A livestock and poultry feed additive containing honeysuckle branches, a preparation method and application thereof
Patent Information
- Application Number
- CN202611153879.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-07-31
- Publication Date
- 2026-10-23
AI Technical Summary
[0005]本发明的目的，旨在要提供一种含有金银花枝条的畜禽饲料添加剂，以解决金银花枝条资源利用问题的同时提供一种畜禽饲料添加剂；
[0026]①本发明提供的含有金银花枝条的畜禽饲料添加剂，以金银花采收修剪废弃枝条经低温干燥粉碎所得全粉为核心原料，复配益生菌粉及具有多孔吸附功能的载体，其中金银花枝条全粉完整保留了绿原酸、黄酮类及多糖等天然活性成分，载体通过对益生菌的物理吸附负载有效维持了菌粉在储存过程中的活力，三者协同发挥植物源活性物质的抗菌抗炎作用与肠道微生态调节功能，能够增强禽类免疫力、降低腹泻率和死淘率、改善饲料转化效率，适用于替代或减少畜禽养殖中抗生素的使用。
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Abstract
Description
Technical Field
[0001] This invention belongs to the field of feed additives, specifically fermented feed, and more specifically, a livestock and poultry feed additive containing honeysuckle branches, its preparation method, and its application. Background Technology
[0002] Honeysuckle (Lonicera japonica Thunb.), a traditional medicinal plant, has had its chlorogenic acid, luteolin, and other active ingredients in its flower buds proven effective in antibacterial, anti-inflammatory, and antiviral properties, and is widely used in the pharmaceutical and health product fields. However, the large amount of branches generated during the annual honeysuckle harvesting and pruning process has long been treated as agricultural waste, either burned or discarded, resulting in a waste of biomass resources and an environmental burden. Meanwhile, the widespread use of antibiotics in poultry farming to prevent disease and promote growth has led to increased bacterial resistance and drug residues, posing food safety risks. Developing green and safe plant-based feed additives to replace antibiotics has become a crucial area for the industry to explore.
[0003] Regarding the application of honeysuckle resources in the field of feed additives, some technologies have been explored. For example, the effective components of honeysuckle stems and leaves are extracted using water extraction or alcohol extraction. However, this technology still has certain shortcomings: the extraction process often involves a long heating and boiling process, with temperatures reaching hundreds of degrees Celsius, and the processing time often lasting more than ten hours. Chlorogenic acid, flavonoids, and other phenolic acids and flavonoid components have obvious thermal instability and are prone to oxidative decomposition or structural transformation under high temperature and long-term extraction conditions, resulting in a significant reduction in the actual retention rate of the target active ingredients in the final product. More importantly, the extraction operation essentially only obtains the water-soluble or alcohol-soluble components from the plant raw material, while the crude fiber, lignin, and some fat-soluble components, which constitute the majority of the branch biomass, are discarded as waste, failing to achieve full utilization of the resource. This approach not only increases the energy consumption and equipment investment in extraction, concentration, and drying, raising production costs, but also requires further treatment of the discarded residue, further exacerbating the waste disposal pressure.
[0004] Furthermore, most existing technologies are not specifically designed for the physiological characteristics of the poultry gut and the application scenarios. Poultry have relatively short digestive tracts and rapid digestion, requiring high release rates and absorption efficiency of active ingredients in additives. Existing extract-based products dissolve rapidly after entering the digestive tract, lacking a sustained-release mechanism, meaning that the active ingredients are largely metabolized and eliminated before reaching the site of action. Methods relying on microbial fermentation neglect the synergistic support of plant-derived active substances for intestinal barrier function and immune regulation. Summary of the Invention
[0005] The purpose of this invention is to provide a livestock and poultry feed additive containing honeysuckle branches, so as to solve the problem of honeysuckle branch resource utilization and provide a livestock and poultry feed additive.
[0006] Another objective of this invention is to provide a method for preparing and using the above-mentioned livestock and poultry feed additive containing honeysuckle branches, so as to achieve the purpose of rapid preparation and use of the feed additive.
[0007] To achieve the above objectives, the technical solution adopted by the present invention is as follows:
[0008] A livestock and poultry feed additive containing honeysuckle branches.
[0009] As a limitation, it consists of the following raw materials in parts by weight: 50-90 parts honeysuckle branch powder, 5-10 parts probiotic powder, and 10-50 parts carrier;
[0010] The honeysuckle branch powder is made by crushing the branches obtained after honeysuckle is harvested and pruned.
[0011] The probiotic powder contains at least one of lactic acid bacteria, bifidobacteria, yeast, Bacillus pastoris, and Lactobacillus acidogeneticus.
[0012] The carrier is at least one of zeolite powder, montmorillonite, bentonite, silica, corn gluten meal, soybean meal, and wheat bran.
[0013] As another limitation, the honeysuckle branches are selected from at least one of the following: Yate Red Honeysuckle, Yate Liben Honeysuckle, or Qinghua No. 1 Honeysuckle.
[0014] As a third limitation, the probiotic powder includes Bacillus Pasteurella multocida powder and Lactobacillus acidogeneticus powder.
[0015] As a further limitation, the total number of live bacteria in the probiotic powder is not less than 1×10⁻⁶. 8 CFU / g.
[0016] This invention also provides a method for preparing the above-mentioned livestock and poultry feed additive containing honeysuckle branches, the method comprising the following steps performed sequentially:
[0017] S1. Collect the pruned honeysuckle branches, remove impurities, wash them with clean water, and dry them;
[0018] S2. Crush the dried honeysuckle branches and sieve them to obtain honeysuckle branch powder;
[0019] S3. Weigh out the honeysuckle branch powder, probiotic powder and carrier, and mix them according to the stated weight proportions to obtain the feed additive.
[0020] As a limitation, the drying temperature in S1 is 60-75℃, and the drying is carried out until the moisture content is less than 12%.
[0021] As another limitation, the sieving in S2 is through an 80-200 mesh sieve.
[0022] This invention also provides the application of the above-mentioned livestock and poultry feed additive containing honeysuckle branches in the preparation of livestock and poultry feed.
[0023] As a limitation, the poultry mentioned are broiler chickens, laying hens, ducks, or geese.
[0024] As another limitation, the amount of the feed additive added to the complete compound feed for livestock and poultry accounts for 0.5%-3.0% of the total weight of the complete compound feed for livestock and poultry.
[0025] By adopting the above technical solution, the technical progress achieved by this invention compared with the prior art is as follows:
[0026] ① The livestock and poultry feed additive containing honeysuckle branches provided by this invention uses honeysuckle harvested and pruned waste branches, which are dried and pulverized at low temperature as the core raw material. It is compounded with probiotic powder and a carrier with porous adsorption function. The honeysuckle branch powder completely retains natural active ingredients such as chlorogenic acid, flavonoids and polysaccharides. The carrier effectively maintains the vitality of the probiotic powder during storage by physically adsorbing and loading the probiotics. The three work together to exert the antibacterial and anti-inflammatory effects of plant-derived active substances and the intestinal microecological regulation function, which can enhance poultry immunity, reduce diarrhea rate and mortality rate, and improve feed conversion efficiency. It is suitable for replacing or reducing the use of antibiotics in livestock and poultry farming.
[0027] ② The method for preparing livestock and poultry feed additives containing honeysuckle branches provided by this invention adopts a physical processing method of low-temperature drying at 60-75℃ combined with direct pulverization. This avoids the oxidative degradation of heat-sensitive components such as chlorogenic acid caused by prolonged high-temperature heating in traditional water extraction or alcohol extraction processes. It eliminates the need for complex extraction, concentration, and drying equipment, significantly simplifies the process, greatly reduces production energy consumption, and simultaneously achieves the resource utilization of all components of waste branches with no residue discharge. During the mixing process, the ambient temperature does not exceed 30℃ and the relative humidity is controlled at 40%-60%. Combined with the adsorption and protection function of the carrier, this further ensures the stability of live bacteria during processing and storage.
[0028] This invention is applicable to converting waste branches from the honeysuckle industry into functional poultry feed additives. The prepared product can exert growth-promoting and anti-diarrheal effects when added at 0.5%-3.0% to complete poultry feed. The preparation method of this invention does not require complicated extraction processes, is simple to operate, has low energy consumption, is suitable for large-scale industrial production, and is easy to promote and apply in antibiotic-free breeding production. Detailed Implementation
[0029] The present invention will be further described in detail below through specific embodiments. It should be understood that the described embodiments are only for explaining the present invention and do not limit the present invention.
[0030] Example 1
[0031] This embodiment is a livestock and poultry feed additive containing honeysuckle branches and its preparation method. The livestock and poultry feed additive containing honeysuckle branches consists of 75 parts by weight of honeysuckle branch powder, 5 parts by weight of probiotic powder and 20 parts by weight of zeolite powder.
[0032] Its preparation method includes the following steps performed sequentially:
[0033] S1. Collect 100kg of current-year branches obtained after pruning of Yate Red Honeysuckle, remove impurities, wash with clean water, place in a drying room and dry at 65℃ until the moisture content is 10% to obtain dried branches;
[0034] S2. After drying, the branches are crushed using a pulverizer and passed through a 100-mesh sieve to obtain approximately 85 kg of honeysuckle branch powder;
[0035] S3. Weigh 75 kg of honeysuckle branch powder, 5 kg of probiotic powder and 20 kg of zeolite powder obtained in S2, put them into a double helix cone mixer and mix for 20 minutes to obtain a livestock and poultry feed additive containing honeysuckle branches.
[0036] The probiotic powder is a mixture of Bacillus Pasteurella multocida powder and Lactobacillus acidogenetic powder in a 1:1 weight ratio, with a total live bacteria count of 2 × 10⁻⁶. 8 CFU / g.
[0037] Comparative Example 1
[0038] This comparative example illustrates a method for preparing a stem and leaf extract, comprising the following steps:
[0039] Collect honeysuckle stems and leaves, pulverize them to 60-80 mesh, put them into an extraction tank, add an appropriate amount of water, and soak for 12 hours; heat to 80℃ and extract for 12 hours, filter and collect the extract; concentrate under reduced pressure to obtain an extract, and finally dry and grind it into powder to obtain the stem and leaf extract.
[0040] Effect Experiment Example 1
[0041] This experimental example verifies and tests the application effect of the livestock and poultry feed additive containing honeysuckle branches prepared in Example 1 in broiler farming. Details are as follows:
[0042] Three hundred healthy AA broiler chickens aged one day were randomly divided into two groups, with five replicates per group and thirty chickens per replicate. The control group was fed a basal diet, while the experimental group was fed a basal diet supplemented with 1.5% of the livestock and poultry feed additive containing honeysuckle branches prepared in Example 1. The experiment lasted for 42 days, and the indicators measured included growth performance, health status, immune indicators, and antioxidant indicators.
[0043] The test results are as follows: the final weight of broilers in the experimental group at 42 days of age was 4.8% higher than that in the control group, and the feed conversion ratio was 5.2% lower; the diarrhea rate of broilers in the experimental group was significantly lower than that in the control group, and the mortality rate was 3.5% lower; the Newcastle disease antibody titer and IgG level in the serum of broilers in the experimental group were significantly higher than those in the control group; the total antioxidant capacity in the serum and liver of broilers in the experimental group was significantly improved, and the malondialdehyde content was significantly reduced.
[0044] The above results indicate that when the feed additive containing honeysuckle branches provided by this invention is added at 1.5% to the daily diet of broilers, it can effectively promote broiler growth, improve feed efficiency, enhance the body's immune function and antioxidant capacity, and reduce the incidence of disease.
[0045] Effect Experiment Example 2
[0046] This experimental example verifies and tests the application effect of the livestock and poultry feed additive containing honeysuckle branches prepared in Example 1 in laying hen farming. Details are as follows:
[0047] Four hundred Hy-Line Brown laying hens aged 240 days were randomly divided into two groups, with four replicates per group and 50 hens per replicate. The control group was fed a basal laying hen diet, while the experimental group was fed a basal laying hen diet supplemented with 1.0% of the livestock and poultry feed additive containing honeysuckle branches prepared in Example 1. The experiment lasted for 8 weeks, and the indicators measured included production performance, egg quality, and gut health.
[0048] The test results are as follows: The egg production rate of the experimental group was 2.5% higher than that of the control group, the average egg weight was slightly increased, and the broken egg rate was reduced; the Haugh unit of the eggs in the experimental group was increased, the yolk color was better, and the quality stability during storage was better; the feces of the experimental group hens were better formed, and the intestinal flora structure was improved.
[0049] The above results indicate that when the feed additive containing honeysuckle branches provided by this invention is added at 1.0% to the daily diet of laying hens, it can effectively improve the laying performance and egg quality of laying hens and maintain intestinal health.
[0050] Effect Experiment Example 3
[0051] This experimental example compares the retention of active ingredients in the honeysuckle branch powder prepared in Example 1 with that in the stem and leaf extract prepared in Comparative Example 1. Details are as follows:
[0052] Honeysuckle branches from the same batch were processed according to steps S1-S2 of Example 1 (drying at 65℃ until the moisture content is below 12%, pulverizing through a 100-mesh sieve to obtain honeysuckle branch powder) and step 1 of Comparative Example 1 (soaking in water for 12 hours, heating to 80℃ for 12 hours, filtering and collecting the extract, concentrating under reduced pressure, drying and grinding into powder to obtain stem and leaf extract). The chlorogenic acid content in the products obtained by both methods was determined using high-performance liquid chromatography (HPLC), the chlorogenic acid retention rate was calculated, and the retention of crude fiber was observed.
[0053] The test results are as follows: In Example 1, the chlorogenic acid retention rate of the honeysuckle branch powder was 92.6%, and all crude fiber was retained. The product contained a mixture of all components, including chlorogenic acid, flavonoids, crude fiber, polysaccharides, crude protein, and minerals. In Comparative Example 1, the chlorogenic acid retention rate of the stem and leaf extract was only 47.3%, and crude fiber was basically removed. The product mainly consisted of water-soluble components such as enriched chlorogenic acid and flavonoids.
[0054] The above results indicate that the physical processing method of low-temperature drying and direct pulverization used in this invention has a significantly higher chlorogenic acid retention rate than the stem and leaf extract route of Comparative Example 1, and completely preserves all natural components such as crude fiber and polysaccharides in the branches.
[0055] Comparative Example 1 involves multiple processes such as long-term high-temperature extraction, concentration and drying, resulting in severe degradation of heat-sensitive components such as chlorogenic acid, and its production cost is significantly higher than that of this invention.
[0056] Therefore, this invention eliminates complex processes such as extraction, concentration, and drying, while maximizing the retention of all active ingredients and achieving efficient resource utilization of waste branches. The process is simplified, energy consumption is reduced, and there is no consumption of chemical reagents or discharge of medicinal residues.
[0057] Examples 2-7
[0058] Examples 2-7 are methods for preparing livestock and poultry feed additives containing honeysuckle branches. Their steps are basically the same as in Example 1, differing only in the amount of raw materials and process parameters. See Table 1 for details.
[0059] Table 1. Summary of Control Parameters for Examples 2-7
[0060]
[0061] The total number of live bacteria in the above-mentioned probiotic powder is not less than 1×10⁶. 8 CFU / g, the contents of other parts of Examples 2-7 are the same as those of Example 1. The livestock and poultry feed additives containing honeysuckle branches are added at an amount of 0.5%, 1.0%, 1.5%, 2.0%, 2.5% or 3.0% of the total weight of complete compound feed for feeding broilers, laying hens, ducks or geese.
Claims
1. A livestock and poultry feed additive containing honeysuckle branches, characterized in that, It consists of the following ingredients in parts by weight: 50-90 parts honeysuckle branch powder, 5-10 parts probiotic powder, and 10-50 parts carrier; The honeysuckle branch powder is made by crushing the branches obtained after honeysuckle is harvested and pruned. The probiotic powder contains at least one of lactic acid bacteria, bifidobacteria, yeast, Bacillus pastoris, and Lactobacillus acidogeneticus. The carrier is at least one of zeolite powder, montmorillonite, bentonite, silica, corn gluten meal, soybean meal, and wheat bran.
2. The livestock and poultry feed additive containing honeysuckle branches according to claim 1, characterized in that, The honeysuckle branches are selected from at least one of the following: Yate Red Honeysuckle, Yate Liben Honeysuckle, or Qinghua No. 1 Honeysuckle.
3. A livestock and poultry feed additive containing honeysuckle branches according to claim 1 or 2, characterized in that, The probiotic powder contains Bacillus Pasteurella multocida powder and Lactobacillus acidogenetic powder.
4. The livestock and poultry feed additive containing honeysuckle branches according to claim 3, characterized in that, The total number of live bacteria in the probiotic powder is not less than 1×10⁻⁶. 8 CFU / g.
5. A method for preparing a livestock and poultry feed additive containing honeysuckle branches as described in any one of claims 1-4, characterized in that, Includes the following steps: S1. Collect the pruned honeysuckle branches, remove impurities, wash them with clean water, and dry them; S2. Crush the dried honeysuckle branches and sieve them to obtain honeysuckle branch powder; S3. Weigh out the honeysuckle branch powder, probiotic powder and carrier, and mix them according to the stated weight proportions to obtain the feed additive.
6. The method for preparing livestock and poultry feed additive containing honeysuckle branches according to claim 5, characterized in that, The drying temperature in S1 is 60-75℃, and the product is dried until the moisture content is below 12%.
7. The method for preparing livestock and poultry feed additive containing honeysuckle branches according to claim 5 or 6, characterized in that, The sieving in S2 is through an 80-200 mesh sieve.
8. The use of a livestock and poultry feed additive containing honeysuckle branches as described in any one of claims 1-4, or a livestock and poultry feed additive containing honeysuckle branches prepared by any one of claims 5-7, in the preparation of livestock and poultry feed.
9. The application according to claim 8, characterized in that, The poultry are broilers, laying hens, ducks, or geese.
10. The application according to claim 8 or 9, characterized in that, The feed additive is added to complete compound feed for livestock and poultry at a rate of 0.5%-3.0% of the total weight of the complete compound feed.