Rotating magnetic field generating device and control method

Abstract

This application relates to the field of animal health technology and discloses a rotating magnetic field generating device and control method. The device includes: a magnetic field generating component comprising a support substrate and at least two permanent magnets with fixed magnetization directions and spaced apart from each other, the permanent magnets being spaced apart and mounted on the support substrate, which serves to support the permanent magnets as a whole; and a rotating drive mechanism for driving the magnetic field generating component to rotate around a vertical axis. The magnetic field generating component is positioned directly below the treatment area where the pet is placed to form a rotating magnetic field in the pet's abdominal region with a direction that changes over time, driving the magnetic material delivered to the organelles of the pet's abdominal tumor cells to rotate. Through this device, a stable rotating magnetic field can be formed in the animal's abdominal region, achieving precise driving of the magnetic material within the tumor cells, thereby mechanically destroying the pet's tumor cells in the target area under non-invasive conditions.

Description

Technical Field

[0001] This application relates to the field of animal health and rehabilitation medicine technology, specifically to a rotating magnetic field generating device and control method for non-invasive treatment and rehabilitation intervention in animals. Background Technology

[0002] This section is intended to provide background or context for the embodiments of this application as set forth in the claims. The content in this section is for reference only and does not constitute an admission or confirmation that it is prior art that has been disclosed.

[0003] Magnetotherapy is a non-invasive treatment method that utilizes magnetic fields to act on magnetic materials within the body to achieve disease intervention and treatment. In the field of tumor treatment, magnetic materials (such as magnetic nanoparticles) can be injected locally into tumor tissue. Guided and driven by an external magnetic field, they produce biological effects such as physical movement, tissue disturbance, and membrane damage, thereby destroying tumor cells and improving treatment efficacy. This treatment method is characterized by its ease of operation, strong targeting, and minimal tissue damage, and has become an important direction in animal tumor treatment research in recent years.

[0004] Existing magnetic therapy devices primarily focus on treatment research at the cellular level, in mouse models, or in specific localized areas, often employing complex structures such as electromagnetic coils to achieve magnetic field modulation. These devices typically suffer from limitations such as a limited magnetic field range, insufficient penetration depth, magnetic instability, bulky structure, and high manufacturing costs, restricting their practical application in companion animals, especially small to medium-sized pets (such as cats and dogs). Particularly during treatment of the abdominal region while the animal is in a natural lying position, traditional devices struggle to achieve large-scale, highly stable rotating magnetic field intervention, thus affecting the effective movement of the magnetic material and the therapeutic effect.

[0005] Besides cancer treatment, magnetic fields also show broad application prospects in rehabilitation medicine. For example, in the fields of rehabilitation of bone and joint diseases, nerve injury rehabilitation, and muscle strain rehabilitation, by applying a rotating magnetic field to implanted or injected magnetic materials, local microcirculation can be improved, cell activity enhanced, and tissue repair promoted, thereby accelerating the rehabilitation process.

[0006] Therefore, there is an urgent need to develop a magnetic therapy device with a simpler structure, more stable magnetic force, wider range of action, and adaptability to animal posture to meet the practical needs of clinical treatment and rehabilitation of solid tumors in companion animals. Summary of the Invention

[0007] The purpose of this application is to provide a rotating magnetic field generating device and control method for non-invasive tumor treatment and rehabilitation intervention in animals. It can form a stable rotating magnetic field in the abdominal region of the animal, realize the precise driving of magnetic materials in cells, and thus mechanically destroy the cells of the pet in the target area under non-invasive conditions.

[0008] This application discloses a rotating magnetic field generating device, comprising:

[0009] A magnetic field generating component includes a support substrate 1 and at least two permanent magnets 2 with fixed magnetization directions and spaced apart from each other on the support substrate 1.

[0010] Rotary drive mechanism 3 is used to drive the magnetic field generating component to rotate around the vertical axis;

[0011] The magnetic field generating component is positioned directly below the treatment area where the pet is placed to form a rotating magnetic field in the abdominal region of the pet, the direction of which changes over time, driving the magnetic material within the organelles delivered to the abdominal tumor cells of the pet to rotate.

[0012] In a preferred embodiment, the plurality of permanent magnets 2 are arranged symmetrically or in a ring around a rotation axis.

[0013] In a preferred embodiment, the plurality of permanent magnets 2 are cuboids, sectors, or circles.

[0014] In a preferred embodiment, the plurality of permanent magnets 2 are 2, 4, 6 or 8.

[0015] In a preferred embodiment, the rotating magnetic field has a central perturbation region corresponding to the midline of the pet's abdomen.

[0016] In a preferred embodiment, the permanent magnet 2 includes a first permanent magnet 21 and a second permanent magnet 22, wherein the magnetization direction of the first permanent magnet 21 is along the positive direction of the vertical direction, and the magnetization direction of the second permanent magnet 22 is along the negative direction of the vertical direction.

[0017] In a preferred embodiment, the distance between the first permanent magnet 21 and the second permanent magnet 22 is 1 cm to 10 cm; more preferably, the distance between the first permanent magnet 21 and the second permanent magnet 22 is 3 cm.

[0018] In a preferred embodiment, the rotating magnetic field is a centripetal rotating magnetic field in an approximately horizontal plane.

[0019] In a preferred embodiment, the rotating magnetic field is a vector magnetic field whose direction changes with time in a horizontal plane, used to apply periodic orientation drive to magnetic materials in the abdominal region of an animal.

[0020] In a preferred embodiment, an outer casing 5 is also provided around the periphery of the magnetic field generating component.

[0021] In a preferred embodiment, the outer shell 5 includes an animal support plate 5 disposed above the magnetic field generating component. The animal support plate 5 is a horizontal structure used to support the pet to be treated, and the abdominal region of the pet is within the range of magnetic field intervention.

[0022] In a preferred embodiment, a removable cover is provided above the animal support plate 5 to cover and limit the range of movement of small animals during treatment.

[0023] In a preferred embodiment, the effective internal volume of the enclosure is 200 cm³. 3 Up to 800cm 3 Suitable for small pets with a body length of 5cm to 12cm.

[0024] In a preferred embodiment, the cover material is a transparent or translucent material.

[0025] In a preferred embodiment, an animal restraint device is also provided on the animal support plate 5 to restrict the position of the head and limbs when the pet is awake, so as to stabilize the pet's posture during treatment.

[0026] In a preferred embodiment, the animal restraint device includes multiple flexible straps, head loops, or adjustable supports for securing the animal's limbs, torso, and head respectively.

[0027] In a preferred embodiment, the rotation frequency of the rotary drive mechanism 3 is adjustable from 0 rpm to 1000 rpm.

[0028] This application also discloses a rotating magnetic field control method for non-invasive treatment of small and medium-sized animals, comprising the following steps:

[0029] a) Provide a device as described above for placing a pet whose body has been delivered magnetic material onto the device;

[0030] b) Control the operation of the device to cause the magnetic field generating component to generate a rotating magnetic field whose direction changes with time;

[0031] c) The magnetic material is disturbed by the rotating magnetic field.

[0032] In a preferred embodiment, step a) of placing the pet, on which the magnetic material has been delivered, onto the device further includes placing the pet in a natural lying position on the animal support plate (5) of the device, such that the abdominal region of the pet is within the range of the interference of the rotating magnetic field.

[0033] In this embodiment, by mounting at least two permanent magnets with fixed magnetization directions and spaced apart from each other on a support substrate, and driving the entire assembly to rotate around a vertical axis by a rotary drive mechanism, a rotating magnetic field with a direction that changes over time is formed in the animal's abdominal region. This enables efficient driving of magnetic materials delivered into tumor cells, thereby applying continuous and controllable physical perturbation to the target tissue without contacting the animal's body surface or altering its natural position. This structure not only simplifies the magnetic field control method and improves the range and stability of the magnetic field, but also enhances the precision and safety of non-invasive intervention, making it particularly suitable for the actual treatment needs of small and medium-sized animals.

[0034] The specification of this application contains numerous technical features distributed across various technical solutions. Listing all possible combinations of these technical features (i.e., technical solutions) would make the specification excessively lengthy. To avoid this problem, the various technical features disclosed in the above-described invention, the various technical features disclosed in the following embodiments and examples, and the various technical features disclosed in the accompanying drawings can be freely combined to form various new technical solutions (all of which are considered to have been described in this specification), unless such a combination of technical features is technically infeasible. For example, one example discloses feature A+B+C, and another example discloses feature A+B+D+E. Features C and D are equivalent technical means that serve the same function, and technically only one needs to be used; they cannot be used simultaneously. Feature E can technically be combined with feature C. Therefore, the solution A+B+C+D should not be considered as described because it is technically infeasible, while the solution A+B+C+E should be considered as described. Attached Figure Description

[0035] Figure 1 This is a schematic diagram of the magnetic field generating component structure of a rotating magnetic field generating device according to one embodiment of this application.

[0036] Figure 2 This is a top view schematic diagram of the magnetic field generating component of a rotating magnetic field generating device according to one embodiment of this application.

[0037] Figure 3 This is a schematic diagram of the magnetic field line distribution of the magnetic field generating component of a rotating magnetic field generating device according to one embodiment of this application.

[0038] Figure 4 This is a schematic diagram of a rotating magnetic field generating device according to one embodiment of this application.

[0039] Figure 5 This is an explosion schematic diagram of a rotating magnetic field generating device according to one embodiment of this application.

[0040] Figure 6 This is a cross-sectional schematic diagram of a rotating magnetic field generating device according to one embodiment of this application.

[0041] Figure 7 This is a schematic diagram of the component assembly of a rotating magnetic field generating device according to one embodiment of this application.

[0042] Figure 8 This is a top view schematic diagram of a rotating magnetic field generating device according to one embodiment of this application.

[0043] Explanation of reference numerals in the attached figures:

[0044] 1-Carrier substrate; 2-Permanent magnet; 21-First permanent magnet; 22-Second permanent magnet; 3-Rotation drive mechanism; 4-Outer shell; 5-Animal carrier plate. Detailed Implementation

[0045] In the following description, many technical details are presented to help the reader better understand this application. However, those skilled in the art will understand that the technical solutions claimed in this application can be implemented even without these technical details and various variations and modifications based on the following embodiments.

[0046] The advantages of this application are briefly described below:

[0047] 1. It adopts a permanent magnet and mechanical rotation drive method, which eliminates the complex electromagnetic system, and the overall structure is compact, easy to manufacture and maintain.

[0048] 2. The permanent magnets are arranged symmetrically or in a ring to form a rotating magnetic field whose direction changes with time. This can effectively act on the pet's abdominal area, and the magnetic field formed is stable and has a wide coverage.

[0049] 3. Equipped with an animal support board, cover and restraint device, suitable for pets of different sizes and conditions, and supports pets receiving treatment with their owners while they are awake.

[0050] 4. The rotation frequency is adjustable and the magnetic field disturbance is stable, making it easy to customize treatment plans according to treatment needs.

[0051] 5. The device weighs approximately 250kg and is suitable for clinical veterinary hospitals and other similar locations. It features a compact structure, uniform magnetic field, and ease of use.

[0052] To make the objectives, technical solutions, and advantages of this application clearer, the embodiments of this application will be described in further detail below with reference to the accompanying drawings.

[0053] This application relates to a rotating magnetic field generating device, the structural diagram of which is shown below. Figure 1-8 As shown, it includes: a magnetic field generating component and a rotary drive mechanism 3.

[0054] The magnetic field generating component includes a support substrate 1 and at least two permanent magnets 2 with fixed magnetization directions and spaced apart from each other. The permanent magnets 2 are spaced apart on the support substrate 1, and the support substrate 1 is used to support the permanent magnets 2 as a whole.

[0055] The rotary drive mechanism 3 is used to drive the magnetic field generating component to rotate around the vertical axis.

[0056] The magnetic field generating component is positioned directly below the treatment area where the pet is placed to create a rotating magnetic field in the pet's abdominal region that changes direction over time, driving the magnetic material within the organelles delivered to the pet's abdominal tumor cells to rotate.

[0057] In an optional embodiment, the rotary drive mechanism 3 is a motor. The motor can be a DC motor, a stepper motor, or a servo motor to provide controllable and stable rotary driving force. The motor's speed can be adjusted by an electronic control system to adapt to different magnetic field disturbance frequencies. Optionally, the rotary drive mechanism 3 can also be a mechanical transmission structure, such as using an external manual rotation component, a pulley and belt mechanism, or a gear transmission device to drive the rotation of the magnetic field generating component. All of these structural forms can achieve a rotary output effect where the magnetic field direction changes over time, adapting to different application scenarios and cost requirements.

[0058] In an optional embodiment, the rotary drive mechanism 3 is a vertically suspended motor whose output shaft extends upward and is coaxially connected to the support plate 1 of the magnetic field generating component. To achieve stable and reliable power transmission, the motor's output shaft can be connected to the center hole of the support plate 1 or a mounting boss located at the bottom of the support plate 1 via a coupling. The coupling can be either a flexible coupling or a rigid coupling to buffer axial errors and reduce mechanical impact caused by eccentricity or vibration during transmission.

[0059] In an optional embodiment, a plurality of permanent magnets 2 are arranged symmetrically or in a ring around a rotation axis.

[0060] In an optional embodiment, the plurality of permanent magnets 2 are cuboids, sectors, or circles.

[0061] Optionally, the arrangement of the permanent magnets 2 can be flexibly adjusted according to their number and shape to optimize the magnetic field distribution. For example, when the permanent magnets 2 are two cuboid structures, they are arranged radially at intervals on both sides of the supporting substrate 1, with opposite magnetization directions (one magnetization direction facing upwards and the other downwards). The two magnets are symmetrically distributed on both sides of the rotation axis to form a periodically changing rotating magnetic field in the central region during rotation. Alternatively, when the permanent magnets 2 are four fan-shaped structures, they can be symmetrically distributed at equal angles (every 90°) around the rotation axis along the circumference, with adjacent magnets having opposite magnetization directions (NSNS alternating) to enhance the toroidal magnetic field disturbance effect. This structure helps to form a spatially uniform rotating magnetic field and reduces local magnetic field voids or excessive superposition, making it suitable for applications requiring magnetic field intervention in larger areas (e.g., larger animals).

[0062] In one optional embodiment, the number of permanent magnets 2 is 2, 4, 6, or 8. The specific number can be selected according to the size of the target animal, the size of the treatment area, and the required magnetic field strength. When the number of permanent magnets 2 is small (e.g., 2 or 4), it is suitable for local or small-area magnetic field intervention for small and medium-sized animals; when the number is large (e.g., 6 or 8), a uniform and continuous rotating magnetic field can be formed over a larger area, which is suitable for larger animals or applications requiring large-area magnetic coverage.

[0063] To ensure a stable magnetic field distribution and balanced mechanical operation during rotation, the permanent magnets 2 should be arranged in a substantially symmetrical manner. Specifically, multiple permanent magnets 2 are preferably distributed at equal angles around the rotation axis on the supporting substrate 1, making the magnets relatively balanced in geometric position and mass distribution, thereby reducing the generation of eccentric forces and uneven magnetic disturbances during rotation. For example, they should be located on opposite sides of the rotation axis to form an axisymmetric structure; or they should be evenly arranged along the circumference to form a centrally symmetrical or radially symmetrical arrangement. This substantially symmetrical arrangement not only helps to improve the uniformity and intervention effect of the magnetic field range, but also improves the structural stability and service life of the entire rotating system, avoiding mechanical vibration and wear caused by unbalanced rotation.

[0064] In an optional embodiment, the rotating magnetic field has a central perturbation region corresponding to the midline of the pet's abdomen. This central perturbation region is located around the rotation axis of the magnetic field generating component, forming a spatial region with a high magnetic field strength gradient and the most significant directional change. Preferably, this central perturbation region corresponds to the midline of the pet's abdomen, i.e., the target intervention area where the magnetic material is injected, thereby ensuring that the rotating magnetic field generates maximum orientation perturbation or rotational drive on the magnetic particles in the tumor region.

[0065] In an optional embodiment, the permanent magnet 2 includes a first permanent magnet 21 and a second permanent magnet 22, wherein the magnetization direction of the first permanent magnet 21 is along the positive direction of the vertical direction, and the magnetization direction of the second permanent magnet 22 is along the negative direction of the vertical direction.

[0066] In one optional embodiment, the distance between the first permanent magnet 21 and the second permanent magnet 22 is 1 cm to 10 cm. Preferably, the distance between the first permanent magnet 21 and the second permanent magnet 22 is 3 cm.

[0067] In an optional embodiment, the first permanent magnet 21 and the second permanent magnet 22 are provided with limiting blocks on the left and right sides or more sides, which are fixedly connected to the carrier substrate 1. The limiting blocks are used to prevent the permanent magnets from detaching from the carrier substrate 1 during rotation.

[0068] In one optional embodiment, the rotating magnetic field is a centripetal rotating magnetic field within an approximately horizontal plane. That is, the magnetic field direction rotates horizontally around the rotation axis, forming a circular motion of the magnetic field vector that changes over time. This magnetic field characteristic causes the magnetic material to be continuously oriented in the horizontal direction and exhibits a response behavior that tends towards the center of the magnetic field disturbance.

[0069] In an optional embodiment, the rotating magnetic field is a vector magnetic field whose direction rotates in a horizontal plane over time, used to apply periodic orientation drive to magnetic materials in the abdominal region of an animal.

[0070] In an optional embodiment, an outer housing 5 is further included, disposed around the periphery of the magnetic field generating component. This housing 5 encloses the rotating magnetic field generating component and its rotating drive mechanism 3, providing protection, isolation, and structural support. Preferably, the housing 5 is made of a non-magnetic material, such as high-strength plastic, aluminum alloy, or composite material, to avoid interfering with the magnetic field distribution, while also possessing good mechanical strength and corrosion resistance.

[0071] In an optional embodiment, the outer shell 5 includes an animal support plate 5 disposed above the magnetic field generating component. The animal support plate 5 is at a certain distance from the permanent magnet 2. The animal support plate 5 is a horizontal structure used to support the pet to be treated. The abdominal area of ​​the pet is within the range of magnetic field intervention.

[0072] The animal support plate 5 can be configured with different sizes or replaceable structures to meet the needs of animals of different sizes. For easy cleaning and disinfection, the support plate can be detachable, and its material is preferably a high-temperature resistant and corrosion-resistant medical-grade plastic or metal-coated material.

[0073] In another alternative embodiment, the structure of the outer casing 5 can be as follows: Figure 5As shown, this is a modular design, comprising multiple independent components such as a front cover, rear cover, left side cover, right side cover, and base plate. Each component is fixed to the frame via screws, snap-fit ​​connections, or sliding groove positioning, forming a comprehensive protective structure for the internal magnetic field generating components and rotary drive mechanism. The rear cover, together with the left and right side covers, forms the rear and side protection of the device. This modular structure facilitates the assembly, disassembly, and maintenance of the device.

[0074] In a preferred embodiment, to ensure that the midline of the animal's abdomen is accurately aligned with the central disturbance region of the magnetic field, the animal support plate 5 is provided with a positioning mark structure or positioning aid device. This positioning mark structure may include a central reference line (such as...). Figure 8 The red line, groove, scale markings, or graphic symbols shown are used to guide the operator to place the pet belly down with its body axis aligned with the reference line, so that the midline of the abdomen is exactly above the center of the magnetic field disturbance area.

[0075] In an optional embodiment, such as Figure 5 As shown, the animal support plate 5 is equipped with a detachable cover to cover and limit the range of movement of small animals during treatment. The cover is preferably arched or box-shaped with a certain internal height, allowing the animal to maintain a natural lying posture while restricting its horizontal movement or rolling behavior, preventing changes in posture from affecting the magnetic field intervention effect. In an optional embodiment, the cover material is transparent or semi-transparent, such as polycarbonate, acrylic, or other medical-grade plastics, facilitating real-time observation of the animal's condition and enabling necessary interventions. Preferably, the cover and the animal support plate 5 are detachably connected via snaps, grooves, or magnetic structures for easy installation, removal, cleaning, and replacement. In an optional embodiment, the effective internal volume of the cover is between 200 cm³ and 800 cm³. 3 It is suitable for small pets with a body length of 5cm to 12cm. Furthermore, ventilation holes can be provided on the enclosure to improve the animal's comfort during treatment and the system's expandability and compatibility.

[0076] Alternatively, the enclosure can be installed only when treating small pets (such as hamsters, mice, kittens, etc.). For medium or large pets (such as adult cats and dogs) that are larger in size and do not require special restraint during treatment, the enclosure can be removed as needed, allowing the animal to be freely placed on the animal support plate 5 in a natural lying position.

[0077] In an optional embodiment, an animal restraint device (not shown) disposed on the animal support plate 5 is also included to restrict the position of the head and limbs when the pet is awake, thereby stabilizing the pet's posture during treatment. In an optional embodiment, the animal restraint device includes multiple flexible straps, head loops, or adjustable supports for securing the animal's limbs, torso, and head respectively. The flexible straps are preferably made of medical-grade silicone or nylon webbing, possessing good flexibility and a certain degree of restraint, effectively restricting animal movement while avoiding pressure sores or irritation to the animal's skin. The head loop is used to restrict head rotation, preventing the animal from twisting excessively during treatment. Furthermore, to improve animal comfort, the restraint device can be equipped with soft padding or non-slip covering materials to reduce feelings of restraint and stress responses, thereby improving the smooth progress of treatment and animal compliance.

[0078] In an optional embodiment, an emergency stop button is provided on the housing 5, which can be manually triggered by the operator in case of an abnormality during device operation to immediately cut off the rotation drive power supply, thereby quickly stopping the rotation of the magnetic field generating component and ensuring the safety of people, animals, and equipment. Preferably, the emergency stop button is located in the side area of ​​the housing 5, specifically on the outer surface of the right side cover, close to the operator's frequently used operating side, for easy and quick access.

[0079] The emergency stop button can be a mechanical self-locking button or an electronic control switch with a reset function. Its signal can be linked with the rotary drive mechanism 3 through the control system, featuring rapid response and reliable operation. During non-invasive treatment operations using the magnetic field generator, if abnormal animal posture, abnormal device vibration, or operator misoperation occurs, the emergency stop button can serve as the first-response safety mechanism to effectively prevent accidental injury or equipment damage.

[0080] In an optional embodiment, the rotation frequency of the rotary drive mechanism 3 can be adjusted from 0 rpm to 1000 rpm. For example, in the first stage (such as the tumor destruction stage), adjusting the rotation frequency to 900 rpm can maximize the removal of residual tumor cells after surgery; while in the second stage (such as the immune activation stage), adjusting the rotation frequency to 120 rpm can activate the systemic tumor immune response and inhibit tumor growth.

[0081] The second embodiment of this application discloses a rotating magnetic field control method for non-invasive treatment of small and medium-sized animals, comprising the following steps:

[0082] a) Provide a device as described above for placing a pet whose body has been delivered with magnetic material onto the device.

[0083] b) The control device operates to cause the magnetic field generating component to produce a rotating magnetic field whose direction changes with time.

[0084] c) A rotating magnetic field is used to drive a disturbance in the magnetic material.

[0085] In an optional embodiment, step a) of placing the pet, on which the magnetic material has been delivered, onto the device further includes placing the pet in a natural lying position on the animal support plate 5 of the device, so that the abdominal region of the pet is within the range of the rotating magnetic field.

[0086] In an optional embodiment, step d) may be included, adjusting the operating parameters of the rotary drive mechanism 3, including rotation frequency, acceleration time, and continuous running time, according to a preset program or real-time feedback information, to adapt to the response characteristics of different animal sizes or magnetic materials.

[0087] In an optional embodiment, step e) may be included, setting an operating mode, such as the cycle of the rotating magnetic field, and automatically controlling it according to a predetermined operating time, interval time, or number of repetitions. For example, each operation lasts 5 minutes, with a 2-minute interval, for a total of 3 cycles.

[0088] In an optional embodiment, step f) may be included, where the rotation frequency, treatment duration, and operating mode are set via a control interface. The control interface may be a touchscreen, a physical knob, or a remote terminal (such as a PC or mobile device).

[0089] To better understand the technical solution of this application, a specific example is provided below. The details listed in this example are mainly for ease of understanding and are not intended to limit the scope of protection of this application.

[0090] Example 1

[0091] The device of this application adopts a modular structure design, mainly consisting of an outer shell 5, a magnetic field generating component, a rotary drive mechanism 3, and a bottom support structure. A horizontally arranged animal carrying platform is provided on the upper part of the outer shell 5 for placing the pet to be treated. The surface of the animal carrying platform 5 has strap holes for attaching a fixing device to achieve stable control of the animal's position. A detachable cover structure is located in the center to limit the position of small animals. The platform can be replaced or adjusted according to the animal's size.

[0092] A magnetic field generating assembly is located below the animal support plate 5. This assembly includes a support base plate 1 that supports the permanent magnet 2, and is coaxially connected to a rotary drive mechanism 3 located below the magnetic field generating assembly via a transmission shaft. The rotary drive mechanism 3 is preferably a motor, inverted and suspended, with its output shaft extending upwards. It is coupled to the magnetic field generating assembly via a coupling to achieve rotary drive of the magnetic field. The entire rotating component rotates on the vertical axis, forming a rotating magnetic field whose direction changes with time.

[0093] The device is enclosed by a shell structure consisting of a front cover, a rear cover, a left cover, and a right cover. This shell encloses the internal rotating components, creating a sealed space and enhancing safety during operation. An emergency stop switch assembly is integrated into the outer surface of the right cover. In the event of an abnormality during operation, the operator can immediately interrupt the drive mechanism using the emergency stop button, ensuring safe operation. Furthermore, a front indicator light bar is located on the front of the device to indicate the operating status, including functions such as power-on and magnetic field activation.

[0094] The entire device is mounted on a base plate support structure. The base plate is equipped with positioning holes and fixing foot pad interfaces, allowing it to be stably placed on a platform or experimental workbench. The outer shell 5 is initially determined to be made of plastic injection molding, with a uniform wall thickness of 5mm, meeting structural strength requirements while also considering manufacturability. The shell and functional components are assembled using screws, clips, or sliding grooves, facilitating later disassembly, maintenance, or replacement of core functional modules.

[0095] like Figure 1 As shown, the scheme selected in this embodiment includes two permanent magnets 2 (numbered ① and ②), which are cuboid structures with dimensions of 8cm in length, 7cm in width, and 6cm in height. The supporting substrate 1 has a radius of 12cm, a thickness of 1.5cm, and a width of 10cm, and is used to fix the two permanent magnets 2. The magnetization direction of permanent magnet ① is along the positive z-axis, and the magnetization direction of permanent magnet ② is along the negative z-axis. The two magnets maintain a distance of 3cm and are both fixed to the supporting substrate 1. Figure 2 The diagram shows the magnetic field lines generated by the magnet in the device of this application. From left to right, these are the top view, front view, and three-dimensional view. It can be seen that, under the designed magnet layout and driving conditions, the magnetic field generating component of this application can form a concentrated and symmetrical high-intensity magnetic field region at the corresponding location on the animal's abdomen. The magnetic field strength decreases gradually from the center outwards, forming a clear magnetic gradient region, thus providing a stable driving force for the rotation or vibration of magnetic materials within the body. The top, side, and three-dimensional views all verify that the geometric position of the magnetic field interference area is consistent with the design expectation, ensuring that the magnetic field's effective range accurately covers the target tissue area, meeting the requirements of non-invasive treatment for spatial positioning accuracy and magnetic field strength. In actual use, the rotational driving structure drives the iron plate and the fixed permanent magnet 2 to rotate around the vertical axis. The magnetization direction rotates with space, thereby generating a rotating magnetic field above the magnet with a direction that changes over time. The magnetic field strength in this region is sufficient to drive the magnetic material.

[0096] In animal clinical tumor treatment, cats or dogs can be placed in a natural lying position above the device, placing their abdominal target area within the coverage of the rotating magnetic field. After stereotactic localization of the target area, magnetic micro / nano drugs are injected, precisely targeting tumor cells. Under the influence of the rotating magnetic field, microscopic disturbances or mechanical destructive effects occur, thereby interfering with or even destroying the tumor cells, achieving the goal of non-invasive magnetic therapy. Furthermore, personalized treatment plans can be designed based on the individual pet's condition, employing variable-frequency micromagnetic tumor therapy to inhibit tumor cell growth, activate the immune response, and thus eliminate the tumor and suppress recurrence. For example, in the first stage (such as the tumor destruction stage), adjusting the rotation frequency to 900 rpm can maximize the elimination of residual tumor cells after surgery; this stage typically lasts for 5 days. In the second stage (such as the immune activation stage), adjusting the rotation frequency to 120 rpm can activate the systemic tumor immune response and inhibit tumor growth; this stage also typically lasts for 5 days. Immune activation refers to the induction of a systemic immune response in the body after physical disturbance promotes the release and presentation of tumor-associated antigens, thereby inhibiting residual or potential lesions.

[0097] Example 2

[0098] In this embodiment, the device is applied to the rehabilitation treatment of animal bones and joints. For example, for small dogs suffering from osteoarthritis, the animal can be placed in a natural lying position on the animal support plate 5, so that the affected joint area (such as the knee or hip joint) is within the intervention range of the rotating magnetic field. After injecting or implanting magnetic microparticles (such as magnetic hydrogel or magnetic microspheres), the rotating magnetic field generator is activated, and the magnetic material is driven to generate mild mechanical stimulation in the joint cavity or fracture healing area through magnetic field disturbance at low to medium frequency (such as 60 to 120 rpm).

[0099] This stimulation can promote local blood circulation, enhance osteoblast activity, accelerate cartilage repair, and reduce inflammatory responses, thereby achieving the effect of rehabilitation intervention. Compared with the high-frequency, strong magnetic disturbances used in tumor treatment, rehabilitation therapy focuses more on gentle, continuous magnetic field effects to avoid placing excessive burden on the repairing tissues.

[0100] It should be noted that in this patent application, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one" does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element. In this patent application, if it refers to performing an action according to an element, it means performing the action at least according to that element, including two cases: performing the action only according to that element, and performing the action according to that element and other elements. Expressions such as "multiple," "repeatedly," and "various" include two, two times, two kinds, and more than two, more than two times, and more than two kinds.

[0101] All documents mentioned in this application are considered to be incorporated in their entirety into the disclosure of this application so that they can serve as a basis for modifications if necessary. Furthermore, it should be understood that after reading the foregoing disclosure of this application, those skilled in the art can make various alterations or modifications to this application, and these equivalent forms also fall within the scope of protection claimed in this application.

Claims

1. A rotating magnetic field generating device, characterized by comprising: include: The magnetic field generating component includes a carrier substrate (1) and at least two permanent magnets (2) with fixed magnetization directions and spaced apart from each other on the carrier substrate (1); A rotary drive mechanism (3) is used to drive the magnetic field generating component to rotate around a vertical axis; The magnetic field generating component is positioned directly below the treatment area where the pet is placed to form a rotating magnetic field in the abdominal region of the pet, the direction of which changes over time, driving the magnetic material within the organelles delivered to the abdominal tumor cells of the pet to rotate.

2. The rotating magnetic field generating device according to claim 1, wherein The permanent magnets (2) are arranged symmetrically or in a ring around the axis of rotation. In a preferred embodiment, the plurality of permanent magnets (2) are cuboids, sectors, or circles. In a preferred embodiment, the number of permanent magnets (2) is 2, 4, 6 or 8.

3. The rotating magnetic field generating device according to claim 1, wherein The rotating magnetic field has a central disturbance region, which corresponds to the midline of the pet's abdomen.

4. The rotating magnetic field generating device according to claim 1, wherein The permanent magnet (2) includes a first permanent magnet (21) and a second permanent magnet (22), wherein the magnetization direction of the first permanent magnet (21) is along the positive direction of the vertical direction, and the magnetization direction of the second permanent magnet (22) is along the negative direction of the vertical direction. In a preferred embodiment, the distance between the first permanent magnet (21) and the second permanent magnet (22) is 1 cm to 10 cm; more preferably, the distance between the first permanent magnet (21) and the second permanent magnet (22) is 3 cm.

5. The rotating magnetic field generating device according to claim 1, wherein The rotating magnetic field is a centripetal rotating magnetic field in an approximately horizontal plane. In a preferred embodiment, the rotating magnetic field is a vector magnetic field whose direction changes with time in a horizontal plane, used to apply periodic orientation drive to magnetic materials in the abdominal region of an animal.

6. The rotating magnetic field generating device according to claim 1, wherein It also includes an outer casing (5) disposed around the periphery of the magnetic field generating component.

7. The rotating magnetic field generating device according to claim 6, wherein The outer shell (5) includes an animal support plate (5) disposed above the magnetic field generating component. The animal support plate (5) is a horizontal structure used to support the pet to be treated. The abdominal area of ​​the pet is within the range of magnetic field intervention.

8. The rotating magnetic field generating device as claimed in claim 7, characterized in that, A removable cover is provided above the animal support plate (5) to cover and limit the range of movement of small animals during treatment. In a preferred embodiment, the inner effective volume of the housing is between 200 cm 3 and 800 cm 3 for small pets with a length of 5 cm to 12 cm of the aptitude. In a preferred embodiment, the cover material is a transparent or translucent material. In a preferred embodiment, an animal restraint device is also provided on the animal support plate (5) for restricting the position of the head and limbs when the pet is awake, so as to stabilize the pet's posture during treatment. In a preferred embodiment, the animal restraint device includes multiple flexible straps, head loops, or adjustable supports for securing the animal's limbs, torso, and head respectively.

9. The rotating magnetic field generating device according to any of claims 1-8, characterized in that, The rotation frequency of the rotary drive mechanism (3) can be adjusted from 0 rpm to 1000 rpm.

10. A control method of a rotating magnetic field generating apparatus, characterized by, Includes the following steps: a) Provides a device as described in any one of claims 1-9, for placing a pet whose body has been delivered magnetic material onto the device; b) Control the operation of the device to cause the magnetic field generating component to generate a rotating magnetic field whose direction changes with time; c) The magnetic material is disturbed by the rotating magnetic field. In a preferred embodiment, step a) of placing the pet, on which the magnetic material has been delivered, onto the device further includes placing the pet in a natural lying position on the animal support plate (5) of the device, such that the abdominal region of the pet is within the range of the interference of the rotating magnetic field.

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