A skin rejuvenating moisturizing composition and method of making and using same
Patent Information
- Application Number
- CN202611425206.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-09-15
- Publication Date
- 2026-10-23
AI Technical Summary
现阶段消费者应对这类肌肤问题的常规手段，大多依靠日常涂抹护肤产品进行表层补水锁水，部分人群会选择使用含酸类、酶类成分的焕肤产品加速老废角质脱落，改善皮肤粗糙暗沉状态，也有一部分消费者会搭配面膜进行短时密集补水护理，但多数普通护理手段仅能实现短暂改善，难以同时兼顾角质调理焕新与屏障长效保湿修护，容易出现改善后很快反弹，甚至护理不当进一步加重皮肤损伤的情况
本发明提供一种焕肤保湿组合物，由蜂蜜提取物、波尔多树叶提取物、绣球菌提取物、水解咖啡黄葵提取物、棕榈酰五肽-4与柠檬酸钠在特定配比范围内科学复配得到，其中，蜂蜜提取物含有天然多糖、氨基酸及酚类物质等活性成分，具备吸湿保湿、修护角质层和舒缓肌肤的潜力；波尔多树叶提取物中富含多酚和黄酮类化合物，能够通过减少氧化应激反应，帮助改善肤色不均，达到提亮肌肤的效果；绣球菌提取物确实含有高活性β-葡聚糖，具备优异的深层保湿与透皮修护能力，可渗透肌底提升肌肤自身持水能力，改善肌肤缺水干瘪状态，同时舒缓肌肤应激损伤，增强肌肤耐受度；水解咖啡黄葵提取物含有植物黏液质和植物甾醇等活性成分，能帮助皮肤锁水，维持水分平衡，改善干燥状态，使皮肤水润透亮；棕榈酰五肽-4具备激活皮肤成纤维细胞活性、促进胶原蛋白合成的作用，能够增强肌肤紧致感和光泽度，改善肤色；柠檬酸钠作为配方适配助剂，优化各活性成分的配伍环境，提升整体配方稳定性与活性留存率，保障各成分功效稳定释放，同时辅助提升肌肤水润通透质感；各成分协同增效，能够发挥良好的焕肤、保湿效果。
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Abstract
Description
Technical Field
[0001] This invention belongs to the field of cosmetic technology, and relates to a skin-renewing and moisturizing composition, its preparation method, and its application. Background Technology
[0002] Due to external factors such as air pollution and ultraviolet radiation, as well as internal factors such as the gradual decline in the skin's ability to synthesize lipids like ceramides and cholesterol with age, and a slowdown in keratinocyte metabolism, more and more people are facing skin problems such as dryness, roughness, dullness, disordered keratinocyte metabolism, and a fragile skin barrier leading to redness and stinging. Consequently, the demand for skincare products is increasing. Currently, consumers mostly rely on daily application of skincare products for surface hydration and moisture retention. Some choose to use exfoliating products containing acids or enzymes to accelerate the shedding of dead skin cells and improve roughness and dullness. Others combine these methods with face masks for short-term intensive hydration. However, most common skincare methods only provide temporary improvement and cannot simultaneously address both keratinocyte regeneration and long-term skin barrier repair and hydration. This often results in rapid rebound after initial improvement, or even further skin damage if improper care is not taken. Therefore, there is still significant room for improvement in exfoliating and moisturizing products. Summary of the Invention
[0003] The purpose of this invention is to overcome the shortcomings of the prior art by providing a skin-renewing and moisturizing composition, its preparation method, and its application.
[0004] The objective of this invention can be achieved through the following technical solutions: In a first aspect, the present invention provides a skin-renewing and moisturizing composition, wherein the raw materials of the skin-renewing and moisturizing composition, by weight, include 0.4-1 parts of honey extract, 0.01-0.3 parts of Bordeaux leaf extract, 0.05-0.15 parts of Hydrangea macrophylla extract, 0.1-1 parts of hydrolyzed Okra extract, 0.05-0.3 parts of palmitoyl pentapeptide-4, and 0.1-0.3 parts of sodium citrate.
[0005] Furthermore, the raw materials of the skin-renewing and moisturizing composition, by weight, include 0.5-0.7 parts honey extract, 0.1-0.2 parts Bordeaux leaf extract, 0.08-0.12 parts Hydrangea macrophylla extract, 0.4-0.8 parts hydrolyzed Okra extract, 0.15-0.25 parts palmitoyl pentapeptide-4, and 0.15-0.25 parts sodium citrate.
[0006] In a second aspect, the present invention provides a method for preparing the skin-renewing and moisturizing composition described in the first aspect, comprising the following steps: Mix the ingredients evenly according to the formula to obtain the skin-renewing and moisturizing composition.
[0007] Thirdly, the present invention provides the application of the skin-renewing and moisturizing composition described in the first aspect in the preparation of cosmetics, wherein the cosmetics include toners, lotions, creams, masks or freeze-dried powders.
[0008] Furthermore, the amount of the skin-renewing and moisturizing composition added to the cosmetic is 0.1wt%-1wt%.
[0009] Fourthly, the present invention provides a moisturizing cream comprising the skin-renewing and moisturizing composition described in the first aspect.
[0010] Furthermore, the moisturizing cream also contains excipients acceptable in the cosmetics industry.
[0011] Furthermore, the excipients acceptable in the cosmetics field include solvents, humectants, thickeners, emulsifiers, skin moisturizers, antioxidants, chelating agents, pH adjusters, preservatives, fragrances, and colorants.
[0012] The beneficial effects of this invention are: This invention provides a skin-renewing and moisturizing composition, scientifically formulated from honey extract, Bordeaux leaf extract, Hydrangea macrophylla extract, hydrolyzed okra extract, palmitoyl pentapeptide-4, and sodium citrate within a specific ratio range. The honey extract contains natural polysaccharides, amino acids, and phenolic compounds, possessing the potential to absorb moisture, repair the stratum corneum, and soothe the skin. The Bordeaux leaf extract is rich in polyphenols and flavonoids, which can help improve uneven skin tone and brighten the skin by reducing oxidative stress. The Hydrangea macrophylla extract contains highly active β-glucan, possessing excellent deep moisturizing and transdermal repair capabilities, and can penetrate the skin's base layer to enhance its own water-retention capacity. This product improves dry, dehydrated skin, soothes skin stress damage, and enhances skin tolerance. Hydrolyzed okra extract contains active ingredients such as plant mucilage and phytosterols, which help the skin retain moisture, maintain moisture balance, improve dryness, and leave skin hydrated and radiant. Palmitoyl pentapeptide-4 activates skin fibroblast activity and promotes collagen synthesis, enhancing skin firmness and radiance, and improving skin tone. Sodium citrate, as a formulation compatibility aid, optimizes the compatibility of various active ingredients, improves overall formula stability and activity retention, ensures stable release of each ingredient's efficacy, and helps improve the skin's hydrated and translucent texture. The synergistic effect of these ingredients delivers excellent skin-renewing and moisturizing results. Detailed Implementation
[0013] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features, and effects of the present invention, in conjunction with embodiments, is provided below.
[0014] The honey extract is from Shaanxi Mufan Biotechnology Co., Ltd., product number MF-00099; Bordeaux leaf extract is from Shaanxi Mufan Biotechnology Co., Ltd., product number MF-01383; The extract of Hydrangea macrophylla is from Shaanxi Mufan Biotechnology Co., Ltd., product number MF-01447; The hydrolyzed coffee okra extract is from Shaanxi Xiazhou Biotechnology Co., Ltd., model number AS-01; Palmitoyl pentapeptide-4 is from Jining Tangyi Chemical Co., Ltd., and its product name is Pentapeptide. Sodium citrate comes from Jining Tangyi Chemical Co., Ltd., and its product name is sodium citrate.
[0015] Unless otherwise specified, all other materials, reagents, etc. used in all embodiments and comparative examples of this invention are commercially available.
[0016] Example 1
[0017] A skin-renewing and moisturizing composition, comprising, by weight, 0.6 parts honey extract, 0.15 parts Bordeaux leaf extract, 0.1 parts Hydrangea macrophylla extract, 0.6 parts hydrolyzed Okra extract, 0.2 parts palmitoyl pentapeptide-4, and 0.2 parts sodium citrate.
[0018] Example 2
[0019] A skin-renewing and moisturizing composition, comprising, by weight, 0.5 parts honey extract, 0.1 parts Bordeaux leaf extract, 0.08 parts Hydrangea macrophylla extract, 0.4 parts hydrolyzed Okra extract, 0.15 parts palmitoyl pentapeptide-4, and 0.15 parts sodium citrate.
[0020] Example 3
[0021] A skin-renewing and moisturizing composition, comprising, by weight, 0.7 parts honey extract, 0.2 parts Bordeaux leaf extract, 0.12 parts Hydrangea macrophylla extract, 0.8 parts hydrolyzed Okra extract, 0.25 parts palmitoyl pentapeptide-4, and 0.25 parts sodium citrate.
[0022] Example 4
[0023] A skin-renewing and moisturizing composition, comprising, by weight, 0.4 parts honey extract, 0.01 parts Bordeaux leaf extract, 0.05 parts Hydrangea macrophylla extract, 0.1 parts hydrolyzed Okra extract, 0.05 parts palmitoyl pentapeptide-4, and 0.1 parts sodium citrate.
[0024] Example 5
[0025] A skin-renewing and moisturizing composition, comprising, by weight, 1 part honey extract, 0.3 parts Bordeaux leaf extract, 0.15 parts Hydrangea macrophylla extract, 1 part hydrolyzed Okra extract, 0.3 parts palmitoyl pentapeptide-4, and 0.3 parts sodium citrate.
[0026] Comparative Example 1 Compared with Example 1, the difference is that the honey extract in Comparative Example 1 was removed from the composition, and the missing amount was made up with an equal weight of Bordeaux leaf extract. Other components and parameters remained the same as in Example 1.
[0027] Comparative Example 2 Compared with Example 1, the difference is that Bordeaux leaf extract was removed from the composition of Comparative Example 2, and the missing amount was made up with an equal weight of Hydrangea macrophylla extract. Other components and parameters remained the same as in Example 1.
[0028] Comparative Example 3 Compared with Example 1, the difference is that the *Hydrangea macrophylla* extract was removed from the composition of Comparative Example 3, and the missing amount was made up with an equal weight of hydrolyzed *Abelmoschus manihot* extract. Other components and parameters remained the same as in Example 1.
[0029] Comparative Example 4 Compared with Example 1, the difference is that the hydrolyzed coffee okra extract was removed from the composition of Comparative Example 4, and the missing amount was made up with an equal weight of palmitoyl pentapeptide-4. Other components and parameters were kept the same as those in Example 1.
[0030] Comparative Example 5 Compared with Example 1, the difference is that palmitoyl pentapeptide-4 was removed from the composition of Comparative Example 5, and the missing amount was made up with an equal weight of sodium citrate. Other components and parameters are the same as those in Example 1.
[0031] Comparative Example 6 Compared with Example 1, the difference is that sodium citrate was removed from the composition of Comparative Example 6, and the missing amount was made up with an equal weight of honey extract. Other components and parameters remained the same as in Example 1.
[0032] Comparative Example 7 Compared with Example 1, the difference is that the raw materials of the composition of Comparative Example 7, by weight, include 1.5 parts honey extract, 0.5 parts Bordeaux leaf extract, 0.01 parts Hydrangea macrophylla extract, 0.01 parts hydrolyzed Okra extract, 0.01 parts palmitoyl pentapeptide-4, and 0.5 parts sodium citrate.
[0033] Comparative Example 8 Compared with Example 1, the difference is that the raw materials of the composition of Comparative Example 8, by weight, include 0.1 parts honey extract, 0.001 parts Bordeaux leaf extract, 0.2 parts Hydrangea macrophylla extract, 1.5 parts hydrolyzed Okra extract, 0.5 parts palmitoyl pentapeptide-4, and 0.01 parts sodium citrate.
[0034] The composition of each embodiment and comparative example is prepared by weighing the corresponding weight parts of the composition and mixing them evenly to obtain the composition.
[0035] Test Example 1: Tyrosinase Inhibition Rate Test Sample solution: Using PBS solution (pH=6.8) as solvent, the skin-renewing and moisturizing compositions prepared in Examples 1-5 or Comparative Examples 1-8 were formulated into a sample solution with a concentration of 2 mg / mL. Grouping: Sample tubes, sample control tubes, negative control tubes, and blank control tubes, with three parallel tubes in each group. Add 1.0 mL of sample solution to each sample tube and sample control tube, and add 1.0 mL of PBS solution to each negative control tube and blank control tube. Add 0.5 mL of 100 U / mL tyrosinase solution to each sample tube and negative control tube, and add 0.5 mL of PBS solution to each sample control tube and blank control tube. Experimental method: Shake each tube to mix thoroughly, incubate in a 30℃ water bath for 10 min, and add 2.0 mL of 5×10⁻⁶ solution to each tube. -4 Incubate with g / mL L-DOPA for 5 min, then measure the absorbance at 475 nm. Record the absorbance of the sample tube as T, the sample control tube as T0, the negative control tube as C, and the blank control tube as C0. Calculate the tyrosinase inhibition rate using the following formula: Tyrosinase inhibition rate (%) = [1 - (T - T0) / (C - CO)] × 100%; The results, after being averaged, are recorded in Table 1 below.
[0036] Table 1
[0037] As shown in Table 1, compared with Comparative Examples 1-8, the compositions prepared in Examples 1-5 can effectively inhibit tyrosinase activity, thereby reducing pigmentation, improving uneven skin tone, and brightening the overall skin tone.
[0038] Application Example 1-5, Comparative Application Example 1-8 The skin-renewing and moisturizing compositions of Examples 1-5 and Comparative Application Examples 1-8 were added to the moisturizing cream at a concentration of 0.5 wt% to obtain the moisturizing creams of Application Examples 1-5 and Comparative Application Examples 1-8, respectively. The formulations of the moisturizing creams are shown in Table 2.
[0039] Table 2
[0040] The preparation methods of the moisturizing creams described in Application Examples 1-5 and Comparative Application Examples 1-8 specifically include the following steps: (1) Accurately weigh the A phase raw material into the emulsifying pot, heat it to 85℃, homogenize it for 3 min, and keep it warm and stir for 30 min; (2) Accurately weigh the B phase raw material into the oil phase pot, heat it to 85°C, and stir it evenly; (3) Transfer the raw materials from the oil phase pot into the emulsifying pot, turn on the homogenizer for 3 minutes, and keep warm and stir for 20 minutes; (4) Turn on the cooling water to cool down to 70°C, add the C phase raw material, homogenize for 3 min, and keep warm and stir for 5 min; (5) Cool down to 45℃, add D phase raw material, and stir for 20 min; (6) Cool down to 38℃, take a sample, filter and discharge the material after it passes the test, let it stand, fill and package it after it passes the test, spray code it, and put the finished product into the warehouse.
[0041] The present invention also provides a blank application example of a moisturizing cream, which differs from the moisturizing cream described in application example 1 only in that the skin-renewing moisturizing composition is not added, and the missing amount is made up with an equal amount of water. The remaining steps and parameters are the same as those in application example 1, and the blank application example of a moisturizing cream is prepared.
[0042] Test Example 2: Human Patch Test Fifty participants (healthy men or women aged 25-55) were selected for testing according to the inclusion criteria, and the selected area was no more than 50 mm². 2 A qualified spot test apparatus with a depth of approximately 1 mm was used. The sample was placed inside the small chamber of the apparatus, and 0.025 mL of the test sample (moisturizing cream prepared in Application Examples 1-5, Control Application Examples 1-8, and the blank application example, along with distilled water) was added. Fifteen test areas of the same size were selected on the volunteers' arms (1-2 cm apart), and each area was covered with hypoallergenic adhesive tape. The tape was gently pressed to ensure even application to the skin. The spot test apparatus was removed after 24 hours. Skin reactions were observed according to the standards in Table 3 at 30 min (after the indentation disappeared), 24 h, and 48 h after removal of the test apparatus, and the results were recorded. If the average irritation score of the application examples was not higher than that of the blank control group, and no case of grade 2 or higher adverse reaction occurred, the product was deemed safe and non-irritating.
[0043] Table 3 Skin Reaction Grading Standards
[0044] After testing, the moisturizing creams containing the skin-renewing and moisturizing composition provided in Application Examples 1-5, Comparative Application Examples 1-8, and Blank Application Examples of the present invention all showed negative reactions after human patch testing, and no adverse reactions occurred during use, indicating that they are safe and non-irritating.
[0045] Test Example 3: Human Efficacy Test According to the Cosmetic Safety Technical Specifications (2015), 70 subjects aged 18-45 with dry and sensitive skin (lactate stinging score >3, skin moisture content 20 C.U-50 C.U) were selected and randomly divided into 14 groups, with 5 people in each group.
[0046] Test method: Subjects were instructed to apply the test product to their face once in the morning and once in the evening, at a dosage of (2.00±0.05) mg / cm³. 2 Massage to absorb the product. The treatment lasted for 28 days. All tests were conducted after a period of uniform cleaning and sitting quietly for 30 minutes in an experimental environment (temperature 20±1℃, humidity 50±10%).
[0047] Testing instruments: A Colorimeter CL400 skin color analyzer was used to measure the corresponding a*, b*, and L* values, and then the ITA° was calculated. A Corneometer® CM825 skin moisture content analyzer was used to measure the relative moisture content of the skin surface.
[0048] During follow-up visits on day 1 (initial values) and day 28, ITA° and TEWL values were measured using testing equipment. The product's skin brightening effect was evaluated based on the ITA° improvement rate; a higher improvement rate indicates a better brightening effect. The product's moisturizing effect was evaluated based on the skin hydration improvement rate; a higher improvement rate indicates a better moisturizing effect. The specific calculation formula is as follows: ITA°=[Arc tan(L*-50) / b*]×180 / π; ITA° value improvement rate (%) = (value before use - value after use) / value before use × 100%; Skin hydration improvement rate (%) = (value after use - value before use) / value before use × 100%; The results, after taking the average, are recorded in Table 4 below.
[0049] Table 4
[0050] As shown in Table 4, the moisturizing cream containing the skin-renewing and moisturizing composition prepared in this invention can effectively brighten skin tone, increase skin moisture content, and has good skin-renewing and moisturizing effects.
[0051] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any indirect modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.
Claims
1. A skin-renewing and moisturizing composition, characterized in that, The raw materials of the skin-renewing and moisturizing composition, by weight, include 0.4-1 parts honey extract, 0.01-0.3 parts Bordeaux leaf extract, 0.05-0.15 parts Hydrangea macrophylla extract, 0.1-1 parts hydrolyzed Okra extract, 0.05-0.3 parts palmitoyl pentapeptide-4, and 0.1-0.3 parts sodium citrate.
2. The skin-renewing and moisturizing composition according to claim 1, characterized in that, The raw materials of the skin-renewing and moisturizing composition, by weight, include 0.5-0.7 parts honey extract, 0.1-0.2 parts Bordeaux leaf extract, 0.08-0.12 parts Hydrangea macrophylla extract, 0.4-0.8 parts hydrolyzed Okra extract, 0.15-0.25 parts palmitoyl pentapeptide-4, and 0.15-0.25 parts sodium citrate.
3. The method for preparing the skin-renewing and moisturizing composition according to claim 1 or 2, characterized in that, The preparation method of the skin-renewing and moisturizing composition includes the following steps: Mix the ingredients evenly according to the formula to obtain the skin-renewing and moisturizing composition.
4. The use of the skin-renewing and moisturizing composition according to claim 1 or 2 in the preparation of cosmetics, characterized in that, The cosmetics include toners, lotions, creams, masks, or freeze-dried powders.
5. The application according to claim 4, characterized in that, The amount of the skin-renewing and moisturizing composition added to the cosmetic is 0.1wt%-1wt%.
6. A moisturizing cream, characterized in that, Includes the skin-renewing and moisturizing composition as described in claim 1 or 2.
7. The moisturizing cream according to claim 6, characterized in that, It also contains excipients acceptable in the cosmetics industry.
8. The moisturizing cream according to claim 7, characterized in that, The excipients acceptable in the cosmetics field include solvents, humectants, thickeners, emulsifiers, skin moisturizers, antioxidants, chelating agents, pH adjusters, preservatives, fragrances, and colorants.