Non-human primate individually ventilated cage environment-controlled housing apparatus

Abstract

The utility model belongs to non - human primates feeding equipment technical field discloses a kind of non - human primates independent ventilation cage environment control feeding equipment, comprising: independent ventilation cage and host connector, for connecting multifunctional host and cage;Independent ventilation cage exhaust hose, with the cage bottom side air outlet connection;Cage, its inside is sealed box, top is equipped with laminar flow plate and fan, bottom is equipped with stainless steel fecal support and excrement collection funnel, and 8 mobile wheels are installed;Multifunctional host, built-in filter system, steam hydrogen peroxide evaporator and sterile water conveying module are connected with the cage by air supply pipe, disinfection spray delivery pipe and sterile water pipe;The utility model, cage top is equipped with high-efficiency filter, vertical homogeneous airflow is formed in combination with laminar flow plate, coverage reaches 100%, significantly reduces the concentration of suspended particles and microorganisms in air. Independent air supply and exhaust system maintains negative pressure in cage, effectively isolates pathogen diffusion.

Description

Technical Field

[0001] This utility model relates to the technical field of non-human primate breeding equipment, and in particular to a non-human primate independent ventilation cage environmental control breeding equipment. Background Technology

[0002] Non-human primates (such as rhesus macaques and cynomolgus monkeys) have significant value in biomedical research and are widely used in vaccine development, drug screening, and disease model construction. However, traditional breeding equipment suffers from the following technical problems:

[0003] Existing cages mostly rely on a single filtration system or natural ventilation, which is insufficient to meet high cleanliness requirements, resulting in high concentrations of microorganisms in the air and increasing the risk of cross-infection. Chemical disinfectants (such as formaldehyde and ethylene oxide) require manual application, and residues may interfere with animal health and experimental data. Ultraviolet disinfection can only cover surface areas and cannot achieve complete sterilization.

[0004] Traditional manual cleaning methods are time-consuming and labor-intensive, and can easily expose operators to pathogens. The lack of automated processing systems also increases the risk of odor and bacterial growth. Frequent contact with animals or contaminants during the rearing process, coupled with insufficient glove seals and the potential for compromised airtightness during the opening and closing of glass doors, further increases biosafety risks. Utility Model Content

[0005] The main objective of this invention is to provide an environmental control and rearing device for non-human primates using independently ventilated cages. This addresses the shortcomings of existing cages that rely heavily on single filtration systems or natural ventilation, which fail to meet high cleanliness requirements, leading to high concentrations of microorganisms in the air and increasing the risk of cross-infection. Chemical disinfectants (such as formaldehyde and ethylene oxide) require manual operation, and residues may interfere with animal health and experimental data. Ultraviolet disinfection only covers surface areas and cannot achieve complete sterilization. Traditional manual cleaning methods are time-consuming and labor-intensive, easily exposing operators to pathogens. Furthermore, the lack of automated processing systems poses a high risk of odor and bacterial growth.

[0006] To achieve the aforementioned objectives, the first aspect of this utility model proposes an environmental control and rearing device for non-human primates using independently ventilated cages, comprising:

[0007] Independent ventilation cage and main unit connector, used to connect the multi-functional main unit and the cage;

[0008] An independent ventilation cage exhaust hose is connected to the air outlet on the side of the bottom of the cage.

[0009] The cage is a sealed box with a laminar flow plate and fan at the top, a stainless steel manure tray and manure collection funnel at the bottom, and is equipped with 8 casters.

[0010] The multi-functional main unit has a built-in filtration system, a steam hydrogen peroxide evaporator, and a sterile water delivery module, and is connected to the cage through an air supply pipe, a disinfection spray delivery pipe, and a sterile water pipe.

[0011] Steel-framed glass airtight cage door, equipped with pneumatic lock and glass viewing window;

[0012] The glove port and glove are located at the front of the cage for operator isolation during operation;

[0013] The sterile food inlet is connected to the sterile food buffer bin, and feeding is done through the cage mesh door;

[0014] The sewage pipe connects the feces collection funnel to an external vacuum pressurized sewage pumping system;

[0015] The cage is equipped with an independent cage mesh to form an independent cage frame, and a high-efficiency filter is installed on the top. Independent ventilation is achieved through fresh air and exhaust ducts.

[0016] Furthermore, the multi-functional host has two air inlets on both sides. The filtered fresh air enters the cage through the air supply pipe, is filtered twice by the laminar flow plate to form a clean airflow, and is then discharged through the bottom side air outlet to form an independent air supply and exhaust system.

[0017] Furthermore, the multi-functional host has a built-in hydrogen peroxide vaporizer, which delivers hydrogen peroxide vapor to the disinfection spray nozzle at the top of the cage through a disinfection spray delivery pipe to disinfect the inside of the cage. At the same time, a sensor is installed at the top of the cage to monitor the concentration of hydrogen peroxide vapor.

[0018] Furthermore, the multi-functional host delivers sterile water to the sterile water nozzle at the front end of the bottom of the cage through a sterile water pipe. The stainless steel manure tray is designed with a sloping structure so that the sterile water flows to the manure collection funnel at the rear end and is discharged through the sewage pipe via a vacuum pressurized manure pumping system.

[0019] Furthermore, the steel-glass sealed cage door is equipped with a pneumatic door lock, and the front of the cage body is provided with a sliding cage mesh door, with an operating space left between the cage body and the steel-glass sealed cage door, so as to facilitate feeding and simple operation with gloves.

[0020] A food box is installed on the cage door.

[0021] Furthermore, the cage is equipped with an LED lighting strip, an atomizing disinfection nozzle, and a constant temperature system. The lower isolation chamber contains a cleaning pressure water gun, a sterile feed storage box, a sterile water storage box, and a manure cleaning ditch arranged in sequence.

[0022] Furthermore, the fecal collection funnel is equipped with a liquid level sensor. When the water level rises to the discharge level, the sensor signal triggers the control unit to open the vacuum discharge valve, and the liquid in the buffer box is lifted to the vacuum pipeline and transmitted to the vacuum pump station through the pressure difference.

[0023] Furthermore, the combination of the high-efficiency filter and the laminar flow plate achieves two-stage filtration, meeting the requirements for a clean environment.

[0024] Furthermore, the glove is made of a corrosion-resistant material, and the glove port is sealed to the cage to prevent airflow leakage.

[0025] Furthermore, the casters are omnidirectional casters with brakes, which facilitates fixing the position of the cage.

[0026] Beneficial effects:

[0027] This utility model of an independent ventilated cage environment control feeding device for non-human primates has yielded beneficial results.

[0028] 1. In this invention, a high-efficiency filter is installed at the top of the cage, which, combined with a laminar flow plate, forms a vertical homogeneous airflow with 100% coverage, significantly reducing the concentration of suspended particles and microorganisms in the air. An independent air supply and exhaust system maintains negative pressure inside the cage, effectively isolating the spread of pathogens.

[0029] 2. This invention employs 30%-35% liquid hydrogen peroxide vaporization technology, uniformly distributing steam through a top spray nozzle, achieving a kill rate >99.9%, suitable for spores, viruses, and drug-resistant bacteria. An integrated sensor monitors VHP concentration in real time, automatically adjusting the dosage and linking with the ventilation system to eliminate residual risks, shortening the disinfection cycle to less than 30 minutes.

[0030] 3. In this invention, sterile water flows through a sloping stainless steel manure tray to a collection funnel at the rear end, periodically flushing and diluting the manure, reducing ammonia generation, and improving air quality. A liquid level sensor triggers a vacuum pumping system, enabling automatic discharge of manure to a central treatment station, reducing the risk of human contact with pollution sources, and increasing manure removal efficiency by more than 80%.

[0031] 4. This utility model links a sliding cage door with a robotic arm feeding system, and remotely dispenses feed through a sterile food buffer, reducing animal stress and improving operational safety by 90%. Attached Figure Description

[0032] Figure 1 This is a schematic diagram of the structure of an independent ventilation cage environmental control feeding device for non-human primates according to an embodiment of this utility model;

[0033] Figure 2 This is a front view schematic diagram of an embodiment of the non-human primate independent ventilation cage environmental control feeding equipment of this utility model;

[0034] Figure 3 This is a cross-sectional schematic diagram of an embodiment of the non-human primate independent ventilation cage environmental control feeding device of this utility model;

[0035] Figure 4 This is a cross-sectional schematic diagram of an embodiment of the non-human primate independent ventilation cage environmental control feeding equipment.

[0036] in:

[0037] 1-Independent ventilation cage and main unit connector; 2-Independent ventilation cage exhaust hose; 3-Cage body; 4-Multi-functional main unit; 5-Drainage pipe; 6-Steel glass sealed cage door; 7-Glove port; 8-Sterile food inlet; 9-Moving wheels; 10-Laminar flow plate; 11-Air outlet; 12-Independent cage mesh; 13-Air supply pipe; 14-Disinfectant spray delivery pipe; 15-Disinfectant spray nozzle; 16-Sterile water pipe; 17-Stainless steel manure tray; 18-Manure collection funnel; 19-Pneumatic door lock; 20-Glove; 21-Cage mesh door; 22-Sterile food buffer compartment; 24-Sterile water nozzle; 23-Air inlet; 25-Food box.

[0038] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0039] It should be understood that the specific embodiments described herein are merely illustrative of the present invention and are not intended to limit the present invention.

[0040] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of the stated features. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly and specifically defined.

[0041] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, a direct connection, or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0042] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0043] Example 1

[0044] Reference Figures 1-4 An embodiment of this utility model provides an environmental control and rearing device for non-human primates with independently ventilated cages, comprising:

[0045] Independent ventilation cage and main unit connector 1, used to connect the multi-functional main unit 4 and the cage body 3;

[0046] The independent ventilation cage exhaust hose 2 is connected to the air outlet 11 on the bottom side of the cage body 3;

[0047] The cage 3 has a sealed box inside, with a laminar flow plate 10 and a fan on the top, a stainless steel manure tray 17 and a manure collection funnel 18 on the bottom, and is equipped with 8 casters 9.

[0048] The multi-functional host 4 has a built-in filtration system, a steam hydrogen peroxide evaporator and a sterile water delivery module, and is connected to the cage 3 through an air supply pipe 13, a disinfection spray delivery pipe 14 and a sterile water pipe 16.

[0049] A steel-framed glass airtight cage door 6, equipped with a pneumatic door lock 19 and a glass viewing window;

[0050] Glove port 7 and glove 20 are located at the front of the cage 3 for operator isolation during operation;

[0051] The sterile food inlet 8 is connected to the sterile food buffer bin 22 and is fed through the cage mesh door 21;

[0052] Sewage pipe 5 connects the feces collection funnel 18 to an external vacuum pressurized feces pumping system;

[0053] The cage 3 is equipped with an independent cage mesh 12 to form an independent cage frame. A high-efficiency filter is installed on the top, and independent ventilation is achieved through fresh air and exhaust ducts. The multi-functional host 4 has two air inlets 23 on both sides. The filtered fresh air enters the cage 3 through the air supply duct 13, is filtered a second time by the laminar flow plate 10 to form a clean airflow, and is then discharged through the bottom side air outlet 11 to form an independent air supply and exhaust system.

[0054] The high-efficiency filter and the laminar flow plate 10 are combined to achieve two-stage filtration, meeting the requirements of a clean environment.

[0055] In this embodiment, the independent ventilation cage and the main unit connector 1 are quickly connected to the multi-functional main unit 4 through a quick-release interface to ensure the air supply pipe 13 and the independent ventilation cage exhaust hose 2 are sealed.

[0056] Multifunctional main unit 4: Built-in dual-stage filtration system, including a pre-filter and a high-efficiency filter with a filtration efficiency of ≥99.95%. Fresh air enters through the air inlets 23 on both sides, is filtered and pressurized, and then delivered to the air supply duct 13.

[0057] Laminar flow plate 10 and fan: A laminar flow plate 10 is installed on the top of the cage 3. The fan drives clean air to be evenly distributed, forming a vertical laminar airflow to avoid dust accumulation in dead corners.

[0058] Exhaust system: The bottom side air outlet 11 is connected to the laboratory exhaust main pipe through the independent ventilation cage exhaust hose 2 to ensure that the negative pressure in the cage is maintained at -15Pa to -30Pa.

[0059] Working principle: Fresh air is drawn in through the air inlet 23 of the main unit, large particulate impurities are removed by the pre-filter, and then purified into clean air by the high-efficiency filter.

[0060] Clean air is delivered into the cage 3 through the air supply duct 13, and the laminar flow plate 10 driven by the top fan forms a homogeneous airflow that covers the entire cage space.

[0061] Polluted air is discharged through the bottom air outlet 11, completing a closed-loop circulation and ensuring an air exchange rate of ≥15 times / hour inside the cage.

[0062] Beneficial effects: The dual-stage filtration system significantly reduces the concentration of microorganisms in the air, meeting the ABSL-3 laboratory cleanliness requirements. The laminar airflow design reduces particle deposition in the animal's breathing area, improving comfort. Negative pressure exhaust effectively isolates pathogens and prevents cross-contamination. Introducing laminar flow technology into non-human primate cages, combined with a modular air supply and exhaust design, achieves efficient air purification and dynamic pressure balance.

[0063] Example 2

[0064] In some embodiments, the multi-functional host 4 has a built-in hydrogen peroxide vaporizer, which delivers hydrogen peroxide vapor to the disinfection spray port 15 on the top of the cage 3 through the disinfection spray delivery pipe 14 and disinfects the inside of the cage 3. At the same time, a sensor is configured on the top of the cage 3 to monitor the concentration of hydrogen peroxide vapor.

[0065] It should be noted that the multi-functional host 4 has a built-in steam hydrogen peroxide evaporator, which converts 30%-35% liquid hydrogen peroxide into steam through a heating device, and then delivers it to the cage 3 through the disinfection spray delivery pipe 14.

[0066] The disinfection spray nozzle 15 is located at the top of the cage body 3, with multiple nozzles evenly distributed to ensure that steam covers all surfaces inside the cage.

[0067] Sensor monitoring system: A steam hydrogen peroxide concentration sensor is installed on the top of the cage to provide real-time data feedback to the main controller, which automatically adjusts the spraying time and dosage.

[0068] Working principle: After the main unit starts the disinfection program, liquid hydrogen peroxide is heated to 110℃ and vaporized, forming a high-concentration steam mixture. The steam is sprayed into the cage 3 through the disinfection spray nozzle 15, penetrating into the independent cage mesh 12, stainless steel manure tray 17, and the operating area, killing bacteria, viruses, and spores. Sensors monitor the VHP concentration inside the cage. When it reaches a set threshold, such as 800ppm, spraying stops, and ventilation mode is activated to expel residual gas.

[0069] Beneficial effects: VHP has an inactivation rate of >99.9% against spores, drug-resistant bacteria, and viruses, with no organic solvent residue. Automated monitoring and control ensure a safe and reliable disinfection process, reducing the risk of human intervention. The vacuum sewage system can simultaneously clean up disinfected waste, avoiding secondary pollution. Integrating the VHP disinfection system with vacuum sewage treatment achieves integrated "disinfection-cleaning" operation, meeting high biosafety requirements.

[0070] Example 3

[0071] In some embodiments, the multi-functional host 4 delivers sterile water to the sterile water nozzle 24 at the front end of the bottom of the cage 3 via a sterile water pipe 16. The stainless steel manure tray 17 is designed with a sloping structure, allowing the sterile water to flow to the manure collection funnel 18 at the rear end, and then be discharged through the sewage pipe 5 via a vacuum pressurized manure pumping system. The manure collection funnel 18 is equipped with a liquid level sensor. When the water level rises to the discharge level, the sensor signal triggers the control unit to open the vacuum discharge valve, and the liquid in the buffer box is lifted to the vacuum pipeline network and transmitted to the vacuum pump station through the pressure difference.

[0072] It should be noted that the sterile water pipe 16 connects to the sterile water storage tank of the multi-functional main unit 4, and delivers ultrapure water with a conductivity of <1μS / cm to the sterile water nozzle 24 at the front of the cage 3 via a pressure pump. The stainless steel manure tray 17 is designed with a slope structure that is lower at the front and higher at the back, with an inclination angle of 5°-8°, guiding the water flow to the manure collection funnel 18 at the rear. Vacuum pressurized manure pumping system: The sewage pipe 5 is connected to an external vacuum pipeline network. When the liquid level sensor detects that the water level in the manure collection funnel 18 has reached the warning line, it triggers the vacuum valve to open.

[0073] Working principle: Sterile water is periodically sprayed onto the stainless steel feces tray 17, diluting the feces and forming a liquid mixture, which flows by gravity to the feces collection funnel 18. A level sensor detects water level changes via a pressure sensor, transmitting the signal to the control unit, which then activates a vacuum pump to extract the liquid to the central treatment station. The system supports timed flushing and emergency discharge modes to ensure timely removal of feces.

[0074] Beneficial effects: The sterile water supply system reduces ammonia concentration in urine, improving air quality within the cages. Vacuum suction enables automated cleaning, reducing the risk of human contact with contaminants. The slope design optimizes liquid flow paths, preventing clogging issues.

[0075] By linking sterile water supply with vacuum manure treatment and combining it with slope structure design, a closed-loop cleaning system is constructed to improve the level of animal husbandry hygiene.

[0076] Example 4

[0077] In some embodiments, the steel-glass sealed cage door 6 is equipped with a pneumatic door lock 19 and a glass viewing window; a glove port 7 and a glove 20 are provided at the front of the cage body 3 for operator isolation; the steel-glass sealed cage door 6 is equipped with a pneumatic door lock 19, and a sliding cage mesh door 21 is provided at the front of the cage body 3, with an operating space between it and the steel-glass sealed cage door 6, facilitating feeding and simple operation through the gloves 20; a sterile food inlet 8 is connected to a sterile food buffer bin 22, and feeding is done through the cage mesh door 21; a food box 25 is provided on the cage mesh door 21.

[0078] It should be noted that the steel-glass sealed cage door 6 is equipped with a pneumatic door lock 19, ensuring a completely airtight barrier when the door is closed. The glove port 7 and glove 20 are embedded in the front of the cage body 3, made of butyl rubber, which is corrosion-resistant and has strong sealing properties, allowing operators to wear gloves 20 for feeding or inspection. The sliding cage door 21 is located inside the glass door and is linked to the aseptic food inlet 8, supporting remote robotic arm feeding. The aseptic food buffer compartment 22 is connected to the outside via an airlock, where food is temporarily stored after being irradiated with ultraviolet light to prevent contamination.

[0079] Operating principle: Routine operations are completed through the glove port 7, eliminating the need for direct contact between the operator and the internal environment of the cage 3. During food feeding, the cage door 21 opens, and the robotic arm delivers sterile feed from the sterile food buffer 22 into the food container 25. Surgical examinations require the temporary opening of the steel-glass sealed cage door 6; after the airlock is released, the door rotates 180° to ensure negative pressure is maintained throughout the operation.

[0080] Beneficial effects: The multi-mode operation design reduces animal stress and improves the accuracy of experimental data. The pneumatic lock and sealed gloves work synergistically to ensure operator biosafety. The remote feeding system reduces labor costs and adapts to the needs of large-scale animal husbandry.

[0081] By combining pneumatic door locks, gloves, and remote robotic arms, a "zero-exposure" operating procedure is achieved, breaking through traditional isolation limitations.

[0082] Example 5: Intelligent Control of Mobile Feeding Units and Environmental Parameters

[0083] In some embodiments, the caster wheel 9 is a universal caster wheel with brakes to facilitate fixing the position of the cage. The cage body 3 is equipped with an LED lighting strip, an atomizing disinfection nozzle and a constant temperature system, and the lower isolation cavity contains a cleaning pressure water gun, a sterile feed storage tank, a sterile water storage tank and a manure cleaning ditch arranged in sequence.

[0084] 9. Casters: 8 swivel casters with brakes, load capacity ≥200kg, anti-slip coating adaptable to various ground surfaces. Temperature Control System: Cage 3 incorporates a PTC heating film and semiconductor cooling module, temperature adjustable from 20-30℃ with fluctuation ≤±1℃. Environmental Monitoring Module: Integrates temperature and humidity sensors, a CO2 sensor, and a differential pressure gauge; data is uploaded to the central control system. LED Lighting Strip: Simulates a natural light cycle of 12h light / 12h darkness, promoting stable circadian rhythms in animals.

[0085] Operating principle: The 9-wheel system allows for rapid transfer of the cage to different experimental areas; after braking and locking, the cage is fixed in position via a foot switch. The temperature control system dynamically adjusts the heating / cooling power based on sensor data to maintain an optimal thermal environment. The central control system records environmental parameters and generates daily reports; in case of abnormalities, it triggers audible and visual alarms to indicate maintenance needs.

[0086] Beneficial effects: The mobile design improves laboratory space utilization and adapts to multi-tasking needs. The intelligent control system ensures long-term stability of the rearing environment, reducing the risk of disease in animals caused by environmental fluctuations. The data recording function meets GMP / GAP compliance requirements and facilitates quality traceability.

[0087] By integrating mobility, intelligent environmental control, and data management, a "plug-and-play" feeding unit is created, adaptable to complex experimental scenarios.

[0088] The above description is only a preferred embodiment of the present utility model and does not limit the patent scope of the present utility model. Any equivalent structural or procedural transformations made based on the content of the present utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of the present utility model.

Claims

1. A non-human primate independent ventilation cage environmental control feeding device, characterized in that, include: Independent ventilation cage and main unit connector (1) for connecting the multi-functional main unit (4) and the cage body (3); An independent ventilation cage exhaust hose (2) is connected to the bottom side air outlet (11) of the cage body (3); The cage (3) has a sealed box inside, with a laminar flow plate (10) and a fan on the top, a stainless steel manure tray (17) and a manure collection funnel (18) at the bottom, and is equipped with 8 casters (9). The multi-functional host (4) has a built-in filtration system, a steam hydrogen peroxide evaporator and a sterile water delivery module, and is connected to the cage (3) through an air supply pipe (13), a disinfection spray delivery pipe (14) and a sterile water pipe (16). A steel-framed glass-sealed cage door (6) is equipped with a pneumatic door lock (19) and a glass viewing window; The glove port (7) and glove (20) are located at the front of the cage (3) for operator isolation operation; The sterile food inlet (8) is connected to the sterile food buffer bin (22) and is fed through the cage door (21); The sewage pipe (5) is connected to the fecal collection funnel (18) and the external vacuum pressurized sewage pumping system; The cage (3) is equipped with an independent cage net (12) to form an independent cage frame. A high-efficiency filter is configured on the top, and independent ventilation is achieved through fresh air and exhaust pipes.

2. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The multi-functional host (4) has two air inlets (23) on both sides. After filtration, the fresh air enters the cage (3) through the air supply pipe (13), and after secondary filtration by the laminar flow plate (10), it forms a clean airflow, and then is discharged through the bottom side air outlet (11) to form an independent air supply and exhaust system.

3. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The multi-functional host (4) has a built-in hydrogen peroxide vaporizer. It delivers hydrogen peroxide vapor to the disinfection spray port (15) at the top of the cage (3) through the disinfection spray delivery pipe (14) and disinfects the inside of the cage (3). At the same time, the top of the cage (3) is equipped with a sensor to monitor the concentration of hydrogen peroxide vapor.

4. The environmental control and rearing equipment for non-human primates with independently ventilated cages according to claim 1, characterized in that, The multi-functional host (4) delivers sterile water to the sterile water nozzle (24) at the front end of the bottom of the cage (3) through the sterile water pipe (16). The stainless steel manure tray (17) is designed with a slope structure so that the sterile water flows to the manure collection funnel (18) at the rear end and is discharged through the sewage pipe (5) by the vacuum pressurized manure pumping system.

5. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The steel glass sealed cage door (6) is equipped with a pneumatic door lock (19). The front of the cage body (3) is provided with a sliding cage mesh door (21), and there is an operating space between it and the steel glass sealed cage door (6), so that feeding and simple operation can be completed by using gloves (20). A food box (25) is provided on the cage door (21).

6. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The cage (3) is equipped with an LED lighting strip, an atomizing disinfection nozzle and a constant temperature system. The lower isolation chamber contains a cleaning pressure water gun, a sterile feed storage box, a sterile water storage box and a manure cleaning ditch arranged in sequence.

7. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The fecal collection funnel (18) is equipped with a liquid level sensor. When the water level rises to the discharge level, the sensor signal triggers the control unit to open the vacuum discharge valve. The liquid in the buffer box is then lifted to the vacuum pipeline and transmitted to the vacuum pump station through the pressure difference.

8. The non-human primate independent ventilated cage environmental control feeding equipment according to claim 1, characterized in that, The high-efficiency filter and the laminar flow plate (10) are combined to achieve two-stage filtration, meeting the requirements of a clean environment.

9. The environmental control and rearing equipment for non-human primates with independent ventilation cages according to claim 1, characterized in that, The glove (20) is made of corrosion-resistant material, and the glove port (7) is sealed to the cage (3) to prevent airflow leakage.

10. The environmental control and rearing equipment for non-human primates with independently ventilated cages according to claim 1, characterized in that, The movable wheel (9) is a universal wheel with brakes, which makes it easy to fix the position of the cage.

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