Insecticidal compositions containing dimpropyridaz and their use

Abstract

The application belongs to the technical field of pesticide insecticide, and discloses a kind of insecticidal composition containing dimpropyridaz and application thereof, active ingredient of the insecticidal composition includes active ingredient A and active ingredient B, active ingredient A is dimpropyridaz, active ingredient B is any one of pyridyl quinazoline or chlorfenapyr, and the mass ratio of active ingredient A to active ingredient B is 1:48~50:1.The insecticidal composition has excellent control effect on a plurality of pests in Lepidoptera, Hemiptera and Thysanoptera, effectively controls the harm of pests to crops, reduces the use dose of field pesticide, and reduces the cost of agricultural production.

Description

Technical Field

[0001] This invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition containing dimpropyridaz and its application. Background Technology

[0002] dimpropyridaz, CAS Registry Number: 1403615-77-9, is a novel insecticidal / acaricidal active compound belonging to the pyridazine class. It acts on specific target sites of insects, exhibiting both contact and stomach poison effects. It is highly effective against piercing-sucking and chewing pests as well as mites, with a broad insecticidal spectrum, high activity, long residual effect, and good environmental compatibility. It is widely used for pest control in crops.

[0003] Chlorfenapyr, CAS Registry Number: 122453-73-0, is an arylpyrrole insecticide and acaricide. It belongs to the oxidative phosphorylation uncoupling agent class and acts on insect mitochondria, disrupting the proton gradient of the inner mitochondrial membrane, blocking ATP synthesis, and preventing cellular energy supply. Insects poisoned by this agent become lethargic, paralyzed, and die. It possesses contact, stomach, and some systemic activity, exhibiting a broad spectrum of insecticidal and acaricidal activity. It is particularly effective against lepidopteran and hemiptera pests and various mites, with good rapid action and a moderate residual effect, and is widely used in fruits, vegetables, and field crops.

[0004] Pyrifluquinazon, CAS Registry Number: 337458-27-2, is a novel quinazoline insecticide belonging to the IRAC 9B class. It acts on the TRPV channels of insects, acting as a feeding blocker, causing starvation and death in piercing-sucking pests. It is highly effective against aphids, whiteflies, and thrips.

[0005] The scientific formulation of pesticides is a common method for controlling agricultural pests and diseases. Combining the mechanisms of action of different pesticides in a formulation broadens the control spectrum, achieving multiple treatments with a single pesticide, reducing the number of applications and labor costs. It can significantly improve efficacy, accelerate the onset of action, delay the development of pesticide resistance in pests and diseases, and extend the lifespan of single pesticides. Some combinations can also exert synergistic effects, reducing the dosage of single pesticides, decreasing pesticide residues and environmental pollution, and improving pesticide safety. Furthermore, formulated pesticides are suitable for different crops and field pest infestations, offering greater applicability and avoiding the limitations of single pesticides, thus ensuring stable crop yields and improved quality. Summary of the Invention

[0006] Based on the above, this invention rationally combines dimpropyridaz with any one of chlorfenapyr or pyridinequinazoline, and screens out suitable compound ratios for different target pests. The synergistic effect is significant, which greatly improves the control effect, reduces the amount of pesticide used, reduces agricultural production costs, and effectively delays the development of pest resistance to single pesticides.

[0007] To achieve the above objectives, the present invention adopts the following technical solution: an insecticidal composition containing dimpropyridaz, wherein the active ingredients of the insecticidal composition include active ingredient A and active ingredient B, wherein active ingredient A is dimpropyridaz, and active ingredient B is either chlorfenapyr or pyridinium quinazoline, and the mass ratio of active ingredient A to active ingredient B is 1:48 to 50:1, or any value within the above range.

[0008] Furthermore, the mass ratio of dimpropyridaz to chlorfenapyr is 1:32 to 50:1, or any value within the above range. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:45 to 36:1, or any value within the above range.

[0009] Furthermore, the mass ratio of dimpropyridaz to chlorfenapyr is 1:32 to 30:1, or any value within the above range. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:30 to 32:1, or any value within the above range; Furthermore, the mass ratio of dimpropyridaz to chlorfenapyr is 1:20 to 30:1, or any value within the above range; The mass ratio of dimpropyridaz to pyridinequinazoline is 1:35 to 24:1, or any value within the above range.

[0010] Further, the mass ratio of dimpropyridaz to chlorfenapyr is 1:32, 1:24, 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, 30:1, 40:1, or 50:1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:45, 1:35, 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, 24:1, 32:1, and 36:1. Furthermore, the mass ratio of dimpropyridaz to chlorfenapyr is 1:32, 1:24, 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, or 30:1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, 24:1, or 32:1. More preferably, the mass ratio of dimpropyridaz to chlorfenapyr is 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, or 30:1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:35, 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, and 24:1.

[0011] Furthermore, the total weight of the insecticidal composition is 100 wt%, and the combined weight of active ingredient A and active ingredient B accounts for 0.5% to 80% of the total weight of the insecticidal composition.

[0012] Furthermore, the insecticidal composition, in addition to the active ingredient, also contains pesticide-acceptable auxiliary ingredients, which are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, or carriers.

[0013] Furthermore, the insecticidal composition is prepared as a solid or liquid formulation.

[0014] Furthermore, the solid formulation is a water-dispersible granule or a wettable powder; the liquid formulation is a suspension concentrate, emulsifiable concentrate, water emulsion, microemulsion, or dispersible oil suspension.

[0015] The present invention also discloses the use of the insecticidal composition described above for the control of crop pests.

[0016] Furthermore, the pests mentioned are lepidopteran pests, hemiptera pests, or thalassoptera pests. Furthermore, the Lepidoptera pests are beet armyworm, diamondback moth, cabbage caterpillar, and rice stem borer; the Hemiptera pests are rice planthopper, aphid, and whitefly; and the Thysanoptera pests are thrips.

[0017] The beneficial effects of this invention are as follows: The insecticidal composition of the present invention expands the insecticidal spectrum by rationally combining compounds with different mechanisms of action, and has a significant synergistic effect on different types of target pests. The insecticidal composition of the present invention requires a low dosage, reduces agricultural production costs, and has the comprehensive advantages of scientific pesticide use. Detailed Implementation

[0018] To make the technical solutions, objectives and advantages of the present invention clearer, the present invention is illustrated by the following specific formulation preparation examples and experimental examples. However, the present invention can be implemented in various forms and should not be limited to the formulation preparation examples and implementation methods described herein.

[0019] Examples of preparation of some formulations of the insecticidal composition of the present invention and corresponding preparation methods are as follows: 1. Preparation method of water-dispersible granules: According to the formula ratio, add the active ingredients to the carrier, and add surfactants and other functional additives to it. Mix, and after air jet milling, add 10-25% water. Then knead, granulate, dry and sieve to obtain water-dispersible granules; or spray water, granulate and dry the pulverized powder in a fluidized bed granulator, and then sieve to obtain the product.

[0020] 2. Preparation method of wettable powder: According to the formula ratio, the active ingredients, dispersant, wetting agent and filler are mixed and stirred evenly in a mixer. After being pulverized by an air jet mill, they are mixed evenly again to prepare the wettable powder of the composition of the present invention.

[0021] 3. Preparation method of emulsifiable concentrate: According to the formula ratio, add the measured active ingredients, solvent and co-solvent into the mixing tank and stir to dissolve them. Then add the emulsifier, and use the remaining solvent to make up the balance. Stir evenly in the mixing tank, and filter to obtain the emulsifiable concentrate required by the present invention.

[0022] 4. Preparation method of suspension: According to the formula ratio, place the active ingredients, surfactants and other functional additives in the reaction vessel in sequence, add water and mix evenly, then perform high-speed shearing, wet sand milling, and finally homogenization filtration to obtain the suspension product.

[0023] 5. Microemulsion preparation method: According to the formula ratio, the active ingredients, solvents, emulsifiers, etc. are mixed evenly to obtain the oil phase. The antifreeze and water are mixed evenly to obtain the aqueous phase. The oil phase is added to the aqueous phase under stirring and stirred evenly. Shearing is continued for 10 minutes. Then, the defoamer is added and stirred evenly to obtain small droplets with oil phase particles of 0.01~0.1 micrometers, which is the microemulsion product.

[0024] Preparation Example 1: 26% dimpropyridaz·chlorfenapyr suspension (1:12) Formula composition: 2% dimpropyridaz, 24% chlorfenapyr, 1% sodium alkyl polyoxyethylene ether sulfonate, 1% sodium polycarboxylate, 3% arylphenol polyoxyethylene ether phosphate, 0.25% xanthan gum, 1% magnesium aluminum silicate, 4% ethylene glycol, 0.01% potassium benzisothiazolinone, 0.5% silicone oil, deionized water to make up the balance.

[0025] Preparation Example 2: 8% dimpropyridaz·chlorfenapyr emulsifiable concentrate (1:1) Formula composition: 4% dimpropyridaz, 4% chlorfenapyr, 12% DMF, 12% tristyrene-phenylphenol polyoxyethylene ether polyoxypropylene ether, 2% calcium dodecylbenzenesulfonate, 18% propylene carbonate, xylene to make up the balance.

[0026] Preparation Example 3: 24% dimpropyridaz·chlorfenapyr wettable powder (1:3) Formula composition: 6% dimpropyridaz, 18% chlorfenapyr, 5% sodium dodecyl sulfate, 3% naphthalene sulfonate formaldehyde condensate, 2.5% bleaching powder BX, 7% silica, and kaolin to make up the balance.

[0027] Preparation Example 4: 21% dimpropyridaz·chlorfenapyr water-dispersible granules (20:1) Formula composition: 20% dimpropyridaz, 1% chlorfenapyr, 6% styrene-phenol polyoxyethylene ether sulfate, 2% naphthalene sulfonate, 2% sodium dodecyl sulfate, 8% ammonium sulfate, starch to make up the balance.

[0028] Preparation Example 5: 11% dimpropyridaz·chlorfenapyr microemulsion (1:10) Formula composition: 1% dimpropyridaz, 10% chlorfenapyr, 15% xylene, 20% cyclohexanone, 12% gerbert alcohol polyoxyethylene ether, 3% EO-PO block copolymer, 1% sodium alkyl polyoxyethylene ether sulfonate, 5% ethylene glycol, 0.05% silicone defoamer, deionized water to make up the balance.

[0029] Preparation Example 6: 28% dimpropyridaz·pyridinequinazoline suspension (3:1) Formula composition: 21% dimpropyridazine, 7% pyridinequinazoline, 1% ethylene glycol oxyethylene polyoxypropylene ether, 4% arylphenol oxyethylene ether phosphate, 1% sodium lignosulfonate, 0.25% xanthan gum, 5% ethylene glycol, 0.1% sodium benzoate, 0.5% silicone oil, deionized water to make up the balance.

[0030] Preparation Example 7: 16% dimpropyridaz·pyridinequinazoline emulsifiable concentrate (1:15) Formula composition: 1% dimpropyridazine, 15% pyridinequinazoline, 20% N-methylpyrrolidone, 10% sorbitan oleate polyoxyethylene ether, 2% naphthalene sulfonate formaldehyde condensate, 10% DMF, methyl oleate to make up the balance.

[0031] Preparation Example 8: 20% dimpropyridaz·pyridinequinazoline wettable powder (1:1) Formula composition: 10% dimpropyridazine, 10% pyridinequinazoline, 2% sodium alkyl polyoxyethylene ether sulfonate, 3% alkyl naphthalene sulfonate, 6% sodium octylphenol polyoxyethylene ether sulfonate, 10% kaolin, 8% silica, and bentonite to make up the balance.

[0032] Preparation Example 9: 30% dimpropyridaz·pyridinequinazoline water-dispersible granules (9:1) Formula composition: 27% dimpropyridazine, 3% pyridinequinazoline, 10% sodium lignosulfonate, 2% BX (a type of lignosulfonate), 2% naphthalenesulfonate formaldehyde condensate, 6% white sugar, and kaolin to make up the balance.

[0033] Preparation Example 10: 13% dimpropyridaz·pyridinequinazoline microemulsion (12:1) Formula composition: 12% dimpropyridazine, 1% pyridinequinazoline, 20% cyclohexanone, 10% glycerol fatty acid ester polyoxyethylene ether, 3% alkylphenol polyoxyethylene ether, 1% sodium alkyl polyoxyethylene ether sulfonate, 0.05% silicone defoamer, deionized water to make up the balance.

[0034] Example 1: Indoor bioactivity test.

[0035] Experimental targets: 3rd instar larvae of beet armyworm, adult western flower thrips, nymphs of rice planthopper, and adult whitefly.

[0036] Test agents: dimpropyridaz, chlorfenapyr, and pyridinequinazoline technical grade.

[0037] Reagent preparation: Dissolve the test drug in a suitable solvent, and then dilute it with a 0.1% Tween 80 aqueous solution. Based on the drug activity, set up 5 series of mass concentrations using a proportional method.

[0038] Different experimental methods are set according to different experimental targets as follows: 1. Indoor biological activity test for controlling beet armyworm: The experiment followed NY / T 1154.6-2006 "Guidelines for Indoor Biological Testing of Pesticides - Insecticides Part 6: Insecticidal Activity Test - Immersion Method". Beet armyworms were immersed in the pesticide solution for 5 seconds, and excess solution was absorbed with filter paper. The insects were then transferred to normal rearing conditions. Each treatment was repeated four times, with 20 insects per replicate. A treatment without the pesticide and the corresponding organic solvent was included as a control. The mortality rate of the insects was assessed 48 hours after treatment, and the number of dead insects was recorded.

[0039] 2. Indoor Bioactivity Test for Thrips Control: The experiment used the leaf tube film method. 4 mL centrifuge tubes were filled with the test pesticide, shaken several times, and the solution was discarded. The tubes were then opened and placed on a rack on the experimental table to dry. Several small holes were pricked in the bottom and cap of the centrifuge tubes with a needle tip, the hole size being designed to prevent thrips from escaping. Fresh, untreated cowpea pods were cut into 1.5 cm segments, immersed in the test pesticide solution for 10 seconds, removed, and allowed to air dry on absorbent paper before being placed in the centrifuge tubes. Twenty adult thrips were then sucked in using a suction device, and the tubes were capped. Each tube represented one replicate, and each treatment was replicated four times. The centrifuge tubes were incubated in an intelligent artificial climate chamber at (26±1)℃ with a photoperiod of 14L:10D. After 48 hours, the mortality rate was checked by gently touching the insects with the tip of a paintbrush; those that did not move were considered dead.

[0040] 3. Indoor bioactivity test for controlling rice planthoppers: NY / T 1154.11-2008 "Guidelines for Indoor Bioassay of Pesticides - Insecticides Part 11: Rice Stem Immersion Method". Healthy, uniformly growing rice seedlings at the tillering stage were selected, dug up with roots, washed, and cut into 10cm long rooted rice stems, which were then dried in a cool, shaded place. The rice seedlings were immersed in the pesticide solution for 30 seconds, then removed and dried. The roots of the seedlings were wrapped with absorbent cotton, covered with plastic wrap, and the bottom was submerged in water before being placed in disposable plastic cups. Each cup was inoculated with 30 standard, uniform mid-third instar nymphs, and sealed with fine gauze. Each treatment was repeated four times, with a 0.1% Tween-80 aqueous solution used as a blank control. After inoculation, the seedlings were placed in an intelligent artificial climate chamber with a temperature of (28±1)℃, a relative humidity of 75%±5%, and a photoperiod of 16L:8D for cultivation. Check the mortality status after 48 hours. Gently touch the insect body with a No. 0 brush. If it does not move at all, it is considered dead.

[0041] 4. Indoor Bioactivity Test for Controlling Whiteflies: The experiment was conducted according to NY / T 1154.14-2008 "Guidelines for Indoor Bioassay of Pesticides - Insecticides Part 14: Leaf Immersion Method". Fresh, untreated chili pepper leaves of similar size and color were selected. Suitable leaf discs were made using a perforator. The leaf discs were immersed in the test solution for 10 seconds and then placed in an insect rearing box lined with moisturizing filter paper. Whiteflies raised indoors were inoculated onto the treated leaf discs, with 20 whiteflies per replicate and 4 replicates per treatment. A treatment containing a compatible solvent but without pesticide was included as a blank control. The insect rearing boxes were placed in an incubator at a temperature of (26±1)℃ and a photoperiod of L:D=(16:8)h for rearing.

[0042] Calculation method: Calculate the mortality rate for each treatment based on the survey data. Use the following formula:

[0043] In the formula: P — Mortality rate, expressed as a percentage (%); K —This indicates the number of dead insects, expressed in heads; N — This indicates the total number of insects treated, in units of heads.

[0044]

[0045] In the formula: P 1 —Adjusted mortality rate, in percentages (%); P t —The mortality rate is expressed as a percentage (%). P 0 — Mortality rate in blank control group, expressed as a percentage (%).

[0046] If the control mortality rate is <5%, no correction is needed; if the control mortality rate is between 5% and 20%, correction should be performed according to the corrected mortality rate formula; if the control mortality rate is >20%, the trial needs to be repeated.

[0047] The toxicity regression equation, correlation coefficient, and LC were obtained using a statistical analysis system. 50 The value is used to evaluate the activity of the test reagent on the biological sample.

[0048] The co-toxicity coefficient (CTC value) of the mixture is calculated using the following formula:

[0049] In the formula: YOU —Measured toxicity index of the mixture; S LC of standard insecticides 50 The unit is milligrams per liter (mg / L); M LC of the mixture 50 The unit is milligrams per liter (mg / L).

[0050]

[0051] In the formula: TTI —Theoretical toxicity index of the mixture; THE A —A. Toxicity index of drug A; P A —The percentage content of drug A in the mixture, expressed as a percentage (%). THE B —Toxicity index of drug B; P B —Percentage content of agent B in the mixture, expressed as percentage (%).

[0052]

[0053] In the formula: CTC —Cotoxicity coefficient; YOU —Measured toxicity index of the mixture; TTI —Theoretical toxicity index of mixed preparations.

[0054] Co-toxicity coefficient of compound CTC ≥120 exhibits a synergistic effect; CTC≤80 It exhibits antagonistic effects; 80 < CTC <120 exhibits an additive effect.

[0055] The results of the indoor tests are shown in the table below:

[0056] The results of indoor bioactivity tests (Table 1) showed that the combination of dimpropyridaz and chlorfenapyr at appropriate mass ratios significantly enhanced the efficacy against beet armyworm. When the mass ratio of dimpropyridaz to chlorfenapyr was 1:32–30:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio was 1:24–15:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect; and when the mass ratio was 1:12–8:1, the co-toxicity coefficient was greater than 140, indicating a significant synergistic effect. Among them, the mass ratios of dimpropyridaz and chlorfenapyr were 1:32, 1:24, 1:12, 1:6, 1:3, 2:1, 8:1, 15:1, and 30:1, with a co-toxicity coefficient greater than 120, showing a synergistic effect; the mass ratios of 1:24, 1:12, 1:6, 1:3, 2:1, 8:1, and 15:1, with a co-toxicity coefficient greater than 130, showing a significant synergistic effect; and the mass ratios of 1:12, 1:6, 1:3, 2:1, and 8:1, with a co-toxicity coefficient greater than 140, showing a significant synergistic effect.

[0057]

[0058] The results of the indoor bioactivity test (Table 2) showed that the combination of dimpropyridaz and chlorfenapyr at an appropriate mass ratio significantly enhanced the efficacy against thrips. When the mass ratio of dimpropyridaz to chlorfenapyr was 1:30–50:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio was 1:20–40:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect; and when the mass ratio was 1:20–30:1, the co-toxicity coefficient was greater than 140, indicating a significant synergistic effect. Among them, the mass ratios of dimpropyridaz and chlorfenapyr are 1:30, 1:20, 1:10, 1:1, 5:1, 10:1, 20:1, 30:1, 40:1, and 50:1, with a co-toxicity coefficient greater than 120, showing a synergistic effect; the mass ratios of 1:20, 1:10, 1:1, 5:1, 10:1, 20:1, 30:1, and 40:1, with a co-toxicity coefficient greater than 130, showing a significant synergistic effect; and the mass ratios of 1:20, 1:10, 1:1, 5:1, 10:1, 20:1, and 30:1, with a co-toxicity coefficient greater than 140, showing a significant synergistic effect.

[0059]

[0060] The results of indoor bioactivity tests (Table 3) showed that the combination of dimpropyridaz and pyridinequinazoline at appropriate mass ratios significantly enhanced the efficacy against rice planthoppers. When the mass ratio of dimpropyridaz to pyridinequinazoline was 1:45–36:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio was 1:35–24:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect; and when the mass ratio was 1:25–24:1, the co-toxicity coefficient was greater than 140, indicating a significant synergistic effect. Among them, the mass ratios of dimpropyridazine and pyridinequinazoline were 1:45, 1:35, 1:25, 1:10, 1:6, 3:1, 9:1, 18:1, 24:1, and 36:1, with a co-toxicity coefficient greater than 120, indicating a synergistic effect; the mass ratios of 1:35, 1:25, 1:10, 1:6, 3:1, 9:1, 18:1, and 24:1, with a co-toxicity coefficient greater than 130, indicating a significant synergistic effect; and the mass ratios of 1:25, 1:10, 1:6, 3:1, 9:1, 18:1, and 24:1, with a co-toxicity coefficient greater than 140, indicating a significant synergistic effect.

[0061]

[0062] The results of indoor bioactivity tests (Table 4) showed that the combination of dimpropyridaz and pyridinequinazoline at appropriate mass ratios significantly enhanced the efficacy against rice planthoppers. When the mass ratio of dimpropyridaz to pyridinequinazoline was 1:30–32:1, the co-toxicity coefficient was greater than 120, indicating a synergistic effect; when the mass ratio was 1:30–24:1, the co-toxicity coefficient was greater than 130, indicating a significant synergistic effect; and when the mass ratio was 1:20–12:1, the co-toxicity coefficient was greater than 140, indicating a significant synergistic effect. Among them, the mass ratios of dimpropyridazine and pyridinequinazoline were 1:30, 1:20, 1:15, 1:10, 1:5, 1:1, 8:1, 12:1, 24:1, and 32:1, with a co-toxicity coefficient greater than 120, indicating a synergistic effect; the mass ratios of 1:30, 1:20, 1:15, 1:10, 1:5, 1:1, 8:1, 12:1, and 24:1, with a co-toxicity coefficient greater than 130, indicating a significant synergistic effect; and the mass ratios of 1:20, 1:15, 1:10, 1:5, 1:1, 8:1, and 12:1, with a co-toxicity coefficient greater than 140, indicating a significant synergistic effect.

[0063] Example 2: Field efficacy test for controlling beet armyworm and diamondback moth.

[0064] Experimental site: The experiment was conducted in Beisong Village, Jiuhu Town, Zouping City, Binzhou City, Shandong Province. The soil fertility of the experimental site was medium to high, and the soil was sandy loam. The terrain was flat, the fertilizer and water conditions were good, and the management measures were consistent. The surrounding crops were cabbage, and the cabbage grew uniformly in the field. The cultivation and management were in line with local agricultural production practices.

[0065] Control targets: diamondback moth and beet armyworm.

[0066] Experimental design: The plot area is 20m² 2 Repeat 4 times, using randomized block arrangements.

[0067] Experimental Methods: Pesticides were applied during the seedling stage of cabbage, at the early stage of pest infestation. A Gongnong-16 backpack electric sprayer was used to evenly spray both sides of the cabbage leaves. A blank control (CK) used an equal volume of water. The initial pest population was assessed before application, and the control effect was assessed on days 3 and 10 after application. A random 5-point sampling method was used, with 4 plants marked at each point. Twenty plants were selected from each plot for fixed-point pest counting, and the pest population reduction rate and control effect were calculated.

[0068] The method for calculating drug efficacy is as follows:

[0069]

[0070] The results of the field efficacy trials are shown in the table below:

[0071] Table 5 shows that the combination of dimpropyridaz and chlorfenapyr has a good control effect on cabbage looper and diamondback moth. Three days after application, the dimpropyridaz·chlorfenapyr compound formulation at 40 g / hm² is effective. 2 The control efficacy against lepidopteran pests of cabbage was 84.68%–90.81%. Ten days after application, the field control efficacy of 24% dimpropyridaz·chlorfenapyr wettable powder (1:3) against beet armyworm and diamondback moth was the highest at 94.30%, significantly higher than that of the single-agent control.

[0072] Example 3: Field efficacy test for controlling rice planthoppers.

[0073] Experimental location: The experiment was conducted in paddy fields in Changma Village, Tiandian Town, Yingcheng City, Xiaogan City, Hubei Province. The soil was loam with moderate fertility.

[0074] Experimental crop: Rice (Hongnuo No. 1).

[0075] Experimental Design: This experiment included 6 treatments, with 4 replicates per treatment, and each plot was 30 m². 2 The cells are arranged according to a randomized block design, with a 0.5m protective row left in each treatment cell as a spray isolation zone to prevent mutual interference during application.

[0076] Experimental method: The pesticide was applied during the peak hatching period of brown planthopper larvae using a backpack electric sprayer, spraying evenly over the entire rice plant. A shallow water layer of 3-5 cm was maintained in the field during application.

[0077] Survey Methods: Ten sampling points were taken in each plot using a parallel skip sampling method, with two rice clumps surveyed at each point. The initial planthopper population was assessed before pesticide application, and the control effect was assessed again at 3 and 14 days after application. The control effect was calculated based on the planthopper population reduction rate in the pesticide-treated area and the control area.

[0078] The method for calculating drug efficacy is as follows:

[0079]

[0080] The results of the field efficacy trials are shown in the table below:

[0081] Field efficacy trials showed that the rational combination of dimpropyridazine and pyridinequinazolin exhibited high field control efficacy against rice planthoppers. Three days after application, the effective ingredient concentration of each compound formulation was 50 g / hm². 2The efficacy was significantly higher than that of the single-dose control; 14 days after administration, the efficacy of Preparation 6: 28% dimpropyridaz·pyridinequinazoline suspension (3:1) was still above 95%. The efficacy of the compound preparations was significantly higher than that of the single-dose control.

[0082] Example 4: Field efficacy test for controlling tobacco whiteflies.

[0083] Experimental basis: The experiment was conducted in accordance with GB / T 17980.16-2000 "Guidelines for Field Efficacy Tests of Pesticides (I) Control of Greenhouse Whiteflies with Insecticides".

[0084] Experimental site: Vegetable greenhouse in Qin Village, Liyang Town, He County, Anhui Province. The experimental site is flat, with sandy loam soil and moderate fertility.

[0085] Experimental crop: chili pepper.

[0086] Test subject: whitefly.

[0087] Experimental cell arrangement: Each treatment cell has an area of ​​30m². 2 Protective plants were placed around each treatment. All experimental plots were randomly assigned to blocks, with four replicates per treatment. Cultivation and water / fertilizer management conditions were consistent across all experimental plots.

[0088] Application time and method: Apply the pesticide once at the initial stage of whitefly infestation, and apply it once in total during the entire experiment. Use a KeNong 3WBD-20 electric sprayer to evenly spray the stems and leaves on both sides of the plant and the entire area covered by the insect net. Each treatment was covered with a large insect net to prevent whiteflies from flying in from other areas.

[0089] Survey time and method: The number of whiteflies was surveyed and recorded before pesticide application and 3 and 7 days after application. The leaves were inspected in the morning when the adults were not very active. Ten plants in each plot were surveyed without disturbing the insects. The undersides of the leaves must be carefully examined during the survey, and the number of live adults was recorded.

[0090] Methods for calculating drug efficacy:

[0091]

[0092] The results of the field efficacy trials are shown in the table below:

[0093] The experimental results showed that among the five pesticide treatments, Preparation Example 8: 20% dimpropyridaz·pyridinequinazoline wettable powder (1:1) had the best control efficacy against pepper whiteflies, with a control efficacy of 93.96% 7 days after application. The control effect of the compound composition was significantly higher than that of the single-agent control.

[0094] Indoor toxicity tests and field efficacy tests show that the insecticidal composition of the present invention has a significant synergistic effect on lepidopteran pests such as beet armyworm and diamondback moth, hemiptera pests such as rice planthopper and whitefly, and thrips pests such as tsammoth. It is also safe for crops. The dosage of the compound formulation is lower than that of the single-agent control, which significantly reduces agricultural production costs. It has good rapid effect and long-lasting effect.

[0095] Although the present invention has been described in detail above with general description and specific embodiments, some modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. An insecticidal composition containing dimpropyridaz, characterized in that, The insecticidal composition comprises active ingredient A and active ingredient B, wherein active ingredient A is dimpropyridaz and active ingredient B is either chlorfenapyr or pyridinequinazoline, and the mass ratio of active ingredient A to active ingredient B is 1:48 to 50:

1.

2. The insecticidal composition according to claim 1, characterized in that, The mass ratio of dimpropyridaz to chlorfenapyr is 1:32 to 50:1; The mass ratio of dimpropyridaz to pyridinequinazoline is 1:45 to 36:

1.

3. The insecticidal composition according to claim 2, characterized in that, The mass ratio of dimpropyridaz to chlorfenapyr is 1:32 to 30:1; The mass ratio of dimpropyridaz to pyridinequinazoline is 1:30 to 32:1; Preferably, the mass ratio of dimpropyridaz to chlorfenapyr is 1:20 to 30:1; The mass ratio of dimpropyridaz to pyridinequinazoline is 1:35 to 24:

1.

4. The insecticidal composition according to claim 2, characterized in that, The mass ratio of dimpropyridaz to chlorfenapyr is 1:32, 1:24, 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, 30:1, 40:1, or 50:

1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:45, 1:35, 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, 24:1, 32:1, and 36:

1. Preferably, the mass ratio of dimpropyridaz to chlorfenapyr is 1:32, 1:24, 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, or 30:

1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, 24:1, or 32:

1. More preferably, the mass ratio of dimpropyridaz to chlorfenapyr is 1:20, 1:12, 1:10, 1:6, 1:3, 1:1, 2:1, 5:1, 8:1, 15:1, 10:1, 20:1, or 30:

1. The mass ratio of dimpropyridaz to pyridinequinazoline is 1:35, 1:30, 1:25, 1:20, 1:15, 1:10, 1:6, 1:5, 1:1, 3:1, 8:1, 9:1, 12:1, 18:1, and 24:

1.

5. The insecticidal composition according to claim 1, characterized in that, The total weight of the insecticidal composition is 100 wt%, and the combined weight of active ingredient A and active ingredient B accounts for 0.5% to 80% of the total weight of the insecticidal composition.

6. The insecticidal composition according to claim 1, characterized in that, In addition to the active ingredient, the insecticidal composition contains pesticide-acceptable auxiliary ingredients selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, or carriers.

7. The insecticidal composition according to claim 1, characterized in that, The insecticidal composition is prepared as a solid or liquid formulation.

8. The insecticidal composition according to claim 7, characterized in that, The solid formulation is a water-dispersible granule or a wettable powder; the liquid formulation is a suspension concentrate, emulsifiable concentrate, water emulsion, microemulsion, or dispersible oil suspension.

9. Use of the insecticidal composition according to any one of claims 1-8 for the control of crop pests.

10. The use according to claim 9, characterized in that, The pests mentioned are Lepidoptera, Hemiptera, or Thysanoptera. The Lepidoptera pests mentioned are beet armyworm, diamondback moth, cabbage caterpillar, and rice stem borer; the Hemiptera pests mentioned are rice planthopper, aphid, and whitefly; and the Thysanoptera pests mentioned are thrips.

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