An antioxidant composition containing camellia japonica flower extract and a method for preparing the same

Abstract

The application discloses an antioxidant composition containing camellia chrysantha flower extract and a preparation method thereof, and belongs to the technical field of natural plant extract skin care. The antioxidant composition comprises camellia chrysantha flower extract, Astragalus membranaceus root extract, calendula flower extract and fucus extract. The four kinds of natural plant extracts are synergistically combined to form the effect of 'external antioxidant + damage repair', thereby solving the technical problems of single action path, short-acting and inability to repair oxidative damage of traditional single antioxidant component, and effectively improving aging problems such as skin dullness, relaxation and fine lines, and the antioxidant composition has the effects of soothing, anti-inflammation and repairing damaged skin.

Description

Technical Field

[0001] This invention relates to the field of natural plant active ingredient compounding and skin care preparation technology, specifically to an antioxidant composition containing Camellia japonica flower extract and its preparation method. Background Technology

[0002] The core cause of skin aging, dullness, sensitivity, and damage is oxidative stress. Human skin, affected by external and internal factors such as ultraviolet radiation, environmental pollution, irregular sleep patterns, and abnormal free radical metabolism, continuously produces a large number of reactive oxygen species (ROS). Excessive free radicals attack skin cell membranes, collagen, and elastin fibers, damaging the skin barrier structure and leading to a series of skin problems such as dullness, dryness, sagging, fine lines, and sensitivity / redness. Therefore, effectively eliminating free radicals, inhibiting oxidative stress, and repairing oxidative damage are the core directions of anti-aging skincare.

[0003] Currently, most mainstream antioxidant skincare products on the market use single antioxidant ingredients, such as vitamin C, vitamin E, and astaxanthin. These ingredients have obvious technical shortcomings: First, their antioxidant action pathway is singular, only able to eliminate specific types of free radicals and unable to achieve broad-spectrum antioxidant effects; second, they are mostly passive antioxidants, only able to neutralize existing free radicals and unable to activate the skin's own antioxidant mechanisms, resulting in poor antioxidant longevity; third, they only have antioxidant effects and lack skin repair, moisturizing, and soothing effects, unable to repair existing skin damage caused by free radicals, resulting in limited skincare benefits.

[0004] Natural plant extracts have become a research hotspot in the field of antioxidant skincare due to their high safety, diverse activities, and low irritation. Camellia chrysantha, Astragalus membranaceus root, Calendula officinalis, and Ursula vesiculosus are all traditional natural skincare ingredients. Current technologies mostly use them individually or in simple combinations, and there are no reports of precisely proportioning and synergistically combining these four extracts to form a closed-loop antioxidant system. The antioxidant capacity of a single extract is limited, and its mechanism of action is singular, failing to simultaneously address multiple effects such as free radical scavenging, endogenous antioxidant activation, and skin repair, making it difficult to achieve long-lasting and comprehensive antioxidant skincare results. Therefore, this invention combines the differentiated active mechanisms of the four natural extracts, scientifically proportioning and combining them to construct a dual antioxidant protection system, overcoming many shortcomings of existing technologies. Summary of the Invention

[0005] This invention aims to overcome the shortcomings of existing antioxidant products, such as single ingredients, limited effects, lack of repair function, and weak antioxidant durability. It provides an antioxidant composition containing Camellia chrysantha extract and its preparation method. Through the synergistic combination of four natural plant extracts and differentiated antioxidant pathways, it achieves a triple effect of exogenous oxygen scavenging, endogenous defense, and damage repair, significantly improving the broad-spectrum and long-lasting antioxidant properties, while also moisturizing, soothing, and repairing damaged skin.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: In a first aspect, the present invention provides an antioxidant composition containing Camellia chrysantha flower extract, comprising the following raw materials in parts by weight: 5-15 parts Camellia chrysantha flower extract, 7-12 parts Astragalus membranaceus root extract, 3-10 parts Calendula officinalis flower extract, and 4-8 parts Fucus vesiculosus extract.

[0007] Preferably, the antioxidant composition containing Camellia chrysantha flower extract comprises the following raw materials in parts by weight: 8-12 parts Camellia chrysantha flower extract, 9-11 parts Astragalus membranaceus root extract, 5-8 parts Calendula officinalis flower extract, and 5-6 parts Fucus vesiculosus extract.

[0008] Further, preferably, the antioxidant composition containing Camellia chrysantha extract comprises the following raw materials in parts by weight: 9 parts Camellia chrysantha extract, 10 parts Astragalus membranaceus root extract, 6 parts Calendula officinalis flower extract, and 5 parts Fucus vesiculosus extract.

[0009] In a second aspect, the present invention provides a cosmetic comprising an antioxidant composition of the Camellia chrysantha extract described in the first aspect, wherein the content of the antioxidant composition of the Camellia chrysantha extract is 0.1-10 wt%.

[0010] Preferably, the content of the antioxidant composition of the Camellia chrysantha flower extract is 0.5-8 wt%.

[0011] Furthermore, the cosmetic product also contains cosmetically acceptable excipients selected from one or more of moisturizers, emulsifiers, thickeners, antioxidants, pH adjusters, and fragrances.

[0012] Preferably, the cosmetic is an aqueous solution, lotion, cream, gel, serum, or mask.

[0013] Thirdly, the present invention provides the application of the antioxidant composition containing Camellia japonica flower extract described in the first aspect in the preparation of cosmetics, wherein the cosmetics are aqueous solutions, lotions, creams, gels, serums or masks.

[0014] Compared with the prior art, the present invention has the following technical effects: 1. Differentiated and Synergistic Antioxidant System: This invention utilizes four complementary active ingredients with no antagonistic effects, forming a unique dual antioxidant closed loop. Camellia chrysantha flower extract, rich in flavonoids and polyphenols, can quickly remove free radicals from the skin's surface and superficial layers, improving dullness. Calendula officinalis flower extract combines free radical scavenging and anti-inflammatory soothing effects, alleviating skin redness and sensitivity caused by oxidation. Fucus vesiculosus extract contains fucoidan sulfate, which can deeply remove intracellular free radicals, inhibit lipid oxidation, and delay skin aging. This synergistic approach achieves comprehensive exogenous free radical removal, covering different types and levels of oxidation reactions. Astragalus membranaceus root extract, through its flavonoid, saponin, and polysaccharide active ingredients, activates the activity of endogenous antioxidant enzymes in skin cells, enhancing the skin's own antioxidant defense capabilities. This achieves a dual antioxidant mode of "passive oxygen removal + active defense," solving the problems of traditional products' single antioxidant effect and short duration.

[0015] This product combines dual antioxidant and damage repair benefits: Existing antioxidant products can only prevent oxidative damage and cannot repair existing skin problems. The Astragalus membranaceus root extract in this invention possesses excellent moisturizing and skin barrier repair capabilities, and can repair the stratum corneum damaged by free radicals; Calendula officinalis flower extract can soothe skin inflammation, redness, and stinging caused by oxidative stress, and improve the condition of damaged skin; the synergistic effect of multiple ingredients can repair existing oxidative damage while providing antioxidant benefits, achieving a full-chain skincare effect of "defense-antioxidation-repair". Detailed Implementation

[0016] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. The described embodiments are only some preferred embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0017] Unless otherwise specified, the experimental methods used in the embodiments are conventional or common methods in the art, and the materials and reagents used are commercially available unless otherwise specified.

[0018] The raw materials used in the examples and comparative examples are described below: Camellia chrysantha flower extract: purchased from Ximuyuan (Xiamen) Biotechnology Co., Ltd.

[0019] Astragalus membranaceus root extract: purchased from Shaanxi Sain Biotechnology Co., Ltd.

[0020] Calendula flower extract: purchased from Xi'an Lvtian Biotechnology Co., Ltd.

[0021] Fucus vesiculosus extract: purchased from Guangzhou Baiyu Biotechnology Co., Ltd.

[0022] Unless otherwise specified, all components and raw materials used in the embodiments and comparative examples of this invention are commercially available, and the same type of components and raw materials are used in each parallel experiment.

[0023] Example 1 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 9 parts Camellia chrysantha flower extract, 10 parts Astragalus membranaceus root extract, 6 parts Calendula officinalis flower extract, and 5 parts Fucus vesiculosus extract.

[0024] Example 2 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 8 parts Camellia chrysantha flower extract, 11 parts Astragalus membranaceus root extract, 8 parts Calendula officinalis flower extract, and 6 parts Fucus vesiculosus extract.

[0025] Example 3 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratios: 12 parts Camellia chrysantha flower extract, 9 parts Astragalus membranaceus root extract, 5 parts Calendula officinalis flower extract, and 5 parts Fucus vesiculosus extract.

[0026] Example 4 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 5 parts Camellia chrysantha flower extract, 7 parts Astragalus membranaceus root extract, 3 parts Calendula officinalis flower extract, and 4 parts Fucus vesiculosus extract.

[0027] Example 5 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratios: 15 parts Camellia chrysantha flower extract, 12 parts Astragalus membranaceus root extract, 10 parts Calendula officinalis flower extract, and 8 parts Fucus vesiculosus extract.

[0028] Comparative Example 1 An antioxidant composition containing Camellia japonica flower extract, wherein the raw materials are in the following weight ratio: 10 parts Astragalus membranaceus root extract, 6 parts Calendula officinalis flower extract, and 5 parts Fucus vesiculosus extract.

[0029] Comparative Example 2 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 9 parts Camellia chrysantha flower extract, 6 parts Calendula officinalis flower extract, and 5 parts Fucus vesiculosus extract.

[0030] Comparative Example 3 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 9 parts Camellia chrysantha flower extract, 10 parts Astragalus membranaceus root extract, and 5 parts Fucus vesiculosus extract.

[0031] Comparative Example 4 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 9 parts Camellia chrysantha flower extract, 10 parts Astragalus membranaceus root extract, and 6 parts Calendula officinalis flower extract.

[0032] Comparative Example 5 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 2 parts Camellia chrysantha flower extract, 20 parts Astragalus membranaceus root extract, 6 parts Calendula officinalis flower extract, and 1 part Fucus vesiculosus extract.

[0033] Comparative Example 6 An antioxidant composition containing Camellia chrysantha flower extract, wherein the raw materials are in the following weight ratio: 9 parts Camellia chrysantha flower extract, 10 parts Astragalus membranaceus root extract, 1 part Calendula officinalis flower extract, and 15 parts Fucus vesiculosus extract.

[0034] Table 1. Raw material ratios (parts by weight) for the examples and comparative examples Example 1 9 10 6 5 Example 2 8 11 8 6 Example 3 12 9 5 5 Example 4 5 7 3 4 Example 5 15 12 10 8 Comparative Example 1 / 10 6 5 Comparative Example 2 9 / 6 5 Comparative Example 3 9 10 / 5 Comparative Example 4 9 10 6 / Comparative Example 5 2 20 6 1 Comparative Example 6 9 10 1 15 Effect test experiment To verify the antioxidant effect of the composition of the present invention, the DPPH free radical scavenging rate and cellular antioxidant activity were tested on the samples of each embodiment and comparative example. The specific test methods and results are as follows: 1. DPPH free radical scavenging test Principle: DPPH ethanol solution has characteristic absorption at 517 nm. The antioxidant substances in the sample can reduce DPPH free radicals, resulting in a decrease in absorbance. The degree of absorption decrease corresponds to the free radical scavenging ability.

[0035] Preparation of DPPH working solution: Accurately weigh DPPH powder, dissolve it in anhydrous ethanol, and prepare a 0.1 mmol / L DPPH stock solution. Prepare and use immediately in the dark.

[0036] Sample group (A) s ): Take 2.0 mL of the sample solution to be tested, add 2.0 mL of DPPH working solution, vortex mix, react at room temperature in the dark, and detect at 30 min time points.

[0037] Blank control group (A0): Take 2.0 mL of anhydrous ethanol + 2.0 mL of DPPH working solution and incubate under the same conditions in the dark.

[0038] Sample background group (A) b ): Take 2.0 mL of the sample solution to be tested + 2.0 mL of anhydrous ethanol to eliminate the color interference of the sample itself.

[0039] Detection: Ultraviolet A visible spectrophotometer was used to measure absorbance at a wavelength of 517 nm.

[0040] Calculation formula: .

[0041] 2. Cellular antioxidant experiment Plating: HDF (human skin fibroblasts) were seeded into 6-well plates and cultured until the cell confluence reached 70%–80%.

[0042] Drug administration: Discard the old culture medium, add culture medium containing the sample to be tested, and set up a blank control group (only culture medium is added, no sample is added); incubate at 37 ℃ in a 5% CO2 incubator for 24 h.

[0043] Cell collection and lysis: Aspirate the culture medium, wash cells twice with pre-cooled PBS; add cell lysis buffer, lyse on ice, collect the lysis buffer, centrifuge at 4 ℃ and collect the supernatant, which is the intracellular protein sample; protein concentration can be determined simultaneously using the BCA method, and SOD activity is normalized to total protein (U / mg prot).

[0044] SOD detection (according to the kit instructions, WST-1 method) Set up blank wells, control wells, and sample wells; add substrate, enzyme working solution, and supernatant to be tested in sequence; mix well and incubate at 37 ℃. The OD value was read at 450 nm using an ELISA reader; the SOD inhibition rate was calculated, and the total SOD activity (U / mg protein) was obtained.

[0045] SOD activity enhancement rate: .

[0046] Table 2 Summary of Test Results Example 1 82.3 65.2 Example 2 80.1 62.8 Example 3 81.6 63.5 Example 4 75.4 58.7 Example 5 78.2 61.1 Comparative Example 1 45.2 30.5 Comparative Example 2 52.1 38.4 Comparative Example 3 55.3 41.2 Comparative Example 4 48.7 33.6 Comparative Example 5 58.4 43.1 Comparative Example 6 50.6 36.8 Analysis of the test results in Table 2 shows that, in Example 1 of the present invention... 5. The prepared antioxidant composition containing Camellia chrysantha flower extract had a DPPH free radical scavenging rate of 75.4%. The rate of increase in cellular SOD activity was 82.3%, and the rate of increase was 58.7%. The overall antioxidant capacity was 65.2%, demonstrating excellent in vitro antioxidant ability. Example 1 showed the optimal ratio, achieving a DPPH free radical scavenging rate of 82.3% and a cell SOD activity enhancement rate of 65.2%. Example 5 had the highest total amount of each extract, but the antioxidant effect did not increase proportionally with the increase in raw material dosage, indicating that there is an optimal ratio range for each raw material, and that higher active ingredient dosage does not necessarily lead to better antioxidant effects. (Comparative Example 1) 4. It can be seen that when any one of the following components—Camellia chrysantha flower extract, Astragalus membranaceus root extract, Calendula officinalis flower extract, and Fucus vesiculosus extract—is missing from the composition, the DPPH free radical scavenging rate decreases to 45.2%. The rate of increase in cellular SOD activity decreased to 30.5%, while the rate of increase in cellular SOD activity was 55.3%. 41.2% showed a significant decrease in antioxidant performance, with Comparative Example 1, lacking Camellia chrysantha extract, exhibiting the largest decline in antioxidant effect. This demonstrates that Camellia chrysantha extract is the core active ingredient of this composition, and there is a clear synergistic effect among the four extracts. Although Comparative Examples 5 and 6 contained all four extracts, the weight ratios of the components deviated from the limits defined in this invention, resulting in a DPPH free radical scavenging rate of only 50.6%. The increase rate of cellular SOD activity was only 36.8%, while the overall increase rate was 58.4%. The antioxidant effect was 43.1%, significantly worse than that of the embodiments of the present invention, indicating that simply combining four raw materials cannot achieve excellent antioxidant performance, and a specific weight ratio between the components needs to be maintained. Meanwhile, the DPPH free radical scavenging rate and the cell SOD activity enhancement rate of each group of samples showed a positive correlation, indicating that the composition of the present invention can directly scavenge free radicals and enhance intracellular SOD antioxidant enzyme activity, possessing a dual antioxidant mechanism. The two experimental results corroborate each other, proving that the composition within the specified ratio range of the present invention can stably achieve excellent antioxidant effects.

[0047] Application examples The compositions obtained in Examples 1-5 and Comparative Examples 1-6 were respectively prepared into a repair emulsion, and the formulations of the repair emulsions are shown in Table 3.

[0048] Application Example 1 5. Comparison with Example 1 The preparation method of the repair emulsion of grade 6 includes the following steps: S1: Take a portion of the humectant, chelating agent, thickener and deionized water and mix them. Heat the mixture to 70°C and homogenize it at 7000 rpm for 5 minutes. After homogenization, keep it warm for later use to obtain the pre-prepared phase A. S2: Mix the emollient and emulsifier, heat to 75°C, homogenize at 7000 rpm for 5 minutes, keep warm after homogenization, and obtain the pre-prepared phase B; S3: Mix the remaining humectant with the antioxidant and heat to 60°C until completely melted to obtain the pre-formulated C phase; S4: Heat the pre-prepared phase A to 75°C, add the pre-prepared phase B, and homogenize at 7000 rpm for 5 minutes; then cool the system to 50°C, add the pre-prepared phase C while stirring at 500 rpm, and stir until homogeneous; continue cooling to 45°C, add the corresponding example or comparative composition, and continue stirring for 5 minutes; finally, add a pH adjuster to adjust the pH value of the system, stop stirring, and discharge the material to obtain the target repair emulsion.

[0049] Table 3 shows the formulations (by weight %) of the repair emulsions used in Application Examples 1-5 and Comparative Application Examples 1-6.

[0050] Performance verification was performed using test cases 1-5 and comparison application examples 1-6. 1. Human closed patch test The specific test method refers to the "Cosmetic Safety Technical Specifications" (2015 edition), and the human skin patch test is used for testing. The scoring criteria are detailed in Table 4.

[0051] 0 negative reaction 1 The suspected reaction only showed faint erythema. 2 Weak positive reaction (erythema reaction); erythema, infiltration, edema, and papules may be present. 3 Strong positive reaction (herpes reaction); erythema, infiltration, edema, papules, vesicles; the reaction may extend beyond the test area. 4 Extremely strong positive reaction (confluent herpes simplex reaction); obvious erythema, severe infiltration, edema, confluent herpes simplex; reaction extends beyond the test area. Thirty volunteers, aged 23-50, were recruited and signed informed consent forms. Using a suitable patch tester, a closed patch test method was employed. An equal volume of 25 μL of the test substance (measured by pipette) was placed in the patch tester, which was then applied to the volunteer's arm with hypoallergenic adhesive tape. The tape was gently pressed to ensure even application to the skin. The test substance was removed after 24 hours. Skin reactions were observed at 0.5, 24, and 48 hours after patch removal. Adverse skin reactions were recorded and are shown in Table 5.

[0052] Table 5. Results of adverse skin reactions from patch testing.

[0053] Based on the results of the closed patch test in Table 5, 30 healthy volunteers aged 23-50 years were treated with the test products in Examples 1-5 and Comparative Examples 1-6, respectively. Skin reactions were assessed at three observation points: 0.5 h, 24 h, and 48 h after removal of the patch applicator. The results showed that all volunteers had a skin reaction score of 0 at each observation point, with no suspicious or positive reactions of 1 or higher (no skin lesions such as erythema, infiltration, edema, papules, or vesicles were observed). These results indicate that the antioxidant composition containing Camellia japonica flower extract provided by this invention and its comparative formulations did not induce any irritation or sensitization under occlusive skin contact conditions. All tested samples showed negative reactions, confirming its excellent safety and good skin tolerability, fully meeting the safety requirements for topical preparations.

[0054] 2. Skin barrier repair and skin brightening test This test aims to examine the application of Example 1. 5. Comparison and application example 1 6. The actual skincare effects of the obtained emulsion sample in terms of skin barrier repair, soothing redness, and brightening skin tone are investigated through the following experimental procedures.

[0055] Filter 40 Asian female participants aged 60 years or older were included if they simultaneously met the following criteria: a) facial pigmentation or overall dull skin tone; b) evidence of skin barrier impairment, with a transepidermal water loss (TEWL) value ≥ 20 g / (h). m²); c) There is subjective skin sensitivity, which has been confirmed by a professional assessment by a dermatologist; d) There are no major systemic diseases or a history of serious skin diseases.

[0056] Exclusion criteria: Women who are pregnant or breastfeeding; people with severe allergies; and subjects who have participated in other human efficacy evaluation trials within the past 3 months are not eligible for enrollment.

[0057] On the day of the follow-up test, no skincare or makeup products were applied to the subjects' facial areas. After facial cleansing, the subjects sat quietly for 20 minutes in a constant temperature and humidity room with an ambient temperature of 21±1℃ and a relative humidity of 50±10%. The enrolled subjects were randomly divided into 11 experimental groups, with 5 subjects in each group.

[0058] The TewaMeter®™ Hex transdermal moisture loss detection probe and the Colorimeter CL400 colorimetric detection probe from Courage+Khazaka were used to measure the baseline TEWL and ITA° values ​​of the test areas on the left and right sides of the subjects' faces, respectively. The mean of the test results was taken as the initial test data for each group.

[0059] Each group of subjects applied the corresponding test lotion sample to the test area of ​​their face in equal amounts every morning and evening. After using the sample continuously for 28 days, the TEWL and ITA° values ​​of the test area of ​​each group of subjects were measured again, and the mean value of the measurement was taken as the post-use test data.

[0060] Based on the average values ​​before and after testing, the improvement rate of each indicator was calculated using the following formula: TEWL Improvement Rate (%) = (Initial TEWL) TEWL after use ÷ Initial TEWL × 100%; ITA° Improvement Rate (%) = (ITA° after use) (Initial ITA°) ÷ Initial ITA° × 100%.

[0061] The evaluation logic for the above indicators is as follows: the higher the TEWL improvement rate, the more outstanding the repair effect of the sample on the damaged skin barrier; the higher the ITA° improvement rate, the better the whitening effect of the sample in brightening skin tone and improving dullness. The experimental results are shown in Table 6.

[0062] Table 6 Results of Skin Barrier Repair and Skin Brightening Trials Application Example 1 34.7 22.6 Application Example 2 32.5 21.3 Application Example 3 33.2 21.8 Application Example 4 28.9 18.5 Application Example 5 29.6 19.2 Comparative Application Example 1 14.3 8.7 Comparative Application Example 2 17.1 10.4 Comparative Application Example 3 18.6 11.5 Comparative Application Example 4 15.8 9.3 Comparative Application Example 5 20.2 12.7 Comparative Application Example 6 16.5 10.1 According to the data in Table 6, 1) Application Example 1 5. Containing four active ingredients—Camellia chrysantha flower extract, Astragalus membranaceus root extract, Calendula officinalis flower extract, and Fucus vesiculosus extract—TEWL achieves an improvement rate of 28.9%. 34.7%, ITA° improvement rate is 18.5%. 22.6%. Application Example 1 showed the best overall performance, with a TEWL improvement rate of 34.7% and an ITA° improvement rate of 22.6%, consistent with the trends observed in in vitro DPPH free radical scavenging rate and cell SOD activity enhancement rate. 2) Application Example 4 had a relatively low overall level of active ingredients, resulting in the lowest in vitro antioxidant index. Correspondingly, the improvement effects on human TEWL and ITA° were also the lowest within the example group. Application Example 5 had the highest dosage of each extract, but the efficacy did not increase linearly and significantly with the amount of raw materials used. This indicates that there is an optimal ratio range for the four extracts, and higher dosages do not necessarily lead to better results; excessively high doses did not bring a proportional increase in efficacy. 3) Comparing Application Examples 1-4, removing one active ingredient from each of the following: Camellia chrysantha flower extract, Astragalus membranaceus root extract, Calendula officinalis flower extract, and Fucus vesiculosus extract, resulted in a TEWL improvement rate of only 14.3%-18.6% and an ITA° improvement rate of 8.7%-11.5%. This is a significant decrease compared to Application Example 1 with the complete formula, indicating that the four extracts do not simply add up but have a synergistic effect. The absence of any one active ingredient significantly reduces the skin barrier repair and skin brightening capabilities of the composition. 4) Comparing Application Example 5, the amount of Camellia chrysantha flower extract was too low, the amount of Astragalus membranaceus root extract was too high, and the amount of Fucus vesiculosus extract was too low; comparing Application Example 6, the amount of Calendula officinalis flower extract was extremely low, and the amount of Fucus vesiculosus extract was too high. Although all four active substances were retained in both groups, the component weight ratios deviated from the scope of this invention. The TEWL improvement rates were 20.2% and 16.5%, and the ITA° improvement rates were 12.7% and 10.1%, respectively, significantly lower than Application Example 1. 5. This result indicates that the proper ratio of the four extracts is key to achieving the effects of barrier repair and brightening.

[0063] The preferred embodiments of the present invention disclosed above are merely illustrative of the invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the invention to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of the invention, thereby enabling those skilled in the art to better understand and utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. An antioxidant composition containing Camellia chrysantha flower extract, characterized in that, It is composed of the following natural plant extracts in parts by weight: 5-15 parts Camellia japonica flower extract, 7-12 parts Astragalus membranaceus root extract, 3-10 parts Calendula officinalis flower extract, and 4-8 parts Fucus vesiculosus extract.

2. The antioxidant composition containing Camellia chrysantha flower extract according to claim 1, characterized in that, It is composed of the following raw materials in parts by weight: 8-12 parts of Camellia chrysantha flower extract, 9-11 parts of Astragalus membranaceus root extract, 5-8 parts of Calendula officinalis flower extract, and 5-6 parts of Fucus vesiculosus extract.

3. A cosmetic product, characterized in that, It comprises an antioxidant composition of the Camellia chrysantha flower extract as described in claim 1 or 2, wherein the content of the antioxidant composition of the Camellia chrysantha flower extract is 0.1-10 wt%.

4. The cosmetic product according to claim 3, characterized in that, The content of the antioxidant composition of the Camellia chrysantha flower extract is 0.5-8 wt%.

5. The cosmetic product according to claim 3, characterized in that, The cosmetics also contain cosmetically acceptable excipients.

6. The cosmetic product according to claim 5, characterized in that, The excipients are selected from one or more of the following: humectants, emulsifiers, thickeners, antioxidants, pH adjusters, and fragrances.

7. The cosmetic product according to claim 3, characterized in that, The cosmetics are aqueous solutions, lotions, creams, gels, serums, or masks.

8. The use of the antioxidant composition according to any one of claims 1-2 in the preparation of cosmetics, characterized in that, The cosmetic is selected from at least one of aqueous solution, lotion, cream, gel, serum or mask.

9. The application according to claim 8, characterized in that, The content of the antioxidant composition of the Camellia chrysantha flower extract is 0.1-10 wt%.

10. The application according to claim 9, characterized in that, The content of the antioxidant composition of the Camellia chrysantha flower extract is 0.5-8 wt%.

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