A composition containing a trifluoroethyl sulfide / sulfoxide insecticide / acaricide

Abstract

The present application belongs to the field of insecticide and acaricide, and relates to a composition containing trifluoroethyl sulfide / sulfoxide acaricide. The composition contains active component A and active component B, the weight ratio of the active component A to the active component B is 1:99-99:1; the active component A is selected from compound I, and the active component B is selected from trifluoroethyl sulfide / sulfoxide acaricide; the structure of the active component A compound I is as follows, and the composition has the advantages of obvious synergistic effect and resistance delay, and can be used for preventing and treating various pests.

Description

Technical Field

[0001] This invention belongs to the field of insecticides and acaricides, and relates to a composition containing a trifluoroethyl sulfide / sulfoxide acaricide. Background Technology

[0002] In agricultural and horticultural crop production, damage caused by pests and diseases remains significant. Due to biodiversity and the simultaneous occurrence of multiple pests and diseases, the field of plant protection has a continuous need to develop new insecticides and acaricides with better activity, lower dosage, and greater environmental friendliness. Continuous use of insecticides and acaricides containing a single active ingredient in pest control easily leads to pesticide resistance in pests. Blending insecticides and acaricides with two or more active ingredients into mixed formulations plays an important role in broadening the insecticidal spectrum, controlling both pests and diseases, controlling viral diseases by controlling vector insects, reducing pesticide application costs for farmers, and delaying the development of pesticide resistance in pests. Summary of the Invention

[0003] The purpose of this invention is to provide a composition containing a trifluoroethyl sulfide / sulfoxide acaricide to meet the increasing demand for effective and constantly updated insecticides and acaricides in the fields of agricultural and forestry and urban sanitation for pest control.

[0004] The technical solution of the present invention is as follows: an insecticidal and acaricidal composition, comprising active component A and active component B, wherein the weight ratio of active component A to active component B is 1:99 to 99:1; active component A is selected from compound I, and active component B is selected from trifluoroethyl sulfide / sulfoxide acaricides; the structure of active component A, compound I, is as follows:

[0005]

[0006] In some embodiments, the active component B is selected from one or more of flufenoxuron, flupentiofenox, sulfiflumin, flufenoxuron, or betioflumin.

[0007] In some embodiments, the active component A is compound I, and the active component B is selected from one or more of Flupentiofenox or benzyldimethalin; the weight ratio of active component A to active component B is 40:1 to 1:40.

[0008] In some embodiments, active component A is compound I, and active component B is selected from Flupentiofenox or benzyldimethalin; the weight ratio of active component A to active component B is 2:1 to 1:40.

[0009] In some embodiments, active component A is compound I, and active component B is selected from Flupentiofenox or benzyldimethalin; the weight ratio between active component A and active component B is 1:1 to 1:10.

[0010] In some embodiments, the composition is mixed with a carrier and any adjuvant to form a formulation containing the composition.

[0011] The cumulative content of the active ingredient in the formulation is between 0.5% and 95%. Preferably, the cumulative content of the active ingredient in the formulation is between 1% and 85%.

[0012] Application of a composition containing a trifluoroethyl sulfide / sulfoxide acaricide, said composition for preparing an insecticide and acaricide for controlling agricultural pests or urban sanitation pests.

[0013] The above-mentioned pests are suitable for controlling various important agricultural pests, such as the carmine spider mite, hawthorn spider mite, citrus parsnip mite, citrus rust mite, apple spider mite, two-spotted spider mite, gall mite, and flour mites; and urban pests such as termites, cockroaches, ants, flies, and mosquitoes. They can be used on fruit trees such as apples, pears, citrus, and lychees; cereals such as wheat and rice; legumes such as soybeans and kidney beans; cotton; vegetables such as cabbage, cauliflower, Chinese cabbage, rapeseed, tomatoes, and peppers; and flowers. When used to control urban pests, they can be applied in homes, various public places, offices, and on trees.

[0014] Furthermore, the method of using the composition containing trifluoroethyl sulfide / sulfoxide acaricide involves applying the prepared insecticide and acaricide, in effective doses, to the pests that need to be controlled or the medium in which they grow. A commonly chosen effective dose is typically 10 to 500 grams per hectare, with a preferred effective dose of 15 to 100 grams per hectare.

[0015] The present invention has the following advantages:

[0016] 1. The composition of the present invention exhibits a significant synergistic effect on insecticidal and acaricidal activity within a certain ratio range, thereby improving the control effect of the single active ingredient compound in the composition on pests.

[0017] 2. The dosage of the composition of the present invention when applied to kill insects and mites is significantly lower than that of a single compound in the composition when used to reduce the dosage of the compound, thereby reducing the cost of use and reducing environmental pollution.

[0018] 3. The active ingredients in the composition of the present invention have different mechanisms of action in killing insects and mites, and there is no problem of cross-resistance. Using it to control pests can delay the occurrence of pesticide resistance and improve the control effect on resistant species. Detailed Implementation

[0019] The following embodiments are intended to enable those skilled in the art to more fully understand the present invention, but are not intended to limit the invention to the scope of the embodiments described.

[0020] Indoor bioactivity assay

[0021] Example 1: Determination of the synergistic effect of a composition containing compound I on the spider mite *Tetranychus cinnabarinus*.

[0022] Test subject: Tetranychus cinnabarinus Boisduval, adult mite, sensitive strain kept indoors.

[0023] Test conditions: Temperature: 24–26℃, Relative humidity: 60%, Light intensity: L:D = 14:10

[0024] Preparation of drug solution: According to different test requirements, the test samples (different ratio compositions and original drugs of the present invention) are accurately weighed using an electronic analytical balance. The original drug is dissolved in acetone and then diluted with 0.1% Tween 80 water according to the experimental design dosage to prepare a drug solution with a certain concentration.

[0025] Experimental method: The activity of the mites against adult Tetranychus carinata was determined by spraying potted seedlings. First, 40-60 adult Tetranychus carinata of uniform size were transferred to bean seedlings (leaving one true leaf) at the stage of unfolding the first pair of true leaves. After the adults stabilized, the population was counted. Then, the test material was treated with 1.5 mL of the mites using the Airbrush method. A blank control was set up.

[0026] After natural air drying, the treated test materials were placed in an observation room. The temperature, humidity, and light in the observation room could be adjusted as needed. After 72 hours, the number of live mites was investigated, and the mortality rate was calculated. The Bliss method was used for evaluation, which is one of the classic methods for evaluating the effects of mixtures. Based on his concept of independent combined action, Bliss believed that the theoretical mortality rate P of insecticides and acaricides mixed together could be calculated using the following formula:

[0027] P = Pm + Pn(1 - Pm)

[0028] Pm represents the target mortality rate (%) of the first active component at a concentration of m; Pn represents the target mortality rate (%) of the second active component at a concentration of n.

[0029] If the actual mortality rate of the target is greater than the theoretical mortality rate P after the two active components are mixed at a certain concentration, it is determined that the two active components have a synergistic effect when used together at the set concentration; otherwise, they have an antagonistic effect.

[0030] Table 1. Synergistic effect of compound I in combination with two other agents, including benzimidazole, on adult Tetranychus cinnabarinus.

[0031]

[0032]

[0033] Example 2: Indoor activity assay of the composition containing compound I against Tetranychus cinnabarinus.

[0034] The synergistic effect data above show that the combination of compound I of the present invention and two other agents, such as benzimidox, has a significant synergistic effect on adult Tetranychus cinnabarinus. Furthermore, the LC50 value and co-toxicity coefficient of the combination of compound I, benzimidox, and flupentiofenox were determined.

[0035] Test target: Adult Tetranychus cinnabarinus (boisduval) mite, a sensitive strain kept indoors.

[0036] Preparation of drug solution: According to different test requirements, the test samples are accurately weighed using an electronic analytical balance. The original drug is dissolved in acetone and then diluted with 0.1% Tween 80 water according to the experimental design dosage to form a series of drug solutions with a certain concentration gradient (the composition of this invention).

[0037] Experimental Methods: The activity of the pesticide against adult Tetranychus carinata was determined using a potted seedling spraying method. First, adult Tetranychus carinata of uniform size were transferred to bean seedlings (leaving one true leaf) at the stage of unfolding their first pair of true leaves. After the adults stabilized, the population was counted. Then, the pesticide solution was sprayed evenly using the Airbrush method, from low to high doses, at a rate of 1.5 mL per plant. Each treatment was repeated four times, with a blank control included.

[0038] The treated test materials were placed in an observation room, where the temperature, humidity, and light were adjustable as needed. The number of dead and live mites was investigated after 72 hours. The corrected mortality rate was calculated using the Abbott formula, and statistical analysis was performed using DPS data processing software to determine the toxicity regression equations, LC50 values, and 95% confidence limits for each single test agent and each combination of different ratios. The co-toxicity coefficients for each ratio were then calculated using the Sun YP method to evaluate the combined effects.

[0039] Table 2: Results of indoor combined toxicity assay of compound I and flupentiofenox against Tetranychus cinnabarinus

[0040]

[0041] Table 3. Results of indoor combined toxicity assay of compound I and benzimidazole against Tetranychus cinnabarinus.

[0042]

[0043] The results showed that the co-toxicity coefficients of compound I with benzylidene and flupentiofenox were all greater than 120, indicating that compound I has a synergistic effect with benzylidene and flupentiofenox.

Claims

1. An insecticidal and acaricidal composition, comprising active component A and active component B, wherein the weight ratio of active component A to active component B is 1:99 to 99:1; active component A is selected from compound I, and active component B is selected from trifluoroethyl sulfide / sulfoxide acaricides; the structure of active component A, compound I, is as follows:

2. The composition according to claim 1, characterized in that, The active component B is selected from one or more of flupentiofenox, sulfiflumin, flufenox, or betioflumin.

3. The composition according to claim 1, characterized in that, The active component A is compound I, and the active component B is selected from Flupentiofenox or benzyldimethalin; the weight ratio between active component A and active component B is 40:1 to 1:

40.

4. The composition according to claim 1, characterized in that, The active component A is compound I, and the active component B is selected from Flupentiofenox or benzyldimethalin; the weight ratio between active component A and active component B is 2:1 to 1:

40.

5. The composition according to claim 1, characterized in that, The active component A is compound I, and the active component B is selected from Flupentiofenox or benzyldimethalin; the weight ratio between active component A and active component B is 1:1 to 1:

10.

6. The composition according to claim 1, characterized in that, The composition is mixed with a carrier and any adjuvant to prepare a formulation containing the composition of claim 1.

7. The composition according to claim 1, characterized in that, The cumulative content of the active ingredient in the formulation is between 0.5% and 95%, preferably between 1% and 85%.

8. The application of the insecticidal and acaricidal composition according to claim 1, characterized in that, The composition is used to prepare an insecticide and acaricide for controlling agricultural pests or urban sanitation pests.

9. The application of the insecticidal and acaricidal composition according to claim 8, characterized in that, The composition is applied to the pest that needs to be controlled or the medium in which it grows, in an effective dose.

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