Traditional Chinese medicine for treating hemorrhoids and preparation method thereof

Abstract

The present application relates to the field of medicine, specifically refers to a kind of traditional Chinese medicine for treating hemorrhoids and preparation method thereof.The present application uses heavy use of coix seed as monarch, uses spleen to restore the basis of spleen and stomach transportation and transformation, removes wet to remove the wet that has been generated, protects the middle state, cuts off the source of wet heat, phlegm stasis, turbidity toxin generation;Subordinate to three seven stasis removing and collateral dredging, prunus mume softens and astringes membrane, to remove wetness obstruction secondary stasis, hyperplasia of fibrous tissue;With silkworm chrysalis phlegm resolving and knot breaking, white yam protects membrane and astringes sore, and with chaulmoogra to remove long stagnation turbidity, dissipate stubborn hemorrhoids;The whole prescription is compatible and jointly plays the effect of spleen and wetness, stasis and phlegm resolving, detoxification and hemorrhoid, astringes sore and hemostasis, not only can quickly relieve swelling and pain, and effectively eliminate hyperplastic lesions, for hemorrhoids, especially hyperplastic hemorrhoids, fibrosis hemorrhoids, etc.Effectively treat, can effectively treat hyperplastic hemorrhoids erosion, rubbing and ulceration caused by repeated bleeding, hemostasis and can eliminate hyperplastic lesions, treat the root and the branch.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical technology, specifically to a traditional Chinese medicine for treating hemorrhoids and its preparation method. Background Technology

[0002] Hemorrhoids are a common condition located in the anal area, and are classified into internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids depending on their location. The clinical manifestations of sores include anal itching, swelling and pain, bleeding, and even ulceration.

[0003] Western medicine treatments for hemorrhoids mainly include surgical methods, cryotherapy and hyperthermia, banding and ligation, and injection therapy. These treatments are expensive, have long recovery periods, and are prone to complications. Traditional Chinese medicine (TCM) treatment for hemorrhoids has advantages such as significant efficacy, addressing both the symptoms and the root cause, and fewer drug side effects, leading to its rapid application and promotion in the field of hemorrhoid disease. However, traditional Chinese medicine often treats hemorrhoids based on the principles of wind-heat in the intestines, damp-heat accumulation, and qi deficiency, and clinically uses blood-cooling and hemostatic drugs such as Sanguisorba officinalis, Sophora japonica, and Sophora japonica fruit to improve acute rectal bleeding and anal swelling and pain. However, existing Chinese patent medicines and traditional prescriptions generally only improve the symptoms of inflammation, bleeding, and edema in the acute phase of hemorrhoids, and cannot effectively dissipate the fibrosis and hyperplastic hemorrhoids formed by long-term recurrent attacks. Clinically, patients with chronic mixed hemorrhoids, connective tissue external hemorrhoids, thrombosed hemorrhoids with organized hardening, postoperative residual hemorrhoids, and hyperplastic and hypertrophic hemorrhoids with erosion and bleeding generally have the characteristics of persistent hemorrhoid hyperplasia, repeated ulceration and bleeding, perianal dampness and itching, and recurrence after prolonged treatment. The core pathogenesis is not simply blood heat or damp heat, but rather spleen deficiency as the root cause, with dampness, heat, phlegm, blood stasis, and turbid toxins converging and forming hemorrhoids over time. Conventional heat-clearing and blood-cooling formulas only treat the symptoms and not the root cause, making it difficult to eradicate hyperplastic hemorrhoids, resulting in an extremely high clinical recurrence rate.

[0004] Therefore, it is necessary to develop a traditional Chinese medicine that is more effective in treating hyperplastic hemorrhoids, indurated hemorrhoids, and bleeding from ruptured hemorrhoids. Summary of the Invention

[0005] Based on the above background technology, the present invention provides a traditional Chinese medicine for treating hemorrhoids and its preparation method. The present invention has a reasonable combination of ingredients and can effectively treat hemorrhoids, especially hyperplastic hemorrhoids, fibrotic hemorrhoids, and recurrent bleeding of hemorrhoids.

[0006] The technical solution of this invention: A traditional Chinese medicine for treating hemorrhoids, by weight, is composed of the following raw materials: 10-20 parts of dried plum, 5-10 parts of silkworm, 5-10 parts of Bletilla striata, 20-30 parts of Panax notoginseng, 40-50 parts of coix seed, and 1-3 parts of Brucea javanica.

[0007] Furthermore, by weight, its preparation raw materials consist of the following: 15 parts dried plum, 5 parts silkworm, 8 parts Bletilla striata, 25 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

[0008] Furthermore, by weight, its preparation raw materials consist of the following: 15 parts dried plum, 8 parts silkworm, 8 parts Bletilla striata, 22 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

[0009] Based on the same inventive concept, the present invention also provides the application of the aforementioned traditional Chinese medicine for treating hemorrhoids in the preparation of a drug for treating hemorrhoids.

[0010] Furthermore, the drug is an oral dosage form.

[0011] Furthermore, the oral dosage forms include powders, tablets, honey pills, and capsules.

[0012] Furthermore, the hemorrhoidal diseases include hyperplastic hemorrhoids, fibrotic hemorrhoids, and hemorrhoidal bleeding.

[0013] Furthermore, the hemorrhoids are caused by spleen deficiency with dampness, and the accumulation of phlegm, blood stasis, and turbid toxins.

[0014] The root cause of hemorrhoids is the dysfunction of the spleen and stomach in transporting and transforming nutrients, leading to the internal generation of dampness. Dampness tends to descend and accumulate at the anus. Over time, dampness transforms into heat, which steams the perianal blood vessels, causing stagnation of qi and blood, and blood stasis. Dampness and blood stasis obstruct the distribution of body fluids, turning them into phlegm. Phlegm and blood stasis combine and do not disperse, forming hard hemorrhoids. The prolonged stagnation of dampness, phlegm, blood stasis, and heat generates turbid toxins, which continuously stimulate the perianal connective tissue, leading to abnormal proliferation of local tissues, forming fibrotic hemorrhoids and hardened skin tags. Turbid toxins and blood stasis erode the anal canal mucosa, damaging the blood vessels, and resulting in hemorrhoid erosion, recurrent bleeding, perianal dampness and itching, and a feeling of heaviness and a foreign body sensation.

[0015] Based on the above etiology and pathogenesis, it can be seen that the onset of this disease begins with spleen deficiency and dampness, and dampness and turbidity are the root of the generation of various evils. Based on this, the formula of this invention uses Coix seed as the principal ingredient to strengthen the spleen and restore the spleen and stomach's function of digestion and absorption, drain dampness to remove existing dampness, protect the middle jiao (spleen and stomach), and cut off the source of damp-heat, phlegm, blood stasis, and turbid toxins. The assistant ingredients are Panax notoginseng to disperse blood stasis and unblock the meridians, and Prunus mume to soften hardness and astringe the membrane, in order to eliminate secondary blood stasis and pterygium hyperplasia caused by dampness obstruction. The adjuvant ingredients are Bombyx mori to resolve phlegm and dissipate nodules, Bletilla striata to protect the membrane and astringe sores, and Brucea javanica to clear long-standing turbid toxins and dissipate stubborn hemorrhoids. The entire formula works synergistically to strengthen the spleen and drain dampness, resolve blood stasis and phlegm, detoxify and eliminate hemorrhoids, and astringe sores and stop bleeding. It can not only quickly reduce swelling and relieve pain, but also effectively eliminate hyperplastic lesions, providing effective treatment for hemorrhoids, especially hyperplastic hemorrhoids and fibrotic hemorrhoids. It can also effectively treat recurrent bleeding caused by erosion and friction ulceration of hyperplastic and hypertrophic hemorrhoids, stopping bleeding and eliminating hyperplastic lesions, treating both the symptoms and the root cause. Detailed Implementation

[0016] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0017] Example 1: A traditional Chinese medicine for treating hemorrhoids, the raw materials for its preparation are composed of the following by weight: 15 parts dried plum, 5 parts silkworm, 8 parts Bletilla striata, 25 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

[0018] Example 2: A traditional Chinese medicine for treating hemorrhoids, the raw materials for its preparation are composed of the following by weight: 15 parts dried plum, 8 parts silkworm, 8 parts Bletilla striata, 22 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

[0019] The traditional Chinese medicines in Examples 1 and 2 were prepared into oral medications for oral administration. The following describes the preparation of capsules, including the following steps: 1) Processing of Brucea javanica Take the kernels of Brucea javanica, remove the outer shell and impurities; Low-temperature processing with wheat bran is used, with the temperature controlled at 90-110℃. Stir-fry over medium heat until the kernels of Brucea javanica are slightly wrinkled and slightly yellow in color. Sift out the wheat bran and let cool. After processing, the kernels of Brucea javanica are lightly defatted to remove excessive irritating Brucea javanica oil and retain the effective nodule-dispersing components. Then, they are crushed and passed through an 80-mesh sieve. 2) The remaining five medicinal materials are cleaned, dried, and routinely pulverized before being passed through an 80-mesh sieve; 3) After thoroughly mixing the powders of Brucea javanica, Coix lacryma-jobi, Panax notoginseng, Prunus mume, Bletilla striata, and Bombyx mori, fill the capsule shells with 0.5g of the powders into each capsule.

[0020] Contraindications and precautions of the traditional Chinese medicines in Examples 1 and 2 1. Not for use by pregnant women, breastfeeding women, or children; 2. This product is contraindicated for those with spleen and stomach deficiency and cold, long-term loose stools, digestive tract ulcers, or abnormal liver and kidney function.

[0021] 3. This product is not suitable for use alone by those without hyperplastic hemorrhoids or those with rectal prolapse due to qi deficiency.

[0022] From 2024 to 2025, this invention was applied to treat hundreds of hemorrhoid patients, with over 72% reporting significant treatment effects (disappearance of rectal bleeding, basic relief of distension, dampness, and itching; significant softening and reduction in size of hemorrhoid nodules, repair of mucosal erosion, and basic control of symptoms, with only slight discomfort after exertion). The following is a typical case of treating hemorrhoids with traditional Chinese medicine according to the present invention.

[0023] Case 1: Mr. Li, 46 years old, male, with a 6-year history of chronic mixed hemorrhoids. Chief symptoms: prolapsed hemorrhoids during defecation, which could be reduced afterward; recurrent bleeding on toilet paper; persistent anal distension; and a sticky, moist perianal area, which worsened with fatigue and spicy food. Tongue and pulse: swollen tongue, dark in color, with a thick, greasy yellow coating; pulse was soft and hesitant. Anoscopy revealed erosion of the internal hemorrhoid mucosa and fibrotic hyperplasia of the hemorrhoids. The diagnosis was spleen deficiency with dampness, and phlegm, blood stasis, and turbid toxin accumulation. After taking the traditional Chinese medicine from Example 1 for 9 consecutive days (2 capsules twice daily), the rectal bleeding disappeared, the distension and dampness subsided, and the hemorrhoids significantly shrank.

[0024] Case 2: Ms. Han, 52 years old, female, had been suffering from connective tissue external hemorrhoids for 8 years due to postpartum complications. Chief symptoms: Multiple skin tags proliferating around the anus, without significant severe pain, but with recurring perianal dampness and itching, and sticky, unsatisfactory bowel movements. Tongue and pulse: Swollen tongue with a thick, greasy coating, and a slippery, weak pulse. Diagnosis: Spleen deficiency with dampness accumulation and turbid toxin accumulation. After taking the traditional Chinese medicine from Example 1 for 10 consecutive days (2 capsules twice daily), the perianal exudation and itching were significantly relieved, and the proliferating skin tags softened and shrank.

[0025] Case 3: Mr. Cai, 38 years old, male, in the recovery period after conservative treatment for thrombosed external hemorrhoids. Chief symptom: Residual hard fibrotic nodules at the anal margin for over 3 months; significant anal distension and foreign body sensation after prolonged sitting or standing; no significant severe pain; occasional perianal dampness. Tongue and pulse: Dark tongue with petechiae and greasy coating; slippery and choppy pulse. Diagnosis: Damp-phlegm stagnation and blood stasis, with stagnant hard nodules. After taking the traditional Chinese medicine from Example 1 for 8 consecutive days (2 capsules twice daily), the hard nodules gradually softened and subsided, and the distension sensation after prolonged sitting was completely relieved.

[0026] Case 4: Mr. Tang, 34 years old, male, had suffered from stage II hyperplastic internal hemorrhoids for many years. Chief symptoms: dry, sticky stools; prolapsed hemorrhoids during defecation, which would spontaneously retract afterward; intermittent bright red rectal bleeding; slight anal distension and dampness. Tongue and pulse: pale, swollen tongue with a yellow, greasy coating; soft, hesitant pulse. Diagnosis: Spleen deficiency with dampness obstruction and blood stasis leading to hemorrhoid formation. After taking the traditional Chinese medicine from Example 1 for 7 days (2 capsules twice daily), the bleeding stopped, the frequency of hemorrhoid prolapse decreased significantly, and the perianal dampness disappeared.

[0027] Case 5: Ms. Han, 41 years old, female, with recurrent inflammatory mixed hemorrhoids. Chief symptoms: swelling and pain in hemorrhoids after eating spicy food or staying up late, with intestinal fluid leakage and perianal dampness. Recurrent episodes, easily recurring with conventional topical medications, and progressive hardening and enlargement of the hemorrhoids. Tongue and pulse: dark red tongue with a yellow, greasy coating; slippery and rapid pulse. Diagnosis: prolonged damp-heat stagnation, phlegm-blood stasis, and turbid toxin accumulation. After taking the traditional Chinese medicine from Example 1 for 9 consecutive days (2 capsules twice daily), the inflammation completely subsided, the persistent enlargement of the hemorrhoids was controlled, and the recurrence rate significantly decreased.

[0028] Case 6: Mr. Ding, 50 years old, male, 4 months post-operatively for circumferential mixed hemorrhoids, with residual hyperplastic hemorrhoids. Chief symptoms: The wound had healed, but multiple small hyperplastic nodules remained inside the anus, a persistent feeling of a foreign body and pressure in the anus, occasional blood on toilet paper, and slight dampness around the anus. Tongue and pulse: Dark tongue with a greasy coating, and a soft, hesitant pulse. Diagnosis: Post-operative dampness and blood stasis not cleared, with residual toxins forming hemorrhoids. He continued taking the traditional Chinese medicine from Example 2 for 10 days (2 capsules twice a day, morning and evening). The foreign body sensation in the anus disappeared, the residual hyperplastic nodules softened and subsided, and there was no further bleeding.

[0029] Case 7: Mr. Zhu, 55 years old, male, presented with ruptured and bleeding hemorrhoids. Chief symptoms: enlarged and hard hemorrhoids within the anus, repeated dripping blood after defecation friction, slow wound healing, perianal dampness and stickiness, and anal distension. Tongue and pulse: Dark purple tongue with a thick, greasy yellow coating; deep, hesitant pulse. Diagnosis: Spleen deficiency with dampness, phlegm-stasis-turbidity toxin eroding the collaterals and causing bleeding. Continued treatment with the traditional Chinese medicine from Example 2 for 10 days (2 capsules twice daily, morning and evening). The ruptured wound completely healed, bleeding stopped, and the congestion and edema of the hemorrhoids subsided, softening in texture.

[0030] The present invention and its embodiments have been described above. This description is not restrictive, and the embodiments shown are only one of the embodiments of the present invention. Actual implementation is not limited to this. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the present invention, they should all fall within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine for treating hemorrhoids, characterized in that, By weight, its preparation raw materials consist of the following: 10-20 parts of dried plum, 5-10 parts of silkworm, 5-10 parts of Bletilla striata, 20-30 parts of Panax notoginseng, 40-50 parts of coix seed, and 1-3 parts of Brucea javanica.

2. The traditional Chinese medicine for treating hemorrhoids according to claim 1, characterized in that, By weight, its preparation raw materials consist of the following: 15 parts dried plum, 5 parts silkworm, 8 parts Bletilla striata, 25 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

3. The traditional Chinese medicine for treating hemorrhoids according to claim 1, characterized in that, By weight, its preparation raw materials consist of the following: 15 parts dried plum, 8 parts silkworm, 8 parts Bletilla striata, 22 parts Panax notoginseng, 45 parts coix seed, and 2 parts Brucea javanica.

4. The use of the traditional Chinese medicine for treating hemorrhoids as described in claims 1 to 3 in the preparation of a medicine for treating hemorrhoids.

5. The application according to claim 4, characterized in that, The drug is an oral dosage form.

6. The application according to claim 5, characterized in that, The oral dosage forms include powders, tablets, honey pills, and capsules.

7. The application according to claim 4, characterized in that, The hemorrhoids include hyperplastic hemorrhoids, fibrotic hemorrhoids, and hemorrhoid bleeding.

8. The application according to claim 4, characterized in that, The hemorrhoids mentioned are caused by spleen deficiency with dampness, and the accumulation of phlegm, blood stasis, and turbid toxins.