Chinese herbal medicine powder for treating gout and preparation method thereof

Abstract

The present invention belongs to the field of Chinese herbal medicine, and provides a Chinese herbal medicine powder for treating gout and a preparation method thereof. The traditional Chinese medicine powder comprises the following raw materials in parts by weight: 90g of rhizoma atractylodis, 72g of radix paeoniae alba, 30g of caulis lonicerae, 92g of cortex phellodendri, 72g of ramulus mori, 30g of dandelion, 90g of radix salviae miltiorrhizae, 60g of fructus chaenomelis, 20g of cortex moutan, 90g of rhizoma corydalis, 60g of areca nut, 20g of rhizoma alismatis, 90g of liquidambar formosana hance, 36g of radix cyathulae, 30g of radix stephaniae tetrandrae, 90g of poria, 18g of rhizoma cimicifugae, 30g of semen coicis, 150g of pine nodular branch, 54g of faeces trogopterori, 30g of radix rehmanniae preparata, 72g of silkworm excrement, 18g of licorice, 30g of fructus lycii, 30g of goat horn leaf, 30g of herba cynomorii, 50g of radix codonopsis, 20g of radix scutellariae, 30g of pinellia ternata and 30g of bulbus fritillariae thunbergii; the Chinese herbal medicine powder prepared by the present invention can significantly reduce the pain degree of gout patients, reduce the swelling degree of joints, and also improve the uric acid level to greatly lower the uric acid level. Compared with the existing drugs for treating gout, it has better therapeutic effect, and all the medicinal materials adopted by the present invention are pure natural, which have no side effects on the human body.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine, specifically a traditional Chinese medicine powder for treating gout and its preparation method. Background Technology

[0002] Gout is a disease caused by abnormal uric acid metabolism, mainly manifested as joint pain, redness, and swelling. In severe cases, it can lead to joint deformities and functional impairment, greatly affecting the patient's quality of life. Uric acid is the end product of purine metabolism. When there is excessive production or reduced excretion of uric acid in the body, it leads to elevated blood uric acid levels, which in turn forms urate crystals that deposit in joints, soft tissues, and other areas, causing inflammatory reactions and tissue damage.

[0003] Currently, in the field of traditional Chinese medicine, some medicinal materials with the effects of promoting diuresis and removing dampness, promoting blood circulation and removing blood stasis, and clearing heat and detoxifying are used to treat gout and have achieved certain therapeutic effects. However, traditional Chinese medicine treatment for gout often uses methods such as decoction or soaking, which results in incomplete extraction of medicinal components and low drug utilization. At the same time, the differences in medicinal properties between medicinal materials also lead to drug interactions, affecting the treatment effect and making the treatment effect unsatisfactory.

[0004] To address the problems raised in the background art, those skilled in the art have proposed a traditional Chinese medicine powder for treating gout and its preparation method. Summary of the Invention

[0005] To address the aforementioned technical problems, this invention provides a traditional Chinese medicine powder for treating gout and its preparation method, thereby resolving the issues in the prior art.

[0006] A traditional Chinese medicine powder for treating gout comprises the following ingredients in parts by weight: Atractylodes lancea 90g, Paeonia lactiflora 72g, Lonicera japonica vine 30g, Phellodendron chinense 92g, Morus alba twig 72g, Taraxacum mongolicum 30g, Salvia miltiorrhiza 90g, Chaenomeles speciosa 60g, Paeonia suffruticosa 20g, Corydalis yanhusuo 90g, Areca catechu 60g, Alisma plantago-aquatica 20g, Liquidambar formosana 90g, Achyranthes bidentata 36g, Stephania tetrandra 30g, Poria cocos 90g, Cimicifuga foetida 18g, Coix lacryma-jobi 30g, Pinus massoniana 150g, Trogopterus xanthipes 54g, Rehmannia glutinosa 30g, Bombyx mori excrement 72g, Glycyrrhiza uralensis 18g, Lycium barbarum 30g, Rheum palmatum leaf 30g, Cynomorium songaricum 30g, Codonopsis pilosula 50g, Scutellaria baicalensis 20g, Pinellia ternata 30g, and Fritillaria thunbergii 30g.

[0007] A method for preparing a traditional Chinese medicine powder for treating gout includes the following steps:

[0008] S1. Raw material pretreatment;

[0009] S2, Raw material grading;

[0010] S3. Extraction and consolidation of raw material extracts;

[0011] S4. Dry the combined extracts to obtain a dry powder;

[0012] S5. Dry powder sieving process;

[0013] S6. Finished product inspection and packaging.

[0014] Preferably, in step S1, the raw material pretreatment includes the following steps:

[0015] S11. Raw material selection: Select qualified raw materials for each component.

[0016] S12. Raw material cleaning: Soak each component raw material in clean water for 25-30 minutes and gently rub and wash to remove attached dust and pesticide residues.

[0017] S13. Raw material cutting: After cleaning, each component of the raw material is cut to increase its surface area.

[0018] S14. Raw material drying: The cut raw materials are air-dried at 40-45℃.

[0019] Preferably, in step S2, the raw material grading includes classifying the raw materials into light medicinal materials and heat-resistant medicinal materials. The light medicinal materials are Atractylodes lancea, Paeonia lactiflora, Lonicera japonica, Glycyrrhiza uralensis, pine resin, mulberry twigs, Taraxacum mongolicum, Paeonia suffruticosa, Achyranthes bidentata, Stephania tetrandra, Coix lacryma-jobi, Rehmannia glutinosa, Lycium barbarum, Rheum palmatum leaves, and Cynomorium songaricum. The heat-resistant medicinal materials are Phellodendron chinense, Salvia miltiorrhiza, Chaenomeles speciosa, Corydalis yanhusuo, Areca catechu, Alisma plantago-aquatica, Liquidambar formosana, Trogopterus xanthipes, Bombyx mori excrement, Cimicifuga foetida, Poria cocos, Codonopsis pilosula, Scutellaria baicalensis, Pinellia ternata, and Fritillaria thunbergii.

[0020] Preferably, in step S3, the extraction and merging of the raw material extract includes the following steps:

[0021] S31. Soak the light medicinal materials in cold water for 4-5 hours, then filter to obtain extract A for later use.

[0022] S32. Extract the heat-resistant medicinal materials by boiling them in hot water. The amount of water should be 6 times the weight of the medicinal materials. After heating for 30-35 minutes, filter the solution and collect the extract B for later use.

[0023] S33. Mix extract A and extract B to obtain mixed extract C.

[0024] Preferably, in step S4, the extract C is converted into dry powder using a spray dryer, and the hot air inlet temperature of the dryer is controlled at 150-180℃. The model of the spray dryer is B-290.

[0025] Preferably, in step S5, the dry powder sieving process includes using a 40-mesh sieve to sieve the dried powder to remove large particles and impurities, ensuring that the powder is uniform and fine.

[0026] Preferably, in step S6, the finished product inspection and packaging includes testing the active ingredients, heavy metals and microorganisms of the Chinese herbal medicine powder, and packaging it after it passes the test.

[0027] Compared with the prior art, the present invention has the following beneficial effects:

[0028] 1. The herbal powder prepared by this invention can significantly reduce the pain level of gout patients, reduce joint swelling, and improve uric acid levels, thus greatly reducing uric acid levels. It has a better therapeutic effect than existing gout treatments. Moreover, the herbs used in this invention are all pure natural medicinal materials and have no side effects on the human body.

[0029] 2. In the preparation method of the present invention, by classifying the raw materials into lightweight medicinal materials and heat-resistant medicinal materials, different extraction methods can be adopted for different types of medicinal materials, thereby improving the extraction effect and efficiency, and improving the consistency and quality of the product. Attached Figure Description

[0030] Figure 1 This is a flowchart illustrating the preparation process of the herbal powder of the present invention. Detailed Implementation

[0031] The embodiments of the present invention will be described in further detail below with reference to the accompanying drawings and examples. The following examples are for illustrative purposes only and should not be construed as limiting the scope of the invention.

[0032] like Figure 1 As shown:

[0033] Example 1: This invention provides a traditional Chinese medicine powder for treating gout, comprising the following ingredients by weight: Atractylodes lancea 90g, Paeonia lactiflora 72g, Lonicera japonica vine 30g, Phellodendron chinense 92g, Morus alba twig 72g, Taraxacum mongolicum 30g, Salvia miltiorrhiza 90g, Chaenomeles speciosa 60g, Paeonia suffruticosa 20g, Corydalis yanhusuo 90g, Areca catechu 60g, Alisma plantago-aquatica 20g, Liquidambar formosana 90g, Achyranthes bidentata 36g, Stephania tetrandra 30g, Poria cocos 90g, Cimicifuga foetida 18g, Coix lacryma-jobi 30g, Pinus massoniana 150g, Trogopterus xanthipes 54g, Rehmannia glutinosa 30g, Bombyx mori excrement 72g, Glycyrrhiza uralensis 18g, Lycium barbarum 30g, Rheum palmatum leaf 30g, Cynomorium songaricum 30g, Codonopsis pilosula 50g, Scutellaria baicalensis 20g, Pinellia ternata 30g, and Fritillaria thunbergii 30g.

[0034] Among them, Alisma plantago-aquatica, Coix lacryma-jobi, and Atractylodes lancea have significant diuretic and dampness-removing effects, which can help eliminate excess water and uric acid from the body and reduce joint swelling and pain caused by excessive dampness. Taraxacum mongolicum and Liquidambar formosana also help to clear the meridians and promote diuresis, further promoting the excretion of damp heat.

[0035] The three herbs, Danshen, Yuanhu, and Wulingzhi, can promote blood circulation and remove blood stasis, which can help improve blood circulation and relieve pain and swelling caused by gout. Baishao can both promote blood circulation and moderate the properties of other herbs, which can reduce the mutual stimulation between drugs.

[0036] Phellodendron bark, Scutellaria baicalensis, and Cimicifuga rhizome have the effects of clearing heat and detoxifying, which can help reduce inflammation and are suitable for patients with damp-heat type gout. Honeysuckle vine also has the effect of clearing heat and detoxifying, which can relieve pain by reducing the inflammatory response in the body.

[0037] Corydalis rhizome, peony bark, and five-spice powder have good analgesic effects and are suitable for relieving joint pain caused by gout attacks. Fangji (Stephania tetrandra) has anti-inflammatory and analgesic effects and can be combined with other medicinal materials to reduce pain.

[0038] Codonopsis pilosula, licorice, and Rehmannia glutinosa can enhance immunity and physical strength, improve the patient's overall tolerance during treatment, and are suitable for patients with deficiency of both qi and blood. Goji berries help improve kidney function and further support the generation of qi and blood.

[0039] Mulberry twigs and ginseng have certain anti-inflammatory effects and can help relieve joint inflammation caused by gout. Turpentine can promote local blood circulation and has anti-inflammatory and analgesic effects.

[0040] Licorice can harmonize the properties of various medicinal materials, reduce potential side effects, and enhance the overall effect of the prescription.

[0041] Danshen and Rehmannia glutinosa can help with liver and kidney function. The kidneys are the main site for uric acid excretion, and improving kidney function helps to lower uric acid levels in the body.

[0042] Example 2: This example is basically the same as the previous example, except that a method for preparing a traditional Chinese medicine powder for treating gout includes the following steps:

[0043] S1. Raw material pretreatment;

[0044] S2, Raw material grading;

[0045] S3. Extraction and consolidation of raw material extracts;

[0046] S4. Dry the combined extracts to obtain a dry powder;

[0047] S5. Dry powder sieving process;

[0048] S6. Finished product inspection and packaging.

[0049] Furthermore, in step S1, the raw material pretreatment includes the following steps:

[0050] S11. Raw material selection: Select qualified raw materials for each component.

[0051] S12. Raw material cleaning: Soak each component raw material in clean water for 25-30 minutes and gently rub and wash to remove attached dust and pesticide residues.

[0052] S13. Raw material cutting: After cleaning, each component of the raw material is cut to increase its surface area.

[0053] S14. Raw material drying: The cut raw materials are air-dried at 40-45℃.

[0054] Among these methods, selecting qualified raw materials ensures the safety and effectiveness of the final product, reducing the health risks that may be caused by unqualified raw materials. Soaking and washing remove attached dust and pesticide residues, ensuring the cleanliness of the raw materials and reducing potential harm to human health. Cutting the raw materials increases their surface area, which helps to improve the efficiency of subsequent extraction, making it easier for active ingredients to dissolve into the extract and improving the extraction effect. Air drying at a temperature of 40-45℃ preserves the active ingredients in the raw materials, avoids degradation of effective ingredients caused by high temperatures, and ensures the extraction effect.

[0055] Furthermore, in step S2, the raw material grading includes classifying the raw materials into light medicinal materials and heat-resistant medicinal materials. The light medicinal materials are Atractylodes lancea, Paeonia lactiflora, Lonicera japonica, Glycyrrhiza uralensis, pine resin, mulberry twigs, Taraxacum mongolicum, Paeonia suffruticosa, Achyranthes bidentata, Stephania tetrandra, Coix lacryma-jobi, Rehmannia glutinosa, Lycium barbarum, Rheum palmatum leaves, and Cynomorium songaricum. The heat-resistant medicinal materials are Phellodendron chinense, Salvia miltiorrhiza, Chaenomeles speciosa, Corydalis yanhusuo, Areca catechu, Alisma plantago-aquatica, Liquidambar formosana, Trogopterus xanthipes, Bombyx mori excrement, Cimicifuga foetida, Poria cocos, Codonopsis pilosula, Scutellaria baicalensis, Pinellia ternata, and Fritillaria thunbergii.

[0056] By classifying the raw materials into lightweight medicinal materials and heat-resistant medicinal materials, different extraction methods can be used for different types of medicinal materials, thereby improving the extraction effect and efficiency, and enhancing the consistency and quality of the products.

[0057] Furthermore, in step S3, the extraction and merging of the raw material extract includes the following steps:

[0058] S31. Soak the light medicinal materials in cold water for 4-5 hours, then filter to obtain extract A for later use.

[0059] S32. Extract the heat-resistant medicinal materials by boiling them in hot water. The amount of water should be 6 times the weight of the medicinal materials. After heating for 30-35 minutes, filter the solution and collect the extract B for later use.

[0060] S33. Mix extract A and extract B to obtain mixed extract C.

[0061] By using cold water soaking to extract light medicinal materials, water-soluble components can be fully extracted. The process is gentle and can maintain the stability of the active ingredients in light medicinal materials.

[0062] Extraction by boiling in hot water effectively releases the active ingredients of heat-resistant medicinal materials, improving the comprehensiveness of the extraction and ensuring the acquisition of abundant active ingredients.

[0063] Combining extract A and extract B helps to integrate the advantages of lightweight and heat-resistant medicinal materials, forming a solution that comprehensively extracts and balances active ingredients, thereby improving the overall efficacy.

[0064] Furthermore, in step S4, the extract C is converted into dry powder using a spray dryer, with the hot air inlet temperature of the dryer controlled at 150-180℃.

[0065] By using a spray dryer, the extract can be quickly converted into dry powder, effectively preventing the degradation of active ingredients while maintaining the product's fluidity and ease of storage.

[0066] Furthermore, in step S5, the dry powder sieving process includes using a 40-mesh sieve to sieve the dried powder to remove large particles and impurities.

[0067] By removing large particles and impurities through sieving, the purity and uniformity of the dry powder can be improved, ensuring the effectiveness and quality stability of subsequent use.

[0068] Furthermore, in step S6, the finished product inspection and packaging includes testing the active ingredients, heavy metals, and microorganisms of the Chinese herbal medicine powder, and packaging it after it passes the test.

[0069] Experimental example:

[0070] Ten gout patients were randomly divided into two groups (experimental group and control group), with five patients in each group. The experimental group took the herbal powder for treating gout provided by this invention. The method of administration was to pour the powder directly into hot water, stir well, and drink it twice a day. The control group took common gout treatment drugs on the market. The two groups were tested for one month. During the experiment, various data of the patients were recorded. The results are shown in Table 1 (experimental group) and Table 2 (control group).

[0071] Table 1

[0072]

[0073]

[0074] Table 2

[0075]

[0076] In Tables 1 and 2 above, the pain level is assessed on a 10-point scale, with higher scores indicating higher pain levels.

[0077] As shown in Tables 1 and 2 above, the pain level, joint swelling level, and uric acid level of the experimental group patients after one month of treatment were significantly improved compared with those of the control group after one month of treatment. This indicates that the herbal powder of this invention can significantly reduce the pain level and joint swelling of gout patients, while also improving uric acid levels, resulting in a significant reduction in uric acid levels. It has a better therapeutic effect than existing gout medications, and the herbs used in this invention are all pure natural medicinal materials with no side effects on the human body.

[0078] The embodiments of the present invention are given for the purposes of illustration and description. Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A traditional Chinese medicine powder for treating gout, characterized in that: The formula consists of the following ingredients in parts by weight: Atractylodes lancea 90g, Paeonia lactiflora 72g, Lonicera japonica vine 30g, Phellodendron chinense 92g, Morus alba twig 72g, Taraxacum mongolicum 30g, Salvia miltiorrhiza 90g, Chaenomeles speciosa 60g, Paeonia suffruticosa 20g, Corydalis yanhusuo 90g, Areca catechu 60g, Alisma plantago-aquatica 20g, Liquidambar formosana 90g, Achyranthes bidentata 36g, Stephania tetrandra 30g, Poria cocos 90g, Cimicifuga foetida 18g, Coix lacryma-jobi 30g, Pinellia ternata 150g, Trogopterus xanthipes 54g, Rehmannia glutinosa 30g, Bombyx mori excrement 72g, Glycyrrhiza uralensis 18g, Lycium barbarum 30g, Rheum palmatum leaf 30g, Cynomorium songaricum 30g, Codonopsis pilosula 50g, Scutellaria baicalensis 20g, Pinellia ternata 30g, and Fritillaria thunbergii 30g.

2. A method for preparing a traditional Chinese medicine powder for treating gout, as described in claim 1, characterized in that: Includes the following steps: S1. Raw material pretreatment; S2, Raw material grading; S3. Extraction and consolidation of raw material extracts; S4. Dry the combined extracts to obtain a dry powder; S5. Dry powder sieving process; S6. Finished product inspection and packaging.

3. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S1, the raw material pretreatment includes the following steps: S11. Raw material selection: Select qualified raw materials for each component. S12. Raw material cleaning: Soak each component raw material in clean water for 25-30 minutes and gently rub and wash to remove attached dust and pesticide residues. S13. Raw material cutting: After cleaning, each component of the raw material is cut to increase its surface area. S14. Raw material drying: The cut raw materials are air-dried at 40-45℃.

4. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S2, the raw material grading includes classifying the raw materials into light medicinal materials and heat-resistant medicinal materials. The light medicinal materials are Atractylodes lancea, Paeonia lactiflora, Lonicera japonica, Glycyrrhiza uralensis, pine resin, Morus alba twigs, Taraxacum mongolicum, Paeonia suffruticosa, Achyranthes bidentata, Stephania tetrandra, Coix lacryma-jobi, Rehmannia glutinosa, Lycium barbarum, Rheum palmatum leaves, and Cynomorium songaricum. The heat-resistant medicinal materials are Phellodendron chinense, Salvia miltiorrhiza, Chaenomeles speciosa, Corydalis yanhusuo, Areca catechu, Alisma plantago-aquatica, Liquidambar formosana, Trogopterus xanthipes, Bombyx mori excrement, Cimicifuga foetida, Poria cocos, Codonopsis pilosula, Scutellaria baicalensis, Pinellia ternata, and Fritillaria thunbergii.

5. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S3, the extraction and merging of the raw material extract includes the following steps: S31. Soak the light medicinal materials in cold water for 4-5 hours, then filter to obtain extract A for later use. S32. Extract the heat-resistant medicinal materials by boiling them in hot water. The amount of water should be 6 times the weight of the medicinal materials. After heating for 30-35 minutes, filter the solution and collect the extract B for later use. S33. Mix extract A and extract B to obtain mixed extract C.

6. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S4, the extract C is converted into dry powder using a spray dryer, the model of which is B-290, and the hot air inlet temperature of the dryer is controlled at 150-180℃.

7. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S5, the dry powder sieving process includes using a 40-mesh sieve to sieve the dried powder to remove large particles and impurities.

8. The method for preparing a traditional Chinese medicine powder for treating gout as described in claim 2, characterized in that: In step S6, the finished product inspection and packaging includes testing the active ingredients, heavy metals and microorganisms of the Chinese herbal medicine powder, and packaging it after it passes the test.

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