Sesame bacterial wilt compound preparation and preparation method thereof

Abstract

The application discloses a kind of sesame bacterial wilt compound medicament and preparation method thereof, belong to plant protection technical field.Sesame bacterial wilt compound medicament of the application, including the following mass percentage of raw materials: thiodipropicolin 20~30%, mesin 10~20%, spreading agent 0.3~0.5%, moisture resistance light decomposition auxiliary agent 2~5%, film-forming slow-release material 1~1.5%, polyglutamic acid 1~1.5%, tea seed meal extract 1~2%, artemisia annua extract 0.5~1%, defoaming agent 0.1~0.2%, the balance is water.The compound medicament of the application can realize the synergistic effect of multi-target point bacteriostasis, plant source synergism, induction resistance and slow-release, can effectively reduce the incidence and disease index of sesame bacterial wilt, improve field control efficiency stability, reduce the frequency of pesticide application and chemical pesticide residue risk, alleviate the problem of the decline of control efficiency caused by long-term single drug.

Description

Technical Field

[0001] This invention relates to the field of plant protection technology, and in particular to a compound agent for treating bacterial wilt of sesame and its preparation method. Background Technology

[0002] Sesame( Indian sesame L. is a traditional and important high-quality oilseed crop. Its seeds have a high oil content, with unsaturated fatty acids (oleic acid and linoleic acid) accounting for about 85%. It is also rich in natural antioxidants such as sesamin, sesamol, and vitamin E, making it an important source of high-quality edible oil and a nutritional health food.

[0003] Sesame bacterial wilt is caused by Ralstonia solanacearum (Ralstonia solanacearum) Ralstonia solanacearum This is a soil-borne disease caused by [unspecified disease]. The climatic conditions during the summer sesame growing season are highly conducive to the occurrence and spread of this disease, with most fields experiencing an incidence rate exceeding 20%. In many severely affected areas, the phenomenon of entire fields being infected and resulting in complete crop failure occurs annually, making it one of the main limiting factors for sesame production.

[0004] Ralstonia solanacearum, due to its high genetic variability, can adapt to a variety of host plants. In sesame, relevant research both domestically and internationally is relatively limited, with existing reports mainly focusing on basic aspects such as pathogen identification, varietal resistance evaluation, and pathogen genetic analysis. Globally cultivated oilseed sesame all originate from the same species, resulting in an extremely narrow genetic background, which severely restricts the breeding of disease-resistant varieties. Currently, researchers have only screened some moderately resistant materials and have not yet discovered highly resistant germplasm resources. Therefore, chemical control remains the primary means of controlling bacterial wilt in current sesame production. Chemical pesticides generally have strong initial efficacy, but they are mostly single-agent applications. Furthermore, with increased application frequency and long-term soil residue, pathogen resistance increases, leading to increasingly poor treatment effectiveness. Therefore, there is an urgent need to develop new compound pesticides to overcome the prominent problems of single-agent pesticides easily inducing pathogen resistance, excessive soil residues, and poor sustained control efficacy. Summary of the Invention

[0005] The purpose of this invention is to provide a compound medicine for treating bacterial wilt of sesame and its preparation method, so as to solve the problems existing in the prior art.

[0006] To achieve the above objectives, the present invention provides the following solution: One of the technical solutions of the present invention is a compound agent for treating bacterial wilt of sesame, comprising the following raw materials in the following mass percentages: 20-30% thiabendazole copper, 10-20% kasugamycin, 0.3-0.5% spreading agent, 2-5% moisturizing and anti-photodegradation agent, 1-1.5% film-forming and slow-release material, 1-1.5% polyglutamic acid, 1-2% tea seed meal extract, 0.5-1% artemisia annua extract, 0.1-0.2% defoamer, with the balance being water.

[0007] Preferably, the thiabendazole copper is a 20% thiabendazole copper suspension; The aforementioned kasugamycin is a 3% kasugamycin wettable powder; The spreading agent includes polyether-modified trisiloxane.

[0008] Preferably, the moisturizing and anti-photodegradation aid includes one or more of glycerin, propylene glycol, and xylitol.

[0009] Preferably, the film-forming sustained-release material includes chitosan and / or amino oligosaccharides.

[0010] Preferably, the method for preparing the tea seed meal extract includes the following steps: The tea seed meal was crushed, mixed with ethanol, heated for extraction, and then filtered to obtain the tea seed meal extract. The tea seed meal extract was mixed with stigmasterol and heated to react, yielding a complex. The complex was mixed with isopropyl ether, heated and stirred to react, filtered and dried to obtain the tea seed meal extract.

[0011] Preferably, the heating extraction temperature is 70~90℃, and the time is 1.5~2.5h; The heating reaction is carried out at a temperature of 70~90℃ for a time of 4.5~5.5h; The heating and stirring reaction is carried out at a temperature of 80~100℃ for 2~3 hours and at a speed of 100~150 rpm.

[0012] Preferably, the preparation method of the artemisia annua extract includes the following steps: Artemisia annua was pulverized, frozen, then rapidly heated, followed by ultrasonic extraction. The extract was filtered, concentrated, and dried to obtain the Artemisia annua extract.

[0013] Preferably, the freezing temperature is -20 to -10°C, and the freezing time is 24 to 26 hours; The heating temperature is 50~55℃; The ultrasonic extraction power is 120~150W, and the time is 20~25min.

[0014] This invention relates to a compound agent for treating bacterial wilt of sesame, which utilizes the synergistic effect of thiabendazole copper and kasugamycin against Ralstonia solanacearum. Thiabendazole copper releases copper ions, disrupting the pathogen's cell membrane structure and inhibiting respiratory metabolism and enzyme activity, while kasugamycin interferes with the pathogen's protein synthesis and cell proliferation. The two agents target different points, achieving rapid and sustained antibacterial action, reducing the dosage of single agents and the risk of drug resistance. The plant-derived antibacterial effect is further enhanced by extracts of tea seed meal and Artemisia annua. Saponins in tea seed meal extract increase the permeability of the pathogen's cell membrane, promoting the entry of active ingredients into the bacterial cell. Artemisia annua extract... The extracts exert natural antibacterial, antioxidant, and resistance-inducing effects, thereby enhancing the overall inhibitory effect of the compound system against bacterial wilt pathogens. Polyglutamic acid improves rhizosphere water and fertilizer retention, promoting root vitality and nutrient absorption, thus enhancing plant resistance and post-disease recovery. A spreading agent improves the spreading and adhesion of the pesticide solution on leaves, stem bases, and rhizosphere surfaces; a moisturizing and photodegradation-resistant adjuvant reduces the photodegradation and inactivation of kasugamycin and plant-derived active ingredients; and a film-forming slow-release material forms a protective film and slowly releases the active ingredients, prolonging the duration of efficacy. Simultaneously, an antifoaming agent improves the stability of formulation processing and spraying. The combined effects of these components achieve a synergistic control effect of direct bactericidal action, plant-derived synergistic effect, resistance induction, rhizosphere protection, and sustained-release efficacy, effectively reducing the incidence of bacterial wilt in sesame, mitigating disease damage, and promoting robust sesame growth, demonstrating significant agricultural application value.

[0015] The second technical solution of the present invention: a method for preparing the above-mentioned compound agent for treating bacterial wilt of sesame, comprising the following steps: Add the film-forming slow-release material to water, let it swell, then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.5~6.8 to obtain the film-forming slow-release mother liquor; Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain the compound agent for treating bacterial wilt of sesame.

[0016] Preferably, the swelling time is 2-4 hours.

[0017] The present invention discloses the following technical effects: The compound agent for treating bacterial wilt of sesame of the present invention has the combined effects of rapid antibacterial activity, sustained disease control, reduced risk of drug resistance, and improved plant stress resistance. It can significantly enhance the inhibitory effect on bacterial wilt of sesame and reduce the risk of drug resistance caused by continuous use of a single agent.

[0018] Compared with traditional single-agent control, the compound agent of this invention can achieve synergistic effects of multi-target antibacterial activity, plant-derived synergistic effect, induction of disease resistance and slow-release effect. It can effectively reduce the incidence and disease index of bacterial wilt in sesame, improve the stability of field control efficacy, reduce the number of applications and the risk of chemical pesticide residues, and alleviate the problem of decreased control efficacy caused by long-term single-agent use. It is suitable for green and efficient control of bacterial wilt in sesame and has good agricultural promotion and application value. Detailed Implementation

[0019] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as a limitation of the present invention, but rather as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0020] It should be understood that the terminology used in this invention is merely for describing particular embodiments and is not intended to limit the invention. Furthermore, with respect to numerical ranges in this invention, it should be understood that each intermediate value between the upper and lower limits of the range is also specifically disclosed. Every smaller range between any stated value or intermediate value within a stated range, and any other stated value or intermediate value within said range, is also included in this invention. The upper and lower limits of these smaller ranges may be independently included or excluded from the range.

[0021] Unless otherwise stated, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. While only preferred methods and materials have been described herein, any methods and materials similar or equivalent to those described herein may be used in the implementation or testing of this invention. All references to this specification are incorporated by way of citation to disclose and describe methods and / or materials associated with those references. In the event of any conflict with any incorporated reference, the content of this specification shall prevail.

[0022] Various modifications and variations can be made to the specific embodiments described in this specification without departing from the scope or spirit of the invention, as will be apparent to those skilled in the art. Other embodiments derived from this specification will also be apparent to those skilled in the art. This specification and embodiments are merely exemplary.

[0023] The terms “include,” “including,” “have,” “contain,” etc., used in this article are all open-ended terms, meaning that they include but are not limited to.

[0024] It should be noted that any aspects not described in detail in this invention are conventional practices in the field and are not the focus of this invention.

[0025] In the specific embodiments of the present invention, the thiabendazole copper used is a 20% thiabendazole copper suspension; the streptomycin is a 3% streptomycin wettable powder; and the thiazolium zinc is a 20% thiazolium zinc suspension; all of which are commercially available products.

[0026] Example 1 A method for preparing a compound agent for treating bacterial wilt of sesame: (1) The compound agent for treating bacterial wilt of sesame is composed of the following raw materials in the following mass percentages: 25% thiabendazole copper, 15% kasugamycin, 0.5% spreading agent, 3% moisturizing and anti-photolysis agent, 1.2% film-forming slow-release material, 1.5% polyglutamic acid, 1.5% tea seed meal extract, 0.8% artemisia annua extract, 0.2% defoamer, and the remainder is water.

[0027] The spreading agent is polyether-modified trisiloxane; The moisturizing and anti-photodegradation agent is glycerin; The film-forming sustained-release material is chitosan.

[0028] (2) Preparation of tea seed meal extract: Tea seed meal was pulverized to 50 mesh to obtain tea seed meal powder; tea seed meal powder and ethanol were mixed at a ratio of 1g:10mL, heated for extraction (temperature 80℃, time 2h), and then filtered to obtain tea seed meal extract. The extract of tea seed meal was mixed with stigmasterol at a ratio of 20 mL: 1 g, heated and reacted (at 80 °C for 4 h), concentrated under vacuum, and dried to obtain the complex. The complex was mixed with isopropyl ether at a ratio of 1 g: 4 mL, and the mixture was heated and stirred (at 100°C for 2 h at 120 rpm). The mixture was then hot-filtered, vacuum concentrated, and dried to obtain tea seed meal extract.

[0029] (3) Preparation of Artemisia annua extract: Fresh Artemisia annua was pulverized and frozen (at -20℃ for 24 hours), then rapidly heated (at 55℃) and subjected to ultrasonic extraction (at 150W for 20 minutes). The extract was filtered, concentrated under vacuum, and dried to obtain Artemisia annua extract.

[0030] (4) Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 3 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0031] Example 2 A method for preparing a compound agent for treating bacterial wilt of sesame: (1) The compound agent for treating bacterial wilt of sesame is composed of the following raw materials in the following mass percentages: 20% thiabendazole copper, 20% kasugamycin, 0.3% spreading agent, 5% moisturizing and anti-photodegradation agent, 1% film-forming slow-release material, 1.5% polyglutamic acid, 1% tea seed meal extract, 1% artemisia annua extract, 0.1% defoamer, and the remainder is water.

[0032] The spreading agent is polyether-modified trisiloxane; The moisturizing and anti-photodegradation additive is propylene glycol; The film-forming sustained-release material is an amino oligosaccharide.

[0033] (2) Preparation of tea seed meal extract: Tea seed meal was pulverized to 50 mesh to obtain tea seed meal powder; tea seed meal powder and ethanol were mixed at a ratio of 1g:10mL, heated for extraction (temperature 70℃, time 2.5h), and then filtered to obtain tea seed meal extract. The extract of tea seed meal was mixed with stigmasterol at a ratio of 20 mL: 1 g, heated to react (temperature 90℃, time 4.5 h), concentrated under vacuum, and dried to obtain the complex. The complex was mixed with isopropyl ether at a ratio of 1 g: 4 mL, and the mixture was heated and stirred (at 80°C for 3 h at 100 rpm). The mixture was then hot-filtered, vacuum concentrated, and dried to obtain tea seed meal extract.

[0034] (3) Preparation of Artemisia annua extract: Fresh Artemisia annua was pulverized and frozen (at -10℃ for 26 hours), then rapidly heated (at 50℃) and subjected to ultrasonic extraction (at 120W for 25 minutes). The extract was filtered, concentrated under vacuum, and dried to obtain Artemisia annua extract.

[0035] (4) Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 4 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photolysis aid, and adjust the pH to 6.5 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0036] Example 3 A method for preparing a compound agent for treating bacterial wilt of sesame: (1) The compound agent for treating bacterial wilt of sesame is composed of the following raw materials in the following mass percentages: 30% thiabendazole copper, 10% kasugamycin, 0.4% spreading agent, 2% moisturizing and anti-photodegradation agent, 1.5% film-forming slow-release material, 1% polyglutamic acid, 2% tea seed meal extract, 0.5% artemisia annua extract, 0.2% defoamer, and the remainder is water.

[0037] The spreading agent is polyether-modified trisiloxane; The moisturizing and anti-photodegradation agent is xylitol; The film-forming sustained-release material is chitosan.

[0038] (2) Preparation of tea seed meal extract: Tea seed meal was pulverized to 50 mesh to obtain tea seed meal powder; tea seed meal powder and ethanol were mixed at a ratio of 1g:10mL, heated for extraction (temperature 90℃, time 1.5h), and then filtered to obtain tea seed meal extract. The extract of tea seed meal was mixed with stigmasterol at a ratio of 20 mL: 1 g, heated to react (temperature 70℃, time 5.5 h), concentrated under vacuum, and dried to obtain the complex. The complex was mixed with isopropyl ether at a ratio of 1 g: 4 mL, and the mixture was heated and stirred (at 90°C for 3 h at 150 rpm). The mixture was then hot-filtered, vacuum concentrated, and dried to obtain tea seed meal extract.

[0039] (3) Preparation of Artemisia annua extract: Fresh Artemisia annua was pulverized and frozen (at -20℃ for 26 hours), then rapidly heated (at 55℃) and subjected to ultrasonic extraction (at 130W for 25 minutes). The extract was filtered, concentrated under vacuum, and dried to obtain Artemisia annua extract.

[0040] (4) Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 2 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photolysis agent, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0041] Comparative Example 1 Same as Example 1, except that the compound medicine for treating bacterial wilt of sesame does not contain tea seed meal extract and artemisia extract.

[0042] Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 3 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0043] Comparative Example 2 Same as Example 1, except that thiabendazole copper is replaced with an equal percentage of thiamethoxam zinc by mass.

[0044] Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 3 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiazole zinc, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0045] Comparative Example 3 Same as Example 1, except that the film-forming sustained-release material is sodium alginate.

[0046] Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material (sodium alginate) to water, let it swell (for 3 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photolysis aid, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0047] Comparative Example 4 Same as Example 1, except that the tea seed meal extract is prepared as follows: Tea seed meal was pulverized to 50 mesh to obtain tea seed meal powder; tea seed meal powder and ethanol were mixed at a ratio of 1g:10mL, and extracted by heating (temperature 70~90℃, time 1.5~2.5h), then filtered, vacuum concentrated and dried to obtain tea seed meal extract.

[0048] Comparative Example 5 Same as Example 1, except that the tea seed meal extract in the sesame bacterial wilt compound agent is replaced with an equal percentage of artemisia annua extract.

[0049] Preparation of compound agents for treating bacterial wilt of sesame: Add the film-forming slow-release material to water, allow it to swell (for 3 hours), then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.8 to obtain the film-forming slow-release mother liquor. Thiamethoxam, kasugamycin, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0050] Comparative Example 6 Same as Example 1, except that the compound agent for treating bacterial wilt of sesame is composed of the following raw materials in the following mass percentages: 25% thiabendazole copper, 15% kasugamycin, and the remainder is water.

[0051] Preparation of compound agents for treating bacterial wilt of sesame: Thiamethoxam and streptomycin are added to water and mixed evenly to obtain a compound agent for treating bacterial wilt of sesame.

[0052] Example 1 The tested sesame variety was Ganheizhi 618 (black sesame). The experiment consisted of 9 treatments, with each treatment replicated 3 times, for a total of 27 plots. Each plot was 30 m² in size. 2 Each plot was arranged using a randomized block designation. The planting plots have been used for sesame cultivation for three consecutive years.

[0053] Before sowing sesame, rotary till the planting area (to a depth of 20cm) and then create ridges (ridges 60cm wide and furrows 25cm wide). Sow two rows of sesame on the ridges, at a density of approximately 200,000 plants / hm². 2 During the sesame seedling stage, spray the sesame bacterial wilt compound agent prepared in Examples 1-3 or Comparative Examples 1-6 on the sesame stems, leaves, and rhizomes. The agent was diluted and sprayed (Examples 1-3 and Comparative Examples 1-5 were diluted 500 times, and Comparative Example 6 was diluted 300 times). 50L of the agent was sprayed per mu. During the initial flowering stage of sesame, spray the sesame bacterial wilt compound agent prepared in Examples 1-3 or Comparative Examples 1-6 on the sesame stems, leaves, and rhizomes again. The agent was diluted and sprayed (Examples 1-3 and Comparative Examples 1-5 were diluted 500 times, and Comparative Example 6 was diluted 300 times). 50L of the agent was sprayed per mu. Routine field management was carried out, and no other disease control agents were applied during this period. A plot without any disease control agents was used as a blank control.

[0054] During the sesame ripening period, the incidence of bacterial wilt was investigated in each plot, and the disease index and control efficacy were calculated; the sesame yield was also statistically analyzed and calculated.

[0055] Sesame bacterial wilt severity classification: Level 0: No disease in the entire plant; Grade 1: 1-2 leaves are wilted or the stem has short, dark brown streaks; Grade 3: Less than 1 / 3 of the plant's leaves are wilted, or the length of the dark brown streaks on the stem is less than 1 / 3 of the stem length; Level 5: 1 / 3 to 2 / 3 of the plant's leaves are wilted, or the length of the dark brown streaks on the stem is 1 / 3 to 2 / 3 of the stem length; Level 7: More than 2 / 3 of the plant's leaves are wilted, or the length of the dark brown streaks on the stem is greater than 2 / 3 of the stem length; Level 9, the diseased plants are basically dead.

[0056] Disease index = ∑ (number of diseased plants at each level × representative value at each level) / (total number of plants surveyed × 9) × 100; Prevention efficacy (%) = (disease index in control area - disease index in treatment area) / disease index in control area × 100%.

[0057] Table 1. Control efficacy against bacterial wilt in sesame. Table 2 Sesame Yield The embodiments described above are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Various modifications and improvements made by those skilled in the art to the technical solutions of the present invention without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.

Claims

1. A compound agent for treating bacterial wilt of sesame, characterized in that, The raw materials include the following percentages by weight: 20-30% thiabendazole copper, 10-20% kasugamycin, 0.3-0.5% spreading agent, 2-5% moisturizing and anti-photodegradation agent, 1-1.5% film-forming slow-release material, 1-1.5% polyglutamic acid, 1-2% tea seed meal extract, 0.5-1% artemisia annua extract, 0.1-0.2% defoamer, and the balance being water.

2. The compound agent for treating bacterial wilt of sesame according to claim 1, characterized in that, The thiabendazole copper is a 20% thiabendazole copper suspension; And / or, the kasugamycin is a 3% kasugamycin wettable powder; And / or, the spreading agent comprises polyether-modified trisiloxane.

3. The compound agent for treating bacterial wilt of sesame according to claim 1, characterized in that, The moisturizing and anti-photodegradation aids include one or more of glycerin, propylene glycol, and xylitol.

4. The compound agent for treating bacterial wilt of sesame according to claim 1, characterized in that, The film-forming sustained-release material includes chitosan and / or amino oligosaccharides.

5. The compound agent for treating bacterial wilt of sesame according to claim 1, characterized in that, The preparation method of the tea seed meal extract includes the following steps: The tea seed meal was crushed, mixed with ethanol, heated for extraction, and then filtered to obtain the tea seed meal extract. The tea seed meal extract was mixed with stigmasterol and heated to react, yielding a complex. The complex was mixed with isopropyl ether, heated and stirred to react, filtered and dried to obtain the tea seed meal extract.

6. The compound agent for treating bacterial wilt of sesame according to claim 5, characterized in that, The heating extraction temperature is 70~90℃, and the time is 1.5~2.5h; And / or, the heating reaction is carried out at a temperature of 70~90℃ for a time of 4.5~5.5h; And / or, the heating and stirring reaction is carried out at a temperature of 80~100℃ for 2~3 hours and at a speed of 100~150 rpm.

7. The compound agent for treating bacterial wilt of sesame according to claim 1, characterized in that, The preparation method of the artemisia annua extract includes the following steps: Artemisia annua was pulverized, frozen, then rapidly heated, followed by ultrasonic extraction. The extract was filtered, concentrated, and dried to obtain the Artemisia annua extract.

8. The compound agent for treating bacterial wilt of sesame according to claim 7, characterized in that, The freezing temperature is -20~-10℃, and the time is 24~26h; And / or, the heating temperature is 50~55°C; And / or, the ultrasonic extraction power is 120~150W, and the time is 20~25min.

9. A method for preparing a compound agent for treating bacterial wilt of sesame according to any one of claims 1 to 8, characterized in that, Includes the following steps: Add the film-forming slow-release material to water, let it swell, then add polyglutamic acid, mix well, add a moisturizing and anti-photodegradation agent, and adjust the pH to 6.5~6.8 to obtain the film-forming slow-release mother liquor; Thiamethoxam, kasugamycin, tea seed meal extract, artemisia annua extract, spreading agent and defoamer are added to the film-forming slow-release mother liquor and mixed evenly to obtain the compound agent for treating bacterial wilt of sesame.

10. The preparation method according to claim 9, characterized in that, The swelling time is 2-4 hours.

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