Kit

Abstract

The utility model relates to the technical field of detection kits, in particular to a kit. The kit comprises a reagent storage part and a reaction cavity part, the reaction cavity part comprises a first cavity, a second cavity and a third cavity, the first cavity is used for receiving a first reagent and a sample, the second cavity is communicated with the first cavity, the third cavity is communicated with the first cavity, and the first cavity is used for receiving a second reagent and a sample. The first chamber is partially communicated with the second chamber, the first chamber is partially communicated with the third chamber, and the reaction cavity part can rotate to enable the first reagent, the second reagent and the sample to move between the first chamber and the second chamber and between the first chamber and the third chamber; the reagent storage part comprises a first reagent accommodating cavity for storing a first reagent and a second reagent accommodating cavity for storing a second reagent, and the reaction cavity part is provided with a first puncture needle and a second puncture needle which are respectively opposite to the first reagent accommodating cavity and the second reagent accommodating cavity.

Description

Technical Field

[0001] The utility model relates to the technical field of detection kits, and in particular to a kit. Background Art

[0002] POCT is a sub - industry of in vitro diagnostic devices (IVD). With the advantages of convenience and rapidity, it can achieve rapid diagnostic results beside patients. At present, POCT products have been widely used in hospitals, clinics and patients' homes, and can detect the vast majority of routine clinical indicators. POCT has been widely used in ICUs, surgeries, emergency departments, clinics and patients' homes. This product is a POCT product, and currently mainly measures specific proteins. The utility model changes the traditional liquid - adding and sampling modes, has extremely low requirements for users, and facilitates the use of customers.

[0003] Before most semi - automatic POCT products on the market are measured currently, it is necessary to use a pipette to add liquid to the test box in advance and separately use a pipette to sample and add the sample to the test box. After the reaction is completed, it is necessary to manually place the test box in the test position and then add another reagent, and then click the test button on the instrument to measure. The process is very cumbersome. The Chinese invention patent CN200810009127.4 of the South Korean company InFuPia Co., Ltd. provides a reaction box for a glycosylated hemoglobin detector and a detection method using the reaction box. The method it uses only has the chromatography method to test glycosylated hemoglobin. The sampling device and the reagent package are integrated, with a relatively large volume, and it is easy to bend and for foreign objects to enter the sampling port, which also increases the production cost. However, the products of our company have optimized these disadvantages, are more user - friendly, and also save costs. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a brand - new kit aiming at problems in the prior art such as the relatively large volume of the sampling device, easy bending and entry of foreign objects, and single applicable detection method. It changes the traditional liquid - adding mode and sampling method, integrates liquid - adding and sampling, realizes that the sampling needle can be folded and stored through the structure, automatically pierces the reagent seal, greatly reduces the packaging volume, and facilitates the use of customers; the test box integrates the chromatography method and the turbidimetry method, greatly increasing the applicable scope of test items. To achieve the above - mentioned purpose, the technical solution adopted by the utility model is as follows.

[0005] A kit includes a reagent storage component and a reaction chamber component. The reaction chamber component includes a first chamber, a second chamber, and a third chamber. The first chamber is used to receive a first reagent and a sample, and provides a reaction site for the first reagent and the sample. The second chamber communicates with the first chamber and is used to receive a second reagent. The third chamber communicates with the first chamber and is used to allow the reaction solution in the first chamber to flow into the third chamber. The first chamber is locally connected to the second chamber and the first chamber is locally connected to the third chamber respectively. The reaction chamber component can be rotated so that the first reagent, the second reagent, and the sample move between the first chamber and the second chamber, and the first chamber and the third chamber.

[0006] The reagent storage component includes a first reagent accommodation chamber for storing the first reagent and a second reagent accommodation chamber for storing the second reagent. The reaction chamber component is provided with a first puncturing needle and a second puncturing needle respectively opposite to the first reagent accommodation chamber and the second reagent accommodation chamber. The reagent storage component can be inserted into the reaction chamber component. When the reagent storage component is inserted into the reaction chamber component, the first puncturing needle and the second puncturing needle puncture the sealing parts of the first reagent accommodation chamber and the second reagent accommodation chamber and insert into the first reagent accommodation chamber and the second reagent accommodation chamber, so that the first reagent and the second reagent flow into the first chamber and the second chamber respectively.

[0007] Further, the first puncturing needle and the second puncturing needle are of a hollow structure to allow the first reagent and the second reagent to flow out smoothly.

[0008] Further, the reagent storage component further includes a sampling part. The sampling part includes a sampling arm and a sampling needle provided at the end of the sampling arm. The sampling needle can sample by the principle of siphon. The sampling arm is located on the side of the reagent storage component and can rotate 180° along the insertion direction of the reagent storage component.

[0009] Further, the first chamber is provided with a first detection port, the third chamber is provided with a second detection port, and the third chamber is divided into a detection chamber and a waste liquid chamber through the second detection port. The detection chamber communicates with the second chamber.

[0010] Further, the reaction chamber component further includes a fourth chamber. The fourth chamber communicates with the waste liquid chamber and is used to discharge the air in the waste liquid chamber into the fourth chamber.

[0011] Further, an absorbent material is provided in the waste liquid chamber.

[0012] Further, the reaction chamber component is provided with a card slot, and the reagent storage component is provided with a clamping part for locking with the reaction chamber component.

[0013] Further, the reaction chamber component is provided with a positioning rod, and the reagent storage component is provided with a positioning groove. When the reagent storage component is inserted into the reaction chamber component, the positioning cylinder is inserted into the positioning groove.

[0014] Compared with the prior art, the utility model has the following beneficial effects:

[0015] 1. You only need to use the sampling device that comes with the reagent package to take a sample and then insert it into the test box. The rest of the process is completed automatically by the instrument. No pipette is required to complete the liquid addition and sampling operations, which greatly simplifies the measurement process and facilitates customer use.

[0016] 2. It can be used for projects based on both nephelometry and chromatography methodologies, with a wider testing range.

[0017] 3. No pollution, all the liquid enters the absorbent sponge after the test is completed.

[0018] 4. It integrates liquid addition and sampling in one unit. The sampling needle can be folded and stored through the structure, and the reagent seal can be automatically punctured, which greatly reduces the packaging volume and has low cost.

[0019] 5. It can automatically puncture and add liquid, which is more user-friendly. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of the present application. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the drawings:

[0021] Figure 1 It is a schematic diagram of the structure of the test kit of Example 1 of the utility model;

[0022] Figure 2 This is another schematic diagram of the test kit structure of Example 1 of the utility model;

[0023] Figure 3 This is another schematic diagram of the test kit structure of Example 1 of the utility model;

[0024] Figure 4 It is a schematic diagram of the test kit of Example 1 of the utility model being rotated at different angles for testing.

[0025] Figure identification: 1-first reagent holding chamber, 2-second reagent holding chamber, 3-sampling arm, 4-sampling needle, 5-puncture needle, 6-first test port, 7-water-absorbing material, 8-second test port, 9-second chamber, 10-first chamber, 11-third chamber, 12-fourth chamber, 13-clamping part, 14-slot, 15-positioning slot, 16-positioning rod. DETAILED DESCRIPTION

[0026] To make the objectives, technical solutions and advantages of the present utility model more clear and understandable, the present utility model will be further described in detail below in conjunction with embodiments and the accompanying drawings. The illustrative embodiments and descriptions of the present utility model are only used to explain the present utility model and do not limit the present utility model.

[0027] It should be noted that when an element is referred to as "fixed to" or "disposed on" another element, it can be directly on the other element or there may be an intermediate element at the same time. When an element is referred to as "connected to" another element, it can be directly connected to the other element or there may be an intermediate element at the same time. When an element is referred to as "provided with" another element, it can be provided on the surface or inside of the element.

[0028] In view of the problems in the prior art that the sampling device is relatively large in volume, prone to bending and entering the sample, and the applicable detection methods are single, etc., the present utility model provides a brand-new reagent kit, which changes the traditional liquid addition mode and sampling method, integrates liquid addition and sampling, and realizes that the sampling needle can be folded and stored through the structure, automatically punctures the reagent seal, greatly reduces the packaging volume, and is convenient for customers to use; the test kit integrates chromatography and turbidimetry, greatly increasing the applicable range of test items. The following describes the present utility model with specific embodiments.

[0029] Embodiment 1

[0030] Please refer to Figures 1 to 3 , Embodiment 1 provides a reagent kit, which includes a reagent storage component and a reaction cavity component. The reaction cavity component includes a first chamber 10, a second chamber 9, and a third chamber 11. The first chamber 10 is used to receive a first reagent and a sample, and provides a reaction site for the first reagent and the sample. The second chamber 9 communicates with the first chamber 10 and is used to receive a second reagent. The third chamber 11 communicates with the first chamber 10 and is used to flow the reaction liquid in the first chamber 10 into the third chamber 11. The first chamber 10 is locally communicated with the second chamber 9 and the first chamber 10 is locally communicated with the third chamber 11 in a common cutting plane direction. The reaction cavity component can be rotated to move the first reagent, the second reagent and the sample between the first chamber 10 and the second chamber 9, and the first chamber 10 and the third chamber 11; as Figure 4 shown.

[0031] The reagent storage component includes a first reagent accommodating chamber 1 for storing a first reagent and a second reagent accommodating chamber 2 for storing a second reagent. The reaction chamber component is provided with a first puncturing needle and a second puncturing needle respectively opposite to the first reagent accommodating chamber 1 and the second reagent accommodating chamber 2. The reagent storage component can be inserted into the reaction chamber component. When the reagent storage component is inserted into the reaction chamber component, the first puncturing needle and the second puncturing needle puncture the sealing parts of the first reagent accommodating chamber 1 and the second reagent accommodating chamber 2 and insert into the first reagent accommodating chamber 1 and the second reagent accommodating chamber 2, so that the first reagent and the second reagent flow into the first chamber 10 and the second chamber 9 respectively.

[0032] In the kit of this embodiment, the first chamber 10 and the second chamber 9, and the first chamber 10 and the third chamber 11 are not completely connected, nor are they completely separated, but are partially connected. It can be understood that the connecting part of the two chambers that need to be connected is on the common section plane of the two chambers. In this way, it not only ensures that the liquids in each chamber will not be mixed with each other, but also can be smoothly mixed when the liquids in the two chambers need to be mixed. The liquid here can be a certain reagent, or a mixed liquid after mixing or chemical reaction of multiple reagents, etc.

[0033] For the convenience of detection, the first chamber 10 is provided with a first detection port, the third chamber 11 is provided with a second detection port, and the third chamber 11 is separated into a detection chamber and a waste liquid chamber through the second detection port, and the detection chamber is communicated with the second chamber 9.

[0034] The reaction chamber component is provided with a card slot 14, and the reagent storage component is provided with a clamping part 13 for locking with the reaction chamber component. The reaction chamber component is provided with a positioning rod 16, and the reagent storage component is provided with a positioning groove 15. When the reagent storage component is inserted into the reaction chamber component, the positioning cylinder is inserted into the positioning groove 15.

[0035] In order to prevent the puncturing needle 5 from causing partial or complete blockage of the puncture port, which is not conducive to the outflow of the reagent. In some embodiments, the first puncturing needle and the second puncturing needle are of a hollow structure, which allows the first reagent and the second reagent to flow out smoothly. When the reagent flows out from the puncture port, it can also flow out from the hollow hole in the middle of the puncturing needle 5, saving time.

[0036] Furthermore, in order to improve the storage convenience and use convenience of the kit, the reagent storage component further includes a sampling part. The sampling part includes a sampling arm 3 and a sampling needle 4 provided at the end of the sampling arm 3. The sampling needle 4 can sample by the siphon principle. The sampling arm 3 is located on the side of the reagent storage component and can rotate 180° along the insertion direction of the reagent storage component.

[0037] When not in use, the sampling arm 3 can be rotated so that the sampling needle 4 faces upward, which is convenient for storage. When in use, the sampling arm 3 is rotated so that the sampling needle 4 faces vertically downward. As shown in Figure 1 , the sampling needle 4 is brought close to the sample, and sampling is carried out by the siphon principle. After sampling is completed, it is inserted into the reaction cavity component. The reaction cavity component locks the reagent pack through an inverted buckling device. After the test is completed, it is disposed of as medical waste together. The reaction cavity component forms different flow channels through an intermediate partition to separate the reagents. The puncturing needle 5 includes a first puncturing needle and a second puncturing needle. The first puncturing needle punctures the sealing films of the first reagent accommodating cavity 1 and the second reagent accommodating cavity 2. The first reagent flows into the first chamber 10 through the hole in the middle of the first puncturing needle and is mixed with the sample. The second reagent flows into the second chamber 9 through the hole in the middle of the second puncturing needle. After shaking the reaction cavity component to make the first reagent and the sample react completely, the second reagent is added to the first chamber 10 by rotation and mixed. If the instrument determines that turbidimetry test is required, the test will be directly carried out through the optical path at the first test port 6. After the test is completed, the reaction cavity component is rotated to drain the waste liquid into the third chamber 11. An absorbent material 7 is provided in the waste liquid chamber of the third chamber 11, which can be any material with strong water absorption such as sponge, cotton, paper, gel, etc. If the instrument determines that chromatography test is required, the reaction cavity component will be rotated to make the reacted reagent flow through the second test port 8 into the absorbent cotton in the third chamber 11, so as to leave the microspheres used for the test to fill the second test port 8. The instrument judges the measured value of the sample according to the different degrees of reflection of the microspheres.

[0038] Furthermore, when the waste liquid flows into the waste liquid chamber, if the waste liquid chamber is sealed, the discharge of the waste liquid will inevitably cause the air in the waste liquid chamber to be squeezed, and the waste liquid is mostly various chemical substances after chemical reactions and may continue to react. This phenomenon will be more serious for waste liquids that generate gas. In order to prevent the air pressure in the waste liquid chamber from rising and causing the waste liquid to not be discharged, the reaction cavity component further includes a fourth chamber 12, and the fourth chamber 12 is communicated with the waste liquid chamber for discharging the air in the waste liquid chamber into the fourth chamber 12.

[0039] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "rear", "left", "right", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0040] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than limiting it. Although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. These modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A kit, characterized in that, It includes a reagent storage component and a reaction chamber component. The reaction chamber component includes a first chamber, a second chamber, and a third chamber. The first chamber is used to receive a first reagent and a sample, and provides a reaction site for the first reagent and the sample. The second chamber communicates with the first chamber and is used to receive a second reagent. The third chamber communicates with the first chamber and is used to allow the reaction liquid in the first chamber to flow into the third chamber. The first chamber is locally connected to the second chamber and the first chamber is locally connected to the third chamber respectively. The reaction chamber component can be rotated to enable the first reagent, the second reagent, and the sample to move between the first chamber and the second chamber, and between the first chamber and the third chamber; The reagent storage component includes a first reagent receiving cavity for storing the first reagent and a second reagent receiving cavity for storing the second reagent. The reaction chamber component is provided with a first puncturing needle and a second puncturing needle respectively opposite to the first reagent receiving cavity and the second reagent receiving cavity. The reagent storage component can be inserted into the reaction chamber component. When the reagent storage component is inserted into the reaction chamber component, the first puncturing needle and the second puncturing needle puncture the sealing parts of the first reagent receiving cavity and the second reagent receiving cavity and insert into the first reagent receiving cavity and the second reagent receiving cavity, so that the first reagent and the second reagent flow into the first chamber and the second chamber respectively.

2. A kit according to claim 1, characterized in that, The first puncturing needle and the second puncturing needle are of a hollow structure to allow the first reagent and the second reagent to flow out smoothly.

3. A kit according to claim 2, characterized in that The reagent storage component further includes a sampling part. The sampling part includes a sampling arm and a sampling needle provided at the end of the sampling arm. The sampling needle can sample by the siphon principle. The sampling arm is located on the side of the reagent storage component and can rotate 180° along the insertion direction of the reagent storage component.

4. A kit according to claim 3, characterized in that, The first chamber is provided with a first detection port, the third chamber is provided with a second detection port, and the third chamber is divided into a detection chamber and a waste liquid chamber through the second detection port. The detection chamber communicates with the second chamber.

5. A kit according to claim 4, wherein The reaction chamber component further includes a fourth chamber. The fourth chamber communicates with the waste liquid chamber and is used to discharge the air in the waste liquid chamber into the fourth chamber.

6. A kit according to claim 5, wherein An absorbent material is provided in the waste liquid chamber.

7. A kit according to claim 1, characterized in that, The reaction chamber component is provided with a clamping groove, and the reagent storage component is provided with a clamping part for locking with the reaction chamber component.

8. A kit according to claim 1, wherein The reaction chamber component is provided with a positioning rod, and the reagent storage component is provided with a positioning groove. When the reagent storage component is inserted into the reaction chamber component, the positioning cylinder is inserted into the positioning groove.

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