A light reaction device

Abstract

Provided is a photoreaction device that can easily balance the reproducibility of a photoreaction and temperature controllability. A photoreaction device for promoting a photoreaction in a reaction container includes: a main body portion; a light source portion provided on one side of the main body portion; and a heat dissipation portion provided on the other side of the main body portion opposite the one side.

Description

Technical Field

[0001] This invention relates to a photoreaction apparatus for promoting photoreactions (especially photoradical reactions) within a reaction vessel. Background Technology

[0002] In recent years, photoreactions have become an important method in fields such as organic synthesis, materials chemistry, and pharmaceuticals. These photoreactions typically take place in a reaction vessel containing starting materials, solvents, photosensitizers, and photoinitiators. When light (ultraviolet or visible light) is irradiated onto the reaction vessel, the photosensitizer, photoredox catalyst, and photoinitiator generate active species (free radicals), which react with the starting materials. Therefore, selective and efficient chemical transformation (photoreaction) of the starting materials is promoted. Furthermore, since photoreactions do not require the use of transition metal reagents, they can reduce environmental impact. Light sources used to promote these photoreactions typically include light-emitting diode (LED) lamps.

[0003] LED lights are preferred for improving photoreaction efficiency due to their advantages such as wavelength selectivity and high energy efficiency. Point-source LED lights are commonly used, but the yield of the photoreaction can fluctuate depending on factors such as the direction of the light source relative to the reaction vessel and the positional relationship between the reaction vessel and the light source. In other words, point-source LED lights suffer from low reproducibility of the photoreaction.

[0004] Furthermore, there are also photochemical devices with a structure in which a reaction chamber is surrounded by multiple light sources (e.g., Patent Document 1). The photochemical device described in Patent Document 1 includes: a reaction chamber, multiple light sources surrounding the reaction chamber, and multiple supports for housing the reaction vessel. The photochemical device in Patent Document 1 can be said to be configured for use with multi-tube bottles. This type of photochemical device is designed for small containers such as tube bottles (e.g., reaction vessels of 20 mL or less), and therefore it is difficult to say that it is suitable for medium-sized or larger containers such as flasks (e.g., reaction vessels of 30 mL or more). Therefore, there is a need for a photochemical device that can achieve excellent reproducibility of the photoreaction for general-purpose reaction vessels, including medium-sized and larger reaction vessels.

[0005] In the aforementioned photochemical device, the reaction chamber is configured to contain a temperature-controlled fluid for temperature control. This fluid is circulated through a heat exchanger into a heating and cooling unit to achieve temperature control within the reaction chamber. However, photochemical devices using this configuration for temperature control cannot be considered to possess easily controllable temperature characteristics. Therefore, a photoreaction device is needed that can easily balance the reproducibility of the photoreaction with temperature control.

[0006] Existing technical documents Patent documents Patent Document 1: Japanese Patent Publication No. 2023-537792 Summary of the Invention The problem that the invention aims to solve In view of the above-mentioned existing problems, the present invention aims to provide a photoreaction device that can easily balance the reproducibility of the photoreaction with temperature control.

[0007] Methods for solving problems This objective is achieved by the present invention described in (1) to (14) below.

[0008] (1) A photoreaction apparatus for promoting a photoreaction within a reaction vessel, comprising: Main body; The light source unit is disposed on one side of the main body unit; A heat dissipation section is provided on the opposite side of the main body.

[0009] (2) According to the light reaction device described in (1) above, the light source unit includes a plurality of LED arrays.

[0010] (3) According to the light reaction device described in (2) above, a plurality of LED arrays are arranged in a direction orthogonal to the vertical direction of the main body.

[0011] (4) According to the light reaction device described in (3) above, the plurality of LED arrays include a first LED array and a second LED array adjacent to the first LED array; The first LED array and the second LED array are offset from each other in the vertical direction of the main body.

[0012] (5) According to the light reaction device described in (1) above, the light source section includes at least a first light source region that emits light at a first wavelength and a second light source region that emits light at a second wavelength.

[0013] (6) According to the photo-reaction device described in (1) above, the heat dissipation part includes a plurality of heat dissipation fins.

[0014] (7) According to the photo-reaction device described in (6) above, a plurality of the heat dissipation fins are arranged in a direction orthogonal to the vertical direction of the main body.

[0015] (8) According to the photo-reaction device described in (7) above, the plurality of heat dissipation fins are respectively formed into strips along the vertical direction.

[0016] (9) According to the light reaction device described in (8) above, the light source unit includes an LED array arranged parallel to the vertical direction; Multiple heat dissipation fins are arranged parallel to the LED array.

[0017] (10) According to the light reaction device described in (9) above, the LED array is disposed between the plurality of heat dissipation fins and on one side of the main body.

[0018] (11) The photo-reaction device according to (6) above further includes a connecting part for connecting the main body and other devices different from the photo-reaction device; The connecting portion is disposed between the plurality of heat dissipation fins.

[0019] (12) The photo-reaction device described in (1) above further includes a foot provided on the bottom surface of the main body.

[0020] (13) According to the photo-reaction device described in (1) above, the main body has a cylindrical structure.

[0021] (14) A photoreaction device kit, comprising: the photoreaction device described in any one of (1) to (13) above; The reaction vessel is disposed adjacent to the light source section of the photoreaction device.

[0022] Invention Effects According to the present invention, a photoreaction apparatus that can easily balance the reproducibility of the photoreaction with temperature control can be provided. Attached Figure Description

[0023] Figure 1 This is a perspective view of the photoreaction device according to the first embodiment of the present invention.

[0024] Figure 2 This is a perspective view showing an example of the use of the photoreaction device according to the first embodiment of the present invention.

[0025] Figure 3 This is a top view schematically illustrating a modified example of the main body portion of the photoreaction device according to the first embodiment of the present invention.

[0026] Figure 4 This is a longitudinal sectional view schematically illustrating a modified example of the main body portion of the photoreaction device according to the first embodiment of the present invention.

[0027] Figure 5 This is a top view schematically showing the positional relationship between the light source unit and the heat dissipation unit of the photo-reaction device according to the first embodiment of the present invention.

[0028] Figure 6 This is a schematic unfolded view showing a modified example of the light source unit included in the photoreaction device according to the first embodiment of the present invention.

[0029] Figure 7 This is a schematic unfolded view showing a modified example of the heat dissipation section included in the photoreaction device according to the first embodiment of the present invention.

[0030] Figure 8 This is an enlarged view of the side portion of the photoreaction device according to the first embodiment of the present invention. (a) shows the state in which the connecting part is housed, and (b) shows the state in which the connecting part protrudes.

[0031] Figure 9 This is a perspective view schematically illustrating the photoreaction device according to the second embodiment of the present invention.

[0032] Figure 10 This is a top view schematically illustrating the photoreaction device according to the third embodiment of the present invention.

[0033] Symbol Explanation 1: Photoreaction device; 2: Main body; 3: Light source; 3A: First light source area; 3B: Second light source area; 4: Heat dissipation part; 5: Connecting part; 6: Configuration auxiliary part; 7: Space; 8: Foot; 9: Separator; 10: Reaction container; 11: Clamping part; 21: Open part; 22: Upper surface; 23: Bottom surface; 31: LED array; 41: Heat dissipation fins; 61: Hole; 62: Recess; 311: LED lamp. Detailed Implementation

[0034] <<First Embodiment>> Hereinafter, the photoreaction apparatus of the present invention will be described based on the preferred embodiments shown in the accompanying drawings. First, the first embodiment of the photoreaction apparatus of the present invention will be described. Figure 1 This is a perspective view of the photoreaction device according to the first embodiment of the present invention. Figure 2 This is a perspective view showing an example of the use of the photoreaction device according to the first embodiment of the present invention.

[0035] It should be noted that in the following descriptions, the upper side of each figure will be referred to as "upper" or "above", and the lower side will be referred to as "lower" or "below". In addition, the left side of each figure will be referred to as "left" or "left side", and the right side will be referred to as "right" or "right side".

[0036] like Figure 1 The photoreaction device 1 shown includes: a main body 2, a light source 3, a heat dissipation unit 4, a connecting part 5, and a configuration auxiliary part 6. This photoreaction device 1 is configured to promote a photoreaction in a reaction vessel 10. Specifically, in Figure 2In this example, the reaction vessel 10 is disposed inside the photoreaction apparatus 1, and the upper part of the reaction vessel 10 is fixed by the clamping part 11 of the support. The reaction vessel 10 is a 50 mL pear-shaped flask, but is not limited thereto; for example, it could also be a 1 L Erlenmeyer flask. The reaction vessel 10 contains, for example, starting materials and solvent, a photosensitizer, a photoredox catalyst, and a photoinitiator. In this state, the light source 3 irradiates light around the reaction vessel 10. Upon irradiation, the photosensitizer, photoredox catalyst, and photoinitiator absorb light energy and enter an excited state. As a result, these substances generate active species (e.g., free radicals or cations) and begin to react with the starting materials. This promotes photoreactions (photochemical reactions) such as polymerization, crosslinking, and functional group transformation. This photoreaction is only one example. The following sections will describe each part in turn.

[0037] (Main Body) The main body 2 is a cylindrical component. That is, the main body 2 has a cylindrical structure. However, the main body 2 is not limited to this; it can also be a plate-shaped component or a curved plate-shaped component, etc. Other components are disposed on the main body 2. That is, the main body 2 functions as a base for other components. A light source 3 is disposed on the inner side (one side) of the main body 2. A heat dissipation part 4 and a connecting part 5 are disposed on the outer side of the main body 2 (the other side opposite to the one side). In addition, an auxiliary part 6 is disposed on the upper side of the main body 2.

[0038] From the viewpoint of effectively utilizing the base's function, the main body 2 is preferably made of a rigid material. Examples of such rigid materials include: metallic materials, ceramic materials, composite materials such as carbon fiber reinforced plastic (CFRP), and polymeric materials such as reinforced plastics. Furthermore, the main body 2 also functions to transfer heat generated by the light source 3 to the heat dissipation part 4. From the viewpoint of effectively utilizing the heat transfer function, metallic or ceramic materials are preferred as the constituent materials of the main body 2, with metallic materials being particularly preferred.

[0039] Furthermore, the main body 2 preferably has the function of reflecting the light irradiated by the light source 3. This improves the light irradiation efficiency of the light source 3. From the viewpoint of effectively utilizing this light reflection function, the main body 2 is preferably made of a metallic or ceramic material, with a metallic material being particularly preferred.

[0040] The main body 2 is configured to surround the reaction vessel 10 ( Figure 2The light source 3 is disposed inside the main body 2, which has this surrounding structure. Therefore, the light source 3 can be easily irradiated around the reaction vessel 10, and the irradiation can be efficient and uniform. As a result, a high yield of the photoreaction can be maintained (e.g., a yield of 80% or more). Therefore, the reproducibility of the photoreaction can be improved. In other words, even if the positions of the reaction vessel 10 and the light source 3 are offset in multiple experiments (e.g., the reaction vessel 10 is located at the center of the main body 2 in the first experiment, and at the right or left end of the main body 2 in the second experiment), the yield difference between the experiments can be reduced. Thus, human-induced yield differences (yield differences caused by different distances between the reaction vessel 10 and the light source 3) can be reduced. Specifically, the yield difference can be controlled to within 5%, preferably within 3%, and more preferably within 1%. Therefore, anyone can easily conduct experiments on the photoreaction.

[0041] The enclosure structure of the main body 2 is not limited to the structure described above. The main body 2 may also not have an enclosure structure. Hereinafter, refer to... Figure 3 as well as Figure 4 A detailed explanation will be provided. Figure 3 This is a top view schematically illustrating a modified example of the main body portion of the photoreaction device according to the first embodiment of the present invention. Figure 4 This is a longitudinal sectional view schematically illustrating a modified example of the main body portion of the photoreaction device according to the first embodiment of the present invention.

[0042] first, Figure 3 The diagram schematically shows the shape of the main body 2, where the light source unit 3 is located, from a top view. For ease of explanation, other components of the light reaction device 1 (such as the heat dissipation unit 4) are omitted. Figure 3 The main body 2 shown in (a) is U-shaped from a top view. That is, the main body 2 has three inner surfaces. The light source 3 is provided on the inner side of the main body 2, i.e., on the three inner surfaces of the main body 2. In other words, Figure 3 The main body 2 shown in (a) also has an enclosing structure. The enclosing structure can improve the reproducibility of the photoreaction.

[0043] Furthermore, the main body 2 has an opening 21 formed by cutting a portion of the main body 2 along the z-axis (vertical direction). This allows heat generated by the light source 3 to dissipate through the opening 21. Therefore, the opening 21 improves the heat dissipation of the photoreactor 1 and enhances its temperature control. Moreover, the reaction vessel 10 can be easily disposed within the main body 2 not only from the top but also through the opening 21. This opening 21 can have various characteristics, such as... Figure 3The dimension shown in (a) corresponds to an inner surface, and can also have dimensions at any position such as Figure 1 The dimensions of the main body 2 when it is cut along the z-axis.

[0044] Figure 3 The main body 2 shown in (b) has a rectangular shape when viewed from above. A light source 3 is provided on one surface of the main body 2. The main body 2 does not have an enclosing structure. However, by increasing the size of the main body 2 relative to the reaction vessel 10, the light irradiation area of ​​the reaction vessel 10 can be increased. As a result, the reproducibility of the photoreaction can be ensured to a certain extent. Furthermore, in Figure 3 In the structure shown in (b), since the heat generated by the light source 3 is easily diffused to the surroundings, it can be said that the photo-reaction device 1 with the main body 2 has high temperature control.

[0045] exist Figure 3 In the variation shown in (c), Figure 3 As shown in (b) of the drawing, four main body parts 2 are assembled to form an enclosing structure. Specifically, two main body parts 2 are arranged opposite each other as their respective light source parts 3 in the left-right direction of the drawing, and two main body parts 2 are arranged opposite each other as their respective light source parts 3 in the top-bottom direction of the drawing, thus forming an enclosing structure. From Figure 3 As shown in the modified example (c), multiple main body parts 2 can be easily arranged around the reaction vessel 10 according to its shape. In other words, various surrounding structures (deformable surrounding structures) can be constructed according to the shape of the reaction vessel 10. Light irradiated by the light source part 3 can come from multiple directions (in... Figure 3 (c) The light reaches the reaction vessel 10 from four directions. As a result, the photoreaction in the reaction vessel 10 can be particularly promoted. Therefore, the reproducibility of the photoreaction can be improved. In addition, since there are gaps between the main body parts 2, the heat generated by the light source part 3 can be diffused through these gaps. Therefore, the heat dissipation of the photoreaction device 1 can be improved, and the temperature control of the photoreaction device 1 can be improved.

[0046] then, Figure 4 The cross-sectional shape of the main body 2, where the light source unit 3 is provided, is schematically shown. For ease of explanation, other components of the photoresponse device 1 (such as the heat dissipation unit 4) are omitted. Figure 4The cross-sectional shape of the main body 2 shown is approximately U-shaped. That is, the main body 2 is a cylindrical shape with a closed bottom. Therefore, light irradiated by the light source 3 can reach the reaction vessel 10 from both the bottom and the inner peripheral wall. As a result, the photoreaction in the reaction vessel 10 can be particularly promoted, and the reproducibility of the photoreaction can be particularly improved. Furthermore, the top of the main body 2 is open. As a result, the heat generated by the light source 3 can diffuse from the top, thereby improving the temperature control of the photoreaction apparatus 1.

[0047] The bottom of the main body 2 is preferably curved. In this case, even if light scattered within the inner peripheral wall or reaction vessel 10 reaches the bottom of the main body 2, the light can be reflected at the bottom because the bottom is curved, thereby effectively returning the scattered light to the reaction vessel 10. As a result, the photoreaction can be promoted efficiently.

[0048] The structure of the main body 2 is not limited to the structure described above. The main body 2 can be appropriately designed according to the size, number, shape, etc. of the reaction vessel 10. Therefore, especially when the main body 2 has an enclosing structure, the light source 3 provided inside the main body 2 can provide efficient and uniform light irradiation. As a result, the above-mentioned effects can be achieved more significantly.

[0049] (Light Source Department) Next, the light source unit 3 will be explained in detail. Figure 5 This is a top view schematically showing the positional relationship between the light source unit and the heat dissipation unit included in the photo-reaction device according to the first embodiment of the present invention. Figure 5 As shown, the light source unit 3 has a plurality of (24 in this embodiment) light-emitting diode (LED) arrays 31. That is, it has LED arrays 31 numbered 1 to 24. As a result, uniform light illumination can be easily achieved. In particular, by appropriately arranging a plurality of LED arrays 31 (for example, arranging them at equal intervals) in the main body unit 2 with the surrounding structure, uniform light illumination can be achieved across the periphery of the reaction vessel 10. Furthermore, since the light source unit 3 has a plurality of LED arrays 31, high-brightness light illumination can be achieved while suppressing overall energy consumption. As a result, efficient and uniform light illumination can be achieved, reliably promoting the photoreaction.

[0050] Each LED array 31 is composed of multiple (five in this embodiment) LED lights 311. That is, the structure formed by aligning multiple LED lights 311 is called an array structure. In this embodiment, by aligning the multiple LED lights 311 along the vertical direction (… Figure 1 Alignment along the z-axis direction in the matrix 2 forms an array structure. As a result, multiple LED arrays 31 are arranged parallel to each other on the inner circumferential surface of the main body 2. The array structure can also be formed by aligning the multiple LEDs 311 along the circumferential direction of the main body 2, or by aligning the multiple LEDs 311 along a direction orthogonal to the vertical direction (…). Figure 1 The array is formed by aligning the LEDs along the x-axis or y-axis (or other directions). This array structure allows for the distribution of heat load applied to each LED 311. As a result, overheating of the photoresponse device 1 can be suppressed or even prevented. Therefore, the light source section 3 with this structure contributes to the temperature control of the photoresponse device 1.

[0051] like Figure 1 as well as Figure 5 As shown, multiple LED arrays 31 are arranged at intervals along the inner circumferential surface of the main body 2, spanning the inner circumferential surface. That is, the multiple LED arrays 31 are arranged in a direction orthogonal to the z-axis direction of the main body 2. As a result, light can be irradiated from multiple directions, thereby efficiently promoting the light response.

[0052] Adjacent LED arrays 31 are staggered vertically. This allows for a reduction in the number of LEDs 311 contained in each LED array 31 while increasing the range of light illumination. As a result, photoreaction can be promoted particularly efficiently.

[0053] The spacing between the arrays is not particularly limited, but from the viewpoint of balancing illuminance and heat dissipation, for example, a spacing of 1 mm or more is preferred, and more preferably in the range of 1 mm to 10 mm. Furthermore, the spacing between the arrays can also be 1 cm or more. The number of arrays is not particularly limited, but preferably 2 or more, more preferably 2 or more and 60 or less, and particularly preferably 10 or more and 50 or less. Therefore, it is easy to set the spacing between the LED arrays 31 within the above-mentioned range, thereby easily balancing illuminance and heat dissipation.

[0054] The structure of LED array 31 is not limited to the structure described above. Figure 6 This is a schematic unfolded view illustrating a modified example of the light source unit included in the photoreaction apparatus according to the first embodiment of the present invention. It should be noted that... Figure 6 This involves unfolding the cylindrical main body 2 to reveal its inner side. For example... Figure 6 As shown in (a), the LED array 31 can have a ring-shaped array structure. This promotes uniform light illumination without specific directional deviation. Furthermore, as... Figure 6 As shown in (b), the LED array 31 can have an array structure that intersects the vertical direction at an angle. According to this structure, by adjusting the angle of intersection with the vertical direction, the efficiency of the light response can be improved. Furthermore, as... Figure 6 As shown in (c), the LED array 31 can also have a zigzag array structure in the vertical direction. Figure 6In the array structure shown in (c), multiple LEDs 311 are arranged alternately in a direction orthogonal to the vertical direction. This allows for improved luminous efficiency while maintaining a suitable LED density. Furthermore, these array structures also achieve the aforementioned effects.

[0055] It should be noted that in this embodiment, the light source unit 3 has multiple LED arrays 31, i.e., it has an array structure, but the present invention is not limited to this. For example, the light source unit 3 may also be composed of multiple LED lamps 311 arranged irregularly. Even with this structure, by increasing the arrangement density of the multiple LED lamps 311, the light response can be promoted. Furthermore, the light source unit 3 can be configured by appropriately selecting its type, power consumption, wavelength, etc., to obtain the desired light response.

[0056] For example, the type of light source 3 is not limited to LED, but can also be a high-pressure mercury lamp, xenon lamp, fluorescent lamp, etc. When the type of light source 3 is LED, the LED can be a monochromatic LED such as UV-LED, blue LED, or white LED, and multiple monochromatic LEDs can also be used in combination. In addition, the power consumption of the light source 3 can be 5W or more. For example, it is preferably in the range of 5W to 50W, more preferably in the range of 10W to 45W, particularly preferably in the range of 15W to 40W, and even more preferably in the range of 20W to 40W. As a result, the reproducibility of the light reaction can be reliably improved by combining the effect of the surrounding structure of the main body 2.

[0057] The wavelength of the light source 3 can be selected from the ultraviolet region (200-400 nm), the visible light region (400-700 nm), the near-infrared region (700-1000 nm), etc. As one embodiment, the wavelength of the light source 3 can be selected from 365 nm, 425 nm, 475 nm, and 525 nm. From the viewpoint of efficiently promoting the reaction, wavelengths in the ultraviolet region, represented by 375 nm, are preferred. On the other hand, from the viewpoint of suppressing side reactions, long wavelengths in the visible light region (500-700 nm), such as 525 nm, are preferred. By combining the light source 3 with wavelengths selected from the above group and the main body 2 with an enclosing structure, the aforementioned effects can be significantly achieved. As another embodiment, the multiple LEDs 311 can also emit light of different wavelengths. In this case, an independent switch can be provided for each LED 311, and switching can be performed manually or by a relay. Alternatively, switching can be performed while adjusting the light intensity of the LEDs 311 at different wavelengths using a transistor circuit or the like. These methods are just one example of controlling multiple LEDs 311; various other methods can also be used (e.g., program control of multiple LEDs 311). That is, the light source unit 3 can include a light source control unit for controlling the multiple LEDs 311. The light source control unit can, for example, be configured to control the current flowing through the aforementioned transistor-based circuit. Furthermore, the light source control unit can also be configured to control the pulse width modulation of each LED 311. With this structure, the brightness of each LED 311 can be controlled efficiently.

[0058] It should be noted that the light source unit 3 can be mounted on the inner peripheral surface of the main body 2 as a sheet component with multiple LEDs 311 pre-arranged on a predetermined sheet, or it can be directly disposed on the inner peripheral surface of the main body 2. In the former case, the sheet component can have the function of physically (structurally) combining multiple LEDs 311 with each other. The sheet component, for example, has multiple holes for inserting and fixing multiple LEDs 311. As a result, multiple LED arrays 31 with appropriately adjusted LED density can be easily obtained, and the illumination efficiency can be reliably improved. The structure of this sheet component is not particularly limited as long as it can physically (structurally) combine two or more LEDs 311.

[0059] (Heat dissipation section) The heat dissipation unit 4 has the function of dissipating the heat generated by the light irradiation of the light source unit 3 through the surrounding air (heat dissipation function). The heat dissipation unit 4 has a plurality of heat dissipation fins 41 erected in a direction orthogonal to the outer peripheral surface of the main body unit 2 (24 in this embodiment). This increases the contact area with the air (heat dissipation area). Therefore, the heat generated by the light source unit 3 can be dissipated efficiently through each heat dissipation fin 41. Therefore, the temperature rise of the photoresponse device 1 can be suppressed. As a result, the possibility of aging and failure of the photoresponse device 1 can be reduced. That is, the lifespan of the photoresponse device 1 can be suppressed.

[0060] like Figure 1 and Figure 5 As shown, multiple heat dissipation fins 41 are provided across the outer peripheral surface of the main body 2. In other words, multiple heat dissipation fins 41 are provided in a direction orthogonal to the vertical direction of the main body 2. As a result, heat generated by light irradiation from the light source 3 provided on the inner peripheral surface of the main body 2 can be efficiently dissipated from the outside of the main body 2.

[0061] Each heat dissipation fin 41 is generally plate-shaped. Specifically, the heat dissipation fin 41 is elongated and extends across the outer periphery of the main body 2 in the vertical direction. Therefore, the heat dissipation section 4 can perform its heat dissipation function by extending across the vertical direction of the main body 2. Furthermore, the thickness of the edge portion of the heat dissipation fin 41 is set to be greater than the thickness of the other portions of the heat dissipation fin 41. This allows the connecting portion 5 to be stably housed between the heat dissipation fins 41. In addition, not only can the contact area with air be further increased, but the auxiliary portion 6 can also be easily provided on each heat dissipation fin 41.

[0062] like Figure 1 as well as Figure 5 As shown, the heat dissipation fins 41 are arranged parallel to the LED array 31. That is, multiple heat dissipation fins 41 are arranged parallel to each other and along the circumference of the main body 2 on the outer peripheral surface of the main body 2. As a result, the heat generated by each of the multiple LEDs 311 included in the LED array 31 can be efficiently dissipated from the nearby heat dissipation fins 41. As a result, the temperature control of the photoresponse device 1 can be particularly improved.

[0063] While the number of heat dissipation fins 41 is not particularly limited, it is preferably 2 or more, more preferably 2 or more but less than 60, and particularly preferably 10 or more but less than 50. This allows for effective heat dissipation. In particular, when the number of LED arrays 31 is approximately equal to (preferably the same as) the number of heat dissipation fins 41, it is easy to balance luminous efficiency and heat dissipation.

[0064] Adjacent heat dissipation fins 41 are spaced apart from each other at a predetermined distance. This predetermined distance (gap) is not particularly limited, and can be, for example, 0.5cm to 10cm, preferably in the range of 1cm to 5cm. This allows the heat dissipation unit 4 to function effectively. Furthermore, an LED array 31 is provided on the inner circumferential surface of the main body 2 at the midpoint of the predetermined distance. Figure 5 That is, adjacent heat dissipation fins 41 are provided with LED arrays 31 on the inner peripheral surface of the main body 2. In this way, in the heat dissipation section 4, two heat dissipation fins 41 are adjacent to one LED array 31. Through the adjacent structure of the heat dissipation section 4, the heat from the LED array 31 can be efficiently dissipated through the two heat dissipation fins 41, thereby improving the temperature control of the photoresponse device 1.

[0065] Furthermore, due to the space 7 formed between the heat dissipation fins 41 ( Figure 8 Therefore, the heat from the LED array 31 can be efficiently dissipated through the air in space 7. Thus, the aforementioned effects can be achieved more significantly.

[0066] The configuration of the heat dissipation fins 41 may not be limited to the configuration described above. See below for reference. Figure 7 A detailed explanation will be provided. Figure 7 This is a schematic unfolded view illustrating a modified example of the heat dissipation unit included in the photoreaction device according to the first embodiment of the present invention. It should be noted that... Figure 7 Show the cylindrical main body 2, showing its outer side.

[0067] like Figure 7 As shown in (a), the heat dissipation fins 41 can be arranged parallel to each other along the circumference of the main body 2 in the z-axis direction. This improves lateral airflow (increases convection effect). Consequently, the heat dissipation effect of the heat dissipation unit 4 is improved. Figure 7 In the modified example shown in (b), the shape of each heat dissipation fin 41 is L-shaped from a side view. Furthermore, the two L-shaped heat dissipation fins 41 are arranged in an up-down, opposite-facing configuration. This further increases the surface area (heat dissipation area) of the heat dissipation fins 41. As a result, the heat dissipation effect of the heat dissipation section 4 is improved. Figure 7 In the variation shown in (c), each heat dissipation fin 41, viewed from the side, is a short, stepped strip extending diagonally downwards and to the right in the drawing. In other words, each heat dissipation fin 41 extends obliquely and intersectingly relative to the vertical direction of the main body 2, with multiple steps. This increases the surface area of ​​the heat dissipation fins 41 while improving convection, thereby further enhancing the heat dissipation effect of the heat dissipation unit 4. Thus, with these configuration structures, the heat dissipation function achieved through the air surrounding the heat dissipation fins 41 can be improved.

[0068] (Connecting part) Figure 8 This is an enlarged view of the side portion of the photoreaction device according to the first embodiment of the present invention. (a) shows the state where the connecting part is retracted, and (b) shows the state where the connecting part protrudes. Figure 8 As shown, the connecting part 5 functions to connect the main body 2 to other devices. The connecting part 5 is slidably disposed between the heat dissipation fins 41. The connecting part 5 is rod-shaped so that it can be housed within the space 7 between the heat dissipation fins 41. The shape of the connecting part 5 is not limited to this and can be appropriately changed according to the shape of the heat dissipation fins 41, etc.

[0069] Thus, the connecting part 5 is configured to be able to be housed between the heat dissipation fins 41. Figure 8 The state shown in (a) is transformed into a state that protrudes upwards from the main body 2. Figure 8 (as shown in state (b)). The variable-position connecting part 5 enables miniaturization of the photoreactor 1. Furthermore, the main body 2 of the photoreactor 1 can be connected to other devices via the connecting part 5. For example, the upper end of the connecting part 5 can be connected and fixed to other devices. Such other devices include, for example, the main body 2 of another photoreactor 1, a stirring device, a support for fixing the reaction vessel 10, etc. To achieve this fixing, the connecting part 5 includes fastening (fixing) components such as screws and nuts. The fixing method of the connecting part 5 is not particularly limited; for example, fixing by fastening, fitting, bonding, welding, etc., can be listed.

[0070] When other devices are other photoreaction devices 1, the photoreaction device 1 can be configured as upper and lower sections. This makes it easy to increase the light irradiation area of ​​the light source section 3. The number of connecting parts 5 is not particularly limited, but preferably two or more, more preferably two or more and eight or less. In this case, it is particularly preferable that each connecting part 5 is evenly distributed along the outer peripheral surface of the main body section 2 in the space 7. This ensures the connection strength between the main body section 2 and other devices. Furthermore, the structure of the connecting parts 5 is not limited to the above structure. For example, the connecting parts 5 can also be configured as follows: Figure 3 As shown in (c), the four main body parts 2 are connected to each other. In this case, it is sufficient to provide a connecting part 5 on the upper surface 22 or the bottom surface 23 of the main body part 2.

[0071] (Configuration Support Department) The configuration aid 6 assists in the configuration of various components on the main body 2. The configuration aid 6 is located at the upper end of the main body 2 and at the upper end of the heat dissipation fins 41. The configuration aid 6 is annular in shape. The width of the annular portion of the configuration aid 6 is approximately the same as the thickness of the main body 2 and the length of the heat dissipation fins 41 protruding from the main body 2. Therefore, the configuration aid 6 can be stably mounted on the heat dissipation fins 41 and also protects the heat dissipation fins 41 from external damage.

[0072] The configuration aid 6 has multiple holes 61 and multiple recesses 62. The multiple holes 61 are through holes penetrating the configuration aid 6. The multiple holes 61 are arranged along the circumference of the annular configuration aid 6 on its upper surface. Furthermore, multiple LED arrays 31 are arranged inside the main body 2, aligned with the positions of the multiple holes 61. In addition, multiple heat dissipation fins 41 are arranged outside the main body 2 such that the holes 61 are located between the heat dissipation fins 41. Through the holes 61, an abutment structure between the LED arrays 31 and the heat dissipation fins 41 can be reliably formed. Thus, the holes 61 function to indicate the positions of the LED arrays 31 and the heat dissipation fins 41 in the main body 2.

[0073] Furthermore, the recess 62 serves to guide the connecting portion 5 when it protrudes upwards. The recess 62 is formed to be recessed from the outer periphery of the annular arrangement auxiliary portion 6 toward its inner periphery. The size of the recess 62 is not particularly limited, as long as the connecting portion 5 can pass through and does not intersect with the hole 61. The number of recesses 62 is not particularly limited, but preferably corresponds to the number of connecting portions 5. Thus, the connecting portion 5 can be moved while maintaining the strength of the arrangement auxiliary portion 6. When the main body 2 is connected to other devices, the arrangement auxiliary portion 6 can also function as a mounting component for that device. The configuration of the arrangement auxiliary portion 6 is not limited to the above configuration. For example, as... Figure 1 As shown, the configuration auxiliary part 6 can also be provided at the upper or lower end of the main body part 2, or it can be omitted.

[0074] <<Second Implementation>> Next, a second embodiment of the photoreaction device of the present invention will be described based on the accompanying drawings.

[0075] Figure 9 This is a perspective view schematically illustrating the photoreaction device according to the second embodiment of the present invention. The second embodiment will be described below, focusing on the differences from the first embodiment described above; identical details will be omitted. It should be noted that the same reference numerals are used for configurations identical to those in the first embodiment described above.

[0076] The photoreaction device 1 of this embodiment differs from the photoreaction device 1 of the first embodiment in that it has a two-section structure consisting of feet 8 and a main body 2. Specifically, the photoreaction device 1 of this embodiment has a first photoreaction device 1 and a second photoreaction device 1 disposed on the first photoreaction device 1. The first photoreaction device 1 has multiple feet 8 at the lower end of the main body 2. As a result, the mounting surface of the photoreaction device 1 can be separated from the bottom surface 23 of the main body 2. Therefore, air can flow from the inside of the main body 2 to the lower side. Consequently, the heat generated by the light source 3 can also diffuse from the lower side of the main body 2. Therefore, the temperature controllability of the photoreaction device 1 can be improved.

[0077] Furthermore, a second photoreaction device 1 is provided as another device on the upper side of the main body 2. These main body parts 2 are connected and fixed to each other by connecting parts 5. Specifically, the connecting part 5 of the first photoreaction device 1 is moved from the space 7 of the first photoreaction device 1 through the recess 62 of the placement auxiliary part 6 to the space 7 of the second photoreaction device 1 by half the length of the connecting part 5. Then, the fastening member below the connecting part 5 is fixed to the main body 2 of the first photoreaction device 1, and the fastening member above the connecting part 5 is fixed to the main body 2 of the second photoreaction device 1. Thus, the first photoreaction device 1 and the second photoreaction device 1 can be connected and fixed. With this configuration, the irradiation area of ​​the light source part 3 can be increased to about 2 times. Therefore, the light irradiation area of ​​the photoreaction device 1 can be easily changed according to the size or number of reaction containers 10. As a result, the reproducibility of the photoreaction can be easily improved. The photoreaction device 1 of this embodiment also has the same effect as the photoreaction device 1 of the first embodiment.

[0078] This invention is not limited to the two-segment structure described above; a multi-segment structure can also be used. In this case, the connecting portion 5 of the second (middle) photoreactive device 1 is located in a space 7 different from the space 7 where the connecting portion 5 of the first (lower) photoreactive device 1 is fixed. Correspondingly, the recess 62 of the placement auxiliary portion 6 of the second photoreactive device 1 is formed at a different position than the recess 62 of the placement auxiliary portion 6 of the first photoreactive device 1. Therefore, the connecting portion 5 of the lower photoreactive device 1 will not interfere with the connecting portion 5 of the middle photoreactive device 1.

[0079] <<Third Implementation>> Next, a third embodiment of the photoreaction device of the present invention will be described based on the accompanying drawings.

[0080] Figure 10This is a schematic top view illustrating the photoreaction device according to the third embodiment of the present invention. The third embodiment will be described below, focusing on the differences from the first embodiment described above; identical details will be omitted. It should be noted that the same reference numerals are used for configurations identical to those in the first embodiment described above.

[0081] The photoreaction apparatus 1 of this embodiment differs from the photoreaction apparatus 1 of the first embodiment in terms of the configuration of the partition 9 and the light source 3. Specifically, the partition 9 is a plate-shaped member disposed inside the main body 2 in such a way that it divides the light source 3 into two regions. Correspondingly, the light source 3 has a first light source region 3A and a second light source region 3B. The first light source region 3A and the second light source region 3B are configured to emit light at different wavelengths. That is, the LED array 31 in the first light source region 3A is configured to emit light at a first wavelength, and the LED array 31 in the second light source region 3B is configured to emit light at a second wavelength. For example, the LED array 31 in the first light source region 3A can emit light at a first wavelength in the ultraviolet region (e.g., 300 nm), and the LED array 31 in the second light source region 3B can emit light at a second wavelength in the visible light region (e.g., 500 nm). Thus, a single photoreaction apparatus 1 can be used to promote photoreactions in two reaction containers 10 respectively. Therefore, it is possible to complete the photoreaction of raw materials with different reaction efficiencies due to different wavelengths in one device at a time. It should be noted that the separator 9 can also be omitted, and a reaction vessel 10 can be irradiated with the first wavelength and the second wavelength respectively.

[0082] The light source unit 3 is not limited to the two light source regions 3A and 3B mentioned above, and may also have multiple light source regions corresponding to wavelength regions. These multiple light source regions may include, for example, visible light regions, ultraviolet light regions, near-infrared light regions, etc., which have wavelengths representing different colors. In this case, photoreaction of various raw materials with different photoreaction efficiencies can be carried out efficiently in a single photoreaction device 1.

[0083] Thus, the light source unit 3 is configured to independently control the light illumination of the LED array 31 in the first light source region 3A and the light illumination of the LED array 31 in the second light source region 3B. This control can be achieved by providing a first switch connected to a plurality of LEDs 311 of the LED array 31 in the first light source region 3A, and a second switch connected to a plurality of LEDs 311 of the LED array 31 in the second light source region 3B, and switching them on and off manually or via a relay. Alternatively, the light source unit 3 can also be controlled by the light source control unit described in the first embodiment. This light reaction device 1 also has the same effect as the light reaction device 1 of the first embodiment.

[0084] The photoreaction apparatus of the present invention has been described above based on preferred embodiments, but the present invention is not limited to these embodiments. The structure of each component can be modified or replaced with any structure having the same function. Furthermore, in the present invention, any two or more structures (features) in each embodiment can be combined. Further, other arbitrary devices or components can be added to the present invention. For example, the photoreaction apparatus of the present invention may include a blower. Furthermore, the photoreaction apparatus of the present invention can also be configured as a photoreaction apparatus (photoreaction apparatus kit) together with a reaction vessel, a stirrer for the reaction vessel, a support, a blower, and / or other chemical experimental apparatus. Preferably, a photoreaction apparatus kit includes at least a blower. According to the evaluation results of temperature control described later, the effect of the heat dissipation fins can be further improved by the blower. Therefore, with such a photoreaction apparatus kit, the temperature control of the photoreaction apparatus can be particularly improved.

[0085] The present invention will now be described in detail based on embodiments, but the present invention is not limited thereto.

[0086] Light reaction experiment (1) (Example 1A) Under an argon atmosphere, 0.2 mmol of 2,6-diethylaniline and 5.0 mL of acetonitrile were added to a 20 mL pear-shaped double-necked flask (reaction vessel) equipped with a magnetic stirrer to dissolve the starting material. Next, 1.0 mL of water-soluble Eosin Y (10 mol%), ascorbic acid (4.0 eq.), cesium carbonate (Cs₂CO₃, 1 eq.), and tridecafluoro-1-iodohexane (4.5 eq.) were added to the reaction vessel. The reaction vessel was then placed in the center of a 30 W photoreactor 1 and irradiated with green light for 1 hour while stirring at room temperature. The irradiated solution was extracted with dichloromethane to obtain the organic phase. The obtained organic phase was washed with saturated brine, dried on anhydrous sodium sulfate, filtered, and concentrated to obtain the crude product. The crude product was purified by silica gel column chromatography (developing solvent: n-hexane: ethyl acetate = 70:1) to obtain a C6F group introduced at the 4-position of 2,6-diethylaniline. 13 The target product. Its yield was 87%.

[0087] (Example 2A) Except that the reaction vessel was positioned at the end of the photoreaction device 1, i.e., close to the inner circumferential surface of the photoreaction device 1, the photoreaction experiment (1) was performed using the same steps as in Example 1A. The yield of the target product was 84%.

[0088] (Example 3A) Except for the green light irradiation time of 10 minutes, the photoreaction experiment (1) was performed using the same procedure as in Example 1A. The yield of the target product was 5%.

[0089] (Comparative Example 1A) Except for using a point-source LED lamp (manufactured by CCS, model: HLV-22SW-2, power consumption: 2.5W) instead of photoreaction device 1, the photoreaction experiment (1) was performed using the same steps as in Example 1A. The yield of the target product was 0.8%. It should be noted that the point-source LED lamp was positioned on the front side of the reaction vessel.

[0090] The main conditions and results (yield) of the above photoreaction experiment (1) are shown in Table 1 below.

[0091] [Table 1]

[0092] As shown in Table 1, a high yield can be maintained when using photoreaction apparatus 1. It should be noted that when the photoreaction experiment (1) was performed three times using the same steps as in Example 1A, the yield difference was within 1%. From these results, it can be seen that, according to the present invention, a photoreaction apparatus with excellent reproducibility of photoreaction can be provided.

[0093] <Light Reaction Experiment (2)> (Example 1B) Under an argon atmosphere, 0.2 mmol of 2,6-diethylaniline and 5.0 mL of acetonitrile were added to a 20 mL pear-shaped double-necked flask (reaction vessel) equipped with a magnetic stirrer to dissolve the starting material. Next, 1.0 mL of water-soluble Eosin Y (10 mol%), ascorbic acid (4.0 eq.), cesium carbonate (Cs₂CO₃, 1.0 eq.), and 6.0 eq. of 1,4-diiodoperfluorobutane were added to the reaction vessel. The reaction vessel was placed in the center of a 30 W photoreactor 1 and irradiated with blue light for 1 hour while stirring at room temperature. The irradiated solution was extracted with dichloromethane to obtain the organic phase. The obtained organic phase was washed with saturated brine, dried on anhydrous sodium sulfate, filtered, and concentrated to obtain the crude product. The crude product was purified by silica gel column chromatography (developing solvent: n-hexane: ethyl acetate = 70:1) to obtain the target product with C4F8I introduced at the 4 position of 2,6-diethylaniline. The yield was 80%.

[0094] (Example 2B) Except that the irradiation light of photoreaction device 1 was changed to white light, the photoreaction experiment (2) was performed using the same steps as in Example 1B. The yield of the target product was 76%.

[0095] (Example 3B) Except that the irradiation light of photoreaction device 1 was changed to green light, the photoreaction experiment (2) was performed using the same steps as in Example 1B. The yield of the target product was 72%.

[0096] (Example 4B) Except for changing the power consumption of photoreactor 1 to 15W, the photoreactor experiment (2) was performed using the same steps as in Example 1B. The yield of the target product was 63%.

[0097] (Example 5B) Except for changing the irradiation light of photoreaction device 1 to white light and changing the power consumption of photoreaction device 1 to 15W, the photoreaction experiment (2) was performed using the same steps as in Example 1B. The yield of the target product was 60%.

[0098] (Comparative Example 1B) Except for using a point-source LED lamp (manufactured by CCS, model: HLV-22SW-2, power consumption: 2.5W) instead of photoreaction device 1, the photoreaction experiment (2) was performed using the same steps as in Example 1B. The yield of the target product was 5%. It should be noted that the point-source LED lamp was positioned on the front side of the reaction vessel.

[0099] (Comparative Example 2B) Except that the illumination light from the point source LED lamp was changed to white light, the photoreaction experiment (2) was performed using the same procedure as Comparative Example 1B. The yield of the target product was 8%.

[0100] (Comparative Example 3B) Except that the illumination light from the point source LED lamp was changed to green light, the photoreaction experiment (2) was performed using the same procedure as Comparative Example 1B. The yield of the target product was less than 1% (trace).

[0101] (Comparative Example 4B) Except that a point-source LED lamp (Linji Keiko Industrial Co., Ltd. Spot Ace SPA-10CW, power consumption 12W) was used instead of photoreaction device 1, the photoreaction experiment (2) was performed using the same procedure as in Example 1B. The yield of the target product was 28%. It should be noted that the point-source LED lamp was positioned on the front side of the reaction vessel.

[0102] The main conditions and results (yield) of the above photoreaction experiment (2) are shown in Table 2 below.

[0103] [Table 2]

[0104] As shown in Table 2, a high yield can be maintained when using photoreaction device 1. In particular, when comparing Example 1B with Example 4B, it was found that a high yield can still be maintained even when the power consumption is halved. From these results, it can be seen that, according to the present invention, a photoreaction device that achieves efficient light irradiation and excellent reproducibility of the photoreaction can be provided.

[0105] <Experiments on temperature control> (Example 1C) To evaluate the temperature controllability of the photoreactor, the temperature suppression rate was determined by measuring the water temperature change with and without heat dissipation fins. First, 15 mL of water was added to the reaction vessel (30 mL flask). Figure 2 As shown in the example, the reaction vessel is placed inside the photoreactor and its upper part is clamped by a support. Furthermore, a silicone membrane component (septum) is used to cover the inlet of the reaction vessel. To measure the water temperature in the reaction vessel, the measuring part of a digital thermometer is inserted through the membrane component into the water in the reaction vessel. The water temperature was then measured before the photoreactor was irradiated. Next, the water temperature was measured immediately after 2 hours of irradiation.

[0106] (Example 2C) Except for using a desktop blower to deliver air to the photoreaction device at a wind speed of about 1 m / s, the water temperature was measured using the same procedure as in Example 1C.

[0107] (Comparative Example 1C) The heat dissipation section of the photoreactor was covered with masking tape. This eliminated the function of the heat dissipation fins in the photoreactor. Thus, except for preparing a photoreactor without heat dissipation fins, the water temperature change was measured in the same manner as in Example 1C.

[0108] (Comparative Example 2) Except for using a desktop blower to deliver air to the photoreactor at a wind speed of about 1 m / s, the water temperature was measured using the same procedure as in Comparative Example 1C.

[0109] <Water Temperature Measurement Results> The water temperature before and after light irradiation, and the temperature rise before and after light irradiation for each embodiment and comparative example are shown in Table 3 below.

[0110] [Table 3]

[0111] Using the results in Table 3, the comparison results 1 between Example 1C and Comparative Example 1C, and the comparison results 2 between Example 2C and Comparative Example 2C are shown in Table 4 below.

[0112] [Table 4]

[0113] <Evaluation results of temperature control> As shown in Table 4 above, the presence of heat dissipation fins can suppress the temperature rise by 19%. Furthermore, the simultaneous use of a blower can suppress the temperature rise by 39%. It should be noted that these results are related to water temperature changes. Specifically, the specific heat capacity of water is approximately 4.18 J / g·K. The specific heat capacity of most organic solvents used in photoreactions is about half that of water. For example, the specific heat capacity of acetone and acetonitrile is approximately 2.2 J / g·K, about 52% of that of water. Therefore, when using organic solvents instead of water in the same examples and comparative examples, the temperature rise of the solvent before and after light irradiation will be approximately twice the original. For example, the temperature rise in Comparative Example 1C is approximately 40°C. Such a high temperature rise may not only reduce the lifespan of the photoreaction device but also adversely affect the reaction yield. For example, unexpected products may be obtained due to thermal reactions. From this perspective, the temperature controllability of the photoreaction device is also an important characteristic related to the reproducibility of the photoreaction. Therefore, according to the present invention, the temperature controllability of the photoreaction device can be easily improved, thereby easily achieving both the reproducibility of the photoreaction and the temperature controllability.

Claims

1. A photoreaction device for promoting a photoreaction within a reaction vessel, characterized in that, include: Main body; The light source unit is disposed on one side of the main body unit; A heat dissipation section is provided on the opposite side of the main body.

2. The photoreaction device according to claim 1, characterized in that, The light source unit includes multiple LED arrays.

3. The photoreaction device according to claim 2, characterized in that, The plurality of LED arrays are arranged in a direction orthogonal to the vertical direction of the main body.

4. The photoreaction device according to claim 3, characterized in that, The plurality of LED arrays include a first LED array and a second LED array adjacent to the first LED array; The first LED array and the second LED array are offset from each other in the vertical direction of the main body.

5. The photoreaction device according to claim 1, characterized in that, The light source section includes at least a first light source region that emits light at a first wavelength and a second light source region that emits light at a second wavelength.

6. The photoreaction device according to claim 1, characterized in that, The heat dissipation section includes multiple heat dissipation fins.

7. The photoreaction device according to claim 6, characterized in that, The plurality of heat dissipation fins are arranged in a direction orthogonal to the vertical direction of the main body.

8. The photoreaction device according to claim 7, characterized in that, The plurality of heat dissipation fins are respectively formed into elongated strips along the vertical direction.

9. The photoreaction device according to claim 8, characterized in that, The light source includes an LED array arranged parallel to the vertical direction; Multiple heat dissipation fins are arranged parallel to the LED array.

10. The photoreaction device according to claim 9, characterized in that, The LED array is disposed between the plurality of heat dissipation fins and on one side of the main body.

11. The photoreaction device according to claim 6, characterized in that, It also includes a connecting part for connecting the main body and other devices different from the photoreaction device; The connecting portion is disposed between the plurality of heat dissipation fins.

12. The photoreaction device according to claim 1, characterized in that, It also includes a foot portion disposed on the bottom surface of the main body portion.

13. The photoreaction device according to claim 1, characterized in that, The main body has a cylindrical structure.

14. A photoreaction device kit, characterized in that, include: The photoreaction device according to any one of claims 1 to 13; The reaction vessel is disposed adjacent to the light source section of the photoreaction device.

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