Bone tumor model construction device

Abstract

The utility model provides a bone tumor model building device. The bone tumor model building device is composed of a bone fixing unit, a combined connecting frame and a modeling depth control assembly. A bone clamp of the bone fixing unit is opened and closed through a connecting rod to stably clamp the bone, and a protective shell is used for protection and auxiliary control. And the combined connecting frame is connected with the positioning bone fixing unit and guides the operating rod. The molding depth control assembly accurately controls the punching depth, after punching, organoids (such as tumor cell clusters and the like) can be accurately implanted into specific positions of bone materials, the bone tumor growth environment is simulated more truly, a key pathological basis is provided for model construction, and the molding accuracy and reliability are ensured. The device improves the accuracy and stability of bone model construction, can adapt to different bone materials, improves the uniformity of a bone tumor model, meets the requirements of various experimental scenes such as bone disease research and treatment method development, and powerfully promotes the development of related bone research.

Description

Technical Field

[0001] The utility model relates to the technical field of bone model construction, in particular to a bone tumor model construction device. Background Art

[0002] The description of the background technology is merely a general description for facilitating understanding of the content of the present invention and does not constitute any limitation to the present invention.

[0003] In the field of bone tissue engineering and bone-related research, bone model construction is an important means to deeply study bone physiology and pathology mechanisms and develop new treatment methods. However, existing bone model construction devices have many shortcomings.

[0004] Conventional bone modeling devices offer limited stability when securing bone material or tissue. Bone material can easily shift during manipulation, a significant problem for experiments requiring high precision. For example, in bone tissue engineering, when studying cell growth on a scaffold, even the slightest movement of the scaffold can lead to significant deviations in experimental results.

[0005] Existing devices lack precise control capabilities for modeling operations, such as drilling and drug injection. Drilling is difficult to accurately drill holes in the intended bone area, and the depth of the holes cannot be precisely controlled. During drug injection, drugs cannot be accurately delivered to the target location, making the constructed bone models difficult to meet the requirements of detailed research.

[0006] Furthermore, existing bone modeling devices lack structural flexibility, making it difficult to adapt to different bone materials, shapes, and sizes. Furthermore, their versatility is limited, making them unable to simultaneously meet multiple operational requirements, such as ensuring the accuracy and stability of subsequent operations such as drilling and injection while simultaneously performing fixation.

[0007] Based on the above problems, there is an urgent need to design a new bone tumor model construction device that can achieve stable fixation of bone materials or bone tissues, accurately control various operations in the modeling process (such as drilling depth, etc.), improve the accuracy and stability of bone model construction, and be able to adapt to the various needs of different bone research experimental scenarios. At the same time, after drilling, the organoids can be precisely implanted into specific positions of the bone material, more realistically simulating the growth environment of bone tumors, providing a key pathological basis for model construction, ensuring the accuracy and reliability of modeling, and thus promoting the development of bone-related research in terms of accuracy and effectiveness. Utility Model Content

[0008] To address the problems existing in the prior art, the present invention provides a bone tumor model construction device. Its unique bone fixation unit securely clamps the bone material through a bone clamp structure, addressing issues of unstable fixation and easy displacement. A protective shell precisely controls the bone clamp and protects the internal structure to avoid interference. A combined connection frame precisely connects the positioning components and provides good guidance for the operating rod, overcoming the shortcomings of traditional devices with inaccurate connection positioning and poor guidance. The modeling depth control assembly utilizes the control component at the top of the operating rod, a scale mark, and a positioning washer to coordinately and precisely control the drilling depth. Through the coordinated operation of these components, the accuracy, stability, and versatility of the device in bone model construction are comprehensively improved, adapting to a variety of bone materials and experimental needs, promoting the development of bone-related research, and having broad application prospects.

[0009] In order to achieve the above purpose, the present invention adopts the following scheme:

[0010] On the one hand, the utility model provides a bone tumor model construction device, comprising a bone fixation unit, a combined connection frame, and a modeling depth control component, wherein the bone fixation unit, the combined connection frame, and the modeling depth control component are combined into a detachable integrated structure;

[0011] The bone fixation unit is used to achieve a stable clamping of bone material or bone tissue;

[0012] The combined connection frame is used to realize the connection and positioning of the bone fixation unit and to guide the modeling depth control component;

[0013] The molding depth control component is used to control the punching depth during the molding process.

[0014] In some embodiments, the present invention provides a novel bone tumor model construction device. The bone clamp structure (including a clamping rod, clamping arms, connecting rods, etc.) and the protective shell structure (including positioning screws, rotating shafts, etc.) in the bone fixation unit securely clamp bone material or bone tissue and precisely control the opening and closing of the bone clamp. The "mountain"-shaped combined frame structure (including a sleeve, guide sleeve, and connecting crossbeam) in the combined connecting frame connects and positions the bone fixation unit and guides the operating rod. The operating rod, the top control component of the operating rod, and the positioning washer in the modeling depth control assembly precisely control the drilling depth. These structures work together to improve the accuracy, stability, and versatility of bone model construction, meeting the needs of different bone research experimental scenarios.

[0015] Furthermore, the bone fixation unit includes a clamping structure, which includes a bone clamp, a protective shell and a rotating shaft. The bone clamp includes a clamping rod, a first clamping arm, a second clamping arm, a first connecting rod and a second connecting rod. The first connecting rod connects the clamping rod and the first clamping arm, and the second connecting rod connects the clamping rod and the second clamping arm, which is used to convert the linear motion of the clamping rod into the rotational motion of the clamping arm to realize the opening and closing of the bone clamp, thereby firmly clamping the bone material or bone tissue.

[0016] Furthermore, the protective shell is provided with a positioning screw and a rotating shaft, and the rotating shaft is located in the middle of the first clamp arm or the second clamp arm, so that the bone clamp is detachably connected to the protective shell. The positioning screw is used to determine the initial state of the bone clamp and serves as a reference point when the bone clamp is closed, and the degree of opening and closing of the bone clamp is controlled by the positional relationship with the clamping rod.

[0017] Furthermore, when the clamping rod is in the initial position, the first clamping arm and the second clamping arm remain in an open state, which facilitates the placement of bone material or bone tissue between the first clamping arm and the second clamping arm; when an external force is applied to the clamping rod to move it downward, the downward movement of the clamping rod drives the first clamping arm and the second clamping arm to rotate around the rotating shaft, so that they gradually close until the bone clamp tightly clamps the bone material or bone tissue, providing a reliable fixing foundation for subsequent modeling operations.

[0018] Furthermore, when the clamping rod is in the initial position, the bottom end of the clamping rod is flush with the positioning screw on the protective shell; when an external force is applied to the clamping rod to move it downward, the bottom of the clamping rod is lower than the positioning screw.

[0019] In some embodiments, in the initial state, the clamping rod of the bone clamp is in a specific position, that is, flush with the positioning screw on the upper part of the protective shell. At this time, supported by the rotating shaft, the clamping arms remain naturally open, which makes it convenient to place bone material or bone tissue between the clamping arms. When a clamping operation is required, an external force is applied to move the clamping rod downward. Since the clamping rod and the clamping arm are connected by a connecting rod, and the two ends of the connecting rod are respectively connected to the clamping rod and the clamping arm in a rotatable manner, this connection method constitutes a special connecting rod mechanism. Taking one of the clamping arms as an example, when the clamping rod moves downward, one end of the connecting rod connected to the clamping rod also drops. Since the length of the connecting rod is fixed and the other end can only rotate around the connection point, this causes the end to move upward, thereby prompting the clamping arms to rotate inward and close around the rotating shaft in the middle. Since the two clamping arms are structurally symmetrical and connected in the same way, they will rotate inward and close at the same time to achieve clamping of the bone material or bone tissue. During this process, the protective shell plays multiple roles. It not only protects the internal structures of the bone clamp, such as the rotating shaft and connecting rod, from interference or damage from external factors, but also the positioning screws on the protective shell accurately determine the initial opening state of the bone clamp and serve as an important reference point when the bone clamp closes. When the clamping rod moves down to a certain degree (the bottom is a certain distance below the positioning screw), the bone clamp reaches the predetermined closing degree, thus achieving precise control of the opening and closing degree of the bone clamp. In addition, the protective shell, with a central connection hole and a concave guide groove on the top that precisely fits the clamping rod, ensures that the clamping rod can move smoothly and fluidly in the predetermined direction when passing through the protective shell. This not only ensures the stability of the connection but also facilitates the assembly and disassembly of the entire bone clamp structure.

[0020] Furthermore, the length of the first connecting rod or the second connecting rod is 2-5 cm, and the angle between the first connecting rod and the clamping rod is 130°-170°.

[0021] In some embodiments, controlling the length of the connecting rod is an important factor in accurately achieving the opening and closing action of the bone clamp. A connecting rod that is too short may cause the clamp arm to rotate too much, which is not conducive to gently and firmly clamping the bone material or bone tissue; a connecting rod that is too long will reduce the efficiency of force transmission and cause unstable shaking during the movement. At the same time, this length can adapt to bone materials of different sizes and shapes. For small and fragile or large and hard bone samples, the appropriate clamping force can be provided by adjusting the specific value of the connecting rod within this length range. In this embodiment, the preferred length of the connecting rod is 2-5 cm. Within this length range, it has the best force transmission and motion conversion effect. On the one hand, when dealing with small and fragile bone specimens, a shorter connecting rod length (e.g., approximately 2 cm) allows the bone clamp to achieve gentle and moderate rotation of the clamp arms under the action of relatively small external forces, thus avoiding damage to the bone specimen caused by excessive clamp arm rotation, while at the same time ensuring sufficient clamping force to prevent the bone specimen from slipping. On the other hand, for large and hard bone specimens, a longer connecting rod length (e.g., approximately 5 cm) can effectively transmit greater external forces to the clamp arms, achieving a larger clamp arm rotation range, thereby generating sufficient clamping force to firmly fix the bone specimen. In this process, since the connecting rod length is within the appropriate range, the force transmission process is relatively stable, and there will be no shaking caused by excessive length or abnormal clamp arm rotation caused by excessive shortness. This ensures the accuracy and stability of the bone clamp opening and closing action, thereby achieving ideal results in clamping operations of different types of bone specimens.

[0022] The angle between the connecting rod and the clamping rod, ranging from 130° to 170°, optimizes the direction of force transmission from the clamping rod to the clamping arm. If the angle is too small, force transmission can cause the clamping arm to stall or unevenly apply force to the bone material. A larger angle limits the clamping arm's range of rotation, affecting proper use of the bone clamp. Furthermore, this angle helps maintain stability during the clamp's opening and closing, complementing the clamp's overall structure.

[0023] The connecting rod is preferably 2-5 cm long and angled at 130°-170°, matching the clamping rod, clamping arm, and pivoting shaft in the bone clamp. The connecting rod's length and angle, combined with its rotatable connection to the clamping rod and clamping arm, precisely control the amplitude and speed of the clamping arm's rotation when external forces act on the clamping rod. The special structure on the inner side of the clamping arm ensures a secure grip on the bone material when closed. The pivoting shaft is located in the middle of the clamping arm. As the connecting rod drives the clamping arm, its length and angle ensure smooth rotation, preventing excessive rotation that could damage the clamp or place excessive pressure on bone tissue.

[0024] In conjunction with the protective shell structure, the positioning screws on the shell determine the degree of opening and closing of the bone clamp. The length and angle of the connecting rod ensure that the bone clamp reaches the desired opening and closing state when the clamping rod moves to a specific position. The protective shell protects the internal structure of the bone clamp, and the connecting rod ensures the normal operation of the bone clamp within the protective shell's limits. Together, these two improve the reliability and accuracy of the bone fixation unit.

[0025] Furthermore, the protective shell is sleeved on the outside of the bone clamp, and a connecting hole is provided in the center of the protective shell for the clamping rod to pass through and connect with the connecting rod and the clamp arm, which is used to realize the connection between the bone clamp and the protective shell, and at the same time provide stable support and guidance for the movement of the bone clamp.

[0026] Furthermore, a concave guide groove is provided on the upper portion of the protective shell, and the clamping rod passes through the connecting hole through the concave guide groove and is connected to the connecting rod and the clamping arm, which is used to provide guidance and positioning for the clamping rod.

[0027] Furthermore, the combined connecting frame includes two side sleeves, a middle guide sleeve and a connecting beam. The two side sleeves are sleeved on the outside of the clamping rod for connecting and positioning the bone fixation unit. The middle guide sleeve passes through the connecting beam with one end exposed to maintain a stable guide path.

[0028] Furthermore, the length of the sleeve is smaller than the length of the clamping rod, so that the clamping rod is partially exposed.

[0029] Furthermore, the intermediate guide sleeve is a hollow cylindrical structure, which provides guidance for the operating rod and reduces shaking of the operating rod.

[0030] Furthermore, the connection between the connecting beam and the two side sleeves and the middle guide sleeve and the opposite side are open, so that the clamping rod and the middle guide sleeve can pass through smoothly, ensuring that the relative movement between the components is not hindered.

[0031] Furthermore, the molding depth control assembly includes an operating rod, a control component at the top of the operating rod and a positioning washer. The operating rod is provided with a scale mark and a positioning washer. The scale mark is used to measure the displacement of the operating rod. The positioning washer is detachably fixed on the operating rod and can move vertically to assist in controlling the punching depth.

[0032] Furthermore, the control component at the top end of the operating rod is a manually operated gripping structure or an automated control structure or an interface structure adapted for machine manipulation, which is used to control the movement of the operating rod.

[0033] Furthermore, the positioning washer works in conjunction with the scale mark, and the operating rod is pressed down by the control component at the top of the operating rod. When the positioning washer reaches the target position and is fixed, the operating rod is pressed down to the position to determine the punching depth, so as to accurately control the molding and punching operation.

[0034] In some embodiments, the top control component of the operating rod (which can be a manually operated gripping structure, an automated control structure, or an interface structure adapted for machine control) is the control hub for the movement of the operating rod. When performing the modeling and punching operation, the experimenter applies force through the top control component of the operating rod to move the operating rod downward along the guide sleeve according to the target punching depth. The operating rod is provided with a positioning washer and a scale mark. The positioning washer is detachably fixed to the operating rod and can move vertically on the operating rod. During the downward pressing of the operating rod, the experimenter adjusts the position of the positioning washer by observing the scale mark. When the positioning washer reaches the target position, it can be fixed. After that, the operating rod continues to be pressed down. When the operating rod is pressed down to the position where the positioning washer is located, the pressing depth of the operating rod is determined, thereby accurately controlling the punching depth. The positioning washer and the scale mark work together to effectively improve the accuracy of the modeling and punching operation, ensuring that the depth of the hole punched in the bone material or bone tissue meets the experimental requirements.

[0035] In some embodiments, the operating rod is a hollow cylindrical structure. Once a hole is drilled in the bone material, specific organoids (such as tumor cell clusters or tumor cell microspheres) can be precisely implanted at the perforated site. These organoids represent the aggregated form of tumor cells. By implanting them into specific locations in the bone material, they can more realistically simulate the growth environment of bone tumors, providing a critical pathological basis for constructing bone tumor models and ensuring the accuracy and reliability of the model.

[0036] Furthermore, the bone tumor model construction device also includes a locking mechanism, which includes a locking bolt and an internal threaded screw hole. The locking bolt is detachably fixedly connected to the internal threaded screw hole. The internal threaded screw hole is arranged on the connecting beam and / or the clamping rod to provide a fixed connection point, thereby fixing the position of the clamping rod.

[0037] Furthermore, the locking bolt is arranged on one side of the connecting crossbeam, and is used to firmly lock the clamping rod when the bone clamp is closed to clamp the bone.

[0038] In some embodiments, a specific locking mechanism, consisting of a locking bolt and an internal threaded hole, is employed to securely lock the clamping rod. Specifically, the internal threaded hole is located on the connecting beam and / or the clamping rod, and the locking bolt is positioned on one side of the connecting beam. Once the bone clamp is closed and securely clamps the bone, the operator can easily thread the locking bolt into the internal threaded hole. The locking bolt and internal threaded hole are removably connected, facilitating installation and removal when necessary while also providing sufficient clamping force during operation to securely hold the clamping rod in place.

[0039] During the construction of bone tumor models, this locking mechanism can effectively prevent the clamping rod from loosening due to external forces or improper operation. On the one hand, after the locking bolt is screwed into the internal threaded hole, its head exerts downward pressure on the clamping rod, increasing the friction between the clamping rod and the protective shell, thereby preventing the clamping rod from accidentally moving during operation; on the other hand, the external thread of the locking bolt and the internal threaded hole fit tightly together to form a reliable mechanical connection, further enhancing the locking effect. This ensures that the bone clamp always stably clamps the bone material or bone tissue, providing a reliable fixation foundation for subsequent modeling operations. This achieves the goal of improving the accuracy and stability of bone tumor model construction and ensures the smooth progress of the entire construction process. At the same time, this structural design makes operation more convenient and efficient. The operator can perform the locking operation quickly and accurately, reducing the operational risks and errors caused by loosening of the clamping rod.

[0040] The beneficial effects of the utility model are:

[0041] 1. The utility model provides a bone tumor model construction device, which plays a key role in firmly fixing bone materials or bone tissues through the structural design of the bone fixation unit. The bone clamp structure in the bone fixation unit is exquisitely designed, and is composed of a clamping rod, a clamping arm, a connecting rod and other components. The clamping rod serves as a driving component, which can accurately convert external force into the movement of the clamping arm. The clamping arm is symmetrical and specially designed on the inner side to ensure uniform pressure and prevent sliding when clamping bone materials. This structure realizes the stable and effective clamping function of the bone clamp. At the same time, the protective shell works in conjunction with the bone clamp, and the positioning screws on the protective shell accurately control the opening and closing degree of the bone clamp to ensure the accuracy and repeatability of the operation. The protective shell protects the internal structure of the bone clamp, and its connection structure design not only ensures the stability of the connection with the bone clamp, but also facilitates assembly and disassembly, providing a solid foundation for subsequent modeling operations as a whole.

[0042] 2. The bone tumor model construction device provided by the present invention effectively improves the accuracy, stability and versatility of bone model construction through the coordinated cooperation of the bone fixation unit, the combined connection frame and the modeling depth control component, and has a good effect in meeting the needs of various bone research experiments. Among them, the bone fixation unit is responsible for stabilizing the bone material, and the combined connection frame plays an important role in connecting and positioning the various components. The sleeve tube, connecting beam and other components in its "mountain"-shaped combined frame structure cooperate with each other to accurately connect the bone fixation unit and ensure the accuracy of the operating rod movement, reduce shaking, and improve the accuracy of the modeling operation. The top control component of the operating rod, the scale mark and the positioning washer in the modeling depth control component work together to accurately control the drilling depth and meet the experimental requirements for drilling accuracy. The operating rod is a hollow cylindrical structure. After the drilling is completed on the bone material, specific organoids (such as tumor cell clusters or tumor cell microspheres, etc.) can be accurately implanted into the drilling site. This organoid represents the aggregated form of tumor cells. By implanting it into specific locations on bone material, it can more realistically simulate the growth environment of bone tumors, providing a critical pathological basis for building bone tumor models and ensuring the accuracy and reliability of the modeling. The three elements work together to enable the device to adapt to different types of bone materials or bone tissues. In various bone research experimental scenarios, whether it is fixation, drilling, or drug injection, it can ensure high precision and stability, thereby promoting the continuous development of bone-related research and has excellent application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 This is the front view of the bone tumor model construction device of the present invention (with the clamping arms closed).

[0044] Figure 2 This is a three-dimensional diagram of the bone tumor model construction device of the present invention (with the clamping arms closed).

[0045] Figure 3 This is a three-dimensional structural diagram of the bone tumor model construction device of the present invention (with the clamping arms open).

[0046] Figure 4 This is an exploded view of the device for constructing a bone tumor model in this utility model.

[0047] Figure 5 This is a front view of the clamping structure (with the clamping arms open) in the bone tumor model construction device of the present invention.

[0048] Figure 6 This is a front view of the clamping structure (with the clamping arms closed) in the bone tumor model construction device of the present invention.

[0049] Figure 7 This is the main view of the modeling depth control component in the bone tumor model construction device of the present invention.

[0050] Figure 8 A three-dimensional structural diagram of the locking mechanism (with the clamp arms open) after optimization of the bone tumor model construction device of the present invention.

[0051] Figure 9 An exploded view of the locking mechanism was added after the device was optimized for the bone tumor model construction of the utility model. DETAILED DESCRIPTION

[0052] The present invention will be described in further detail below in conjunction with the embodiments. It should be noted that the embodiments described below are intended to facilitate understanding of the present invention and do not have any limiting effect on the present invention.

[0053] Unless otherwise specified, the experimental methods used in the following examples are conventional methods.

[0054] Unless otherwise specified, the materials and reagents used in the following examples can be obtained from commercial sources.

[0055] Example 1 A bone tumor model construction device provided by the present invention

[0056] 1. Basic structure of the bone tumor model construction device

[0057] This embodiment provides a bone model construction device such as Figures 1 to 7 shown.

[0058] from Figures 1 to 7 It can be seen that the bone model construction device mainly consists of three parts: a bone fixation unit, a combined connection frame, and a modeling depth control component.

[0059] 1. Bone fixation unit

[0060] The bone fixation unit includes a first clamping structure and a second clamping structure, and the first clamping structure and the second clamping structure have the same structure. The clamping structure includes a bone clamp, a protective shell 1 and a rotating shaft 2.

[0061] The bone clamp includes a clamping rod 3, a first clamping arm 4, a second clamping arm 5, a first connecting rod 6, and a second connecting rod 7. The clamping rod 3 is the control component of the bone clamp, responsible for transmitting the external driving force to achieve up and down movement, and has good linear motion accuracy to ensure that the opening and closing of the bone clamp can be accurately controlled during operation. The length of the clamping rod 3 is determined according to the overall size of the bone clamp and the operational requirements, and its cross-sectional shape is circular or rectangular to facilitate connection with the first connecting rod 6 and the second connecting rod 7 and ensure stability during movement. In this embodiment, the length of the clamping rod 3 is 10-20 cm, specifically 18 cm, and its cross-sectional shape is circular. The first clamping arm 4 and the second clamping arm 5 are symmetrically designed and are components that directly contact the bone material 8 or bone tissue and realize the clamping function. The maximum diameter of the bone material 8 is 3 cm. The inner surfaces of the first clamping arm 4 and the second clamping arm 5 are designed with rough texture or serrated to increase the friction between the bone tissue and prevent the bone tissue from sliding during the clamping process. At the same time, the materials of the clamping arms include anti-slip pads and metal clamps, which have good compatibility with bone tissue to avoid damage to the bone tissue and have sufficient strength to withstand the clamping force. At the same time, a first connecting rod 6 is connected between the clamping rod 3 and the first clamping arm 4, and a second connecting rod 7 is connected between the clamping rod 3 and the second clamping arm 5. The first connecting rod 6 and the second connecting rod 7 are close to one end of the clamping rod 3 and are connected to the clamping rod 3 by a hinge or pin or other rotatable connection method. The other end is also connected to the first clamping arm 4 and the second clamping arm 5 in a rotatable connection method. The connecting rod is shaped like a slender rod. Its length and angle are key to achieving the opening and closing of the bone clamp. The length is 2-5 cm, and the angle between it and the clamping rod 3 is 130°-170°. In this embodiment, the connecting rod is specifically 2 cm long and the angle between it and the clamping rod 3 is 150°. Taking the first clamping arm 4 as an example, when the clamping rod 3 moves downward, one end of the first connecting rod 6 connected to the clamping rod 3 moves downward accordingly. Because the connecting rod length is fixed and the end connected to the first clamping arm 4 can only rotate about the connection point, this causes the other end of the first connecting rod 6 connected to the first clamping arm 4 (the end away from the clamping rod 3) to move upward, thereby causing the first clamping arm 4 to rotate inward and close around the rotating axis 2 at its middle end. Because the first clamping arm 4 and the second clamping arm 5 are connected in the same and symmetrical manner, when the clamping rod 3 moves downward, the first clamping arm 4 and the second clamping arm 5 will simultaneously rotate inward and close, thereby clamping the bone material 8 or bone tissue. The design of this connecting rod mechanism can convert the linear motion of the clamping rod 3 into the rotational motion of the clamping arm, achieving precise motion transmission and force conversion, and ensuring that the bone clamp can perform a stable and effective clamping operation.

[0062] The protective shell 1 is equipped with a set screw 9 and a rotating shaft 2. The rotating shaft 2 is located in the middle of the clamp arms and removably secures the bone clamp to the protective shell 1. When the clamping rod 3 is in its initial position, i.e., the bottom end of the clamping rod 3 is flush with the set screw 9 located at the top of the protective shell 1, the bone clamp is not subject to any external force for closing. Supported by the rotating shaft 2, the two clamp arms remain naturally open. This open position facilitates the placement of bone material 8 or bone tissue between the two clamp arms, preparing for subsequent clamping operations. When an external force is applied to the bone clamp, causing the clamping rod 3 to move downward a certain distance, the bottom of the clamping rod 3 is now a certain distance below the set screw 9 located at the top of the protective shell 1. During this process, the downward movement of the clamping rod 3 causes the two clamp arms to rotate about the rotating shaft 2. Because the lower portion of the protective shell 1 is connected to the clamp arms by the rotating shaft 2, the rotating shaft 2 limits excessive rotation of the clamp arms, allowing the two clamp arms to gradually close under the rotation of the rotating shaft 2. When the predetermined closing degree is reached, the bone clamp tightly clamps the bone material 8 or bone tissue, thereby achieving a stable clamping function and providing a reliable fixing basis for subsequent modeling operations (such as drilling, injection, etc.).

[0063] The protective shell 1 is sleeved on the outside of the upper part of the bone clamp, so that the lower part of the bone clamp (the lower half of the clamp arm) is exposed. A connecting hole 11 is provided in the center of the protective shell 1, through which the clamping rod 3 passes to be detachably fixedly connected to the connecting rod and the clamp arm. A concave guide groove 10 with an opening is also provided on the upper part of the protective shell 1. The clamping rod 3 passes through the connecting hole 11 through the concave guide groove 10 and is connected to the connecting rod and the clamp arm. The size of the concave guide groove 10 is precisely adapted to the clamping rod 3 to ensure that the clamping rod 3 can pass through smoothly and fluently. This design not only ensures the stability of the connection, but also greatly facilitates the assembly and disassembly operations.

[0064] 2. Combined connection framework

[0065] The bone fixation unit (the first clamping structure and the second clamping structure) is removably connected via a combined connecting frame. The combined connecting frame comprises a "mountain"-shaped combined frame structure that acts as a protective sleeve and fits over the clamping rod 3 of the bone fixation unit. The "mountain"-shaped combined frame includes two side sleeves 12, a central guide sleeve 13, and a horizontal connecting crossbeam 14. This "mountain"-shaped combined frame not only effectively connects the bone fixation unit but also guides the movement of the operating rod 15, thereby playing a vital role in connection, positioning, and guidance during the bone modeling process.

[0066] The sleeves 12 on either side are hollow cylindrical structures, with their axial direction aligned with the vertical direction. Both ends of the sleeves 12 are open, making them easy to fit over the clamping rod 3. The inner diameter of the sleeves 12 matches the outer diameter of the clamping rod 3, ensuring a stable fit. The length of the sleeves 12 is shorter than that of the clamping rod 3, allowing the clamping rod 3 to be partially exposed above the sleeves 12. This partially exposed design ensures that the sleeves 12 effectively position and connect the clamping rod 3 while retaining a certain degree of freedom for the clamping rod 3, facilitating coordinated operation with other structures.

[0067] The middle guide sleeve 13 is also a hollow cylindrical structure. Its main function is to provide precise guidance for the operating rod 15 (such as the depth control operating rod 15) to ensure that the operating rod 15 can move accurately in the vertical direction. The inner diameter of the guide sleeve 13 is precisely adapted to the outer diameter of the operating rod 15 to reduce the shaking of the operating rod 15 during movement and improve the accuracy of operation. The guide sleeve 13 passes through the connecting crossbeam 14, and one end is exposed. This through-hole design allows the guide sleeve 13 to maintain a stable vertical position under the restriction of the connecting crossbeam 14, providing a stable guide path for the movement of the operating rod 15.

[0068] The connecting crossbeam 14 is a horizontal structural component that, together with the sleeves 12 on either side and the guide sleeve 13 in the middle, forms a "mountain"-shaped composite frame. The connecting crossbeam 14 is open at the connection points with the sleeves 12 on either side and the guide sleeve 13 in the middle, as well as on the opposite sides of the connection points. The openings at the connection points with the sleeves 12 and the guide sleeve 13 and on the opposite sides allow the clamping rod 3 to pass through smoothly, while also allowing the guide sleeve 13 in the middle to pass through. This opening design ensures the convenience of the entire "mountain"-shaped composite frame structure during assembly and ensures that the relative movement between the various components is unimpeded during operation, maintaining the integrity and functionality of the entire structure.

[0069] 3. Molding depth control component

[0070] The molding depth control assembly includes an operating rod 15 , a control component 16 at the top of the operating rod, and a positioning washer 17 .

[0071] The operating rod 15 is provided with a positioning washer 17 and a scale mark. The positioning washer 17 is detachably fixed to the operating rod 15 and can be moved vertically on the operating rod 15. The setting of the scale mark can accurately measure the displacement of the operating rod 15. The experimenter can control the position of the positioning washer 17 by observing the scale mark according to the target drilling depth. When the positioning washer 17 reaches the target position, it can be fixed to determine the depth of the drilling, which greatly improves the accuracy of the modeling drilling operation. The bottom end of the operating rod 15 is designed to be serrated, which is convenient for drilling. During the modeling drilling operation, the serrated design is conducive to maintaining the smoothness and stability of the drilling, thereby ensuring the accuracy of the modeling depth. The operating rod 15 is a hollow cylindrical structure. After the drilling is completed on the bone material, specific organoids (such as tumor cell clusters or tumor cell microspheres, etc.) can be accurately implanted into the drilling site. This organoid represents the aggregated morphology of tumor cells. By implanting it into a specific location of the bone material, it can more realistically simulate the growth environment of bone tumors, provide a key pathological basis for constructing a bone tumor model, and thus ensure the accuracy and reliability of the modeling.

[0072] The top of the joystick 15 is equipped with a detachable top control member 16, which can be a manual grip, an automated control structure, or an interface structure suitable for machine control. The manual grip structure facilitates direct operation by the experimenter, while the automated control structure or machine control interface structure is suitable for experimental scenarios controlled by automated equipment, allowing for more precise and efficient control of the movement of the joystick 15.

[0073] 2. The role of different structures in the bone tumor model construction device

[0074] The bone tumor model construction device provided by the present invention has the following functions in different structures:

[0075] (1) Clamping rod 3: As the control component of the bone clamp, it is the driving element of the bone clamp action. It is responsible for transmitting the externally applied force to the entire bone clamp structure, driving the connecting rod movement through its own up and down movement, and then controlling the opening and closing movement of the clamp arm. Its good linear motion accuracy ensures the accuracy of the opening and closing movement of the bone clamp, and accurately controls the moving distance of the clamp arm during operation, thereby achieving stable clamping or release of the bone material 8 or bone tissue. Its length and cross-sectional shape are designed to effectively connect with other components (such as the connecting rod) and remain stable during movement, providing stable mechanical support for the entire bone clamp structure.

[0076] (2) Clamping arm: includes a first clamping arm 4 and a second clamping arm 5. The first clamping arm 4 and the second clamping arm 5 are key components that directly contact the bone material 8 or bone tissue and realize the clamping function. Its symmetrical design enables uniform pressure to be applied to the bone material 8 or bone tissue during the clamping process. The rough texture or serrated structure designed on the inner surface effectively increases the friction between the bone tissue and prevents the bone tissue from sliding during the clamping process. The choice of its material (which has good compatibility with bone tissue and has sufficient strength) not only avoids damage to the bone tissue, but also can withstand the clamping force, ensuring that the bone material 8 or bone tissue can be firmly fixed during the modeling operation, providing a reliable basis for subsequent operations such as drilling and injection.

[0077] (3) Connecting rod: It includes a first connecting rod 6 and a second connecting rod 7. The first connecting rod 6 and the second connecting rod 7 play a key role in force transmission and motion conversion in the bone clamp structure. One end thereof is connected to the clamping rod 3 (clamping rod 3) by a rotatable connection, and the other end is connected to the clamping arm by a rotatable connection. This connection constitutes a connecting rod mechanism. The slender rod-shaped structure of the connecting rod and the specific length (2 cm in this embodiment) and angle (the angle between the clamping rod 3 and the clamping arm is 150°) design can convert the linear motion of the clamping rod 3 into the rotational motion of the clamping arm. When the clamping rod 3 moves up and down, the connecting rod drives the clamping arm to rotate around the rotating shaft 2 through its own rotation, thereby achieving precise motion transmission and force conversion, ensuring that the bone clamp can stably and effectively perform clamping or loosening operations according to operational requirements.

[0078] (4) Protective shell 1: On the one hand, the protective shell 1 protects the bone clamp and prevents external factors from interfering with or damaging the internal structure of the bone clamp (such as the rotating shaft 2, connecting rod, etc.). On the other hand, the protective shell 1 realizes a detachable fixed connection with the bone clamp through its structural design, providing a limit and guide function for the movement of the bone clamp. The positioning screw 9 on the protective shell 1 is used to determine the initial state and range of movement of the bone clamp. The central connection hole 11 and the concave guide groove 10 with an opening on the upper part cooperate with the clamping rod 3 to ensure that the clamping rod 3 can pass smoothly and smoothly and achieve a stable connection with other components, while ensuring the stability of the connection and facilitating assembly and disassembly operations.

[0079] (5) Positioning screw 9: The positioning screw 9 plays a key role in positioning and limiting the connection between the bone clamp and the protective shell 1. When the clamping rod 3 is in the initial position, the bottom end of the clamping rod 3 is flush with the positioning screw 9 at the upper position of the protective shell 1. This position determines the initial opening state of the bone clamp. During the closing process of the bone clamp, the positioning screw 9 serves as a reference point. When the clamping rod 3 moves down to a certain extent (the bottom is a certain distance lower than the positioning screw 9. In this embodiment, the certain distance is 0-2 cm, specifically 1 cm), the bone clamp reaches a predetermined closing degree, thereby achieving stable clamping of the bone material 8 or bone tissue. The positioning screw 9 accurately controls the opening and closing degree of the bone clamp, ensuring the accuracy and repeatability of the clamping operation.

[0080] (6) Rotating shaft 2: Rotating shaft 2 is located in the middle of the clamp arm and is the core hub for the bone clamp to open and close. It enables the clamp arm to rotate around it, thereby realizing the opening and closing functions of the bone clamp. During the opening and closing process of the bone clamp, the rotating shaft 2 supports the rotational movement of the clamp arm, ensuring the stability and accuracy of the clamp arm during the movement. At the same time, when the lower part of the protective shell 1 is connected to the clamp arm through the rotating shaft 2, the rotating shaft 2 also plays a role in limiting the excessive rotation of the clamp arm, ensuring that the bone clamp can stably clamp the bone material 8 or bone tissue when closing, avoiding damage to the bone clamp or excessive pressure on the bone tissue due to excessive closing.

[0081] (7) Concave guide groove 10: The concave guide groove 10 is located on the upper part of the protective shell 1. Its main function is to provide guidance and positioning functions for the clamping rod 3. The size of the concave guide groove 10 is precisely adapted to the clamping rod 3. When the clamping rod 3 passes through the connecting hole 11 of the protective shell 1, the concave guide groove 10 ensures that the clamping rod 3 can pass smoothly and fluently in the predetermined direction, preventing the clamping rod 3 from deflecting or shaking during movement. This precise guiding function helps maintain the stability of the bone clamp structure and also facilitates the assembly and disassembly process of the entire bone clamp structure.

[0082] (8) “Mountain” shaped composite frame: It includes sleeves 12 on both sides, a guide sleeve 13 in the middle and a horizontal connecting beam 14.

[0083] The sleeves 12 on both sides are part of the "mountain"-shaped combined frame, and mainly play the role of connecting and positioning the bone fixation units (the first clamping structure and the second clamping structure). Its hollow cylindrical structure design with openings at both ends makes it easy to be sleeved on the outside of the clamping rod 3. Through the sleeve connection with the clamping rod 3, the two bone fixation units are relatively fixed in the horizontal direction. Its inner diameter matches the outer diameter of the clamping rod 3 to ensure the stability of the connection. The length of the sleeve 12 is less than the length of the clamping rod 3, so that the clamping rod 3 is partially exposed on the upper part of the sleeve 12. This design not only realizes the effective positioning and connection of the clamping rod 3, but also retains a certain degree of freedom of the clamping rod 3, so that the clamping rod 3 is not subject to excessive restrictions during other operations (such as coordinated action with the bone clamp), thereby ensuring the collaborative working ability of the entire device.

[0084] The middle guide sleeve 13 provides precise guidance for the operating rod 15. Its inner diameter is precisely matched to the outer diameter of the operating rod 15, so that the operating rod 15 can move along the axis of the guide sleeve 13 when performing vertical movement up and down, effectively reducing the shaking of the operating rod 15 during movement, thereby improving the accuracy of the operation. During the bone modeling process, especially when performing drilling operations, the precise guidance can ensure that the operating rod 15 accurately reaches the predetermined position, thereby improving the accuracy of the modeling. Its design of passing through the connecting crossbeam 14 with one end exposed allows the guide sleeve 13 to maintain a stable vertical position under the constraint of the connecting crossbeam 14, further enhancing the guiding effect on the operating rod 15.

[0085] The connecting crossbeam 14, as a horizontal structural component in the "mountain"-shaped composite frame, serves to connect the two side sleeves 12 and the middle guide sleeve 13, combining the three into an integrated "mountain"-shaped structure. Its design, with openings at the connection points with the two side sleeves 12 and the middle guide sleeve 13, as well as on the opposite sides of the connection points, ensures that the clamping rod 3 can smoothly pass through the entire "mountain"-shaped composite frame structure, while also allowing the middle guide sleeve 13 to pass through. This open design greatly facilitates the assembly process of the device while ensuring structural integrity. It also ensures that the relative movement between the various components is unimpeded during operation, maintaining the connection, positioning, and guiding functions of the entire "mountain"-shaped composite frame structure.

[0086] (9) Operating rod 15: The operating rod 15 is the core component of the modeling depth control assembly and is directly involved in the punching operation during the modeling process. Under the action of the control component 16 at the top of the operating rod, it moves vertically along the guide sleeve 13, transmits the externally applied force to the working end, and realizes the punching action of the bone material 8 or bone tissue. The scale mark and positioning washer 17 set on the operating rod 15 enable the operating rod 15 to accurately control the punching depth, and is a key execution component for achieving accurate modeling punching operations. The operating rod 15 is a hollow cylindrical structure. After the punching is completed on the bone material, specific organoids (such as tumor cell clusters or tumor cell microspheres, etc.) can be accurately implanted into the punching site. This organoid represents the aggregation morphology of tumor cells. By implanting it into a specific position of the bone material, the growth environment of the bone tumor can be more realistically simulated, providing a key pathological basis for constructing a bone tumor model, thereby ensuring the accuracy and reliability of the modeling.

[0087] (10) Operating rod top control component 16: The operating rod top control component 16 provides a means of controlling the movement of the operating rod 15. Its different forms (manually operated gripping structure, automated control structure or interface structure adapted to machine control) are adapted to different experimental scenarios and operational requirements. The manual gripping structure facilitates direct operation by the experimenter based on his or her own experience and actual observation, and has the advantage of operational flexibility; the automated control structure or machine control interface structure is suitable for experimental scenarios controlled by automated equipment, and can accurately and efficiently control the movement of the operating rod 15 through preset programs or external control equipment, thereby improving the accuracy and repeatability of the operation and meeting the requirements of large-scale, high-precision modeling experiments.

[0088] (11) Positioning washer 17: The positioning washer 17 plays an auxiliary role in controlling the drilling depth in the modeling depth control assembly. It is detachably fixed to the operating rod 15 and can be moved vertically on the operating rod 15. During the modeling operation, the experimenter adjusts the position of the positioning washer 17 according to the target drilling depth by observing the scale mark on the operating rod 15. When the operating rod 15 is pressed down to perform the drilling operation, the positioning washer 17 can be fixed after reaching the target position. At this time, the pressing depth of the operating rod 15 is determined, thereby accurately controlling the drilling depth. The positioning washer 17 works in conjunction with the scale mark to effectively improve the accuracy of the modeling drilling operation and ensure that the depth of the hole drilled in the bone material 8 or bone tissue meets the experimental requirements.

[0089] 3. Working Principle of the Bone Tumor Model Construction Device

[0090] This utility model designs a new bone tumor model construction device, the working principle of which is as follows:

[0091] The core operating principle of the bone clamp lies in the bone fixation unit. Initially, the clamp's clamping rod 3 is in a specific position, flush with the positioning screw 9 on the upper portion of the protective shell 1. Supported by the pivot 2, the clamp arms remain naturally open, making it easy to place bone material 8 or bone tissue between the arms. When clamping is required, an external force is applied to move the clamping rod 3 downward. Because the clamping rod 3 and the clamp arms are connected by a connecting rod, with each end of the connecting rod rotatably connected to the clamping rod 3 and the clamp arms, respectively, this connection constitutes a unique linkage mechanism. For example, when the clamping rod 3 moves downward, one end of the connecting rod connected to the clamping rod 3 also descends. Because the connecting rod is fixed in length and the other end can only rotate about its connection point, this end moves upward, causing the clamp arms to rotate inward and close around their central pivot 2. Because the two clamp arms are symmetrical and connected identically, they rotate inward and close simultaneously, clamping the bone material 8 or bone tissue. During this process, the protective shell 1 performs multiple functions. It not only protects the internal structures of the bone clamp, such as the rotating shaft 2 and connecting rod, from interference or damage from external factors, but also the positioning screw 9 on the protective shell 1 precisely determines the initial opening state of the bone clamp and serves as an important reference point when the bone clamp is closed. When the clamping rod 3 moves downward to a certain degree (the bottom is a certain distance below the positioning screw 9), the bone clamp reaches the predetermined closing degree, thereby achieving precise control over the opening and closing degree of the bone clamp. Furthermore, the protective shell 1, through its central connecting hole 11 and the concave guide groove 10 on the upper portion that precisely fits the clamping rod 3, ensures that the clamping rod 3 can move smoothly and fluidly in the predetermined direction when passing through the protective shell 1. This not only ensures the stability of the connection but also facilitates the assembly and disassembly of the entire bone clamp structure.

[0092] The combined connecting frame plays an important role in connection, positioning and guidance in the device. Among them, the sleeve tubes 12 on both sides of the "mountain"-shaped combined frame structure are hollow cylindrical structures with upper and lower openings. Their inner diameter matches the outer diameter of the clamping rod 3 of the bone fixation unit. By being sleeved on the outside of the clamping rod 3, the two bone fixation units (the first clamping structure and the second clamping structure) are relatively fixed in the horizontal direction. The length of the sleeve tube 12 is less than the length of the clamping rod 3. This design allows the clamping rod 3 to be partially exposed on the upper part of the sleeve tube 12, which not only ensures the effective positioning and connection of the clamping rod 3, but also retains a certain degree of freedom of the clamping rod 3 so that it can cooperate with the bone clamp. The connecting crossbeam 14 serves as a horizontal structural component, connecting the sleeve tubes 12 on both sides and the middle guide sleeve 13 to form an overall "mountain"-shaped structure. The connecting crossbeam 14 is provided with openings at the connection with the sleeve 12 and the guide sleeve 13, as well as on the opposite side of the connection. These openings ensure that the clamping rod 3 can smoothly pass through the entire "mountain"-shaped combined frame structure, while also allowing the middle guide sleeve 13 to pass through. This design not only facilitates the assembly process of the device, but also ensures that the relative movement between the various components is not hindered during operation, thereby maintaining the integrity and functionality of the entire structure. The middle guide sleeve 13 mainly provides a precise guiding function for the operating rod 15 (such as the depth control operating rod 15). Its inner diameter is precisely adapted to the outer diameter of the operating rod 15, so that the operating rod 15 can only move along the axis of the guide sleeve 13 when moving in the up and down vertical directions, effectively reducing the shaking of the operating rod 15 during movement. The design of the guide sleeve 13 passing through the connecting beam 14 with one end exposed allows the guide sleeve 13 to maintain a stable vertical position under the constraint of the connecting beam 14, further enhancing the guiding effect on the operating rod 15, ensuring that the operating rod 15 can accurately reach the predetermined position during the bone modeling process (especially during the drilling operation), thereby improving the accuracy of the modeling.

[0093] For the molding depth control component, the top control component 16 of the operating rod (which can be a manually operated gripping structure, an automated control structure, or an interface structure adapted for machine control) is the control hub for the movement of the operating rod 15. When performing the molding punching operation, the experimenter applies force through the top control component 16 of the operating rod according to the target punching depth to move the operating rod 15 downward along the guide sleeve 13. The operating rod 15 is provided with a positioning washer 17 and a scale mark. The positioning washer 17 is detachably fixed on the operating rod 15 and can be moved vertically on the operating rod 15. During the downward pressing process of the operating rod 15, the experimenter adjusts the position of the positioning washer 17 by observing the scale mark. When the positioning washer 17 reaches the target position, it can be fixed. After that, the operating rod 15 continues to be pressed down. When the operating rod 15 is pressed down to the position of the positioning washer 17, the pressing depth of the operating rod 15 is determined, thereby accurately controlling the punching depth. The positioning washer 17 and the graduated markings work together to effectively improve the accuracy of the modeling and drilling operation, ensuring that the depth of the hole in the bone material 8 or bone tissue meets the experimental requirements. Furthermore, once the hole is drilled in the bone material, the operating rod 15 can be used to precisely implant a specific organoid into the hole. This organoid represents the aggregated form of tumor cells. By implanting it into a specific location in the bone material, it can more realistically simulate the growth environment of bone tumors, providing a critical pathological basis for constructing bone tumor models and ensuring the accuracy and reliability of the modeling.

[0094] In summary, the bone tumor model construction device of the present invention achieves stable clamping of bone materials or bone tissue through the bone fixation unit, the combined connection frame ensures the connection, positioning and guidance of the operating rod of each component, and the modeling depth control component accurately controls the drilling depth. The various structures work together to achieve efficient and accurate bone model construction operations.

[0095] Example 2 Optimization of a bone tumor model construction device provided by the utility model

[0096] In this embodiment, in order to further improve the stability and reliability of the device and ensure that the bone clamp will not loosen due to unexpected circumstances after clamping the bone, further optimization is performed based on the original structure of Example 1: a locking mechanism is added.

[0097] The design of the locking mechanism is as follows: Figure 8-9 shown.

[0098] 1. Design of the locking mechanism

[0099] Two externally threaded locking bolts 18 are provided on one side of the connecting crossbeam 14. The length and diameter of the locking bolts 18 are precisely designed to ensure they securely secure the clamping rod 3 without significantly compromising the structural strength of the connecting crossbeam 14. The heads of the locking bolts 18 are provided with convenient tool interfaces, such as hexagonal or cross-shaped grooves, to facilitate tightening and loosening using appropriate tools.

[0100] On the same side where the clamping rod 3 contacts the connecting beam 14, a plurality of internal threaded holes 19 are provided on the clamping rod 3, and the specific number may be between 1 and 6. The function of the internal threaded holes is to provide a plurality of fixing point options for the locking bolt 18 to adapt to different working scenarios and needs. When the bone tumor model construction device is used to clamp bones of different sizes, by adjusting the downward movement distance of the clamping rod 3, the internal threaded holes in different positions can be selected to correspond to the internal threaded holes on the connecting beam 14. In this way, regardless of whether the size of the bone is large or small, it can ensure that the clamping rod 3 is firmly locked in the appropriate position, thereby providing a stable clamping force for the bone clamp.

[0101] Connecting crossbeam 14 also features an internally threaded hole corresponding to internally threaded hole 19 on clamping rod 3. The depth and thread size of internally threaded hole 19 precisely match those of locking bolt 18, ensuring that when tightened, sufficient clamping force is generated to secure the position of clamping rod 3. This precise fit not only ensures a secure connection between locking bolt 18 and internally threaded hole 19 but also prevents loosening or slipping during use. Furthermore, the appropriate thread depth and size ensure that locking bolt 18 does not damage the structure of clamping rod 3 or connecting crossbeam 14 when screwed into internally threaded hole 19, thus ensuring the safety and stability of the device.

[0102] 2. Working principle of locking mechanism

[0103] After the clamping rod moves downward a certain distance, allowing the bone clamp to close and clamp the bone, the operator selects the appropriate internal threaded hole based on the bone size, aligns the locking bolt with the internal threaded hole on the clamping rod, and uses the appropriate tool to screw the locking bolt into the internal threaded hole. As the locking bolt is screwed in, its head gradually approaches the connecting beam, exerting downward pressure on the clamping rod. Due to the friction between the clamping rod and the protective shell, this pressure increases the friction between the clamping rod and the protective shell, thereby preventing the clamping rod from accidentally moving during operation.

[0104] At the same time, the external thread of the locking bolt fits tightly with the internal thread hole on the clamping rod, forming a reliable mechanical connection, further enhancing the locking effect. When the clamping rod needs to be loosened, the operator only needs to use a tool to reverse the locking bolt to remove it from the internal thread hole.

[0105] 3. Advantages of Locking Mechanism

[0106] 1. Simple structure and high reliability

[0107] The locking mechanism consists of a simple locking bolt and an internally threaded hole. This simple structure is not only easy to manufacture and install, but also highly reliable. During use, as long as the machining and fitting accuracy of the locking bolt and the internally threaded hole are ensured, the clamping rod can be effectively prevented from loosening.

[0108] 2. Easy to operate and high efficiency

[0109] The locking mechanism of this embodiment is very easy to operate. Simply use the appropriate tool to screw the locking bolt into or out of the internally threaded hole. This operation requires no complex steps or specialized skills, making it easily accessible even to non-professionals. Furthermore, because the locking bolt can be tightened and loosened very quickly, work efficiency can be greatly improved.

[0110] 3. Compatible with the original structure

[0111] The locking mechanism was designed with full consideration for compatibility with the existing structure of the bone tumor model construction device. The locking bolt is installed on one side of the connecting beam, without affecting the structure and function of other components such as the sleeve. Furthermore, the internal threaded hole in the clamping rod can be machined without affecting the clamp's clamping function, ensuring the integrity and functionality of the entire device.

[0112] In summary, by adding a locking mechanism to the bone tumor model construction device, the stability and reliability of the bone tumor model construction device of the present invention are further improved, providing a more solid guarantee for the construction of the bone tumor model.

[0113] In the description of the present invention, it should be understood that the terms "center", "lateral", "up", "down", "left", "right", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0114] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Anyone familiar with this technology may make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention should be based on the definition of the claims.

Claims

1. A bone tumor model construction device, characterized in that: It includes a bone fixation unit, a combined connection frame, and a modeling depth control component, wherein the bone fixation unit, the combined connection frame, and the modeling depth control component are combined into a detachable integrated structure; The bone fixation unit is used to achieve a stable clamping of bone material or bone tissue; The combined connection frame is used to realize the connection and positioning of the bone fixation unit and to guide the modeling depth control component; The molding depth control component is used to control the punching depth during the molding process.

2. The bone tumor model construction device according to claim 1, characterized in that: The bone fixation unit includes a clamping structure, which includes a bone clamp, a protective shell and a rotating shaft. The bone clamp includes a clamping rod, a first clamping arm, a second clamping arm, a first connecting rod and a second connecting rod. The first connecting rod connects the clamping rod and the first clamping arm, and the second connecting rod connects the clamping rod and the second clamping arm, and is used to convert the linear motion of the clamping rod into the rotational motion of the clamping arm to realize the opening and closing of the bone clamp, thereby firmly clamping the bone material or bone tissue.

3. The bone tumor model construction device according to claim 2, characterized in that: The protective shell is provided with a positioning screw and a rotating shaft. The rotating shaft is located in the middle of the first clamp arm or the second clamp arm, so that the bone clamp is detachably connected to the protective shell. The positioning screw is used to determine the initial state of the bone clamp and serves as a reference point when the bone clamp is closed. The degree of opening and closing of the bone clamp is controlled by the position relationship with the clamping rod.

4. The bone tumor model construction device according to claim 3, characterized in that: When the clamping rod is in the initial position, the first clamping arm and the second clamping arm remain open, making it easy to place bone material or bone tissue between the first clamping arm and the second clamping arm; when external force is applied to the clamping rod to move it downward, the downward movement of the clamping rod drives the first clamping arm and the second clamping arm to rotate around the rotating shaft, causing them to gradually close until the bone clamp tightly clamps the bone material or bone tissue, providing a reliable fixation foundation for subsequent modeling operations.

5. The bone tumor model construction device according to claim 4, characterized in that: When the clamping rod is at the initial position, the bottom end of the clamping rod is flush with the positioning screw on the protective shell; when an external force is applied to the clamping rod to move it downward, the bottom end of the clamping rod is lower than the positioning screw.

6. The bone tumor model construction device according to claim 5, characterized in that: The length of the first connecting rod or the second connecting rod is 2-5 cm, and the angle between the first connecting rod and the clamping rod is 130°-170°.

7. The bone tumor model construction device according to claim 6, characterized in that: The protective shell is arranged on the outside of the bone clamp. A connecting hole is provided in the center of the protective shell for the clamping rod to pass through and connect to the connecting rod and the clamping arm, which is used to realize the connection between the bone clamp and the protective shell, and at the same time provide stable support and guidance for the movement of the bone clamp.

8. The bone tumor model construction device according to claim 7, characterized in that: A concave guide groove is provided on the upper part of the protective shell. The clamping rod passes through the connecting hole through the concave guide groove and is connected to the connecting rod and the clamping arm, which is used to provide guidance and positioning for the clamping rod.

9. The bone tumor model construction device according to claim 8, characterized in that: The combined connecting frame includes two side sleeves, a middle guide sleeve and a connecting beam. The two side sleeves are sleeved on the outside of the clamping rod for connecting and positioning the bone fixation unit. The middle guide sleeve passes through the connecting beam with one end exposed to maintain a stable guide path.

10. The bone tumor model construction device according to claim 9, characterized in that: The molding depth control assembly includes an operating rod, a control component at the top of the operating rod and a positioning washer. The operating rod is provided with a scale mark and a positioning washer. The scale mark is used to measure the displacement of the operating rod. The positioning washer is detachably fixed on the operating rod and can move vertically to assist in controlling the punching depth.

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