A burn cream and a preparation method thereof

Abstract

The present application belongs to the technical field of traditional Chinese medicine ointment for treating scald, and specifically discloses a scald ointment and a preparation method. The scald ointment is prepared from raw materials including Centella asiatica, licorice, Sanguisorba officinalis, Arnebia euchroma, giant knotweed, rhubarb, Coptis chinensis and Bletilla striata, and is based on horse oil as a matrix and beeswax as an excipient, so as to play the roles of clearing heat and resisting inflammation, inhibiting bacteria and resisting infection, promoting the growth of granulation and epithelial tissue on a wound surface, and resisting scar formation. The preparation process includes targeted cleaning and drying of medicinal materials, crushing and sieving, constant-temperature soaking in horse oil, temperature-controlled preparation of medicinal oil, multi-stage gauze filtration, addition of beeswax excipient, and cooling and solidification, and the temperature, time and material ratio of each process are strictly controlled to ensure the efficacy. The present application is externally used by exposure, and is applied twice a day, so as to relieve pain, promote the drying and scabbing of blisters, accelerate wound healing, and reduce the risk of infection and scar hyperplasia.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine ointments for treating burns, specifically to a burn ointment and its preparation method. Background Technology

[0002] Burns are a common traumatic injury in daily life, mostly caused by heat sources such as high-temperature liquids, solids, flames, and steam damaging skin tissue. Clinically, they often manifest as symptoms such as redness, swelling, blisters, ulceration, and burning pain. In severe cases, skin tissue necrosis, wound infection, delayed healing, and even scarring and pigmentation may occur. Burns not only cause severe physical pain to patients but also affect the appearance of the skin and normal limb function, impacting the patient's quality of life.

[0003] Currently, traditional Chinese herbal medicines mainly include scab-preserving medicines, scab-removing medicines, and medicines that promote the growth of epithelium and granulation tissue. Scab-preserving medicines, such as Polygonum cuspidatum and Ilex chinensis, mainly have astringent and antibacterial effects; scab-removing medicines, such as Healing Wound No. 10 Ointment, Burning Ointment, and Scald Ointment, mainly promote the separation of necrotic tissue and the formation of new granulation tissue; medicines that promote the growth of epithelium and granulation tissue, such as Bristle Oil and Eight-Wet Ointment, mainly promote the growth of epithelium and granulation tissue.

[0004] However, the aforementioned traditional medications still have problems such as long treatment courses, slow healing, and easy infection, and may even form hard scabs that do not heal, affecting skin development. Summary of the Invention

[0005] The purpose of this invention is to provide a burn ointment and its preparation method to solve the problems of long treatment courses, slow healing, and easy infection that still exist with traditional medications.

[0006] To achieve the above objectives, the basic solution provided by the present invention is as follows: a burn ointment comprising the following ingredients: 15-21g of Centella asiatica, 9-15g of licorice, 9-15g of Sanguisorba officinalis, 18-24g of Lithospermum erythrorhizon, 6-12g of Polygonum cuspidatum, 21-27g of rhubarb, 3-9g of Coptis chinensis, 9-15g of Bletilla striata, 350-450g of horse oil, and 45-60g of beeswax.

[0007] The beneficial effects of this invention are as follows: The burn ointment of this invention, through the compatibility and synergistic effect of various raw medicinal materials, has good effects of clearing heat and reducing inflammation, inhibiting bacteria and preventing infection, repairing wounds and preventing scarring. The combination of Lithospermum erythrorhizon, Rheum palmatum, Coptis chinensis, Polygonum cuspidatum and Sanguisorba officinalis in the formula can play the role of cooling blood and detoxifying, clearing heat and removing blood stasis, inhibiting bacteria and reducing inflammation. Centella asiatica, Sanguisorba officinalis and Bletilla striata can effectively promote the growth of granulation tissue and epithelial tissue in the wound and accelerate the healing speed of burn wounds. Licorice can harmonize the bitter and cold properties of the various medicines in the formula, alleviate the irritation of the medicinal materials, and avoid secondary irritation to the damaged wound. Using horse oil as the base of the ointment, it can adhere to and nourish the damaged skin, and work with the effective ingredients of each medicinal material to exert the medicinal effect. The burn ointment of this invention has a fast therapeutic effect, easily forms scabs, and has a certain anti-infection ability, which can reduce the risk of wound infection. It can be used in the open method, does not easily melt or flow, and can form an effective protective layer on the wound to isolate pathogenic microorganisms. It has low sensitization, strong repair, and is not prone to scar hyperplasia, which is conducive to wound healing and skin function recovery.

[0008] Option 2, a preferred option to the basic option, includes the following steps: S1. Pre-treatment of medicinal materials: First, all medicinal materials are washed, and then dried using different methods according to the characteristics of different medicinal materials. S2. Herbal powdering: After all the herbs are dried, they are pulverized using a universal pulverizer. The pulverized powder is then sieved through a No. 2-4 pharmacopoeia sieve 1-2 times. S3. Soaking the medicinal powder: Add horse oil to a water bath at a constant temperature of 40℃. The total mass ratio of horse oil to medicinal powder is 4:1. Then add all the sieved medicinal powder to the horse oil and soak for 24~48 hours to obtain medicinal oil. S4. Heating of medicinal oil and powder: After the medicinal powder has been soaked, pour the 40℃ medicinal oil and powder into a stainless steel pot and heat it continuously on the lowest flame of the gas stove. The final oil temperature is controlled at 110~130℃. The time from putting the medicinal materials into the pot to taking them out is 60~90 minutes. When the surface of the medicinal materials is yellowish-brown, the texture is dry, and there is a medicinal aroma without a burnt smell, turn off the heat and let the oil temperature stand and cool down to 80~90℃ before removing the residue. S5. Filtration: When the oil temperature cools to 80~90℃, use a medicine spoon to scoop the medicine oil into the center of 4~8 layers of gauze in batches, place it in a container below, and let it filter by natural gravity. After the medicine oil on the gauze has flowed out and the gauze and medicine residue have cooled to room temperature, first gather the gauze around to form a gauze bag, insert a wooden stick into the gauze bag containing medicine residue, wear heat-resistant gloves and twist the gauze bag in the opposite direction to squeeze out the medicine oil from the medicine residue. The squeezed medicine oil falls into the container below. The recovery rate of the medicine oil squeezed out of the medicine residue is 10% of the medicine oil. S6. Formulation: After the medicated oil has cooled to 50°C, add white beeswax and heat to 70-80°C. The mass ratio of beeswax to medicated oil is 2:15. Stir 2-4 times per minute for 5 minutes until the liquid is uniform in color, free of flocculent matter or sediment, has a medicinal aroma without a burnt smell, and feels smooth and granular when stirred. Then cool the medicated oil to 60-70°C. While the medicated oil is still liquid, quickly pour it into the first strainer for initial filtration. Place a sterilized container underneath to collect the liquid. After the initial filtration, use the second strainer for secondary filtration until all the medicated oil is drained. Then allow it to cool naturally until it solidifies to obtain the finished burn ointment.

[0009] Option 3, which is the preferred option of Option 2, involves cleaning the medicinal materials in S1 as follows: Rhubarb, Sanguisorba officinalis, Polygonum cuspidatum, Coptis chinensis, Glycyrrhiza uralensis, Lithospermum erythrorhizon, and Bletilla striata should be gently brushed with a soft brush under running water to remove the mud from the surface pits. Bletilla striata is rich in mucilage and easily becomes sticky after absorbing water, so it should be removed immediately after washing. Lithospermum erythrorhizon is easily stained, so it should not be rubbed vigorously. Centella asiatica is relatively soft, so when cleaning it, put it in a basin and stir it gently to let the mud and sand settle, then scoop it out with a strainer and rinse it again under running water.

[0010] Option 4, a preferred option of Option 2, involves the following drying methods for the medicinal materials in S1: Polygonum cuspidatum is dried in hot air at 60℃ for 7 hours, with a spread thickness of 3±0.5mm, and turned once during the drying process. The moisture content after drying is below 5%. Bletilla striata is dried in hot air at 60℃ until the moisture content reaches 40%, then sliced, and subsequently dried in hot air at 60℃ until the moisture content is below 12%. Coptis chinensis is dried in hot air at 60℃ for 3-5 hours until the moisture content is below 12%. Rhubarb is baked in two stages with hot air at 60-70℃ until the moisture content is below 15%; Centella asiatica is cooled and then dried with hot air at 50-110℃ for 1-2 hours; Licorice is dried with hot air at 60-70℃ for 4-5 hours until the moisture content is below 12%; Sanguisorba officinalis is dried with hot air at 60℃ until it makes a crisp sound when broken, and the moisture content after drying is below 14%; Lithospermum erythrorhizon is cut into thick slices and sun-dried until the moisture content after sun-drying is below 15%.

[0011] Option 5, an optimal choice of Option 4, involves a two-stage drying process for rhubarb: The first stage involves drying at 50-60℃ for 12-24 hours, until the rhubarb surface is noticeably wrinkled, slightly hardened, not easily deformed by hand, and the cross-section begins to darken. Then, remove the rhubarb and allow it to cool for 12-24 hours. After cooling, proceed with the second stage of drying at 60-70℃ for 24-48 hours, turning it over every 4-6 hours until the cross-section is uniformly colored, firm, and produces a crisp sound when tapped. After drying, remove the rhubarb, allow it to cool to room temperature, and then bag it for storage.

[0012] Option 6, which is the preferred option of Option 2, involves heating the medicinal oil and powder from an initial temperature of 40°C to 110-130°C in 8-15 minutes, with temperature measured once per minute and manual stirring 2-4 times per minute. Attached Figure Description

[0013] Figure 1 This is a photograph of the wound on the first day of treatment for Case 1 in this experiment; Figure 2 This is a photograph of the wound on the second day after the first patient's visit. Figure 3 This is a photograph of the wound on the third day after Case 1's visit. Figure 4 This is a photograph of the wound on the fourth day after Case 1's visit. Figure 5 This is a photograph of the wound on the fifth day after Case 1's visit. Figure 6 This is a photograph of the wound on the sixth day after Case 1's visit. Figure 7 This is a photograph of the wound on the seventh day after the patient's visit in Case 1 of the experiment. Figure 8 This is a photograph of the wound on the eighth day after Case 1's visit. Figure 9 This is a photograph of the wound on the ninth day after Case 1's visit. Figure 10 This is a photograph of the wound on the tenth day after Case 1's visit. Figure 11 Photograph of the affected area on the eleventh day after Case 1's visit; Figure 12 This is a photograph of the wound on the twelfth day after Case 1's visit. Figure 13 Photograph of the wound at the site of Case 1 on the thirteenth day of treatment; Figure 14 This is a photograph of the wound on the first day of treatment for Case 2 in this experiment; Figure 15 This is a photograph of the wound on the third day after Case 2's visit. Figure 16 This is a photograph of the wound on the fourth day after Case 2's visit. Figure 17 This is a photograph of the wound on the ninth day after Case 2's visit. Figure 18 Photograph of the affected area on the eleventh day after Case 2's visit; Figure 19 This is a photograph of the wound on the twelfth day after Case 2's visit. Figure 20 Photograph of the wound on the thirteenth day of the patient's visit in Case 2 of the experiment; Figure 21 This is a photograph of the wound on the fourteenth day after Case 2's visit. Figure 22 This is a photograph of the wound on the 18th day after Case 2's visit. Figure 23 This is a photograph of the wound on the 21st day after Case 2's visit. Figure 24 This is a photograph of the wound on the 40th day after Case 2's visit. Figure 25 This is a photograph of the wound on the first day of treatment for Case 3 in this experiment; Figure 26 This is a photograph of the wound on the fifth day after Case 3's visit. Figure 27 This is a photograph of the wound on the seventh day after the visit of Case 3 in the experiment; Figure 28 Photograph of the wound on the eleventh day after the visit of Case 3 in this experiment; Figure 29 This is a photograph of the wound on the first day of treatment for Case 4 in this experiment; Figure 30 This is a photograph of the wound on the second day after the visit of Case 4 in the experiment; Figure 31 This is a photograph of the wound on the fourth day after Case 4's visit. Figure 32 This is a photograph of the wound on the fifth day after Case 4's visit. Figure 33 This is a photograph of the wound on the sixth day after Case 4's visit. Figure 34 This is a photograph of the wound on the seventh day after the patient's visit in Case 4 of the experiment. Figure 35 This is a photograph of the wound on the eighth day after Case 4's visit. Figure 36 This is a photograph of the wound on the ninth day after Case 4's visit. Figure 37 Photograph of the wound on the eleventh day after the visit of Case 4 in this experiment; Figure 38 This is a photograph of the wound on the seventeenth day after Case 4's visit. Detailed Implementation

[0014] The present invention will be further described in detail below through specific embodiments: A burn ointment comprising the following ingredients: 15-21g of Centella asiatica, 9-15g of licorice, 9-15g of Sanguisorba officinalis, 18-24g of Lithospermum erythrorhizon, 6-12g of Polygonum cuspidatum, 21-27g of rhubarb, 3-9g of Coptis chinensis, 9-15g of Bletilla striata, 350-450g of horse oil, and 45-60g of beeswax.

[0015] The above-mentioned burn ointment is prepared by the following method, with the specific steps as follows: S1. Pre-treatment of medicinal materials: First, all medicinal materials are cleaned. The cleaning method is as follows: Rhubarb, Sanguisorba officinalis, Polygonum cuspidatum, Coptis chinensis, Glycyrrhiza uralensis, Lithospermum erythrorhizon, and Bletilla striata are gently brushed with a soft brush under running water to remove the dirt from the surface pits. Bletilla striata is rich in mucilage and easily becomes sticky after absorbing water, so it should be removed immediately after washing. Lithospermum erythrorhizon is easy to stain, so it should not be rubbed vigorously. Centella asiatica is relatively soft, so when cleaning it, put it in a basin and stir it gently to let the mud and sand settle, then remove it with a slotted spoon and rinse it again under running water. The cleaning standard for all medicinal materials is: the surface is clean and free of mud, sand, impurities, and foreign objects. After washing, different drying methods are used for different medicinal materials according to their characteristics. The drying methods are as follows: Polygonum cuspidatum is dried in hot air at 60℃ for 7 hours, with a spread thickness of 3±0.5mm, and turned once during the process. The moisture content after drying is less than 5%. Bletilla striata is dried in hot air at 60℃ until the moisture content is 40%, then sliced, and then dried in hot air at 60℃ until the moisture content is less than 12%. Coptis chinensis is dried in hot air at 60℃ for 3-5 hours until the moisture content is less than 12%. Rhubarb is baked in two stages in hot air at 60-70℃. The two-stage baking is mainly to prevent the outside from being dry and the inside from being damp, and to prevent the core from becoming pithy and moldy. At the same time, it protects the effective components and improves the quality of the medicinal materials. The specific method of the two-stage baking is as follows: the temperature of the first stage is 50-60℃, and the drying time is 12-24 hours, until the surface of the rhubarb is obviously wrinkled and slightly hard. Rhubarb is dried until it is not easily deformed by hand and the cross-section begins to darken in color. It is then removed and spread out to cool for 12-24 hours. After cooling, it undergoes a second drying stage at 60-70℃ for 24-48 hours, turning it every 4-6 hours. It is dried until the cross-section is uniformly colored, firm, and produces a crisp sound when tapped, with a moisture content below 15%. After drying, the rhubarb is removed, spread out to cool to room temperature, and then bagged for storage. Centella asiatica is cooled and then dried in hot air at 50-110℃ for 1-2 hours. Licorice is dried in hot air at 60-70℃ for 4-5 hours until the moisture content is below 12%. Sanguisorba officinalis is dried in hot air at 60℃ until it makes a crisp sound when broken, with a moisture content below 14%. Lithospermum erythrorhizon is cut into thick slices and sun-dried until the moisture content is below 15%. S2. Herbal powdering: After all the herbs are dried, they are pulverized using a universal pulverizer. The pulverized powder is then sieved through a No. 2-4 pharmacopoeia sieve 1-2 times. S3. Soaking the medicinal powder: Add horse oil to a water bath at a constant temperature of 40℃. The total mass ratio of horse oil to medicinal powder is 4:1. Then add all the sieved medicinal powder to the horse oil and soak for 24~48 hours to obtain medicinal oil. S4. Heating of medicinal oil and powder: After the medicinal powder has been soaked, pour the 40℃ medicinal oil and powder into a stainless steel pot and heat it continuously on the lowest flame of a gas stove. The final oil temperature is controlled at 110~130℃. The time from when the medicinal materials are put into the pot to when they are taken out is 60~90 minutes. The time from when the medicinal oil and powder are heated from the initial temperature of 40℃ to 110~130℃ is 8~15 minutes. During this time, the temperature is measured once every minute, and the mixture is manually stirred 2~4 times per minute. When the surface of the medicinal materials is yellowish-brown, the texture is dry, and there is a medicinal aroma without a burnt smell, turn off the heat and let the oil temperature stand and cool down to 80~90℃ before removing the residue. S5. Filtration: When the oil temperature cools to 80~90℃, use a medicine spoon to scoop the medicinal oil into the center of 4~8 layers of gauze in batches. Place a container below to collect the oil and let it filter by gravity. After the medicinal oil on the gauze has drained and the gauze and medicinal residue have cooled to room temperature, first gather the gauze around to form a gauze bag. Insert a wooden stick into the gauze bag containing the medicinal residue. Wearing heat-resistant gloves, twist the gauze bag in the opposite direction to squeeze out the medicinal oil from the medicinal residue. The squeezed-out medicinal oil falls into the container below. The recovery rate of the oil squeezed out of the medicinal residue is 10% of the medicinal oil. To obtain a clearer medicinal oil, a second filtration can be performed. First, replace the clean gauze with 6~8 layers of gauze and repeat the filtration steps in S5 above. S6. Formulation: After the medicated oil has cooled to 50°C, add white beeswax and heat to 70-80°C. The mass ratio of beeswax to medicated oil is 2:15. Stir 2-4 times per minute for 5 minutes until the liquid is uniform in color, free of flocculent matter or sediment, has a medicinal aroma without a burnt smell, and feels smooth and granular when stirred. Then cool the medicated oil to 60-70°C. While the oil is still liquid, quickly pour it into a strainer for filtration. Place a sterilized container underneath to collect the liquid. While the oil is still liquid, quickly pour it into the first strainer for initial filtration. Place a sterilized container underneath to collect the liquid. After the initial filtration, use a second strainer for secondary filtration until all the oil is drained. The temperature of the first and second strainers should be 70-80°C. The mesh size of the first and second strainers should correspond to a No. 7 or No. 8 pharmacopoeia sieve. Then allow it to cool naturally until it solidifies to obtain the finished burn ointment. Allow it to solidify naturally to avoid premature moisture generation when sealing.

[0016] Effects of each medicinal material in the above scald ointment: Lithospermi Radix can clear heat and cool blood, activate blood circulation to dissipate blood stasis, can resolve skin ecchymosis, and can also detoxify and promote the eruption of rashes; Rhei Radix et Rhizoma can purge to relax bowels, remove accumulated stagnation in the body, and can also clear heat and reduce internal fire, cool blood and detoxify, activate blood circulation to dissipate blood stasis, regulate and unblock the meridians, and clear and drain damp-heat at the same time; Centellae Herba has the effects of clearing heat and draining dampness, detoxifying and reducing swelling; Sanguisorbae Radix is a commonly used key medicinal material for treating burns, which can cool blood and stop bleeding, detoxify and astringe sores, not only can accelerate wound healing, but also has an anti-inflammatory effect; Polygoni Cuspidati Rhizoma can promote gallbladder function to reduce jaundice, clear heat and detoxify, dissipate blood stasis and relieve pain, and can also resolve phlegm and relieve cough at the same time; the effect of Coptidis Rhizoma is to clear heat and dry dampness, purge fire and detoxify; Bletillae Rhizoma can astringe to stop bleeding, reduce swelling and promote tissue regeneration, which can promote the growth of granulation tissue and accelerate wound healing; Glycyrrhizae Radix et Rhizoma can tonify the spleen and boost qi, clear heat and detoxify, expel phlegm and relieve cough, moderate and relieve spasm and pain, and can also harmonize the medicinal properties of all the medicinal materials in the formula, moderate the irritancy of different medicinal materials and reduce incompatibility conflicts; Horse oil is an auxiliary material, which has very good effects on fading pigmentation, improving dry skin, and relieving muscle spasm and pain.

[0017] The entire compatibility formula of the above scald ointment takes medicinal materials with bitter and cold properties as the core, which is mainly used to resolve heat toxin caused by scald, repair the burn of skin and muscle, and improve the state of body fluid consumption, as well as disorder of qi, blood, nutrient and defense after scald. Lithospermi Radix and Rhei Radix et Rhizoma in the formula are medicinal materials with bitter and cold properties, which serve as the monarch drugs of the entire prescription, focusing on exerting the effects of cooling blood and reducing swelling, clearing heat and detoxifying; Centellae Herba, Sanguisorbae Radix and Polygoni Cuspidati Rhizoma serve as the auxiliary minister drugs, which jointly clear heat and dissipate blood stasis, clear and disperse the accumulated heat toxin under the skin and in the muscles, prevent the heat toxin from stagnating and not dispersing in the local area, and at the same time can nourish the body fluid consumed after scald, and relieve the swelling and pain discomfort caused by heat toxin burn; Bletillae Rhizoma and Glycyrrhizae Radix et Rhizoma serve as the adjuvant drugs, Bletillae Rhizoma focuses on reducing swelling and promoting tissue regeneration and repair of the wound; Glycyrrhizae Radix et Rhizoma can not only nourish the spleen and stomach and support healthy qi, but also moderate the irritancy of the bitter and cold medicinal materials in the prescription, so as to avoid the medicinal materials from damaging the body; Coptidis Rhizoma serves as the conductant drug, which is used to guide the medicinal power and enhance the heat-clearing and detoxifying effect of the monarch drugs; finally, horse oil is used as the base of the ointment, which has strong moisturizing property, can nourish the damaged skin and muscle, and help the repair of skin and flesh tissues.

[0018] Example 1

[0019] A scald ointment, which comprises the following raw materials: 18g of Centellae Herba, 11g of Glycyrrhizae Radix et Rhizoma, 12g of Sanguisorbae Radix, 21g of Lithospermi Radix, 9g of Polygoni Cuspidati Rhizoma, 24g of Rhei Radix et Rhizoma, 4g of Coptidis Rhizoma, 11g of Bletillae Rhizoma, 432g of horse oil and 57.6g of beeswax; the scald ointment in this example is prepared by the above preparation method.

[0020] The scald ointment prepared from the raw materials in Example 1 is used to treat the scalded part of the patient, and the treatment cases are as follows: Test Example 1 As shown in Figures 1 to 13As shown: Ms. Wang, female, 54 years old, accidentally scalded the back of her right hand with boiling water at home two days before seeking medical treatment, resulting in three wounds. The wounds immediately became red, swollen and hot after the injury. Two of the larger wounds gradually developed tension blisters of varying sizes, while the remaining wound did not develop blisters. The pain was severe. No treatment was received between the time of the burn and when she sought medical treatment, and the pain did not subside. The wound remained red, swollen, hot and painful, and the blisters did not resolve on their own.

[0021] Treatment regimen: Wound pretreatment: Rinse the wound with saline solution before each medication application, wipe away necrotic epidermis and secretions, and clean the wound.

[0022] Administration method: Take the burn ointment prepared using Example 1 as the raw material and apply it evenly to the entire burn wound, until the ointment completely covers the wound and extends 0.5cm beyond the edge of the wound. The thickness of the ointment should be 1~2mm.

[0023] Dosage frequency: twice daily.

[0024] Treatment results: After 1 day of medication, the pain was reduced and the largest blister began to dry up; on the 3rd day of medication, all the blisters began to dry up and the pain was further relieved; after 6 days of medication, all the blisters completely dried up; after 13 days of medication, the scabs gradually fell off naturally and the wound healed.

[0025] Experimental Example 2 like Figures 14 to 24 The patient, Ms. Zai, 58 years old, accidentally scalded her left armpit with boiling water at home 10 days prior to her visit. Immediately after the injury, the wound became red, swollen, and hot, and tension blisters of varying sizes appeared on the wound. She sought medical attention 10 days after the burn. She had not received any treatment between the day of the burn and the time of her visit. The burn was assessed as a deep second-degree to superficial second-degree burn. The pain had not subsided and showed a tendency to worsen. The wound remained red, swollen, hot, and painful, and the blisters had not been absorbed spontaneously.

[0026] Treatment regimen: Wound pretreatment: Rinse the wound with saline solution before each medication application, wipe away necrotic epidermis and secretions, and clean the wound.

[0027] Administration method: Take the burn ointment prepared using Example 1 as the raw material and apply it evenly to the entire burn wound, until the ointment completely covers the wound and extends 0.5cm beyond the edge of the wound. The thickness of the ointment should be 1-2mm. For blisters and areas with poor healing, the thickness should be increased as appropriate.

[0028] Dosage frequency: twice daily.

[0029] Treatment results: After 8 days of medication, the pain was reduced, the blisters completely dried up, and the wound began to scab over; on the 13th day of medication, the pain was further relieved, and the scabs began to fall off naturally; after 40 days of medication, the scabs gradually fell off naturally, and the wound healed.

[0030] Experimental Example 3 like Figures 25 to 28 As shown: Ms. Kong, 75 years old, accidentally burned the back of her left hand with hot oil 3 days before seeking medical treatment. She applied sesame oil on the day of the burn until she sought medical treatment, but the burn did not relieve the pain. The assessment was superficial second degree, with blisters and pain. The blisters had ruptured when she sought medical treatment.

[0031] Treatment regimen: Wound pretreatment: Rinse the wound with saline solution before each medication application, wipe away necrotic epidermis and secretions, and clean the wound.

[0032] Administration method: Take the burn ointment prepared using Example 1 as the raw material and apply it evenly to the entire burn wound, until the ointment completely covers the wound and extends 0.5cm beyond the edge of the wound. The thickness of the ointment should be 1-2mm. For blisters and areas with poor healing, the thickness should be increased as appropriate.

[0033] Dosage frequency: twice daily.

[0034] Treatment results: After 5 days of medication, the pain was relieved, the blisters completely dried up, and the scabs began to fall off naturally; after 7 days of medication, the scabs completely fell off, and the wound was basically healed; after 11 days of medication, the wound was healed.

[0035] Test Example 4 like Figures 29 to 38 As shown: Ms. Nu, 49 years old, accidentally suffered scalds to her anterior shin and ulnar side of her right forearm with boiling water two weeks before seeking medical attention. She applied toothpaste on the day of the scald without effect. From the second day after the scald until her visit, she applied ointment on her own, but there was no significant improvement. The assessment was superficial second degree, with blisters and pain. When she sought medical attention, the blisters had ruptured, and there was still exudate from the wound.

[0036] Treatment regimen: Wound pretreatment: Rinse the wound with saline solution before each medication application, wipe away necrotic epidermis and secretions, and clean the wound.

[0037] Administration method: Take the burn ointment prepared using Example 1 as the raw material and apply it evenly to the entire burn wound, until the ointment completely covers the wound and extends 0.5cm beyond the edge of the wound. The thickness of the ointment should be 1-2mm. For blisters and areas with poor healing, the thickness should be increased as appropriate.

[0038] Dosage frequency: twice daily.

[0039] Treatment results: After 2 days of medication, the pain was relieved, the blisters completely dried up, there was no exudate from the wound, and the scabs began to fall off naturally; after 11 days of medication, the wound healed.

[0040] The above descriptions are merely embodiments of the present invention, and common knowledge regarding specific structures and characteristics is not elaborated upon here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications will not affect the effectiveness of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A burn ointment, characterized in that, This burn ointment contains the following ingredients: Centella asiatica 15-21g, Glycyrrhiza uralensis 9-15g, Sanguisorba officinalis 9-15g, Lithospermum erythrorhizon 18-24g, Polygonum cuspidatum 6-12g, Rheum palmatum 21-27g, Coptis chinensis 3-9g, Bletilla striata 9-15g, Horse oil 350-450g, and Beeswax 46-60g.

2. A method for preparing a burn ointment, characterized in that, Includes the following steps: S1. Pre-treatment of medicinal materials: First, all medicinal materials are washed, and then dried using different methods according to the characteristics of different medicinal materials. S2. Herbal powdering: After all the herbs are dried, they are pulverized using a universal pulverizer. The pulverized powder is then sieved through a No. 2-4 pharmacopoeia sieve 1-2 times. S3. Soaking the medicinal powder: Add horse oil to a water bath at a constant temperature of 40℃. The total mass ratio of horse oil to medicinal powder is 4:

1. Then add all the sieved medicinal powder to the horse oil and soak for 24~48 hours to obtain medicinal oil. S4. Heating of medicinal oil and powder: After the medicinal powder has been soaked, pour the 40℃ medicinal oil and powder into a stainless steel pot and heat it continuously on the lowest flame of the gas stove. The final oil temperature is controlled at 110~130℃. The time from putting the medicinal materials into the pot to taking them out is 60~90 minutes. When the surface of the medicinal materials is yellowish-brown, the texture is dry, and there is a medicinal aroma without a burnt smell, turn off the heat and let the oil temperature stand and cool down to 80~90℃ before removing the residue. S5. Filtration: When the oil temperature cools to 80~90℃, use a medicine spoon to scoop the medicine oil into the center of 4~8 layers of gauze in batches, place it in a container below, and let it filter by natural gravity. After the medicine oil on the gauze has flowed out and the gauze and medicine residue have cooled to room temperature, first gather the gauze around to form a gauze bag, insert a wooden stick into the gauze bag containing medicine residue, wear heat-resistant gloves and twist the gauze bag in the opposite direction to squeeze out the medicine oil from the medicine residue. The squeezed medicine oil falls into the container below. The recovery rate of the medicine oil squeezed out of the medicine residue is 10% of the medicine oil. S6. Formulation: After the medicated oil has cooled to 50°C, add white beeswax and heat to 70-80°C. The mass ratio of beeswax to medicated oil is 2:

15. Stir 2-4 times per minute for 5 minutes until the liquid is uniform in color, free of flocculent matter or sediment, has a medicinal aroma without a burnt smell, and feels smooth and granular when stirred. Then cool the medicated oil to 60-70°C. While the medicated oil is still liquid, quickly pour it into the first strainer for initial filtration. Place a sterilized container underneath to collect the liquid. After the initial filtration, use the second strainer for secondary filtration until all the medicated oil is drained. Then allow it to cool naturally until it solidifies to obtain the finished burn ointment.

3. The method for preparing a burn ointment according to claim 2, characterized in that, In S1, the cleaning method for medicinal materials is as follows: rhubarb, burnet root, Japanese knotweed, coptis root, licorice, purple gromwell root and white yam should be gently brushed with a soft brush under running water to wash the dirt in the pits on the surface. White yam is rich in mucilage and easily becomes sticky after absorbing water, so it should be washed and taken out immediately. Purple gromwell is easily stained, so do not rub it vigorously. Centella asiatica is relatively soft, so when washing it, put it in a basin and stir it gently to let the mud and sand settle. Use a strainer to scoop it out and then rinse it under running water.

4. The method for preparing a burn ointment according to claim 2, characterized in that, In S1, the drying methods for medicinal materials are as follows: Polygonum cuspidatum is dried in hot air at 60℃ for 7 hours, with a spread thickness of 3±0.5mm, and turned once during the process. After drying, the moisture content is less than 5%. Bletilla striata is dried in hot air at 60℃ until the moisture content is 40%, then sliced, and then dried in hot air at 60℃ until the moisture content is less than 12%. Coptis chinensis is dried in hot air at 60℃ for 3~5 hours until the moisture content is less than 12%. Rheum palmatum is baked in two stages in hot air at 60~70℃ until the moisture content is less than 15%. After cooling, Centella asiatica is dried in hot air at 50-110℃ for 1-2 hours; Glycyrrhiza uralensis is dried in hot air at 60-70℃ for 4-5 hours until the moisture content is below 12%; Sanguisorba officinalis is dried in hot air at 60℃ until it makes a crisp sound when broken, and the moisture content after drying is below 14%; Lithospermum erythrorhizon is cut into thick slices and sun-dried until the moisture content after sun-drying is below 15%.

5. The method for preparing a burn ointment according to claim 4, characterized in that, The specific method for the two-stage drying of rhubarb is as follows: The first stage is at a temperature of 50-60℃ and a drying time of 12-24 hours, until the surface of the rhubarb is noticeably wrinkled, slightly hardened, not easily deformed by hand, and the cross-section begins to darken in color. Then, remove the rhubarb and spread it out to cool for 12-24 hours. After cooling, proceed with the second stage of drying at a temperature of 60-70℃ for 24-48 hours, turning it over every 4-6 hours during this period, until the cross-section of the rhubarb is uniform in color, firm in texture, and produces a crisp sound when tapped. After drying, remove the rhubarb, spread it out to cool to room temperature, and then pack it in bags for storage.

6. The method for preparing a burn ointment according to claim 2, characterized in that, In S4, the medicinal oil and powder are heated from the initial temperature of 40℃ to 110~130℃ in 8~15 minutes, during which the temperature is measured once every minute and the mixture is manually stirred 2~4 times per minute.

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