An anti-leaching adhesive, an antibacterial agent, an antiviral agent, a nonwoven fabric, and a method for manufacturing the same

Abstract

The present application relates to a kind of anti-leaching adhesive, antibacterial agent, antiviral agent, non-woven fabric and its preparation method, wherein the anti-leaching adhesive includes the polysaccharide adhesive of sphingomonad with mass concentration of 65-85% and the amphiphilic water-based glue with mass concentration of 15-35%, the amphiphilic water-based glue uses the PEG-CO-P (MMA-co-EA-co-BA) block copolymer solution with mass concentration of 0.10-0.20%;The adhesive prepared by the polysaccharide adhesive of sphingomonad and the amphiphilic water-based glue compound not only has very high adhesion to non-woven fabric, can avoid the shedding of antibacterial / antiviral coating on non-woven fabric, it can also prevent the elution of antibacterial / antiviral agent, realizes the preparation of non-elution type antibacterial / antiviral non-woven fabric using adhesive load antibacterial / antiviral agent, simplifies the preparation process of non-elution type antibacterial / antiviral non-woven fabric.

Description

Technical Field

[0001] This invention belongs to the field of antibacterial nonwoven fabric technology, specifically relating to an anti-leaching adhesive, an antibacterial agent, an antiviral agent, a nonwoven fabric, and a method for preparing the same. Background Technology

[0002] Disposable hygiene products made from non-woven fabrics, such as diapers and sanitary napkins, are used for human excrement and intimate care. To prevent leakage, the entire product employs leak-proof measures, resulting in a relatively high temperature and humidity environment between the product and the intimate area. Since human excrement serves as a food source for bacteria, it easily creates an environment for bacterial growth. Therefore, antibacterial non-woven fabrics are receiving increasing attention in the development of personal hygiene products.

[0003] The current methods for preparing antibacterial / antiviral nonwoven fabrics are as follows: 1) Adding antibacterial / antiviral agents during the preparation of resin masterbatch. The advantage is that the antibacterial / antiviral agents are not easily dissolved, but the disadvantage is that most of the antibacterial / antiviral agents exist inside the nonwoven fibers and the surface content is very small, resulting in poor antibacterial or antiviral effects. In addition, this method can only prepare antibacterial / antiviral fibers with high molecular weight chemical fiber properties, and is not applicable to natural fibers, thus having a narrow scope of application. 2) Loading antibacterial / antiviral agents onto the surface of nonwoven fibers using a polysiloxane layer has the advantage of being less prone to dissolution. However, it requires the polysiloxane layer for transfer, thus limiting its applicability to fibers containing specific active groups. Furthermore, the chemical bonding of the polysiloxane layer and the loading of the antibacterial agent involve complex chemical reactions, requiring strict control of reaction precision, resulting in high technical and operational difficulty. 3) Spraying an adhesive containing antibacterial / antiviral agents onto the surface of the nonwoven fabric, using the adhesive to load the antibacterial / antiviral agents onto the nonwoven fabric surface, has the advantage of being suitable for antibacterial / antiviral applications on various nonwoven materials. The method is simple and easy to operate; however, its disadvantages are: antibacterial / antiviral agents can dissolve in water or excrement, and the dissolution of antibacterial / antiviral agents is uncontrollable. The dissolved antibacterial / antiviral agents can come into contact with the human private parts, causing skin allergies, and in severe cases, skin damage. There is even a risk of entering the human private parts, thus posing a safety hazard. Therefore, only some safe and mild antibacterial / antiviral agents can be used. In particular, for antibacterial agents, the antibacterial effect of natural materials is usually limited, while some strong antibacterial agents, such as nano-platinum antibacterial agents, cannot be used due to dissolution problems. Therefore, the improvement of the antibacterial effect of non-woven fabrics is limited.

[0004] Therefore, developing an anti-leaching adhesive to load antibacterial / antiviral agents into antibacterial / antiviral nonwoven fabrics, thereby reducing the leaching of antibacterial agents in the fabrics, is crucial for expanding the range of antibacterial / antiviral agents that can be used in nonwoven fabrics, improving the antibacterial / antiviral and anti-aging effects of nonwoven fabrics, and obtaining a simple and easy-to-operate process for preparing antibacterial / antiviral nonwoven fabrics. Summary of the Invention

[0005] The purpose of this invention is to overcome the defects in the prior art and provide an anti-leaching adhesive, antibacterial agent, antiviral agent, nonwoven fabric and its preparation method, which can prevent the leaching of antibacterial / antiviral agents on antibacterial / antiviral nonwoven fabrics, expand the selection range of antibacterial and antiviral agents, and improve the anti-aging effect and antibacterial / antiviral effect of antibacterial / antiviral nonwoven fabrics.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is as follows: An anti-leaching adhesive comprises 65-85% by mass of Sphingomonas polysaccharide adhesive and 15-35% by mass of amphiphilic waterborne adhesive, wherein the amphiphilic waterborne adhesive is a PEG-CO-P (MMA-co-EA-co-BA) block copolymer solution.

[0007] As a further technical solution, the mass concentration of the PEG-CO-P(MMA-co-EA-co-BA) block copolymer solution is 0.10-0.20% (preferably 0.15%).

[0008] As a further technical solution, the mass ratio of Sphingosine Monoclonal polysaccharide adhesive to amphiphilic aqueous adhesive is 1-8:1 (preferably 4:1).

[0009] As a further technical solution, the preparation method of Sphingosine Monoclonal polysaccharide includes the following steps: Step 1: Pretreatment of fermentation broth: Adjust the pH of the *Sphingomonas* fermentation broth to 6-8, then add lysozyme and stir for 3-5 hours to enzymatically hydrolyze and break down cell walls; then heat the fermentation broth (maintain at 130-140℃ for 5-8 minutes) to inactivate the enzymes; after the fermentation broth cools to 60-70℃, add acidic protease for enzymatic hydrolysis (enzymatic hydrolysis reaction at pH 3-4 and 50-60℃ for 2-4 hours) to degrade residual proteins; obtain the pretreated fermentation broth. Step 2, precipitant and solid-liquid separation: Add precipitation solvent (ethanol) to the pretreated fermentation broth until the precipitant concentration is ≥25% (preferably 40-75%), adjust the pH to 8.0-9.5, stir to precipitate the polysaccharide, separate the solid and liquid to obtain the precipitate; then use the precipitation solvent to purify the precipitate multiple times to obtain the polysaccharide extract. Step 3: After drying the obtained polysaccharide extract, pulverize it to obtain Sphingosine Monoclonal polysaccharide.

[0010] As a further technical solution, the preparation method of the amphiphilic waterborne adhesive includes the following steps: Step 1, Polymerization: Under nitrogen protection, anhydrous toluene, methyl methacrylate, ethyl acrylate, butyl acrylate, and polyethylene glycol monomethyl ether-2-bromoisobutyrate are added sequentially to a dry reaction vessel. After thorough stirring, cuprous bromide (15 mg) and pentamethyldiethylenetriamine (20 μL) are added under a nitrogen stream. The reaction is then stirred at 60-80°C (preferably 70°C) for 6-10 h (preferably 8 h) before the reaction is terminated to obtain the reaction product.

[0011] Step 2, Post-processing: After the reaction product is cooled to room temperature, n-hexane is added dropwise. After the precipitate is formed, the precipitate is collected and dried to constant weight to obtain PEG-CO-P(MMA-co-EA-co-BA) block copolymer; Step 3, Resolution: Dissolve the PEG-CO-P(MMA-co-EA-co-BA) block copolymer in ethyl acetate solvent to prepare a copolymer solution, and obtain an amphiphilic waterborne adhesive.

[0012] An anti-leaching antibacterial agent for nonwoven fabrics comprises 8-15 parts by weight of a nano-platinum antibacterial agent and 1-3 parts by weight of the anti-leaching adhesive; the mass concentration of the nano-platinum antibacterial agent is 0.64-1.2%.

[0013] As a further technical solution, a nonwoven fabric anti-leaching antibacterial agent also includes 0-3 parts by weight (0.5-2 parts by weight) of an odor-removing agent.

[0014] As a further technical solution, the odor-removing agent is a cucurbitacin odor-removing agent (aqdot Aqfresh).

[0015] A method for preparing the aforementioned anti-leaching antibacterial agent for nonwoven fabrics includes the following steps: Nano-platinum antibacterial agent is added to the anti-leaching adhesive, and deodorizing agent is selectively added. After stirring evenly, an anti-leaching platinum antibacterial agent for non-woven fabrics is obtained.

[0016] A method for preparing an anti-leaching antibacterial nonwoven fabric includes the following steps: After spraying the anti-leaching antibacterial agent onto the nonwoven fabric and drying it, the anti-leaching antibacterial nonwoven fabric is obtained.

[0017] An anti-leaching antiviral agent for nonwoven fabrics, comprising 8-15 parts by weight of an antiviral agent and 1-3 parts by weight of the aforementioned anti-leaching adhesive; The antiviral agent is a modified alginate.

[0018] As a further technical solution, the modified alginate is prepared by blending 2-5 parts by weight of glycerol, 2-5 parts by weight of polyethylene glycol and 4-10 parts by weight of alginate.

[0019] A method for preparing an anti-leaching antiviral agent for nonwoven fabrics includes the following steps: adding the antiviral agent to an anti-leaching adhesive and stirring evenly to obtain an anti-leaching antiviral agent for nonwoven fabrics.

[0020] A method for preparing an anti-leaching, antiviral nonwoven fabric includes the following steps: After spraying the aforementioned anti-leaching antiviral agent onto the nonwoven fabric and drying it, the anti-leaching antiviral nonwoven fabric is obtained.

[0021] Compared with the prior art, the beneficial effects of the present invention are as follows: This invention utilizes an adhesive prepared by combining an amphiphilic waterborne adhesive with Sphingomonas polysaccharide adhesive. This adhesive not only exhibits extremely high adhesion to nonwoven fabrics, preventing the antibacterial / antiviral coating from peeling off, but also provides excellent fixation and loading of antibacterial / antiviral agents, preventing their leaching. This enables the preparation of non-leaching antibacterial / antiviral nonwoven fabrics using adhesives loaded with antibacterial / antiviral agents. This simplifies the preparation process of non-leaching antibacterial / antiviral nonwoven fabrics, relaxes restrictions on nonwoven fabric materials, and provides good anti-aging properties and excellent antibacterial / antiviral performance. Detailed Implementation

[0022] The technical solution of the present invention will be clearly and completely described below with reference to specific embodiments. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0023] 1. Preparation of nano-platinum antibacterial agent: 1) Preparation of platinum ion solution: Trehalose and maltodextrin were added to water and stirred to dissolve. Then, hexachloroplatinate was added to prepare a platinum ion solution. The concentration of platinum ions (hexachloroplatinate) in the platinum solution was 0.25 mol / L, the concentration of trehalose was 2 g / 100 mL, and the concentration of maltodextrin was 10 g / 100 mL. 2) Preparation of reducing solution: Dissolve citric acid and sodium borohydride powder in water in different proportions to obtain reducing solution B; 3) Preparation of citric acid solution: Prepare a citric acid solution with a concentration of 7wt%; 4) Under ultrasonic irradiation and medium-speed stirring, add solution B to solution A so that the molar mass of trehalose and maltodextrin in the mixture is greater than or equal to that of platinum ions; after stirring with an electric stirrer for 15 minutes, add a 7wt% citric acid solution, stir thoroughly, react for 70 minutes, and then irradiate under ultraviolet light with a wavelength of 254nm and a power of 600W for 60 minutes. After the liquid cools, add water to adjust the mass concentration of the nano-platinum particles to 0.8%, thus obtaining a nano-platinum antibacterial agent with a mass concentration of 0.8%.

[0024] 2. Sphingomonas fermentation broth: Sphingomonas is fermented to obtain sphingomonas fermentation broth.

[0025] 3. A method for preparing Sphingosine Monoclonal polysaccharide adhesive, comprising the following steps: Step a, Pretreatment of fermentation broth: Adjust the pH of the *Sphingomonas* fermentation broth to 6-8, then add 100,000 U / g lysozyme until the final concentration of lysozyme is 100-200 ppm. Stir and react for 3-5 hours to enzymatically break down the cell walls. Then heat the fermentation broth to 130-140℃ and maintain for 5-8 minutes to inactivate the enzyme. After the fermentation broth cools to 60-70℃, add acidic protease and react at pH 3-4 and 50-60℃ for 2-4 hours to degrade residual proteins. Filter to remove the enzymes; the pretreated fermentation broth is obtained. Step b, precipitant and solid-liquid separation: Add precipitation solvent A (85% ethanol solution) to the pretreated fermentation broth at a volume ratio of 1:0.5-0.6, adjust the pH to 8.0-9.5, stir to precipitate the polysaccharide, centrifuge at 5000 rpm to obtain the precipitate; then wash the precipitate multiple times with precipitation solvent A (85% ethanol solution) to obtain the polysaccharide extract. Step c: After drying the obtained polysaccharide extract at 70-90℃, pulverize it to 80-100 mesh to obtain Sphingomonas polysaccharide (purity ≥98%).

[0026] 4. A method for preparing amphiphilic water-based adhesives, comprising the following steps: Step a, Polymerization: Under nitrogen protection, anhydrous toluene (10.0 mL), methyl methacrylate (1.50 g), ethyl acrylate (1.05 g), butyl acrylate (1.28 g), and polyethylene glycol monomethyl ether-2-bromoisobutyrate (0.50 g) were added sequentially to a dry 50 mL reaction vessel. After thorough stirring, cuprous bromide (15 mg) and pentamethyldiethylenetriamine (20 μL) were added under a nitrogen stream. The reaction was then stirred at 70 °C for 8 h, and the reaction was terminated to obtain the reaction product.

[0027] Step b, post-treatment: After the reaction product is cooled to room temperature, n-hexane is added dropwise. After the precipitate is precipitated, the precipitate is collected and dried to constant weight to obtain PEG-CO-P(MMA-co-EA-co-BA) block copolymer. Step c, Resolution: Add 1.5 kg of PEG-CO-P (MMA-co-EA-co-BA) block copolymer to ethyl acetate solvent (1000 L), heat and stir to dissolve, and obtain copolymer solution, i.e. amphiphilic waterborne adhesive (the mass concentration of PEG-CO-P (MMA-co-EA-co-BA) block copolymer is 0.15%).

[0028] 4. Chitosan antibacterial agent: Model MSEAB-610, purchased from Takamatsu, Japan; 5. Chitosan-based adhesive: Model NV-H1, purchased from Zhongke Lide; 6. Water-based polyurethane adhesive: Model BT5400, purchased from Hebei Bangtai; 7. Silicone-based water-based adhesive: Model KL172, purchased from Shenzhen Kanglibang; 8. Alginate: Purchased from Qingdao Mingyue Seaweed Group; 9. Polyethylene glycol 4000 (PEG4000), purchased from Suzhou Kening Polyol. 10. Antiviral agent: Modified alginate, the preparation method of which includes the following steps: Glycerin, polyethylene glycol 4000 and alginate were blended in a mass ratio of 1:1:2 to obtain modified alginate.

[0029] 11. Unless otherwise specified, all raw materials used in this invention are commercially available.

[0030] Example 1 1. An anti-leaching adhesive, the preparation method of which includes the following steps: Take 35 parts by weight of amphiphilic water-based adhesive and add 65 parts by weight of Sphingomonas polysaccharide adhesive, stir evenly to obtain an anti-dissolution adhesive.

[0031] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Take 8 parts by weight of nano-platinum antibacterial agent with a mass concentration of 0.8% and add it to 1 part by weight of anti-leaching adhesive. Stir evenly to obtain anti-leaching platinum antibacterial agent for non-woven fabric.

[0032] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: The nonwoven fabric is uniformly sprayed with a platinum antibacterial agent that prevents leaching, and then dried at 100-120℃ to form an antibacterial coating, thus obtaining an antibacterial nonwoven fabric.

[0033] Example 2 1. An anti-leaching adhesive, the preparation method of which includes the following steps: Take 15 parts by weight of amphiphilic water-based adhesive and add 85 parts by weight of Sphingomonas polysaccharide adhesive, stir evenly to obtain an anti-dissolution adhesive.

[0034] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Take 15 parts by weight of nano-platinum antibacterial agent with a mass concentration of 0.8% and add it to 3 parts by weight of anti-leaching adhesive. Stir evenly to obtain anti-leaching platinum antibacterial agent for non-woven fabric.

[0035] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0036] Example 3 1. An anti-leaching adhesive, the preparation method of which includes the following steps: Take 20 parts by weight of amphiphilic water-based adhesive and add 80 parts by weight of Sphingomonas polysaccharide adhesive, stir evenly to obtain an anti-dissolution adhesive.

[0037] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Take 12 parts by weight of nano-platinum antibacterial agent with a mass concentration of 0.8% and add it to 2 parts by weight of anti-leaching adhesive. Stir evenly to obtain anti-leaching platinum antibacterial agent for non-woven fabrics.

[0038] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0039] Example 4 1. An anti-leaching adhesive, the preparation method of which includes the following steps: same as in Example 1.

[0040] 2. A nonwoven fabric anti-leaching antiviral agent, the preparation method of which includes the following steps: Take 10 parts by weight of antiviral agent modified alginate and add it to 3 parts by weight of anti-leaching adhesive. Stir well to obtain anti-leaching antiviral agent for non-woven fabrics.

[0041] 3. An antiviral nonwoven fabric, the preparation method of which includes the following steps: uniformly spraying an anti-leaching antiviral agent onto the surface of the nonwoven fabric, and then drying it at a temperature of 100-120℃ to form an antiviral coating, thereby obtaining the antiviral nonwoven fabric.

[0042] Example 5 1. An anti-leaching adhesive, the preparation method of which includes the following steps: Take 20 parts by weight of amphiphilic water-based adhesive and add 80 parts by weight of Sphingomonas polysaccharide adhesive, stir evenly to obtain an anti-dissolution adhesive.

[0043] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Take 12 parts by weight of nano-platinum antibacterial agent with a mass concentration of 0.8% and 1.2 parts by weight of cucurbitacin deodorizing agent (aqdot Aqfresh), add them to 2 parts by weight of anti-leaching adhesive, stir evenly, and obtain anti-leaching platinum antibacterial agent for non-woven fabric (which also has deodorizing function).

[0044] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0045] Comparative Example 1 1. An anti-leaching adhesive, the preparation method of which includes the following steps: same as in Example 1.

[0046] 2. An antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: the same as in Example 1, except that: a chitin antibacterial agent with a mass concentration of 10% is used to replace the nano-platinum antibacterial agent with a mass concentration of 0.8% in Example 1.

[0047] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0048] Comparative Example 2 1. An adhesive, the preparation method of which includes the following steps: the same as in Example 1, except that a chitosan-based adhesive is used instead of the Sphingomonas polysaccharide adhesive in Example 1.

[0049] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: same as in Example 1.

[0050] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0051] Comparative Example 3 1. An adhesive, the preparation method of which includes the following steps: the same as in Example 1, except that a starch solution with a mass concentration of 10% is used to replace the amphiphilic adhesive in Example 1.

[0052] 2. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which is the same as in Example 1.

[0053] 3. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0054] Comparative Example 4 1. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Same as Example 1, except that: The anti-leaching adhesive of Example 1 was replaced with a commercially available water-based polyurethane adhesive.

[0055] 2. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0056] Comparative Example 5 1. A platinum antibacterial agent for nonwoven fabrics, the preparation method of which includes the following steps: Same as Example 1, except that: The anti-leaching adhesive of Example 1 was replaced with a commercially available silicone-based water-based adhesive.

[0057] 2. An antibacterial nonwoven fabric, the preparation method of which includes the following steps: same as in Example 1.

[0058] Comparative Example 6 An anti-leaching adhesive, the preparation method of which includes the following steps: same as in Example 1.

[0059] A nonwoven fabric, the preparation method of which includes the following steps: uniformly spraying an anti-leaching adhesive onto the surface of the nonwoven fabric, and then drying it at a temperature of 100-120 degrees Celsius to form an adhesive coating that does not contain antibacterial agents and antiviral agents, thereby obtaining the nonwoven fabric.

[0060] Example 1: Antibacterial agent adhesion test The abrasion resistance of the antibacterial / antiviral coatings on the antibacterial / antiviral nonwoven fabrics were tested separately, and the results are shown in Table 1. Abrasion resistance test: According to GB / T 21196.3-2007 "Textiles - Martindale method for determination of abrasion resistance of fabrics - Part 3: determination of mass loss", the nonwoven fabric to be tested was cut into circular samples with a diameter of 50 mm, 5 samples per group, weighed, and the average value was calculated and recorded as M0. Then, it was rubbed 120 times under a pressure of 9 kPa, weighed again, and the average value was calculated and recorded as M1. The average abrasion rate was calculated using M0 and M1.

[0061] Table 1

[0062] As shown in Table 1, the antibacterial / antiviral coatings prepared using the anti-leaching adhesive of this invention in Examples 1 and 4 exhibit significantly better adhesion than the coatings prepared using the adhesives in Comparative Examples 2-5. The anti-leaching adhesive of this invention effectively prevents the aging of antibacterial and antiviral agents. Although Comparative Example 1 also uses the anti-leaching adhesive of this invention, its wear rate is higher than that of Examples 1 and 4 because the chitin antibacterial agent has a relatively large particle size and is not wear-resistant, and the adhesive cannot completely encapsulate the chitin.

[0063] Example 2: Anti-aging test The initial antibacterial rate / initial antiviral rate of the antibacterial nonwoven fabric was tested, as well as the antibacterial rate / antiviral rate after aging for 14 days (simulated storage for 1 year), 90 days (simulated storage for 2 years), and 180 days (simulated storage for 3 years). The results are shown in Table 2. The aging method refers to Appendix E7, Stability Test, of GB15979-2024. Test method for antibacterial rate: Refer to Appendix E6.4 of GB15979-2024 for inhibition zone (non-dissolution method test), and use Candida albicans as the test bacteria; Test method for antiviral rate: Sample pretreatment was performed according to GB / T43823-2024, and HPV virus detection was performed according to YY / T1226-2022 "Human Papillomavirus Nucleic Acid (Type) Detection Kit"; Table 2

[0064] As can be seen from the data in Table 2, the nonwoven fabric prepared by the present invention, due to the use of an anti-leaching adhesive, allows for the selection of antiviral and antibacterial agents with excellent aging resistance. Compared with antibacterial and antiviral agents with poor aging resistance, the prepared antibacterial / antiviral nonwoven fabric has a longer shelf life.

[0065] Example 3: Dissolution of antibacterial / antiviral agents The leaching of the antibacterial / antiviral nonwoven fabrics in each embodiment and comparative example was tested, and the results are shown in Table 3. Test method: (1) Preparation of dissolution solution: Cut the antibacterial / antiviral nonwoven material into 10 mm × 10 mm sample pieces, weigh 0.75 g in two portions and place them into 250 mL conical flasks respectively. Then add 70 mL of PBS to each conical flask. Fix the conical flasks on a shaking table and shake at 300 r / min for 2 min at 20 ℃~25 ℃. Take 0.5 mL as the dissolution solution before shaking in the test group. Continue shaking for 1 h and take 0.5 mL of the sample solution as the dissolution solution after shaking in the test group. A negative control sample piece group and a group without sample pieces are also set up. (2) Determine the antibacterial rate or antiviral rate of the dissolution solution: The dissolution rate of the antibacterial agent or antiviral agent is expressed as the antibacterial rate or antiviral rate of the dissolution solution; Antibacterial rate: The viable colony count method was used, referring to the dissolution method in Appendix E6.5 of GB15979-2024. Antiviral rate: Sample pretreatment was performed according to GB / T43823-2024, and HPV virus detection was performed according to YY / T 1226-2022 "Human Papillomavirus Nucleic Acid (Type) Detection Kit"; Table 3

[0066] As can be seen from the data in Table 3, the nonwoven fabrics of Comparative Examples 2-5 all showed varying degrees of antibacterial agent leaching, while the nonwoven fabrics prepared using the anti-leaching adhesive of the present invention, such as Examples 1, 4 and Comparative Example 1, showed no leaching of antibacterial or antiviral agents.

[0067] The embodiments described above are merely preferred embodiments of the present invention, and not an exhaustive list of all possible implementations of the present invention. Any obvious modifications made by those skilled in the art without departing from the principles and spirit of the present invention should be considered to be included within the scope of protection of the claims of the present invention.

Claims

1. An anti-leaching adhesive, characterized in that, It includes a sphingomonas polysaccharide adhesive with a mass concentration of 65-85% and an amphiphilic waterborne adhesive with a mass concentration of 15-35%, wherein the amphiphilic waterborne adhesive is a PEG-CO-P (MMA-co-EA-co-BA) block copolymer solution.

2. The anti-leaching adhesive according to claim 1, characterized in that, The mass concentration of the PEG-CO-P(MMA-co-EA-co-BA) block copolymer solution is 0.10-0.20%.

3. The anti-leaching adhesive according to claim 1, characterized in that, The preparation method of Sphingosine Monoclonal polysaccharide includes the following steps: Step 1, Pretreatment of fermentation broth: Adjust the pH of the Sphingomonas fermentation broth to 6-8, then add lysozyme and stir to carry out enzymatic hydrolysis and cell wall breaking; then heat the fermentation broth to inactivate the enzyme, and after the fermentation broth cools down to 60-70℃, add acidic protease to enzymatically degrade the residual protein; the pretreated fermentation broth is obtained. Step 2, precipitant and solid-liquid separation: Add a precipitant to the pretreated fermentation broth, adjust the pH to 8.0-9.5, stir to precipitate the polysaccharide, separate the solid and liquid, and obtain the precipitate; then use the precipitant to purify the precipitate multiple times to obtain the polysaccharide extract. Step 3: After drying the obtained polysaccharide extract, pulverize it to obtain Sphingosine Monoclonal polysaccharide.

4. The anti-leaching adhesive according to claim 1, characterized in that, The preparation method of amphiphilic waterborne adhesive includes the following steps: Step 1, Polymerization: Under nitrogen protection, anhydrous toluene, methyl methacrylate, ethyl acrylate, butyl acrylate, and polyethylene glycol monomethyl ether-2-bromoisobutyrate are added sequentially to a dry reaction vessel. After thorough stirring, cuprous bromide and pentamethyldiethylenetriamine are added under a nitrogen stream. The reaction is then carried out at 60-80℃ for 6-10 hours, and the reaction is terminated to obtain the reaction product. Step 2, Post-processing: After the reaction product is cooled to room temperature, n-hexane is added dropwise to precipitate the product. The precipitate is then collected and dried to constant weight to obtain PEG-CO-P(MMA-co-EA-co-BA) block copolymer. Step 3, Resolution: Dissolve the PEG-CO-P (MMA-co-EA-co-BA) block copolymer in ethyl acetate to prepare a copolymer solution, and obtain an amphiphilic waterborne adhesive.

5. A nonwoven fabric anti-leaching antibacterial agent, characterized in that, It comprises 8-15 parts by weight of a nano-platinum antibacterial agent and 1-3 parts by weight of the anti-leaching adhesive as described in any one of claims 1-4; the mass concentration of the nano-platinum antibacterial agent is 0.64-1.2%.

6. The anti-leaching antibacterial agent for nonwoven fabrics according to claim 5, characterized in that, It also includes 0-3 parts by weight of deodorizing agent.

7. A method for preparing an anti-leaching antibacterial agent for nonwoven fabrics as described in claim 5, characterized in that, The process includes the following steps: adding nano-platinum antibacterial agent to the anti-leaching adhesive, selectively adding deodorizing agent, and stirring evenly to obtain an anti-leaching platinum antibacterial agent for non-woven fabrics.

8. A method for preparing an anti-leaching antibacterial nonwoven fabric, characterized in that, Includes the following steps: After spraying the anti-leaching antibacterial agent of claim 5 onto the nonwoven fabric and drying it, the anti-leaching antibacterial nonwoven fabric is obtained.

9. A nonwoven fabric anti-leaching antiviral agent, characterized in that, It includes 8-15 parts by weight of an antiviral agent and 1-3 parts by weight of an anti-leaching adhesive as described in any one of claims 1-4; The antiviral agent is a modified alginate; The modified alginate is prepared by blending 2-5 parts by weight of glycerol, 2-5 parts by weight of polyethylene glycol and 4-10 parts by weight of alginate.

10. A method for preparing an anti-leaching antiviral agent for nonwoven fabrics as described in claim 9, characterized in that, The process includes the following steps: adding the antiviral agent to the anti-leaching adhesive and stirring until homogeneous to obtain an anti-leaching antiviral agent for nonwoven fabrics.

11. A method for preparing an anti-leaching, antiviral nonwoven fabric, characterized in that, Includes the following steps: After spraying the anti-leaching antiviral agent of claim 9 onto the nonwoven fabric and drying it, the anti-leaching antiviral nonwoven fabric is obtained.

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