Cell mixing sampler

Abstract

The utility model relates to the technical field of biology, in particular to a cell mixing sampler which comprises a culture dish, a support is arranged at the top of the culture dish, a salvage mechanism is arranged on the front face of the support and can continuously drive a sampling barrel to sample cells in the culture dish, and the sampling barrel is arranged at the bottom of the salvage mechanism through a cylinder. The cylinder is fixedly connected to the top of the sampling barrel and provides supporting force for the sampling barrel, the stirring mechanism drives a protruding block and a movable rod to rotate through rotation of a wing plate, and through mutual cooperation of internal components of the fishing mechanism, the sampling barrel can replace manual work to conduct continuous sampling, so that the time spent on the sampling procedure by researchers is saved, and the sampling efficiency is improved. The research efficiency is improved, through mutual cooperation of components in the stirring mechanism, a sampling barrel drives fan blades to rotate to stir and mix a culture solution in the culture dish and various types of cells while sampling in the culture dish, so that the various types of cells in the culture dish are distributed more uniformly.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to a cell mixing sampler. Background Art

[0002] There is no unified definition of cell. The more common statement is that cells are the basic structural and functional units of organisms. It is known that all organisms except viruses are composed of cells, but the life activities of viruses must also be manifested in cells. Generally speaking, most microorganisms such as bacteria and protozoa are composed of one cell, that is, single-cell organisms, while higher plants and higher animals are multicellular organisms. Cells can be divided into two categories: prokaryotic cells and eukaryotic cells, but some people have proposed that they should be divided into three categories, that is, archaeal cells that originally belonged to prokaryotic cells are separated as a category parallel to them. The discipline that studies cells is called cell biology. The cell body is extremely small and can only be seen under a microscope. It has a variety of shapes. It is mainly composed of a nucleus and cytoplasm, with a cell membrane on the surface. Higher plants have a cell wall outside the cell membrane, plastids are often in the cytoplasm, chloroplasts and vacuoles are in the body, and there are mitochondria. Animal cells have no cell walls, centrosomes are often in the cytoplasm, but higher plant cells do not have centrosomes. Cells have functions such as movement, nutrition and reproduction.

[0003] After searching, the Chinese patent publication number CN210465018U discloses a sampler for drawing a first liquid from a first liquid storage device; the sampler includes a sampling body, a capillary pipette and a connector; the capillary pipette is open at both ends and arranged along the longitudinal direction; the connector includes a spacer and a capillary pipette assembly; one end of the spacer is connected to the sampling body, and the other end is connected to one end of the capillary pipette assembly, and the other end of the capillary pipette assembly is connected to the side wall of the capillary pipette. The above patent has the following shortcomings: although the patent can extract cells, the amount of cell sampling each time is not enough to support the amount required for research and observation, so multiple sampling is required, and the patent does not set up a mechanism that can replace manual continuous sampling, so researchers need to spend a lot of time on sampling, which reduces research efficiency. In view of this, we propose a cell mixing sampler. Utility Model Content

[0004] The purpose of the utility model is to provide a cell mixing sampler to solve the problems raised in the above background technology.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A cell mixing sampler comprises a culture dish, the top of which is provided with a bracket, the front of which is provided with a salvage mechanism, which can continuously drive a sampling barrel to sample cells in the culture dish, the sampling barrel is arranged at the bottom of the salvage mechanism through a cylinder, the cylinder is fixedly connected to the top of the sampling barrel to provide support for the sampling barrel, and the stirring mechanism is arranged at the bottom of the salvage mechanism to mix various cells inside the culture dish.

[0007] Preferably, the salvage mechanism includes a motor, which is fixedly connected to the back side of the bracket, and the front output end of the motor rotates and passes through the front and rear ends of the bracket and is fixedly connected to a transmission shaft, the front end of the transmission shaft is fixedly connected to a wing plate, the middle part of the transmission shaft is rotatably connected to a movable rod, and the front side of the movable rod is fixedly connected to a protrusion, which is arranged at the bottom of the wing plate, and the rotation of the wing plate drives the protrusion and the movable rod to rotate.

[0008] Preferably, the front side of the movable rod is hinged with a movable column through a rotating shaft, the bottom of the movable column is hinged with a sliding rod, the front side of the bracket is fixedly connected with a sliding groove, the sliding rod is slidably connected inside the sliding groove, and the cylinder is rotatably connected to the bottom of the sliding rod, and the sliding rod is limited by setting the sliding groove.

[0009] Preferably, the stirring mechanism includes a fixed block, which is connected to the bottom of the bracket, a threaded pick is fixedly connected to the front side of the fixed block, a threaded groove is provided on the outer wall of the cylinder, and the front end of the threaded pick is threadedly connected to the threaded groove. The threaded pick and the threaded groove are arranged to drive the cylinder to rotate when it moves up and down.

[0010] Preferably, ten fan blades for assisting cell mixing are fixedly connected to the side of the sampling barrel.

[0011] Preferably, a filtering hole for filtering cells is provided at the bottom of the sampling bucket.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] 1. Through the cooperation of the internal components of the salvage mechanism, the sampling bucket can replace manual continuous sampling, thereby saving the time spent by researchers on the sampling process and improving research efficiency.

[0014] 2. Through the cooperation of the internal components of the stirring mechanism, the sampling bucket can drive the fan blades to rotate while sampling in the culture dish to stir and mix the culture fluid and various types of cells in the culture dish, so that the distribution of various types of cells in the culture dish is more uniform. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 It is a bottom cross-sectional view of the utility model;

[0017] Figure 3 It is an enlarged view of the A area in the utility model;

[0018] Figure 4 It is a schematic diagram of the stirring mechanism area in the utility model.

[0019] In the figure: 1. culture dish; 2. bracket; 3. sampling bucket; 4. salvaging mechanism; 5. stirring mechanism; 6. cylinder; 41. motor; 42. transmission shaft; 43. wing plate; 44. movable rod; 45. bump; 46. movable column; 47. slide groove; 48. slide rod; 51. fixed block; 52. threaded pick; 53. threaded groove; 54. fan blade. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] In the prior art, Chinese Patent Publication No. CN210465018U discloses a sampler.

[0022] The inventor found that although this patent can extract cells, the amount of cells sampled each time is not enough to support the amount required for research observation, so multiple sampling is required. However, this patent does not have a mechanism to replace manual continuous sampling, so researchers need to spend a lot of time on sampling, which reduces research efficiency.

[0023] like Figure 1-4 As shown, a cell mixing sampler includes a culture dish 1, a bracket 2 is arranged on the top of the culture dish 1, a salvage mechanism 4 is arranged on the front of the bracket 2, and can continuously drive the sampling barrel 3 to sample the cells in the culture dish 1, the sampling barrel 3 is arranged at the bottom of the salvage mechanism 4 through a cylinder 6, the cylinder 6 is fixedly connected to the top of the sampling barrel 3 to provide support for the sampling barrel 3, the stirring mechanism 5 is arranged at the bottom of the salvage mechanism 4 to mix various cells inside the culture dish 1, ten fan blades 54 for assisting cell mixing are fixedly connected to the side of the sampling barrel 3, and a filtering hole for filtering cells is opened at the bottom of the sampling barrel 3.

[0024] In order to continuously sample the cells in the culture dish 1, the salvage mechanism 4 includes a motor 41, which is fixedly connected to the back side of the bracket 2. The front output end of the motor 41 rotates and passes through the front and rear ends of the bracket 2 and is fixedly connected to a transmission shaft 42. The front end of the transmission shaft 42 is fixedly connected to a wing plate 43. The middle part of the transmission shaft 42 is rotatably connected to a movable rod 44. The front side of the movable rod 44 is fixedly connected to a protrusion 45. The protrusion 45 is arranged at the bottom of the wing plate 43. The rotation of the wing plate 43 drives the protrusion 45 and the movable rod 44 to rotate. The front side of the movable rod 44 is hinged with a movable column 46 through a rotating shaft. The bottom of the movable column 46 is hinged with a sliding rod 48. The front side of the bracket 2 is fixedly connected with a slide groove 47. The sliding rod 48 is slidably connected to the inside of the slide groove 47. The cylinder 6 is rotatably connected to the bottom of the sliding rod 48. The sliding groove 47 is set to limit the up and down movement of the sliding rod 48, so that the sampling bucket 3 can continuously sample the cells in the culture dish 1.

[0025] Furthermore, in order to make the distribution of various types of cells in the culture dish 1 more uniform, the stirring mechanism 5 includes a fixed block 51, which is connected to the bottom of the bracket 2, and a threaded pick 52 is fixedly connected to the front of the fixed block 51. A threaded groove 53 is provided on the outer wall of the cylinder 6, and the front end of the threaded pick 52 is threadedly connected to the threaded groove 53. By arranging the threaded pick 52 and the threaded groove 53, the cylinder 6 is driven to rotate when it moves up and down, thereby driving the distribution of various types of cells in the culture dish 1 to be more uniform through the rotation of the fan blades 54.

[0026] The working principle of the utility model is as follows:

[0027] Turn on the motor 41 to drive the transmission shaft 42 to rotate, and the rotation of the transmission shaft 42 drives the wing plate 43 to rotate. After the wing plate 43 rotates and contacts the protrusion 45, it drives the protrusion 45 and the movable rod 44 to rotate. The rotation of the movable rod 44 drives the movable column 46 to rotate. The rotation of the movable column 46 drives the slide bar 48 to move up and down in the slide groove 47. The up and down movement of the slide bar 48 drives the cylinder 6 and the sampling bucket 3 to move up and down. The sampling bucket 3 moves up and down to continuously sample the cells in the culture dish 1. While the cylinder 6 moves up and down, it is driven by the threaded paddle 52 to rotate. The rotation of the cylinder 6 drives the sampling bucket 3 and the fan blades 54 to rotate. The rotation of the fan blades 54 drives the culture fluid and various cells in the culture dish 1 to flow, and makes the distribution of various cells in the culture dish 1 more uniform.

[0028] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the utility model and are not used to limit the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection of the utility model is defined by the attached claims and their equivalents.

Claims

1. A cell mixing sampler, comprising a culture dish (1), characterized in that: A support (2) is provided on the top of the culture dish (1); The front side of the support (2) is provided with a salvaging mechanism (4) which can continuously drive the sampling bucket (3) to sample the cells in the culture dish (1); The sampling bucket (3) is arranged at the bottom of the salvaging mechanism (4) via a cylinder (6); The cylinder (6) is fixedly connected to the top of the sampling barrel (3) to provide support for the sampling barrel (3); The stirring mechanism (5) is arranged at the bottom of the salvaging mechanism (4) to mix the various cells inside the culture dish (1).

2. A cell mixing sampler according to claim 1, characterized in that: The salvaging mechanism (4) comprises a motor (41), wherein the motor (41) is fixedly connected to the back side of the bracket (2), the front output end of the motor (41) rotatably penetrates the front and rear ends of the bracket (2) and is fixedly connected to a transmission shaft (42), the front end of the transmission shaft (42) is fixedly connected to a wing plate (43), the middle part of the transmission shaft (42) is rotatably connected to a movable rod (44), the front side of the movable rod (44) is fixedly connected to a protrusion (45), and the protrusion (45) is arranged at the bottom of the wing plate (43).

3. A cell mixing sampler according to claim 2, characterized in that: The front of the movable rod (44) is hinged with a movable column (46) through a rotating shaft, and the bottom of the movable column (46) is hinged with a sliding rod (48). The front of the bracket (2) is fixedly connected with a sliding groove (47), and the sliding rod (48) is slidably connected inside the sliding groove (47). The cylinder (6) is rotatably connected to the bottom of the sliding rod (48).

4. A cell mixing sampler according to claim 3, characterized in that: The stirring mechanism (5) comprises a fixed block (51), the fixed block (51) is connected to the bottom of the bracket (2), a threaded pick (52) is fixedly connected to the front side of the fixed block (51), a threaded groove (53) is formed on the outer wall of the cylinder (6), and the front end of the threaded pick (52) is threadedly connected to the threaded groove (53).

5. A cell mixing sampler according to claim 4, characterized in that: Ten fan blades (54) for assisting cell mixing are fixedly connected to the side of the sampling barrel (3).

6. A cell mixing sampler according to claim 5, characterized in that: The bottom of the sampling barrel (3) is provided with a filtering hole for filtering cells.

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