A medicine liquid formula for effectively cleaning wet toxin in body and improving skin itch
Patent Information
- Application Number
- CN202410542203.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-30
- Publication Date
- 2026-10-23
AI Technical Summary
[0003]针对现有技术的不足，本发明的目的在于提供一种有效清理体内湿毒改善皮肤瘙痒的药液配方，该药液配方旨在解决现有技术下刺激性较大，长期使用会导致皮肤的皮脂腺分泌功能减弱，导致湿疹加重，副作用较大的技术问题
[0015]本发明的有益效果：通过多种中草药提取液的合理配伍，对湿疹、脱发、白发和老年皮肤等问题均有较好的治疗效果，直接涂抹于皮肤，无需经过体内循环，可以更快地发挥药效，无刺激性，制成药液，相比固体药剂其分散度大，所以药液中有效成分更容易被皮肤吸收，大大提高了药物的生物利用度，见效快，且原料易于获取，制备的方式简便，纯中草药制成，无副作用，安全健康；
Smart Images
Figure BDA0004821279600000071 
Figure BDA0004821279600000081
Abstract
Description
Technical Field
[0001] This invention relates to the field of pharmaceutical formulation technology, and in particular to a pharmaceutical formulation that effectively clears dampness and toxins from the body and improves itchy skin. Background Technology
[0002] Itching is a symptom of skin disease characterized by itching without primary skin lesions. The etiology of eczema is currently unclear, but it is related to internal factors, external factors, and psychosocial factors. In the acute phase, it manifests as erythema, edema, millet-sized papules, papulovesicles, vesicles, erosion, and exudation. In the subacute phase, redness, swelling, and exudation decrease, and erosions crust over and desquamate. In the chronic phase, it mainly manifests as roughness, thickening, and lichenification. Eczema is prone to recurrence, seriously affecting the patient's quality of life. Current treatments for eczema and itching include basic treatment, local treatment, systemic treatment, physical therapy, and traditional Chinese medicine. However, existing topical medications are generally highly irritating, causing burning sensations and stinging when applied to the affected area. Furthermore, long-term use of corticosteroids may lead to skin atrophy, secondary infections, and dry skin. Long-term use can also weaken the sebaceous gland secretion function, causing dry skin and potentially worsening eczema, resulting in significant side effects. Summary of the Invention
[0003] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a medicinal liquid formula that effectively clears dampness and toxins from the body and improves skin itching. This medicinal liquid formula aims to solve the technical problems of existing technologies, such as high irritation, long-term use leading to weakened sebaceous gland secretion function, resulting in worsening of eczema and significant side effects.
[0004] The technical solution of the present invention is: a medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching, comprising the following components in parts by weight: 50-60 parts of Artemisia argyi extract, 30-40 parts of Platycladus orientalis leaf extract, 30-40 parts of Angelica sinensis extract, 30-40 parts of Paeonia suffruticosa root bark extract and 30-40 parts of Polygonum multiflorum extract.
[0005] Its preparation method is as follows:
[0006] Step 1: Prepare the prescribed amounts of Artemisia argyi extract, Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract and Polygonum multiflorum extract. Pour the Artemisia argyi extract into a mixer. While stirring, add the Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract and Polygonum multiflorum extract in sequence along the inner wall of the mixer. Then continue stirring for 5 to 10 minutes to obtain the medicinal liquid.
[0007] Step 2: Fill the liquid medicine into containers of the specified size and seal them, then store them in a cool, dark place.
[0008] As a preferred method, the preparation steps of mugwort extract are as follows: cut dried mugwort into small pieces and grind it into powder in a grinder. Put the mugwort powder into a container, add alcohol and water in proportion, stir the three together, let it stand in a cool place for 2 to 3 days, then filter it, let it stand for 1 hour, and take the supernatant as mugwort extract.
[0009] Preferably, the weight ratio of artemisia powder, alcohol and water is 1:1 to 1.5:2.5 to 3.
[0010] As a preferred method, the preparation steps of the Platycladus orientalis leaf extract are as follows: take Platycladus orientalis leaves, wash, dry, crush, and pass through a 100-120 mesh sieve. Divide the sieved Platycladus orientalis leaf powder into three equal parts, add acetone at a weight ratio of 2:1 to each part, and perform sealed soaking extraction. The soaking times are 72h, 48h, and 24h, respectively. After filtering the three extracts, combine them to obtain the Platycladus orientalis leaf extract.
[0011] As a preferred method, the preparation steps of Angelica sinensis extract are as follows: after washing and chopping Angelica sinensis, add ethanol and extract at 80°C for 2 hours. Then filter the Angelica sinensis and retain the filtrate as Angelica sinensis extract.
[0012] As a preferred option, the mass ratio of ethanol to angelica is 8:1, and 75% ethanol is selected.
[0013] As a preferred method, the preparation steps of the peony bark extract are as follows: After washing and chopping the peony bark, add 10 to 15 times the amount of water, extract at 80°C for 1.5 to 2 hours, then filter the peony bark, and the retained filtrate is the peony bark extract.
[0014] As a preferred method, the preparation steps of Polygonum multiflorum extract are as follows: after washing Polygonum multiflorum, grind it into powder, add 10 times the amount of water, ethanol or ethyl acetate, extract at 80°C for 2 hours, then filter the Polygonum multiflorum powder, let it stand for 1 hour, and take the supernatant as Polygonum multiflorum extract.
[0015] The beneficial effects of this invention are as follows: Through the rational combination of various Chinese herbal extracts, it has a good therapeutic effect on problems such as eczema, hair loss, gray hair and senile skin. It can be applied directly to the skin without going through the body's circulation, so it can exert its effects more quickly. It is non-irritating. The liquid medicine has a large dispersion compared to solid medicines, so the active ingredients in the liquid medicine are more easily absorbed by the skin, which greatly improves the bioavailability of the drug. It is fast-acting, and the raw materials are easy to obtain. The preparation method is simple. It is made of pure Chinese herbal medicines, has no side effects, and is safe and healthy.
[0016] Mugwort helps fight bacteria and fungi. The special volatile oils in mugwort can effectively prevent skin eczema and have a certain therapeutic effect on itchy skin. Mugwort helps to promote blood circulation and relieve pain. It can also help with local skin redness, swelling and pain caused by itchy skin. Mugwort is pungent and warm in nature. It enters the liver and kidney meridians. It belongs to antibacterial and anti-inflammatory Chinese medicine. It has the effects of warming the meridians and stopping bleeding, dispelling cold and relieving pain. It can relieve and improve scalp oiliness and is beneficial to improve hair loss symptoms.
[0017] Arborvitae leaves can promote hair growth and darken hair, and can treat hair loss and premature graying of hair caused by blood heat. At the same time, arborvitae leaves can clear heat and detoxify, remove dampness and relieve pain, stop bleeding, lower blood pressure and lipids, and improve immunity. The volatile oil in arborvitae leaves has a strong bactericidal effect and can be used to treat skin inflammation, oral inflammation and other diseases.
[0018] Angelica sinensis contains volatile oils, aromatic acids and other components, which have strong anti-inflammatory effects. It can prevent infection and treat inflammation. Angelica sinensis can promote blood circulation, dilate blood vessels and regulate blood flow, thereby relieving symptoms such as pain and swelling.
[0019] Moutan bark has the effect of reducing capillary viscosity and inhibiting platelet aggregation in the body. Moutan bark can cool the blood and stop bleeding, as well as promote blood circulation and remove blood stasis. The paeonol in moutan bark can inhibit serum activity, enhance the body's anti-inflammatory function, and can also effectively eliminate Escherichia coli or Staphylococcus aureus, preventing some bacterial diseases.
[0020] Polygonum multiflorum can darken hair because it contains anti-aging substances and can nourish blood and essence. In addition, it can increase hematopoietic cells in bone marrow and improve hematopoietic function. Polygonum multiflorum can also nourish the liver, reduce fatty liver content, and regulate endocrine function. Detailed Implementation
[0021] The present invention will be further described below with reference to embodiments.
[0022] Example 1
[0023] This invention provides an embodiment: a medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching, comprising the following components in parts by weight: 50 parts of Artemisia argyi extract, 30 parts of Platycladus orientalis leaf extract, 30 parts of Angelica sinensis extract, 30 parts of Paeonia suffruticosa root bark extract and 30 parts of Polygonum multiflorum extract;
[0024] Its preparation method is as follows:
[0025] Step 1: Prepare the prescribed amounts of Artemisia argyi extract, Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa root bark extract, and Polygonum multiflorum extract. Pour the Artemisia argyi extract into a stirrer, and while stirring, add the Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa root bark extract, and Polygonum multiflorum extract in sequence along the inner wall of the stirrer. Continue stirring for 5 minutes to obtain the medicinal liquid. The preparation steps of Artemisia argyi extract are as follows: Cut the dried Artemisia argyi into small pieces and grind it into powder in a grinder. Put the Artemisia argyi powder into a container, add alcohol and water in proportion, and stir the three together thoroughly. Let it stand in a cool place for 2 days, then filter it, let it stand for 1 hour, and take the supernatant as Artemisia argyi extract. The weight ratio of Artemisia argyi powder, alcohol, and water is 1:1:3. The preparation steps of Platycladus orientalis leaf extract are as follows: Take Platycladus orientalis leaves, wash, dry, crush, and pass through a 100-mesh sieve. Divide the sieved Platycladus orientalis leaf powder into three equal parts, and add the weight of each part to the mixture. The following steps were taken for the preparation of angelica extract: Acetone was used in a 2:1 ratio for sealed soaking extraction, with soaking times of 72h, 48h, and 24h respectively. The three extracts were filtered separately and then combined to obtain the arborvitae leaf extract. The preparation steps for angelica extract were as follows: Angelica was washed and chopped, ethanol was added, and it was extracted at 80℃ for 2 hours. Then, the Angelica was filtered, and the retained filtrate was the angelica extract. The mass ratio of ethanol to Angelica was 8:1, and 75% ethanol was used. The preparation steps for peony bark extract were as follows: Peony bark was washed and chopped, 10 times the amount of water was added, and it was extracted at 80℃ for 1.5 hours. Then, the peony bark was filtered, and the retained filtrate was the peony bark extract. The preparation steps for Polygonum multiflorum extract were as follows: Polygonum multiflorum was washed and ground into powder, 10 times the amount of water, ethanol, or ethyl acetate was added, and it was extracted at 80℃ for 2 hours. Then, the Polygonum multiflorum powder was filtered, and after standing for 1 hour, the supernatant was taken as the Polygonum multiflorum extract.
[0026] Step 2: Fill the liquid medicine into containers of the specified size and seal them, then store them in a cool, dark place.
[0027] Example 2
[0028] This invention provides an embodiment: a medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching, comprising the following components in parts by weight: 60 parts of Artemisia argyi extract, 40 parts of Platycladus orientalis leaf extract, 40 parts of Angelica sinensis extract, 40 parts of Paeonia suffruticosa root bark extract and 40 parts of Polygonum multiflorum extract;
[0029] Its preparation method is as follows:
[0030] Step 1: Prepare the prescribed amounts of Artemisia argyi extract, Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa root bark extract, and Polygonum multiflorum extract. Pour the Artemisia argyi extract into a stirrer, and while stirring, add the Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa root bark extract, and Polygonum multiflorum extract in sequence along the inner wall of the stirrer. Continue stirring for 10 minutes to obtain the medicinal liquid. The preparation steps for Artemisia argyi extract are as follows: Cut dried Artemisia argyi into small pieces and grind it into powder in a grinder. Put the Artemisia argyi powder into a container, add alcohol and water in proportion, and stir thoroughly. Let it stand in a cool place for 3 days, then filter it, let it stand for 1 hour, and take the supernatant as Artemisia argyi extract. The weight ratio of Artemisia argyi powder, alcohol, and water is 1:1.5:2.5. The preparation steps for Platycladus orientalis leaf extract are as follows: Take Platycladus orientalis leaves, wash, dry, crush, and pass through a 120-mesh sieve. Divide the sieved Platycladus orientalis leaf powder into three equal portions, and add... The following steps were taken for the preparation of angelica extract: Acetone was added at a weight ratio of 2:1, and the extracts were sealed and soaked for 72 hours, 48 hours, and 24 hours respectively. The three extracts were filtered separately and then combined to obtain the arborvitae leaf extract. The preparation steps for angelica extract were as follows: Angelica was washed and chopped, ethanol was added, and the extract was extracted at 80℃ for 2 hours. Then, the Angelica was filtered, and the filtrate was obtained as the angelica extract. The mass ratio of ethanol to Angelica was 8:1, and 75% ethanol was used. The preparation steps for peony bark extract were as follows: Peony bark was washed and chopped, 15 times the amount of water was added, and the extract was extracted at 80℃ for 2 hours. Then, the peony bark was filtered, and the filtrate was obtained as the peony bark extract. The preparation steps for Polygonum multiflorum extract were as follows: Polygonum multiflorum was washed and ground into powder, 10 times the amount of water, ethanol, or ethyl acetate was added, and the extract was extracted at 80℃ for 2 hours. Then, the Polygonum multiflorum powder was filtered, and after standing for 1 hour, the supernatant was obtained as the Polygonum multiflorum extract.
[0031] Step 2: Fill the liquid medicine into containers of the specified size and seal them, then store them in a cool, dark place.
[0032] Example 3
[0033] This invention provides an embodiment: a medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching, comprising the following components in parts by weight: 55 parts of Artemisia argyi extract, 35 parts of Platycladus orientalis leaf extract, 35 parts of Angelica sinensis extract, 35 parts of Paeonia suffruticosa root bark extract and 35 parts of Polygonum multiflorum extract;
[0034] Its preparation method is as follows:
[0035] Step 1: Prepare the prescribed amounts of Artemisia argyi extract, Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract, and Polygonum multiflorum extract. Pour the Artemisia argyi extract into a stirrer, and while stirring, add the Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract, and Polygonum multiflorum extract sequentially along the inner wall of the stirrer. Continue stirring for 8 minutes to obtain the medicinal liquid. The preparation steps for Artemisia argyi extract are as follows: Cut dried Artemisia argyi into small pieces and grind it into powder in a grinder. Put the Artemisia argyi powder into a container, add alcohol and water in proportion, and stir thoroughly. Let it stand in a cool place for 3 days, then filter it, let it stand for 1 hour, and take the supernatant as Artemisia argyi extract. The weight ratio of Artemisia argyi powder, alcohol, and water is 1:1:2.5. The preparation steps for Platycladus orientalis leaf extract are as follows: Take Platycladus orientalis leaves, wash, dry, crush, and pass through a 100-mesh sieve. Divide the sieved Platycladus orientalis leaf powder into three equal portions, and add alcohol and water to each portion separately. The following steps were taken for the preparation of angelica extract: Acetone was used in a 2:1 ratio for sealed soaking extraction, with soaking times of 72h, 48h, and 24h respectively. The three extracts were filtered separately and then combined to obtain the Platycladus orientalis leaf extract. The preparation steps for angelica extract were as follows: Angelica was washed and chopped, ethanol was added, and it was extracted at 80℃ for 2 hours. Then, the Angelica was filtered, and the retained filtrate was the Angelica extract. The mass ratio of ethanol to Angelica was 8:1, and 75% ethanol was used. The preparation steps for peony bark extract were as follows: Peony bark was washed and chopped, 12 times the amount of water was added, and it was extracted at 80℃ for 1.5 hours. Then, the Peony bark was filtered, and the retained filtrate was the Peony bark extract. The preparation steps for Polygonum multiflorum extract were as follows: Polygonum multiflorum was washed and ground into powder, 10 times the amount of water, ethanol, or ethyl acetate was added, and it was extracted at 80℃ for 2 hours. Then, the Polygonum multiflorum powder was filtered, and after standing for 1 hour, the supernatant was taken as the Polygonum multiflorum extract.
[0036] Step 2: Fill the liquid medicine into containers of the specified size and seal them, then store them in a cool, dark place.
[0037] Experimental Example
[0038] A: Male, 10 years old, presented with erythema, edema, itching, etc., and was diagnosed with eczema by a doctor;
[0039] Take the medicinal liquid from Examples 1, 2, and 3 and apply it to the affected area three times a day.
[0040] B: Female, 30 years old, hair on the top of her head is thinning, and her hairline is not receding significantly.
[0041] Take the medicinal liquid from Examples 1, 2 and 3, apply it to the scalp and massage the scalp with your fingertips for 5 minutes, twice a day.
[0042] C: Male, 35 years old, gray hair starts to turn from the temples on both sides, gradually increases and slowly spreads to the top of the head;
[0043] Take the medicinal liquid from Examples 1, 2 and 3, apply it to the scalp and massage the scalp with your fingertips for 5 minutes, twice a day.
[0044] D: Male, 75 years old, with obvious itchy skin on his back, which occurs more frequently at night;
[0045] Take the medicinal liquid from Examples 1, 2 and 3, apply it to the back twice a day.
[0046] Table 1 shows the physical performance indicators of A, B, C, and D after using the medicinal solution of this invention.
[0047]
[0048]
[0049] Table 1
[0050] The embodiments of the present invention have been described in detail above. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.
Claims
1. A medicinal liquid formula for effectively clearing dampness and toxins from the body and improving itchy skin, characterized in that, It includes the following components in parts by weight: 50-60 parts of Artemisia argyi extract, 30-40 parts of Platycladus orientalis leaf extract, 30-40 parts of Angelica sinensis extract, 30-40 parts of Paeonia suffruticosa root bark extract, and 30-40 parts of Polygonum multiflorum extract. Its preparation method is as follows: Step 1: Prepare the prescribed amounts of Artemisia argyi extract, Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract and Polygonum multiflorum extract. Pour the Artemisia argyi extract into a mixer. While stirring, add the Platycladus orientalis leaf extract, Angelica sinensis extract, Paeonia suffruticosa extract and Polygonum multiflorum extract in sequence along the inner wall of the mixer. Then continue stirring for 5 to 10 minutes to obtain the medicinal liquid. Step 2: Fill the liquid medicine into containers of the specified size and seal them, then store them in a cool, dark place.
2. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 1, characterized in that: The preparation steps of mugwort extract are as follows: Cut dried mugwort into small pieces and grind it into powder in a grinder. Put the mugwort powder into a container, add alcohol and water in proportion, stir the three together, let it stand in a cool place for 2 to 3 days, then filter it, let it stand for 1 hour, and take the supernatant as mugwort extract.
3. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 2, characterized in that: The weight ratio of mugwort powder, alcohol and water is 1:1 to 1.5:2.5 to 3.
4. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 1, characterized in that: The preparation steps of the arborvitae leaf extract are as follows: Take arborvitae leaves, wash, dry, crush, and pass through a 100-120 mesh sieve. Divide the sieved arborvitae leaf powder into three portions, add acetone at a weight ratio of 2:1 to each portion, and seal and soak for extraction. The soaking times are 72h, 48h, and 24h, respectively. After filtering the three extracts, combine them to obtain the arborvitae leaf extract.
5. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 1, characterized in that: The preparation steps of Angelica sinensis extract are as follows: After washing and chopping Angelica sinensis, add ethanol and extract at 80℃ for 2 hours. Then filter the Angelica sinensis and retain the filtrate as Angelica sinensis extract.
6. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 5, characterized in that: The mass ratio of ethanol to angelica is 8:1, and 75% ethanol is used.
7. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 1, characterized in that: The preparation steps of peony bark extract are as follows: After washing and chopping peony bark, add 10 to 15 times the amount of water, extract at 80℃ for 1.5 to 2 hours, then filter the peony bark, and the retained filtrate is the peony bark extract.
8. The medicinal liquid formula for effectively clearing dampness and toxins from the body and improving skin itching according to claim 1, characterized in that: The preparation steps of Polygonum multiflorum extract are as follows: after washing Polygonum multiflorum, grind it into powder, add 10 times the amount of water, ethanol or ethyl acetate, extract at 80℃ for 2 hours, then filter the Polygonum multiflorum powder, let it stand for 1 hour, and take the supernatant as Polygonum multiflorum extract.