A traditional Chinese medicine formula, preparation method and use

Abstract

The application provides a traditional Chinese medicine formula, a preparation method and an application. The formula comprises 9-11 parts of Caesalpinia sappan, 32-35 parts of Sambucus williamsii, 9-11 parts of Panax notoginseng, 9-11 parts of Redbud bark, 19-21 parts of North liverwort, 9-11 parts of Rhizoma et Radix Ligustici Wallichii, 12-15 parts of Radix et Rhizoma Corydalis, 12-15 parts of Radix Paeoniae Rubra, 15-18 parts of Angelica sinensis, 9-11 parts of Herba Lycopodii, 19-21 parts of Herba Altemantherae and 9-11 parts of Radix et Rhizoma Rhei. The traditional Chinese medicine formula can play the roles of activating blood circulation to dissipate blood stasis, promoting qi to relieve pain, removing stasis and resolving masses, dredging collaterals and connecting tendons and bones, and can comprehensively regulate the pain, swelling, ecchymosis, tenderness and limited activity caused by qi stagnation and blood stasis after fracture. The preparation process is beneficial to the extraction and dispersion of effective components, the obtained granules are stable in composition, accurate in dosage and convenient to take. The granules can be used for patients with qi stagnation and blood stasis syndrome caused by tibial and fibular fracture, distal radius fracture, tibial plateau fracture, ankle fracture and rib fracture, and can relieve pain.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine formulation technology, and in particular to a traditional Chinese medicine formulation, preparation method, and uses. Background Technology

[0002] Fractures are common orthopedic diseases, mostly caused by falls, traffic accidents, sports injuries, and other external forces. Common types include tibia and fibula fractures, distal radius fractures, tibial plateau fractures, ankle fractures, and rib fractures. After a fracture, local tissues and blood vessels are damaged, and patients usually experience symptoms such as pain, swelling, bruising, tenderness, and limited mobility. Some patients may also have significant deformities, which greatly affect their daily activities and quality of life. Traditional Chinese medicine considers fractures to fall under the categories of "fracture" and "muscle / tendon injury." External force injuries can lead to damage to tendons and bones, damage to blood vessels, and obstruction of qi and blood circulation, resulting in blood stasis in the meridians, thus forming a pathological state of "pain due to obstruction." In the early stages of a fracture, it often manifests as qi stagnation and blood stasis syndrome, with symptoms such as local stabbing pain, fixed pain location, swelling and bruising, as well as a dark or purplish tongue and a wiry and hesitant pulse. Therefore, in addition to routine reduction, fixation and necessary surgical treatment of fractures, how to use traditional Chinese medicine to promote blood circulation, remove blood stasis, reduce swelling and relieve pain, regulate qi and unblock collaterals, and promote tendon and bone regeneration, so as to improve clinical symptoms such as pain, swelling and limited mobility after fracture, has always been an important research direction in the field of traditional Chinese medicine orthopedics.

[0003] Currently, there are many types of traditional Chinese medicine (TCM) preparations used clinically as adjunctive treatments for fractures and sprains. Their prescriptions typically consist of drugs that promote blood circulation, remove blood stasis, regulate qi, relieve pain, and strengthen tendons and bones. However, there are significant differences in the efficacy emphasis, proportions, and preparation processes among different drugs. Some traditional prescriptions suffer from problems such as uncoordinated drug combinations, insufficient extraction of active ingredients, lack of standardized dosage ranges, and inconvenience in administration and portability. These limitations make it difficult to address the multifaceted treatment needs of early fracture treatment, including blood stasis, pain, swelling, and subsequent bone and tendon repair. Especially for patients with fractures caused by qi stagnation and blood stasis, there is a need for a TCM composition with a reasonable combination, relatively stable composition, and the ability to promote blood circulation, remove blood stasis, regulate qi, relieve pain, reduce swelling, and strengthen tendons and bones. Furthermore, appropriate extraction, concentration, and granulation processes should be used to improve the stability and ease of administration of the preparation. Therefore, it is necessary to scientifically combine multiple Chinese herbs with the functions of promoting blood circulation, removing blood stasis, relieving pain, and promoting tendon and bone healing, based on the traditional Chinese medicine theory of bone injury, and to establish relatively standardized preparation methods, so as to provide a new Chinese medicine treatment or adjuvant treatment plan for fracture patients, especially those with qi stagnation and blood stasis syndrome. Summary of the Invention

[0004] This invention aims to at least solve the technical problems existing in the prior art, and in particular, innovatively proposes a traditional Chinese medicine formula, preparation method and use.

[0005] To achieve the above-mentioned objectives of the present invention, the present invention provides a traditional Chinese medicine formula, which includes: 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of Corydalis yanhusuo (processed with vinegar), 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of Drynaria fortunei (processed with hot water), 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of Rheum palmatum (processed with wine).

[0006] As an optional embodiment of the present invention, the following ingredients may be used: 10 to 11 parts of Sappanwood, 33.3 to 35 parts of Elderberry, 10 to 11 parts of Panax notoginseng, 10 to 11 parts of Bauhinia bark, 20 to 21 parts of Artemisia capillaris, 10 to 11 parts of Ligusticum chuanxiong, 13.3 to 15 parts of vinegar-processed Corydalis yanhusuo, 13.3 to 15 parts of Paeonia lactiflora, 16.7 to 18 parts of Angelica sinensis, 10 to 11 parts of Drynaria fortunei, 20 to 21 parts of Shenqu (medicated leaven), and 10 to 11 parts of wine-processed Rhubarb.

[0007] As an optional embodiment of the present invention, the following ingredients may be used: 9 to 10 parts of Sappanwood, 32 to 33.3 parts of Elderberry, 9 to 10 parts of Panax notoginseng, 9 to 10 parts of Bauhinia bark, 19 to 20 parts of Artemisia capillaris, 9 to 10 parts of Ligusticum chuanxiong, 12 to 13.3 parts of vinegar-processed Corydalis yanhusuo, 12 to 13.3 parts of Paeonia lactiflora, 15 to 16.7 parts of Angelica sinensis, 9 to 10 parts of Drynaria fortunei, 19 to 20 parts of Shenqu (medicated leaven), and 9 to 10 parts of wine-processed Rhubarb.

[0008] On the other hand, the present invention also provides a method for preparing a traditional Chinese medicine formula, comprising taking 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of vinegar-processed Corydalis yanhusuo, 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of dried Drynaria fortunei, 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of wine-processed Rhubarb, and adding six times the amount of water to soak for 0.5 hours, decocting three times, each time for 45 minutes, filtering the decoction from the three decoctions, combining the filtered filtrates, and concentrating them into an extract with a relative density of 1.15 to 1.25, drying and pulverizing it into a dry extract powder, adding 5 to 15 parts of starch to the extract powder, mixing well, and using 75% to 80% ethanol as a hydrating agent to prepare granules.

[0009] On the other hand, the present invention also provides a traditional Chinese medicine formula for the treatment of fractures.

[0010] The beneficial effects of this invention are as follows: The traditional Chinese medicine formula provided by this invention combines Sappanwood, Elderberry, Panax notoginseng, Bauhinia bark, Artemisia capillaris, Ligusticum chuanxiong, vinegar-processed Corydalis yanhusuo, Paeonia lactiflora, Angelica sinensis, dried Drynaria fortunei, Shenqu (medicated leaven), and wine-processed Rhubarb. These herbs work synergistically to promote blood circulation, remove blood stasis, regulate qi, relieve pain, reduce swelling and dissipate nodules, unblock meridians and tendons, and strengthen tendons and bones. It can comprehensively regulate symptoms such as local pain, swelling, bruising, tenderness, and limited mobility caused by qi stagnation and blood stasis after fracture. Compared to treatments with relatively singular effects, it can simultaneously address the improvement of early-stage blood stasis and the recovery of damaged tissues and bone function. Furthermore, by rationally limiting the proportions of each raw material and employing a preparation process involving water soaking, multiple decoctions, filtration, concentration, drying, and granulation, this invention facilitates the full extraction and uniform dispersion of the effective components of the traditional Chinese medicine, resulting in granules with stable composition, relatively accurate dosage, and convenient administration and portability. Clinical application results show that the traditional Chinese medicine formula of this invention, when used for patients with qi stagnation and blood stasis syndrome such as tibial and fibular fractures, distal radius fractures, tibial plateau fractures, ankle fractures, and rib fractures, can reduce pain, tenderness, and local swelling at the fracture site within a short treatment cycle, and improve the limitation of movement at the affected area. Therefore, it has good application value in the adjuvant treatment of fractures.

[0011] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Detailed Implementation

[0012] The embodiments of the present invention are described in detail below, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The following embodiments are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0013] Example 1 A traditional Chinese medicine formula comprising: 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of Corydalis yanhusuo (processed with vinegar), 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of Drynaria fortunei (processed with hot water), 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of Rheum palmatum (processed with wine).

[0014] Example 2 As an optional embodiment of the present invention, the following ingredients may be used: 10 to 11 parts of Sappanwood, 33.3 to 35 parts of Elderberry, 10 to 11 parts of Panax notoginseng, 10 to 11 parts of Bauhinia bark, 20 to 21 parts of Artemisia capillaris, 10 to 11 parts of Ligusticum chuanxiong, 13.3 to 15 parts of vinegar-processed Corydalis yanhusuo, 13.3 to 15 parts of Paeonia lactiflora, 16.7 to 18 parts of Angelica sinensis, 10 to 11 parts of Drynaria fortunei, 20 to 21 parts of Shenqu (medicated leaven), and 10 to 11 parts of wine-processed Rhubarb.

[0015] Example 3 As an optional embodiment of the present invention, the following ingredients may be used: 9 to 10 parts of Sappanwood, 32 to 33.3 parts of Elderberry, 9 to 10 parts of Panax notoginseng, 9 to 10 parts of Bauhinia bark, 19 to 20 parts of Artemisia capillaris, 9 to 10 parts of Ligusticum chuanxiong, 12 to 13.3 parts of vinegar-processed Corydalis yanhusuo, 12 to 13.3 parts of Paeonia lactiflora, 15 to 16.7 parts of Angelica sinensis, 9 to 10 parts of Drynaria fortunei, 19 to 20 parts of Shenqu (medicated leaven), and 9 to 10 parts of wine-processed Rhubarb.

[0016] Example 4 As an optional embodiment of the present invention, optionally, 9 parts of Sappanwood, 32 parts of Elderberry, 9 parts of Panax notoginseng, 9 parts of Bauhinia bark, 19 parts of Artemisia capillaris, 9 parts of Ligusticum chuanxiong, 12 parts of vinegar-processed Corydalis yanhusuo, 12 parts of Paeonia lactiflora, 15 parts of Angelica sinensis, 9 parts of dried bone-setting Drynaria fortunei, 19 parts of Shenqu (medicated leaven), and 9 parts of wine-processed Rhubarb are processed according to the preparation method described above to finally obtain a stable finished product of traditional Chinese medicine granules.

[0017] Example 5 As an optional embodiment of the present invention, optionally, 10 parts of Sappanwood, 33.3 parts of Elderberry, 10 parts of Panax notoginseng, 10 parts of Bauhinia bark, 20 parts of Artemisia capillaris, 10 parts of Ligusticum chuanxiong, 13.3 parts of vinegar-processed Corydalis yanhusuo, 13.3 parts of Paeonia lactiflora, 16.7 parts of Angelica sinensis, 10 parts of Drynaria fortunei, 20 parts of Shenqu (medicated leaven), and 10 parts of wine-processed Rhubarb are processed according to the preparation method described above to finally obtain a stable finished product of traditional Chinese medicine granules.

[0018] Example 6 As an optional embodiment of the present invention, optionally, 11 parts of Sappanwood, 35 parts of Elderberry, 11 parts of Panax notoginseng, 11 parts of Bauhinia bark, 21 parts of Artemisia capillaris, 11 parts of Ligusticum chuanxiong, 15 parts of vinegar-processed Corydalis yanhusuo, 15 parts of Paeonia lactiflora, 18 parts of Angelica sinensis, 11 parts of dried bone-setting Drynaria fortunei, 21 parts of Shenqu (medicated leaven), and 11 parts of wine-processed Rhubarb are processed according to the preparation method described in claim 4 to finally obtain a stable finished product of traditional Chinese medicine granules.

[0019] Example 7 As an optional embodiment of the present invention, optionally, 10 parts of Sappanwood, 34 parts of Elderberry, 10 parts of Panax notoginseng, 10 parts of Bauhinia bark, 20 parts of Artemisia capillaris, 10 parts of Ligusticum chuanxiong, 14 parts of vinegar-processed Corydalis yanhusuo, 14 parts of Paeonia lactiflora, 17 parts of Angelica sinensis, 10 parts of dried bone-setting Drynaria fortunei, 20 parts of Shenqu (medicated leaven), and 10 parts of wine-processed Rhubarb are processed according to the preparation method described above to finally obtain a stable finished product of traditional Chinese medicine granules.

[0020] Example 8 A method for preparing a traditional Chinese medicine formula involves taking 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of vinegar-processed Corydalis yanhusuo, 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of dried Drynaria fortunei, 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of wine-processed Rhubarb. The ingredients are then soaked in six times the amount of water for 0.5 hours, decocted three times for 45 minutes each time, and the decoctions from the three decoctions are filtered. The filtrates are combined and concentrated into an extract with a relative density of 1.15 to 1.25. After drying, the extract is pulverized into a dry extract powder. 5 to 15 parts of starch are added to the extract powder and mixed well. 75% to 80% ethanol is used as a hydrating agent to prepare granules.

[0021] The three-stage decoction process used in this method is designed specifically for the characteristics of the multiple herbal ingredients in this formula. It allows for the gradual and thorough extraction of various effective components, avoiding waste and ensuring both extraction efficiency and purity. Secondly, the relative density of the concentrated extract is controlled within the range of 1.15 to 1.25, an optimal parameter obtained through multiple rounds of process optimization. This density range avoids excessive viscosity, which would increase the difficulty of subsequent drying, pulverizing, and granulation processes, while also preventing excessively low density from leading to high energy consumption and prolonged production cycles during concentration, effectively improving the overall production efficiency of the preparation process. Furthermore, using 75% to 80% ethanol as a wetting agent for granulation results in granules with good formability, uniform particle size, and excellent solubility, meeting the clinical need for direct administration with warm water and suitable for various usage scenarios such as outpatient clinics and home use. All raw materials used in this preparation method are cleaned and qualified Chinese medicinal herbs, and all production processes comply with the requirements of the Good Manufacturing Practice (GMP) for Chinese medicine preparations. The resulting product has stable and controllable quality, making it suitable for large-scale industrial production.

[0022] Example 9 A traditional Chinese medicine formula, the application of which in the treatment of fractures.

[0023] Case 1: Mr. Dai, male, 64 years old, presented in July 2022 with a 3-hour history of swelling, pain, and limited mobility in his left lower leg due to trauma. Presenting symptoms: Upon entering the ward in a wheelchair, the patient was conscious and in good spirits. He complained of pain and discomfort in his left lower leg, with limited mobility and increased pain upon movement. A mild anterolateral angulation was observed in the lower middle segment of the lower leg. Appetite, sleep, and bowel movements were normal. Physical examination revealed anterolateral angulation in the lower middle segment of the left lower leg, external rotation deformity of the foot, no skin ulceration, significant tenderness and percussion pain in the lower middle and proximal lateral segments of the left lower leg, and longitudinal percussion pain in the left lower extremity. Obvious crepitus was palpable locally. The dorsalis pedis artery pulsation was present, and the movement of all toes was normal, with normal peripheral blood circulation. The tongue was pale with a thin white coating, and the pulse was wiry and hesitant. Traditional Chinese Medicine diagnosis: Tibial and fibular fracture (Qi stagnation and blood stasis syndrome). Western medicine diagnosis: Left tibia and fibular fracture. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 10 days of treatment, the pain in the left calf was significantly reduced, mobility improved, local tenderness and swelling in the left calf decreased.

[0024] Case 2: Patient Ren, female, 64 years old. She presented in August 2023 with "swelling, pain, deformity, and limited movement of the right wrist due to trauma for 4 days." She experienced sharp, fixed pain in her right wrist, with limited wrist joint movement. Physical examination revealed swelling and ulnar deviation of the right wrist and dorsum of the hand; the local skin was intact without ulceration. Significant tenderness was present in the right wrist, with palpable crepitus and pulsation. Rotation of the right forearm and wrist joint movement were limited; finger movement was normal. Numbness was present on the palmar side of the 3rd and 4th fingers of the right hand. Sensation and blood circulation in the remaining fingertips were normal. Muscle strength and tone in all four limbs were normal. Neurological examination showed physiological reflexes present, but pathological reflexes were not elicited. Her tongue was pale with a thin white coating, and her pulse was wiry and hesitant. Traditional Chinese Medicine diagnosis: Distal radius fracture of the right hand (Qi stagnation and blood stasis syndrome). Western medicine diagnosis: Distal radius fracture of the right hand. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 10 days of treatment, the pain in the right wrist was significantly reduced, mobility improved, local tenderness and swelling in the right wrist decreased.

[0025] Case 3: Patient Liu, male, 39 years old. He presented in February 2023 with "swelling, pain, deformity, and limited mobility in the right wrist due to trauma for 4 days." He experienced stabbing pain in his right knee and chest, the pain was fixed and did not shift, knee joint movement was limited, and chest pain was significantly aggravated by coughing. Physical examination: The spine was straight without deformity, no obvious deformities were found in the limbs, the skin of the right knee was intact without ulceration or subcutaneous ecchymosis, and the local skin color and temperature were normal. The right knee joint was slightly swollen and painful, with limited flexion movement; the pain worsened with flexion and was relieved by extension. The medial and lateral stress tests of the right knee joint were negative, as were the patellar grinding test and the anterior and posterior drawer tests. Muscle strength and tone in all four limbs were normal, the dorsalis pedis artery pulse was present on the right side, the movement of all toes in the right foot was normal, and peripheral blood circulation in the right foot was normal. His tongue was pale with a thin white coating, and his pulse was wiry and hesitant. Traditional Chinese Medicine Diagnosis: Right tibial fracture (Qi stagnation and blood stasis syndrome). Western Medicine Diagnosis: 1. Right tibial plateau fracture; 2. Right tibial intercondylar spine fracture; 3. Right 5th rib fracture. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 5 days of treatment, the pain in the right knee and chest was significantly reduced, and mobility improved. Local tenderness and swelling in the right calf and chest were significantly reduced, and knee joint mobility improved.

[0026] Case 4: Patient Wu, female, 81 years old. She presented in June 2024 with "swelling and pain in the right ankle with limited mobility for one day due to trauma." She was admitted in a wheelchair. The patient was conscious and in good spirits. She complained of sharp, fixed pain in her right ankle, limited lower leg movement, and increased pain with activity. Sleep and bowel movements were normal. Physical examination revealed swelling of the right lower leg, ankle, and dorsum of the foot; bruising on the lower leg and dorsum of the foot; no skin ulceration; significant tenderness and percussion pain around the right ankle joint; longitudinal percussion pain in the right lower extremity. Crepitus was palpable and audible in the ankle; dorsalis pedis artery pulsation was present; movement of all toes was normal; peripheral blood circulation was normal. Her tongue was pale with a thin white coating; and her pulse was wiry and hesitant. Traditional Chinese Medicine diagnosis: Right ankle fracture (Qi stagnation and blood stasis syndrome). Western medicine diagnosis: Right trimalleolar fracture. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 7 days of treatment, the pain in the right ankle was significantly reduced, mobility improved, local tenderness in the right ankle decreased, and bruising and swelling lessened.

[0027] Case 5: Patient Tian, ​​female, 55 years old. She presented in April 2025 with a 4-day history of "swelling, pain, deformity, and limited movement in the right wrist due to trauma." Her right wrist was painful, described as stabbing, and the pain was fixed in one location. Wrist joint movement was limited. Physical examination revealed a "pistol-like" deformity in the right wrist with slight swelling; tenderness, palpable crepitus, and audible crepitus; abduction, flexion, elevation, and extension of the right upper limb were normal, but flexion, extension, pronation, and supination of the right wrist joint were limited, and finger flexion and extension were slightly limited. Sensation and blood circulation in the extremities were normal. Her tongue was purplish-dark with a thin white coating, and her pulse was wiry and hesitant. Traditional Chinese Medicine diagnosis: Distal radius fracture of the right wrist (Qi stagnation and blood stasis syndrome). Western medicine diagnosis: Distal radius fracture of the right wrist. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 10 days of treatment, the pain in the right wrist significantly decreased, movement improved, local tenderness and swelling decreased.

[0028] Case 6: Mr. Li, male, 56 years old, presented in August 2026 with "right chest pain for 1 day due to trauma." The patient experienced stabbing pain in his right chest, which was fixed and did not shift. There was slight swelling of the soft tissue in the right chest, but no obvious redness or skin lesions. There was tenderness upon palpation near the middle and posterior segment of the right 11th rib, with significant pain. The chest compression test was positive. He occasionally coughed, and his chest breathing was slightly restricted; deep breathing and coughing caused local pain. No obvious bone crepitus was palpable or audible. Breathing was normal; auscultation of the lungs revealed a few moist rales, and the breath sounds were slightly coarse. His tongue was pale with a thin white coating, and his pulse was wiry and hesitant. Traditional Chinese Medicine diagnosis: Rib fracture (Qi stagnation and blood stasis syndrome). Western medicine diagnosis: Right 11th rib fracture. Treatment: Suhuang Shangtongding granules, one packet three times a day. After 5 days of treatment, the chest pain significantly decreased, and the local tenderness in the right chest disappeared.

[0029] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A traditional Chinese medicine formula, characterized in that, The formula includes: 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of Corydalis yanhusuo (processed with vinegar), 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of Drynaria fortunei (processed with hot water), 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of Rheum palmatum (processed with wine).

2. The traditional Chinese medicine formula as described in claim 1, characterized in that, Sappanwood 10 to 11 parts, elderberry 33.3 to 35 parts, Panax notoginseng 10 to 11 parts, Bauhinia bark 10 to 11 parts, Artemisia capillaris 20 to 21 parts, Ligusticum chuanxiong 10 to 11 parts, vinegar-processed Corydalis yanhusuo 13.3 to 15 parts, Paeonia lactiflora 13.3 to 15 parts, Angelica sinensis 16.7 to 18 parts, Drynaria fortunei 10 to 11 parts, Shenqu 20 to 21 parts, and wine-processed rhubarb 10 to 11 parts.

3. A traditional Chinese medicine formula as described in claim 2, characterized in that, Sappanwood 9 to 10 parts, elderberry 32 to 33.3 parts, Panax notoginseng 9 to 10 parts, Bauhinia bark 9 to 10 parts, Artemisia capillaris 19 to 20 parts, Ligusticum chuanxiong 9 to 10 parts, vinegar-processed Corydalis yanhusuo 12 to 13.3 parts, Paeonia lactiflora 12 to 13.3 parts, Angelica sinensis 15 to 16.7 parts, dried bone-setting herb 9 to 10 parts, Shenqu 19 to 20 parts, and wine-processed rhubarb 9 to 10 parts.

4. A method for preparing a traditional Chinese medicine formula as described in any one of claims 1 to 3, characterized in that, Take 9 to 11 parts of Sappanwood, 32 to 35 parts of Elderberry, 9 to 11 parts of Panax notoginseng, 9 to 11 parts of Bauhinia bark, 19 to 21 parts of Artemisia capillaris, 9 to 11 parts of Ligusticum chuanxiong, 12 to 15 parts of vinegar-processed Corydalis yanhusuo, 12 to 15 parts of Paeonia lactiflora, 15 to 18 parts of Angelica sinensis, 9 to 11 parts of dried Drynaria fortunei, 19 to 21 parts of Shenqu (medicated leaven), and 9 to 11 parts of wine-processed Rheum palmatum. Add six times the amount of water and soak for 0.5 hours. Decoction three times, 45 minutes each time. Filter the decoctions from the three decoctions. Combine the filtered liquids and concentrate them into an extract with a relative density of 1.15 to 1.

25. Dry the extract and pulverize it into a dry extract powder. Add 5 to 15 parts of starch to the extract powder, mix well, and use 75% to 80% ethanol as a humectant to make granules.

5. A traditional Chinese medicine formula as described in any one of claims 1 to 3, characterized in that, The application of the traditional Chinese medicine formula in the treatment of fractures.