the roots, stems, leaves, and flowers are harvested together.

[0012] Preferably, the drying temperature for drying the whole plant of *Cephalotaxus fortunei* is 45°C.

[0013] Preferably, when drying the whole plant of *Capsella bursa-pastoris*, the moisture content of the dried whole plant is 11.8%.

[0014] Preferably, when pulverizing the whole plant of *Capsella bursa-pastoris*, the whole plant is pulverized until it passes through an 80-mesh standard sieve.

[0015] Preferably, the total selenium content in the whole plant dry powder of the prepared *Cephalotaxus fortunei* is 805.9 mg / kg.

[0016] Preferably, the organic selenium accounts for 85.8% of the total selenium mass in the prepared whole plant dry powder of *Cephalotaxus fortunei*.

[0017] Preferably, the whole plant dry powder of *Corydalis oryzae* is the whole plant dry powder of *Corydalis oryzae*.

[0018] Preferably, the amount of the whole plant dry powder of *Capsella bursa-pastoris* added to the sow's daily diet is 0.05%.

[0019] The application method of the above technical solution is as follows: feed the sow the whole plant dry powder of the broken rice shepherd's purse from the day of mating to the 21st day of lactation.

[0020] Specifically, for example: 0.05 kg of the whole plant powder of *Capsella bursa-pastoris* described in this invention is added to 100 kg of sow diet (complete diet). The mixed feed obtained by thoroughly mixing the whole plant powder of *Capsella bursa-pastoris* described in this invention with the sow diet is fed to the sow. The sow diet can be a commercially available sow diet or a sow diet formulated to meet the nutritional needs of the feeding stage. Moreover, the sow is fed the above-mentioned mixed feed containing the whole plant powder of *Capsella bursa-pastoris* described in this invention from at least the day of mating until the 21st day of lactation.

[0021] The present invention also provides a sow feed additive containing the whole plant dry powder of *Capsella bursa-pastoris* as described in the above technical solution, wherein the whole plant dry powder of *Capsella bursa-pastoris* is the only active ingredient in the sow feed additive.

[0022] The present invention also provides a sow feed, wherein the sow feed comprises the sow feed additives described in the above technical solution.

[0023] For example, the sow feed obtained by uniformly mixing the whole plant powder of *Capsella bursa-pastoris* described in this invention with a sow diet (complete diet) has the whole plant powder of *Capsella bursa-pastoris* added at an amount of 0.05% in the sow diet. In the prepared sow feed, the whole plant powder of *Capsella bursa-pastoris* is the sole active ingredient, achieving the technical effect of this invention.

[0024] The beneficial effects of this invention are as follows: The sow feed additive of this invention can promote an increase in the average daily milk production of sows, thus promoting lactation; it can increase the immunoglobulin content in sow colostrum, thus enhancing sow colostrum immunity; it can improve the quality of sow colostrum; it can improve the growth performance of offspring piglets; it is suitable for continuous feeding to sows throughout the entire breeding to weaning cycle; and it has good safety and feasibility for large-scale application. Compared to a high addition level of 0.10%, the sow feed additive of this invention exhibits superior overall effects at a low addition level of 0.05%, and its application effects cannot be replaced by conventional selenium-based feed products with the same addition level. Detailed Implementation

[0025] The following are specific embodiments of the present invention, which further describe the technical solution of the present invention. However, the scope of protection of the present invention is not limited to these embodiments. All changes or equivalent substitutions that do not depart from the concept of the present invention are included within the scope of protection of the present invention.

[0026] Example 1

[0027] The preparation method of whole plant dry powder of *Capsella bursa-pastoris* includes the following steps: selecting, washing, draining, drying and pulverizing fresh whole plant of *Capsella bursa-pastoris* to obtain whole plant dry powder of *Capsella bursa-pastoris*, which is the sow feed additive of the present invention.

[0028] The process involves selecting and processing freshly harvested whole plants of *Capsella bursa-pastoris* to remove impurities, rotten stems and leaves, and other undesirable materials. The plants are then washed with clean water to remove mud and debris, drained, and then subjected to low-temperature drying to reduce their moisture content. Finally, the dried plants are pulverized to obtain dry powder, which is the sow feed additive of this invention.

[0029] The term "whole plant of *Cephalotaxus fortunei*" refers to the entire plant, including both the above-ground parts (such as stems, leaves, and flowers) and the underground parts (such as roots). When harvesting fresh *Cephalotaxus fortunei*, the roots, stems, leaves, and flowers are harvested together.

[0030] When drying the whole plant of *Cephalotaxus fortunei*, the drying temperature is 45℃.

[0031] When drying the whole plant of *Capsella bursa-pastoris*, the moisture content of the dried whole plant is 11.8%.

[0032] When pulverizing the whole plant of *Hydrocotyle sibthorpioides*, pulverize the whole plant until it passes through an 80-mesh standard sieve.

[0033] The total selenium content in the whole plant dry powder of the prepared *Cephalotaxus fortunei* was 805.9 mg / kg.

[0034] The analysis showed that organic selenium accounted for 85.8% of the total selenium mass in the whole plant dry powder of *Capsella bursa-pastoris* obtained from the test.

[0035] The whole plant powder of *Corydalis oryzae* is the whole plant powder of *Corydalis oryzae*.

[0036] Example 2

[0037] Sixty healthy Landrace × Large White crossbred sows of similar parity (2nd-3rd parity), weighing 180-220 kg, with backfat thickness of 16-18 mm, were selected. All sows were randomly divided into three treatment groups on the same breeding day: a control group, experimental group 1, and experimental group 2, with 20 sows in each group, housed in individual pens. All sows were bred according to the farm's standard breeding procedures, with consistent personnel, insemination tube type, and semen source throughout the process to ensure complete consistency in breeding procedures across all groups and eliminate human and equipment errors. The experiment officially began on the day of breeding, designated as day 0 of the experiment.

[0038] During the trial, the basal diet, feeding environment, and daily management conditions of all groups of sows remained completely consistent, with free access to feed and water throughout the entire period. The feeding pens were uniformly changed in stages: from mating to 30 days of gestation, sows were kept in gestation pens; from 30 to 90 days of gestation, they were moved to semi-gestation pens; and after 90 days of gestation, they were moved to elevated farrowing pens in the farrowing house, with single-pen feeding throughout the entire period.

[0039] All groups adopted a uniform "high-low-high" phased feeding program for pregnant sows: 1.8-2.2 kg / day post-mating (days 1-28), 2.0-2.5 kg / day during days 29-90 of gestation, and 3.0-3.5 kg / day during days 91-114 of gestation. The same batch of basal diet was fed throughout the experiment, with a metabolizable energy of 13.8 MJ / kg and a crude protein content of 16.5%. Daily feeding and management practices, including water, lighting, and disinfection, were implemented synchronously across all groups. All groups underwent the same mating treatment concurrently.

[0040] No additional yeast selenium, sodium selenite, nano selenium, 2-hydroxy-4-methylselenobutyric acid, or hormone-based galactagogues were added to any group for experimental purposes.

[0041] The feeds given to the sows in each treatment group were as follows:

[0042] Control group: basal diet.

[0043] Experimental Group 1: 0.05% of the pig feed additive prepared in Example 1 of this invention was added to the basal diet and mixed evenly to prepare feed for the sows in Experimental Group 1.

[0044] Experimental Group 2: 0.10% of the pig feed additive prepared in Example 1 of this invention was added to the basal diet and mixed evenly to prepare feed for the sows in Experimental Group 2.

[0045] The selenium content in the feed for sows prepared in experimental groups 1 and 2 was <0.5 mg / kg.

[0046] The feeding cycle begins on the day of mating and ends on the 21st day of lactation.

[0047] In each group, approximately 20 mL of mixed colostrum samples from the front, middle, and hind teats of the sows were collected within 0-6 hours postpartum (before the piglets suckled). The levels of immunoglobulins IgG, IgA, and IgM in the colostrum of each group were measured, as were the milk fat, non-fat solids, milk protein, and lactose content in the colostrum of each group.

[0048] Milk production in each group was collected and measured from day 1 of lactation to day 21 of lactation, and the average daily milk production was calculated.

[0049] The growth performance of piglets born to sows in each group was measured.

[0050] The test results are shown in Table 1-6.

[0051] Table 1. Effects of different treatments on average daily milk yield of sows

[0052]

[0053] Data in the table are expressed as mean. Different lowercase letters in the same row indicate significant differences (P<0.05).

[0054] As shown in Table 1, compared with the control group, the average daily milk production of sows in both experimental groups 1 and 2 was significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of average daily milk production of sows and has a lactation-promoting effect. Furthermore, compared with the control group, the average daily milk production of experimental group 1 increased by 23.54%, and the average daily milk production of experimental group 2 increased by 19.21%. Experimental group 1 has a higher potential to promote the increase of average daily milk production of sows than experimental group 2, indicating that in terms of improving the average daily milk production of sows, experimental group 1 with a low addition of 0.05% has a greater technical effect and industrial application advantage than experimental group 2 with a high addition of 0.10%. This shows that the low addition of 0.05% has a better effect window in promoting the increase of average daily milk production of sows. At the same time, it also shows that the technical effect of the sow feed additive of the present invention in promoting the increase of average daily milk production of sows is not linearly enhanced with the increase of the addition amount of the present invention.

[0055] Table 2. Effects of different treatments on the immunoglobulin content in sow colostrum.

[0056]

[0057] Data in the table are expressed as mean. Different lowercase letters in the same row indicate significant differences (P<0.05).

[0058] As shown in Table 2, compared with the control group, the contents of IgG, IgA and IgM in the colostrum of experimental group 1 and experimental group 2 were significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of the contents of immunoglobulins IgG, IgA and IgM in sow colostrum and has the effect of enhancing the immunity of sow colostrum.

[0059] Furthermore, compared to the control group, the IgG content in experimental group 1 increased by 29.07%, and the IgG content in experimental group 2 increased by 18.38%. Experimental group 1 has a higher potential to promote the increase of sow colostrum immunoglobulin IgG content than experimental group 2. This indicates that in terms of increasing sow colostrum immunoglobulin IgG content, experimental group 1 with a low addition amount of 0.05% has a greater technical effect and industrial application advantage than experimental group 2 with a high addition amount of 0.10%. This shows that the low addition amount of 0.05% has a better effect window in promoting the increase of sow colostrum immunoglobulin IgG content. At the same time, it also shows that the technical effect of the sow feed additive of the present invention in promoting the increase of sow colostrum immunoglobulin IgG content is not linearly enhanced with the increase of the addition amount of the present invention.

[0060] Furthermore, compared to the control group, the IgA content in experimental group 1 increased by 15.80%, and the IgA content in experimental group 2 increased by 11.80%. Experimental group 1 has a higher potential to promote the increase of immunoglobulin IgA content in sow colostrum compared to experimental group 2. This indicates that in terms of increasing the immunoglobulin IgA content in sow colostrum, experimental group 1 with a low addition amount of 0.05% has a greater technical effect and industrial application advantage than experimental group 2 with a high addition amount of 0.10%. This shows that the low addition amount of 0.05% has a better effect window in promoting the increase of immunoglobulin IgA content in sow colostrum. At the same time, it also shows that the technical effect of the sow feed additive of the present invention in promoting the increase of immunoglobulin IgA content in sow colostrum is not linearly enhanced with the increase of the addition amount of the present invention.

[0061] Furthermore, compared to the control group, the IgM content in experimental group 1 increased by 45.43%, and the IgM content in experimental group 2 increased by 33.02%. Experimental group 1 has a higher potential to promote the increase of sow colostrum immunoglobulin IgM content than experimental group 2. This indicates that in terms of increasing sow colostrum immunoglobulin IgM content, experimental group 1 with a low addition amount of 0.05% has a greater technical effect and industrial application advantage than experimental group 2 with a high addition amount of 0.10%. This shows that the low addition amount of 0.05% has a better effect window in promoting the increase of sow colostrum immunoglobulin IgM content. At the same time, it also shows that the technical effect of the sow feed additive of the present invention in promoting the increase of sow colostrum immunoglobulin IgM content is not linearly enhanced with the increase of the addition amount of the present invention.

[0062] Table 3. Effects of different treatments on the quality of colostrum in sows

[0063]

[0064] Data in the table are expressed as mean. Different lowercase letters in the same row indicate significant differences (P<0.05).

[0065] As shown in Table 3, compared with the control group, the colostrum fat content of experimental group 1 was significantly increased (P<0.05), while the difference in experimental group 2 was not significant; compared with experimental group 1, the colostrum fat content of experimental group 2 was not significantly different, but showed a decreasing trend; indicating that the application of the sow feed additive of the present invention at a low addition amount of 0.05% can promote the increase of colostrum fat content in sows.

[0066] Compared with the control group, the non-fat solids content of colostrum in both experimental groups 1 and 2 was significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of non-fat solids content in sow colostrum. Furthermore, compared with the control group, the non-fat solids content of colostrum in sows in experimental group 1 increased by 19.57%, and the non-fat solids content of colostrum in sows in experimental group 2 increased by 15.55%. Experimental group 1 has a higher potential to promote the increase of non-fat solids content in sow colostrum compared with experimental group 2.

[0067] Compared with the control group, the colostrum protein content of both experimental groups 1 and 2 was significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of colostrum protein content in sows. Furthermore, compared with the control group, the colostrum protein content of sows in experimental group 1 increased by 18.37%, and the colostrum protein content of sows in experimental group 2 increased by 14.86%, indicating that experimental group 1 has a higher potential to promote the increase of colostrum protein content in sows than experimental group 2.

[0068] Compared with the control group, the colostrum lactose content in both experimental groups 1 and 2 was significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of colostrum lactose content in sows. Furthermore, compared with the control group, the colostrum lactose content in experimental group 1 increased by 19.68%, and the colostrum lactose content in experimental group 2 increased by 16.48%, indicating that experimental group 1 has a higher potential to promote the increase of colostrum lactose content in sows than experimental group 2.

[0069] The above indicates that applying the sow feed additive of the present invention at a low addition level of 0.05% can promote the increase of milk fat, non-fat solids, milk protein, and lactose content in sow colostrum, thus improving the quality of sow colostrum. Furthermore, the experimental group 1 with a low addition level of 0.05% has a greater technical and industrial application advantage than the experimental group 2 with a high addition level of 0.10%, indicating that the low addition level of 0.05% has a better effect window in promoting the increase of milk fat, non-fat solids, milk protein, and lactose content in sow colostrum. At the same time, it also indicates that the technical effect of the sow feed additive of the present invention in promoting the increase of milk fat, non-fat solids, milk protein, and lactose content in sow colostrum is not linearly enhanced with the increase of the addition level of the present invention.

[0070] Table 4 Effects of different treatments on the growth performance of offspring piglets

[0071]

[0072] Data in the table are expressed as mean. Different lowercase letters in the same row indicate significant differences (P<0.05).

[0073] Table 4 shows that, compared with the control group, the birth weight of piglets in experimental group 1 was significantly increased (P<0.05), while the difference in experimental group 2 was not significant but showed a decreasing trend; compared with experimental group 1, the birth weight of piglets in experimental group 2 was significantly decreased (P<0.05). This indicates that applying the sow feed additive of the present invention at a low addition level of 0.05% can promote the increase of piglet birth weight, and experimental group 1 has a higher potential to promote the increase of piglet birth weight than experimental group 2. This shows that the low addition level of 0.05% has a better effect window in promoting the increase of piglet birth weight. At the same time, it also shows that the technical effect of the sow feed additive of the present invention in promoting the increase of piglet birth weight is not linearly enhanced with the increase of the addition level of the present invention.

[0074] Compared with the control group, the weaning litter weight of piglets in experimental group 1 was significantly increased (P<0.05), while the difference in experimental group 2 was not significant. Compared with experimental group 1, the weaning litter weight of piglets in experimental group 2 was not significantly different, but showed a decreasing trend. This indicates that applying the sow feed additive of the present invention at a low addition level of 0.05% can promote the increase of weaning litter weight of piglets. Furthermore, the low addition level of 0.05% has a better effect window in promoting the increase of piglet birth weight, also indicating that the technical effect of the sow feed additive of the present invention in promoting the increase of piglet birth weight is not linearly enhanced with the increase of the addition level.

[0075] Compared with the control group, the litter weight gain of piglets in both experimental groups 1 and 2 was significantly improved (P<0.05), indicating that the sow feed additive of the present invention can promote litter weight gain. Furthermore, compared with the control group, the litter weight gain of piglets in experimental group 1 increased by 23.61%, and that in experimental group 2 increased by 19.26%, showing that experimental group 1 has a higher potential for promoting litter weight gain. This indicates that a low addition amount of 0.05% has a better effect window in promoting litter weight gain, and also shows that the technical effect of the sow feed additive of the present invention in promoting litter weight gain does not increase linearly with increasing addition amount.

[0076] Compared with the control group, the average daily weight gain of piglets in both experimental groups 1 and 2 was significantly increased (P<0.05), indicating that the sow feed additive of the present invention can promote the increase of average daily weight gain of piglets; furthermore, compared with the control group, the average daily weight gain of piglets in experimental group 1 increased by 12.47%, and the average daily weight gain of piglets in experimental group 2 increased by 14.55%. The difference in average daily weight gain of piglets in experimental group 2 compared with experimental group 1 was not significant.

[0077] Furthermore, in order to study the safety of feeding the sow feed additive of the present invention to sows throughout the entire cycle from sow mating to piglet weaning, during the implementation of the above-mentioned Example 2, the following data were also collected simultaneously regarding sow feed intake, sow health status, sow reproductive status, and piglet survival rate. The results are shown in Table 5.

[0078] Table 5 Results of the sow feeding safety trial

[0079]

[0080] The values ​​in the table are expressed as averages or occurrences. Values ​​in the same row with the same lowercase letter indicate no significant difference (P>0.05). Occurrence indicators without a subscript are used for safety description.

[0081] Table 5 shows that in experimental group 1, the average feed intake of sows during gestation was 2.51 kg / d, and the average feed intake during lactation was 5.68 kg / d. Compared with the control group and experimental group 2, neither of these indicators showed a significant difference (P>0.05), indicating that the addition of the sow feed additive of this invention did not reduce sow feed intake and would not affect feed intake during gestation and lactation. The incidence of constipation in sows in experimental group 1 was 5.0%, lower than that in the control group, and no diarrhea was observed in any group. No abortions were observed in any group, and the total number of stillbirths or mummified fetuses did not increase abnormally. The number of abnormally culled sows was 0, and no other adverse reactions related to the additive, such as abnormal mental state, feeding behavior, skin condition, or movement, were observed. The weaning survival rate of piglets increased from 80.10% in the control group to 85.80% in experimental group 1. The above results indicate that the sow feed additives of the present invention, with added 0.05% and 0.10%, are suitable for continuous feeding of sows throughout the entire breeding to weaning cycle, and have good safety and feasibility for large-scale application.

[0082] Furthermore, in addition to conducting Example 2 above, a comparative feeding experiment was also conducted on sows and other pigs fed with conventional selenium-based feed products containing selenium. In this comparative experiment, yeast selenium was used as a typical control for organic selenium-based feed products, and sodium selenite was used as a typical control for inorganic selenium-based feed products.

[0083] This comparative experiment, conducted under the same basal diet, sow breed, parity, body condition, feeding management, and feeding cycle as Example 2, added control group 1 and control group 2, and was carried out simultaneously and under the same conditions as the feeding experiment in Example 2.

[0084] The feeds given to the sows in each treatment group involved in this comparative experiment are as follows:

[0085] Control group (i.e., the control group in Example 2): basal diet.

[0086] Experimental Group 1 (i.e., Experimental Group 1 in Example 2): 0.05% of the pig feed additive prepared in Example 1 of this invention was added to the basal diet and mixed evenly to obtain the feed for feeding the sows in Experimental Group 1.

[0087] Control Group 1: Yeast selenium was added to the basal diet, and the amount of selenium added was calculated to be the same as that added in Experimental Group 1. After being mixed evenly, the feed for feeding sows in Control Group 1 was prepared.

[0088] Control Group 2: Sodium selenite was added to the basal diet to calculate the amount of selenium added, making it the same as the amount of selenium added in Experimental Group 1. After mixing evenly, the feed for sows in Control Group 2 was prepared.

[0089] The selenium content in the feed for sows in the above-prepared experimental group 1, control group 1, and control group 2 was all <0.5 mg / kg.

[0090] Data on average daily milk production of sows, colostrum immunoglobulin levels, and growth performance of offspring piglets were collected. The results are shown in Table 6.

[0091] Table 6. Comparative Experiment and Results of Feeding Products with Conventional Selenium Sources of Equal Selenium Content

[0092]

[0093] Data in the table are expressed as mean. Different lowercase letters in the same row indicate significant differences (P<0.05).

[0094] As shown in Table 6, the same amount of selenium, 0.41 mg / kg, was added to the basal diet of sows in experimental group 1, control group 1, and control group 2.

[0095] Regarding the impact on the average daily milk production of sows, compared with the control group, both experimental group 1 and control group 1 significantly increased the average daily milk production of sows. The difference in control group 2 was not significant, but there was a trend of increasing the average daily milk production of sows. Among them, experimental group 1 had the highest average daily milk production of sows, with an average daily milk production of 9.97 kg / d, which was significantly higher than that of the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared with the control group, the average daily milk production of sows in experimental group 1 increased by 23.54%, compared with control group 1, the average daily milk production of sows in experimental group 1 increased by 7.44%, and compared with control group 2, the average daily milk production of sows in experimental group 1 increased by 13.04%.

[0096] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the average daily milk production of sows in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and compared with control group 1, the average daily milk production of sows in control group 2 was not significantly different. This indicates that in terms of the effect on the average daily milk production of sows, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly increase the average daily milk production of sows, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0097] Regarding the effect on the immune quality of sow colostrum—specifically, the colostrum IgG content—was significantly increased in both experimental group 1 and control group 1 compared to the control group. Control group 2 showed no significant difference, but exhibited a trend towards increased colostrum IgG content. Experimental group 1 had the highest colostrum IgG content, reaching 85.33 g / L, significantly higher than the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared to the control group, the colostrum IgG content in experimental group 1 increased by 29.07%, compared to control group 1 by 11.66%, and compared to control group 2 by 18.22%.

[0098] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the sow colostrum IgG content in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and, compared with control group 1, the sow colostrum IgG content in control group 2 was not significantly different. This indicates that in terms of the effect on the immune quality of sow colostrum - colostrum IgG content, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly improve the immune quality of sow colostrum - colostrum IgG content, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0099] Regarding the effect on the immune quality of sow colostrum—specifically, the colostrum IgA content—compared to the control group, both experimental group 1 and control group 1 significantly increased the colostrum IgA content in sows. Control group 2 showed no significant difference, but exhibited a trend towards increasing colostrum IgA content. Experimental group 1 had the highest colostrum IgA content, at 11.87 g / L, significantly higher than the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared to the control group, the colostrum IgA content in experimental group 1 increased by 15.80%, compared to control group 1 by 6.74%, and compared to control group 2 by 10.11%.

[0100] Furthermore, under the condition that the functional selenium addition amount was equal in experimental group 1, control group 1, and control group 2 (all 0.41 mg / kg), the IgA content of sow colostrum in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and, compared with control group 1, the IgA content of sow colostrum in control group 2 was not significantly different. This indicates that in terms of the effect on the immune quality of sow colostrum - colostrum IgA content, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly improve the immune quality of sow colostrum - colostrum IgA content, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0101] Regarding the effect on the immune quality of sow colostrum—specifically, the colostrum IgM content—compared to the control group, both experimental group 1 and control group 1 significantly increased the colostrum IgM content in sows. Control group 2 showed no significant difference, but exhibited a trend towards increasing colostrum IgM content. Experimental group 1 had the highest colostrum IgM content, at 6.21 g / L, significantly higher than the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared to the control group, the colostrum IgM content in experimental group 1 increased by 45.43%, compared to control group 1 by 18.51%, and compared to control group 2 by 27.78%.

[0102] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the IgM content in sow colostrum in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and, compared with control group 1, the IgM content in sow colostrum in control group 2 was not significantly different. This indicates that in terms of the effect on the immune quality of sow colostrum - colostrum IgM content, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly improve the immune quality of sow colostrum - colostrum IgM content, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0103] Regarding the impact on piglet production performance—weaning litter weight—both experimental group 1 and control group 1 significantly increased the weaning litter weight of piglets compared to the control group. Control group 2 showed no significant difference, but exhibited a trend towards increasing weaning litter weight. Experimental group 1 had the highest weaning litter weight, at 71.97 kg, significantly higher than the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared to the control group, the weaning litter weight of piglets in experimental group 1 increased by 15.73%; compared to control group 1, it increased by 6.09%; and compared to control group 2, it increased by 9.53%.

[0104] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the weaning litter weight of piglets in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and, compared with control group 1, the weaning litter weight of piglets in control group 2 was not significantly different. This indicates that in terms of the effect on piglet production performance - weaning litter weight, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly increase the weaning litter weight of piglets, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0105] Regarding the impact on piglet production performance—litter weight gain—both experimental group 1 and control group 1 significantly improved litter weight gain compared to the control group. Control group 2 showed no significant difference, but exhibited a trend towards improved litter weight gain. Experimental group 1 showed the highest litter weight gain, at 52.36 kg, significantly higher than the control group, control group 1, and control group 2 (P<0.05). Furthermore, compared to the control group, the litter weight gain in experimental group 1 increased by 23.61%; compared to control group 1, it increased by 9.04%; and compared to control group 2, it increased by 14.12%.

[0106] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the litter weight gain of piglets in experimental group 1 was significantly higher than that in control group 1 and control group 2 (P<0.05); and, compared with control group 1, the litter weight gain of piglets in control group 2 was not significantly different. This indicates that in terms of the effect on piglet production performance - litter weight gain, there is no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of the present invention can significantly improve the litter weight gain of piglets, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0107] Regarding the impact on piglet production performance—average daily weight gain—both experimental group 1 and control group 1 significantly increased the average daily weight gain of piglets compared to the control group. Control group 2 showed no significant difference, but exhibited a trend towards increasing the average daily weight gain of piglets. Experimental group 1 had the highest average daily weight gain, at 187.48 g, significantly higher than both the control and control groups (P<0.05). Furthermore, compared to the control group, the average daily weight gain of piglets in experimental group 1 increased by 12.47%, and compared to control group 2, it increased by 8.05%.

[0108] Furthermore, under the condition that the functional selenium equivalent addition amount in experimental group 1, control group 1, and control group 2 was equal (all 0.41 mg / kg), the average daily weight gain of piglets in experimental group 1 was significantly higher than that in control group 2 (P<0.05), while the difference between experimental group 1 and control group 2 was not significant. However, compared with control group 1, experimental group 1 showed a trend of increasing the average daily weight gain of piglets. Furthermore, compared with control group 1, the average daily weight gain of piglets in control group 2 was not significantly different, indicating that in terms of the effect on piglet production performance - average daily weight gain, there was no difference in the effect of organic selenium source and inorganic selenium source feed products. The sow feed additive of this invention can significantly improve the average daily weight gain of piglets, and the improvement effect is better than that of organic selenium source and inorganic selenium source feed products with the same selenium addition amount.

[0109] The sow feed additive of this invention can significantly increase the average daily milk production of sows, the content of IgG, IgA, and IgM in sow colostrum, the litter weight at weaning, the litter weight gain, and the average daily weight gain of piglets. Furthermore, the improvement effect is superior to that of feed products containing the same amount of organic or inorganic selenium sources. This indicates that the above-mentioned effects of the sow feed additive of this invention are not solely dependent on selenium, but rather derived from the efficacy of the entire dry powder of *Capsella bursa-pastoris*.

Claims

1. Application of whole plant powder of *Capsella bursa-pastoris* in the preparation of feed additives that can improve the average daily milk production of sows, increase the immunoglobulin content of sow colostrum, improve the quality of sow colostrum, and enhance the growth performance of offspring piglets.

2. The application as described in claim 1, characterized in that, The method of increasing the immunoglobulin content of sow colostrum is to increase the content of at least one of IgG, IgA and IgM in sow colostrum.

3. The application as described in claim 1, characterized in that, The improvement of sow colostrum quality is achieved by increasing the content of at least one of milk fat, non-fat solids, milk protein, and lactose in sow colostrum.

4. The application as described in claim 1, characterized in that, The improvement of offspring piglet growth performance refers to: improving at least one of the following: birth weight, weaning litter weight, litter weight gain, and average daily weight gain of offspring piglets.

5. The application as described in claim 1, characterized in that, The preparation method of the whole plant powder of *Capsella bursa-pastoris* includes the following steps: selecting, washing, draining, drying and pulverizing fresh whole plant of *Capsella bursa-pastoris* to obtain whole plant powder of *Capsella bursa-pastoris*.

6. The application as described in claim 1, characterized in that, The whole plant powder of *Corydalis oryzae* is the whole plant powder of *Corydalis oryzae*.

7. The application as described in claim 1, characterized in that, The amount of the whole plant dry powder of the broken rice shepherd's purse added to the sow's daily diet is 0.05%.

8. The application method as described in claim 1: Feed the sow the whole plant dry powder of *Cephalotaxus fortunei* from the day of mating until the 21st day of lactation.

9. A sow feed additive, characterized in that, It contains the whole plant dry powder of *Cephalotaxus fortunei* as described in claim 1.

10. A sow feed, characterized in that, The sow feed comprises the sow feed additive of claim 9.

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