Compositions for making functional components of aerosol-generating articles, use of functional components to reduce aldehyde ketone content, functional components, and aerosol-generating articles

Abstract

The present application provides a composition for preparing a functional component of an aerosol generating article, comprising: a skeleton component; a binder component; a solvent component; and a functional component; the functional component comprising a compound of Formula 1, wherein R1, R2, R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted aromatic group, substituted or unsubstituted aromatic heterocyclic group, guanidino group, hydroxyl group, alkoxy group, phenolic group, mercapto group, alkylthio group, thiol group, mercapto aromatic group, amino group, alkylamino group, aromatic amino group, alkyl boron group, aromatic boron group, boronic acid group, phosphorus hydrogen group, alkyl phosphorus group, aromatic phosphorus group, alkyl arsenic group, aromatic arsenic group, alkyl silicon group, aromatic silicon group, silicic acid group, alkyl selenium group, aromatic selenium group, alkyl tellurium group, aromatic tellurium group, chlorine atom, bromine atom, iodine atom; and substituted means substituted with a group selected from the group consisting of alkyl, guanidino group, hydroxyl group, amino group, halogen, aromatic group.

Description

Technical Field

[0001] This application relates to the field of tobacco technology, and in particular to a composition for preparing a functional component for aerosol-generating articles, the use of the functional component to reduce aldehyde and ketone content, the functional component, and the aerosol-generating article. Background Technology

[0002] Formaldehyde is a harmful substance that strongly irritates the respiratory system and is classified as a Group 1 carcinogen by the World Health Organization. Traditional tobacco produces large amounts of harmful aldehydes and ketones during combustion, which harm the human body. Although there has been considerable research in the traditional tobacco industry on reducing harmful aldehydes and ketones such as formaldehyde, acetaldehyde, and acrolein, there is still a lack of simple and universally applicable materials that can effectively reduce the content of these harmful aldehydes and ketones.

[0003] With the development of the new tobacco industry, atomized aerosol products (e-cigarettes) and heated tobacco products have become the preferred choice for many people to quit smoking. However, the industry pays very little attention to controlling the harmful aldehyde and ketone content of these new tobacco products. Currently, commercially available new tobacco products typically use propylene glycol and glycerol (glycerin) as atomizing (smoke-generating) agents. Propylene glycol and glycerol easily produce harmful aldehydes and ketones such as formaldehyde when heated to a certain temperature. Although the operating temperature of new tobacco products is generally set at around 200℃, which reduces the harmful aldehyde and ketone content compared to traditional cigarettes, the risk of high formaldehyde content due to changes in product structure or high-frequency inhalation causing localized or instantaneous high temperatures during use cannot be ignored. Furthermore, some flavorings, cooling agents, polymeric excipients, and endogenous substances (such as alcohols, acetals, and carbonyl compounds) from plant components (tobacco or non-tobacco herbs) used in new tobacco products can also undergo pyrolysis and oxidation reactions when heated, producing harmful aldehydes and ketones such as formaldehyde.

[0004] Therefore, there is a need for an improved aerosol-generating article that can solve or mitigate at least one of the problems existing in the prior art. Summary of the Invention

[0005] In view of this, the purpose of this application is to provide a composition for preparing a functional component of an aerosol-generating article, the use of a functional component to reduce the content of harmful aldehydes and ketones in an aerosol-generating article, a functional component, and an aerosol-generating article. The functional component of the aerosol-generating article prepared using the composition of this application can reduce the aldehyde and ketone content of the aerosol-generating article, thus providing safety for the aerosol-generating article.

[0006] A first aspect of this application provides a composition for preparing a functional component of an aerosol-generating article, comprising: a skeleton component; a binder component; a solvent component; and a functional component; wherein the functional component comprises a compound represented by Formula 1.

[0007]

[0008] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to the substitution of a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

[0009] In some embodiments, the functional component includes one or more of arginine, metformin hydrochloride, and guanidinoacetic acid.

[0010] In some embodiments, the content of the functional component is 0.1%-20% based on the total weight of the composition.

[0011] In some embodiments, the skeleton component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components.

[0012] In some embodiments, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin.

[0013] In some embodiments, the inorganic chemical raw material is selected from one or more of metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers.

[0014] In some embodiments, the plant component is selected from one or more of tobacco raw materials, tobacco fragments, tobacco stems, tobacco dust, and aromatic plants.

[0015] In some embodiments, the content of the skeleton component is 10%-90% based on the total weight of the composition.

[0016] In some embodiments, the adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives.

[0017] In some embodiments, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum.

[0018] In some embodiments, the protein-based adhesive includes one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant protein.

[0019] In some embodiments, the polymeric adhesive includes one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether.

[0020] In some embodiments, the content of the adhesive component is 1%-85% based on the total weight of the composition.

[0021] In some embodiments, the solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol.

[0022] In some embodiments, the solvent component comprises 0.1% to 40% of the total weight of the composition.

[0023] In some embodiments, the aerosol generating article is selected from combustible aerosol generating articles, heated non-combustible aerosol generating articles, and / or atomized aerosol generating articles.

[0024] In some embodiments, the functional component is selected from one or more of functional segments and matrix segments.

[0025] In some embodiments, the functional segment is selected from one or more of the following: the fore-plug segment, the cooling segment, the support segment, and the filter segment.

[0026] In some embodiments, the functional component includes micropores.

[0027] In some embodiments, the functional component further includes at least one air passage that extends through at least one end of the functional component along its length.

[0028] In some embodiments, the functional component is integrally formed by an extrusion process.

[0029] A second aspect of this application also provides the use of a functional component to reduce the content of harmful aldehydes and ketones in aerosol-generating articles, said functional component comprising compounds represented by Formula 1.

[0030]

[0031] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to the substitution of a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

[0032] In some embodiments, reducing the content of harmful aldehydes and ketones in aerosol-generating articles includes applying the functional component to a functional part of the aerosol-generating article.

[0033] In some embodiments, applying the functional component to the functional part of the aerosol-generating article includes adding the functional component to the raw material component of the functional part, or spraying or impregnating the functional component with the functional component.

[0034] A third aspect of this application also provides a functional component for an aerosol generating article, wherein, based on the total weight of the functional component, the functional component comprises:

[0035] 4%-98% of the skeletal components;

[0036] 0.01%-95% adhesive components;

[0037] Solvent components of 0.01%-50%; and

[0038] 0.02%-20% of functional components, wherein the functional components include compounds represented by Formula 1.

[0039]

[0040] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

[0041] In some embodiments, the functional component includes one or more of arginine, metformin hydrochloride, and guanidinoacetic acid.

[0042] In some embodiments, the skeleton component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components;

[0043] Preferably, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin;

[0044] The inorganic chemical raw materials are selected from one or more of the following: metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers.

[0045] The plant components are selected from one or more of the following: tobacco raw materials, tobacco leaf fragments, tobacco stems, tobacco dust, and aromatic plants.

[0046] In some embodiments, the adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives;

[0047] Preferably, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum;

[0048] The protein-based adhesives include one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant proteins;

[0049] The polymeric adhesives include one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether.

[0050] In some embodiments, the solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol.

[0051] A fourth aspect of this application also provides an aerosol generating article, the aerosol generating article comprising a functional component prepared using the composition described in the first aspect of this application or a functional component described in the third aspect of this application.

[0052] In some embodiments, the functional component includes a functional segment and a matrix segment, wherein the functional segment is directly or indirectly adjacent to at least one end of the matrix segment along the axial direction.

[0053] In some embodiments, the functional component includes micropores.

[0054] In some embodiments, the functional component further includes at least one air passage that extends through at least one end of the functional component along its length.

[0055] The composition of the functional component for preparing aerosol-generating articles of this application includes a compound of Formula 1 as a functional component. In the compound of Formula 1, the amino group attached to a carbon atom of the guanidinium group has a strong affinity and can interact with… The group undergoes an affinity addition reaction to generate a hydroxylamine intermediate. The hydroxyl group in the hydroxylamine intermediate undergoes a dehydration reaction with a hydrogen atom on an adjacent nitrogen atom to generate a product containing a carbon-nitrogen double bond. Therefore, the functional component in the composition of this application can remove aldehydes and ketones generated in aerosol-generating articles, improving the safety of the aerosol-generating articles. The composition of this application can be used to prepare functional components of aerosol-generating articles, such as filtration sections, cooling sections, support sections, pre-plug sections, and / or media sections. This makes it applicable to various types of aerosol-generating articles, reducing aldehydes and ketones at different functional sites, and further improving the safety of aerosol-generating articles. Attached Figure Description

[0056] Figure 1 This is a schematic diagram of the structure of an aerosol-generating article according to an embodiment of this application.

[0057] Figure 2 This is a schematic diagram of the structure of an aerosol-generating article according to another embodiment of this application.

[0058] Figure 3 This is a schematic diagram of the structure of an aerosol-generating article according to another embodiment of this application.

[0059] Figure 4 This is a schematic diagram of the structure of an aerosol-generating article according to another embodiment of this application.

[0060] Figure 5 This is a structural schematic diagram of a matrix segment or functional segment in an embodiment of this application, along a cross section perpendicular to the length direction.

[0061] Figure 6 This is a structural schematic diagram of a matrix segment or functional segment in another embodiment of this application, along a cross section perpendicular to the length direction.

[0062] Figure 7 This is a structural schematic diagram of a matrix segment or functional segment in a cross section perpendicular to the length direction, according to another embodiment of this application. Detailed Implementation

[0063] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. It should be understood that the described embodiments and drawings are only a part of the embodiments of this application, and not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0064] Throughout this specification, unless otherwise specified, the terminology used herein should be understood as having the meaning commonly used in the art. Therefore, unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains. In the event of any conflict, this specification shall prevail.

[0065] It should be noted that, in the embodiments of this application, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a method or apparatus that includes a list of elements includes not only the elements expressly stated, but also other elements not expressly listed, or elements inherent to implementing the method or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other related elements in the method or apparatus that includes that element.

[0066] It should be noted that the terms "first," "second," and "third" used in the embodiments of this application are merely to distinguish similar objects and do not represent a specific ordering of objects. It is understood that "first," "second," and "third" can be interchanged in a specific order or sequence where permitted. It should be understood that the objects distinguished by "first," "second," and "third" can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in an order other than those described herein.

[0067] Traditional combustible tobacco produces large amounts of harmful aldehydes and ketones during combustion. Solvents, flavorings, and other additives in new tobacco products also produce harmful aldehydes and ketones during heating, posing a threat to human health. Therefore, it is necessary to improve aerosol-generating products by reducing their aldehyde and ketone content to enhance their safety.

[0068] In view of this, the first aspect of this application provides a composition for preparing a functional component of an aerosol-generating article. The functional component of the aerosol-generating article prepared using the composition of this application can reduce aldehydes and ketones generated during heating of the aerosol-generating article.

[0069] The composition of this application comprises: a skeleton component; a binder component; a solvent component; and a functional component; wherein the functional component comprises a compound represented by Formula 1.

[0070]

[0071] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to the substitution of a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

[0072] In this application, the functional component is a "porous structure," which refers to a structure with high porosity. This ensures efficient aerosol generation, and the interconnected pores form a three-dimensional network structure, which helps reduce suction resistance. In this application, the "porous structure" is a microporous structure. Micropores are formed by the gaps between the components of the composition after the aforementioned composition for preparing the structural segment is formed. These micropores are irregular and belong to the pores in a microscopic sense. The size of the micropores is determined by the gaps between the powder components after the powder is formed.

[0073] In this application, the composition includes a compound of Formula 1, which reacts with aldehydes and ketones according to the chemical reaction shown below. Specifically, the compound of Formula 1 includes a guanidinium group, in which the amino group (-NH2) attached to a carbon atom has a high electron cloud density and exhibits nucleophilicity. Among the aldehydes and ketones, In groups such as aldehydes (-CHO), the high electronegativity of oxygen atoms gives the carbonyl carbon a partial positive charge, making it electrophilic. The lone pair of electrons on the nitrogen atom of the guanidinium group attacks the carbonyl carbon of the aldehyde group, forming a new carbon-nitrogen single bond. Simultaneously, the π bond of the carbonyl group opens, transferring electrons to the oxygen atom, forming a negatively charged oxygen ion intermediate. This results in a nucleophilic addition reaction, generating the hydroxylamine intermediate. Further, in the generated hydroxylamine intermediate, the hydroxyl group (-OH) can undergo a dehydration reaction with the hydrogen atom on the adjacent nitrogen atom. Because the lone pair of electrons on the nitrogen atom can form a hydrogen bond with the hydroxyl hydrogen, the hydroxyl hydrogen leaves as a proton. Simultaneously, a double bond forms between the nitrogen atom and the adjacent carbon atom, removing a water molecule, ultimately generating a product containing a carbon-nitrogen double bond (C=N).

[0074]

[0075] Furthermore, the compound represented by Formula 1 in this application can reduce the formation of harmful aldehydes and ketones by inhibiting free radical reactions. The reaction principle is as follows: In the compound represented by Formula 1, the carbon in the guanidinium group and the three nitrogen atoms attached to it form an electron-rich conjugated system; while the various components in the aerosol-generated products (such as tobacco, or non-tobacco herbs, solvents such as propylene glycol, glycerol, etc., flavoring components such as menthol, etc.) produce precursors or intermediates (such as methyl radicals) that can directly or promote the formation of harmful aldehydes and ketones when heated. These precursors or intermediates are relatively electron-deficient. Therefore, the guanidinium group in the compound of Formula 1 can easily combine with the precursors or intermediates of harmful aldehydes and ketones, thereby stabilizing the free radicals and blocking the further reaction of the free radicals to form harmful aldehydes and ketones (such as the oxidation of methyl radicals to formaldehyde).

[0076] For the reasons stated above, the functional components in the composition of this application can achieve the purpose of removing aldehydes and ketones. Therefore, the functional components of the aerosol generating articles prepared using the composition of this application can reduce the content of harmful aldehydes and ketones in the aerosol generating matrix and improve the safety of the aerosol generating articles.

[0077] In this application, alkyl refers to a group having a C12 or C232-242-3 ... n H 2n+1 A straight-chain or branched saturated hydrocarbon group of the general formula is a group formed by removing one hydrogen atom from a straight-chain or branched alkane. C1-C20 alkyl groups (where n is an integer from 2 to 20) represent alkyl groups having 1 to 20 carbon atoms as shown. Examples of C1-C20 alkyl groups include, but are not limited to, methyl, ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, isopropyl, tert-butyl, sec-butyl, isobutyl, cyclopropyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl, etc.

[0078] In this application, the term "aromatic group" refers to an aromatic group having "4n+2" (π) electrons and 6 to 22 ring atoms in a conjugated monocyclic or polycyclic system (fused or unfused), where n is an integer from 1 to 5. The polycyclic system includes at least one aromatic ring. Aryl groups can be directly linked or linked via C1-C3 alkyl groups (also called arylalkyl or aralkyl groups). Examples of aryl groups include, but are not limited to, phenyl, benzyl, phenethyl, 1-phenylethyl, tolyl, naphthyl, biphenyl, terphenyl, indene, benzocyclooctenyl, benzocycloheptenyl, azulel, acenaphthel, fluorenyl, phenanthrene, anthracene, etc. The term aryl includes both unsubstituted and substituted aryl groups.

[0079] In this application, the term "aromatic heterocyclic group" refers to a heterocycle with planar structural characteristics, in which the atoms in the ring form a closed conjugated system, the molecule is planar, and there are ring-shaped delocalized electron clouds on both sides of this plane. The number of p electrons in the conjugated system all conforms to Hückel's rule. Examples of aromatic heterocyclic groups include, but are not limited to, pyridyl, bipyridyl, pyrazinyl, bipyrazinyl, (bi)triazinyl, (bi)isotriazinyl, (bi)pyrimidinyl, (bi)pyrroleyl, porphyrinyl, purine, indazole, etc.

[0080] In this application, the "aldehyde and ketone content" can be measured using the following exemplary method. Specifically, simulated smoking is performed using a fully automatic rotary heated non-combustible cigarette smoking machine (Puffman-X500E-L). An aerosol trap is used to collect the aerosol, and the content of aldehydes and ketones (e.g., formaldehyde, acetaldehyde, acrolein) in the aerosol is measured using chromatographic methods, such as high-performance liquid chromatography (HPLC).

[0081] In some embodiments, the compound 1 is selected from arginine, metformin hydrochloride, and guanidinoacetic acid. All of these compounds contain a guanidinyl group, which can react with harmful aldehydes and ketones in aerosols, thereby reducing the content of harmful aldehydes and ketones in aerosol-generated products and improving their safety. Furthermore, arginine and guanidinoacetic acid are naturally occurring guanidinyl-containing substances that can be easily synthesized using chemical or bioengineering methods, making them inexpensive and safe. Metformin hydrochloride is a common diabetes drug and has also been found to have weight-loss and longevity-promoting effects. Its synthesis is simple and inexpensive, and metformin has a double guanidinyl group in its chemical structure, resulting in a higher electron cloud density, which is more conducive to condensation with aldehydes and ketones or inhibition of free radical reactions. These compounds are representative substances that have been extensively studied and applied in the life sciences field, with the most extensive time and sample size, possessing high safety, low cost, and ease of promotion and application.

[0082] In some embodiments, the content of the functional component, based on the total weight of the composition, is 0.1%-20%. By keeping the content of the functional component within this range, it is beneficial for the functional component to fully react with aldehydes and ketones generated during heating of the aerosol-generating article, thereby effectively reducing the content of aldehydes and ketones and improving the safety of the aerosol-generating article. Exemplarily, the content of the functional component, based on the total weight of the composition, can be 0.1%, 1%, 5%, 10%, 12%, 14%, 16%, 18%, 20%, or a value within a range of any two of these values.

[0083] In some embodiments, the framework component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components. The framework component provides a framework for the functional components of the aerosol-generated article, thereby facilitating the molding of the raw material components and providing a carrier for other raw material components in the functional components.

[0084] In some embodiments, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin. These organic chemical raw materials have a relatively long chain-like molecular structure, capable of forming microfibrils. These microfibrils interconnect to form a robust network structure, resulting in a skeleton with good mechanical strength and stability. Furthermore, the network structure formed by these organic chemical raw materials has abundant porosity, providing attachment sites for other raw material components, which is beneficial for improving the quality of aerosol-generated products. In addition, these renewable chemical raw materials are widely available, inexpensive, and produce very few harmful substances during heating, further enhancing the safety of aerosol-generated products.

[0085] In some embodiments, the inorganic chemical raw material is selected from one or more of metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers. These inorganic chemical raw materials have good processing properties, facilitate composition molding, and can provide a mechanically sound framework for functional components.

[0086] In some embodiments, the plant component is selected from one or more of tobacco raw materials, tobacco fragments, tobacco stems, tobacco dust, and aromatic plants. On the one hand, the above-mentioned plant components can provide a natural supporting framework. On the other hand, endogenous substances in the plant components, such as nicotine, enter the human bloodstream, promote the pituitary gland to produce dopamine, thereby obtaining physiological satisfaction, or can provide tobacco aroma or other flavor aromas to aerosol-generated products, enhancing the user's sensory experience. In some embodiments, the aromatic plants are selected from one or more of tea leaves, thyme, osmanthus, lemon, lavender, and benzoin. Optionally, the plant component is selected from tobacco raw materials. There are no particular limitations on the form of the above-mentioned plant components, and forms commonly used in the art can be used. For example, the above-mentioned plant components can be in powder form after being crushed.

[0087] In some embodiments, the content of the skeleton component is 10%-90% based on the total mass of the composition. By keeping the content of the skeleton component within the above range, a robust and stable supporting skeleton is provided for the aerosol-generating matrix, and a carrier is provided for other components, etc. Exemplarily, the content of the skeleton component based on the total mass of the composition can be 10%, 20%, 30%, 40%, 50%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, or a value between any two of these values.

[0088] In some embodiments, the adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives. The adhesive component achieves close contact by wetting the interfaces of the various component materials in the composition, generating intermolecular attraction, thereby binding the powders, liquids, etc., of the component materials. The aforementioned adhesive component can bind the various components in the composition to form a stable structure and exhibits good biocompatibility.

[0089] In some embodiments, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum.

[0090] In some embodiments, the protein-based adhesive includes one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant protein.

[0091] In some embodiments, the polymeric adhesive includes one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether.

[0092] In some embodiments, the content of the adhesive component, based on the total weight of the composition, is 1%-85%. Maintaining the content of the adhesive component within this range facilitates the formation of a robust and stable structure in the composition. Exemplarily, the content of the adhesive component, based on the total weight of the composition, can be 1%, 2%, 5%, 8%, 10%, 12%, 15%, 20%, 30%, 40%, 50%, 60%, 65%, 70%, 75%, 80%, 85%, or a value within a range of any two of these values.

[0093] In some embodiments, the solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol. The solvent component facilitates the uniform dispersion of the functional components within the functional parts of the aerosol-generating article, allowing harmful substances released from the aerosol-generating article (e.g., precursors or intermediates of harmful aldehydes and ketones, catalysts, etc.) to fully contact and react with the functional substances, thereby reducing the content of harmful aldehydes and ketones. This application does not impose specific limitations on the specific composition of the solvent component; those skilled in the art can adjust the specific composition of the solvent according to the function of the prepared functional part. For example, when the functional part is the matrix segment in the aerosol-generating article, the solvent component includes at least one of propylene glycol or glycerol.

[0094] In some embodiments, the solvent component content is 0.1%-40% based on the total weight of the composition. Maintaining the solvent component content within this range facilitates the formation of a stable structure in the composition and promotes uniform dispersion of the functional components. Exemplarily, the solvent component content, based on the total weight of the composition, can be 0.1%, 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, or a value within a range of any two of these values.

[0095] In some embodiments, the aerosol generating article is selected from combustible aerosol generating articles, heated non-combustible aerosol generating articles, and / or atomized aerosol generating articles.

[0096] In some embodiments, the functional component is selected from one or more of functional segments and matrix segments.

[0097] In some embodiments, the functional segment is selected from one or more of the following: the fore-plug segment, the cooling segment, the support segment, and the filter segment.

[0098] In some embodiments, the functional component includes micropores. Micropores refer to the gaps between the components that form microscopic pores after the composition used to prepare the functional component is molded. This facilitates the formation of aerosols.

[0099] In some embodiments, the cross-sectional area of ​​the micropore is 0.7 nm. 2 ~710μm 2 Alternatively, the hydraulic diameter of the micropores is 10 nm to 30 μm.

[0100] In some embodiments, the cross-sectional area of ​​the micropore is 1963 nm. 2 ~20μm 2 Alternatively, the hydraulic diameter of the micropores is 50 nm to 5 μm.

[0101] In some embodiments, the functional component further includes an air passage that extends through at least one end of the functional component along its length. This improves the air permeability of the functional component.

[0102] In some embodiments, the air passage extends through opposite ends of the functional component along its length.

[0103] In some embodiments, the functional component has multiple air passages inside.

[0104] In some embodiments, the cross-sectional shape of the air passage is circular, elliptical, racetrack-shaped, fan-shaped, or polygonal in a plane perpendicular to the length direction of the functional component.

[0105] In some embodiments, the cross-sectional area of ​​the airway orifice is 0.0019 mm. 2 -30mm 2 Alternatively, the hydraulic diameter of the airway orifice is 0.05mm-6mm.

[0106] In some embodiments, the wall thickness of the spacer wall between adjacent airway openings is 10 μm to 800 μm.

[0107] In some embodiments, the functional component is integrally formed using an extrusion process. This integrally formed functional component overcomes the problems of filament shedding, residue, and difficulty in cleaning that occur during the suction process of aerosol-generating products. This improves the user experience.

[0108] In this application, "extrusion process" refers to a processing method in which a raw material composition is added to an extruder, and the material is heated and plasticized while being pushed forward by the screw through the extruder barrel and screw, continuously passing through the die head to form products or semi-finished products of various cross-sections. The functional components formed by extrusion molding are strip-shaped. Because the functional components, such as the aerosol generating matrix, are an integral structure, they remain a unified medium after the aerosol generating product is heated and absorbed or after heating ceases, preventing disintegration and falling off. This helps reduce problems such as filament shedding, residue shedding, and difficulty in cleaning.

[0109] A second aspect of this application also provides the use of a functional component to reduce the content of harmful aldehydes and ketones in aerosol-generating articles, said functional component comprising compounds represented by Formula 1.

[0110]

[0111] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboryl, aromaticboryl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine, bromine, and iodine atoms; substitution refers to substitution by groups selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups. As described above, the functional components of this application can reduce or even remove aldehydes and ketones generated when the aerosol-generating product is heated, thereby improving the safety of the aerosol-generating product.

[0112] In some embodiments, reducing the content of harmful aldehydes and ketones in the aerosol-generating product includes applying the functional component to a functional part of the aerosol-generating product. In some embodiments, applying the functional component to the functional part of the aerosol-generating product includes adding the functional component to the raw material component of the functional part, or spraying or impregnating the functional component with the functional component. By mixing the functional component with the raw material component of the functional part to form a slurry, and then preparing it through an integral molding process, the functional component is better dispersed uniformly in the functional part, allowing it to fully contact the aldehydes and ketones generated during heating of the aerosol-generating product, thereby reducing harmful aldehydes and ketones. By spraying or impregnating the functional component with the prepared functional part, a functional layer for removing aldehydes and ketones can be formed on the surface of the functional part; the preparation method is simple and cost-effective. It is understood that those skilled in the art can choose an appropriate application method as needed.

[0113] A third aspect of this application also provides a functional component, wherein the functional component comprises, based on its total weight:

[0114] 4%-98% of the skeletal components;

[0115] 0.01%-95% adhesive components;

[0116] Solvent components of 0.01%-50%; and

[0117] 0.02%-20% of functional components, wherein the functional components include compounds represented by Formula 1.

[0118]

[0119] In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

[0120] In this application, by including the above-mentioned components in the functional components, it is beneficial for the functional components to form a stable integral structure, and the functional components therein can reduce the content of harmful aldehydes and ketones generated in the aerosol-generating products, thereby improving the safety of the aerosol-generating products.

[0121] Those skilled in the art will understand that the components in the functional parts of this application have similar characteristics to the components in the composition for preparing the functional parts described in the first aspect of this application. When preparing a functional part for aerosol generation articles using the composition of the first aspect of this application, during the molding process, due to reasons such as heating, easily volatile substances in the composition, such as solvent components, are lost. Therefore, the mass percentage of each component in the prepared functional part differs from the mass percentage of each component in the raw material composition.

[0122] In some embodiments, the functional component includes one or more of arginine, metformin hydrochloride, and guanidinoacetic acid.

[0123] In some embodiments, the skeleton component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components;

[0124] Preferably, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin;

[0125] The inorganic chemical raw materials are selected from one or more of the following: metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers.

[0126] The plant components are selected from one or more of the following: tobacco raw materials, tobacco leaf fragments, tobacco stems, tobacco dust, and aromatic plants.

[0127] In some embodiments, the adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives;

[0128] Preferably, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum;

[0129] The protein-based adhesives include one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant proteins;

[0130] The polymeric adhesives include one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether.

[0131] In some embodiments, the solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol. A fourth aspect of this application also provides an aerosol-generating article comprising a functional component prepared using the composition described in the first aspect of this application or the functional component described in the third aspect of this application. This is advantageous in reducing the generation of harmful aldehydes and ketones during heating of the aerosol-generating article, thereby improving the safety of the aerosol-generating matrix. The number of functional components prepared using the composition of this application in the aerosol-generating article is not limited; those skilled in the art can choose any functional component prepared using the composition of this application as needed.

[0132] Aerosol generating products are used in conjunction with aerosol generating devices, which include heating components and power supply components. The power supply components provide electrical energy to the heating components, which convert the electrical energy into other forms of energy and apply them to the aerosol generating matrix in the matrix section, thereby heating the aerosol generating matrix to generate aerosols for users to inhale.

[0133] In some embodiments, the functional component includes a functional segment and a matrix segment, wherein the functional segment is directly or indirectly adjacent to at least one end of the matrix segment along the axial direction.

[0134] The following is in conjunction with the appendix Figure 1-4 The structure of the aerosol-generating article of this application is illustrated by way of example.

[0135] In some implementations, reference Figures 1 to 2 The aerosol generating article includes a matrix segment 20, a functional segment 30, and an encapsulation layer (not shown). The encapsulation layer covers the circumferential exterior of the functional segment and the aerosol generating matrix.

[0136] The matrix segment 20 has two axial ends, namely a proximal lip end 20a and a distal lip end 20b. The proximal lip end 20a refers to the end of the matrix segment 20 that is closer to the user's lips when the user uses the aerosol-generated product, and the distal lip end 20b refers to the end of the matrix segment 20 that is farther away from the user's lips when the user uses the aerosol-generated product.

[0137] This application does not limit the specific structure of the functional section 30, which includes at least one of the following: the front plug section 10, the filter section 31, the support section 32, and the cooling section 33.

[0138] The coating layer can protect the aerosol-generating matrix. The coating layer includes, but is not limited to, one or more of the following materials: fiber paper, metal foil, metal foil composite fiber paper, polyethylene composite fiber paper, polyethylene (PE), polybutylene terephthalate (PBAT).

[0139] In some implementations, please refer to Figure 1 and Figure 2 The functional section 30 includes one or more of the following: a filter section 31, a support section 32, and a cooling section 33. The functional section is located near the lip end 20a of the matrix section 20.

[0140] In some implementations, such as Figure 1 As shown, the functional segment 30 includes a filter segment 31, which is disposed near the lip end 20a of the matrix segment 20 along its axial direction. The aerosol generated by the aerosol generating matrix is ​​transported to the filter segment under suction negative pressure. The filter segment is used to filter and / or adsorb some particulate matter and harmful substances in the aerosol, improving the user's suction experience and enhancing the safety of the aerosol-generated products. Furthermore, the process of the aerosol being loosened by the filter segment before reaching the user can reduce the temperature of the aerosol, mitigating the "burning" sensation when the user inhales the aerosol.

[0141] In some implementations, such as Figure 2 The functional section includes a filter section 31, a support section 32, and a cooling section 33. The support section 32 is located at one end of the matrix section 20 along its axial direction, one end of the cooling section 33 is located at the end of the support section 32 away from the matrix section 20 along its axial direction, and the filter section 31 is located at the other end of the cooling section 33.

[0142] The support section 32 can connect and support the matrix section 20 and the cooling section 33 at both ends. The cooling section 33 is used to reduce the temperature of the aerosol so that the temperature of the aerosol flowing out of the filter section 31 is suitable and avoids the problem of the aerosol being "hot to the mouth".

[0143] Of course, the positions of the support section and the cooling section can also be interchanged, that is, the cooling section 33 is connected to one end of the matrix section 20 along the axis, and the two ends of the support section 32 are connected to the other end of the cooling section 33 and the filter section 31, respectively.

[0144] In some implementations, reference Figure 3 and Figure 4 The functional section 30 includes one or more of the following: a pre-plug section 10, a filter section 31, a support section 32, and a cooling section 33. One or more of the filter section 31, support section 32, and cooling section 33 are disposed at one end of the aerosol generating matrix 20 along its length, and the pre-plug section is disposed at the other end of the aerosol generating matrix 20 along its length. The encapsulation layer wraps around the circumferential exterior of the functional section and the matrix section. The pre-plug section improves the problem of aerosol generating matrix 20 detachment. Furthermore, the pre-plug section 10 can adsorb the condensed and refluxed aerosol after the aerosol generating product stops pumping, thereby avoiding the problem of aerosol condensation flowing downwards and causing internal contamination of the aerosol generating device, making it difficult to clean, and preventing cross-contamination of flavors when pumping different flavored aerosol generating products.

[0145] In some implementations, such as Figure 3As shown, the aerosol generating article includes a pre-plug section 10, a matrix section 20, a cooling section 33, a filter section 31, and a coating layer (not shown). The pre-plug section is located at the distal lip end 20b of the aerosol generating matrix, the cooling section is located at the proximal lip end 20a of the aerosol generating matrix, and the filter section is located at the other end of the cooling section away from the aerosol generating matrix.

[0146] In some implementations, such as Figure 4 As shown, the aerosol generating article includes a pre-plug section 10, a matrix section 20, a support section 32, a cooling section 33, a filter section 31, and a coating layer. The pre-plug section is located at the distal lip end 20b of the aerosol generating matrix, the support section 32 is located at the proximal lip end 20a of the aerosol generating matrix, and the cooling section 33 is located at the end of the support section 32 axially away from the aerosol generating matrix 20. The filter section 31 is located at the end of the cooling section 33 axially away from the support section 32.

[0147] This application does not limit the structure of the functional segments and / or matrix segments. In some exemplary embodiments, such as Figure 5 As shown, the functional segment and / or matrix segment itself has numerous micropores, which are interconnected to form micro-channels. It can be understood that after the functional segment is formed, the gaps between its raw material components constitute micropores. These micropores are irregular and belong to the category of pores in a microscopic sense. The size of the micropores is determined by the gaps between the powder components after powder forming.

[0148] During the aerosol generation process, the generated aerosols can enter the microchannels of the functional section. Under the negative pressure generated by suction, the aerosols are transported to the user for inhalation through the microchannels. In addition, as the aerosols flow through the microchannels, it also helps the functional section capture some substances in the aerosols and has a cooling effect.

[0149] In some embodiments, the cross-sectional area of ​​the micropore is 0.7 nm. 2 ~710μm 2 Alternatively, the hydraulic diameter of the micropore is 10 nm to 30 μm. In this application, the hydraulic diameter refers to the ratio of four times the cross-sectional area of ​​the flow passage to the perimeter.

[0150] In some embodiments, the cross-sectional area of ​​the micropore is 1963 nm. 2 ~20μm 2 Alternatively, the hydraulic diameter of the micropores is 50 nm to 5 μm.

[0151] In some embodiments, the pre-plug section and the filter section themselves have numerous micropores, which are interconnected to form micro-air channels.

[0152] In other exemplary embodiments, such as Figure 6 and Figure 7As shown, the functional segment and / or matrix segment include micropores and at least one airway pore, which penetrates at least one end of the structural segment along its length. The airway pore helps improve the air permeability of the functional segment and reduce suction resistance.

[0153] It should be noted that the airway pores mentioned above are pores in a macroscopic sense, while micropores are pores in a microscopic sense. The cross-sectional area of ​​an airway pore is much larger than that of a micropore, for example, at least 20 times larger.

[0154] In some embodiments, the cross-sectional area of ​​the airway pores is 20 to 60,000 times that of the micropores. This is beneficial for balancing the structural stability of the structural segment and the aerosol release rate. In some embodiments, the cross-sectional area of ​​the airway pores is 100 to 40,000 times that of the micropores.

[0155] The micro-airways are connected to the airway pores. Since the micro-airways are formed by the interconnection of micropores, the micropores are also connected to the airway pores. Furthermore, it can be understood that the interconnection between micropores can be partial, with some micropores not connected, or all micropores can be interconnected. A portion of the aerosol in the micro-airways can also be collected at the airway pores and delivered to the user's mouth under the negative pressure of suction. The airway pores help reduce the suction resistance for the user, improving the user experience. It should be noted that suction resistance is positively correlated with the flow resistance of the aerosol; the lower the flow resistance of the aerosol, the lower the perceived suction resistance, and vice versa.

[0156] In some embodiments, the airway opening extends through both ends of the functional segment and / or matrix segment along its length. This helps to reduce suction resistance for the user.

[0157] In one implementation, such as Figure 6 As shown, the functional segment and / or matrix segment has an airway opening inside. This helps to reduce the suction resistance for the user.

[0158] In some implementations, such as Figure 7 As shown, the functional segment and / or matrix segment have multiple airway pores inside. This is more conducive to reducing the suction resistance for the user.

[0159] In some embodiments, the cross-sectional shape of the airway opening is circular, elliptical, racetrack-shaped, fan-shaped, or polygonal in a plane perpendicular to the length direction of the functional segment and / or matrix segment.

[0160] In some embodiments, the cross-sectional area of ​​the airway orifice is 0.0019 mm. 2 -30mm 2Alternatively, the hydraulic diameter of the airway orifice is 0.05 mm to 6 mm. In some preferred embodiments, the cross-sectional area of ​​the airway orifice is 0.007 mm². 2 ~7.1mm 2 (square millimeters). In some preferred embodiments, the hydraulic diameter of the airway orifice is 0.1 mm to 3 mm. This facilitates more uniform aerosol release and higher utilization.

[0161] In some embodiments, the wall thickness of the spacer wall between adjacent air passages is 10 μm to 800 μm. This facilitates heat penetration and diffusion, resulting in higher heat transfer efficiency, while also maintaining structural strength.

[0162] It should be noted that the matrix section included in the aerosol generating product is used to generate aerosols, while the filtration section, cooling section, support section, and fore-plug section do not generate aerosols.

[0163] This application also provides an aerosol generation system. The aerosol generation system includes an aerosol generation apparatus with a heating component and the aerosol generation article described above. Specifically, the heating component heats and atomizes the aerosol generation matrix to generate aerosols.

[0164] The present application will be described in further detail below with reference to specific embodiments. The purpose of this description is merely illustrative and not intended to limit the scope of this disclosure.

[0165] Example

[0166] All non-tobacco raw materials used in the following examples are commercially available.

[0167] In the following examples, a screw extruder is used to extrude the raw material composition to obtain functional components.

[0168] Example 1

[0169] A commercially available tobacco-flavored solid heated non-combustible aerosol generating product (TEREA cigarette, purchased from IQOSILUMA, model: SINNA, comprising a pre-stop section, matrix section, support section, cooling section, and filter section) was disassembled, and the aerosol generating medium (matrix section) was extracted and pulverized as a skeleton component (hereinafter referred to as pulverized medium). 60 parts by weight of the pulverized medium, 15 parts by weight of the gelatin binder, 5 parts by weight of the propylene glycol and 19.9 parts by weight of the glycerol solvent, and 0.1 parts by weight of the metformin hydrochloride functional component were weighed and mixed evenly to obtain a composition for preparing the aerosol generating matrix. The resulting composition was extruded to obtain a functional component, which was used as the matrix section in the aerosol generating product. The prepared matrix section replaced the matrix section in the existing heated non-combustible aerosol generating product to prepare the aerosol generating product of this application.

[0170] Examples 2-6

[0171] The aerosol generating articles were prepared in a manner similar to that of Example 1, except that the types and weights of the components in the composition used to prepare the aerosol generating matrix were adjusted according to the formulations described in Table 1.

[0172] Comparative Example 1

[0173] Commercially available tobacco-flavored solid heated non-combustible aerosol generating products (TEREA).

[0174] Table 1: Composition formulations for preparing aerosol generation matrices

[0175]

[0176] The aerosol-generated products of Examples 1-6 and Comparative Example 1 were tested according to the following method.

[0177] Measurement of aldehyde and ketone content

[0178] The aerosol-generated product was simulated for inhalation using a fully automatic rotary heated non-combustible cigarette smoking machine (Puffman-X500E-L). The inhalation parameters were set as follows: inhalation volume of 55ml, inhalation time of 2s, inhalation interval of 28s, number of puffs of 10, and an inhalation curve of bell shape. An aerosol trap (specifically a Whatman 44mm Cambridge filter (F319-04)) was used to collect the aerosols. The content of formaldehyde, acetaldehyde, and acrolein in the collected aerosols was measured using high-performance liquid chromatography (HPLC). The HPLC test parameters included:

[0179] 2,4-Dinitrophenylhydrazine was used as an indicator;

[0180] Detection wavelength: 365nm;

[0181] Mobile phase A: water-acetonitrile-tetrahydrofuran-isopropanol (59:30:10:1);

[0182] Mobile phase B: water-acetonitrile (35:65);

[0183] Column temperature: 30℃;

[0184] Injection volume: 2 μL;

[0185] Mobile phase elution gradient: see Table 2 below.

[0186] Table 2

[0187] Time (min) Flow rate (mL / min) Mobile phase A (%) Mobile phase B (%) 0 0.4 100 0 12 0.4 60 40 15 0.4 10 90 18 0.4 90 10 20 0.4 100 0 25 0.4 100 0

[0188] Understandably, to save on testing costs and to provide a direct comparison of changes in aldehyde and ketone content, only the contents of formaldehyde, acetaldehyde, and acrolein were measured. These three aldehydes are common harmful substances produced in aerosol-generating products, and changes in their content can effectively reflect changes in the content of harmful aldehydes and ketones produced in aerosol-generating products. The test results are shown in Table 3 below.

[0189] Table 3

[0190]

[0191] The results above show that, compared to Comparative Example 1, Examples 1-6, which use the compositions of this application to prepare aerosol generating matrices, including functional components of this application such as L-arginine, metformin hydrochloride, and guanidinoacetic acid, effectively reduce the content of aldehydes and ketones during the aerosol generation process. Examples 1-4 demonstrate that the effect of reducing harmful aldehydes and ketones in aerosol generating products gradually increases with the increase of functional component content.

[0192] Example 7

[0193] 50 parts by weight of kudzu root powder, 10 parts by weight of gelatin (binder component), 2 parts by weight of propylene glycol and 18 parts by weight of glycerol (solvent components), and 20 parts by weight of metformin hydrochloride (functional component) were weighed and mixed evenly to obtain a composition for preparing the pre-stopper segment. The obtained composition was then extruded to form the pre-stopper segment. The pre-stopper segment prepared above was used to replace the pre-stopper segment in the TEREA model heat-not-burning aerosol generating article in Comparative Example 1 to prepare the aerosol generating article of this application.

[0194] Example 8

[0195] 50 parts by weight of kudzu root powder, 10 parts by weight of gelatin (binder component), 2 parts by weight of propylene glycol and 18 parts by weight of glycerol (solvent components), and 20 parts by weight of metformin hydrochloride (functional component) were weighed and mixed evenly to obtain a composition for preparing the cooling section and support section. The obtained composition was extruded to prepare the cooling section and support section. The cooling section and support section prepared above were used to replace the cooling section and support section in the TEREA model heat-not-burning aerosol generating article in Comparative Example 1 to prepare the aerosol generating article of this application.

[0196] Example 9

[0197] 50 parts by weight of kudzu root powder, 10 parts by weight of gelatin (binder component), 2 parts by weight of propylene glycol and 18 parts by weight of glycerol (solvent components), and 20 parts by weight of metformin hydrochloride (functional component) were weighed and mixed evenly to obtain a composition for preparing a filter section. The obtained composition was then extruded to form a filter section. The filter section prepared above was used to replace the filter section in the TEREA-type heat-not-burn aerosol generating article in Comparative Example 1 to prepare the aerosol generating article of this application.

[0198] Comparative Example 2

[0199] 60 parts by weight of kudzu root powder, 15 parts by weight of gelatin (binder component), 5 parts by weight of propylene glycol and 20 parts by weight of glycerol (solvent components) were weighed and mixed evenly to obtain a composition for preparing the cooling section and support section. The obtained composition was extruded to prepare the cooling section and support section. The cooling section and support section prepared above were used to replace the cooling section and support section in the TEREA model heat-not-burning aerosol generating article in Comparative Example 1 to prepare the aerosol generating article of this application.

[0200] The aerosol-generated products of Examples 7-9 were tested according to the above-described test method for the content of aldehydes and ketones. The test results are shown in Table 4 below.

[0201] Table 4

[0202]

[0203] As can be seen from the above results, compared with Comparative Examples 1 and 2, Examples 7-9, which use the composition of this application to prepare the pre-plug section, support section, cooling section, or filtration section, can reduce the content of aldehydes and ketones in the aerosol-generated products and improve the safety of the aerosol-generated products.

[0204] Example 10

[0205] Replace the filter section of a commercially available traditional cigarette (trade name: Hongtashan, model: Classic 100) with the filter section prepared in Example 9 above.

[0206] Comparative Example 3

[0207] Commercially available traditional cigarettes (product name: Hongtashan, model: Classic 100).

[0208] The aerosol-generated products of Example 10 and Comparative Example 3 were tested according to the above-described test method for the content of aldehydes and ketones. The test results are shown in Table 5 below.

[0209] Table 5

[0210]

[0211]

[0212] As can be seen from the above results, compared with the conventional cigarettes of Comparative Example 3, the cooling section and support section prepared by Example 10 using the composition of this application, or the filter section replacing the corresponding components in conventional cigarettes, can significantly reduce the harmful aldehydes and ketones generated during the inhalation of aerosol-generated products, and can improve the safety of aerosol-generated products.

[0213] The above description is only a preferred embodiment of this application and does not limit the patent scope of this application. All equivalent structural transformations made using the content of this application's specification under the inventive concept of this application, or direct / indirect applications in other related technical fields, are included within the patent protection scope of this application.

Claims

1. A composition for preparing a functional component of an aerosol-generating article, characterized in that, include: Skeletal components; Adhesive components; Solvent components; and Functional components; wherein, the functional components include compounds represented by Formula 1, In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

2. The composition according to claim 1, characterized in that, The functional components include one or more of arginine, metformin hydrochloride, and guanidinoacetic acid.

3. The composition according to claim 1 or 2, characterized in that, The content of the functional component is 0.1%-20% based on the total weight of the composition.

4. The composition according to claim 1 or 2, characterized in that, The skeleton component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components; Preferably, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin; The inorganic chemical raw materials are selected from one or more of the following: metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers. The plant components are selected from one or more of the following: tobacco raw materials, tobacco leaf fragments, tobacco stems, tobacco dust, and aromatic plants; More preferably, the content of the skeleton component is 10%-90% based on the total weight of the composition.

5. The composition according to claim 1 or 2, characterized in that, The adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives; Preferably, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum; The protein-based adhesives include one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant proteins; The polymeric adhesives include one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether; Preferably, the content of the adhesive component is 1%-85% based on the total weight of the composition.

6. The composition according to claim 1 or 2, characterized in that, The solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol; Preferably, the content of the solvent component is 0.1%-40% based on the total weight of the composition.

7. The composition according to claim 1 or 2, characterized in that, The aerosol generating product is selected from combustible aerosol generating products, heated non-combustible aerosol generating products and / or atomized aerosol generating products. Preferably, the functional component is selected from one or more of the functional segment and the matrix segment; More preferably, the functional segment is selected from one or more of the following: the front plug segment, the cooling segment, the support segment, and the filter segment.

8. The composition according to claim 1 or 2, characterized in that, The functional component includes micropores; preferably, the functional component further includes at least one air passage hole, the air passage hole penetrating at least one end of the functional component along its length. Preferably, the functional component is integrally formed by an extrusion process.

9. The use of a functional component to reduce the content of harmful aldehydes and ketones in aerosol-generating products, characterized in that, The functional components include the compounds shown in Formula 1. In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboryl, aromaticboryl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; The substitution refers to the substitution of a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

10. The use according to claim 9, characterized in that, The method of reducing the content of harmful aldehydes and ketones in aerosol-generating products includes applying the functional components to the functional parts of the aerosol-generating products. Preferably, the application of the functional component to the aerosol-generating article includes adding the functional component to the raw material component of the functional component, or spraying or impregnating the functional component with the functional component.

11. A functional component for aerosol generation products, characterized in that, Based on the total weight of the functional components, the functional components include: 4%-98% of the skeletal components; 0.01%-95% adhesive components; Solvent components of 0.01%-50%; and 0.02%-20% of functional components, wherein the functional components include compounds represented by Formula 1. In the formula, R1, R2, and R3 are each independently selected from hydrogen, substituted or unsubstituted C1-C20 alkyl groups, substituted or unsubstituted aromatic groups, substituted or unsubstituted aromatic heterocyclic groups, guanidinyl, hydroxyl, alkoxy, phenolic, mercapto, alkylthio, thiophenolic, mercaptoaromatic, amino, alkylamino, aromatic amino, alkylboronyl, aromaticboronyl, borate, phosphohydrinyl, alkylphosphohydrinyl, aromaticphosphohydrinyl, alkylarsenyl, aromaticarsenyl, alkylsilyl, aromaticsilyl, silicate, alkylselenoyl, aromaticselenoyl, alkyltelluryl, aromatictelluryl, chlorine atom, bromine atom, and iodine atom; the substituted refers to a group selected from the group consisting of alkyl, guanidinyl, hydroxyl, amino, halogen, and aromatic groups.

12. The functional component according to claim 11, characterized in that, The functional components include one or more of arginine, metformin hydrochloride, and guanidinoacetic acid.

13. The functional component according to claim 11 or 12, characterized in that, The skeleton component is selected from one or more of organic chemical raw materials, inorganic chemical raw materials, and plant components; Preferably, the organic chemical raw material is selected from one or more of cellulose, hemicellulose, and lignin; The inorganic chemical raw materials are selected from one or more of the following: metal oxides, CaCO3, SiO2, silicates, borates, carbonates, sulfates, phosphates, activated carbon, and carbon fibers. The plant components are selected from one or more of the following: tobacco raw materials, tobacco leaf fragments, tobacco stems, tobacco dust, and aromatic plants.

14. The functional component according to claim 11 or 12, characterized in that, The adhesive component is selected from one or more of polysaccharide adhesives, protein adhesives, and polymer adhesives; Preferably, the polysaccharide binder includes one or more of carrageenan, xanthan gum, guar gum, agar, sodium carboxymethyl cellulose, sodium alginate, locust bean gum, and konjac gum; The protein-based adhesives include one or more of gelatin, casein, hemoglobin, soy protein, wheat protein, peanut protein, silk protein, and recombinant proteins; The polymeric adhesives include one or more of polyvinyl alcohol, polyacrylic acid, polyacrylate, and polyenol ether.

15. The functional component according to claim 11 or 12, characterized in that, The solvent component is selected from one or more of water, ethanol, propylene glycol, and glycerol.

16. An aerosol-generating product, characterized in that, The aerosol-generating article includes a functional component prepared using the composition according to any one of claims 1-8 or a functional component according to any one of claims 11-15; Preferably, the functional component includes a functional segment and a matrix segment, wherein the functional segment is directly or indirectly adjacent to at least one end of the matrix segment along the axial direction.

17. The aerosol-generating article according to claim 16, characterized in that, The functional component includes micropores; Preferably, the functional component further includes at least one air passage hole, which extends through at least one end of the functional component along its length.

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