A multi-targeted clarifying and repairing composition for adolescent acne marks and its use

Abstract

The present application belongs to the technical field of cosmetics, and particularly relates to a multi-target point purifying and repairing composition for acne marks and darkening of teenagers and application thereof. In order to solve the problems of single target point, high irritation and weak targeting of existing repairing products, the composition is compounded by four functional components, i.e. inflammation mediator melanin production blocking component, anti-sebum oxidation darkening component, melanin production-transportation-autophagy regulation component and mild keratinocyte renewal and barrier reconstruction component, in a limited ratio. The specific components synergistically act to achieve multi-dimensional repair of inflammation melanin production signal blocking, melanin whole-link regulation, sebum oxidation darkening improvement and skin barrier reconstruction. The present application is suitable for the fragile skin of teenagers, is mild and non-irritating, can effectively improve the problems of acne mark darkening, red mark blackening, uneven skin color, sebum darkening and the like, and has a comprehensive repairing effect, and has a good application prospect in the field of functional skin care for teenagers.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, and in particular relates to a multi-target purifying and repairing composition for acne scars and dullness in teenagers and its application. Background Technology

[0002] Hormonal changes during adolescence lead to increased sebaceous gland activity and excessive sebum secretion, making the hair follicle sebaceous gland ducts prone to blockage and triggering acne. After acne subsides, it is often accompanied by post-inflammatory redness, dark marks, pigmentation, and uneven skin tone, seriously affecting the mental health and quality of life of adolescents.

[0003] Currently, cosmetics and skincare compositions on the market targeting acne scars and dull skin tone have developed into several mature technological approaches, with their core efficacy mechanisms mainly falling into five categories: 1. Technology to inhibit melanin production: Most products focus on inhibiting tyrosinase (TYR) activity, and commonly use ingredients such as α-arbutin, 377 (phenylethyl resorcinol), kojic acid, and vitamin C derivatives to lighten pigmentation by reducing melanin synthesis; 2. Technologies that promote keratin renewal and metabolism: Some products use acidic ingredients such as fruit acids (AHA), salicylic acid (BHA), and mandelic acid, which accelerate the metabolism of the stratum corneum and promote the shedding of melanin-containing keratinocytes, thereby improving acne scars and uneven skin tone; 3. Anti-inflammatory and soothing repair technology: Existing technologies widely use plant ingredients such as asiaticoside, scutellaria baicalensis extract, tea tree oil, and chamomile extract, which aim to reduce acne inflammation, relieve redness, and help fade post-inflammatory hyperpigmentation; 4. Antioxidant and sebum-related dullness-improving technologies: For cases of excessive sebum secretion, some products use antioxidant ingredients such as vitamin E derivatives and polyphenolic compounds to reduce the impact of lipid peroxidation on skin tone; 5. Other integrated technologies: In recent years, multi-effect compositions that combine anti-inflammatory, whitening, and barrier repair ingredients have emerged, as well as some solutions that utilize nanodelivery systems or promote cell metabolism to enhance the permeability and efficacy of active ingredients.

[0004] While existing technologies can improve mild acne scars and dull skin to some extent, they still have many core technological shortcomings when it comes to the specific physiological characteristics of oily and acne-prone skin in teenagers. These shortcomings prevent them from meeting the core needs of teenagers for safe, gentle, effective, and long-lasting repair of acne scars and dullness. 1. Single mechanism of action, making it difficult to achieve synergistic intervention across multiple stages: Most products only focus on inhibiting tyrosinase activity, or only on the melanin production stage, or promote keratin exfoliation. They fail to simultaneously target multiple key stages such as post-inflammatory melanin-promoting signals (IL-1α, TNF-α, PGE2, etc.), melanosome transport, autophagic degradation of existing melanosomes, sebum oxidation and darkening, and barrier damage. This results in limited improvement effects on post-inflammatory red marks turning into black marks, stubborn acne marks, and sebum oxidation-induced darkening. 2. Ignoring the root causes of inflammation and sebum oxidation: Current technologies pay little attention to the melanin-promoting cascade response induced by acne inflammation, as well as the lipid peroxidation, glycation, and carbonylation-induced darkening caused by vigorous sebum secretion in adolescents. It is difficult to block the initiation of pigmentation and oxidative stress damage from the source. 3. Highly irritating and lacking in safety: Products that rely on high concentrations of acids (fruit acids, salicylic acid, etc.) or potent whitening ingredients are likely to cause stinging, dryness, redness, and damage to the barrier function of the fragile skin of teenagers. They may even aggravate post-inflammatory hyperpigmentation and have poor long-term use compliance. 4. Insufficient ability to remove stubborn acne scars: For existing melanosomes and lipofuscin accumulation, current technology mainly relies on passive metabolic renewal and lacks effective means to promote cell autophagy degradation, resulting in poor improvement of old and stubborn acne scars and darkening. 5. Lack of specificity and target population: Most existing products are general solutions for fading dark spots or removing acne scars, without fully considering the special physiological characteristics of teenagers with oily and acne-prone skin, such as "excessive sebum production, fragile skin barrier, and recurring inflammation." As a result, it is difficult to achieve effective cleansing and repair while maintaining good gentleness and comfort.

[0005] In summary, existing technologies for repairing acne scars and dullness generally suffer from several drawbacks, including limited targeting, lack of source control, high skin irritation, insufficient ability to remove stubborn pigmentation, and poor targeting of adolescents. These limitations make it difficult to balance safety, gentleness, and efficacy, and fail to accurately address the challenges of repairing acne scars and dullness in oily, acne-prone skin of teenagers. Therefore, developing a low-irritation, multi-target, and end-to-end synergistic repair composition for acne scars and dullness, suitable for adolescent skin, is a pressing technical problem that needs to be solved by those skilled in the art. Summary of the Invention

[0006] The purpose of this invention is to overcome the shortcomings of the prior art and provide a multi-target purifying and repairing composition for acne scars and dullness in teenagers, and its application. This composition overcomes the problems of existing technologies, such as single-step action, strong irritation, and insufficient targeting. It provides synergistic intervention from multiple dimensions, including blocking post-inflammatory melanin-promoting signals, regulating melanin production, inhibiting melanosome transport, autophagic degradation of existing melanosomes, improving sebum oxidation and dullness, and rebuilding barrier function. This achieves comprehensive repair of acne scars and dullness in teenagers, redness turning into dark marks, uneven skin tone, sebum oxidation and dullness, and a weakened skin barrier.

[0007] To achieve the above objectives, the technical solution adopted by the present invention includes: In a first aspect, the present invention provides a multi-target purifying and repairing composition for acne scars and dullness in teenagers, the composition comprising the following components in parts by weight: 1-10 parts of inflammatory mediator melanin-inhibiting component, 0.2-9 parts of anti-sebum oxidation and dullness component, 0.45-9 parts of melanin production-transport-autophagy regulating component, and 0.5-8 parts of gentle keratin renewal and barrier reconstruction component.

[0008] The composition of this invention, through the precise synergy of its four functional components, can achieve a "full-chain, multi-target" intervention on acne scars and darkening in adolescents. Specifically, the inflammatory mediator melanin-promoting blocking component blocks melanin-promoting signals induced by inflammatory mediators such as IL-1α, TNF-α, and PGE2 at the source of inflammation, while simultaneously soothing TRPV1 / CA. 2+ This mediated neurosensitivity response reduces the risk of post-acne redness turning into dark marks and dullness, reduces stinging and redness, and improves user comfort and compliance for teenagers with sensitive acne-prone skin. Preferably, the inflammatory mediator melanin-inhibiting component includes Ophiopogon japonicus root extract and / or rhamnose.

[0009] The anti-sebum oxidation dullness component is designed to target yellowish-brown dullness and cloudy skin caused by excessive sebum production, sebum oxidation, lipid peroxidation, glycation, and carbonylation in adolescents. It scavenges free radicals, inhibits oxidative stress, and significantly improves acne scars and overall sebum oxidation-related dullness. Preferably, the anti-sebum oxidation dullness component includes milk thistle extract and / or yeast / Acetobacter xylinum / black tea fermentation products.

[0010] The melanin production-transportation-autophagy regulating component is used to inhibit abnormal melanin production and epigenetic regulation after inflammation at multiple targets, reduce melanosome transport and keratinocyte uptake, and simultaneously promote the autophagic degradation of existing melanosomes and lipofuscin, thus fading stubborn acne scars and dark spots from the entire "production-transportation-clearance" chain. Preferably, the melanin production inhibiting component includes hexapeptide-2; the melanosome transport reducing component includes hydrolyzed yeast protein; and the melanosome autophagy degrading component includes hydrolyzed plant protein.

[0011] The gentle keratin renewal and barrier rebuilding component is designed to promote KLK7-mediated keratin renewal without relying on strong acid exfoliation, while simultaneously enhancing the expression of barrier-related proteins to achieve "cleansing old skin and promoting new skin." It strengthens barrier stability while fading acne scars and dark spots, making it suitable for long-term use by teenagers with fragile acne-prone skin. Preferably, the gentle keratin renewal and barrier rebuilding component includes Ulva lactuca extract and / or Bacillus fermentation products.

[0012] The four functional components described above work in sequence to form a complete intervention loop: "blocking activation—signal regulation—generation inhibition—transport reduction—degradation and clearance—oxidative protection—barrier strengthening." Each link is mutually supportive and indispensable, collectively giving the composition comprehensive advantages in efficacy, safety, and user experience, providing a more scientific and gentler systemic solution for acne scars and dullness in teenagers.

[0013] Preferably, the mass ratio of hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein in the melanin production-transport-autophagy regulatory component is (0.5-2):1:1.

[0014] More preferably, the mass ratio of hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein is 1:1:1.

[0015] Hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein are precisely matched in equal proportions to ensure that abnormal melanin production upstream is fully inhibited, midstream melanosome transport to the epidermis is effectively intercepted, and downstream lysosomes are simultaneously given sufficient autophagic degradation flux. This avoids the chain break caused by excessive or insufficient strength in one link, maximizes the fading effect on stubborn acne marks, and avoids the risk of barrier imbalance caused by excessive intervention in a single pathway to fragile acne-prone skin.

[0016] Preferably, the composition comprises the following components in parts by weight: 3-8 parts of Ophiopogon japonicus root extract, 5-9 parts of yeast / Acetobacter xylinum / black tea fermentation product, 1-3 parts of hydrolyzed plant protein, 1-3 parts of hexapeptide-2, 1-3 parts of hydrolyzed yeast protein, and 2-5 parts of Bacillus fermentation product.

[0017] More preferably, the composition comprises the following components in parts by weight: 5 parts of Ophiopogon japonicus root extract, 7 parts of yeast / Acetobacter xylinum / black tea fermentation product, 2 parts of hydrolyzed plant protein, 2 parts of hexapeptide-2, 2 parts of hydrolyzed yeast protein, and 3 parts of Bacillus fermentation product.

[0018] Preferably, the composition comprises the following components in parts by weight: 1-3 parts rhamnose, 1-3 parts milk thistle extract, 0.8-2.5 parts hydrolyzed plant protein, 0.8-2.5 parts hexapeptide-2, 0.8-2.5 parts hydrolyzed yeast protein, and 1.5-4 parts Ulva extract.

[0019] More preferably, the composition comprises the following components in parts by weight: 3 parts rhamnose, 2 parts milk thistle extract, 1.5 parts hydrolyzed plant protein, 1.5 parts hexapeptide-2, 1.5 parts hydrolyzed yeast protein, and 2.5 parts Ulva extract.

[0020] Experimental research revealed that, compared to conventional compound systems, the combination of the two specific formulas mentioned above can achieve superior effects in fading acne scars and repairing the skin barrier. This specific combination is not a simple addition of components, but rather a precise control of the proportions of each active ingredient to avoid antagonistic interactions between components, maximizing the release of active efficacy and achieving a more ideal synergistic effect. This provides a key and feasible optimized formula option for skincare compositions that combine acne scar fading and skin barrier repair.

[0021] Secondly, the present invention provides the use of the described composition in the preparation of cosmetics.

[0022] Preferably, the cosmetic is a cosmetic that has the effects of improving dullness caused by acne scars in teenagers, post-inflammatory hyperpigmentation, dullness caused by sebum oxidation, uneven skin tone, and / or repairing the skin barrier.

[0023] Preferably, the dosage form of the cosmetic includes at least one of the following: aqueous solution, lotion, cream, serum, mask, and cleanser.

[0024] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) Synergistic effect of multiple targets, full-link intervention in the formation and development of acne scars: The composition of the present invention acts simultaneously on multiple key links such as blocking post-inflammatory melanin-promoting signals (IL-1α, TNF-α, PGE2, etc.), regulating melanin production, inhibiting melanosome transport, autophagy degradation of existing melanosomes, sebum oxidation and glycation / carbonylation darkening, gentle keratin renewal and barrier reconstruction, etc., to achieve full-link synergistic repair from "source blocking - production inhibition - transport reduction - degradation clearance - oxidative protection - barrier strengthening", overcoming the limitations of existing technologies with single mechanism of action and only targeting a certain link, and improving acne scar darkening more comprehensively and efficiently.

[0025] (2) Highly specific for teenagers with oily and acne-prone skin: This invention fully considers the characteristics of teenagers with vigorous sebum secretion, fragile barrier and repeated inflammation, and focuses on solving the problem of dullness and turbidity caused by sebum oxidation. At the same time, it takes into account the comfort of sensitive skin in the process of fading marks. The target population is significantly better than existing general spot fading or acne mark removal products.

[0026] (3) Low irritation, high safety and good user compliance: This invention does not rely on high concentrations of acid peeling or strong irritating whitening ingredients. It achieves a balance between efficacy and gentleness through the combination of plant extracts, soothing peptides and mild active ingredients, effectively reducing adverse reactions such as stinging, dryness and redness, and is suitable for long-term daily use by teenagers.

[0027] (4) It has outstanding effects on improving stubborn acne marks and old pigmentation: by promoting the autophagy metabolism pathway of melanosomes and lipofuscin, it effectively removes stubborn acne marks and dark spots that have been formed, which solves the shortcomings of existing technologies that mainly rely on passive keratin renewal and are difficult to deal with “old” pigmentation.

[0028] (5) Synergistic effect of ingredients and excellent overall performance: The scientific combination of the four functional components of this invention produces a synergistic effect, which improves the stability and skin compatibility of the composition while achieving efficient cleansing and repair, providing a safer and more effective solution for acne scars and dull skin in teenagers. Attached Figure Description

[0029] Figure 1 The images show the appearance of the compositions obtained in Examples 3 and 10, respectively. Figure 2 Comparison of facial effects on subjects before and after 28 days of using the composition described in Example 3; Figure 3 Comparison of facial effects on subjects before and after 28 days of using the composition described in Example 10. Detailed Implementation

[0030] To better illustrate the objectives, technical solutions, and advantages of this invention, the invention will be further described below with reference to specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0031] The sources of the raw materials mentioned in the following embodiments and comparative examples are shown in Table 1: Table 1 Examples 1-7 Examples 1-7 provide a multi-target purifying and repairing composition for acne scars and dullness in teenagers, the formulation of which is shown in Table 2 (total weight parts: 100 parts). The composition is obtained by mixing each component with water until homogeneous.

[0032] Table 2 Formulation table (parts by weight) of the compositions described in Examples 1-7 Examples 8-12 Examples 8-12 provide a multi-target purifying and repairing composition for acne scars and dullness in teenagers, the formulation of which is shown in Table 3 (total weight parts: 100 parts). The composition is obtained by mixing each component with water until homogeneous.

[0033] Table 3 Formulation table (parts by weight) of the compositions described in Examples 8-12 Comparative Examples 1-8 Comparative Examples 1-8 provide a composition with a formulation shown in Table 4 (total parts by weight 100 parts). The composition is obtained by mixing each component with water until homogeneous.

[0034] Table 4 Formulation table (parts by weight) of the compositions described in Comparative Examples 1-8 Comparative Example 9 This comparative example provides a composition that differs from Example 3 only in that an equal amount of nicotinamide is used to replace the hydrolyzed yeast protein, while the remaining components and amounts are the same as in Example 3.

[0035] Comparative Example 10 This comparative example provides a composition that differs from Example 10 only in that an equal amount of ergothioneine is used to replace milk thistle extract, while the remaining components and amounts are the same as in Example 10.

[0036] Comparative Example 11 This comparative example provides a composition that differs from Example 10 only in that an equal amount of grapefruit fruit extract is used to replace the sea lettuce extract, while the remaining components and amounts are the same as in Example 10.

[0037] Test Example 1 Using the compositions described in Examples 1-12 and Comparative Examples 1-11 as test samples, a closed skin patch test was conducted on human skin to evaluate the irritation of the samples to human skin. The specific test method is as follows: Thirty subjects meeting the inclusion criteria for human patch testing were selected and tested with the compositions described in Examples 1-12 and Comparative Examples 1-11, respectively. Qualified patch testing equipment was used, and the closed patch testing method was employed. 0.025 mL of test sample was accurately measured and evenly placed in the patch applicator. The applicator was then applied to the subject's back skin using hypoallergenic adhesive tape, ensuring a tight seal between the applicator and skin, free of air bubbles, to prevent leakage of the test substance. After 24 hours, the test substance and patch applicator were carefully removed. Skin reactions in the patch area on the subject's back were observed at three time points: 0.5 h, 24 h, and 48 h after removal. The skin reaction grading standards specified in the "Cosmetic Safety Technical Specifications" (2015 edition) were strictly followed, and detailed records of skin reactions at each time point were kept, including no reaction, erythema, papules, vesicles, etc., to ensure the authenticity and completeness of the experimental data.

[0038] Tests showed that after 24 hours and 48 hours of application of the test product of this invention, no skin redness or erythema or other allergic reactions were observed in the subjects. This indicates that the composition of this invention is non-irritating and non-sensitizing to human skin, mild and safe, with excellent human compatibility, meets the safety standards for cosmetic use, and can be safely applied to human skin.

[0039] Test Example 2 Using the compositions described in Examples 1-12 and Comparative Examples 1-11 as test samples, human trials were conducted to verify the multi-target repair efficacy of the compositions on acne-scarred skin in adolescents. The specific test methods are as follows: Two hundred and thirty adolescent subjects aged 18-25 years with significant acne scars (including red and black acne scars) were randomly divided into 23 groups of 10 subjects each. The subjects in each group used the compositions described in Examples 1-12 and Comparative Examples 1-11, respectively. After cleansing their faces morning and evening, each group applied 2 ml of the corresponding composition evenly to their face, covering all acne scar areas, and gently massaged until fully absorbed. This was continued for 28 days. Follow-up indicators were measured before the start of the trial (Day 0, D0) and on Day 28 (D28).

[0040] On the day of their visit, participants cleansed their faces with a standardized facial cleanser and sat quietly for at least 20 minutes in a laboratory at 21±1℃ and 50±10% RH, without drinking water or beverages, remaining relaxed. Instruments were used to quantify and photograph changes in different types of acne scars, including VISIA-CR to measure a* values ​​and Mexamter MX18 to measure heme (EI) and melanin (MI) content. Changes in a* and EI values ​​represent the degree of improvement in red acne scars; lower values ​​indicate more significant fading. Changes in MI values ​​represent the degree of improvement in black acne scars; lower values ​​indicate more significant fading. The Tewameter™ 300 measured transepidermal water loss (TEWL) values, reflecting the amount of water lost through the epidermis per unit time and per unit cross-sectional area. A higher TEWL value indicates greater skin water loss and a weaker skin barrier function; conversely, a lower TEWL value indicates less skin water loss and a more robust skin barrier function. When testing the above indicators, each test area was measured three times and the average value was taken. Finally, the average value of the data in each group was taken as the final test result, as shown in Table 5-6.

[0041] The changes in acne scars are represented by the rate of change of each value, calculated as follows: Rate of change = 100% × (X) D28 -X D0 ) / X D0 TEWL value change rate = 100% × (TEWL value) D28-TEWL value D0 ) / TEWL value D0 Table 5 Results of the light-staining efficacy test Table 6 Results of Repair Efficacy Tests Tables 5-6 show that the composition prepared using the four core functional components of this invention—the inflammatory mediator melanin-inhibiting component, the anti-sebum oxidation darkening component, the melanin production-transport-autophagy regulating component, and the gentle keratin renewal and barrier reconstruction component—possesses excellent comprehensive skin repair efficacy. Experimental data shows that the composition can effectively reduce the a*, EI, and MI values ​​of the subjects' facial skin, exhibiting good inhibitory and fading effects on facial acne scar formation and pigmentation; simultaneously, it can reduce the skin's TEWL value, effectively reducing skin moisture loss and repairing damaged skin barriers. Based on these dual effects, the composition of this invention can specifically address multiple problems commonly found in adolescent skin, such as acne scar darkening, redness and oxidative darkening, uneven skin tone, yellowing and darkening due to sebum oxidation, and fragile and sensitive skin barriers, achieving multi-dimensional comprehensive repair. Among them, the specific formulations in Examples 3 and 10 showed the best performance in acne scar fading efficiency, improvement in pigment uniformity, and skin barrier repair strength.

[0042] In contrast, in Examples 1-3 and 6, the absence of any one of the four functional components significantly reduced the acne scar fading effect and skin barrier repair ability of the compositions compared to the examples, resulting in a substantial decrease in repair efficacy. This indicates that the four core functional components of this invention are not simply additive, but rather have a synergistic relationship. Each component performs its own function, works synergistically with the others, and is indispensable. The absence of any one component will disrupt the overall efficacy balance, leading to a significant failure of the composition's comprehensive repair performance.

[0043] In Comparative Examples 4-5, when the specific melanin-regulating component of this invention was selected as a single ingredient from hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein, respectively, the overall repair efficacy of the composition also showed a significant decline. The effects of fading acne scars, regulating pigmentation, and repairing the skin barrier were all inferior to those in the examples. This indicates that hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein alone cannot replace the function of the specific melanin production-transport-autophagy regulating component of this invention. The combination of the three is the key specific ingredient for achieving highly efficient melanin inhibition and scar fading.

[0044] In Comparative Examples 7-8, the types of raw materials for the four core functional components remained unchanged. However, when the proportions of the components deviated from the preferred range of this invention, compared to the examples, the composition with the unbalanced proportions showed a certain degree of decrease in both blemish-fading and barrier-repairing effects. This indicates that the preferred proportion range of the four functional components defined in this invention is a core condition for ensuring the optimal efficacy of the composition. A suitable proportion can maximize the synergistic effect of each component, while an imbalanced proportion will directly weaken the synergistic effect between components and reduce the overall skincare performance of the product.

[0045] In Comparative Examples 9-11, when general skincare ingredients with similar efficacy were used to replace the specific components in this invention, the overall repair efficacy of the compositions all decreased to some extent. This further demonstrates that the four core functional components screened in this invention have high compatibility, and conventional ingredients with similar efficacy cannot replicate the skincare effects of its formulation system.

[0046] Therefore, the above results fully demonstrate that the four specific core functional components precisely screened in this invention can exert a synergistic effect when combined within a limited ratio range. Through the synergistic effect of multiple pathways such as inflammation blocking, anti-oxidation, melanin regulation, keratin repair, and barrier reconstruction, it can effectively solve skin problems such as acne scars and dullness and damaged skin barrier in teenagers, and has a better and more stable comprehensive skin care and repair effect.

[0047] Finally, it should be noted that the above embodiments are used to illustrate the technical solutions of the present invention and not to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A multi-target purifying and repairing composition for acne scars and dullness in teenagers, characterized in that, The composition comprises the following components in parts by weight: 1-10 parts of inflammatory mediator melanin-inhibiting component, 0.2-9 parts of anti-sebum oxidation and darkening component, 0.45-9 parts of melanin production-transport-autophagy regulating component, and 0.5-8 parts of gentle keratin renewal and barrier reconstruction component; The inflammatory mediator melanin-blocking component includes Ophiopogon japonicus root extract and / or rhamnose; The anti-sebum-oxidative dullness component includes milk thistle extract and / or yeast / Acetobacter xylinum / black tea fermentation product; The melanin production-transport-autophagy regulatory component includes hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein; The gentle keratin renewal and barrier rebuilding components include Ulva lactuca extract and / or Bacillus fermentation products.

2. The composition according to claim 1, characterized in that, The mass ratio of hexapeptide-2, hydrolyzed yeast protein, and hydrolyzed plant protein in the melanin production-transport-autophagy regulatory component is (0.5-2):1:

1.

3. The composition according to claim 1, characterized in that, The composition comprises the following components in parts by weight: 3-8 parts of Ophiopogon japonicus root extract, 5-9 parts of yeast / Acetobacter xylinum / black tea fermentation product, 1-3 parts of hydrolyzed plant protein, 1-3 parts of hexapeptide-2, 1-3 parts of hydrolyzed yeast protein, and 2-5 parts of Bacillus fermentation product.

4. The composition according to claim 3, characterized in that, The composition comprises the following components in parts by weight: 5 parts of Ophiopogon japonicus root extract, 7 parts of yeast / Acetobacter xylinum / black tea fermentation product, 2 parts of hydrolyzed plant protein, 2 parts of hexapeptide-2, 2 parts of hydrolyzed yeast protein, and 3 parts of Bacillus fermentation product.

5. The composition according to claim 1, characterized in that, The composition comprises the following components in parts by weight: 1-3 parts rhamnose, 1-3 parts milk thistle extract, 0.8-2.5 parts hydrolyzed plant protein, 0.8-2.5 parts hexapeptide-2, 0.8-2.5 parts hydrolyzed yeast protein, and 1.5-4 parts Ulva extract.

6. The composition according to claim 5, characterized in that, The composition comprises the following components in parts by weight: 3 parts rhamnose, 2 parts milk thistle extract, 1.5 parts hydrolyzed plant protein, 1.5 parts hexapeptide-2, 1.5 parts hydrolyzed yeast protein, and 2.5 parts Ulva extract.

7. The use of the composition according to any one of claims 1-6 in the preparation of cosmetics.

8. The application as described in claim 7, characterized in that, The cosmetics mentioned are cosmetics that have the effects of improving acne scars and dullness in teenagers, post-inflammatory hyperpigmentation, sebum oxidation and dullness, uneven skin tone and / or skin barrier repair.

9. The application as described in claim 7, characterized in that, The dosage forms of the cosmetics include at least one of the following: aqueous solution, lotion, cream, serum, mask, and cleanser.

Images