Biological sample analysis apparatus and reagent storage device
By designing detachable detection components and reagent kits in blood gas analyzers, the connection and separation of liquid circuits can be achieved, solving the problems of low analysis efficiency and inconvenient replacement of consumables caused by unreasonable equipment structure, and improving the detection efficiency and maintenance convenience of the equipment.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- EDAN INSTR
- Filing Date
- 2023-07-17
- Publication Date
- 2026-06-16
Smart Images

Figure CN224366050U_ABST
Abstract
Description
[0001] This application claims priority to Chinese Patent Application No. 202210912914.X, filed on July 31, 2022, entitled “Reagent Kit, Detection Components and Blood Gas Analysis Device”, the entirety of which is incorporated herein by reference. Technical Field
[0002] This application relates to the field of sample analysis technology, specifically to a reagent kit, a detection component, and a blood gas analysis device. Background Technology
[0003] Blood gas analysis is the process of using blood gas analysis equipment to test blood samples to obtain biochemical parameters.
[0004] Blood gas analysis requires cleaning and calibration of the equipment to prevent interference between different blood samples. Furthermore, the liquid containers used for cleaning and calibration, as well as the fluid piping used in the analysis process, are mostly consumables and need to be replaced after a certain period or number of uses. Therefore, optimizing the layout of the blood gas analysis equipment to improve its analytical efficiency is a pressing technical issue that needs to be addressed. Summary of the Invention
[0005] This application aims to provide a reagent kit, detection components, and blood gas analysis equipment to address the technical shortcomings of blood gas analysis equipment with an unreasonable structure.
[0006] This application provides a blood gas analysis device, including a first detection component and a reagent kit. The first detection component has a detection element, a first liquid path, and a first interface. The first liquid path and the first interface are connected. The detection element is used to perform blood gas detection on the liquid in the first liquid path. The reagent kit has a cavity, a second liquid path, and a second interface. The cavity is used to hold a liquid bag. One end of the second liquid path is connected to the liquid bag, and the other end is connected to the second interface. The first detection component and the reagent kit can be docked or detached, such that the first interface and the second interface are connected or detached. When connected, the first liquid path connects to the second liquid path so that the reagent in the liquid bag can reach the first liquid path. When the reagent kit is moved into the mounting bracket of the blood gas analysis device, the first interface and the second interface are connected.
[0007] This application provides a detection component, including a housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element; wherein the first liquid path and the first interface are in communication, the detection element is used to perform blood gas detection on the liquid in the first liquid path, the first interface is used to dock with or detach from a second interface of a reagent kit, so that when docking, the reagent of the reagent kit can be obtained through the first interface, and when docking, the connection terminal is used to be electrically connected to the processing circuit of a blood gas analysis device.
[0008] This application provides a reagent kit, including a cavity, a second liquid passage, and a second interface; wherein, the cavity is used to hold a liquid package, one end of the second liquid passage is used to connect to the liquid package, and the other end is used to connect to the second interface, the second interface is used to dock with or detach from a first interface of a first detection component, so that when docking, the reagent in the liquid package is delivered to the first detection component through the second interface; the reagent kit can be moved into or out of the mounting bracket of a blood gas analysis device, and when the reagent kit is moved into, the first interface and the second interface are connected.
[0009] This application provides a blood gas analysis device, including a mounting bracket with a first mounting position and a second mounting position. The first mounting position is used for detachably mounting a first detection component, and the second mounting position is used for placing a reagent kit. The first detection component and the reagent kit can be docked or detached, so that the first detection component and the reagent kit are connected or disconnected. When connected, the reagent in the reagent kit can reach the first detection component.
[0010] The blood gas analysis device provided in this application embodiment allows for the docking or detachment of the first detection component and the reagent kit, enabling detachable assembly and disassembly. During docking, the first liquid path of the first detection component communicates with the second liquid path of the reagent kit, allowing the reagents from the reagent kit to reach the first liquid path for blood gas detection. Furthermore, by providing a mounting bracket for assembling the reagent kit and the first detection component, and enabling docking or detachment of the first detection component and the reagent kit upon assembly, and allowing the reagent kit to be individually disassembled and replaced during detachment, detection efficiency can be improved.
[0011] This application provides an adjustment device for use in a liquid sample detection device, including a first adjustment component and a second adjustment component; wherein, the first adjustment component is used to adjust the rotation angle of a sampling element relative to the liquid sample detection device to switch between a first fluid path and a second fluid path for conveying liquid; the second adjustment component is used to adjust the axial position of a sleeve sleeved on the sampling element to switch between a first position and a second position; when the sleeve is in the first position, the sampling element can achieve connectivity of the first fluid path; when the sleeve is in the second position, the first adjustment component can adjust the rotation angle of the sampling element to achieve connectivity of the second fluid path.
[0012] This application provides a liquid sample detection device, comprising: a body having a first mounting position; and an adjustment device mounted at the first mounting position; wherein the adjustment device comprises: a first adjustment component and a second adjustment component; the first adjustment component is used to adjust the rotation angle of a sampling element relative to the body to switch between a first fluid path and a second fluid path for conveying liquid; the second adjustment component is used to adjust the axial position of a sleeve sleeved on the sampling element to switch between a first position and a second position; when the sleeve is in the first position, the sampling element can achieve connectivity of the first fluid path; when the sleeve is in the second position, the first adjustment component can adjust the rotation angle of the sampling element to achieve connectivity of the second fluid path.
[0013] The adjustment device provided in this application embodiment adjusts the rotation angle of the sampling element through the first adjustment component and adjusts the axial position of the sleeve sleeved on the sampling element through the second adjustment component, so that the sampling element can switch between the first fluid path and the second fluid path, which can simply and reliably meet the needs of switching different sampling fluid paths.
[0014] This application provides a biological tissue detection framework, comprising: a plurality of plates interconnected to form a cavity and a first mounting position, the first mounting position for mounting a biological tissue measurement platform, and the cavity for accommodating auxiliary consumables; wherein, a clearance channel is provided between the cavity and the first mounting position, the clearance channel for avoiding mechanical docking operations and consumable delivery paths between the biological tissue measurement platform and the auxiliary consumables, the consumable delivery path being a passage connecting a first conduit of the biological tissue measurement platform and a second conduit of the auxiliary consumables.
[0015] This application provides a biological tissue detection device, comprising: a biological tissue frame having a cavity and a first mounting position; a biological tissue measurement platform detachably mounted on the first mounting position and having a first conduit; and an auxiliary consumable capable of being moved into or out of the cavity and having a second conduit; wherein, a clearance channel is provided between the cavity and the first mounting position, the clearance channel being used to avoid mechanical docking operations between the biological tissue measurement platform and the auxiliary consumable and the consumable delivery path, the consumable delivery path being a passage connecting the first conduit and the second conduit.
[0016] The biological tissue detection framework provided in this application embodiment enables mechanical docking and consumable delivery between the auxiliary consumables in the cavity and the biological tissue measurement platform on the first mounting position by setting an obstacle avoidance channel between the cavity and the first mounting position. The structure is simple.
[0017] This application provides a sample analysis device, comprising: a fixed base and a mounting base, with a guide rod disposed between the fixed base and the mounting base; a conveying assembly disposed between the fixed base and the mounting base, and the conveying assembly being sleeved on the guide rod and slidable along the guide rod; and a testing assembly disposed between the fixed base and the mounting base, and the testing assembly being sleeved on the guide rod and slidable along the guide rod; wherein the testing assembly is disposed on the side of the conveying assembly opposite to the fixed base, a first elastic element is disposed between the conveying assembly and the fixed base to allow the conveying assembly and the fixed base to be separated by the first elastic element; and a second elastic element is disposed between the conveying assembly and the testing assembly to allow the conveying assembly and the testing assembly to be separated by the second elastic element.
[0018] The sample analysis device provided in this application embodiment enables the conveying component and the fixed base to be separated by setting a first elastic element, and enables the conveying component and the testing component to be separated by setting a second elastic element. That is, when the sample analysis device completes the analysis operation, there is no need to set other driving mechanisms. The separation of the conveying component and the fixed base, as well as the separation of the conveying component and the testing component, can be achieved by the first elastic element and the second elastic element. The overall structure is simple.
[0019] This application provides a biological detection device, including: a first base and a second base; a guide member located between the first base and the second base and extending in the arrangement direction of the first base and the second base; a test component disposed on the guide member and movable along the guide member; a transmission component mounted on the first base, the transmission component including a drive member; wherein, the test component has a top holding member on the side near the first base, and the drive member and the top holding member roll in cooperation to drive the test component to move along the guide member.
[0020] The biological detection device provided in this application embodiment can ensure the stability of the movement of the test component by setting a top support and a driving component in a rolling cooperation on the detection component to drive the test component to move along the guide rod, and can move the test component to a preset position for corresponding testing.
[0021] This application provides a blood sample analysis platform, comprising: a blood sample analyzer having a non-contact detection element and a clearance tank; an auxiliary liquid container having a cavity and a liquid path, the cavity being used to hold an auxiliary liquid and a waste liquid bag, one end of the liquid path being used to input the auxiliary liquid and the other end being used to connect to the waste liquid bag; wherein, the liquid path has a portion exposed outside the auxiliary liquid container, and the non-contact detection element is used to detect the portion entering the clearance tank.
[0022] This invention provides a blood sample analyzer, comprising: a test seat and a non-contact detection element, wherein the test seat is provided with a clearance groove; the non-contact detection element is connected to the test seat and is used to detect liquid entering the clearance groove; wherein the test seat is used to dock with or detach from an auxiliary liquid container, and the liquid path of the auxiliary liquid container has a curved portion protruding from the auxiliary liquid container; when the test seat and the auxiliary liquid container dock, the curved portion enters the clearance groove to be detected by the non-contact detection element.
[0023] This application provides an auxiliary liquid cartridge, including: a cavity and a liquid passage; wherein, the cavity is used to hold an auxiliary liquid and a waste liquid pack, one end of the liquid passage is used to input the auxiliary liquid, and the other end is used to connect to the waste liquid pack; the liquid passage has a portion exposed outside the auxiliary liquid cartridge, which enters the clearance groove of the blood pressure analyzer when the auxiliary liquid cartridge is docked with the blood sample analyzer, so as to be detected by the non-contact detection element of the blood sample analyzer.
[0024] The blood sample analysis platform provided in this application exposes the liquid path portion of the auxiliary liquid box outside the auxiliary liquid box, and when this portion enters the clearance slot of the blood sample analyzer, the non-contact detection element of the blood sample analyzer can detect this portion, thereby realizing non-contact detection of liquid in the liquid path.
[0025] This application provides a fluid detection instrument, comprising: a valve assembly having a control element, a first pipe, an inlet, and an outlet, wherein the number of inlets is plurality of, and the control element is used to control one of the plurality of inlets to communicate with one end of the first pipe, and the other end of the first pipe to communicate with the outlet; a fluid box having a cavity and an interface, the cavity being used to hold a fluid package, one end of the interface being used to communicate with the fluid package, and the other end being used to communicate with the inlet; wherein the valve assembly and the fluid box can be connected or separated, such that the inlet and the interface are connected or separated, and when connected, the first pipe can be connected to the interface under the control of the control element, so that the fluid in the fluid package can reach the first pipe.
[0026] This application provides a valve assembly, including: a control element, a first pipe, an inlet, and an outlet; wherein, the number of inlets is plurality of, and the control element is used to control one of the plurality of inlets to communicate with one end of the first pipe, and the other end of the first pipe to communicate with the outlet; the inlet is used to dock or disconnect with an interface of a fluid box, so that when docking, the control element controls the inlet to obtain fluid from the fluid box.
[0027] This application provides a fluid box, including: a cavity and an interface; wherein, the cavity is used to hold a fluid pack, one end of the interface is used to connect to the fluid pack, and the other end is used to connect to the inlet of a valve assembly; the valve assembly and the fluid box can be docked or separated, so that when docked, the fluid in the fluid box can be transported to the valve assembly through the interface.
[0028] The fluid detection instrument provided in this application embodiment allows for the docking or disassembly of the valve assembly and fluid housing, enabling detachable assembly and disassembly of the fluid housing and valve assembly. During docking, the control element of the valve assembly controls the interface between the first pipe of the valve assembly and the fluid housing, allowing the liquid in the fluid housing to reach the first pipe for detection. Furthermore, the control element can control one of several inlets to connect to the first pipe, facilitating the selection of the liquid flowing into the first pipe.
[0029] This application provides an integrated reagent kit, comprising: a housing having a receiving space for storing a reagent pack and a return pack; a sampling device disposed on the housing and located outside the receiving space; a first conduit and a second conduit disposed on the housing; wherein the input end of the sampling device is connected to the reagent pack through the first conduit, and the output end of the sampling device is connected to the return pack through the second conduit; the sampling device is rotatable relative to the housing so that the input end of the sampling device can collect liquid from the reagent pack or an external container.
[0030] The integrated reagent kit provided in this application embodiment, through a sampling device, a first pipe, and a second pipe set on the box body, enables the sampling device to collect liquid from the reagent pack through the first pipe, and the liquid from the sampling device to reach the recovery pack through the second pipe; in addition, by setting the sampling device to be rotatable relative to the box body, the sampling device can collect liquid from external containers or reagent packs, improving the diversity of liquids collected by the sampling device and the flexibility of the reagent kit.
[0031] This application provides a reagent storage device, comprising: a storage box, a sampling component and a docking component disposed on the storage box and located outside the storage box; wherein, the outlet end of the sampling component is connected to a first position inside the storage box, and the docking component is provided with a sampling groove, the sampling groove being connected to a second position inside the storage box; the sampling component and the docking component can be connected or separated; when the sampling component and the docking component are connected, the inlet end of the sampling component is inserted into the sampling groove to take a sample from the second position inside the storage box; when the sampling component and the docking component are separated, the inlet end can take a sample from outside the storage box.
[0032] The reagent storage device provided in this application embodiment uses a sampling component and a docking component mounted on the storage box to cooperate, allowing the sampling component to take samples from inside or outside the storage box. Specifically, when the sampling component and the docking component are docked, the inlet end of the sampling component is inserted into the sampling groove of the docking component to take samples from inside the storage box; when the sampling component and the docking component are separated, the inlet end of the sampling component can take samples from outside the storage box. That is, the above-described structure of this application embodiment allows for flexible rotation of the sampling position of the sampling component and allows for reasonable allocation of the quantity and type of liquid in the storage box.
[0033] This application provides a liquid parameter measurement platform, comprising: a liquid loading box having a liquid collection component and an adjustment component; wherein the adjustment component is configured to be driven by an external force to rotate the liquid collection component relative to the liquid loading box by an angle; a rotation component and a moving component; wherein the rotation of the rotation component synchronously drives the moving component to rotate, and the moving component is movable relative to the rotation component; wherein the adjustment component and the rotation component can be docked or separated, and when the adjustment component and the rotation component are docked, the rotation component can drive the adjustment component to rotate relative to the liquid loading box, thereby driving the liquid collection component to rotate relative to the liquid loading box; the liquid collection component and the moving component can follow the docking or separation of the adjustment component and the rotation component to achieve corresponding docking or separation, and when the liquid collection component and the moving component are docked, the moving component is used to adjust at least a portion of the axial position of the liquid collection component so that the rotation component can drive the liquid collection component to switch between a first posture and a second posture; the first posture corresponds to limiting the liquid collection component to collect liquid inside the liquid loading box, and the second posture corresponds to limiting the liquid collection component to collect liquid outside the liquid loading box.
[0034] This application provides a liquid loading box for use in a liquid parameter measurement platform, comprising: a liquid sampling component and an adjustment component. The adjustment component is configured to be driven by an external force to rotate the liquid sampling component relative to the liquid loading box by an angle. The adjustment component is used to dock with or separate from a rotating component. When the adjustment component and the rotating component are docked, the rotating component can drive the adjustment component to rotate relative to the liquid loading box, thereby causing the liquid sampling component to rotate relative to the liquid loading box. The liquid sampling component is used to dock with or separate from a moving component. The liquid sampling component and the moving component can follow the docking or separation of the adjustment component and the rotating component to achieve corresponding docking or separation. When the liquid sampling component and the moving component are docked, the moving component can adjust at least a portion of the axial position of the liquid sampling component, so that the rotating component can drive the liquid sampling component to switch between a first state and a second state. The first posture corresponds to limiting the liquid sampling component to collect liquid inside the liquid loading box, and the second posture corresponds to limiting the liquid sampling component to collect liquid outside the liquid loading box.
[0035] This application provides a motion device for a liquid parameter measurement platform, comprising: a rotating component and a moving component. The rotating component rotates synchronously, driving the moving component to rotate as well. The moving component is movable relative to the rotating component. The rotating component is used to dock with or disengage from an adjustment component of a liquid loading container. When the rotating component and the adjustment component are docked, the rotating component drives the adjustment component to rotate relative to the liquid loading container, thereby causing a liquid-collecting component of the liquid loading container to rotate relative to the liquid loading container. The moving component is used to dock with or disengage from the liquid-collecting component. The moving component and the liquid-collecting component can follow the docking or disengagement of the adjustment component and the rotating component to achieve corresponding docking or disengagement. When the liquid-collecting component and the moving component are docked, the moving component adjusts at least a portion of the axial position of the liquid-collecting component, enabling the rotating component to drive the liquid-collecting component to switch between a first posture and a second posture. The first posture corresponds to limiting the liquid-collecting component to collect liquid inside the liquid loading container, and the second posture corresponds to limiting the liquid-collecting component to collect liquid outside the liquid loading container.
[0036] The liquid parameter measurement platform provided in this application embodiment allows for the docking or disengagement of an adjustment component and a rotation component. During docking, the rotation component drives the adjustment component to rotate relative to the liquid loading box, thereby causing the liquid sampling component to rotate relative to the liquid loading box. Furthermore, the liquid sampling component and a moving component are designed to dock or disengage in tandem with the adjustment and rotation components. During docking, the moving component can adjust at least a portion of the axial position of the liquid sampling component, enabling the rotation component to switch the liquid sampling component between a first posture and a second posture. The first posture corresponds to the limiting liquid sampling component collecting liquid inside the liquid loading box, while the second posture corresponds to the limiting liquid sampling component collecting liquid outside the liquid loading box. This structural design allows for flexible adjustment of the liquid sampling posture of the liquid sampling component and enriches the diversity of liquid parameter measurement platform detection capabilities.
[0037] This application provides a biological sample analysis device, including: a drive assembly with an output shaft; a reagent storage device with a storage cavity, a connecting pipe, and a squeezing assembly, wherein the storage cavity is used to place a reagent pack and a recovery pack, and the connecting pipe is partially embedded in the squeezing assembly; one end of the connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recovery pack; wherein the drive assembly and the reagent storage device can be docked or separated, so that the output shaft can dock or separate from the squeezing assembly; when docked, the output shaft can drive the squeezing assembly to squeeze the connecting pipe so that the liquid in the connecting pipe can flow.
[0038] This application provides a reagent storage device, including: a storage cavity, a connecting pipe, and a squeezing assembly; wherein, the storage cavity is used to place a reagent pack and a recycling pack, and the connecting pipe is partially embedded in the squeezing assembly; one end of the connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recycling pack; the squeezing assembly is used to dock with or disengage from the output shaft of a drive assembly, so that when docking, the output shaft drives the squeezing assembly to squeeze the connecting pipe so that the liquid in the connecting pipe can flow.
[0039] The biological sample analysis device provided in this application embodiment can be docked or separated to achieve detachable assembly of the drive component and the reagent storage device. When docked, the output shaft of the drive component can drive the squeezing component on the reagent storage device to squeeze the connecting pipe so that the liquid in the connecting pipe can flow. There is no need to set an additional drive device to drive the liquid flow in the reagent storage device, and the detachable assembly of the drive component and the reagent storage device makes it easy to replace.
[0040] This application provides a liquid-driven device, including: a power component, a rotating component, and a liquid pipe; one of the power component and the rotating component has a rotating shaft, and the other has a mating portion into which the rotating shaft can be inserted; one of the rotating shaft and the mating portion is provided with a snap-fit element, and the other is provided with a snap-fit groove; the liquid pipe is disposed within the rotating component, and the rotation of the rotating component can compress the liquid pipe; wherein, the power component and the rotating component can be docked or separated, so that the rotating shaft is inserted into or pulled out of the mating portion; when the rotating shaft is inserted into the mating portion, the rotating shaft can rotate to achieve engagement and limiting of the snap-fit element and the snap-fit groove.
[0041] This application provides a reagent kit, comprising: a receiving cavity, a liquid tube, and a rotating assembly; wherein, the receiving cavity is used to hold a reagent pack and a recovery pack, the liquid tube is disposed within the rotating assembly, and rotation of the rotating assembly can squeeze the liquid tube so that liquid in the reagent pack can reach the recovery pack via the liquid tube; the rotating assembly is used to dock or disengage with a power assembly, one of the power assembly and the rotating assembly having a rotating shaft, and the other having a mating part into which the rotating shaft can be inserted; one of the rotating shaft and the mating part is provided with a locking element, and the other with a locking groove; when the rotating assembly docks with the power assembly, the rotating shaft is inserted into the mating part, and the rotating shaft can be rotated to achieve engagement and limiting of the locking element and the locking groove.
[0042] This application provides a sample analysis device, comprising: a mounting bracket having a first mounting position and a second mounting position, the first mounting position being used to mount a reagent kit, and the second mounting position being used to mount a power component; wherein the power component is used to dock or detach from a rotating component of the reagent kit, one of the power component and the rotating component having a rotating shaft, and the other having a mating part into which the rotating shaft can be inserted; one of the rotating shaft and the mating part having a locking element, and the other having a locking groove; when the rotating component docks with the power component, the rotating shaft is inserted into the mating part, and the rotating shaft can be rotated to achieve engagement and limiting of the locking element and the locking groove.
[0043] The liquid drive device provided in this application embodiment provides a snap-fit element on one of the rotating shaft and the mating part, and a snap-fit groove on the other. By rotating the rotating shaft, the snap-fit element and the snap-fit groove can be engaged and limited. It is not necessary to align the snap-fit element and the snap-fit groove when assembling the rotating shaft and the mating part. That is, after the rotating shaft and the mating part are assembled, rotating the rotating shaft can achieve the engagement and limitation of the snap-fit element and the snap-fit groove, thereby improving assembly efficiency.
[0044] This application provides a medical testing device, comprising: a testing component having a detection element, a first liquid path, and a first interface, wherein the first liquid path and the first interface are connected, and the detection element is used to detect the liquid in the first liquid path to obtain a detection signal; a processing circuit detachably connected to the detection element of the testing component, used to receive the detection signal when the detection element is connected; and a reagent kit having a cavity, a second liquid path, and a second interface, wherein the cavity is used to hold a liquid bag, one end of the second liquid path is used to connect to the liquid bag, and the other end is connected to the second interface; wherein the testing component and the reagent kit can be docked or detached, such that the first interface and the second interface are connected or detached, wherein when connected, the first liquid path connects to the second liquid path so that the reagent in the liquid bag can reach the first liquid path; and, when the testing component and the reagent kit are detached to replace the reagent kit, the processing circuit remains electrically connected to the detection element of the testing component.
[0045] This application provides a detection component, including: a housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element; wherein, the first liquid path and the first interface are in communication, the detection element is used to perform blood gas detection on the liquid in the first liquid path to obtain a detection signal, the first interface is used to dock with or detach from a second interface of a reagent kit, so that when docking, the reagent of the reagent kit can be obtained through the first interface; and, when the detection component and the reagent kit are detached to replace the reagent kit, the connection terminal remains electrically connected to the processing circuit of the medical testing device.
[0046] This application provides a reagent kit, comprising: a cavity, a second liquid path, and a second interface; wherein, the cavity is used to hold a liquid pack, one end of the second liquid path is connected to the liquid pack, and the other end is connected to the second interface, the second interface is used to dock with a first interface of a detection component when the reagent kit is used for detection, so that the reagent in the liquid pack is delivered to the detection component through the second interface during docking, and the second interface is detached from the detection component before the reagent kit is used for detection; the reagent kit is movable into or out of the mounting bracket of a medical testing device, and when the reagent kit is moved in, the first interface and the second interface are connected.
[0047] This application provides a medical testing device, comprising: a mounting bracket having a first mounting position, a second mounting position, and a third mounting position, wherein the first mounting position is used to mount a testing component, and the second mounting position is used to mount a reagent kit; and a processing circuit disposed at the third mounting position and detachably connected to the testing component; wherein the testing component and the reagent kit can be docked or detached, such that the testing component and the reagent kit are connected or disconnected, wherein when connected, the reagent in the reagent kit can reach the testing component; and, when the testing component and the reagent kit are separated to replace the reagent kit, the processing circuit remains electrically connected to the testing component.
[0048] The medical testing device provided in this application embodiment allows the testing component and the reagent kit to be docked or detached, so that when the first interface and the second interface are connected, the first liquid path is connected to the second liquid path, allowing the reagent in the liquid package to reach the first liquid path for testing; and when the testing component and the reagent kit are separated to replace the reagent kit, the processing circuit maintains an electrical connection with the detection element of the testing component, so as to avoid the processing circuit and the detection element losing power and affecting the continuity of subsequent testing and the accuracy of the test data.
[0049] This application provides a medical testing device, comprising: a testing component having a detection element, a first liquid path, and a first interface, wherein the first liquid path and the first interface are connected, and the detection element is used to detect the liquid in the first liquid path to obtain a detection signal; a reagent kit having a cavity, a second liquid path, and a second interface, wherein the cavity is used to hold a liquid bag, one end of the second liquid path is used to connect to the liquid bag, and the other end is connected to the second interface; and a processing circuit detachably connected to the detection element of the testing component, used to receive the detection signal when the detection element is connected; wherein when the processing circuit and the detection element are disassembled, the testing component can be disassembled synchronously with the reagent kit; wherein the testing component is detachably mounted on the reagent kit such that the first interface and the second interface are connected or disconnected, and when connected, the first liquid path connects to the second liquid path so that the reagent in the liquid bag can reach the first liquid path.
[0050] This application provides a detection component, including: a housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element; wherein the first liquid path and the first interface are in communication, the detection element is used to detect the liquid in the first liquid path to obtain a detection signal, the first interface is used to dock with or detach from a second interface of a reagent kit, so that the reagent of the reagent kit can be obtained through the first interface when docking; and the detection component is used to be mounted on the reagent kit, and the connection terminal is used to be electrically connected to the processing circuit of the medical testing device.
[0051] This application provides a reagent kit, comprising: a cavity, a second liquid path, and a second interface; wherein, the cavity is used to hold a liquid pack, one end of the second liquid path is connected to the liquid pack, and the other end is connected to the second interface, the second interface is used to dock with a first interface of a detection component when the reagent kit is used for detection, so that the reagent in the liquid pack is delivered to the detection component through the second interface during docking; and, the detection component is detachably mounted on the reagent kit, and when the reagent kit is disassembled, the detection component can be disassembled synchronously with the reagent kit.
[0052] This application provides a medical testing device, comprising: a mounting bracket having a first mounting position for detachably mounting a reagent kit; the reagent kit having a second mounting position for detachably mounting a testing component; wherein the testing component and the reagent kit can be docked or detached, such that the testing component and the reagent kit are connected or disconnected, and when connected, the reagents in the reagent kit can reach the testing component; and when the reagent kit is detached, the testing component can be detached synchronously with the reagent kit.
[0053] The medical testing device provided in this application detachably mounts the detection component onto the reagent kit. When the first and second interfaces are connected, the reagent in the liquid package within the reagent kit can reach the first liquid path of the detection component for detection to obtain a detection signal. Furthermore, the processing circuit is detachably connected to the detection element of the detection component to receive the detection signal when the detection element is connected. In addition, when the processing circuit and detection element are disassembled, the detection component can be disassembled simultaneously with the reagent kit, avoiding the need to disassemble the detection component and the reagent kit separately, thus improving the ease of disassembly.
[0054] This application provides a biological tissue detection device, comprising: a support having a accommodating space and a first mounting position, the first mounting position being used to mount a sample measuring device, the accommodating space being used to move a reagent kit into or out, the reagent kit being used to deliver liquid to the sample measuring device to assist the sample measuring device in performing sample measurement, the sample measuring device being used to measure the liquid flowing into the sample measuring device; wherein, the dimension of the accommodating space in the direction of reagent kit movement is larger than a predetermined movement dimension of the reagent kit, the support having a limiting portion and an elastic element, the limiting portion being used to position the reagent kit, and the elastic element being used to provide an elastic force when the reagent kit is moved into the accommodating space, so that the reagent kit retracts part of its travel after being moved into the accommodating space and abuts against the limiting portion.
[0055] This application provides a biological tissue detection device, comprising: a support having a accommodating space and a first mounting position; a sample measuring device detachably mounted on the first mounting position and having a first conduit; and a reagent kit capable of being moved into or out of the accommodating space and having a second conduit; wherein the accommodating space has a dimension larger than a predetermined dimension for the reagent kit in the direction of kit insertion, the support having a limiting portion and an elastic element, the limiting portion being used to position the reagent kit, and the elastic element being used to provide an elastic force when the reagent kit is inserted into the accommodating space, so that the reagent kit retracts part of its travel and abuts against the limiting portion after being inserted into the accommodating space.
[0056] The biological tissue detection device provided in this application uses a limiting part on the support to position the reagent kit when it is moved into the accommodating space of the support, and uses an elastic element on the support to provide an elastic force when the reagent kit is moved into the accommodating space. This elastic force allows the reagent kit to retract part of its travel after it is moved into the solute space to resist the limiting part, so as to achieve the positioning of the reagent kit in the accommodating space.
[0057] This application provides a sample analysis device, comprising: a base having a storage slot and a pick-and-place port communicating with the storage slot, the storage slot being used to move a detection card in or out, the detection card being moved in or out of the storage slot from the pick-and-place port; at least one of the storage slot and the detection card is provided with a locking member, the locking member being used to lock the detection card to the base when the detection card is moved into the storage slot; at least one of the base and the detection card is provided with an elastic member; wherein, when the detection card is moved into the storage slot, the detection card compresses or stretches the elastic member, causing the elastic member to deform and generate elastic force; when the locking member releases the locking of the detection card, the detection card pops out from the pick-and-place port under the action of the elastic force.
[0058] The sample analysis apparatus provided in this application embodiment facilitates the placement of test cards by providing a storage slot on the base for inserting or removing them. Furthermore, a locking member secures the test card to the base for subsequent testing. Additionally, an elastic member allows the test card to pop out when the locking member releases its grip, facilitating replacement.
[0059] This application provides a fluid detection instrument, comprising: a valve assembly having a control element, a first pipe, a first inlet, and a first outlet, wherein the control element controls the first inlet to be connected to one end of the first pipe, and the other end of the first pipe to be connected to the first outlet; and a reagent kit having a cavity, a second pipe, and a first interface, wherein the cavity is used to hold a reagent pack and a recovery pack, the first interface is used to connect the reagent pack and the first inlet, the first outlet is connected to a docking slot provided on the reagent kit, the docking slot is used to dock with a sampling element, one end of the second pipe is used to connect to the docking slot, and the other end is connected to the recovery pack; wherein the valve assembly and the reagent kit can be docked or separated, such that the first inlet and the first interface are connected or separated, and when connected, the first pipe can be connected to the docking slot under the control of the control element, so that the liquid in the reagent pack can reach the docking slot, and the liquid in the docking slot can reach the recovery pack via the second pipe.
[0060] This application provides a valve assembly, including: a control element, a first pipe, a first inlet, and a first outlet; wherein, the control element is used to control the first inlet to be connected to one end of the first pipe, and the other end of the first pipe to be connected to the first outlet; the first inlet is used to dock or disconnect with a first interface of a reagent kit, so that when docking, the control element controls the first inlet to obtain fluid from the reagent kit; and the first outlet is used to be connected to a docking slot of the reagent kit, so that when docking, the liquid in the reagent kit can reach the docking slot through the first outlet, and the liquid in the docking slot can reach the recycling package of the reagent kit through a second pipe of the reagent kit.
[0061] This application provides a reagent kit, comprising: a cavity, a second conduit, a first interface, and a docking groove; wherein, the cavity is used to hold a reagent pack and a recovery pack, one end of the second conduit is used to connect to the recovery pack, and the other end is used to connect to the docking groove; the first interface is used to connect or disconnect with a first inlet of a valve assembly, and the docking groove is used to connect to a first outlet of the valve assembly, so that during connection, liquid in the reagent pack can be transported to the delivery valve assembly through the first interface, and liquid in the docking groove can reach the recovery pack via the second conduit.
[0062] The fluid detection instrument provided in this application embodiment allows for docking or detachment of the reagent kit via a valve assembly, facilitating reagent kit replacement. Furthermore, when the valve assembly is docked with the reagent kit, a control element connects the first conduit to the docking slot, enabling liquid within the reagent kit to reach the docking slot. Simultaneously, the second conduit of the reagent kit connects to a recovery pack within the kit, allowing liquid from the docking slot to reach the recovery pack. This forms a liquid conduit, ensuring that liquid from the reagent kit reaches the recovery pack after reaching the docking slot. The liquid reaching the docking slot can be used to clean the sampling end of the sampling element on the reagent kit, maintaining the cleanliness of the sampling end and thus extending the lifespan of the reagent kit.
[0063] This application provides a liquid bag having a body and a connector. The body is used to contain liquid, and the connector is configured to control the liquid in the liquid bag to flow out of the connector or to seal the body. The connector has a pipe communicating with the internal space of the body and a seal disposed in the pipe. The seal is movable within the pipe under the action of an external force to open the pipe and returns to its initial position to seal the pipe when the external force is removed.
[0064] The liquid bag provided in this application embodiment has a pipe that connects to the internal space of the liquid bag body and a sealing element is provided in the pipe. This allows the sealing element to move inside the pipe to open or seal the pipe, eliminating the need to set a structure on the liquid bag to open or seal the pipe, thus improving the convenience of using the liquid bag.
[0065] This application provides an integrated reagent kit, comprising: a housing and a sampling assembly disposed on the housing; wherein, the sampling assembly includes a rotating component rotatably connected to the housing and a sampling component connected to the rotating component; the rotating component is capable of changing its state under the action of a first external force to drive the sampling component to rotate synchronously relative to the housing, and is capable of returning to its state when the first external force is removed; the sampling component includes a sampling needle and a sleeve sleeved on the sampling needle, the sleeve is capable of changing its state under the action of a second external force to move relative to the rotating component to expose the sampling needle, and is capable of returning to its state to cover the sampling needle when the second external force is removed.
[0066] The integrated reagent kit provided in this application provides a sampling component and a rotating component mounted on a housing. Under a first external force, the rotating component can rotate the sampling component relative to the housing to adjust its sampling angle, and the sampling component returns to its original state when the first external force is removed. Furthermore, a cannula fitted onto the sampling needle can move relative to the rotating component under a second external force to expose the sampling needle, allowing it to sample from the liquid container. When the second external force is removed, the cannula can cover the sampling needle. In other words, by providing a sampling component and a rotating component with the above-described structure on the housing, the sampling state of the sampling needle can be flexibly adjusted.
[0067] This application provides a reagent kit that is easy to clean, comprising: a box body, a first tube, a second tube, and a docking slot; the box body contains a reagent pack and a recovery pack, one end of the first tube is connected to the docking slot and the other end is connected to the reagent pack, one end of the second tube is connected to the docking slot and the other end is connected to the recovery pack; wherein, the docking slot is used to dock or detach with a sampling element, during docking, the liquid in the reagent pack can reach the docking slot through the first tube and clean the sampling end of the sampling element, and the cleaned liquid can reach the recovery pack through the second tube.
[0068] The reagent kit provided in this application embodiment connects the first pipe and the second pipe to the docking tank respectively, so that the liquid in the reagent kit can reach the docking tank and clean the sampling end of the sampling element. The cleaned liquid can reach the recovery bag, so that the sampling end of the sampling element of the reagent kit can be kept clean during use.
[0069] This application provides a sample analysis device, including: a reagent kit having a sampling component, an adjustment component, and a moving component. The adjustment component is used to drive the sampling component to rotate relative to the reagent kit; the moving component is configured to correspond to the sampling component; the moving component and the sampling component are capable of docking or separating; wherein, the moving component is capable of moving relative to the sampling component between a first position and a second position, wherein in the first position the moving component is docked with the sampling component, and in the second position the moving component is separated from the sampling component; the first position corresponds to limiting the sampling component so that the sampling component can collect liquid inside the reagent kit, and the second position corresponds to releasing the limitation on the sampling component so that the adjustment component can drive the sampling component to rotate, thereby enabling the sampling component to collect liquid outside the reagent kit.
[0070] The sample analysis device provided in this application embodiment allows the moving component to move between a first position and a second position relative to the sampling component, thereby achieving different sampling states of the sampling component. Specifically, in the first position, the sampling component is limited to collect liquid inside the reagent kit; in the second position, the limitation on the sampling component is released, allowing the adjusting component to rotate the sampling component, thus enabling the sampling component to collect liquid outside the reagent kit. In other words, the moving component and the adjusting component work together to allow the sampling component to switch between different sampling states, meeting the need for variable sampling positions in the sample analysis device.
[0071] This application provides a biological sample analysis device, comprising: a drive assembly having an output shaft; a reagent storage device having a storage cavity, a first connecting pipe, a second connecting pipe, and a squeezing assembly, wherein the storage cavity is used to place a reagent pack, a cleaning pack, and a recovery pack; the first connecting pipe and the second connecting pipe are both partially embedded in the squeezing assembly; one end of the first connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recovery pack; one end of the second connecting pipe is used to connect to the cleaning pack, and the other end is used to connect to the recovery pack; wherein the drive assembly and the reagent storage device can be docked or separated, so that the output shaft docks or separates from the squeezing assembly; when docked, the output shaft can drive the squeezing assembly to synchronously squeeze the first connecting pipe and the second connecting pipe so that the liquid in the first connecting pipe or the second connecting pipe can flow.
[0072] This application provides a reagent storage device, including: a storage cavity, a first connecting pipe, a second connecting pipe, and a squeezing assembly; wherein, the storage cavity is used to place a reagent pack, a cleaning pack, and a recycling pack, and the first connecting pipe and the second connecting pipe are both partially embedded in the squeezing assembly; one end of the first connecting pipe is used to connect to the reagent pack and the other end is used to connect to the recycling pack; one end of the second connecting pipe is used to connect to the cleaning pack and the other end is used to connect to the recycling pack; the squeezing assembly is used to dock with or disengage from the output shaft of a drive assembly, so that when docking, the output shaft drives the squeezing assembly to synchronously squeeze the first connecting pipe and the second connecting pipe so that the liquid in the first connecting pipe or the second connecting pipe can flow.
[0073] The biological sample analysis device provided in this application embeds a first connecting pipe and a second connecting pipe into a squeezing assembly. This allows the squeezing assembly to simultaneously squeeze the first and second connecting pipes, enabling liquid flow within either the first or second connecting pipe. This saves the space required for a separate squeezing assembly for each connecting pipe in the reagent storage device. Furthermore, the drive assembly can be docked with or detached from the reagent storage device. Specifically, the output shaft of the drive assembly can dock with or detach from the squeezing assembly. When docked, the drive assembly can drive the squeezing assembly to perform the aforementioned operation. Conversely, the reagent storage device can be detached from the drive assembly for easy replacement of the reagent storage device.
[0074] This invention provides a bioparameter analysis device, comprising: a housing having a window and a door capable of covering the window; a reagent kit capable of being moved into or out of the housing, the reagent kit having a sampling component and a docking component, wherein when the reagent kit is located inside the housing, the sampling component can be rotated out from the window to collect liquid outside the housing; the docking component can dock with the sampling component to enable the sampling component to collect liquid inside the reagent kit; and a linkage component that links the door and the docking component to drive the door to cover the window when the sampling component and the docking component are docked, and to drive the door to open the window when the sampling component and the docking component are separated.
[0075] The bioparameter analysis device provided in this application embodiment, by setting a linkage component between the door on the linkage housing and the docking component on the reagent kit, enables the door to close the window when the sampling component on the reagent kit docks with the docking component to collect the liquid inside the reagent kit, and drives the door to open the window when the sampling component and the docking component separate. At this time, the sampling component can rotate out from the window to collect the liquid outside the reagent kit. By setting the above-mentioned linkage component to link the movement relationship between the docking component and the door, the separate drive mechanism for opening and closing the door can be eliminated, which helps to simplify the overall structure of the device.
[0076] This application provides a sample parameter analysis device, comprising: a housing having a window and a door capable of covering the window; the housing having a first side and a second side disposed opposite to each other, the door being disposed on the first side and rotatably connected to the housing; a connecting assembly disposed on the second side of the housing to connect the housing and the door when the door covers the window; the connecting assembly including a locking member, a driving member, and a first elastic member, one end of the first elastic member being connected to the middle of the locking member and the other end being connected to the housing, one end of the locking member being connected to the driving member and the other end being used to restrict the position of the door when the door covers the window; wherein, the driving member is used to drive the locking member to move to release the restriction on the door, so that the door can rotate relative to the housing and thus open the window, and the first elastic member deforms to generate elastic force when the locking member moves, the elastic force acting on the locking member when the driving member retracts its drive to the locking member, thereby causing the locking member to return to its original position.
[0077] The sample parameter analysis device provided in this application embodiment uses a connecting component to fix the door when it blocks the window, and the connecting component can also release the restriction on the door to allow the door to move and open the window. Specifically, a locking member is used to restrict and fix the door when it closes the window, and a driving member is used to drive the locking member to move and release the restriction on the door. Simultaneously, a first elastic member connects the locking member and the housing, so that when the locking member releases the restriction on the door, it deforms to generate elastic force. This elastic force allows the locking member to return to its original position without requiring the driving member to re-drive it back to its original position, resulting in a simple overall structure.
[0078] This application provides a sample analysis kit, comprising: a base having a first cavity, a second cavity, and an isolator, wherein the isolator is configured to connect or isolate the first cavity and the second cavity, wherein when the first cavity and the second cavity are connected, liquid in the first cavity can flow to the second cavity; wherein the isolator can change its state under the action of an external force to make the first cavity and the second cavity connect, and when the external force is removed, the isolator returns to its state to isolate the first cavity and the second cavity.
[0079] The sample analysis kit provided in this application embodiment isolates the first and second cavities within the housing. When the kit is not in use, the isolation element is changed by external force to connect the first and second cavities, allowing liquid in the first cavity to flow into the second cavity for analysis. Furthermore, when the kit is not in use at the factory, the isolation between the first and second cavities ensures that salt bridges exposed in the second cavity remain dry, thus extending the kit's shelf life.
[0080] This application provides a detection component, including: a first liquid path, a second liquid path, an inlet, an outlet, and a valve assembly; one end of the first liquid path is connected to the inlet, and the other end is connected to the outlet; one end of the second liquid path is connected to the inlet, and the other end is connected to the outlet; the valve assembly is located between the inlet, the outlet, and / or the inlet and the outlet, and can switch between a first conducting state and a second conducting state to control the first liquid path and the second liquid path to be selectively conducting; wherein, in the first conducting state, a first external liquid of the detection component can flow into the first liquid path from the inlet and flow out of the first liquid path from the outlet; in the second conducting state, a second external liquid of the detection component can flow into the second liquid path from the inlet and flow out of the second liquid path from the outlet.
[0081] The detection component provided in this application embodiment controls the selective conduction of a first liquid path and a second liquid path via a valve assembly. When the second liquid path is open, a second external liquid, such as a reference liquid, can enter the second liquid path. When the first liquid path is open, a first external liquid, such as a test sample, can enter the first liquid path. This eliminates the need to pre-fill the detection component with auxiliary measurement liquids such as reference liquids when it is assembled. Instead, the valve assembly controls the conduction of the second liquid path and injects the auxiliary measurement liquids such as reference liquids into it during use. This reduces the volume of the assembled detection component and avoids the problem of the auxiliary measurement liquids such as reference liquids expiring due to the detection component being placed inside and the component not being used for a long time. Attached Figure Description
[0082] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0083] Figure 1 This is a schematic diagram of the structure of a blood gas analysis device in one embodiment of this application;
[0084] Figure 2 This is a schematic diagram of the structure of the detection component in one embodiment of this application;
[0085] Figure 3 This is a schematic diagram of the structure of the reagent kit in one embodiment of this application;
[0086] Figure 4 This is a schematic diagram of the mounting bracket of the blood gas analysis device in one embodiment of this application;
[0087] Figure 5 This is a structurally exploded schematic diagram of the liquid sample detection device in some embodiments of this application;
[0088] Figure 6 yes Figure 5 Schematic diagram of the structural breakdown of the adjustment device in the embodiment;
[0089] Figure 7 This is a structural breakdown diagram of the biological tissue detection device in some embodiments of this application;
[0090] Figure 8 yes Figure 7 A schematic diagram showing the structural breakdown of the biological tissue detection framework in the embodiment;
[0091] Figure 9 This is a structural breakdown diagram of the sample analysis device in some embodiments of this application;
[0092] Figure 10 yes Figure 9 A schematic diagram showing the structural breakdown of the conveying component in the embodiment;
[0093] Figure 11 yes Figure 9 A schematic diagram of the structural breakdown of the test component in the embodiment;
[0094] Figure 12 yes Figure 11 A schematic diagram showing the structural breakdown of the supporting component in the embodiment;
[0095] Figure 13 This is a structurally disassembled schematic diagram of the biological detection device in some embodiments of this application;
[0096] Figure 14 yes Figure 13 A partial structural schematic diagram of the biological detection device in the embodiment;
[0097] Figure 15 yes Figure 13 A partial structural schematic diagram of the biological detection device in the embodiment;
[0098] Figure 16 This is a structural breakdown diagram of the blood sample analysis platform in some embodiments of this application;
[0099] Figure 17 yes Figure 16 A partial structural diagram of the blood sample analysis platform in the embodiment;
[0100] Figure 18 yes Figure 16 A partial structural diagram of the blood sample analysis platform in the embodiment;
[0101] Figure 19 This is a structurally exploded schematic diagram of the fluid detection instrument in some embodiments of this application;
[0102] Figure 20 yes Figure 19 A partial structural schematic diagram of the fluid detection instrument in the embodiment;
[0103] Figure 21 yes Figure 19 A partial structural schematic diagram of the fluid detection instrument in the embodiment;
[0104] Figure 22 These are schematic diagrams of the integrated reagent kit in some embodiments of this application;
[0105] Figure 23 This is a partial structural schematic diagram of the reagent storage device in some embodiments of this application;
[0106] Figure 24 yes Figure 23 A schematic diagram of the cross-sectional structure of the reagent storage device in the embodiment;
[0107] Figure 25 This is a structural breakdown diagram of the liquid parameter measurement platform in some embodiments of this application;
[0108] Figure 26 yes Figure 25 A partial structural schematic diagram of the liquid parameter measurement platform in the embodiment;
[0109] Figure 27 yes Figure 25 A partial structural breakdown diagram of the liquid parameter measurement platform in the embodiment;
[0110] Figure 28 This is a structural breakdown diagram of the biological sample analysis device in some embodiments of this application;
[0111] Figure 29 yes Figure 28 A partial structural schematic diagram of the biological sample analysis device in the embodiment;
[0112] Figure 30 yes Figure 28 A partial structural breakdown diagram of the biological sample analysis device in the embodiment;
[0113] Figure 31 This is a structurally exploded schematic diagram of the liquid drive device in some embodiments of this application;
[0114] Figure 32 yes Figure 31 A partial structural schematic diagram of the liquid drive device in the embodiment;
[0115] Figure 33 This is a partial structural breakdown diagram of the sample analysis device in some embodiments of this application;
[0116] Figure 34 This is a schematic diagram of the liquid circuit structure of the medical testing device in some embodiments of this application;
[0117] Figure 35 These are schematic diagrams of the structure of the medical testing equipment in some embodiments of this application;
[0118] Figure 36 yes Figure 35 A structural breakdown diagram of the medical testing equipment in the embodiment;
[0119] Figure 37 This is a schematic diagram of the liquid circuit structure of the medical testing device in some embodiments of this application;
[0120] Figure 38 These are schematic diagrams of the structure of the medical testing equipment in some embodiments of this application;
[0121] Figure 39 yes Figure 38 A structural breakdown diagram of the medical testing equipment in the embodiment;
[0122] Figure 40 These are schematic diagrams of the biological tissue detection device in some embodiments of this application;
[0123] Figure 41 yes Figure 40 Another schematic diagram of the biological tissue detection device in the embodiment;
[0124] Figure 42 yes Figure 40 A schematic diagram of the liquid circuit structure of the biological tissue detection device in the embodiment;
[0125] Figure 43 This is a schematic diagram of the sample analysis device in some embodiments of this application;
[0126] Figure 44 yes Figure 43 A partial structural breakdown diagram of the sample analysis device in the embodiment;
[0127] Figure 45 yes Figure 43 A schematic diagram showing the structural breakdown of another part of the sample analysis device in the embodiment;
[0128] Figure 46 This is a structurally exploded schematic diagram of the fluid detection instrument in some embodiments of this application;
[0129] Figure 47 yes Figure 46 A schematic diagram of the cross-sectional structure of the valve assembly of the fluid detection instrument in the embodiment;
[0130] Figure 48 yes Figure 46 A schematic diagram of the fluid circuit structure of the fluid detection instrument in the embodiment;
[0131] Figure 49 These are schematic diagrams of the liquid bag structure in some embodiments of this application;
[0132] Figure 50 These are schematic diagrams of the integrated reagent kit in some embodiments of this application;
[0133] Figure 51 yes Figure 50 Another structural schematic diagram of the integrated reagent kit in the embodiment;
[0134] Figure 52 yes Figure 50 Another structural schematic diagram of the integrated reagent kit in the embodiment;
[0135] Figure 53 These are schematic diagrams of the reagent kit structure in some embodiments of this application;
[0136] Figure 54 yes Figure 53 A partial cross-sectional structural diagram of the reagent kit in the embodiment;
[0137] Figure 55 These are schematic diagrams of the sample analysis equipment in some embodiments of this application;
[0138] Figure 56 yes Figure 55 A schematic diagram showing the structural breakdown of the sample analysis equipment in the embodiment;
[0139] Figure 57 yes Figure 55 A partial structural breakdown diagram of the sample analysis device in the embodiment;
[0140] Figure 58 These are schematic diagrams of the biological sample analysis device in some embodiments of this application;
[0141] Figure 59 yes Figure 58A schematic diagram showing the structural breakdown of the biological sample analysis device in the embodiment;
[0142] Figure 60 yes Figure 58 A partial structural breakdown diagram of the biological sample analysis device in the embodiment;
[0143] Figure 61 These are schematic diagrams of the bioparameter analysis device in some embodiments of this application;
[0144] Figure 62 yes Figure 61 A structural breakdown diagram of the bioparameter analysis device in the embodiment;
[0145] Figure 63 yes Figure 61 A partial structural schematic diagram of the bioparameter analysis device in the embodiment;
[0146] Figure 64 This is a schematic diagram of the sample parameter analysis device in some embodiments of this application;
[0147] Figure 65 yes Figure 64 A schematic diagram showing the structural breakdown of the sample parameter analysis device in the embodiment;
[0148] Figure 66 yes Figure 64 A partial structural breakdown diagram of the sample parameter analysis device in the embodiment;
[0149] Figure 67 This is a schematic diagram of the sample analysis box structure in some embodiments of this application;
[0150] Figure 68 yes Figure 67 A schematic diagram showing the structural breakdown of the sample analysis box in the embodiment;
[0151] Figure 69 yes Figure 67 A schematic diagram of the cross-sectional structure of the sample analysis box in the embodiment;
[0152] Figure 70 This is a structural breakdown diagram of the detection component in some embodiments of this application;
[0153] Figure 71 yes Figure 70 A partial structural breakdown diagram of the detection component in the embodiment;
[0154] Figure 72 yes Figure 70 A schematic diagram of the liquid circuit structure of the detection component in the embodiment. Detailed Implementation
[0155] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.
[0156] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a mutually exclusive, independent, or alternative embodiment. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.
[0157] One embodiment of this application provides a blood gas analysis device, including:
[0158] The first detection component has a detection element, a first liquid path and a first interface, the first liquid path and the first interface are connected, and the detection element is used to perform blood gas detection on the liquid in the first liquid path;
[0159] The reagent kit has a cavity, a second liquid passage, and a second interface. The cavity is used to hold a liquid pack, one end of the second liquid passage is used to connect to the liquid pack, and the other end is used to connect to the second interface.
[0160] The first detection component and the reagent kit can be docked or separated, so that the first interface and the second interface are connected or separated. When connected, the first liquid path is connected to the second liquid path so that the reagent in the liquid package can reach the first liquid path. When the reagent kit is moved into the mounting bracket of the blood gas analyzer, the first interface and the second interface are connected.
[0161] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0162] The reagent kit has a first connecting tube, one end of which is used to connect to the liquid bag, and the other end of which is used to connect to the sampling end of the sampling element; wherein, the first connecting tube constitutes another part of the second liquid path.
[0163] The first detection component has a third interface spaced apart from the first interface, and the third interface is connected to the first liquid path; the reagent kit has a fourth interface and a second connecting tube, and the fourth interface and the second interface are spaced apart; one end of the second connecting tube is connected to the fourth interface and the other end is connected to the cavity; wherein, when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0164] The cavity wall has a docking seat on its outer side, the second interface and the fourth interface are located on the docking seat, and the second connecting pipe is located between the cavity wall and the docking seat.
[0165] The liquid package includes a reagent package and a recovery package placed in the cavity. One end of the first connecting tube is used to connect to the reagent package, and one end of the second connecting tube is used to connect to the recovery package.
[0166] The reagent kit is provided with a liquid line exposed in the cavity. The liquid line constitutes another part of the second liquid line. The liquid flowing out of the first liquid line flows through the liquid line and reaches the cavity.
[0167] The blood gas analyzer further includes a second detection component mounted on the mounting bracket. The second detection component is used to detect the liquid in the liquid pipeline exposed outside the cavity. The first detection component is used to perform blood gas detection, and the second detection component is used to perform blood oxygen detection.
[0168] Another aspect of this application provides a detection component, including:
[0169] The housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element;
[0170] The first liquid path and the first interface are connected. The detection element is used to perform blood gas detection on the liquid in the first liquid path. The first interface is used to dock with or disconnect from the second interface of the reagent kit so that the reagent of the reagent kit can be obtained through the first interface when docking. When docking, the connection terminal is used to electrically connect with the processing circuit of the blood gas analysis device.
[0171] The housing is provided with a positioning element for positioning with the bracket on the blood gas analyzer where the detection components are installed.
[0172] The end of the first interface that mates with the second interface has a tapered recess or a tapered protrusion to guide the second interface to mate with the first interface.
[0173] Another aspect of this application provides a reagent kit, comprising:
[0174] The cavity, the second liquid passage, and the second interface;
[0175] The cavity is used to hold a liquid package. One end of the second liquid path is connected to the liquid package, and the other end is connected to the second interface. The second interface is used to dock with or disconnect from the first interface of the first detection component, so that when docking, the reagent in the liquid package is delivered to the first detection component through the second interface. The reagent kit can be moved into or out of the mounting bracket of the blood gas analysis device. When the reagent kit is moved into, the first interface and the second interface are connected.
[0176] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0177] The reagent kit is provided with a liquid line exposed in the cavity. The liquid line constitutes another part of the second liquid line. The liquid flowing out from the first detection component flows through the liquid line and reaches the cavity.
[0178] The blood gas analyzer further includes a second detection component mounted on the mounting bracket. The second detection component is used to detect the liquid in the liquid pipeline exposed outside the cavity. The first detection component is used to perform blood gas detection, and the second detection component is used to perform blood oxygen detection.
[0179] The first detection component has a third interface spaced apart from the first interface; the reagent kit has a fourth interface spaced apart from the second interface; wherein, when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0180] The cavity wall has a docking seat on its outer side, and the second interface and the fourth interface are located on the docking seat.
[0181] Another embodiment of this application provides a blood gas analysis device, including:
[0182] The mounting bracket has a first mounting position and a second mounting position. The first mounting position is used for detachably mounting a first detection component, and the second mounting position is used for placing a reagent kit.
[0183] The first detection component and the reagent kit can be docked or separated, so that the first detection component and the reagent kit are connected or separated. When connected, the reagents in the reagent kit can reach the first detection component.
[0184] The mounting bracket further includes a third mounting position for detachably mounting a second detection component. The reagent kit has a liquid conduit exposed to the cavity from the third mounting position. Liquid flowing from the first detection component passes through the liquid conduit and reaches the cavity. The second detection component is used to detect the liquid in the liquid conduit exposed outside the cavity. The first detection component is used for blood gas detection, and the second detection component is used for blood oxygen detection.
[0185] The mounting bracket includes a fixed bracket and a movable bracket. The fixed bracket has a cavity that forms the second mounting position, and the movable bracket has a receiving cavity that forms the first mounting position. When the reagent kit is moved into the cavity, the movable bracket can move relative to the fixed bracket so that the first detection component can dock with the reagent kit.
[0186] The movable support can move relative to the fixed support along a first direction or a second direction;
[0187] When the movable bracket moves relative to the fixed bracket in a first direction, the first detection component can move into or out of the movable bracket;
[0188] As the movable support moves relative to the fixed support in the second direction, the first detection component can dock with or detach from the reagent kit.
[0189] Another aspect of this application provides an adjustment device that can be used in a liquid sample detection device, including:
[0190] First adjustment component and second adjustment component;
[0191] The first adjustment component is used to adjust the rotation angle of the sampling element relative to the liquid sample detection device, so as to switch between a first fluid path and a second fluid path for conveying liquid;
[0192] The second adjustment component is used to adjust the axial position of the sleeve fitted on the sampling element so that the sleeve can switch between a first position and a second position.
[0193] When the sleeve is in the first position, the sampling element can enable the connection of the first fluid path;
[0194] When the sleeve is in the second position, the first adjustment component can adjust the rotation angle of the sampling element to achieve the connection of the second fluid path.
[0195] The first adjustment assembly includes an adjustment seat for mounting on the liquid sample detection device, a first power component disposed on the adjustment seat, and an adjustment bracket. The first power component can drive the adjustment bracket to rotate. The adjustment bracket is used to assemble with the sampling element to adjust the rotation angle of the sampling element relative to the liquid sample detection device.
[0196] The first adjustment component further includes a rotating member disposed between the adjustment seat and the adjustment bracket. The rotating member is connected to the adjustment bracket, and the first power component can drive the rotating member to rotate, thereby driving the adjustment bracket to rotate.
[0197] The adjusting seat is provided with a rotating groove, and the rotating component is at least partially housed in the rotating groove and can rotate relative to the rotating groove;
[0198] The rotating groove is provided with a shaft hole, and the adjusting bracket is provided with a rotating shaft. The rotating shaft passes through the rotating component and is inserted into the shaft hole.
[0199] The first power component is located on the side of the adjusting seat opposite to the rotating component, and the rotating shaft of the first power component passes through the adjusting seat and is connected to the rotating component in a transmission manner.
[0200] The bottom wall of the rotating groove is provided with an arc-shaped groove extending along the rotation direction of the rotating component. A first positioning component is provided on the arc-shaped groove, and a slider that can slide along the arc-shaped groove is provided on the rotating component. The slider cooperates with the first positioning component to obtain the rotation angle of the rotating component relative to the adjusting seat.
[0201] The adjusting bracket is assembled with the second adjusting component so that when the first power component drives the adjusting bracket to rotate, the second adjusting component can rotate synchronously with the adjusting bracket.
[0202] The second adjustment component includes a second power component mounted on the adjustment bracket and a movable bracket connected to the second power component. The second power component can drive the movable bracket to move relative to the adjustment bracket. When the liquid sample detection device is docked with the reagent kit, the sampling element is nested on one side of the movable bracket. The movable bracket is connected to the sleeve of the sampling element and can drive the sleeve to switch between a first position and a second position.
[0203] The movable support includes a first movable support and a second movable support. The first movable support is connected to the second power component, and the second movable support is elastically connected to the first movable support. When the liquid sample detection device is docked with the reagent kit, the second movable support is connected to the sleeve.
[0204] Another aspect of this application provides a liquid sample detection device, including:
[0205] The main body has a first mounting position;
[0206] An adjustment device is installed at the first mounting position;
[0207] The adjusting device includes:
[0208] A first adjustment component and a second adjustment component; the first adjustment component is used to adjust the rotation angle of the sampling element relative to the body to switch between a first fluid path and a second fluid path for conveying liquid; the second adjustment component is used to adjust the axial position of the sleeve sleeved on the sampling element to switch the sleeve between a first position and a second position.
[0209] When the sleeve is in the first position, the sampling element can connect the first fluid path; when the sleeve is in the second position, the first adjustment component can adjust the rotation angle of the sampling element to connect the second fluid path.
[0210] The first adjustment assembly includes an adjustment seat mounted on the main body, a first power component disposed on the adjustment seat, and an adjustment bracket. The first power component can drive the adjustment bracket to rotate. The adjustment bracket is used to assemble with the sampling element to adjust the rotation angle of the sampling element relative to the liquid sample detection device.
[0211] The second adjustment component includes a second power component mounted on the adjustment bracket and a movable bracket connected to the second power component. The second power component can drive the movable bracket to move relative to the adjustment bracket. When the main body is docked with the reagent kit, the sampling element is nested on one side of the movable bracket. The movable bracket is connected to the sleeve and can drive the sleeve to switch between a first position and a second position.
[0212] Another aspect of this application provides a biological tissue detection framework, including:
[0213] A plurality of plates are connected to each other to form a cavity and a first mounting position, the first mounting position being used to install a biological tissue measurement platform, and the cavity being used to contain auxiliary consumables.
[0214] The cavity and the first mounting position have a clearance channel, which is used to avoid mechanical docking operations and consumable delivery paths between the biological tissue measurement platform and the auxiliary consumables. The consumable delivery path is a passage connecting the first pipe of the biological tissue measurement platform and the second pipe of the auxiliary consumables.
[0215] The plurality of plates include a top plate and a bottom plate arranged opposite to each other, the cavity is formed between the top plate and the bottom plate, the clearance channel passes through the top plate, and the first mounting position is located on the side of the top plate away from the bottom plate.
[0216] The cavity has an opening for taking in and putting out the auxiliary consumables, which can be moved into or out of the cavity through the opening. A limiting member is provided on the side of the top plate away from the bottom plate, and the limiting member spans the clearance channel. The limiting member is used to limit the height of the auxiliary consumables protruding from the top plate through the clearance channel.
[0217] The plurality of plates further include a side plate disposed between the top plate and the bottom plate, the side plate being opposite to the pick-and-place port; the side plate having a first pair of interfaces and a second mounting position, the first pair of interfaces communicating with the cavity, and the second mounting position for mounting an adjustment device; wherein, when the auxiliary consumable is moved into the cavity, the sampling element on the auxiliary consumable is exposed through the first pair of interfaces to dock with the adjustment device.
[0218] The side plate has a second pair of interfaces and a third mounting position. The second pair of interfaces communicates with the cavity, and the third mounting position is used to install a valve device. When the auxiliary consumable is moved into the cavity, the liquid bag connector of the auxiliary consumable is exposed through the second pair of interfaces to dock with the valve device.
[0219] The side plate has a third pair of interfaces and a fourth mounting position. The third pair of interfaces communicates with the cavity, and the fourth mounting position is used to install a driving device. When the auxiliary consumable is moved into the cavity, the driving device extends into the cavity from the third pair of interfaces and docks with the auxiliary consumable to drive the liquid flow in the auxiliary consumable.
[0220] The clearance passage passes through the first mounting position, and the first mounting position is provided with a positioning component, which is used to position the biological tissue measurement platform on the top plate.
[0221] Another embodiment of this application provides a biological tissue detection device, including:
[0222] A biological tissue framework having a cavity and a first mounting site;
[0223] A biological tissue measurement platform, detachably mounted at the first mounting position, has a first conduit;
[0224] Auxiliary consumables, capable of being moved into or out of the cavity, have a second conduit;
[0225] The cavity and the first mounting position have a clearance channel, which is used to avoid mechanical docking operations and consumable delivery paths between the biological tissue measurement platform and the auxiliary consumables. The consumable delivery path is a passage connecting the first pipe and the second pipe.
[0226] The biological tissue framework includes several plates, each including a top plate and a bottom plate disposed opposite to each other, and a side plate disposed between the top plate and the bottom plate. The bottom plate, the top plate, and the side plate surround a cavity with an access port. The auxiliary consumable can be moved into or out of the cavity through the access port. The clearance channel passes through the top plate. The first mounting position is located on the side of the top plate away from the bottom plate.
[0227] The auxiliary consumable has a sampling element, and the biological tissue detection device has an adjustment device for adjusting the sampling posture of the sampling element. The side plate has a first pair of interfaces and a second mounting position. The first pair of interfaces communicates with the cavity, and the second mounting position is used to install the adjustment device. When the auxiliary consumable is moved into the cavity, the sampling element docks with the adjustment device.
[0228] The auxiliary consumable has a receiving cavity for holding a liquid bag, the cavity wall of which is provided with a liquid bag connector. The biological tissue detection device has a valve device for docking with the liquid bag connector to control the liquid outflow from the liquid bag. The side plate has a second pair of interfaces and a third mounting position. The second pair of interfaces communicates with the cavity, and the third mounting position is used to install the valve device. When the auxiliary consumable is moved into the cavity, the liquid bag connector docks with the valve device.
[0229] The auxiliary consumable has a receiving cavity for holding a liquid bag, the cavity wall of which is provided with a first driving member. The biological tissue detection device has a driving device for docking with the first driving member to drive the liquid in the liquid bag to flow out. The side plate has a third pair of interfaces and a fourth mounting position. The third pair of interfaces communicates with the cavity, and the fourth mounting position is used to install the driving device. When the auxiliary consumable is moved into the cavity, the driving device docks with the first driving member.
[0230] Another embodiment of this application provides a sample analysis apparatus, including:
[0231] A fixed base and a mounting base are provided, and a guide rod is provided between the fixed base and the mounting base;
[0232] A conveying assembly is disposed between the fixed base and the mounting base, and the conveying assembly is sleeved on the guide rod, and the conveying assembly can slide along the guide rod;
[0233] A test component is disposed between the fixed base and the mounting base, and the test component is sleeved on the guide rod, and the test component can slide along the guide rod;
[0234] The test component is located on the side of the conveying component away from the fixed base. A first elastic element is provided between the conveying component and the fixed base so that the conveying component and the fixed base can be separated by the first elastic element. A second elastic element is provided between the conveying component and the test component so that the conveying component and the test component can be separated by the second elastic element.
[0235] The conveying assembly includes a support seat sleeved on the guide rod and slidable along the guide rod, a telescopic seat slidably connected to the support seat, and a first driving member disposed on the support seat. The first elastic member is disposed between the support seat and the fixed seat, and the first driving member can drive the telescopic seat to move relative to the support seat.
[0236] The support seat has a channel that passes through the support seat along the moving direction of the telescopic seat, and the telescopic seat is partially disposed in the channel and can move relative to the support seat along the channel.
[0237] The telescopic base is provided with a slot for placing the detection component. When the telescopic base moves relative to the support base, the slot can switch between a first position and a second position.
[0238] When the card slot is in the first position, the detection component can move into or out of the card slot;
[0239] When the card slot is in the second position, the card slot is received within the channel.
[0240] The support includes a top wall and a bottom wall disposed opposite to each other. The bottom wall is located on the side of the support near the fixed base, and the top wall is located on the side of the support near the test component. The channel is formed between the top wall and the bottom wall. The top wall has a first clearance hole, and the bottom wall has a second clearance hole. When the slot is in the second position, the detection element of the detection component placed in the slot is exposed to the first clearance hole, and the test component can dock with the detection element of the detection component through the first clearance hole. The liquid hole of the detection component is exposed to the second clearance hole.
[0241] The telescopic seat is equipped with a transmission component, which is assembled with the first driving component to drive the telescopic seat to move under the drive of the first driving component.
[0242] The telescopic seat is provided with a clearance groove, the transmission component is provided on the groove wall of the clearance groove, and the output shaft of the first drive component extends into the clearance groove and is connected to the transmission component for transmission.
[0243] The test assembly includes a test seat sleeved on the guide rod and slidable along the guide rod, and a test plate disposed on the test seat. The test plate is provided with a test head, wherein when the test seat and the support seat are connected, the test head contacts the detection element of the detection assembly through the first clearance hole.
[0244] The test assembly further includes a support assembly disposed on the test seat, and the second elastic element is disposed between the support assembly and the test seat; when the test seat and the support seat are docked so that the test head contacts the detection element of the detection assembly, the second elastic element is compressed to generate an elastic force, which enables the support assembly and the support seat to separate.
[0245] The test base has a first mounting position and a second mounting position on the same side. The test plate is mounted at the first mounting position, and the top-holding assembly is mounted at the second mounting position. Before the second elastic member is compressed, the height of the top-holding assembly protruding from the test base is not less than the height of the test head protruding from the test base.
[0246] The supporting assembly includes a body and a limiting member. The limiting member is fixed to the second mounting position, and the second elastic member is disposed between the body and the second mounting position. The body and the limiting member are slidably connected, and the limiting member is used to limit the sliding stroke of the body under the action of the elastic force.
[0247] The mounting base is provided with a second driving component, which is used to drive the test base to slide along the guide rod.
[0248] Another embodiment of this application provides a biological detection device, including:
[0249] First base and second base;
[0250] A guide member is located between the first base and the second base, and extends in the arrangement direction of the first base and the second base;
[0251] A test component is disposed on the guide and is movable along the guide;
[0252] A transmission assembly is mounted on the first base, and the transmission assembly includes a driving component;
[0253] The test component has a top support on the side near the first base, and the drive component rolls with the top support to drive the test component to move along the guide.
[0254] The transmission assembly includes a power component mounted on the first base and a support shaft passing through the drive component. The power component and the support shaft are connected in a transmission assembly to drive the support shaft to rotate, and the rotation of the support shaft causes the drive component to rotate synchronously.
[0255] The biological detection device further includes an assembly bracket and a drive bracket spaced apart on the first base, a support shaft located between the assembly bracket and the drive bracket, and a power component mounted on the drive bracket.
[0256] The first base is provided with a clearance hole for avoiding the drive component; the assembly bracket is provided on the side of the first base near the test component; at least one of the first base and the test component is provided with an isolation member, which is provided between the first base and the test component to prevent the assembly bracket from interfering with the rolling engagement between the drive component and the top support.
[0257] The assembly bracket includes a first bracket and a second bracket spaced apart, the second bracket being disposed between the first bracket and the drive bracket, and the support shaft being disposed between the first bracket and the drive bracket; wherein the drive component is disposed between the first bracket and the second bracket and is disposed corresponding to the clearance hole, and the power component and the support shaft are connected in a transmission assembly between the second bracket and the drive bracket.
[0258] The first bracket is provided with a first positioning element, and the driving element or the support shaft is provided with a second positioning element. The second positioning element rotates synchronously with the driving element or the support shaft and cooperates with the first positioning element to obtain the rotation angle of the driving element or the support shaft.
[0259] The power component is located on the side of the drive bracket away from the second bracket, and the output shaft of the power component passes through the drive bracket and is connected to the support shaft for transmission.
[0260] The transmission assembly includes a first transmission assembly disposed between the drive bracket and the second bracket. The output shaft of the power component passes through the drive bracket and extends into the space between the drive bracket and the second bracket, and is provided with a first transmission wheel at its end. The support shaft is provided with a second transmission wheel at its portion located between the drive bracket and the second bracket. The first transmission assembly is respectively connected to the first transmission wheel and the second transmission wheel for transmission.
[0261] The first transmission assembly includes a first fixed shaft disposed between the drive bracket and the second bracket, a first driving wheel and a first driven wheel disposed on the first fixed shaft; the first driving wheel is drivenly assembled with the first transmission wheel, and the first driven wheel is drivenly assembled with the second transmission wheel;
[0262] Wherein, the diameter of the first driving wheel is greater than the diameter of the first driven wheel, the axial thickness of the first driving wheel is less than the axial thickness of the first transmission wheel, the diameter of the first driven wheel is less than the diameter of the second transmission wheel, and the axial thickness of the second transmission wheel is less than the axial thickness of the first driven wheel.
[0263] The transmission assembly includes a second transmission assembly disposed between the first transmission assembly and the second transmission wheel, the second transmission assembly being respectively connected to the first transmission assembly and the second transmission wheel.
[0264] The second transmission assembly includes a second fixed shaft disposed between the drive bracket and the second bracket, a second driving wheel and a second driven wheel disposed on the second fixed shaft; the second driving wheel is drivenly assembled with the first driven wheel, and the second driven wheel is drivenly assembled with the second transmission wheel;
[0265] Wherein, the diameter of the second driving wheel is larger than the diameter of the second driven wheel, the axial thickness of the second driving wheel is smaller than the axial thickness of the first driven wheel, the diameter of the second driven wheel is smaller than the diameter of the second transmission wheel, and the axial thickness of the second transmission wheel is smaller than the axial thickness of the second driven wheel.
[0266] The first bracket and the test component are provided with a limiting block and a limiting groove, respectively. The limiting block and the limiting groove cooperate to limit the distance between the first base and the test component.
[0267] The driving component is a turbine, and the top support component is a roller.
[0268] Another embodiment of this application provides a blood sample analysis platform, including:
[0269] The blood sample analyzer features non-contact detection elements and clearance grooves;
[0270] An auxiliary liquid container has a cavity and a liquid passage. The cavity is used to hold the auxiliary liquid and a waste liquid pack. One end of the liquid passage is used to input the auxiliary liquid, and the other end is used to connect to the waste liquid pack.
[0271] The liquid path has a portion exposed outside the auxiliary liquid box, and the non-contact detection element is used to detect the portion entering the clearance groove.
[0272] The blood sample analysis platform includes a mounting bracket with a receiving cavity and a first mounting position. The auxiliary liquid box can be moved into or out of the receiving cavity. The first mounting position is used to install the blood sample analyzer. The receiving cavity and the first mounting position are provided with a clearance channel. When the auxiliary liquid box is moved into the receiving cavity, a portion of it enters the clearance groove through the clearance channel.
[0273] The auxiliary liquid box is provided with a sample inlet seat, and the liquid path includes a liquid channel disposed within the sample inlet seat; wherein, when the auxiliary liquid box moves into the receiving cavity, the sample inlet seat moves into the clearance groove, so that the non-contact detection element can detect the liquid in the liquid channel.
[0274] The liquid channel includes an inlet section, an outlet section, and a detection section connecting the inlet section and the outlet section. The inlet section is used to input the auxiliary liquid, and the outlet section is used to connect to the waste liquid bag. When the sample seat moves into the clearance groove, the non-contact detection element can detect the liquid in the detection section.
[0275] The sample inlet is provided with a light-transmitting area corresponding to the detection section, so that the light emitted by the blood sample analyzer can shine through the light-transmitting area onto the liquid in the detection section for detection.
[0276] The blood sample analyzer includes a test base and a test plate. The test base is installed at the first mounting position, and the test plate is installed on the test base. The clearance groove is formed on the test base. The non-contact detection element includes a light source and a photosensitive device disposed on the test plate. The light emitted by the light source can pass through the light-transmitting area to reach the photosensitive device and thus detect the liquid in the detection section.
[0277] The blood sample analyzer includes an ultrasonic transmitter, which is mounted on the test base to perform ultrasonic treatment on the liquid in the liquid channel entering the clearance tank.
[0278] Another embodiment of this application provides a blood sample analyzer, including:
[0279] A test holder and a non-contact detection element are provided, wherein the test holder is provided with a clearance groove; the non-contact detection element is connected to the test holder and is used to detect liquid entering the clearance groove.
[0280] The test seat is used to dock with or detach from the auxiliary liquid box, and the liquid path of the auxiliary liquid box has a curved portion that protrudes from the auxiliary liquid box; when the test seat and the auxiliary liquid box dock, the portion enters the clearance groove to be detected by the non-contact detection element.
[0281] The blood sample analyzer includes a test base and a test plate. The test base is installed at the first mounting position, and the test plate is installed on the test base. The clearance groove is formed on the test base. The non-contact detection element includes a light source and a photosensitive device disposed on the test plate. The light emitted by the light source can pass through the portion to reach the photosensitive device and thus detect the liquid in the portion.
[0282] The blood sample analyzer includes an ultrasonic transmitter, which is mounted on the test base for ultrasonic treatment of the liquid entering the portion of the clearance tank.
[0283] Another embodiment of this application provides an auxiliary liquid cartridge, including:
[0284] Cavity and fluid passage;
[0285] The cavity is used to hold the auxiliary liquid and the waste liquid pack. One end of the liquid path is used to input the auxiliary liquid, and the other end is used to connect to the waste liquid pack. The liquid path has a portion exposed outside the auxiliary liquid box. When the auxiliary liquid box is docked with the blood sample analyzer, the portion enters the clearance groove of the blood pressure analyzer so that it can be detected by the non-contact detection element of the blood sample analyzer.
[0286] The auxiliary liquid box is provided with a sample inlet seat, and the liquid path includes a liquid channel disposed within the sample inlet seat. When the auxiliary liquid box is docked with the blood sample analyzer, the sample inlet seat moves into the clearance groove so that the non-contact detection element can detect the liquid in the liquid channel.
[0287] The liquid channel includes an inlet section, an outlet section, and a detection section connecting the inlet section and the outlet section. The inlet section is used to input the auxiliary liquid, and the outlet section is used to connect to the waste liquid bag. When the sample seat moves into the clearance groove, the non-contact detection element can detect the liquid in the detection section.
[0288] The sample inlet is provided with a light-transmitting area corresponding to the detection section, so that the light emitted by the blood sample analyzer can shine through the light-transmitting area onto the liquid in the detection section for detection.
[0289] Another embodiment of this application provides a fluid detection instrument, including:
[0290] A valve assembly has a control element, a first pipe, an inlet, and an outlet. The number of inlets is several. The control element is used to control one of the inlets to be connected to one end of the first pipe, and the other end of the first pipe to be connected to the outlet.
[0291] A fluid cartridge has a cavity and an interface. The cavity is used to hold a fluid pack, and one end of the interface is used to connect to the fluid pack, while the other end is used to connect to the inlet.
[0292] The valve assembly and the fluid box can be docked or separated, so that the inlet and the interface can be docked or separated. When connected, the first pipe can be connected to the interface under the control of the control element, so that the fluid in the fluid box can reach the first pipe.
[0293] The valve assembly has an air vent, and one end of the first pipe is selectively connected to the inlet or the air vent under the control of the control element.
[0294] The fluid box is provided with a docking groove for docking with a sampling element. The docking groove is provided with a through hole and a connecting pipe passing through the through hole. One end of the connecting pipe is connected to the outlet, and the other end is connected to the sampling end of the sampling element. The connecting pipe is in sealed contact with the wall of the through hole.
[0295] The sampling element includes a sampling needle, a sleeve fitted on the sampling needle, and a docking member at the end of the sleeve. The outer diameter of the sleeve does not exceed the inner diameter of the docking groove, and the docking member has a through hole. The docking member can move along the axial direction of the sampling needle with the sleeve so that the sampling needle is inserted into one end of the through hole or passes through the through hole and is exposed on one side of the docking member.
[0296] Wherein, when the sleeve moves along the axial direction of the sampling needle and toward the connecting tube so that the docking member is inserted into the docking groove, the sampling needle and the connecting tube are respectively inserted at both ends of the through hole to achieve communication.
[0297] Another embodiment of this application provides a valve assembly, including:
[0298] Control components, first pipe, inlet, and outlet;
[0299] The number of inlets is several, and the control element is used to control one of the several inlets to connect to one end of the first pipe, and the other end of the first pipe to connect to the outlet; the inlet is used to dock or disconnect with the interface of the fluid box, so that when docking, the control element controls the inlet to obtain the fluid of the fluid box.
[0300] The valve assembly has an air vent, and one end of the first pipe is selectively connected to the inlet or the air vent under the control of the control element.
[0301] Another embodiment of this application provides a fluid cartridge, including:
[0302] Cavity and interface;
[0303] The cavity is used to hold a fluid pack, one end of the interface is used to connect to the fluid pack, and the other end is used to connect to the inlet of the valve assembly; the valve assembly and the fluid pack can be docked or separated, so that when docked, the fluid in the fluid pack can be transported to the valve assembly through the interface.
[0304] The fluid box is provided with a docking groove for docking with a sampling element. The docking groove is provided with a through hole and a connecting pipe passing through the through hole. One end of the connecting pipe is connected to the outlet of the valve assembly, and the other end is connected to the sampling end of the sampling element. The connecting pipe is in sealed contact with the wall of the through hole.
[0305] The sampling element includes a sampling needle, a sleeve fitted on the sampling needle, and a docking member at the end of the sleeve. The outer diameter of the sleeve does not exceed the inner diameter of the docking groove, and the docking member has a through hole. The docking member can move along the axial direction of the sampling needle with the sleeve so that the sampling needle is inserted into one end of the through hole or passes through the through hole and is exposed on one side of the docking member.
[0306] Wherein, when the sleeve moves along the axial direction of the sampling needle and toward the connecting tube so that the docking member is inserted into the docking groove, the sampling needle and the connecting tube are respectively inserted at both ends of the through hole to achieve communication.
[0307] Another aspect of this application provides an integrated reagent kit, comprising:
[0308] The box has a receiving space for storing reagent packs and recycling packs;
[0309] A sampling device is disposed on the box body and located outside the containment space;
[0310] The first and second pipes are located on the housing.
[0311] The sampling device has an input end that is connected to the reagent pack via the first pipe, and an output end that is connected to the recovery pack via the second pipe. The sampling device is rotatable relative to the box body so that the input end of the sampling device can collect liquid from the reagent pack or an external container.
[0312] The box body has a first interface and a second interface spaced apart. The first interface is connected to the output end of the sampling device, and the second interface is connected to the recovery bag through the second pipe. The first interface and the second interface are used to interface with the detection component so that the liquid collected by the sampling device can reach the detection component.
[0313] The box body is provided with a sample inlet located outside the receiving space. The first interface and the second interface are provided on the sample inlet. The sample inlet is provided with a first connecting tube and a second connecting tube. One end of the first connecting tube is connected to the first interface and the other end is connected to the output end of the sampling device. One end of the second connecting tube is connected to the second interface and the other end is used to connect to the recovery pack.
[0314] The output end of the sampling device is inserted into the sample inlet and connected to the first connecting tube.
[0315] The sample inlet includes a base and a tube at the end of the base. The first interface and the second interface are located on the base. One end of the first connecting tube is inserted into the tube and the other end is connected to the first interface. The output end of the sampling device is inserted into the tube to communicate with the first connecting tube.
[0316] The sampling device includes a sampling element, a sleeve fitted onto the input end of the sampling element, and a buckle fitted onto the output end of the sampling element. The buckle is rotatably assembled with the sleeve so that the buckle can rotate relative to the sleeve. The rotation of the buckle can drive the sleeve to rotate so that the input end of the sampling element can collect liquid from the reagent pack or external container.
[0317] The tube body has a first hole section and a second hole section that are connected to each other. The first hole section is used to rotately connect with the buckle. The output end of the sampling element and the first connecting tube are connected through the second hole section. The diameter of the first hole section is larger than the diameter of the second hole section.
[0318] The rotating buckle includes a first rotating buckle and a second rotating buckle that are clamped to the sleeve. The first rotating buckle is rotatably assembled with the tube body, and the second rotating buckle can rotate relative to the tube body under the action of external force, thereby driving the sleeve to rotate.
[0319] The sleeve is axially movable along the sampling end of the sampling element under the action of external force, so as to expose or cover the sampling end of the sampling element; the sleeve is provided with a clearance hole to avoid the sampling element when the sleeve moves axially.
[0320] The box body is provided with a docking seat, which has an interface for docking with the input end of the sampling device. One end of the first pipe is connected to the connection port, and the other end is used to connect to the reagent pack.
[0321] Another aspect of this application provides a reagent storage device, including:
[0322] A storage box, a sampling component and a docking component disposed on the storage box and located outside the storage box;
[0323] The sampling component has an outlet end connected to a first position inside the storage box, and the docking component has a sampling slot connected to a second position inside the storage box. The sampling component and the docking component can be connected or separated. When the sampling component and the docking component are connected, the inlet end of the sampling component is inserted into the sampling slot to take a sample from the second position inside the storage box. When the sampling component and the docking component are separated, the inlet end can take a sample from outside the storage box.
[0324] The docking assembly includes a docking seat mounted on the storage box, a sampling slot formed on the docking seat, and a connector tube provided in the sampling slot. One end of the connector tube is used to connect to the inlet end of the sampling assembly, and the other end is used to connect to the second position. The inlet end of the sampling assembly is provided with a connector, and when the sampling assembly and the docking assembly are connected, the connector tube is inserted into the connector.
[0325] The sampling assembly includes a sampling element that can be inserted into or pass through the connector; when the sampling assembly and the docking assembly are connected, the sampling end of the sampling element is inserted into the connector, and the connector tube is inserted into the connector to communicate with the sampling end of the sampling element.
[0326] The docking assembly includes a seal embedded in the sampling groove, and the connector tube passes through the seal. When the connector tube is inserted into the connector, the seal abuts against the connector.
[0327] The end of the connector near the seal is tapered and recessed to guide the connector tube into the connector.
[0328] The docking seat is provided with a mating groove with an opening facing the storage box. One end of the connector tube extends into the mating groove to connect to a second position inside the storage box via a connecting tube, and the other end extends into the sampling groove to be inserted into the connector when the sampling component and the docking component are connected.
[0329] The sampling assembly includes a sleeve fitted onto the sampling element, a connector embedded at the end of the sleeve, and a locking member fitted onto the connector at the end of the sleeve, the locking member being connected to the sleeve; wherein the radial width of the locking member is greater than the radial width of the sealing element, and the radial width of the locking member does not exceed the radial width of the sampling groove.
[0330] The docking component includes a slider that is slidably connected to the docking seat. The slider can abut against the sampling component to stabilize the sampling state of the sampling component.
[0331] The docking seat is provided with a mating hole, and the sliding member passes through the mating hole and is elastically connected to the storage box, so that the sliding member can slide relative to the docking seat.
[0332] The mating hole includes a first mating section and a second mating section that are connected to each other. The cross-sectional area of the first mating section is smaller than that of the second mating section. The first mating section is located between the second mating section and the storage box. The sliding member includes a sliding part and a stopping part. The sliding part can slide relative to the first mating section, and the stopping part can slide relative to the second mating section and stop at the second mating section.
[0333] The docking assembly includes an elastic element disposed between the storage box and the sliding element; wherein one end of the elastic element is connected to the sliding element and the other end is connected to the storage box.
[0334] The docking seat is provided with a clearance groove that penetrates the side wall of the sampling slot. The inlet end of the sampling component can be rotated out of the sampling slot through the clearance groove, so that the inlet end can take samples from outside the storage box.
[0335] Another embodiment of this application provides a liquid parameter measurement platform, including:
[0336] A liquid loading box has a liquid dispensing component and an adjusting component; wherein the adjusting component is configured to be driven by an external force to rotate the liquid dispensing component relative to the liquid loading box by an angle.
[0337] A rotating component and a moving component; wherein, the rotating component rotates synchronously with the moving component, and the moving component is movable relative to the rotating component;
[0338] The adjusting component and the rotating component can be docked or separated. When the adjusting component and the rotating component are docked, the rotating component can drive the adjusting component to rotate relative to the liquid loading box, thereby driving the liquid taking component to rotate relative to the liquid loading box.
[0339] The liquid-collecting component and the moving component can follow the docking or disengagement of the adjusting component and the rotating component to achieve the corresponding docking or disengagement.
[0340] When the liquid-collecting component and the moving component are docked, the moving component is used to adjust the axial position of at least a portion of the liquid-collecting component so that the rotating component can drive the liquid-collecting component to switch between a first posture and a second posture.
[0341] The first posture corresponds to limiting the liquid collection component to collect liquid inside the liquid loading box, and the second posture corresponds to limiting the liquid collection component to collect liquid outside the liquid loading box.
[0342] The liquid collection assembly includes a liquid collection element and a sleeve. The liquid collection end of the liquid collection element is used to collect the internal or external liquid of the liquid loading box. The liquid collected by the liquid collection element flows through the liquid outlet end of the liquid collection element to the interior of the liquid loading box or the liquid recovery container.
[0343] The sleeve is fitted onto the liquid-collecting end of the liquid-collecting element and can dock with the moving component to adjust the axial position of the sleeve relative to the liquid-collecting element under the drive of the moving component.
[0344] The adjusting component includes a rotating buckle that clamps the sleeve. One end of the rotating buckle is sleeved on the liquid outlet end of the liquid-collecting element, and the other end can be connected to or separated from the rotating component. When the rotating component and the rotating buckle are connected, the rotating component can drive the rotating buckle to rotate, thereby driving the sleeve and the liquid-collecting element to rotate.
[0345] The rotating assembly includes an adjustment seat for mounting on the liquid parameter measuring platform, a first power component disposed on the adjustment seat, and an adjustment bracket. The first power component can drive the adjustment bracket to rotate. The adjustment bracket is used to assemble with the rotating buckle to adjust the rotation angle of the rotating buckle relative to the liquid loading box.
[0346] The rotating assembly further includes a rotating component disposed between the adjusting seat and the adjusting bracket. The rotating component is connected to the adjusting bracket to achieve synchronous rotation, and the first power component can drive the rotating component to rotate.
[0347] The first power component is located on the side of the adjusting seat opposite to the rotating component, and the output shaft of the first power component passes through the adjusting seat and is connected to the rotating component in a transmission manner.
[0348] The adjusting seat is provided with a rotating groove, and the rotating component is at least partially embedded in the rotating groove. The output shaft of the first power component is connected to the rotating component to drive the rotating component to rotate relative to the rotating groove.
[0349] The rotating groove is provided with a shaft hole, and the adjusting bracket is provided with a rotating shaft. The rotating shaft passes through the rotating component and is inserted into the shaft hole.
[0350] The bottom wall of the rotating groove is provided with an arc-shaped groove extending along the rotation direction of the rotating component. A first positioning component is provided on the arc-shaped groove, and a slider that can slide along the arc-shaped groove is provided on the rotating component. The slider cooperates with the first positioning component to obtain the rotation angle of the rotating component relative to the adjusting seat.
[0351] The adjusting bracket is assembled with the moving component so that when the first power component drives the adjusting bracket to rotate, the moving component can rotate synchronously with the adjusting bracket; wherein the adjusting bracket has an adjusting groove, and the moving component is embedded in the adjusting groove to achieve synchronous rotation with the adjusting bracket.
[0352] The movable component includes a second power component mounted on the adjusting bracket and a movable bracket connected to the second power component. The second power component can drive the movable bracket to move relative to the adjusting bracket.
[0353] When the adjusting component is docked with the rotating component, the sleeve of the liquid taking component is nested on one side of the movable support, and the movable support is connected to the sleeve and can drive the sleeve to switch between a first position and a second position.
[0354] The movable component further includes a fixed bracket embedded in the adjustment groove, and one end of the output shaft of the second power component passes through the fixed bracket to connect with the movable bracket.
[0355] An elastic element is provided between the fixed bracket and the movable bracket. The movable bracket moves relative to the fixed bracket under the drive of the second power element, causing the elastic element to generate elastic force. When the drive is removed, the elastic force causes the movable bracket to return to its original position.
[0356] The movable support has a first engaging portion, and the sleeve has a second engaging portion. When the adjusting component and the rotating component are connected, the first engaging portion and the second engaging portion engage and connect.
[0357] Another embodiment of this application provides a liquid loading box, which can be used in a liquid parameter measurement platform, including:
[0358] A liquid dispensing assembly and an adjusting assembly, wherein the adjusting assembly is configured to be driven by an external force to cause the liquid dispensing assembly to rotate relative to the liquid loading box by an angle.
[0359] The adjusting component is used to dock with or separate from the rotating component. When the adjusting component and the rotating component are docked, the rotating component can drive the adjusting component to rotate relative to the liquid loading box, thereby driving the liquid taking component to rotate relative to the liquid loading box.
[0360] The liquid-collecting component is used to dock with or separate from the moving component. The liquid-collecting component and the moving component can dock or separate in accordance with the docking or separation of the adjusting component and the rotating component. When the liquid-collecting component and the moving component dock, the moving component can adjust at least part of the axial position of the liquid-collecting component so that the rotating component can drive the liquid-collecting component to switch between a first state and a second state.
[0361] The first posture corresponds to limiting the liquid collection component to collect liquid inside the liquid loading box, and the second posture corresponds to limiting the liquid collection component to collect liquid outside the liquid loading box.
[0362] The liquid collection assembly includes a liquid collection element and a sleeve. The liquid collection end of the liquid collection element is used to collect the internal or external liquid of the liquid loading box. The liquid collected by the liquid collection element flows through the liquid outlet end of the liquid collection element to the interior of the liquid loading box or the liquid recovery container.
[0363] The sleeve is fitted onto the liquid-collecting end of the liquid-collecting element and is used to dock with the moving component to adjust the axial position of the sleeve relative to the liquid-collecting element under the drive of the moving component.
[0364] The adjusting component includes a rotating buckle that clamps the sleeve. One end of the rotating buckle is sleeved on the liquid outlet end of the liquid-collecting element, and the other end is used to connect or disconnect with the rotating component. When the rotating component and the rotating buckle are connected, the rotating component can drive the rotating buckle to rotate, thereby driving the sleeve and the liquid-collecting element to rotate.
[0365] Another aspect of this application provides a motion device that can be used in a liquid parameter measurement platform, including:
[0366] A rotating component and a moving component, wherein the rotating component rotates synchronously with the moving component, and the moving component is movable relative to the rotating component;
[0367] The rotating component is used to dock with or detach from the adjustment component of the liquid loading box. When the rotating component and the adjustment component are docked, the rotating component can drive the adjustment component to rotate relative to the liquid loading box, thereby driving the liquid dispensing component of the liquid loading box to rotate relative to the liquid loading box.
[0368] The moving component is used to dock with or separate from the liquid-taking component; the moving component and the liquid-taking component can dock or separate in accordance with the docking or separation of the adjusting component and the rotating component; when the liquid-taking component and the moving component dock, the moving component is used to adjust at least part of the axial position of the liquid-taking component so that the rotating component can drive the liquid-taking component to switch between a first posture and a second posture.
[0369] The first posture corresponds to limiting the liquid collection component to collect liquid inside the liquid loading box, and the second posture corresponds to limiting the liquid collection component to collect liquid outside the liquid loading box.
[0370] The rotating assembly includes an adjustment seat for mounting on the liquid parameter measuring platform, a first power component disposed on the adjustment seat, and an adjustment bracket. The first power component can drive the adjustment bracket to rotate. The adjustment bracket is used to assemble with the adjustment assembly to adjust the rotation angle of the adjustment assembly relative to the liquid loading box.
[0371] The adjusting bracket is assembled with the moving component so that when the first power component drives the adjusting bracket to rotate, the moving component can rotate synchronously with the adjusting bracket; wherein the adjusting bracket has an adjusting groove, and the moving component is embedded in the adjusting groove to achieve synchronous rotation with the adjusting bracket.
[0372] The movable component includes a second power component mounted on the adjusting bracket and a movable bracket connected to the second power component. The second power component can drive the movable bracket to move relative to the adjusting bracket.
[0373] When the adjusting component is docked with the rotating component, the sleeve of the liquid taking component is nested on one side of the movable support, and the movable support is connected to the sleeve and can drive the sleeve to switch between a first position and a second position.
[0374] Another embodiment of this application provides a biological sample analysis device, including:
[0375] Drive component, with output shaft;
[0376] A reagent storage device includes a storage cavity, a connecting pipe, and a squeezing assembly. The storage cavity is used to hold reagent packs and recycling packs. The connecting pipe is partially embedded in the squeezing assembly. One end of the connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recycling pack.
[0377] The drive assembly and the reagent storage device can be docked or separated, so that the output shaft can be docked or separated from the extrusion assembly; when docked, the output shaft can drive the extrusion assembly to extrude the connecting pipe so that the liquid in the connecting pipe can flow.
[0378] The biological sample analysis device further includes a mounting bracket, which has a cavity and a first mounting position. The reagent storage device can be moved into or out of the cavity, and the drive component is installed at the first mounting position. The first mounting position is located at the end of the travel distance when the reagent storage device moves into the cavity.
[0379] The drive assembly is located outside the cavity, and there is a clearance hole between the cavity and the first mounting position. The output shaft of the drive assembly extends into the cavity through the clearance hole. When the reagent storage device is moved into the cavity, the output shaft of the drive assembly is driven and assembled with the extrusion assembly.
[0380] The extrusion assembly includes a first extruder and a second extruder. The second extruder is embedded in the first extruder and coaxially arranged with the first extruder. The connecting pipe portion is located between the first extruder and the second extruder. The second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the connecting pipe.
[0381] The first extruder is annular, and the second extruder has a rotating part and an extruding part. The rotating part is used to dock with the output shaft, and the extruding part is located on the periphery of the rotating part and can rotate synchronously with the rotating part.
[0382] The extrusion section is spaced apart from the first extrusion member, and the connecting pipe section is located between the extrusion section and the first extrusion member.
[0383] The rotating part has a shaft hole, one end of the output shaft is assembled with the shaft hole, and a bushing is fitted on the extrusion part for abutting the connecting pipe.
[0384] The cavity wall of the receiving chamber is provided with a receiving groove, the extrusion assembly is embedded in the receiving groove and coaxially arranged with the receiving groove, and the connecting pipe is located between the receiving groove and the extrusion assembly; wherein, the extrusion assembly is used for transmission assembly with the output shaft, so as to rotate relative to the receiving groove under the drive of the output shaft and thereby extrude the connecting pipe.
[0385] Another aspect of this application provides a reagent storage device, including:
[0386] Storage cavity, connecting pipes, and extrusion assembly;
[0387] The storage cavity is used to hold the reagent pack and the recycling pack, and the connecting pipe is embedded in the extrusion assembly; one end of the connecting pipe is used to connect the reagent pack and the other end is used to connect the recycling pack.
[0388] The extrusion assembly is used to dock with or disconnect from the output shaft of the drive assembly, so that when docking, the output shaft drives the extrusion assembly to extrude the connecting pipe so that the liquid in the connecting pipe can flow.
[0389] The extrusion assembly includes a first extruder and a second extruder. The second extruder is embedded in the first extruder and coaxially arranged with the first extruder. The connecting pipe portion is located between the first extruder and the second extruder. The second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the connecting pipe.
[0390] The first extruder is annular, and the second extruder has a rotating part and an extruding part. The rotating part is used to dock with the output shaft, and the extruding part is located on the periphery of the rotating part and can rotate synchronously with the rotating part.
[0391] The extrusion section is spaced apart from the first extrusion member, and the connecting pipe section is located between the extrusion section and the first extrusion member.
[0392] The rotating part has a shaft hole. One end of the output shaft is assembled with the shaft hole; a bushing is fitted on the extrusion part, and the bushing is used to abut against the connecting pipe.
[0393] The cavity wall of the receiving chamber is provided with a receiving groove, the extrusion assembly is embedded in the receiving groove and coaxially arranged with the receiving groove, and the connecting pipe is located between the receiving groove and the extrusion assembly; wherein, the extrusion assembly is used for transmission assembly with the output shaft, so as to rotate relative to the receiving groove under the drive of the output shaft and thereby extrude the connecting pipe.
[0394] Another aspect of this application provides a liquid-driven device, including:
[0395] Power components, rotating components, and fluid lines;
[0396] One of the power assembly and the rotating assembly has a rotating shaft, and the other has a mating part into which the rotating shaft can be inserted;
[0397] One of the rotating shaft and the mating part is provided with a snap-fit element, and the other is provided with a snap-fit groove;
[0398] The liquid tube is disposed inside the rotating assembly, and the rotation of the rotating assembly can squeeze the liquid tube.
[0399] The power component and the rotating component can be docked or separated, so that the rotating shaft can be inserted into or pulled out of the mating part; when the rotating shaft is inserted into the mating part, the rotating shaft can be rotated to make the buckle and the buckle groove engage and limit the position.
[0400] The fastener is located on the rotating shaft, and the fastening groove is located on the mating part. When the fastener is not subjected to external force, it protrudes from the circumference of the rotating shaft. When the rotating shaft is inserted into the mating part, the fastener is retracted into the rotating shaft due to the obstruction of the mating part. When the rotating shaft rotates relative to the mating part until the fastener is opposite to the fastening groove, the fastener protrudes from the circumference of the rotating shaft and engages with the fastening groove.
[0401] The fastener is located on the mating part, and the fastening groove is located on the rotating shaft. When the fastener is not subjected to external force, it protrudes from the mating part. When the rotating shaft is inserted into the mating part, the fastener is retracted into the mating part due to the obstruction of the rotating shaft. When the rotating shaft rotates relative to the mating part until the fastener is aligned with the fastening groove, the fastener protrudes from the mating part and engages with the fastening groove.
[0402] The end of the buckle that engages and limits with the buckle groove has a guide slope, which provides resistance when the rotating shaft is inserted into the mating part, so that the buckle retracts inward.
[0403] One end of the rotating shaft has a chamfer, which is used to guide the rotating shaft to be inserted into the mating part.
[0404] The rotating shaft or the mating part is provided with a mounting hole, the fastener is assembled in the mounting hole, and an elastic element is provided in the mounting hole to abut against the fastener. The elastic element generates elastic force when the fastener retracts, and when the fastener is opposite to the fastening groove, the elastic force causes the fastener to extend to engage with the fastening groove.
[0405] The mounting hole is provided with a first limiting part, and the buckle is provided with a second limiting part. The first limiting part and the second limiting part cooperate to limit the extension stroke of the buckle.
[0406] The rotating shaft is fitted with a first gear, and the power assembly includes a drive component and a second gear. The second gear is connected to the output shaft of the drive component for transmission. The first gear and the second gear are meshed, and the thickness of the first gear along the axial direction of the rotating shaft is less than the thickness of the second gear along the axial direction of the rotating shaft.
[0407] The first gear and the driving member are spaced apart along the axial direction of the rotating shaft.
[0408] The rotating assembly has a clamping space for holding the liquid tube and a window communicating with the clamping space, with both ends of the liquid tube extending out of the window from the clamping space.
[0409] Another aspect of this application provides a reagent kit, comprising:
[0410] Storage chamber, liquid tubing, and rotating assembly;
[0411] The receiving cavity is used to hold the reagent pack and the recycling pack. The liquid tube is located inside the rotating assembly. The rotation of the rotating assembly can squeeze the liquid tube so that the liquid in the reagent pack can reach the recycling pack through the liquid tube.
[0412] The rotating assembly is used to dock with or detach from the power assembly. One of the power assembly and the rotating assembly has a rotating shaft, and the other has a mating part into which the rotating shaft can be inserted. One of the rotating shaft and the mating part is provided with a snap-fit element, and the other is provided with a snap-fit groove.
[0413] When the rotating component is connected to the power component, the rotating shaft is inserted into the mating part, and the rotating shaft can be rotated to make the buckle and the buckle groove engage and limit the movement.
[0414] Another aspect of this application provides a sample analysis apparatus, including:
[0415] The mounting bracket has a first mounting position and a second mounting position, wherein the first mounting position is used to mount the reagent kit and the second mounting position is used to mount the power assembly;
[0416] The power component is used to dock with or detach from the rotating component of the reagent kit. One of the power component and the rotating component has a rotating shaft, and the other has a mating part into which the rotating shaft can be inserted. One of the rotating shaft and the mating part is provided with a snap-fit element, and the other is provided with a snap-fit groove.
[0417] When the rotating component is connected to the power component, the rotating shaft is inserted into the mating part, and the rotating shaft can be rotated to make the buckle and the buckle groove engage and limit the movement.
[0418] Another embodiment of this application provides a medical testing device, including:
[0419] The detection component has a detection element, a first liquid path, and a first interface, wherein the first liquid path and the first interface are connected, and the detection element is used to detect the liquid in the first liquid path to obtain a detection signal;
[0420] A processing circuit, detachably connected to the detection element of the detection assembly, is used to receive the detection signal when the detection element is connected;
[0421] The reagent kit has a cavity, a second liquid passage, and a second interface. The cavity is used to hold a liquid pack, and one end of the second liquid passage is connected to the liquid pack, while the other end is connected to the second interface.
[0422] The detection component and the reagent kit can be docked or detached, such that the first interface and the second interface are connected or disconnected. When connected, the first liquid path is connected to the second liquid path so that the reagent in the liquid package can reach the first liquid path. Furthermore, when the detection component and the reagent kit are separated to replace the reagent kit, the processing circuit remains electrically connected to the detection element of the detection component.
[0423] The medical testing device includes a mounting bracket with a first mounting position, a second mounting position, and a third mounting position. The first mounting position is used to mount the testing component, the second mounting position is used to place the reagent kit, and the processing circuit is located at the third mounting position.
[0424] The detection component and the processing circuit are capable of moving synchronously relative to the reagent kit while maintaining an electrical connection, so that the detection component can dock with or detach from the reagent kit; when the detection component and the reagent kit are detached, the reagent kit can be replaced.
[0425] The mounting bracket includes a fixed bracket, a first driving mechanism, a first movable bracket, and a second movable bracket. The first movable bracket is mounted on the fixed bracket, and the second movable bracket is connected to the first movable bracket. The first movable bracket is used to place the detection component, and the second movable bracket is used to assemble the processing circuit. The detection component and the processing circuit move relative to each other under the drive of the first driving mechanism, so that the detection element of the detection component is electrically connected to or disconnected from the processing circuit. Furthermore, the first driving mechanism drives the first movable bracket to move, so that the detection component can dock with or detach from the reagent kit.
[0426] The first movable bracket is provided with a storage slot for placing the detection component, and the detection component can be moved into or out of the storage slot. The second movable bracket is elastically connected to the first movable bracket. When the detection component is moved into the storage slot, the processing circuit can move toward the detection component and achieve electrical connection under the drive of the first driving mechanism.
[0427] The first movable bracket and the mounting bracket are elastically connected. Under the drive of the first driving mechanism, the detection component can move toward the reagent kit to generate elastic force and realize the connection between the first interface and the second interface; the detection component can also use the elastic force to move away from the reagent kit and realize the separation between the first interface and the second interface.
[0428] The mounting bracket includes a second driving mechanism and a liquid path selection component. The second driving mechanism is mounted on the second movable bracket and is used to drive the liquid path selection component to move. When the detection component and the reagent kit are docked, the liquid path selection component enables different liquid paths to flow through the detection component under the drive of the second driving mechanism.
[0429] The fixed support has a cavity for accommodating the reagent kit, the cavity wall of which is provided with a clearance opening, and the detection component is disposed outside the cavity; wherein, when the reagent kit is moved into the cavity, the second interface of the reagent kit is exposed from the clearance opening to achieve communication or separation with the first interface of the detection component.
[0430] The second interface of the reagent kit is located in a recessed area, the shape of which is adapted to the shape of the detection component.
[0431] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0432] The reagent kit has a first connecting tube, one end of which is used to connect to the liquid bag, and the other end of which is used to connect to the sampling end of the sampling element; wherein, the first connecting tube constitutes another part of the second liquid path.
[0433] The detection component has a third interface spaced apart from the first interface, and the third interface is connected to the first liquid path; the reagent kit has a fourth interface and a second connecting tube, and the fourth interface and the second interface are spaced apart; one end of the second connecting tube is connected to the fourth interface and the other end is connected to the cavity; when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0434] Another aspect of this application provides a detection component, including:
[0435] The housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element;
[0436] The first liquid path and the first interface are connected. The detection element is used to perform blood gas detection on the liquid in the first liquid path to obtain a detection signal. The first interface is used to dock with or disconnect from the second interface of the reagent kit so that the reagent of the reagent kit can be obtained through the first interface when docking. Furthermore, when the detection component and the reagent kit are disconnected to replace the reagent kit, the connection terminal remains electrically connected to the processing circuit of the medical testing device.
[0437] The housing is provided with a first positioning element for positioning with the bracket on the medical testing equipment on which the testing components are installed.
[0438] The end of the first interface that mates with the second interface has a tapered recess or a tapered protrusion to guide the second interface to mate with the first interface.
[0439] Another aspect of this application provides a reagent kit, comprising:
[0440] The cavity, the second liquid passage, and the second interface;
[0441] The cavity is used to hold a liquid pack. One end of the second liquid path is connected to the liquid pack, and the other end is connected to the second interface. The second interface is used to connect with the first interface of the detection component when the reagent kit is used for testing, so that the reagent in the liquid pack can be delivered to the detection component through the second interface during the connection. The second interface is separated from the detection component before the reagent kit is used for testing. The reagent kit can be moved into or out of the mounting bracket of the medical testing device. When the reagent kit is moved in, the first interface and the second interface are connected.
[0442] The second interface of the reagent kit is located in a recessed area, the shape of which is adapted to the shape of the detection component.
[0443] The recess is provided with a second positioning element for positioning with the detection component.
[0444] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0445] The detection component has a third interface spaced apart from the first interface; the reagent kit has a fourth interface spaced apart from the second interface; wherein, when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0446] Another embodiment of this application provides a medical testing device, including:
[0447] The mounting bracket has a first mounting position, a second mounting position, and a third mounting position, wherein the first mounting position is used to mount the detection component, and the second mounting position is used to mount the reagent kit.
[0448] The processing circuit is located at the third mounting position and is detachably connected to the detection component.
[0449] The detection component and the reagent kit can be docked or detached, allowing them to communicate or separate. When connected, the reagents in the reagent kit can reach the detection component. Furthermore, when the detection component and the reagent kit are detached to replace the reagent kit, the processing circuit remains electrically connected to the detection component.
[0450] The mounting bracket is provided with a processing circuit. The mounting bracket has a first mounting position, a second mounting position and a third mounting position. The first mounting position is used to install the detection component, the second mounting position is used to place the reagent kit, and the processing circuit is located at the third mounting position.
[0451] The detection component and the processing circuit are capable of moving synchronously relative to the reagent kit while maintaining an electrical connection, so that the detection component can dock with or detach from the reagent kit; when the detection component and the reagent kit are detached, the reagent kit can be replaced.
[0452] The mounting bracket includes a fixed bracket, a first driving mechanism, a first movable bracket, and a second movable bracket. The first movable bracket is mounted on the fixed bracket and connected to the second movable bracket. The first movable bracket is used to place the detection component, and the second movable bracket is used to assemble the processing circuit. The detection component and the processing circuit move relative to each other under the drive of the first driving mechanism, so that the detection element of the detection component is electrically connected to or disconnected from the processing circuit. Furthermore, the detection component drives the first movable bracket to move under the drive of the first driving mechanism, so that the detection component can dock with or detach from the reagent kit.
[0453] The first movable bracket is provided with a storage slot for placing the detection component, and the detection component can be moved into or out of the storage slot. The second movable bracket is elastically connected to the first movable bracket. When the detection component is moved into the storage slot, the processing circuit can move toward the detection component and achieve electrical connection under the drive of the first driving mechanism.
[0454] The first movable bracket and the mounting bracket are elastically connected. Under the drive of the first driving mechanism, the detection component can move toward the reagent kit to generate elastic force and realize the connection between the first interface and the second interface; the detection component can use the elastic force to move away from the reagent kit and realize the separation between the first interface and the second interface.
[0455] The mounting bracket includes a second driving mechanism and a liquid path selection component. The second driving mechanism is mounted on the second movable bracket and is used to drive the liquid path selection component to move. When the detection component and the reagent kit are docked, the liquid path selection component enables different liquid paths to flow through the detection component under the drive of the second driving mechanism.
[0456] Another embodiment of this application provides a medical testing device, including:
[0457] The detection component has a detection element, a first liquid path, and a first interface, wherein the first liquid path and the first interface are connected, and the detection element is used to detect the liquid in the first liquid path to obtain a detection signal;
[0458] The reagent kit has a cavity, a second liquid passage, and a second interface. The cavity is used to hold a liquid pack, and one end of the second liquid passage is connected to the liquid pack, while the other end is connected to the second interface.
[0459] The processing circuit is detachably connected to the detection element of the detection assembly and is used to receive the detection signal when the detection element is connected; when the processing circuit and the detection element are disassembled, the detection assembly can be disassembled synchronously with the kit.
[0460] The detection component is detachably mounted on the reagent kit so that the first interface and the second interface are connected or disconnected. When connected, the first liquid path is connected to the second liquid path so that the reagent in the liquid package can reach the first liquid path.
[0461] The medical testing device includes a mounting bracket with a first mounting position for placing the reagent kit; the reagent kit has a second mounting position for mounting the testing component.
[0462] The mounting bracket is provided with a clearance channel to avoid the second mounting position, so that the detection element of the detection assembly can be exposed from the clearance channel and thus be connected to the processing circuit.
[0463] The mounting bracket includes a fixed bracket, a movable bracket mounted on the fixed bracket, and a driving mechanism. The movable bracket is used to place the processing circuit. The detection component and the processing circuit move relative to each other under the drive of the driving mechanism, so that the detection element of the detection component can contact or disconnect from the processing circuit. When the detection element disconnects from the processing circuit, the detection component can be disassembled synchronously with the reagent kit.
[0464] The second interface of the reagent kit is located in a recessed area, the shape of which is adapted to the shape of the detection component.
[0465] The depth of the recess is not less than the thickness of the detection component.
[0466] The recess has an clearance notch on one side, which is used to remove the detection component placed on the recess.
[0467] The recess has a positioning groove formed around its periphery, which communicates with the recess and is used to guide the processing circuit to contact the detection element of the detection assembly.
[0468] The reagent kit has a first positioning part in the area where the second interface is located. The first positioning part is used to guide the detection component to be installed in the second mounting position, thereby guiding the first interface and the second interface to dock.
[0469] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0470] The reagent kit has a first connecting tube, one end of which is used to connect to the liquid bag, and the other end of which is used to connect to the sampling end of the sampling element; wherein, the first connecting tube constitutes another part of the second liquid path.
[0471] The detection component has a third interface spaced apart from the first interface, and the third interface is connected to the first liquid path; the reagent kit has a fourth interface and a second connecting tube, and the fourth interface and the second interface are spaced apart; one end of the second connecting tube is connected to the fourth interface and the other end is connected to the cavity; when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0472] Another aspect of this application provides a detection component, including:
[0473] The housing, a detection element and a first liquid path disposed within the housing, and a first interface and a connection terminal disposed on the housing, wherein the connection terminal is electrically connected to the detection element;
[0474] The first liquid path and the first interface are connected. The detection element is used to detect the liquid in the first liquid path to obtain a detection signal. The first interface is used to dock with or disconnect from the second interface of the reagent kit so that the reagent of the reagent kit can be obtained through the first interface when docking. The detection component is used to be installed on the reagent kit, and the connection terminal is used to be electrically connected to the processing circuit of the medical testing device.
[0475] The reagent kit has a first positioning part formed in the area where the second interface is located. , The housing is provided with a second positioning part, and the first positioning part and the second positioning part cooperate to guide the detection component to be installed on the reagent kit.
[0476] The reagent kit has a positioning groove in the area where the second interface is located, and the positioning groove is used to guide the processing circuit to contact the detection element of the detection component.
[0477] The end of the first interface that mates with the second interface has a tapered recess or a tapered protrusion to guide the second interface to mate with the first interface.
[0478] Another aspect of this application provides a reagent kit, comprising:
[0479] The cavity, the second liquid passage, and the second interface;
[0480] The cavity is used to hold the liquid pack. One end of the second liquid path is connected to the liquid pack, and the other end is connected to the second interface. The second interface is used to dock with the first interface of the detection component when the reagent kit is used for detection, so that the reagent in the liquid pack can be delivered to the detection component through the second interface during docking. Furthermore, the detection component is detachably installed on the reagent kit, and the detection component can be detached synchronously with the reagent kit when the reagent kit is disassembled.
[0481] The second interface of the reagent kit is located in a recessed area, the shape of which is adapted to the shape of the detection component.
[0482] The recess is provided with a first positioning part for positioning with the detection component.
[0483] The reagent kit is equipped with a sampling element. The sampling end of the sampling element is used to selectively collect the reagent in the liquid package or the external liquid of the reagent kit, and the sampling outlet end of the sampling element is used to connect to the second interface. When collecting the reagent in the liquid package, the sampling element constitutes part of the second liquid path.
[0484] The detection component has a third interface spaced apart from the first interface; the reagent kit has a fourth interface spaced apart from the second interface; wherein, when the first interface and the second interface are connected, the third interface and the fourth interface are connected.
[0485] Another embodiment of this application provides a medical testing device, including:
[0486] The mounting bracket has a first mounting position for removably mounting the reagent kit; the reagent kit has a second mounting position for removably mounting the detection component.
[0487] The detection component and the reagent kit can be docked or detached, so that the detection component and the reagent kit are connected or disconnected. When connected, the reagents in the reagent kit can reach the detection component. Furthermore, when the reagent kit is disassembled, the detection component can be disassembled synchronously with the reagent kit.
[0488] The medical testing equipment further includes a processing circuit, and the mounting bracket is provided with a clearance channel to avoid the second mounting position, so that the detection element of the detection component can be exposed from the clearance channel and thus achieve electrical connection with the processing circuit.
[0489] The mounting bracket includes a fixed bracket, a movable bracket mounted on the fixed bracket, and a driving mechanism. The movable bracket is used to place the processing circuit. The detection component and the processing circuit move relative to each other under the drive of the driving mechanism, so that the detection element of the detection component is electrically connected to or disconnected from the processing circuit. When the detection element is disconnected from the processing circuit, the detection component can be disassembled synchronously with the reagent kit.
[0490] Another embodiment of this application provides a biological tissue detection device, including:
[0491] A support has a accommodating space and a first mounting position for mounting a sample measuring device. The accommodating space is used for moving a reagent kit into or out of the kit. The reagent kit is used to deliver liquid to the sample measuring device to assist the sample measuring device in performing sample measurement. The sample measuring device is used to measure the liquid flowing into the sample measuring device.
[0492] The accommodating space is larger than the predetermined insertion size of the reagent kit in the direction of reagent kit insertion. The support is provided with a limiting part and an elastic element. The limiting part is used to position the reagent kit, and the elastic element is used to provide elastic force when the reagent kit is inserted into the accommodating space, so that the reagent kit retracts part of its travel and abuts against the limiting part after being inserted into the accommodating space.
[0493] The bracket has several plates that are connected to each other to form the accommodating space and the first mounting position.
[0494] The accommodating space and the first mounting position are provided with a clearance window, which is used to avoid mechanical docking operations and liquid delivery passages between the sample measuring device and the reagent kit. The liquid delivery passage is a passage connecting the first pipe of the sample measuring device and the second pipe of the reagent kit, and the first pipe and the second pipe are liquid delivery pipes.
[0495] The plurality of plates include a frame plate connected end to end and a mounting plate disposed on one side of the frame plate. The frame plate and the mounting plate cooperate to form the accommodating space. The first mounting position and the clearance window are disposed on the frame plate. The frame plate has a loading and unloading port on the side away from the mounting plate for the reagent kit to be moved in or out.
[0496] The frame plate is provided with at least one guide, which is used to guide the reagent kit into or out of the accommodating space.
[0497] The elastic element is disposed on the mounting plate or the frame plate. When the reagent kit is moved into the accommodating space, the elastic element is squeezed or stretched to generate elastic force. The direction of the elastic force is the direction in which the reagent kit moves out of the accommodating space.
[0498] The limiting part is disposed on the frame plate and is located adjacent to the pick-and-place port along the direction in which the reagent kit moves out of the accommodating space. The reagent kit is provided with a locking part corresponding to the limiting part. When the reagent kit retracts part of its travel after moving into the accommodating space, the locking part cooperates with the limiting part to position the reagent kit.
[0499] The mounting plate has a first pair of interfaces and a second mounting position. The first pair of interfaces communicates with the accommodating space, and the second mounting position is used to install an adjustment device. When the reagent kit is moved into the accommodating space, the sampling element on the reagent kit is exposed through the first pair of interfaces to dock with the adjustment device, so that the sampling element can obtain liquid inside or outside the reagent kit under the adjustment of the adjustment device and enter the second pipeline.
[0500] The mounting plate has a second pair of interfaces and a third mounting position. The second pair of interfaces communicates with the accommodating space, and the third mounting position is used to install a valve device. When the reagent kit is moved into the accommodating space, the liquid bag connector inside the reagent kit is exposed through the second pair of interfaces to mate with the valve device, so that the valve device can control the flow of liquid in the reagent kit into the second pipeline. When the sampling element mates with the reagent kit, the sampling element communicates with the liquid outlet of the valve device so that the sampling element can obtain liquid in the reagent kit and enter the second pipeline.
[0501] The mounting plate has a third pair of interfaces and a fourth mounting position. The third pair of interfaces connects to the accommodating space, and the fourth mounting position is used to install a driving device. When the reagent kit is moved into the accommodating space, the driving device connects to the reagent kit through the third pair of interfaces to drive the liquid flow in the second pipe.
[0502] The avoidance window extends through the first mounting position, and a positioning element is provided on the first mounting position. The positioning element is used to position the sample measuring device on the frame plate.
[0503] Another embodiment of this application provides a biological tissue detection device, including:
[0504] The bracket has a accommodating space and a first mounting position;
[0505] A sample measuring device, detachably mounted at the first mounting position, has a first conduit;
[0506] The reagent kit, capable of being moved into or out of the accommodating space, has a second conduit;
[0507] The accommodating space is larger than the predetermined insertion size of the reagent kit in the direction of reagent kit insertion. The support is provided with a limiting part and an elastic element. The limiting part is used to position the reagent kit, and the elastic element is used to provide elastic force when the reagent kit is inserted into the accommodating space, so that the reagent kit retracts part of its travel and abuts against the limiting part after being inserted into the accommodating space.
[0508] The accommodating space and the first mounting position are provided with a clearance window, which is used to avoid mechanical docking operations and liquid delivery passages between the sample measuring device and the reagent kit. The liquid delivery passage is a passage that connects the first pipe of the sample measuring device and the second pipe of the reagent kit.
[0509] The plurality of plates include a frame plate connected end to end and a mounting plate disposed on one side of the frame plate. The frame plate and the mounting plate cooperate to form the accommodating space. The first mounting position and the clearance window are disposed on the frame plate. The frame plate has a loading and unloading port on the side away from the mounting plate, which allows the reagent kit to be moved into or out of the accommodating space.
[0510] The kit includes a sampling element, and the biological component detection device includes an adjustment device for adjusting the sampling posture of the sampling element. The mounting plate has a first pair of interfaces and a second mounting position. The first pair of interfaces communicates with the accommodating space, and the second mounting position is used to mount the adjustment device. When the kit is moved into the accommodating space, the sampling element docks with the adjustment device so that the sampling element can acquire liquid inside or outside the kit and enter the second conduit under the adjustment of the adjustment device.
[0511] The reagent kit has a receiving cavity for containing a liquid bag, the cavity wall of which is provided with a liquid bag connector. The biological component detection device has a valve device for docking with the liquid bag connector to control the outflow of liquid from the liquid bag. The mounting plate has a second pair of interfaces and a third mounting position. The second pair of interfaces communicates with the receiving space, and the third mounting position is used to install the valve device. When the reagent kit is moved into the receiving space, the liquid bag connector docks with the valve device so that the valve device can control the liquid in the reagent kit to flow into the second pipe. When the sampling element docks with the reagent kit, the sampling element communicates with the liquid outlet of the valve device so that the sampling element can obtain the liquid in the reagent kit and enter the second pipe.
[0512] The reagent kit has a receiving cavity for containing a liquid bag, the cavity wall of which is provided with a first driving member. The biological tissue detection device has a driving device for docking with the first driving member to drive the liquid in the liquid bag to flow out. The mounting plate has a third pair of interfaces and a fourth mounting position. The third pair of interfaces communicates with the receiving space, and the fourth mounting position is used to install the driving device. When the reagent kit is moved into the receiving space, the driving device docks with the first driving member.
[0513] Another embodiment of this application provides a sample analysis apparatus, including:
[0514] A base has a storage slot and a take-out port communicating with the storage slot. The storage slot is used to move a detection card in or out, and the detection card moves in or out of the storage slot through the take-out port. At least one of the storage slot and the detection card is provided with a locking member, which is used to lock the detection card to the base when the detection card is moved into the storage slot. At least one of the base and the detection card is provided with an elastic member.
[0515] When the detection card is moved into the storage slot, the detection card squeezes or stretches the elastic element, causing the elastic element to deform and generate elastic force; when the locking member releases the locking and fixing of the detection card, the detection card pops out from the pick-up and drop-off port under the action of the elastic force.
[0516] The inner wall of the pick-and-place port is provided with a damping part, which is used to limit the ejection stroke of the detection card.
[0517] The base is provided with a driving component, which is used to drive the locking component to release the locking and fixing of the detection card.
[0518] The base has a receiving groove, and the receiving groove and the storage groove are spaced apart in the direction of movement of the detection card. The driving member is disposed in the receiving groove. One end of the locking member is assembled and connected to the driving member, and the other end is located in the storage groove to lock and fix the detection card in the storage groove.
[0519] The base has a clearance space connecting the storage slot and the receiving slot, and the locking member is at least partially disposed within the clearance space; wherein the locking member is rotatably connected to the base so as to rotate under the drive of the driving member and thereby release the locking and fixing of the detection card.
[0520] The elastic element is disposed in the receiving groove, and the seat is provided with a supporting member. One end of the supporting member is used to assemble and connect with the elastic element, and the other end is used to support the detection card. When the detection card is moved into the receiving groove, the detection card abuts against the supporting member so that the elastic element deforms and generates elastic force.
[0521] The receiving groove is provided with a stop portion, which is used to limit the movement stroke of the top holding member.
[0522] The elastic element is sleeved on the top holding member. When the detection card is moved into the receiving slot, the detection card abuts against the top holding member so that the elastic element abuts against the stop portion and generates elastic force.
[0523] The detection card has a first interface, a second interface, and a latching part on one side. The storage slot has a clearance opening. When the detection card is moved into the storage slot, the first interface and the second interface are exposed to the clearance opening for communication with the external liquid circuit. The latching part and the locking member lock and fix the card in place.
[0524] The storage slot is provided with at least one spring piece in the area adjacent to the pick-and-place port. The spring piece is used to position the detection card when the detection card is moved into the storage slot.
[0525] Another embodiment of this application provides a fluid detection instrument, including:
[0526] A valve assembly has a control element, a first pipe, a first inlet, and a first outlet. The control element is used to control the first inlet to be connected to one end of the first pipe, and the other end of the first pipe to be connected to the first outlet.
[0527] The reagent kit has a cavity, a second tube, and a first interface. The cavity is used to hold a reagent pack and a recovery pack. The first interface is used to connect the reagent pack and the first inlet. The first outlet is connected to a docking slot provided on the reagent kit. The docking slot is used to dock with a sampling element. One end of the second tube is connected to the docking slot, and the other end is connected to the recovery pack.
[0528] The valve assembly and the reagent kit can be docked or separated, so that the first inlet and the first interface are connected or separated. When connected, the first pipe can be connected to the docking groove under the control of the control element, so that the liquid in the reagent kit can reach the docking groove, and the liquid in the docking groove can reach the recovery pack via the second pipe.
[0529] The docking groove is provided with an inlet hole and an outlet hole. The inlet hole is used to communicate with the first outlet, and the outlet hole is used to communicate with the second pipe.
[0530] The docking groove is provided with an isolation section located between the liquid inlet and the liquid outlet, and a flow channel connecting the liquid inlet and the liquid outlet and bypassing the isolation section.
[0531] The sampling element includes a sampling needle, a sleeve fitted on the sampling needle, and a docking member at the end of the sleeve. The outer diameter of the sleeve does not exceed the inner diameter of the docking groove, and the docking member has a through hole. The docking member can move along the axial direction of the sampling needle with the sleeve so that the sampling needle is inserted into one end of the through hole or passes through the through hole and is exposed on one side of the docking member.
[0532] The valve assembly further includes a third pipe, a third inlet, and a third outlet. The control element is used to control the third inlet to be connected to one end of the third pipe, and the other end of the third pipe to be connected to the third outlet.
[0533] The reagent kit also has a fourth pipe and a second interface, the second interface being used to connect the third inlet and the reagent pack, the third outlet being used to connect to the sampling end of the sampling element, one end of the fourth pipe being used to connect to the sample outlet of the sampling element, and the other end being used to connect to the detection component of the fluid detection instrument.
[0534] The docking groove is provided with a through hole and a connecting pipe passing through the through hole. One end of the connecting pipe is connected to the third outlet, and the other end is used to connect to the sampling end of the sampling element. The connecting pipe is in sealed contact with the hole wall of the through hole. The sleeve moves along the axial direction of the sampling needle and toward the connecting pipe so that when the docking part is inserted into the docking groove, the sampling needle and the connecting pipe are respectively inserted at both ends of the through hole to achieve communication.
[0535] The valve assembly has a first vent and a second vent, and one end of the first pipe is selectively connected to the first inlet or the first vent under the control of the control element; one end of the third pipe is selectively connected to the third inlet or the second vent under the control of the control element.
[0536] Another embodiment of this application provides a valve assembly, including:
[0537] Control element, first pipe, first inlet and first outlet;
[0538] The control element is used to control the first inlet to connect with one end of the first pipe, and the other end of the first pipe to connect with the first outlet; the first inlet is used to dock or disconnect with the first interface of the reagent kit, so that when docking, the control element controls the first inlet to obtain the fluid of the reagent kit; and the first outlet is used to connect with the docking slot of the reagent kit, so that when docking, the liquid of the reagent kit can reach the docking slot through the first outlet, and the liquid in the docking slot can reach the recycling pack of the reagent kit through the second pipe of the reagent kit.
[0539] The valve assembly further includes a third pipe, a third inlet, and a third outlet. The control element is used to control the third inlet to be connected to one end of the third pipe, and the other end of the third pipe to be connected to the third outlet.
[0540] The third inlet is used to dock with or detach from the second interface of the reagent kit, and the third outlet is used to communicate with the sampling end of the sampling element so that when docked, the liquid of the reagent kit can reach the sampling element through the third outlet.
[0541] The valve assembly has a first vent and a second vent, and one end of the first pipe is selectively connected to the first inlet or the first vent under the control of the control element; one end of the third pipe is selectively connected to the third inlet or the second vent under the control of the control element.
[0542] Another aspect of this application provides a reagent kit, comprising:
[0543] The cavity, the second pipe, the first interface, and the docking groove;
[0544] The cavity is used to hold the reagent pack and the recovery pack. One end of the second pipe is connected to the recovery pack, and the other end is connected to the docking groove. The first interface is used to dock with or separate from the first inlet of the valve assembly. The docking groove is used to connect with the first outlet of the valve assembly so that when docking, the liquid in the reagent pack can be transported to the delivery valve assembly through the first interface. The liquid in the docking groove can reach the recovery pack through the second pipe.
[0545] The docking groove is provided with an inlet hole and an outlet hole. The inlet hole is used to communicate with the first outlet of the valve assembly, and the outlet hole is used to communicate with the second pipe.
[0546] The docking groove is provided with an isolation section located between the liquid inlet and the liquid outlet, and a flow channel connecting the liquid inlet and the liquid outlet and bypassing the isolation section.
[0547] The reagent kit also has a fourth pipe and a second interface. The second interface is used to connect the third inlet of the valve assembly and the reagent pack. The third outlet is used to connect to the sampling end of the sampling element. One end of the fourth pipe is used to connect to the sample outlet of the sampling element, and the other end is used to connect to the detection component of the fluid detection instrument.
[0548] The docking groove is provided with a through hole and a connecting pipe passing through the through hole. One end of the connecting pipe is connected to the third outlet, and the other end is used to connect to the sampling end of the sampling element. The connecting pipe is in sealed contact with the hole wall of the through hole.
[0549] The sampling element includes a sampling needle, a sleeve fitted on the sampling needle, and a docking member at the end of the sleeve. The outer diameter of the sleeve does not exceed the inner diameter of the docking groove, and the docking member has a through hole. The docking member can move along the axial direction of the sampling needle with the sleeve so that the sampling needle is inserted into one end of the through hole or passes through the through hole and is exposed on one side of the docking member.
[0550] Wherein, when the sleeve moves along the axial direction of the sampling needle and toward the connecting tube so that the docking member is inserted into the docking groove, the sampling needle and the connecting tube are respectively inserted at both ends of the through hole to achieve communication.
[0551] Another embodiment of this application provides a liquid bag having a body and a connector, the body being used to contain liquid, and the connector being configured to control the liquid in the liquid bag to flow out from the connector or to seal the body.
[0552] The connector has a pipe that connects to the internal space of the body and a sealing element disposed in the pipe. The sealing element can move inside the pipe to open the pipe under the action of external force, and return to its initial position to seal the pipe when the external force is removed.
[0553] The pipe has a first abutting portion, and the seal has a second abutting portion; wherein, when the seal is in its initial position, the first abutting portion abuts against the second abutting portion to seal the pipe; the seal moves within the pipe under the action of an external force to separate the first abutting portion and the second abutting portion to open the pipe.
[0554] The pipeline includes a first pipeline and a second pipeline that are connected to each other. One end of the first pipeline is connected to the body and the other end is connected to the second pipeline. The inner diameter of the first pipeline is larger than the inner diameter of the second pipeline to form a stepped first abutment at the connection between the first pipeline and the second pipeline. The sealing element has a gap with the first pipeline, and the second abutment can seal the end of the second pipeline that is connected to the first pipeline.
[0555] Wherein, the outer diameter of the seal is smaller than the inner diameter of the first pipe, and the outer diameter of the seal is larger than the inner diameter of the second pipe; the seal is disposed inside the first pipe in the initial position, and the end of the seal near the second pipe forms a second abutting portion to abut against the first abutting portion.
[0556] The sealing element has a sealing portion and a guiding portion. The outer diameter of the sealing portion is larger than the outer diameter of the guiding portion. The outer diameter of the sealing portion is smaller than the inner diameter of the first pipe. The outer diameter of the sealing portion is larger than the inner diameter of the second pipe. In the initial position, the sealing portion is located inside the first pipe, and the end of the sealing portion near the second pipe forms a second abutting portion to abut against the first abutting portion. The guiding portion is located inside the second pipe and has a gap with the second pipe. The guiding portion is used to receive the external force.
[0557] The first pipe has a limiting part at the end opposite to the second pipe, and the limiting part is used to restrict the sealing part from entering the body.
[0558] The connector has a mating interface, which is located at the end of the second pipe opposite to the first pipe and is connected to the second pipe; the mating interface is used to guide the external connector into the pipe to apply force to the seal.
[0559] The interface is provided with a sealing ring. At least part of the end of the guide portion is exposed outside the liquid bag from the annular hollow portion of the sealing ring. The external connector can enter the pipeline from the annular hollow portion of the sealing ring to apply force to the seal. When the external connector abuts against the guide portion and pushes the guide portion to move towards the first pipeline, the sealing ring can seal the gap between the external connector and the interface.
[0560] The sealing ring includes a first sealing ring and a second sealing ring. The first sealing ring is disposed between the guide portion and the second sealing ring. The external connector can apply force to the guide portion through the first sealing ring and the second sealing ring.
[0561] The first sealing ring and the second sealing ring are coaxially arranged, and the outer diameter of the first sealing ring is smaller than the outer diameter of the second sealing ring.
[0562] Wherein, both the first sealing ring and the second sealing ring are elastic bodies, and the external connector can enter the pipe through the annular hollow portion of the first sealing ring and the second sealing ring to apply force to the sealing element;
[0563] When the external connector applies force to the seal, the external connector is sealed and assembled with at least one of the first sealing ring and the second sealing ring.
[0564] The second sealing ring has a guide slope at the end opposite to the first sealing ring, and the guide slope is used to guide the external connector into place.
[0565] Another aspect of this application provides an integrated reagent kit, comprising:
[0566] A housing and a sampling component disposed on the housing;
[0567] The sampling component includes a rotating component rotatably connected to the housing and a sampling component connected to the rotating component;
[0568] The rotating component can change its state under the action of a first external force to drive the sampling component to rotate synchronously relative to the box, and can restore its state when the first external force is removed.
[0569] The sampling element includes a sampling needle and a sleeve fitted on the sampling needle. The sleeve can change its state under the action of a second external force to move relative to the rotating element to expose the sampling needle, and can return to its original state to cover the sampling needle when the second external force is removed.
[0570] The rotating component includes a first rotating part and a second rotating part connected to each other. The first rotating part is movably connected to the sleeve in the axial direction of the sleeve, and the second rotating part is rotatably connected to the box body. The first rotating part is used to receive the first external force.
[0571] The integrated reagent kit includes a first elastic element connecting the first rotating part and the sleeve. When the sleeve is moved under force, the first elastic element changes its state to generate elastic force. When the force on the sleeve is removed, the first elastic element returns to its original state under the action of elastic force so that the sleeve returns to its original state.
[0572] The sampling needle has a sampling part and a sample outlet part that are bent and connected. The sleeve is sleeved on the sampling part and can move along the axial direction of the sampling part. The sample outlet part extends from one end of the sampling part to the second rotating part or extends and passes through the second rotating part. The sleeve is provided with a clearance groove to avoid the sample outlet part when the sleeve moves along the axial direction.
[0573] The end of the sleeve adjacent to the sampling end of the sampling section has an enlarged portion, which pushes the sleeve to move under the action of a second external force applied by the external container when the sampling needle obtains liquid in the external container.
[0574] The sleeve is inserted through the first rotating part, and one end of the sleeve is connected to the first rotating part through the first elastic member.
[0575] The integrated reagent kit includes a second elastic element that acts between the second rotating part and the box body. When the rotating part rotates relative to the box body under the action of a first external force, it changes the state of the second elastic element to generate elastic force. When the first external force is removed, the second elastic element causes the rotating part to return to its original state under the action of elastic force.
[0576] The box body is provided with a rotating groove, the second rotating part is inserted into the rotating groove, the second elastic member is sleeved on the second rotating part and the end of the second elastic member abuts against the rotating groove; the sampling needle can be connected to the pipe on the box body through the rotating groove.
[0577] The box body is provided with an assembly part, which is located near the corner area of the box body. The rotating groove is formed in the assembly part, and the second rotating part is inserted into the rotating groove so that the sampling end of the sampling component can rotate out of the corner area of the box body when the sampling component rotates.
[0578] Another aspect of this application provides a reagent kit that is easy to clean, comprising:
[0579] The container comprises a box body, a first pipe, a second pipe, and a docking groove; the box body contains a reagent pack and a recycling pack; one end of the first pipe is connected to the docking groove and the other end is connected to the reagent pack; one end of the second pipe is connected to the docking groove and the other end is connected to the recycling pack.
[0580] The docking groove is used to dock with or separate from the sampling element. During docking, the liquid in the reagent pack can reach the docking groove through the first pipe and clean the sampling end of the sampling element. The cleaned liquid can reach the recovery pack through the second pipe.
[0581] The docking groove has an inlet connected to the first pipe and an outlet connected to the second pipe. When the docking groove is docked with the sampling element, the sampling end of the sampling element seals the docking groove and cooperates with the docking groove to form a cavity. The inlet and the outlet are respectively connected to the cavity.
[0582] The docking groove includes a first groove segment and a second groove segment that are axially connected. The first groove segment is located away from the bottom of the docking groove relative to the second groove segment. The first groove segment is used to dock with or separate from the sampling element. The second groove segment has the liquid inlet and the liquid outlet. The inner diameter of the first groove segment is larger than the inner diameter of the second groove segment, and the inner diameter of the first groove segment is larger than the outer diameter of the sampling end. The inner diameter of the second groove segment is smaller than the outer diameter of the sampling end.
[0583] The sampling element includes a sleeve, a sampling needle and a connector disposed within the sleeve, the connector having a through hole, the connector being embedded at one end of the sleeve, and the sampling end of the sampling needle being inserted into the through hole; when the docking groove is docked with the sampling element, the sleeve abuts against the first groove segment, the connector abuts against the second groove segment, and the cavity is formed between the connector and the second groove segment.
[0584] The second groove segment has an open end and a narrow end that are arranged opposite to each other, wherein the inner diameter of the open end is larger than the inner diameter of the narrow end; wherein the inner diameter of the open end is larger than the outer diameter of the connector and smaller than the outer diameter of the sleeve.
[0585] Wherein, the inner diameter of the narrow end does not exceed the inner diameter of the sleeve.
[0586] The reagent kit has a third channel partially located within the docking groove. When the docking groove is docked with the sampling element, the connector is inserted into the second groove segment, and the third channel is inserted into the connector to communicate with the sampling needle.
[0587] The connector abuts against the end of the second groove segment and has a groove. The through hole connects to the bottom wall of the groove. The connector is in sealed contact with the side wall of the second groove segment. The groove and the second groove segment form a cavity that can clean the sampling end.
[0588] The second tank section is provided with an isolation section. The liquid inlet and the liquid outlet are located on opposite sides of the isolation section and are respectively connected to the cavity, so that the liquid in the reagent pack can reach the cavity from the liquid inlet and clean the sampling end of the sampling element. The cleaned liquid flows out of the cavity from the liquid outlet and reaches the recovery pack through the second pipe.
[0589] The sampling element includes a sleeve and a sampling needle and a connector disposed within the sleeve. The connector has a through hole and is embedded at one end of the sleeve. The sampling end of the sampling needle is inserted into the through hole. The inner wall of the sleeve has a stepped portion, and the connector has a snap-fit portion. The snap-fit portion is located on the side of the stepped portion away from the bottom wall of the mating groove and abuts against the stepped portion, so that the connector can move axially with the sleeve.
[0590] Another embodiment of this application provides a sample analysis device, including:
[0591] The reagent kit includes a sampling component, an adjustment component, and a moving component. The adjustment component is used to drive the sampling component to rotate relative to the reagent kit. The moving component is positioned corresponding to the sampling component. The moving component and the sampling component can be docked or detached.
[0592] The moving component is movable relative to the sampling component between a first position and a second position. At the first position, the moving component is docked with the sampling component, and at the second position, the moving component is separated from the sampling component.
[0593] The first position corresponds to limiting the sampling component so that the sampling component can collect liquid inside the reagent kit, and the second position corresponds to releasing the limitation on the sampling component so that the adjustment component can drive the sampling component to rotate, thereby enabling the sampling component to collect liquid outside the reagent kit.
[0594] The reagent kit has a box for holding a liquid package, and the box has a first interface and a second interface. The first interface is used to dock with the detection component, and the second interface is used to dock with the liquid package. The moving component has a third interface. One end of the sampling component is connected to the first interface through a first liquid path, and the other end can be selectively docked with or separated from the third interface. The second interface is connected to the third interface through a second liquid path.
[0595] The adjustment assembly has a base and a shaft on the base. The sampling assembly includes a sampling element, one end of which is at least partially located inside the base and connected to the first interface through the first liquid path, and the other end is located outside the base for selectively docking or separating from the third interface. The shaft is docked with the housing and is rotatable relative to the housing.
[0596] The sampling assembly further includes a sleeve fitted onto the sampling element, the sleeve being movable upward along the axial direction of the sampling element; wherein the sleeve is provided with a clearance groove to avoid the first liquid path or the sampling element during the movement of the sleeve.
[0597] The sleeve has an enlarged portion at the end adjacent to the moving component. When the sampling element acquires liquid from the external container, the enlarged portion is pushed by the external container to move the sleeve.
[0598] The sampling assembly includes a first elastic element assembled between the sleeve and the base. When the sleeve is moved by force, the first elastic element changes its state to generate elastic force. When the force on the sleeve is removed, the first elastic element returns to its state under the action of elastic force so that the sleeve is reset and the sampling end of the sampling element is blocked.
[0599] The sampling component includes a second elastic element assembled between the adjustment component and the housing. When the adjustment component is subjected to force and rotates relative to the housing, it changes the state of the second elastic element to generate elastic force. When the force on the adjustment component is removed, the second elastic element returns to its original state under the action of elastic force, thereby resetting the adjustment component.
[0600] The base is provided with a docking part, which is used to engage with the first drive component when docking with the first drive component of the sample analysis device; the moving component is used to dock with or separate from the sampling element under the drive of the second drive component when docking with the second drive component of the sample analysis device.
[0601] The sample analysis device further includes a mounting bracket, which has a cavity, a first mounting position, and a second mounting position. The reagent kit can be moved into or out of the cavity. The first mounting position is used to install the first driving component, and the second mounting position is used to install the second driving component.
[0602] When the reagent kit is moved into the cavity, the docking part docks with the first driving component, and the moving component docks with the second driving component.
[0603] The first drive assembly includes a first power component mounted on the first mounting position, and the docking portion of the seat is provided with a shaft hole; wherein, when the docking portion docks with the first drive assembly, the output shaft of the first power component cooperates with the shaft hole to realize the transmission cooperation between the docking portion and the first power component.
[0604] The movable component includes a docking seat that is movable relative to the housing. One end of the docking seat has the third interface, and the other end is used to dock with the second driving component. When the reagent kit is moved into the cavity, the docking seat docks with the second driving component to move under the drive of the second driving component.
[0605] The second drive component includes a second power component mounted on the second mounting position and a locking component that engages with the output shaft of the second power component. The second power component can drive the locking component to move.
[0606] When the reagent kit is moved into the cavity, the engaging member engages with the docking seat, so that the second power member drives the docking seat to move synchronously when driving the engaging member to move.
[0607] Another embodiment of this application provides a biological sample analysis device, including:
[0608] Drive component, with output shaft;
[0609] A reagent storage device includes a storage cavity, a first connecting pipe, a second connecting pipe, and a squeezing assembly. The storage cavity is used to hold reagent packs, cleaning packs, and recycling packs. Both the first and second connecting pipes are partially embedded in the squeezing assembly. One end of the first connecting pipe is connected to the reagent pack, and the other end is connected to the recycling pack. One end of the second connecting pipe is connected to the cleaning pack, and the other end is connected to the recycling pack.
[0610] The drive assembly and the reagent storage device can be docked or separated, so that the output shaft can dock or separate from the extrusion assembly; when docked, the output shaft can drive the extrusion assembly to extrude the first connecting pipe and the second connecting pipe synchronously so that the liquid in the first connecting pipe or the second connecting pipe can flow.
[0611] The biological sample analysis device further includes a mounting bracket, which has a cavity and a first mounting position. The reagent storage device can be moved into or out of the cavity, and the drive component is installed at the first mounting position. The first mounting position is located at the end of the travel distance when the reagent storage device moves into the cavity.
[0612] The drive assembly is located outside the cavity, and there is a clearance hole between the cavity and the first mounting position. The output shaft of the drive assembly extends into the cavity through the clearance hole. When the reagent storage device is moved into the cavity, the output shaft of the drive assembly is driven and assembled with the extrusion assembly.
[0613] The extrusion assembly includes a first extruder and a second extruder. The second extruder is embedded in the first extruder and coaxially arranged with the first extruder. The first connecting pipe and the second connecting pipe are partially disposed between the first extruder and the second extruder. The second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the first connecting pipe and the second connecting pipe.
[0614] The first extruder is annular, and the second extruder has a rotating part and an extruding part. The rotating part is used to dock with the output shaft, and the extruding part is located on the periphery of the rotating part and can rotate synchronously with the rotating part.
[0615] The extrusion section is spaced apart from the first extrusion member, and the first connecting pipe and the second connecting pipe are partially located between the extrusion section and the first extrusion member.
[0616] The rotating part has a shaft hole, one end of the output shaft is assembled with the shaft hole, and the portions of the first connecting pipe and the second connecting pipe disposed between the extrusion part and the first extruder are arranged along the axial direction of the shaft hole.
[0617] The extrusion section is fitted with a bushing, and the bushing is provided with a spacer, which is located between the first connecting pipe and the second connecting pipe.
[0618] The cavity wall of the receiving chamber is provided with a receiving groove, and the extrusion assembly is embedded in the receiving groove and coaxially arranged with the receiving groove. The first connecting pipe and the second connecting pipe are partially disposed between the receiving groove and the extrusion assembly. The extrusion assembly is used to drive the output shaft to rotate relative to the receiving groove under the drive of the output shaft, thereby extruding the first connecting pipe and the second connecting pipe.
[0619] Another aspect of this application provides a reagent storage device, including:
[0620] The container includes a receiving cavity, a first connecting pipe, a second connecting pipe, and an extrusion assembly.
[0621] The storage cavity is used to hold reagent packs, cleaning packs, and recycling packs. Both the first connecting pipe and the second connecting pipe are partially embedded in the extrusion assembly. One end of the first connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recycling pack. One end of the second connecting pipe is used to connect to the cleaning pack, and the other end is used to connect to the recycling pack.
[0622] The extrusion assembly is used to dock with or disconnect from the output shaft of the drive assembly, so that when docking, the output shaft drives the extrusion assembly to synchronously extrude the first connecting pipe and the second connecting pipe so that the liquid in the first connecting pipe or the second connecting pipe can flow.
[0623] The extrusion assembly includes a first extruder and a second extruder. The second extruder is embedded in the first extruder and coaxially arranged with the first extruder. The first connecting pipe and the second connecting pipe are partially disposed between the first extruder and the second extruder. The second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the first connecting pipe and the second connecting pipe.
[0624] The first extruder is annular, and the second extruder has a rotating part and an extruding part. The rotating part is used to dock with the output shaft, and the extruding part is located on the periphery of the rotating part and can rotate synchronously with the rotating part.
[0625] The extrusion section is spaced apart from the first extrusion member, and the first connecting pipe and the second connecting pipe are partially located between the extrusion section and the first extrusion member.
[0626] The rotating part has a shaft hole, one end of the output shaft is assembled with the shaft hole, and the portions of the first connecting pipe and the second connecting pipe disposed between the extrusion part and the first extruder are arranged along the axial direction of the shaft hole.
[0627] The extrusion section is fitted with a bushing, and the bushing is provided with a spacer, which is located between the first connecting pipe and the second connecting pipe.
[0628] The cavity wall of the receiving chamber is provided with a receiving groove, and the extrusion assembly is embedded in the receiving groove and coaxially arranged with the receiving groove. The first connecting pipe and the second connecting pipe are partially disposed between the receiving groove and the extrusion assembly. The extrusion assembly is used to drive the output shaft to rotate relative to the receiving groove under the drive of the output shaft, thereby extruding the first connecting pipe and the second connecting pipe.
[0629] Another embodiment of this application provides a biological parameter analysis device, including:
[0630] A housing, the housing having a window and a door capable of concealing the window;
[0631] A reagent kit, removable into or out of the housing, comprising a sampling component and a docking component, wherein when the reagent kit is located within the housing, the sampling component is rotatable from the window to collect liquid outside the housing; the docking component is dockable with the sampling component to enable the sampling component to collect liquid inside the reagent kit; and
[0632] The linkage component links the door and the docking component to drive the door to block the window when the sampling component and the docking component are docked, and to drive the door to open the window when the sampling component and the docking component are separated.
[0633] The housing includes an outer shell and a bracket disposed within the outer shell. The window is disposed on the outer shell, and the door is disposed on the inner side of the housing. The bracket has a cavity and a first mounting position. The reagent kit can be moved into or out of the cavity. The first mounting position is disposed at the end of the travel distance when the reagent kit moves into the cavity. When the reagent kit moves into the cavity, the docking component is disposed corresponding to the first mounting position. The linkage component is partially assembled to the first mounting position and partially assembled to the outer shell.
[0634] The bracket includes a frame plate and a mounting plate disposed on one side of the frame plate. The frame plate and the mounting plate cooperate to form the cavity. There is a clearance between the frame plate and the mounting plate to avoid the linkage component and the sampling component. The clearance is disposed opposite to the door. The linkage component drives the door to open the window and simultaneously drives the sampling component to separate from the docking component. The sampling end of the sampling component can be rotated out from the window.
[0635] The linkage component includes a driving component and a first linkage component. The driving component is installed at the first mounting position, and the first linkage component is located at the output end of the driving component. When the reagent kit is moved into the cavity, the first linkage component docks with the docking component. The driving component is used to drive the first linkage component to move the docking component and to drive the first linkage component to move the door.
[0636] The driving component and the first linkage component are located on opposite sides of the frame plate, and the driving component is located outside the cavity.
[0637] The first linkage component includes a first docking part and a first linkage part. The first docking part is used to dock with the docking component, and the first linkage part is used to link with the door.
[0638] The linkage component includes a second linkage component installed on the outer shell, one end of which is connected to the first linkage part, and the other end of which is connected to the door.
[0639] The second linkage component includes a second linkage member and a transmission component that is pulsatorically connected to the second linkage member. The second linkage member is connected to the first linkage part to move relative to the outer shell under the action of the first linkage part. The moving direction of the second linkage member is perpendicular to the direction in which the door opens or closes.
[0640] The transmission assembly includes a first transmission component that is driven by the second linkage component, a second transmission component that is driven by the first transmission component, a third transmission component that is driven by the second transmission component, and a fourth transmission component that is rotatably connected to the third transmission component. The fourth transmission component is assembled with the door.
[0641] Wherein, the movement of the second linkage component drives the rotation of the first transmission component, the second transmission component rotates synchronously with the first transmission component, the rotation of the second transmission component drives the movement of the third transmission component, the movement of the third transmission component drives the rotation of the fourth transmission component, the door rotates synchronously with the fourth transmission component, and the movement direction of the third transmission component is perpendicular to the movement direction of the second linkage component.
[0642] The linkage component includes a base mounted on the housing, and the second linkage member is slidably connected to the base. One of the second linkage member and the base is provided with a travel groove, and the other is provided with a limiting block. The limiting block slides in the travel groove to limit the sliding travel of the second linkage member relative to the base.
[0643] A first elastic element is provided between the second linkage member and the seat. When the second linkage member moves relative to the outer shell under the action of the first linkage part, the first elastic element changes shape to generate elastic force. When the action of the first linkage part is removed, the first elastic element restores its shape to cause the second linkage member to return to its position.
[0644] The fourth transmission member is rotatably connected to the seat, and a second elastic member is provided between the fourth transmission member and the seat. When the third transmission member drives the fourth transmission member to rotate, thereby causing the door to open the window, the second elastic member changes shape to generate elastic force. When the force exerted by the third transmission member on the fourth transmission member is removed, the fourth transmission member drives the door to cover the window under the action of elastic force.
[0645] Another embodiment of this application provides a sample parameter analysis device, including:
[0646] A housing, the housing having a window and a door capable of concealing the window; the housing having a first side and a second side disposed opposite to each other, the door being disposed on the first side and rotatably connected to the housing; and
[0647] A connecting assembly is disposed on the second side of the housing to connect the housing and the door when the door obscures the window; the connecting assembly includes a locking member, a driving member, and a first elastic member, one end of the first elastic member being connected to the middle of the locking member and the other end being connected to the housing, one end of the locking member being connected to the driving member and the other end being used to restrict the position of the door when the door obscures the window;
[0648] The driving member is used to drive the engaging member to move to release the restriction on the door, so that the door can rotate relative to the housing and open the window. When the engaging member moves, the first elastic member deforms to generate elastic force. The elastic force is used to act on the engaging member when the driving member releases its drive to the engaging member, so that the engaging member returns to its original position.
[0649] The second side of the housing is provided with a locking groove, and the door is provided with a locking part on the side near the housing. The locking part can move into or out of the locking groove. When the locking part moves into the locking groove, the locking member abuts against the locking part to restrict the position of the door.
[0650] The engaging member has a protrusion at one end and a groove on the engaging part. When the engaging part moves into the engaging groove, the protrusion is inserted into the groove to restrict the position of the door.
[0651] The engaging groove has a first slot and a second slot located on adjacent sides of the engaging groove. The first slot is used for the engaging part to move in or out, and the second slot is used for the protrusion to move in or out.
[0652] When the engaging portion moves from the first slot into the engaging groove, the engaging portion pushes the protrusion out of the second slot; the protrusion can move into the engaging groove or the recess under the elastic force of the first elastic member.
[0653] At least one of the engaging portion and the protrusion is provided with a guide slope, which is used to guide the engaging portion to push the protrusion out of the second slot when the engaging portion moves into the engaging groove.
[0654] The engaging groove has a first sidewall and a second sidewall spaced apart. The first sidewall and the second sidewall are respectively connected to the housing. The engaging member can rotate around the first sidewall so that the protrusion can move into or out between the first sidewall and the second sidewall.
[0655] The engaging member is rotatable around the first sidewall. The engaging member has a protruding end and an end that connects to the driving member located on both sides of the first sidewall. One end of the first elastic member is connected between the two ends of the engaging member.
[0656] The connecting component further includes a second elastic element disposed on the engaging groove. When the engaging part moves into the engaging groove, the engaging part squeezes or stretches the second elastic element, causing the second elastic element to deform and generate elastic force. When the driving member drives the engaging member to release the restriction on the door, the elastic force acts on the door, causing the door to rotate relative to the housing to open the window.
[0657] The engaging groove has a third sidewall spaced apart from the housing. The connecting assembly includes a top support that passes through the third sidewall. The second elastic member acts between the top support and the third sidewall. When the engaging part moves into the engaging groove, it pushes the top support to move, thereby changing the state of the second elastic member to generate elastic force.
[0658] The third sidewall is provided with a storage groove, and the top holding member is provided with a limiting part. One end of the top holding member is inserted into the storage groove for connecting the second elastic member. The limiting part is located in the storage groove to limit the movement stroke of the top holding member when the engaging part pushes the top holding member to move.
[0659] The connecting component includes a limiting member located on the second side of the housing, and the engaging member is located between the limiting member and the housing.
[0660] Another embodiment of this application provides a sample analysis kit, including:
[0661] The seat has a first cavity, a second cavity, and an isolator, the isolator being configured to connect or isolate the first cavity and the second cavity, wherein when the first cavity and the second cavity are connected, liquid in the first cavity can flow to the second cavity;
[0662] The isolator can change its state under the action of an external force to make the first cavity and the second cavity conductive. When the external force is removed, the isolator returns to its original state to isolate the first cavity and the second cavity.
[0663] The seat has a first liquid port for connecting the first cavity and the second cavity. The isolating member is disposed on the cavity wall of the first cavity corresponding to the location of the first liquid port and is used to open or block the first liquid port. When the isolating member is not subjected to external force, it blocks the first liquid port to isolate the first cavity and the second cavity. When the isolating member is subjected to external force, it opens the first liquid port to allow the first cavity and the second cavity to be connected through the first liquid port.
[0664] The first cavity has a squeezing member on its cavity wall. The squeezing member abuts against the isolation member and is used to apply force to the isolation member so that the isolation member opens the first liquid port.
[0665] The first cavity has a compression port, and the compression member is sealed and assembled with the compression port. The compression member extends into the first cavity from the compression port to abut against the isolation member and can apply force to the isolation member.
[0666] The isolation component includes a connecting part and an isolation part. The connecting part is connected to the cavity wall of the first cavity. One end of the isolation part is connected to the connecting part, and the other end is used to abut against the extrusion component. Under the action of external force, the isolation part can move relative to the connecting part to open the first liquid port. When the external force is removed, the isolation part returns to its original state to block the first liquid port.
[0667] At least one of the isolation portion and the connecting portion is provided with an elastic element. The elastic element is disposed between the connecting portion and the isolation portion. When the isolation portion is subjected to an external force, it squeezes the elastic element to deform and generate elastic force. When the external force is removed, the elastic force causes the isolation portion to return to its original state.
[0668] The isolation section is provided with a sealing element on the side near the first liquid outlet. When the isolation section returns to its original state to cover the first liquid outlet, the sealing element is sealed and assembled with the first liquid outlet.
[0669] The connecting part is fixed to the cavity wall of the first cavity, and the isolation part is rotatably connected to the connecting part through a rotating shaft.
[0670] The extrusion component includes an assembly part and an extrusion part. The assembly part is used to assemble the extrusion component onto the extrusion port. The assembly part is annular, and the extrusion part is located in the annular hollow area of the assembly part and is elastically connected to the assembly part. The assembly part is sealed and assembled with the extrusion port.
[0671] The base has a third cavity and a salt bridge, one end of which is exposed to the second cavity, and the other end of which is exposed to the third cavity and connected to an electrode terminal located in the third cavity.
[0672] Another aspect of this application provides a detection component, including:
[0673] The system includes a first liquid passage, a second liquid passage, an inlet, an outlet, and valve assemblies.
[0674] One end of the first liquid path is used to connect to the liquid inlet, and the other end is used to connect to the liquid outlet;
[0675] One end of the second liquid path is used to connect to the liquid inlet, and the other end is used to connect to the liquid outlet;
[0676] The valve assembly is located between the liquid inlet, the liquid outlet, and / or the liquid inlet and the liquid outlet, and can switch between a first conducting state and a second conducting state to control the first liquid path and the second liquid path to be selectively conducting.
[0677] In the first conducting state, the first external liquid of the detection component can flow into the first liquid path from the inlet and flow out of the first liquid path from the outlet.
[0678] In the second conduction state, the second external liquid of the detection component can flow into the second liquid path from the inlet and flow out of the second liquid path from the outlet.
[0679] The first liquid passage has a first inlet and a first outlet, the second liquid passage has a second inlet and a second outlet, and the valve assembly includes a first valve and a second valve; the first inlet and the second inlet are used to communicate with the liquid inlet, and the first outlet and the second outlet are used to communicate with the liquid outlet; the first valve is disposed between the first inlet and the first outlet to control the opening and closing of the first liquid passage, and the second valve is disposed between the second inlet and the second outlet to control the opening and closing of the second liquid passage;
[0680] Either the first valve or the second valve can be turned on.
[0681] The valve assembly further includes a third valve located between the liquid inlet and the second inlet, used to control the opening and closing of the liquid inlet and the second inlet; wherein the third valve and the first valve can be selectively activated.
[0682] The first liquid path includes a first inlet section and a first outlet section, the first inlet section being connected to the inlet port and the first outlet section being connected to the outlet port; the first valve is disposed between the first inlet section and the first outlet section to control the opening and closing of the first inlet section and the first outlet section, and the third valve is disposed between the second inlet and the first inlet section to control the opening and closing of the second inlet and the first inlet section.
[0683] The detection component includes a housing and a plate. The plate has a first through-hole and a second through-hole. The housing has a cavity, and the sidewall of the cavity has a first fluid groove and a second fluid groove. The plate is located inside the cavity. The first through-hole connects to a portion of the first fluid groove, and the second through-hole connects to a portion of the second fluid groove. The plate closes off another portion of the first fluid groove and another portion of the second fluid groove to form a first liquid path and a second liquid path. The inlet and outlet are respectively connected to the cavity. The valve assembly is located outside the cavity. The first valve controls the opening and closing of the first liquid path, and the second valve controls the opening and closing of the second liquid path.
[0684] The housing includes a first housing and a second housing that surround the cavity, and the first housing and the second housing cooperate to clamp the plate to form the first liquid passage and the second liquid passage;
[0685] Wherein, the first housing has a first through hole and a second through hole, the liquid inlet and the first inlet are located at both ends of the first through hole of the first housing, or the liquid inlet and the second inlet are located at both ends of the first through hole of the first housing, and / or;
[0686] The first outlet and the liquid outlet are located at both ends of the second through hole of the first housing, or the second outlet and the liquid outlet are located at both ends of the second through hole of the first housing.
[0687] The second housing has a receiving cavity, and the first housing is at least partially embedded in the receiving cavity and cooperates with the second housing to form the cavity. The pipe is disposed between the first housing and the second housing.
[0688] The shell is provided with a first groove and a second groove, a first liquid inlet channel and a first liquid outlet channel respectively connected to the first groove, and a second liquid inlet channel and a second liquid outlet channel respectively connected to the second groove;
[0689] The first liquid path located between the first inlet and the first outlet includes two discontinuous first sub-liquid paths. One end of the first inlet channel is connected to the first inlet, and one end of the first outlet channel is connected to the first outlet. The two first sub-liquid paths are connected through the first tank, the first inlet channel, and the first outlet channel.
[0690] The second liquid passage located between the second inlet and the second outlet includes two discontinuous second sub-liquid passages. One end of the second inlet channel is connected to the second inlet, and one end of the second outlet channel is connected to the second outlet. The two second sub-liquid passages are connected through the second tank, the second inlet channel, and the second outlet channel.
[0691] The first valve is an elastic body, disposed on the housing, and under the action of external force, it can abut against the first groove to block the first liquid inlet channel and the first liquid outlet channel, thereby disconnecting the first liquid path; the second valve is an elastic body, disposed on the housing, and under the action of external force, it can abut against the second groove to block the second liquid inlet channel and the second liquid outlet channel, thereby disconnecting the second liquid path.
[0692] The housing is provided with a third groove, a third valve, and a third liquid inlet channel and a third liquid outlet channel that are respectively connected to the third groove;
[0693] Wherein, the first liquid path and the second liquid path are not continuous, one end of the third liquid inlet channel is connected to the first inlet, one end of the third liquid outlet channel is connected to the second inlet, and the first liquid path and the second liquid path are connected through the third tank, the third liquid inlet channel and the third liquid outlet channel;
[0694] The third valve is an elastic body that can be pressed against the third groove under external force to block the third liquid inlet channel and the third liquid outlet channel, thereby disconnecting the first liquid path and the second liquid path.
[0695] The first valve, the second valve, and the third valve are an integral structure.
[0696] The following describes a blood gas analysis device that utilizes blood gas analysis technology. Blood gas analysis technology refers to a technique applied to blood gas analysis equipment that measures the concentration of H+ and dissolved gases (mainly CO2, O2, etc.) in a blood sample to understand the human body's respiratory function and acid-base balance. It can directly reflect lung gas exchange function and its acid-base balance, and the specimen used is usually a blood sample.
[0697] Please see Figure 1 , Figure 1 This is a schematic diagram of the structure of a blood gas analysis device 1 in one embodiment of this application. The blood gas analysis device 1 generally includes: a first detection component 101, having a detection element 1011, a first liquid path 1012 and a first interface 1013, wherein the first liquid path 1012 and the first interface 1013 are connected, and the detection element 1011 is used to perform blood gas detection on the liquid in the first liquid path 1012; and a reagent kit 103, having a cavity 1031, a second liquid path 1032 and a second interface 1033, wherein the cavity 1031 is used to place a liquid bag 1030, one end of the second liquid path 1032 is used to connect to the liquid bag 1030, and the other end is connected to the second interface 1033.
[0698] The first detection component 101 and the reagent kit 103 can be docked or separated, so that the first interface 1013 and the second interface 1033 can be connected or separated. When connected, the first liquid path 1012 connects to the second liquid path 1032 so that the reagent in the liquid package 1030 can reach the first liquid path 1012. When the reagent kit 103 is moved into the mounting bracket 105 of the blood gas analyzer 1, the first interface 1013 and the second interface 1033 are connected.
[0699] The reagent kit 103 is equipped with a sampling element 1034. The sampling end of the sampling element 1034 is used to selectively collect the reagent in the liquid package 1030 or the external liquid of the reagent kit 103. The sampling outlet end of the sampling element 1034 is used to connect to the second interface 1033. When collecting the reagent in the liquid package 1030, the sampling element 1034 constitutes part of the second liquid path 1032.
[0700] The reagent kit 103 has a first connecting tube 1035, one end of which is used to connect to the liquid bag 1030 and the other end is used to connect to the sampling end of the sampling element 1034; wherein, the first connecting tube 1035 constitutes another part of the second liquid path 1032.
[0701] The first detection component 101 has a third interface 1014 spaced apart from the first interface 1013, and the third interface 1014 is connected to the first liquid path 1012; the reagent kit 103 has a fourth interface 1036 and a second connecting tube 1037, and the fourth interface 1036 and the second interface 1033 are spaced apart; one end of the second connecting tube 1037 is connected to the fourth interface 1036 and the other end is connected to the cavity 1031; wherein, when the first interface 1013 and the second interface 1033 are connected, the third interface 1014 and the fourth interface 1036 are connected.
[0702] The cavity 1031 has a docking seat 1038 on the outer side of its cavity wall, and the second interface 1033 and the fourth interface 1036 are located on the docking seat 1038. The second connecting pipe 1037 is located between the cavity wall of the cavity 1031 and the docking seat 1038.
[0703] The liquid package 1030 includes a reagent package 1030a and a recovery package 1030b placed in a cavity 1031. One end of the first connecting tube 1035 is used to connect the reagent package 1030a, and one end of the second connecting tube 1037 is used to connect the recovery package 1030b.
[0704] The reagent kit 103 is provided with a liquid line 1039 exposed in the cavity 1031. The liquid line 1039 constitutes another part of the second liquid line 1032. The liquid flowing out of the first liquid line 1012 flows through the liquid line 1039 and reaches the cavity 1031.
[0705] The blood gas analyzer 1 includes a second detection component 102 mounted on a mounting bracket 105. The second detection component 102 is used to detect the liquid in the liquid pipeline 1039 exposed outside the cavity 1031. The first detection component 101 is used to perform blood gas detection, and the second detection component 102 is used to perform blood oxygen detection.
[0706] It should be noted that the terms "first," "second," and "third," etc., used in this document are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first," "second," or "third" may explicitly or implicitly include one or more of the stated features.
[0707] Please see Figure 2 , Figure 2This is a schematic diagram of the structure of the detection component 2 in one embodiment of this application. The detection component 2 generally includes a housing 201, a detection element 202 and a first liquid passage 203 disposed within the housing 201, and a first interface 204 and a connection terminal on the housing 201. The connection terminal is electrically connected to the detection element 202. The first liquid passage 203 and the first interface 204 are connected, and the detection element 202 is used to perform blood gas detection on the liquid in the first liquid passage 203. The first interface 204 is used to dock with or detach from the second interface of the reagent kit, so that the reagents of the reagent kit can be obtained through the first interface 204 during docking. Furthermore, during docking, the connection terminal is used to electrically connect to the processing circuit of the blood gas analysis device 1.
[0708] The first interface 204 has a tapered recess or tapered protrusion at the end where it mates with the second interface, to guide the second interface 204 to mate with the first interface. The housing 201 has a third interface 205 spaced apart from the first interface 204, and the third interface 205 is connected to the first liquid passage 203.
[0709] The housing 201 is provided with a positioning element 206 for positioning with the bracket on the blood gas analyzer 1 on which the detection component 2 is installed.
[0710] Please see Figure 3 , Figure 3 This is a schematic diagram of the structure of a reagent kit 3 in one embodiment of this application. The reagent kit 3 generally includes a cavity 301, a second liquid path 302, and a second interface 303.
[0711] The cavity 301 is used to hold the liquid pack 304. One end of the second liquid path 302 is connected to the liquid pack 302, and the other end is connected to the second interface 303. The second interface 303 is used to dock with or disconnect from the first interface of the first detection component, so that when docking, the reagent in the liquid pack 304 can be transported to the first detection component through the second interface 303. The reagent kit 3 can be moved into or out of the mounting bracket of the blood gas analyzer. When the reagent kit 3 is moved in, the first interface and the second interface 303 are connected.
[0712] The reagent kit 3 is equipped with a sampling element 305. The sampling end of the sampling element 305 is used to selectively collect the reagent in the liquid package 304 or the external liquid of the reagent kit 3. The sampling outlet end of the sampling element 305 is used to connect to the second interface 303. When collecting the reagent in the liquid package 304, the sampling element 305 constitutes part of the second liquid path 302.
[0713] The reagent kit 3 has a liquid line 306 exposed in the cavity 301. The liquid line 306 constitutes another part of the second liquid line 302. The liquid flowing out of the first detection component flows through the liquid line 306 and reaches the cavity 301. The blood gas analyzer includes a second detection component mounted on a mounting bracket. The second detection component is used to detect the liquid in the liquid line 306 exposed outside the cavity 301. The first detection component is used to perform blood gas detection, and the second detection component is used to perform blood oxygen detection.
[0714] The first detection component has a third interface spaced apart from the first interface; the reagent kit 3 has a fourth interface 307 spaced apart from the second interface 303; wherein, when the first interface and the second interface 303 are connected, the third interface and the fourth interface 307 are connected.
[0715] The cavity 301 has a docking seat 308 on the outer side of its cavity wall, and the second interface 303 and the fourth interface 307 are located on the docking seat 308.
[0716] Please see Figure 4 , Figure 4 This is a schematic diagram of the structure of the mounting bracket 4 of the blood gas analysis device in one embodiment of this application. The mounting bracket 4 generally has a first mounting position 401 and a second mounting position 402. The first mounting position 401 is used for detachably mounting the first detection component, and the second mounting position 402 is used for placing the reagent kit.
[0717] The first detection component and the reagent kit can be docked or separated, so that the first detection component and the reagent kit can be connected or separated. When connected, the reagents in the reagent kit can reach the first detection component.
[0718] The mounting bracket 4 also has a third mounting position 403 for detachably mounting the second detection component; the reagent kit has a liquid line exposed to the cavity from the third mounting position, and the liquid flowing out of the first detection component flows through the liquid line to the cavity; the second detection component is used to detect the liquid in the liquid line exposed outside the cavity, the first detection component is used to perform blood gas detection, and the second detection component is used to perform blood oxygen detection.
[0719] The mounting bracket 4 includes a fixed bracket 404 and a movable bracket 405. The fixed bracket 404 has a cavity forming a second mounting position 402, and the movable bracket 405 has a receiving cavity forming a first mounting position 401. When the reagent kit is moved into the cavity, the movable bracket 405 can move relative to the fixed bracket 404 so that the first detection component can dock with the reagent kit.
[0720] The movable support 405 can move relative to the fixed support along a first direction or a second direction; when the movable support 405 moves relative to the fixed support 404 along the first direction, the first detection component can move into or out of the movable support 405; when the movable support 405 moves relative to the fixed support 404 along the second direction, the first detection component can dock with or separate from the reagent kit.
[0721] The blood gas analysis device provided in this application embodiment allows for the docking or detachment of a first detection component and a reagent kit, enabling detachable assembly and disassembly. During docking, the first liquid path of the first detection component communicates with the second liquid path of the reagent kit, allowing the reagent from the reagent kit to reach the first liquid path for blood gas detection. Furthermore, a mounting bracket is provided for assembling the reagent kit and the first detection component, allowing them to dock or detach upon assembly. During detachment, the reagent kit can be individually disassembled and replaced. Further, a second detection component can be mounted on the mounting bracket. The reagent kit has externally exposed liquid channels, allowing the second detection component to perform blood oxygen detection on the liquid it manages, thus enhancing the detection capabilities of the blood gas analysis device.
[0722] Please see Figure 5 and Figure 6 , Figure 5 This is a structurally exploded schematic diagram of the liquid sample detection device 5 in some embodiments of this application. Figure 6 yes Figure 5 A schematic diagram showing the structural breakdown of the adjusting device 6 in the embodiment.
[0723] The liquid sample detection device 5 generally includes a main body 501 and an adjustment device 6. The main body 501 has a first mounting position 5011; the adjustment device 6 is installed at the first mounting position 5011.
[0724] The adjustment device 6 generally includes a first adjustment component 601 and a second adjustment component 602. The first adjustment component 601 is used to adjust the rotation angle of the sampling element relative to the body 501 of the liquid sample detection device 5, so as to switch between the first fluid path and the second fluid path for conveying liquid.
[0725] The second adjustment component 602 is used to adjust the axial position of the sleeve fitted on the sampling element, so that the sleeve can switch between a first position and a second position. When the sleeve is in the first position, the sampling element can achieve the connection of the first fluid path; when the sleeve is in the second position, the first adjustment component can adjust the rotation angle of the sampling element to achieve the connection of the second fluid path.
[0726] The first adjustment component 601 includes an adjustment seat 6011 mounted on the body 501 of the liquid sample detection device 5, a first power component 6012 disposed on the adjustment seat 6011, and an adjustment bracket 6013. The first power component 6012 can drive the adjustment bracket 6013 to rotate. The adjustment bracket 6013 is used to assemble with the sampling element to adjust the rotation angle of the sampling element relative to the body 501 of the liquid sample detection device 5.
[0727] The second adjustment component 602 includes a second power component 6021 mounted on the adjustment bracket 6013 and a movable bracket 6022 connected to the second power component 6021. The second power component 6021 can drive the movable bracket 6022 to move relative to the adjustment bracket 6013. When the main body 501 is docked with the reagent kit, the sampling element is nested on one side of the movable bracket 6022. The movable bracket 6022 is connected to the sleeve and can drive the sleeve to switch between a first position and a second position.
[0728] The first adjustment component 601 also includes a rotating component 6014 disposed between the adjustment seat 6011 and the adjustment bracket 6013. The rotating component 6014 is connected to the adjustment bracket 6013. The first power component 6012 can drive the rotating component 6014 to rotate, thereby driving the adjustment bracket 6013 to rotate.
[0729] The adjusting seat 6011 is provided with a rotating groove 6015, and the rotating component 6014 is at least partially accommodated in the rotating groove 6015 and can rotate relative to the rotating groove 6015; the rotating groove 6015 is provided with a shaft hole 6016, and the adjusting bracket is provided with a rotating shaft 6017, which passes through the rotating component 6014 and is inserted into the shaft hole 6016.
[0730] The first power component 6012 is located on the side of the adjusting seat 6011 away from the rotating component 6014, and the rotating shaft of the first power component 6012 passes through the adjusting seat 6011 and is connected to the rotating component 6014 in a transmission manner.
[0731] The bottom wall of the rotating groove 6015 is provided with an arc-shaped groove 6015a extending along the rotation direction of the rotating member 6014. A first positioning member 6015b is provided on the arc-shaped groove 6015a, and a slider 6014a that can slide along the arc-shaped groove 6015a is provided on the rotating member 6014. The slider 6014a cooperates with the first positioning member 6015b to obtain the rotation angle of the rotating member 6014 relative to the adjusting seat 6011.
[0732] The adjusting bracket 6013 is assembled with the second adjusting component 602 so that when the first power component 6012 drives the adjusting bracket 6013 to rotate, the second adjusting component 602 can rotate synchronously with the adjusting bracket 6013.
[0733] The second adjustment component 602 includes a second power component 6021 mounted on the adjustment bracket 6013 and a movable bracket 6022 connected to the second power component 6021. The second power component 6021 can drive the movable bracket 6022 to move relative to the adjustment bracket 6013. When the liquid sample detection device is docked with the reagent kit, the sampling element is nested on one side of the movable bracket 6022. The movable bracket 6022 is connected to the sleeve of the sampling element and can drive the sleeve to switch between a first position and a second position.
[0734] The movable support 6022 includes a first movable support 6023 and a second movable support 6024. The first movable support 6023 is connected to the second power component 6021, and the second movable support 6024 is elastically connected to the first movable support 6023. When the liquid sample detection device is docked with the reagent kit, the second movable support 6024 is connected to the sleeve.
[0735] The adjustment device provided in this application embodiment adjusts the rotation angle of the sampling element through the first adjustment component and adjusts the axial position of the sleeve sleeved on the sampling element through the second adjustment component, so that the sampling element can switch between the first fluid path and the second fluid path, thereby enriching the sampling posture of the sampling element.
[0736] Please see Figure 7 and Figure 8 , Figure 7 This is a structurally disassembled schematic diagram of the biological tissue detection device 7 in some embodiments of this application. Figure 8 yes Figure 7 A schematic diagram of the structural breakdown of the biological tissue detection framework 8 in the embodiment.
[0737] The biological tissue detection device 7 generally includes a biological tissue detection frame 8, a biological tissue measurement platform 701, and auxiliary consumables 702. The biological tissue detection frame 8 has a cavity 801 and a first mounting position 802; the biological tissue measurement platform 701 is detachably mounted on the first mounting position 802 and has a first conduit; the auxiliary consumables 702 can be moved into or out of the cavity 801 and has a second conduit; a clearance channel 803 is provided between the cavity 801 and the first mounting position 802 to avoid mechanical docking operations between the biological tissue measurement platform 701 and the auxiliary consumables 702 and the consumable delivery path, the consumable delivery path being a passage connecting the first and second conduits.
[0738] The biological tissue detection frame 8 includes several plates that are connected to each other to form a cavity 801 and a first mounting position 802. The first mounting position 802 is used to install the biological tissue measurement platform 701, and the cavity 801 is used to contain the auxiliary consumables 702.
[0739] The plate includes a top plate 8011 and a bottom plate 8012 arranged opposite to each other, a cavity 801 is formed between the top plate 8011 and the bottom plate 8012, an avoidance channel 803 passes through the top plate 8011, and a first mounting position 802 is located on the side of the top plate 8011 away from the bottom plate 8012.
[0740] The cavity 801 has a pick-and-place port 8013, and the auxiliary consumable 702 can be moved into or out of the cavity 801 through the pick-and-place port 8013. The top plate 8011 is provided with a limiting member 8014 on the side opposite to the bottom plate 8012. The limiting member 8014 spans the clearance channel 803. The clearance channel 803 is used to limit the height of the auxiliary consumable 702 protruding from the top plate 8011 through the clearance channel 803.
[0741] The plate includes a top plate 8011 and a bottom plate 8012 arranged opposite to each other, and a side plate 8015 disposed between the top plate 8011 and the bottom plate 8012. The top plate 8011, the bottom plate 8012 and the side plate 8015 surround to form a cavity 801 with a pick-up and put-out opening 8013. The auxiliary consumable 702 can be moved into or out of the cavity 801 through the pick-up and put-out opening 8013. The clearance channel 803 passes through the top plate 8011. The first mounting position 802 is located on the side of the top plate 8011 away from the bottom plate 8012.
[0742] The side plate 8015 is opposite to the pick-and-place port 8013. The side plate 8015 has a first pair of interfaces 8015a and a second mounting position 8015b. The first pair of interfaces 8015a communicates with the cavity 801, and the second mounting position 8015b is used to install the adjustment device 703. When the auxiliary consumable 702 is moved into the cavity 801, the sampling element on the auxiliary consumable 702 is exposed through the first pair of interfaces 8015a to dock with the adjustment device 703.
[0743] Among them, the auxiliary consumable 702 has a sampling element 7021, and the biological tissue detection device 7 has an adjustment device 703. The adjustment device 703 is used to adjust the sampling posture of the sampling element 7021. When the auxiliary consumable 702 is moved into the cavity 801, the sampling element 7021 docks with the adjustment device 703.
[0744] The side plate 8015 has a second pair of interfaces 8015c and a third mounting position 8015d. The second pair of interfaces 8015c communicates with the cavity 801, and the third mounting position 8015d is used to install the valve device 704. When the auxiliary consumable 702 is moved into the cavity 801, the liquid bag connector inside the auxiliary consumable 702 is exposed through the second pair of interfaces 8015c to dock with the valve device 704.
[0745] The auxiliary consumable 702 has a receiving cavity for holding a liquid bag, and the cavity wall is provided with a liquid bag connector. The biological tissue detection device 7 has a valve device 704, which is used to connect with the liquid bag connector to control the liquid outflow from the liquid bag. When the auxiliary consumable 702 is moved into the cavity 801, the liquid bag connector connects with the valve device 704.
[0746] The side plate 8015 has a third pair of interfaces 8015e and a fourth mounting position 8015f. The third pair of interfaces 8015e connects to the cavity 801, and the fourth mounting position 8015f is used to install the drive device 705. When the auxiliary consumable 702 is moved into the cavity 801, the drive device 705 extends into the cavity 801 from the third pair of interfaces 8015e and docks with the auxiliary consumable 702 to drive the flow of liquid in the auxiliary consumable 702.
[0747] The auxiliary consumable 702 has a receiving cavity for holding the liquid bag, and the cavity wall is provided with a first driving member. The biological tissue detection device 7 has a driving device 705, which is used to dock with the first driving member to drive the liquid in the liquid bag to flow out. When the auxiliary consumable 702 is moved into the cavity 801, the driving device 705 docks with the first driving member.
[0748] The clearance passage 803 passes through the first mounting position 802, and the first mounting position 802 is provided with a positioning component 804, which is used to position the biological tissue measurement platform 701 on the top plate 8011.
[0749] The biological tissue detection framework provided in this application embodiment enables mechanical docking and consumable delivery between the auxiliary consumables in the cavity and the biological tissue measurement platform on the first mounting position by setting an obstacle avoidance channel between the cavity and the first mounting position. The structure is simple.
[0750] Please see Figure 9 , Figure 9 This is a structurally exploded schematic diagram of the sample analysis device 9 in some embodiments of this application. The sample analysis device 9 generally includes a fixed base 901, a mounting base 902, a conveying component 903, and a testing component 904. A guide rod 905 is provided between the fixed base 901 and the mounting base 902. The conveying component 903 is disposed between the fixed base 901 and the mounting base 902, and is sleeved on the guide rod 905, allowing it to slide along the guide rod 905. The testing component 904 is disposed between the fixed base 901 and the mounting base 902, and is sleeved on the guide rod 905, allowing it to slide along the guide rod 905.
[0751] The test component 904 is located on the side of the conveying component 903 away from the fixed seat 901. A first elastic element 906 is provided between the conveying component 903 and the fixed seat 901 so that the conveying component 903 and the fixed seat 901 can be separated by the first elastic element 906.
[0752] See also Figure 10 , Figure 10 yes Figure 9 The conveying component 903 in the embodiment is shown in the structural exploded view. The conveying component 903 generally includes a support seat 9031 sleeved on the guide rod 905 and slidable along the guide rod 905, a telescopic seat 9032 slidably connected to the support seat 9031, a first driving member 9033 disposed on the support seat 9031, a first elastic member 906 disposed between the support seat 9031 and the fixed seat 901, and the first driving member 9033 can drive the telescopic seat 9032 to move relative to the support seat 9031.
[0753] The support seat 9031 is provided with a channel 9031a that passes through the support seat 9031 along the moving direction of the telescopic seat 9032. The telescopic seat 9032 is partially located in the channel 9031a and can move relative to the support seat 9031 along the channel 9031a.
[0754] The telescopic base 9032 is provided with a slot 9032a for placing the detection component. When the telescopic base 9032 moves relative to the support base 9031, the slot 9032a can switch between a first position and a second position. When the slot 9032a is in the first position, the detection component can be moved into or out of the slot 9032a. When the slot 9032a is in the second position, the slot 9032a is received in the channel 9031a.
[0755] The support 9031 includes a top wall 9031b and a bottom wall 9031c disposed opposite to each other. The bottom wall 9031c is located on the side of the support 9031 near the fixed base 901, and the top wall 9031b is located on the side of the support 9031 near the test component 904. A channel 9031a is formed between the top wall 9031b and the bottom wall 9031c. The top wall 9031b is provided with a first clearance hole 9031d, and the bottom wall 9031c is provided with a second clearance hole 9031e. When the slot 9032a is in the second position, the detection element of the detection component placed in the slot 9032a is exposed to the first clearance hole 9031d, and the test component 904 can dock with the detection element of the detection component through the first clearance hole 9031d. The liquid hole of the detection component is exposed to the second clearance hole 9031e.
[0756] The telescopic seat 9032 is provided with a transmission component 9032b, which is assembled with the first driving component 9033 so that the telescopic seat 9032 can be moved by the transmission component 9032b under the drive of the first driving component 9033.
[0757] The telescopic seat 9032 is provided with a clearance groove 9032c, the transmission component 9032b is provided on the groove wall of the clearance groove 9032c, and the output shaft of the first driving component 9033 extends into the clearance groove 9032c and is connected to the transmission component 9032b for transmission.
[0758] See also Figure 11 , Figure 11 yes Figure 9 The schematic diagram of the structure of the test component 904 in the embodiment shows that a second elastic member 907 is provided between the transport component 903 and the test component 904 so that the transport component 903 and the test component 904 can be separated by the second elastic member 907.
[0759] The test assembly 904 includes a test seat 9041 sleeved on the guide rod 905 and slidable along the guide rod 905, and a test plate 9042 disposed on the test seat 9041. The test plate 9042 is provided with a test head 9043. When the test seat 9041 and the support seat 9031 are docked, the test head 9043 contacts the detection element of the detection assembly through the first clearance hole 9031d.
[0760] The test assembly 904 also includes a support assembly 9044 disposed on the test seat 9041, and a second elastic member 907 disposed between the support assembly 9044 and the test seat 9041. When the test seat 9041 and the support seat 9031 are docked so that the test plate 9042 contacts the detection element of the detection assembly, the second elastic member 907 is compressed to generate elastic force, which enables the support assembly 9044 and the test seat 9041 to separate.
[0761] The test base 9041 has a first mounting position 9041a and a second mounting position 9041b on the same side. The test plate 9042 is mounted at the first mounting position 9041a, and the supporting component 9044 is mounted at the second mounting position 9041b. Before the second elastic member 907 is compressed, the height of the supporting component 9044 protruding from the test base 9041 is not less than the height of the test head 9043 protruding from the test base 9041.
[0762] The mounting base 902 is provided with a second driving component 9021, which is used to drive the test base 9041 to slide along the guide rod 905.
[0763] The test seat 9041 is provided with a first positioning component on the side near the support seat 9031, and the support seat 9031 is provided with a second positioning component on the side near the test seat 9041. During the docking process of the test seat 9041 and the support seat 9031, the first positioning component and the second positioning component cooperate to guide the docking of the test seat 9041 and the support seat 9031.
[0764] See also Figure 12 , Figure 12 yes Figure 11 A schematic diagram showing the disassembled structure of the supporting component 9044 in the embodiment. The supporting component 9044 includes a body 9044a and a limiting member 9044b. The limiting member 9044b is fixed to the second mounting position 9041b, and a second elastic member 907 is disposed between the body 9044a and the second mounting position 9041b. The body 9044a and the limiting member 9044b are slidably connected, and the limiting member 9044b is used to limit the sliding stroke of the body 9044a under the action of elastic force.
[0765] The sample analysis device provided in this application embodiment enables the conveying component and the fixed base to be separated by a first elastic element. , Furthermore, by setting a second elastic element, the conveying component and the testing component can be separated through the second elastic element. That is, when the sample analysis device completes the analysis operation, there is no need to set up other driving mechanisms. The separation of the conveying component and the fixed seat, as well as the separation of the conveying component and the testing component, can be achieved through the first elastic element and the second elastic element. The overall structure is simple.
[0766] Please see Figures 13 to 15 , Figure 13 This is a structurally exploded schematic diagram of the biological detection device 13 in some embodiments of this application. Figure 14 yes Figure 13 A partial structural schematic diagram of the biological detection device 13 in the embodiment. Figure 15 yes Figure 13 A partial structural schematic diagram of the biological detection device 13 in the embodiment.
[0767] The biological detection device 13 generally includes a first base 1301, a second base 1302, a guide 1303, a testing component 1304, and a transmission component 1305. The guide 1303 is located between the first base 1301 and the second base 1302 and extends in the arrangement direction of the first base 1301 and the second base 1302; the testing component 1304 is disposed on the guide 1303 and is movable along the guide 1303; the transmission component 1305 is mounted on the first base 1301 and includes a drive component 1305a.
[0768] Among them, the test component 1304 is provided with a top support 1304a on the side near the first base 1301, and the driving component 1305a and the top support 1304a roll together to drive the test component 1304 to move along the guide 1303.
[0769] The transmission assembly 1305 includes a power component 1305b mounted on the first base 1301 and a support shaft 1305c passing through the drive component 1305a. The power component 1305b and the support shaft 1305c are connected in a transmission assembly to drive the support shaft 1305c to rotate, and the rotation of the support shaft 1305c causes the drive component 1305a to rotate synchronously.
[0770] The biological detection device 13 also includes an assembly bracket 1301a and a drive bracket 1301b spaced apart on the first base 1301, a support shaft 1305c located between the assembly bracket 1301a and the drive bracket 1301b, and a power component 1305b mounted on the drive bracket 1301b.
[0771] The first base 1301 is provided with a clearance hole 1301c, which is used to avoid the drive member 1305a. The mounting bracket 1301a is provided on the side of the first base 1301 near the test component 1304. At least one of the first base 1301 and the test component 1304 is provided with a separator 1301d, which is provided between the first base 1301 and the test component 1304 to avoid the mounting bracket 1301a interfering with the rolling engagement between the drive member 1305a and the top member 1304a.
[0772] The assembly bracket 1301a includes a first bracket 1301e and a second bracket 1301f spaced apart. The second bracket 1301f is located between the first bracket 1301e and the drive bracket 1301b, and the support shaft 1305c is located between the first bracket 1301e and the drive bracket 1301b. The drive component 1305a is located between the first bracket 1301e and the second bracket 1301f and is correspondingly arranged with the clearance hole 1301c. The power component 1305b and the support shaft 1305c are connected for transmission between the second bracket 1301f and the drive bracket 1301b.
[0773] The first bracket 1301e is provided with a first positioning element 1301g, and the driving element 1305a or the support shaft 1305c is provided with a second positioning element 1301h. The second positioning element 1301h rotates synchronously with the driving element 1305a or the support shaft 1305c and cooperates with the first positioning element 1301g to obtain the rotation angle of the driving element 1305a or the support shaft 1305c.
[0774] The power component 1305b is located on the side of the drive bracket 1301b away from the second bracket 1301f, and the output shaft of the power component 1305b passes through the drive bracket 1301b and is connected to the support shaft 1305c for transmission.
[0775] The transmission assembly 1305 includes a first transmission assembly 1305d disposed between the drive bracket 1301b and the second bracket 1301f. The output shaft of the power component 1305b passes through the drive bracket 1301b and extends into the space between the drive bracket 1301b and the second bracket 1301f, and is provided with a first transmission wheel 1305e. The support shaft 1305c is provided with a second transmission wheel 1305f in the portion located between the drive bracket 1301b and the second bracket 1301f. The first transmission assembly 1305d is respectively connected to the first transmission wheel 1305e and the second transmission wheel 1305f for transmission.
[0776] The first transmission assembly 1305d includes a first fixed shaft 1305g disposed between the drive bracket 1301b and the second bracket 1301f, a first driving wheel 1305h and a first driven wheel 1305i disposed on the first fixed shaft 1305g; the first driving wheel 1305h is drivenly assembled with the first transmission wheel 1305e, and the first driven wheel 1305i is drivenly assembled with the second transmission wheel 1305f.
[0777] Among them, the diameter of the first driving wheel 1305h is larger than the diameter of the first driven wheel 1305i, the axial thickness of the first driving wheel 1305h is smaller than the axial thickness of the first transmission wheel 1305e, the diameter of the first driven wheel 1305i is smaller than the diameter of the second transmission wheel 1305f, and the axial thickness of the second transmission wheel 1305f is smaller than the axial thickness of the first driven wheel 1305i.
[0778] The transmission assembly 1305 includes a second transmission assembly 1305j disposed between the first transmission assembly 1305d and the second transmission wheel 1305f, and the second transmission assembly 1305j is respectively connected to the first transmission assembly 1305d and the second transmission wheel 1305f for transmission.
[0779] The second transmission assembly 1305j includes a second fixed shaft 1305k disposed between the drive bracket 1301b and the second bracket 1301f, a second driving wheel 1305m and a second driven wheel 1305n disposed on the second fixed shaft 1305k; the second driving wheel 1305m is drivenly assembled with the first driven wheel 1305i, and the second driven wheel 1305n is drivenly assembled with the second transmission wheel 1305f.
[0780] Among them, the diameter of the second driving wheel 1305m is larger than the diameter of the second driven wheel 1305n, the axial thickness of the second driving wheel 1305m is smaller than the axial thickness of the first driven wheel 1305i, the diameter of the second driven wheel 1305n is smaller than the diameter of the second transmission wheel 1305f, and the axial thickness of the second transmission wheel 1305f is smaller than the axial thickness of the second driven wheel 1305n.
[0781] The first bracket 1301e and the test component 1304 are provided with a limiting block 1301k and a limiting groove 1304b, respectively. The limiting block 1301k and the limiting groove 1304b cooperate to limit the distance between the first base 1301 and the test component 1304.
[0782] Among them, the driving component 1305a can be a turbine, and the top support component 1304a can be a roller.
[0783] The biological detection device provided in this application embodiment can ensure the stability of the movement of the test component by setting a top support and a driving component in a rolling cooperation on the detection component to drive the test component to move along the guide rod, and can move the test component to a preset position for corresponding testing.
[0784] Please see Figures 16 to 18 , Figure 16 This is a structural breakdown diagram of the blood sample analysis platform 16 in some embodiments of this application. Figure 17 yes Figure 16 A partial structural schematic diagram of the blood sample analysis platform 16 in this embodiment. Figure 18 yes Figure 16 A partial structural diagram of the blood sample analysis platform 16 in the embodiment.
[0785] The blood sample analysis platform 16 generally includes a blood sample analyzer 1601 and an auxiliary liquid container 1602. The blood sample analyzer 1601 has a non-contact detection element 1601a and a clearance groove 1601b. The auxiliary liquid container 1602 has a cavity 1602a and a liquid path 1602b. The cavity 1602a is used to hold the auxiliary liquid 1602c and the waste liquid bag 1602d. One end of the liquid path 1602b is used to input the auxiliary liquid 1602c, and the other end is used to connect to the waste liquid bag 1602d.
[0786] The liquid path 1602b has a portion exposed outside the auxiliary liquid box 1602, and the non-contact detection element 1601a is used to detect the portion entering the clearance groove 1601b.
[0787] The blood sample analysis platform 16 includes a mounting bracket 1603, which has a receiving cavity 1603a and a first mounting position 1603b. An auxiliary liquid box 1602 can be moved into or out of the receiving cavity 1603a. The first mounting position 1603b is used to mount the blood sample analyzer 1601. The receiving cavity 1603a and the first mounting position 1603b are provided with a clearance channel. When the auxiliary liquid box 1602 is moved into the receiving cavity, the part of the liquid path 1602b exposed outside the auxiliary liquid box 1602 enters the clearance groove 1601b through the clearance channel.
[0788] The auxiliary liquid box 1602 is provided with a sample inlet seat 1602e, and the liquid path 1602b includes a liquid channel 1602f disposed in the sample inlet seat 1602e; wherein, when the auxiliary liquid box 1602 moves into the receiving cavity 1603a, the sample inlet seat 1602e moves into the clearance groove 1601b, so that the non-contact detection element 1601a can detect the liquid in the liquid channel 1602f.
[0789] The liquid channel 1602f includes an inlet section 1602g, an outlet section 1602h, and a detection section 1602i connecting the inlet section 1602g and the outlet section 1602h. The inlet section 1602g is used to input auxiliary liquid 1602c, and the outlet section 1602h is used to connect to the waste liquid bag 1602d. When the sample inlet seat 1602e moves into the clearance groove 1601b, the non-contact detection element 1601a can detect the liquid in the detection section 1602i.
[0790] The sample inlet 1602e is provided with a light-transmitting area 1602j corresponding to the detection section 1602i, so that the light emitted by the blood sample analyzer 1601 can irradiate the liquid in the detection section 1602i through the light-transmitting area 1602j for detection.
[0791] The blood sample analyzer 1601 includes a test base 1601c and a test plate 1601d. The test base 1601c is mounted on a first mounting position 1603b, and the test plate 1601d is mounted on the test base 1601c. A clearance groove 1601b is formed on the test base 1601c, and a non-contact detection element 1601a is connected to the test base 1601c for detecting liquid entering the clearance groove 1601b. The non-contact detection element 1601a includes a light source and a photosensitive device disposed on the test plate 1601d. The light emitted by the light source can pass through the light-transmitting area 1602j to reach the photosensitive device and thus detect the liquid in the detection section 1602i.
[0792] The blood sample analyzer 1601 includes an ultrasonic transmitter, which is mounted on the test base 1601c to perform ultrasonic treatment on the liquid in the liquid channel 1602f that enters the clearance tank 1601b.
[0793] The test socket 1601c is used to dock with or separate from the auxiliary liquid box 1602. The liquid path of the auxiliary liquid box 1602 has a curved portion that protrudes from the auxiliary liquid box 1602. When the test socket 1601c and the auxiliary liquid box 1602 dock, the portion enters the clearance groove 1601b to be detected by the non-contact detection element 1601a.
[0794] The fluid path of the auxiliary fluid cartridge 1602 has a portion exposed outside the auxiliary fluid cartridge 1602. This portion enters the clearance groove of the blood sample analyzer 1601 when the auxiliary fluid cartridge 1602 is docked with the blood sample analyzer 1601, so that it can be detected by the non-contact detection element of the blood sample analyzer 1601.
[0795] The blood sample analysis platform provided in this application exposes the liquid path portion of the auxiliary liquid box outside the auxiliary liquid box, and when this portion enters the clearance slot of the blood sample analyzer, the non-contact detection element of the blood sample analyzer can detect this portion, thereby realizing non-contact detection of liquid in the liquid path.
[0796] Please see Figures 19 to 21 , Figure 19 This is a structurally exploded schematic diagram of the fluid detection instrument 19 in some embodiments of this application. Figure 20 yes Figure 19 A partial structural schematic diagram of the fluid detection instrument 19 in the embodiment. Figure 21 yes Figure 19 A partial structural schematic diagram of the fluid detection instrument 19 in the embodiment.
[0797] The fluid detection instrument 19 generally includes a valve assembly 1901 and a fluid box 1902. The valve assembly 1901 has a control element 1901a, a first pipe 1901b, an inlet 1901c, and an outlet 1901d. There are several inlets 1901c. The control element 1901a is used to control one of the inlets 1901c to be connected to one end of the first pipe 1901b. The other end of the first pipe 1901b is connected to the outlet 1901d.
[0798] The fluid box 1902 has a cavity 1902a and an interface 1902b. The cavity 1902a is used to place the fluid pack, and one end of the interface 1902b is used to connect to the fluid pack, and the other end is used to connect to the inlet 1901c.
[0799] The valve assembly 1901 and the fluid box 1902 can be connected or separated, so that the inlet 1901c and the interface 1902c can be connected or separated. When connected, the first pipe 1901b can be connected to the interface 1902c under the control of the control element 1901a, so that the fluid in the fluid box can reach the first pipe 1901b.
[0800] The valve assembly 1901 has an air hole 1901e, and one end of the first pipe 1901b is selectively connected to the inlet 1901c or the air hole 1901e under the control of the control element 1901a.
[0801] The fluid box 1902 is provided with a docking groove 1902c, which is used to dock with the sampling element 1902d. The docking groove 1902c is provided with a through hole 1902e and a connecting pipe 1902f passing through the through hole 1902e. One end of the connecting pipe 1902f is connected to the outlet 1901d, and the other end is used to connect to the sampling end of the sampling element 1902d. The connecting pipe 1902f is in sealed contact with the hole wall of the through hole 1902e.
[0802] The sampling element 1902d includes a sampling needle 1902g, a sleeve 1902h sleeved on the sampling needle 1902g, and a docking member 1902i at the end of the sleeve 1902h. The outer diameter of the sleeve 1902h does not exceed the inner diameter of the docking groove 1902c. The docking member 1902i has a through hole 1902j. The docking member 1902i can move along the axial direction of the sampling needle 1902g with the sleeve 1902h so that the sampling needle 1902g is inserted into one end of the through hole 1902j or passes through the through hole 1902j and is exposed on one side of the docking member 1902i.
[0803] When the sleeve 1902h moves along the axial direction of the sampling needle 1902g and toward the connecting tube 1902f so that the docking piece 1902i is inserted into the docking groove 1902c, the sampling needle 1902g and the connecting tube 1902f are respectively inserted into the two ends of the through hole 1902j to achieve communication.
[0804] The valve assembly 1901 includes a control element 1901a, a first pipe 1901b, an inlet 1901c, and an outlet 1901d. The number of inlets 1901c is plurality of, and the control element 1901a controls one of the inlets 1901c to connect to one end of the first pipe 1901b, the other end of the first pipe 1901b connecting to the outlet 1901d. The inlets 1901c are used to connect or disconnect from the interface of the fluid box 1902, so that when connected, the control element 1901a controls the inlet 1901c to obtain fluid from the fluid box 1902.
[0805] The fluid box 1902 includes a cavity 1902a and an interface 1902b. The cavity 1902a is used to hold a fluid pack. One end of the interface 1902b is connected to the fluid pack, and the other end is connected to an inlet 1901c and an inlet of the valve assembly 1901. The valve assembly 1901 and the fluid box 1902 can be docked or detached, so that when docked, fluid in the fluid box 1902 can be transferred to the valve assembly 1901 through the interface 1902b.
[0806] The fluid detection instrument provided in this application embodiment allows for the docking or disassembly of the valve assembly and fluid housing, enabling detachable assembly and disassembly of the fluid housing and valve assembly. During docking, the control element of the valve assembly controls the interface between the first pipe of the valve assembly and the fluid housing, allowing the liquid in the fluid housing to reach the first pipe for detection. Furthermore, the control element can control one of several inlets to connect to the first pipe, facilitating the selection of the liquid flowing into the first pipe.
[0807] Please see Figure 22 , Figure 22 This is a schematic diagram of the integrated reagent kit 22 in some embodiments of this application. The integrated reagent kit 22 generally includes a housing 2201, a sampling device 2202, a first conduit 2203, and a second conduit 2204. The housing 2201 has a receiving space 2201a for storing reagent packs and a return pack. The sampling device 2202 is disposed on the housing 2201 and located outside the receiving space 2201a. The first conduit 2203 and the second conduit 2204 are disposed on the housing 2201. The input end of the sampling device 2202 is connected to the reagent pack through the first conduit 2203, and the output end of the sampling device 2202 is connected to the return pack through the second conduit 2204. The sampling device 2202 is rotatable relative to the housing 2201 so that the input end of the sampling device 2202 can collect liquid from the reagent pack or an external container.
[0808] The housing 2201 has a first interface 2201b and a second interface 2201c spaced apart. The first interface 2201b is connected to the output end of the sampling device 2202, and the second interface 2201c is connected to the recovery pack via a second pipe 2204. The first interface 2201b and the second interface 2201c are used to interface with the detection component so that the liquid collected by the sampling device 2202 can reach the detection component.
[0809] The housing 2201 has a sample inlet 2201d located outside the housing space 2201a. A first interface 2201b and a second interface 2201c are located on the sample inlet 2201d. The sample inlet 2201d has a first connecting tube 2201e and a second connecting tube 2201f. One end of the first connecting tube 2201e is connected to the first interface 2201b and the other end is connected to the output end of the sampling device 2202. One end of the second connecting tube 2201f is connected to the second interface 2201c and the other end is used to connect to the recovery pack.
[0810] The output end of the sampling device 2202 is inserted into the sample inlet 2201d and connected to the first connecting tube 2201e.
[0811] The sample inlet 2201d includes a seat body 2201g and a tube body 2201h located at the end of the seat body 2201g. A first interface 2201b and a second interface 2201c are located on the seat body 2201g. One end of the first connecting tube 2201e is inserted into the tube body 2201h and the other end is connected to the first interface 2201b. The output end of the sampling device 2202 is inserted into the tube body 2201h to communicate with the first connecting tube 2201e.
[0812] The sampling device 2202 includes a sampling element 2202a, a sleeve 2202b fitted onto the input end of the sampling element 2202a, and a buckle 2202c fitted onto the output end of the sampling element 2202a. The buckle 2202c is rotatably assembled with the tube body 2201h so that the buckle 2202c can rotate relative to the tube body 2201h. The rotation of the buckle 2202c can drive the sleeve 2202b to rotate so that the input end of the sampling element 2202a can collect liquid from the reagent package or external container.
[0813] The tube body 2201h has a first hole section 2201j and a second hole section 2201k that are connected to each other. The first hole section 2201j is used to rotatably connect with the buckle 2202c. The output end of the sampling element 2202a and the first connecting tube 2201e are connected through the second hole section 2201k. The diameter of the first hole section 2201j is larger than the diameter of the second hole section 2201k.
[0814] Among them, the rotating buckle 2202c includes a first rotating buckle 2202d and a second rotating buckle 2202e clamped in the sleeve 2202b. The first rotating buckle 2202d is rotatably assembled with the tube body 2201h, and the second rotating buckle 2202e can rotate relative to the tube body 2201h under the action of external force, thereby driving the sleeve 2202b to rotate.
[0815] The sleeve 2202b can move axially along the sampling end of the sampling element 2202a under the action of external force, so as to expose or cover the sampling end of the sampling element 2202a; the sleeve 2202b is provided with a clearance hole to avoid the sampling element 2202a when the sleeve 2202b moves axially.
[0816] The box 2201 is provided with a docking seat 2201m, which has an interface 2201n. The interface 2201n is used to dock with the input end of the sampling device 2202. One end of the first pipe 2203 is connected to the interface 2201n, and the other end is used to connect to the reagent pack.
[0817] The integrated reagent kit provided in this application embodiment, through a sampling device, a first pipe, and a second pipe set on the box body, enables the sampling device to collect liquid from the reagent pack through the first pipe, and the liquid from the sampling device to reach the recovery pack through the second pipe; in addition, by setting the sampling device to be rotatable relative to the box body, the sampling device can collect liquid from external containers or reagent packs, improving the diversity of liquids collected by the sampling device and the flexibility of the reagent kit.
[0818] Please see Figure 23 and 24 , Figure 23 This is a partial structural schematic diagram of the reagent storage device 23 in some embodiments of this application. Figure 24 yes Figure 23 A schematic diagram of the cross-sectional structure of the reagent storage device 23 in the embodiment.
[0819] The reagent storage device 23 generally includes a storage box 2301, a sampling component 2302 disposed on the storage box 2301 and located outside the storage box 2301, and a docking component 2303. The outlet end of the sampling component 2302 is connected to a first position inside the storage box 2301, and the docking component 2303 has a sampling groove 2303a connected to a second position inside the storage box 2301. The sampling component 2302 and the docking component 2303 can be connected or separated. When the sampling component 2302 and the docking component 2303 are connected, the inlet end of the sampling component 2302 is inserted into the sampling groove 2303a to take a sample from the second position inside the storage box 2301. When the sampling component 2302 and the docking component 2303 are separated, the inlet end of the sampling component 2302 can take a sample from outside the storage box 2301.
[0820] The docking component 2303 includes a docking seat 2303b mounted on the storage box 2301, a sampling slot 2303a formed on the docking seat 2303b, and a connector tube 2303c provided inside the sampling slot 2303a. One end of the connector tube 2303c is used to connect to the inlet end of the sampling component 2302, and the other end is used to connect to a second position inside the storage box 2301. The inlet end of the sampling component 2302 is provided with a connector 2302a. When the sampling component 2302 and the docking component 2303 are connected, the connector tube 2303c is inserted into the conn...
Claims
1. A biological sample analysis device, characterized in that, include: Drive component, with output shaft; A reagent storage device includes a storage cavity, a connecting pipe, and a squeezing assembly. The storage cavity is used to hold reagent packs and recycling packs. The connecting pipe is partially embedded in the squeezing assembly. One end of the connecting pipe is used to connect to the reagent pack, and the other end is used to connect to the recycling pack. The drive assembly and the reagent storage device can be docked or separated, so that the output shaft can be docked or separated from the extrusion assembly; when docked, the output shaft can drive the extrusion assembly to extrude the connecting pipe so that the liquid in the connecting pipe can flow.
2. The biological sample analysis device according to claim 1, characterized in that, The extrusion assembly includes a first extruder and a second extruder, the second extruder being embedded in the first extruder and coaxially arranged with the first extruder, and the connecting pipe portion being disposed between the first extruder and the second extruder; wherein, the second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the connecting pipe.
3. The biological sample analysis device according to claim 2, characterized in that, The first extrusion member is annular, and the second extrusion member has a rotating part and an extrusion part. The rotating part is used to dock with the output shaft, and the extrusion part is located on the periphery of the rotating part and can rotate synchronously with the rotating part. The extrusion section is spaced apart from the first extrusion member, and the connecting pipe section is located between the extrusion section and the first extrusion member.
4. The biological sample analysis device according to claim 3, characterized in that, The rotating part has a shaft hole, one end of the output shaft is assembled with the shaft hole, and a bushing is fitted on the extrusion part for abutting the connecting pipe.
5. The biological sample analysis device according to any one of claims 1 to 4, characterized in that, The biological sample analysis device further includes a mounting bracket, which has a cavity and a first mounting position. The reagent storage device can be moved into or out of the cavity, and the drive assembly is mounted on the first mounting position. The first mounting position is located at the end of the travel distance when the reagent storage device moves into the cavity.
6. The biological sample analysis device according to claim 5, characterized in that, The drive assembly is located outside the cavity, and there is a clearance hole between the cavity and the first mounting position. The output shaft of the drive assembly extends into the cavity through the clearance hole. When the reagent storage device is moved into the cavity, the output shaft of the drive assembly is driven and assembled with the extrusion assembly.
7. The biological sample analysis device according to any one of claims 1 to 4, characterized in that, The cavity wall of the storage chamber is provided with a storage groove, the extrusion assembly is embedded in the storage groove and coaxially arranged with the storage groove, and the connecting pipe is located between the storage groove and the extrusion assembly; wherein, the extrusion assembly is used for drive assembly with the output shaft, so as to rotate relative to the storage groove under the drive of the output shaft and thereby extrude the connecting pipe.
8. The biological sample analysis device according to claim 1, characterized in that, The biological sample analysis device further includes a mounting bracket, which has a cavity and a first mounting position. The reagent storage device can be moved into or out of the cavity, and the drive assembly is mounted on the first mounting position. The first mounting position is located at the end of the travel distance when the reagent storage device moves into the cavity. The drive assembly is located outside the cavity, and there is a clearance hole between the cavity and the first mounting position. The output shaft of the drive assembly extends into the cavity through the clearance hole. When the reagent storage device is moved into the cavity, the output shaft of the drive assembly is driven and assembled with the extrusion assembly. The extrusion assembly includes a first extruder and a second extruder. The second extruder is embedded in the first extruder and coaxially arranged with the first extruder. The connecting pipe portion is located between the first extruder and the second extruder. The second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the connecting pipe. The first extrusion member is annular, and the second extrusion member has a rotating part and an extrusion part. The rotating part is used to dock with the output shaft, and the extrusion part is located on the periphery of the rotating part and can rotate synchronously with the rotating part. The extrusion section is spaced apart from the first extrusion member, and the connecting pipe section is located between the extrusion section and the first extrusion member; The rotating part has a shaft hole, one end of the output shaft is assembled with the shaft hole, and a bushing is fitted on the extrusion part for abutting the connecting pipe; The cavity wall of the storage chamber is provided with a storage groove, the extrusion assembly is embedded in the storage groove and coaxially arranged with the storage groove, and the connecting pipe is located between the storage groove and the extrusion assembly; wherein, the extrusion assembly is used for drive assembly with the output shaft, so as to rotate relative to the storage groove under the drive of the output shaft and thereby extrude the connecting pipe.
9. A reagent storage device, applied to a biological sample analysis device, the biological sample analysis device having a drive assembly with an output shaft, characterized in that, include: Storage cavity, connecting pipes, and extrusion assembly; The storage cavity is used to hold the reagent pack and the recycling pack, and the connecting pipe is embedded in the extrusion assembly; one end of the connecting pipe is used to connect the reagent pack and the other end is used to connect the recycling pack. The reagent storage device is used to dock with or separate from the drive assembly, so that the squeezing assembly docks with or separates from the output shaft; when docking, the squeezing assembly can be driven by the output shaft to squeeze the connecting pipe so that the liquid in the connecting pipe can flow.
10. The reagent storage device according to claim 9, characterized in that, The extrusion assembly includes a first extruder and a second extruder, the second extruder being embedded in the first extruder and coaxially arranged with the first extruder, and the connecting pipe portion being disposed between the first extruder and the second extruder; wherein, the second extruder is used for drive assembly with the output shaft to rotate relative to the first extruder under the drive of the output shaft, thereby extruding the connecting pipe.
11. The reagent storage device according to claim 10, characterized in that, The first extrusion member is annular, and the second extrusion member has a rotating part and an extrusion part. The rotating part is used to dock with the output shaft, and the extrusion part is located on the periphery of the rotating part and can rotate synchronously with the rotating part. The extrusion section is spaced apart from the first extrusion member, and the connecting pipe section is located between the extrusion section and the first extrusion member.
12. The reagent storage device according to claim 11, characterized in that, The rotating part has a shaft hole, and one end of the output shaft is assembled with the shaft hole; a bushing is fitted on the extrusion part, and the bushing is used to abut against the connecting pipe.
13. The reagent storage device according to any one of claims 9 to 12, characterized in that, The cavity wall of the storage chamber is provided with a storage groove, the extrusion assembly is embedded in the storage groove and coaxially arranged with the storage groove, and the connecting pipe is located between the storage groove and the extrusion assembly; wherein, the extrusion assembly is used for drive assembly with the output shaft, so as to rotate relative to the storage groove under the drive of the output shaft and thereby extrude the connecting pipe.