Pharmacokinetic test waste liquid and waste sample centralized collection device

Abstract

The present application relates to a kind of pharmacokinetic test waste liquid and waste sample centralized collection device, comprising: main component, it includes five containing components fixed in the middle of the main component, support component sliding in the bottom of the containing component, adaptive component and fixed component sliding in the inside of the containing component, the adaptive component and fixed component are connected, track component sliding in the inside of the adaptive component corresponding the center of main component, elastic component fixed in the inner wall of the track component, the elastic component and main component are connected.The present application is through containing component, support component, adaptive component, track component, fixed component, elastic component, adjusting component and its subsequent structure cooperation, realizes the adaptive positioning and fixed effect of multiple specifications test tube, also can be adjusted to adapt multiple height test tube, and it is more convenient when taking and placing.

Description

Technical Field

[0001] This invention relates to the field of pharmacokinetic research technology, and in particular to a device for the centralized collection of waste liquid and discarded samples from pharmacokinetic experiments. Background Technology

[0002] The centralized collection device for waste liquids and waste samples from pharmacokinetic experiments is a sealed temporary storage device for complex waste liquids and biological waste samples generated throughout the entire process of pharmacokinetic research. It avoids risks such as biological pollution, chemical corrosion, and diffusion of volatile organic compounds, meets the requirements for hazardous waste management, ensures the safety of researchers and the surrounding environment, and helps to carry out pharmacokinetic experiments efficiently and in a standardized manner.

[0003] The conventional procedure for handling waste liquids and discarded biological samples generated from pharmacokinetic experiments is to first seal them in special test tubes for temporary storage, and then transport them to a designated area for centralized collection. However, the collection devices currently available on the market generally have insufficient structural adaptability when handling these test tube containers internally or across workstations. The containers are prone to shaking and displacement during the transfer process, and there are even problems such as loosening of the tube caps and leakage. These issues make it difficult to meet the biosafety and hazardous waste management requirements in experimental scenarios, and therefore improvements are needed. Summary of the Invention

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be construed as limiting the scope of the invention.

[0005] To solve the above-mentioned technical problems, the present invention provides the following technical solution: a device for centralized collection of waste liquid and waste samples from pharmacokinetic experiments, comprising: a main body assembly, which includes five receiving components fixed in the middle of the main body assembly, a support component sliding at the bottom of the receiving components, an adapter component and a fixing component sliding inside the receiving components, the adapter component and the fixing component being connected, a track component sliding inside the adapter component corresponding to the center of the main body assembly, an elastic component fixed to the inner wall of the track component, the elastic component being connected to the main body assembly, a conduction component fixed inside the main body assembly corresponding to the receiving components and the support component, and an adjustment component sliding at the bottom of the main body assembly, the adjustment component and the conduction component being connected.

[0006] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample centralized collection device of the present invention, the main component includes a collection box, a pentagonal ring fixed inside the collection box, the five sides of the pentagonal ring are provided with reserved grooves, and a central tube at the top of the pentagonal ring is fixed.

[0007] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the receiving component includes a receiving shell fixed in the reserved groove, a first sliding groove is provided on the inner side of the receiving shell, a second sliding groove is provided on the inner side of the receiving shell corresponding to the top of the first sliding groove, a hollow rubber block is fixed at the opening of the receiving shell, and a first conical groove is provided at the end of the hollow rubber block.

[0008] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the supporting component includes an expansion shell that slides at the bottom of the receiving shell, a soft block fixed at the opening of the expansion shell corresponding to the bottom of the hollow rubber block, the soft block having a second conical groove at the bottom of the first conical groove, and the soft block having an inclined surface inside the second conical groove.

[0009] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the adapter component includes a squeezing plate that slides in the first chute and a driven rod fixed to the top of the squeezing plate.

[0010] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the track assembly includes a disc located at the top of the extrusion plate corresponding to the center of the collection box, and the end face of the disc is provided with an arc-shaped groove corresponding to the driven rod.

[0011] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the fixing component includes a slide plate that slides in the second slide groove, the bottom of the slide plate and the top of the driven rod are fixedly connected, and a rubber roller that rotates at the outer end of the slide plate has the same diameter as the thickness of the slide plate.

[0012] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the elastic component includes a protruding tube fixed to the inner wall of the disc, the inner wall of the protruding tube and the outer wall of the central tube being rotatably connected, a connecting block fixed to the inner wall of the protruding end of the top of the protruding tube, a tension spring fixed to the end face of the connecting block, and a driven block fixed to the end of the tension spring, the inner side of the driven block being fixedly connected to the outer wall of the central tube.

[0013] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the conductive component includes a receiving tank fixed to the inner wall of the central tube, a heat-conducting plate fixed to the outer wall of the receiving tank corresponding to the bottom of the receiving component, and a multi-ring component fixed to the end of the heat-conducting plate.

[0014] As a preferred embodiment of the pharmacokinetic test waste liquid and waste sample collection device of the present invention, the adjustment component includes a bottom support plate that slides on the bottom of the inner wall of the collection box, a threaded rod screwed to the center of the bottom support plate, and a heat insulation plate that rotates to the top of the threaded rod. The top of the heat insulation plate and the bottom of the container are fixedly connected.

[0015] The beneficial effects of this invention are: This invention achieves adaptive positioning and fixation of test tubes of various specifications through the cooperation of a housing component, a support component, an adapter component, a track component, a fixing component, an elastic component, an adjustment component, and their subsequent structures. It can also be adjusted to accommodate test tubes of various heights and is convenient to use and place. Attached Figure Description

[0016] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the following description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the overall device for collecting waste liquid and discarded samples from pharmacokinetic studies.

[0018] Figure 2 This is a schematic diagram of a partial structure in a device for collecting waste liquid and discarded samples from pharmacokinetic studies.

[0019] Figure 3 This is a schematic diagram of the main components of a device for the centralized collection of waste liquid and discarded samples from pharmacokinetic studies.

[0020] Figure 4 This is a schematic diagram of the components in a device for collecting waste liquid and discarded samples from pharmacokinetic studies.

[0021] Figure 5 This is a schematic diagram of the supporting components in a device for the centralized collection of waste liquid and discarded samples from pharmacokinetic studies.

[0022] Figure 6 This is a schematic diagram of the adapter and fixing components in a device for centralized collection of waste liquid and discarded samples from pharmacokinetic studies.

[0023] Figure 7 This is a schematic diagram of the track and elastic components in a device for collecting waste liquid and discarded samples from pharmacokinetic experiments.

[0024] Figure 8 This is a schematic diagram of the conduction and regulation components in a device for collecting waste liquid and discarded samples from pharmacokinetic studies.

[0025] In the diagram: 100, main component; 200, housing component; 300, support component; 400, adapter component; 500, track component; 600, fixing component; 700, elastic component; 800, transmission component; 900, adjustment component; 101. Collection box; 102. Pentagonal ring; 103. Reserved slot; 104. Central tube; 201. Receiving shell; 202. No. 1 slide groove; 203. No. 2 slide groove; 204. Hollow rubber block; 205. No. 1 conical groove; 301. Expansion shell; 302. Soft block; 303. No. 2 conical groove; 304. Inclined surface; 401. Extrusion plate; 402. Driven rod; 501. Disc; 502. Arc-shaped groove; 601. Slide board; 602. Rubber roller; 701. Protruding tube; 702. Connecting block; 703. Tension spring; 704. Driven block; 801. Container tank; 802. Heat-conducting plate; 803. Multi-ring component; 901. Base plate; 902. Threaded rod; 903. Insulation plate. Detailed Implementation

[0026] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0027] Reference Figures 1-8This embodiment provides a device for the centralized collection of waste liquid and waste samples from pharmacokinetic experiments. It is adaptable to various sizes of test tubes for collection and transportation, and can achieve centered positioning and stable fixation in all cases. The device includes: a main component 100, comprising five receiving components 200 fixed to the center of the main component 100; a support component 300 sliding to the bottom of the receiving components 200; an adapter component 400 and a fixing component 600 sliding inside the receiving components 200, the adapter component 400 and the fixing component 600 being connected; a track component 500 sliding inside the adapter component 400 corresponding to the center of the main component 100; and an elastic component 700 fixed to the inner wall of the track component 500, the elastic component 700 being connected to the main component 100 and fixed to the main component. The internal structure of component 100 includes a conductive component 800 between the receiving component 200 and the supporting component 300. The conductive component 800 can be loaded with cooling objects such as dry ice to cool the test tubes inside the collection device. An adjusting component 900 slides at the bottom of the main component 100 and is connected to the conductive component 800. The test tubes are located inside the receiving component 200 and supported by the supporting component 300. Multiple sets of receiving components 200 and supporting components 300 can be used to classify and place test tubes. The conductive component 800 can then cool the test tubes. The test tubes stored in the collection device are fixed by the adapting component 400 and the fixing component 600. The height of the supporting component 300 can be adjusted by the adjusting component 900 to accommodate test tubes of various sizes for collection.

[0028] Specifically, such as Figure 3 In the main component 100, there is a collection box 101 with a pentagonal inner wall, a pentagonal ring 102 fixed inside the collection box 101, and a reserved groove 103 on each of the five sides of the pentagonal ring 102, and a central tube 104 fixed to the top of the pentagonal ring 102.

[0029] Furthermore, such as Figure 4 , 5In section 6, the receiving component 200 includes a receiving shell 201 fixed in the reserved groove 103. A first groove 202 is provided inside the receiving shell 201. A second groove 203 is provided inside the receiving shell 201 corresponding to the top of the first groove 202. A hollow rubber block 204 is fixed at the opening of the receiving shell 201. The opening end of the hollow rubber block 204 is located at one end of the first groove 202. A first conical groove 205 is provided at the end of the hollow rubber block 204. Each hollow rubber block 204 has three sections, each capable of holding three test tubes. A first conical groove 205 is located at one end of a first sliding groove 202, with the other end being conical. The support assembly 300 includes an expansion shell 301 that slides along the bottom of the receiving shell 201, and a soft block 302 fixed to the opening of the expansion shell 301 corresponding to the bottom of the hollow rubber block 204. The soft block 302 has a second conical groove 303 at the bottom of the first conical groove 205. The shape and size are consistent with the first conical groove 205. The soft block 302 is located inside the second conical groove 303 and has an inclined surface 304. The bottom surface of the inclined surface 304 is located at the conical end of the second conical groove 303, and the high surface is located at the open end of the second conical groove 303. The adapter component 400 includes a compression plate 401 that slides in the first groove 202. The compression plate 401 has a rubber surface at one end of the first conical groove 205, and a driven rod 40 is fixed to the top of the compression plate 401. 2. In use, the test tube is placed in the three first conical grooves 205 of the hollow rubber block 204, with the bottom of the test tube located in the second conical groove 303 of the soft block 302. The inclined surface 304 of the second conical groove 303 can guide the bottom of the test tube into the second conical groove 303. When the extrusion plate 401 moves into the first conical groove 205, the middle part of the test tube will be squeezed into the first conical groove 205, thereby positioning and fixing test tubes of various specifications.

[0030] Furthermore, such as Figure 6 , 7 In the middle, the track assembly 500 includes a disc 501 located on the top of the extrusion plate 401 corresponding to the center of the collection box 101. An arc-shaped groove 502 is provided on the end face of the disc 501 corresponding to the driven rod 402. The arc-shaped groove 502 is inclined on the disc 501. Figure 7As shown, the fixing component 600 includes a slide plate 601 that slides within the second slide groove 203. The bottom of the slide plate 601 and the top of the driven rod 402 are fixedly connected. A rubber roller 602 rotates at the outer end of the slide plate 601. The diameter of the rubber roller 602 is the same as the thickness of the slide plate 601. During use, when the disc 501 rotates clockwise, the driven rod 402, the extrusion plate 401, the slide plate 601, and the rubber roller 602 within the arc groove 502 are driven to move outward. The extrusion plate 401 extrudes and positions the test tube. When the roller-shaped surface of the rubber roller 602 contacts the top of the test tube, it can press the test tube downward to a certain extent. During this process, the test tube will press against the soft block 302, thus making the test tube more stable. The rubber roller 602 is located at the top of the test tube. The receiving component 200, the supporting component 300, and the rubber roller 602 can form a fixing effect on the test tube.

[0031] Furthermore, such as Figure 7 In the process, the elastic component 700 includes a protruding tube 701 fixed to the inner wall of the disc 501, the inner wall of the protruding tube 701 being rotatably connected to the outer wall of the central tube 104, a connecting block 702 fixed to the inner wall of the protruding end of the top of the protruding tube 701, a tension spring 703 fixed to the end face of the connecting block 702, and a driven block 704 fixed to the end of the tension spring 703, the inner side of the driven block 704 being fixedly connected to the outer wall of the central tube 104. In use, by rotating the protruding tube 701 counterclockwise, the connecting block 702 is driven to pull the tension spring 703. During this process, the protruding tube 701 will drive the disc 501 and its subsequent structures to rotate counterclockwise. When the protruding tube 701 is released, the tension spring 703 will drive the connecting block 702, the protruding tube 701, the disc 501 and its subsequent structures to reset.

[0032] Furthermore, such as Figure 8 In the process, the conductive component 800 includes a container 801 fixed to the inner wall of the central tube 104. The container 801 has a plug on top and is made of copper. Dry ice or other cooling substances can be added into it during use. A heat-conducting plate 802, also made of copper, is fixed to the outer wall of the container 801 corresponding to the bottom of the container component 200. A multi-ring component 803, also made of copper, is fixed to the end of the heat-conducting plate 802. The multi-ring component 803 has three annular grooves, the positions of which are adapted to the bottom of three No. 1 conical grooves 205. The multi-ring component 803 is made of copper. During use, the test tube, located in the container component 200 and the support component 300, has its middle part located in the annular groove of the multi-ring component. By adding dry ice or other cooling substances into the container 801, the copper properties of the container 801, the heat-conducting plate 802, and the multi-ring component 803 can quickly cool the test tube, avoiding the problem of excessive temperature during transportation.

[0033] Furthermore, such as Figure 8In the middle, the adjustment component 900 includes a bottom support plate 901 that slides on the bottom of the inner wall of the collection box 101, a threaded rod 902 screwed to the center of the bottom support plate 901, and a heat insulation plate 903 that rotates on the top of the threaded rod 902. The heat insulation plate 903 is made of heat insulation material. The top of the heat insulation plate 903 is fixedly connected to the bottom of the container 801. In use, by rotating the threaded rod 902 at the bottom of the heat insulation plate 903 at the bottom of the container 801, the bottom support plate 901 on the outer wall of the threaded rod 902 moves up and down, thereby adjusting the height of the expansion shell 301 and the soft block 302 on the top of the bottom support plate 901, so as to adapt to test tubes of different heights.

[0034] Working principle of the invention: When test tubes need to be placed, the protruding tube 701 is rotated counterclockwise to drive the connecting block 702 to pull the tension spring 703. During this process, the protruding tube 701 will drive the disc 501 and its subsequent structure to rotate counterclockwise. The disc 501 will drive the driven rod 402, the extrusion plate 401, the slide plate 601, and the rubber roller 602 to retract into the first slide groove 202 and the second slide groove 203. At this time, the test tubes can be placed in the three first conical grooves 205 of the hollow rubber block 204. Multiple sets of receiving components 200 can classify and place the test tubes. The bottom of the test tube is located in the second conical groove 303 of the soft block 302. The inclined surface 304 of the second conical groove 303 can guide the bottom of the test tube into the second conical groove 303. When the extrusion plate 401 moves into the first conical groove 205, the middle part of the test tube will be squeezed into the first conical groove 205, thereby positioning and fixing test tubes of various specifications. When the protruding tube 701 is released, the tension spring 703 will drive the connecting block 702, the protruding tube 701, and the disc 501 to rotate clockwise and reset. During the rotation of the disc 501, the driven rod 402, the extrusion plate 401, the slide plate 601, and the rubber roller 602 in the arc groove 502 will be driven to move outward. The extrusion plate 401 will extrude and position the test tube. When the roller-shaped surface of the rubber roller 602 contacts the top of the test tube, it can press the test tube downward to a certain extent. During this process, the test tube will press the soft block 302, which will make the test tube more stable. Since the rubber roller 602 is at the top of the test tube, the receiving component 200, the supporting component 300, and the rubber roller 602 can form a fixing effect on the test tube. When the disc 501 rotates, the arc groove 502 can drive the driven rod 402, the extrusion plate 401, the slide plate 601, and the rubber roller 602 to move until the extrusion plate 401 extrudes the test tube and stops when it touches the cone of the first conical groove 205. Therefore, in conjunction with the first conical groove 205 of the hollow rubber block 204 and the second conical groove 303 and inclined surface 304 of the soft block 302, the adaptive positioning and fixing of test tubes of various specifications can be achieved. When the test tube height is not suitable, the bottom support plate 901 on the outer wall of the threaded rod 902 is rotated at the bottom of the insulation plate 903 at the bottom of the container 801, thereby adjusting the height of the expansion shell 301 and the soft block 302 on the top of the bottom support plate 901 to accommodate test tubes of different heights.

[0035] In summary, through the combination of the housing component 200, support component 300, adapter component 400, track component 500, fixing component 600, elastic component 700, adjustment component 900 and their subsequent structures, the adaptive positioning and fixing effect of test tubes of various specifications can be achieved. It can also be adjusted to adapt to test tubes of various heights, and is convenient to use and place.

[0036] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A device for centralized collection of waste liquid and discarded samples from pharmacokinetic experiments, characterized in that, include: The main body assembly (100) includes five receiving components (200) fixed in the middle of the main body assembly (100), a support component (300) sliding at the bottom of the receiving components (200), an adapter component (400) and a fixing component (600) sliding inside the receiving components (200), the adapter component (400) and the fixing component (600) being connected, a track component (500) sliding inside the adapter component (400) corresponding to the center of the main body assembly (100), an elastic component (700) fixed to the inner wall of the track component (500), the elastic component (700) being connected to the main body assembly (100), a conduction component (800) fixed inside the main body assembly (100) corresponding to the receiving components (200) and the support component (300), and an adjustment component (900) sliding at the bottom of the main body assembly (100), the adjustment component (900) being connected to the conduction component (800).

2. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 1, characterized in that: The main component (100) includes a collection box (101), a pentagonal ring (102) fixed inside the collection box (101), the five sides of the pentagonal ring (102) are provided with reserved grooves (103), and a central tube (104) fixed to the top of the pentagonal ring (102).

3. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 2, characterized in that: The receiving component (200) includes a receiving shell (201) fixed in the reserved groove (103), a first groove (202) is provided on the inner side of the receiving shell (201), a second groove (203) is provided on the top of the first groove (202) on the inner side of the receiving shell (201), a hollow rubber block (204) is fixed at the opening of the receiving shell (201), and a first conical groove (205) is provided at the end of the hollow rubber block (204).

4. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 3, characterized in that: The support assembly (300) includes an expansion shell (301) that slides at the bottom of the receiving shell (201), and a soft block (302) fixed at the opening of the expansion shell (301) corresponding to the bottom of the hollow rubber block (204). The soft block (302) has a second conical groove (303) at the bottom of the first conical groove (205), and the soft block (302) has an inclined surface (304) inside the second conical groove (303).

5. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 4, characterized in that: The adapter assembly (400) includes an extrusion plate (401) that slides within the first groove (202) and a driven rod (402) fixed to the top of the extrusion plate (401).

6. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 5, characterized in that: The track assembly (500) includes a disc (501) located at the top of the extrusion plate (401) corresponding to the center of the collection box (101), and the end face of the disc (501) is provided with an arc groove (502) corresponding to the driven rod (402).

7. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 6, characterized in that: The fixing component (600) includes a slide plate (601) that slides within the second slide groove (203). The bottom of the slide plate (601) and the top of the driven rod (402) are fixedly connected. A rubber roller (602) rotates at the outer end of the slide plate (601). The diameter of the rubber roller (602) is the same as the thickness of the slide plate (601).

8. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 7, characterized in that: The elastic component (700) includes a protruding tube (701) fixed to the inner wall of the disc (501), the inner wall of the protruding tube (701) being rotatably connected to the outer wall of the central tube (104), a connecting block (702) fixed to the inner wall of the protruding end of the top of the protruding tube (701), a tension spring (703) fixed to the end face of the connecting block (702), and a driven block (704) fixed to the end of the tension spring (703), the inner side of the driven block (704) being fixedly connected to the outer wall of the central tube (104).

9. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 2, characterized in that: The conductive assembly (800) includes a receiving tank (801) fixed to the inner wall of the central tube (104), a heat-conducting plate (802) fixed to the outer wall of the receiving tank (801) corresponding to the bottom of the receiving assembly (200), and a multi-ring component (803) fixed to the end of the heat-conducting plate (802).

10. The pharmacokinetic test waste liquid and waste sample collection device as described in claim 2, characterized in that: The adjustment assembly (900) includes a bottom support plate (901) that slides on the bottom of the inner wall of the collection box (101), a threaded rod (902) screwed to the center of the bottom support plate (901), and a heat insulation plate (903) that rotates on the top of the threaded rod (902). The top of the heat insulation plate (903) is fixedly connected to the bottom of the container (801).

Images