Sensitive skin care composition with antioxidant and anti-aging efficacy and use thereof

Abstract

The application discloses a sensitive skin care composition with antioxidant and anti-aging effects, and relates to the technical field of skin care.The core active ingredients of the composition include schisandra chinensis extract, laminaria digitata extract, centaurea cyanus flower extract and leucanthemum vulgare flower extract.The laminaria digitata extract promotes collagen synthesis, the schisandra chinensis extract can eliminate free radicals and improve cell activity, the leucanthemum vulgare flower extract can resist glycation and photoaging, and the centaurea cyanus flower extract repairs the skin barrier;the effects of the above components are complementary, and a multi-dimensional anti-aging system of 'promoting new growth-preventing damage-reducing irritation' is constructed.The antioxidant system of the composition is perfect, the irritation is extremely low, and the composition can effectively improve problems such as oxidation and dullness, fine line relaxation and the like of sensitive skin, is suitable for preparation of sensitive skin anti-aging care products, and has remarkable skin care effect and wide applicability.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a skincare composition for sensitive skin with antioxidant and anti-aging effects and its application. Background Technology

[0002] With the continuous deterioration of the ecological environment, the ubiquitous radiation from electronic devices, and the widespread unhealthy lifestyle habits of modern people such as staying up late and irregular sleep patterns, skin aging problems are increasingly affecting younger people. Issues such as oxidative damage, photoaging, fine lines, and sagging skin are becoming more and more common. At the same time, the number and proportion of people with sensitive skin are also increasing year by year, making sensitive skin care a key sub-segment in the beauty and skincare industry.

[0003] Compared to healthy skin, sensitive skin suffers from structural damage to its skin barrier. This manifests as a thinner stratum corneum, weaker moisture retention, and lower tolerance and inflammation threshold. It is extremely vulnerable to changes in the external environment and external stimuli, easily leading to redness, dryness, burning, stinging, itching, and other skin problems. Furthermore, sensitive skin has a lower efficiency in clearing free radicals, failing to neutralize harmful free radicals in time. This directly accelerates collagen loss and degradation, resulting in a much faster and more pronounced aging process compared to normal healthy skin.

[0004] Most mainstream anti-aging skincare products on the market today are formulated and developed for healthy skin, with core active ingredients such as retinol, high-concentration fruit acids, and various active peptides. While these ingredients can achieve effective anti-aging, reduce fine lines, and firm the skin, they generally have a high irritant rate. They can easily damage the already fragile skin barrier of sensitive skin, leading to a series of adverse reactions such as allergies, persistent redness, breakouts, burning, and stinging. Therefore, they are not suitable for people with sensitive skin.

[0005] Currently, most skincare products specifically developed for sensitive skin are limited to basic soothing and moisturizing functions. Their formulas are simple and lack a multi-dimensional, comprehensive anti-aging system that integrates anti-oxidation, anti-glycation, and collagen regeneration. These products can only temporarily relieve symptoms such as dryness and redness on the surface of sensitive skin. They cannot eliminate free radicals, block collagen loss, or repair the aging and damaged skin base from the root cause. Their anti-aging effects are weak and singular, failing to meet the core anti-aging and repair needs of sensitive skin.

[0006] In addition, most plant-based anti-aging formulas at present still have obvious technical shortcomings. They generally suffer from problems such as unscientific ingredient ratios, overlapping efficacy dimensions, and weak synergistic effects of ingredients. They are unable to build a comprehensive, closed-loop anti-aging and repair mechanism, and it is difficult to simultaneously meet the multiple skin care needs of sensitive skin barrier repair, powerful anti-oxidation, and long-lasting anti-aging and firming.

[0007] In summary, developing a skincare formula with gentle and safe ingredients, excellent synergistic properties, and the ability to simultaneously repair the skin barrier, provide multi-dimensional antioxidant protection, and inhibit skin aging is the core research direction in the field of anti-aging skincare technology for sensitive skin, and also a pressing pain point that the market urgently needs to address. Summary of the Invention

[0008] This invention aims to overcome the shortcomings of existing anti-aging skincare products for sensitive skin, such as high irritation, single efficacy, incomplete anti-aging system, and inability to simultaneously address soothing repair and multi-dimensional anti-aging. It provides a skincare composition for sensitive skin that is gentle, scientifically formulated, and has synergistic effects, and is designed to combat oxidation and delay aging. This invention solves the technical problems of sensitive skin being prone to allergies, having weak free radical scavenging ability, rapid collagen loss, and being unable to simultaneously address barrier repair and anti-aging.

[0009] To achieve the above objectives, the present invention adopts the following technical solution: In a first aspect, the present invention provides a skin care composition for sensitive skin with antioxidant and anti-aging effects, comprising, by weight: 3-7 parts of Schisandra chinensis extract, 10-15 parts of Laminaria japonica extract, 5-10 parts of Cornflower extract, and 3-8 parts of Chrysanthemum indicum extract.

[0010] Preferably, the skin care composition comprises, by weight: 4-6 parts of Schisandra chinensis extract, 12-14 parts of Laminaria japonica extract, 6-8 parts of Cornflower extract, and 5-7 parts of Chrysanthemum indicum extract.

[0011] Preferably, the skin care composition comprises, by weight: 5 parts of Schisandra chinensis extract, 13 parts of Laminaria japonica extract, 7 parts of Cornflower extract, and 6 parts of Chrysanthemum indicum extract.

[0012] In a second aspect, the present invention provides a method for preparing a skin care composition as described in the first aspect, wherein Schisandra chinensis extract, Laminaria japonica extract, Cornflower extract, and Chrysanthemum indicum extract are mixed evenly to obtain the composition.

[0013] The skincare composition, by weight, comprises: 3-7 parts of Schisandra chinensis extract, 10-15 parts of Laminaria japonica extract, 5-10 parts of Cornflower extract, and 3-8 parts of Chrysanthemum indicum extract.

[0014] Preferably, the skin care composition comprises, by weight: 4-6 parts of Schisandra chinensis extract, 12-14 parts of Laminaria japonica extract, 6-8 parts of Cornflower extract, and 5-7 parts of Chrysanthemum indicum extract.

[0015] Preferably, the skin care composition comprises, by weight: 5 parts of Schisandra chinensis extract, 13 parts of Laminaria japonica extract, 7 parts of Cornflower extract, and 6 parts of Chrysanthemum indicum extract.

[0016] Thirdly, the present invention provides a skin care product comprising the skin care composition as described in the first aspect, wherein the content of the skin care composition is 0.1-10 wt%.

[0017] Preferably, the content of the skin care composition is 0.5-8 wt%.

[0018] Preferably, the skin care product further contains cosmetically acceptable excipients, including one or more of moisturizers, thickeners, emollients, antioxidants, and deionized water.

[0019] Preferably, the humectant is at least one of glycerin, sodium hyaluronate, and panthenol, and the thickener is at least one of carbomer and xanthan gum.

[0020] Fourthly, the present invention provides the application of the skin care composition described in the first aspect or the skin care composition prepared by the method described in the second aspect in the preparation of skin care products.

[0021] Preferably, the skin care product is any one of toner, serum, lotion, or face cream.

[0022] Preferably, the content of the skin care composition is 0.1-10 wt%; more preferably, it is 0.5-8 wt%.

[0023] Mechanism of action of each core component in the composition: Schisandra chinensis extract is rich in lignans, which can effectively remove superoxide anions and hydroxyl radicals from the skin, improve the survival rate of keratinocytes, inhibit cell apoptosis, and reduce oxidative damage from the source; Laminaria japonica extract is rich in seaweed polysaccharides and minerals, which can moisturize and soothe skin inflammation for a long time, while activating fibroblast activity, promoting the synthesis of type I procollagen, improving skin elasticity, and reducing fine lines; Cornflower extract contains flavonoids, which can inhibit the production of MMP-1 protease, reduce collagen degradation, repair the stratum corneum, strengthen the skin barrier, and reduce damage from external stimuli; Chrysanthemum indicum extract has anti-oxidation, anti-glycation, and anti-photoaging effects, which can remove advanced glycation end products, resist UV-induced photoaging damage, and soothe sensitive redness. Four components work together to build a complete anti-aging system: palmate kelp extract promotes collagen regeneration, schisandra chinensis extract and white chrysanthemum extract can prevent damage from oxidation, glycation and photoaging in multiple dimensions, and cornflower extract can repair the skin barrier and reduce irritation, forming a closed-loop anti-aging mechanism that is suitable for the needs of sensitive skin.

[0024] Beneficial effects Compared with existing technologies, this invention has the following beneficial effects: First, the components have strong synergistic effects, with the four plant extracts complementing each other without overlapping effects, constructing a three-dimensional anti-aging system of "promoting regeneration - preventing damage - reducing irritation", and the antioxidant, anti-aging, and repair effects are far superior to those of single plant ingredients; Second, it is gentle and suitable for sensitive skin, with all components being low in irritation, and can achieve long-lasting anti-aging while repairing damaged barriers and soothing sensitive discomfort, solving the pain point of traditional anti-aging products irritating sensitive skin; Third, it has comprehensive anti-aging dimensions, taking into account anti-oxidation, anti-glycation, anti-photoaging, promoting collagen synthesis, and inhibiting collagen degradation, thus delaying skin aging from the root. Detailed Implementation

[0025] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. The described embodiments are only some preferred embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0026] Unless otherwise specified, the experimental methods used in the embodiments are conventional or common methods in the art, and the materials and reagents used are commercially available unless otherwise specified.

[0027] The raw materials used in the examples and comparative examples are described below: Schisandra chinensis extract: purchased from Draco Natural Products. Palmate kelp extract: purchased from Wuhan Beileye Biomedical Technology Co., Ltd.; Cornflower extract: purchased from Xi'an Jiatian Biotechnology Co., Ltd.; White chrysanthemum extract: purchased from Shaanxi Wanzhiyuan Biotechnology Co., Ltd.

[0028] Unless otherwise specified, all components and raw materials used in the embodiments and comparative examples of this invention are commercially available, and the same type of components and raw materials are used in each parallel experiment.

[0029] Example 1 A skincare composition for sensitive skin, comprising, by weight: 5 parts Schisandra chinensis extract, 13 parts Laminaria japonica extract, 7 parts Cornflower extract, and 6 parts Chrysanthemum indicum extract.

[0030] Example 2 A skincare composition for sensitive skin, comprising, by weight: 4 parts Schisandra chinensis extract, 12 parts Laminaria japonica extract, 6 parts Cornflower extract, and 5 parts Chrysanthemum indicum extract.

[0031] Example 3 A skincare composition for sensitive skin, comprising, by weight: 6 parts of Schisandra chinensis extract, 14 parts of Laminaria japonica extract, 8 parts of Cornflower extract, and 7 parts of Chrysanthemum indicum extract.

[0032] Example 4 A skincare composition for sensitive skin, comprising, by weight: 3 parts Schisandra chinensis extract, 15 parts Laminaria japonica extract, 5 parts Cornflower extract, and 8 parts Chrysanthemum indicum extract.

[0033] Example 5 A skincare composition for sensitive skin, comprising, by weight: 7 parts Schisandra chinensis extract, 10 parts Laminaria japonica extract, 10 parts Cornflower extract, and 3 parts Chrysanthemum indicum extract.

[0034] Example 6 A skincare composition for sensitive skin, comprising, by weight: 5 parts of Schisandra chinensis extract, 15 parts of Laminaria japonica extract, 6 parts of Cornflower extract, and 8 parts of Chrysanthemum indicum extract.

[0035] Comparative Example 1 A skincare composition for sensitive skin, comprising, by weight: 13 parts of palmate kelp extract, 7 parts of cornflower extract, and 6 parts of white chamomile extract.

[0036] Comparative Example 2 A skincare composition for sensitive skin, comprising, by weight: 5 parts Schisandra chinensis extract, 7 parts cornflower extract, and 6 parts chamomile extract.

[0037] Comparative Example 3 A skincare composition for sensitive skin, comprising, by weight: 5 parts of Schisandra chinensis extract, 13 parts of Laminaria japonica extract, and 6 parts of Chrysanthemum indicum extract.

[0038] Comparative Example 4 A skincare composition for sensitive skin, comprising, by weight: 5 parts of Schisandra chinensis extract, 13 parts of Laminaria japonica extract, and 7 parts of Cornflower extract.

[0039] Comparative Example 5 A skincare composition for sensitive skin, comprising, by weight: 5 parts blueberry fruit extract, 13 parts palmate seaweed extract, 7 parts cornflower extract, and 6 parts white chamomile flower extract.

[0040] Comparative Example 6 A skincare composition for sensitive skin, comprising, by weight: 5 parts Schisandra chinensis extract, 13 parts Spirulina extract, 7 parts Cornflower extract, and 6 parts Chrysanthemum indicum extract.

[0041] Table 1. Components and parts by weight of Examples 1-6 and Comparative Examples 1-6 Example 1 5 13 7 6 / / Example 2 4 12 6 5 / / Example 3 6 14 8 7 / / Example 4 3 15 5 8 / / Example 5 7 10 10 3 / / Example 6 5 15 6 8 / / Comparative Example 1 / 13 7 6 / / Comparative Example 2 5 / 7 6 / / Comparative Example 3 5 13 / 6 / / Comparative Example 4 5 13 7 / / / Comparative Example 5 / 13 7 6 5 / Comparative Example 6 5 / 7 6 / 13 Note: " / " indicates that the component is not present.

[0042] Performance verification was performed on Examples 1-6 and Comparative Examples 1-6.

[0043] I. Anti-inflammatory performance test 1.1 Experimental Materials RAW264.7 mouse mononuclear macrophages in the logarithmic growth phase were used as the experimental model. The cell line was purchased from Wuhan Saiss Biotechnology Co., Ltd. The tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) enzyme-linked immunosorbent assay (ELISA) kits used in the experiments were purchased from Abcam, and the testing procedures were strictly performed according to the instructions. The DMEM high-glucose medium and fetal bovine serum used for cell culture were both from Gibco, and the accompanying sterile PBS buffer, lipopolysaccharide (LPS), and other experimental reagents all met the standards for cell culture experiments.

[0044] 1.2 Experimental Methods 1.2.1 Cell Seeding and Culture RAW264.7 cells in the logarithmic growth phase with good growth and no contamination were selected, and the cell suspension density was adjusted to 1×10⁻⁶. 6Cells were seeded at a density of 1 / mL into 24-well cell culture plates for subsequent experiments. Cells were cultured in complete DMEM medium containing 10% fetal bovine serum. The seeded culture plates were then incubated continuously at 37°C and 5% CO2 for 24 hours to ensure full cell adhesion and stable growth, laying the foundation for subsequent inflammation modeling and sample intervention experiments.

[0045] 1.2.2 Construction of Inflammation Model and Group Intervention Once the cells have adhered and grown stably, gently aspirate the original culture medium from each well, maintaining aseptic technique throughout the process. Three experimental groups were set up, with six replicates in each group to ensure the reproducibility and reliability of the experimental data. The specific grouping and processing methods are as follows: Blank control group: Add 500 μL of fresh DMEM medium and 100 μL of sterile PBS buffer to each well, mix gently, and then incubate in an incubator for routine culture to eliminate the interference of the medium, buffer and other reagents on the level of cell inflammation.

[0046] LPS inflammation model group: 500 μL of fresh DMEM medium and 100 μL of LPS working solution were added to each well, mixed well, and an in vitro inflammation model of RAW264.7 cells was constructed by LPS induction.

[0047] Sample experimental group: 500 μL of fresh DMEM medium and 100 μL of LPS working solution were added to each well, and the sample solution to be tested (including the samples of each embodiment of the present invention and the comparative sample) with a concentration of 5 mg / mL was added at the same time. After thorough mixing, the samples were cultured simultaneously to explore the intervention effect of each sample on LPS-induced cell inflammation.

[0048] 1.2.3 Detection and statistical analysis of inflammatory factors After drug treatment, cells in each group were incubated at 37℃ with 5% CO2 for 24 hours. After culture, the cell supernatant from each well was collected and transferred to sterile centrifuge tubes for centrifugation to remove cell debris and impurities. The supernatant was then aspirated, and the levels of the two inflammatory factors in the cell supernatant were measured strictly according to the standard operating procedure of the Abcam TNF-α and IL-6 detection kit. Based on the measured data, the inhibition rate of inflammatory factor release for each sample was calculated, and the experimental data were statistically analyzed.

[0049] The formula for calculating the inflammatory factor inhibition rate is as follows: Inflammatory factor inhibition rate (%) = [(Average content of inflammatory factors in the model group - Average content of inflammatory factors in the experimental group) / (Average content of inflammatory factors in the model group - Average content of inflammatory factors in the blank control group)] × 100%.

[0050] Table 2 Results of Inhibition Rate of Inflammatory Factors Example 1 62.39 58.45 Example 2 56.81 53.16 Example 3 59.42 56.02 Example 4 54.74 51.29 Example 5 55.95 52.63 Example 6 55.18 52.74 Comparative Example 1 41.52 38.26 Comparative Example 2 45.33 42.71 Comparative Example 3 42.67 39.89 Comparative Example 4 37.83 34.51 Comparative Example 5 44.26 41.06 Comparative Example 6 46.54 43.78 As shown in Table 2, Example 1 exhibited inhibition rates of 62.39% and 58.45% against IL-6 and TNF-α, respectively. Examples 2-6 showed inhibition rates of 54.74%-59.42% for IL-6 and 51.29%-56.02% for TNF-α, indicating that the combinations within the specified ranges could consistently exert potent anti-inflammatory effects. In contrast, Comparative Examples 1-4, lacking a single component, showed the lowest inhibition rates of inflammatory factors at only 37.83% and 34.51%, significantly lower than the examples. Furthermore, Comparative Examples 5 and 6, after replacing Schisandra chinensis and Laminaria japonica with Bilberry Fruit Extract and Spirulina Extract, respectively, also showed a significant decrease in the inhibition rates of IL-6 and TNF-α. This fully demonstrates that the combination of Schisandra chinensis extract, Laminaria japonica extract, Cornflower extract, and Chrysanthemum indicum extract has a significant synergistic effect; each component is indispensable and cannot be easily replaced by similar raw materials. This indicates that the compound system in the examples can downregulate IL-6 and TNF-α through multiple pathways. Two key pro-inflammatory factors gently and non-irritatingly alleviate the inflammatory response of sensitive skin, effectively soothing sensitive skin.

[0051] II. Anti-aging performance verification test The DPPH free radical scavenging activity of the sensitive skin skincare compositions prepared in Examples 1-6 and Comparative Examples 1-6 of this invention was tested, and the antioxidant capacity of the samples was evaluated by in vitro antioxidant test. The specific test operation is as follows.

[0052] 0.2 mM DPPH solution: Dissolve 0.001972 g DPPH in anhydrous ethanol, bring the volume up to 25 mL with anhydrous ethanol, measure the absorbance at 517 nm and record the absorbance value as being between 0.2 and 0.8.

[0053] Sample solution: Prepare a 0.01 g / mL solution of the sample using anhydrous ethanol.

[0054] Prepare the solutions in tubes A, B, and C as follows: Tube A: 2 mL sample solution + 2 mL DPPH solution; Tube B: 2 mL DPPH solution + 2 mL anhydrous ethanol; Tube C: 2 mL anhydrous ethanol + 2 mL sample solution; Zeroing: Anhydrous ethanol; After preparation, the sample was incubated in the dark at room temperature for 30 min. The absorbance was measured at 517 nm and the absorbance value was recorded. Each sample was repeated 3 times, and the average value was taken. The DPPH free radical scavenging rate was calculated using the following formula: Y = [1 - (AC) / B] × 100%; In the formula, A, B, and C are the absorbance values ​​of tubes A, B, and C, respectively. A higher scavenging rate indicates a stronger ability of the sample to resist oxidation and scavenge free radicals in vitro.

[0055] Table 3. Record of DPPH free radical scavenging rate (%) Example 1 72.54 Example 2 68.79 Example 3 69.26 Example 4 63.71 Example 5 65.48 Example 6 64.89 Comparative Example 1 42.35 Comparative Example 2 53.47 Comparative Example 3 50.62 Comparative Example 4 49.68 Comparative Example 5 43.34 Comparative Example 6 51.81 As shown in Table 3, the DPPH free radical scavenging experimental data of Examples 1-6 ranged from 63.71% to 72.54%, indicating that the sensitive skin skincare compositions prepared in these examples all possess good antioxidant capabilities. Among them, Comparative Example 1, lacking Schisandra chinensis extract, experienced a sharp drop in scavenging rate to 42.35%, the largest decrease among all groups, confirming that Schisandra chinensis extract is the core antioxidant component of the formulation. Comparative Example 4, lacking Chrysanthemum indicum extract, Comparative Example 3, lacking Cornflower extract, and Comparative Example 2, lacking Laminaria japonica extract... The scavenging rates were 49.68%, 50.62%, and 53.47%, respectively. Meanwhile, the scavenging rates of comparative examples 5 and 6, which replaced the core components with blueberry fruit extract and spirulina extract, were only 43.34% and 51.81%, respectively, both significantly lower than those of example 1. This fully demonstrates that white chamomile extract, cornflower extract, and palmate kelp extract can assist schisandra extract in achieving multi-dimensional synergistic scavenging of free radicals, effectively reducing oxidative damage to sensitive skin. It is expected to delay aging problems such as oxidative dullness and collagen breakage, providing core antioxidant support for the anti-aging efficacy of the composition.

[0056] Application Example 1-6 and Comparative Application Example 1-6 Application Examples 1-6 and Comparative Application Examples 1-6 of the present invention provide an anti-aging serum. The composition of the anti-aging serum is shown in Table 4. Application Examples 1-6 and Comparative Application Examples 1-6 respectively contain the compositions prepared in Examples 1-6 or Comparative Examples 1-6.

[0057] The preparation method of the anti-aging serum includes the following steps: S1: Mix 1,2-hexanediol, p-hydroxyacetophenone, and 1,3-propanediol, and heat to 60°C to dissolve, to obtain the pre-prepared solution; S2: Mix glycerol, sodium hyaluronate, butylene glycol, carbomer 981, EDTA-2Na and deionized water, heat to 75°C, homogenize at 6000 rpm for 5 min until completely dissolved, then cool to 50°C, add the above pre-prepared solution at 300 rpm and stir to mix, then cool to below 45°C and add the composition provided in the example or comparative example, magnetically stir at 300 rpm for 5 min, finally add arginine to adjust the pH, stop stirring, and discharge to obtain the final product.

[0058] Table 4. Ingredients of Anti-aging Essence The compositions prepared in Examples 1-6 or Comparative Examples 1-6 5.5 glycerin 0.6 Sodium hyaluronate 0.1 Butylene glycol 4.5 Carbomer 981 0.2 EDTA-2Na 0.05 1,2-Hexanediol 0.5 p-Hydroxyacetophenone 0.5 1,3-Propanediol 2.0 Arginine 0.2 Deionized water margin Performance verification tests were conducted for the corresponding use cases 1-6.

[0059] Human patch test Test methods: In accordance with the "Cosmetic Safety Technical Specifications" (2015 edition), human patch tests were used to verify the skin irritation of this application examples 1-6. The specific test methods and the grading standards for adverse skin reactions are shown in Table 5.

[0060] Thirty volunteers, aged 20-55 years (average age 31.6 years), were recruited and signed informed consent forms for subsequent trials. First, a suitable patch applicator was selected, and a closed patch test method was used. Approximately 25 μL of the test substance was placed in the applicator, which was then applied to the inner forearm of the volunteer using hypoallergenic adhesive tape. Gently pressing the tape ensured even application to the skin. The test substance was removed after 24 hours. Skin reactions were observed at 0.5 h, 24 h, and 48 h after removing the applicator. Adverse skin reactions were recorded and are shown in Table 6.

[0061] Table 5. Grading Criteria for Adverse Skin Reactions 0 No response 1 faint erythema 2 Erythema, infiltration, and papules may be present. 3 Erythema, infiltration, edema, papules, vesicles 4 Erythema, edema, bullae Table 6. Results of adverse skin reactions

[0062] As shown in Table 6, the human patch test data indicates that the skin condition of the serum samples corresponding to Examples 1-6 was observed at three time points: 0.5h, 24h, and 48h after the removal of the patch tester. The skin reaction level of all 30 volunteers was 0 in all groups and all observation periods. No one showed any skin irritation or allergic reactions, such as weak erythema, infiltrated papules, edema, or blisters. There was no immediate contact irritation or delayed sensitization risk. At the same time, all six formulations covering the entire ratio range of the composition of this invention showed consistent high safety, which fully demonstrates that the plant compound composition has extremely low irritation, good skin tolerance, and is suitable for long-term use on sensitive skin with a fragile skin barrier.

[0063] II. Human Anti-aging Tests Subjects were selected in accordance with the requirements of the "Cosmetic Safety Technical Specifications" (2015 edition), and 60 volunteers aged 23-50 with dry and sensitive skin were recruited. Inclusion criteria: lactic acid stinging score >3 points, facial stratum corneum moisture content 20 CU-50 CU; Exclusion criteria: use of retinol, high concentration of fruit acid, or hormonal products within the past 30 days, presence of facial skin diseases, allergic dermatitis, pregnant or breastfeeding women, and those who have undergone cosmetic procedures within the past month.

[0064] The qualified volunteers were randomly divided into 12 groups of 5 people each, corresponding to Application Examples 1-6 and Comparative Application Examples 1-6 respectively.

[0065] The entire experiment was conducted in a constant temperature and humidity testing room, with environmental parameters controlled at 21±1℃ and 50±10% relative humidity. Subjects sat quietly for 30 minutes after entering the testing room until their skin condition stabilized before the indicators were measured. Each day after cleansing, volunteers in each group applied 1 mL of their corresponding group's serum evenly to their entire face and gently massaged it for 5 minutes until fully absorbed. The testing instrument used was a Primos CR 5.8E 3D skin analyzer to acquire images of the crow's feet area and analyze the improvement in wrinkle area. Uniform measurements were taken at three time points: before sample use (baseline), after 7 days of continuous use, and after 28 days of continuous use. The wrinkle area improvement rate (%) was calculated, and the results are shown in Table 7. Calculation formula: Wrinkle area improvement rate (%) = (wrinkle area...) / (wrinkle area...) 使用前 -Wrinkle area 使用后 ) / Wrinkle area 使用前 ×100%.

[0066] Table 7. Record of Wrinkle Area Improvement Rate (%) Application Example 1 15.35 22.92 Application Example 2 13.28 20.53 Application Example 3 13.14 20.67 Application Example 4 12.02 18.81 Application Example 5 11.17 19.16 Application Example 6 12.91 18.62 Comparative Application Example 1 4.65 7.28 Comparative Application Example 2 6.91 11.14 Comparative Application Example 3 6.82 8.72 Comparative Application Example 4 6.58 9.17 Comparative Application Example 5 6.75 9.55 Comparative Application Example 6 6.94 11.26 As shown in Table 7, the wrinkle improvement test data of human body shows that Application Example 1, which uses the complete four-component compound, has the best wrinkle improvement effect, with an improvement rate of 15.35% after 7 days and 22.92% after 28 days. The wrinkle improvement rates of the other Application Examples 2-6 range from 11.17% to 13.28% after 7 days and from 18.62% to 20.67% after 28 days. In contrast, the comparative applications 1-4, which lack any active ingredient, and the comparative applications 5-6, which use blueberry fruit extract and spirulina to replace the core ingredients, have wrinkle improvement rates of only 4.65% to 6.94% after 7 days and only 7.28% to 11.26% after 28 days, which are significantly lower than those of Application Example 1. Compared to the worst wrinkle improvement rate in application example 1 (corresponding to application examples 1-4), this result is consistent with the DPPH free radical scavenging rate results in Table 3, proving that Schisandra chinensis extract is the core anti-wrinkle component. Furthermore, by comparing application examples 1-6 with application example 1, it can be seen that the four components (Schisandra chinensis extract, Chrysanthemum indicum extract, Cornus officinalis extract, and Laminaria japonica extract) may work together through multiple pathways such as anti-oxidation, inhibiting collagen degradation, promoting collagen regeneration, and soothing inflammation, which can gradually reduce fine lines on sensitive skin, improve skin firmness, and achieve gentle and long-lasting anti-aging.

[0067] The preferred embodiments of the present invention disclosed above are merely illustrative of the invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the invention to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of the invention, thereby enabling those skilled in the art to better understand and utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. A skincare composition for sensitive skin with antioxidant and anti-aging effects, characterized in that, By weight, it includes: 3-7 parts of Schisandra chinensis extract, 10-15 parts of Laminaria japonica extract, 5-10 parts of Cornflower extract, and 3-8 parts of Chrysanthemum indicum extract.

2. The skincare composition according to claim 1, characterized in that, By weight, it includes: 4-6 parts of Schisandra chinensis extract, 12-14 parts of Laminaria japonica extract, 6-8 parts of Cornflower extract, and 5-7 parts of Chrysanthemum indicum extract.

3. A method for preparing the skincare composition as described in claim 1 or 2, characterized in that, The extracts of Schisandra chinensis, Laminaria japonica, Cornflower, and Chrysanthemum indicum are mixed evenly according to their respective weight proportions to obtain the final product.

4. A skincare product, characterized in that, The product contains the skincare composition as described in claim 1 or 2, wherein the content of the skincare composition is 0.1-10 wt%.

5. The skincare product according to claim 4, characterized in that, The content of the skin care composition is 0.5-8 wt%.

6. The skincare product according to claim 4, characterized in that, The skincare product also contains cosmetically acceptable excipients, including one or more of moisturizers, thickeners, emollients, antioxidants, and deionized water.

7. The skincare product according to claim 4, characterized in that, The humectant is at least one of glycerin, sodium hyaluronate, and panthenol, and the thickener is at least one of carbomer and xanthan gum.

8. The use of the skin care composition according to any one of claims 1-2 or the skin care composition prepared by the method of claim 3 in the preparation of skin care products.

9. The application according to claim 8, characterized in that, The skincare product can be any one of toner, serum, lotion, or face cream.

10. The application according to claim 9, characterized in that, The content of the skin care composition is 0.1-10 wt%.

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