Temperature control device for microscope

By combining a graphene heating device and a sand bath device with a dual-channel electronic temperature controller, the problem of insufficient temperature control in traditional microscope stages is solved, achieving high-precision temperature control and convenient sample processing, making it suitable for biological laboratories and medical testing.

CN224366361UActive Publication Date: 2026-06-16HUAIAN BIOLOGICAL ENG HIGHER VOCATIONAL SCHOOL

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
HUAIAN BIOLOGICAL ENG HIGHER VOCATIONAL SCHOOL
Filing Date
2025-08-21
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

Traditional microscope stages lack temperature control functions, which cannot meet the requirements for constant temperature preservation of live samples. Furthermore, existing temperature control equipment is bulky and has low modularity, making it difficult to adapt to the diversity of biological samples.

Method used

The system employs a graphene heating device and a sand bath device combined with a dual-channel electronic temperature controller. The graphene heating device is used to maintain the temperature during microscopic observation, the sand bath device is used for sample preheating, and the dual-channel electronic temperature controller achieves precise temperature control.

🎯Benefits of technology

It provides a convenient constant temperature environment, is highly adaptable, has high temperature control accuracy, reduces equipment procurement costs and space occupation, and is suitable for biological laboratories and medical testing.

✦ Generated by Eureka AI based on patent content.

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    Figure CN224366361U_ABST
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Abstract

The utility model discloses a temperature control device for microscope, this temperature control device includes flaky graphene heating device, sand bath device and two -way electronic temperature controller, wherein, sand bath device is used for heating the sample and consumable before microscopic observation, and sand bath device is connected with two -way electronic temperature controller through circuit to accept the temperature control of two -way electronic temperature controller, graphene heating device is used for bearing object glass or petri dish and is used for keeping the sample temperature when microscope observation is relatively constant, graphene heating device is connected with two -way electronic temperature controller through circuit to accept the temperature control of two -way electronic temperature controller, two -way electronic temperature controller is used for controlling the heating temperature of graphene heating device and sand bath device, the temperature control device can be provided to the sample and consumable before microscopic observation to the sample and consumable before microscopic observation, and can guarantee the sample constant temperature preservation and observation environment when microscopic observation, has portable, modularization, accurate temperature control's characteristics, can adapt to multiple types sample.
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Description

Technical Field

[0001] This utility model relates to the field of biomedical equipment technology, specifically a temperature control device for microscopes suitable for scenarios such as constant temperature preservation and observation of biological samples. Background Technology

[0002] In biomedical research, microscope stages often need to provide a constant temperature for live samples to maintain their viability. However, traditional stages often lack temperature control, and standalone thermostatic stages are limited in function and cannot meet the requirements for temperature-controlled sample preservation before loading. Existing aluminum alloy metal baths can provide a heat source, but they are bulky and inconvenient to use, have low modularity, insufficient temperature control precision, and are difficult to accommodate the diversity of biological samples. Utility Model Content

[0003] The purpose of this invention is to overcome the shortcomings of existing equipment, such as limited functionality and poor adaptability, and to provide a temperature control device for microscopes that ensures a constant temperature environment before and after sample observation, is easy to use, highly adaptable, modular, and easy to maintain.

[0004] The objective of this utility model is achieved through the following technical solution:

[0005] A temperature control device for a microscope, characterized in that: the temperature control device includes a sheet-like graphene heating device, a sand bath device, and a dual-channel electronic temperature controller, wherein the sand bath device is used to heat the sample and consumables before microscopic observation, and the sand bath device is connected to the dual-channel electronic temperature controller via a circuit to receive temperature control from the dual-channel electronic temperature controller; the graphene heating device is used to support the slide or culture dish and to maintain a relatively constant sample temperature during microscopic observation, and the graphene heating device is connected to the dual-channel electronic temperature controller via a circuit to receive temperature control from the dual-channel electronic temperature controller; the dual-channel electronic temperature controller is used to control the heating temperature of the graphene heating device and the sand bath device.

[0006] The graphene heating device uses a cyclic graphene heating film for heating, and the sand bath device uses a polyimide flexible heating film for heating.

[0007] The aforementioned cyclic graphene heating film, with a light-transmitting hole in its center, can operate independently to provide a relatively stable observation temperature for microscopic observation of biological samples. The aforementioned flexible polyimide heating film, by constant-temperature heating of metal sand, can independently provide a pre-observation temperature bath for samples, slides, etc. Both the aforementioned cyclic graphene heating film and the aforementioned flexible polyimide heating film are characterized by adjustable temperature and wide applicability, effectively solving the problems of traditional equipment's limited functionality, high cost of temperature control equipment, and low modularity.

[0008] The graphene heating device includes an annular graphene heating film and a first temperature sensor, which are electrically connected to a dual-channel electronic temperature controller via circuits. The annular graphene heating film has a light-transmitting hole in the middle that matches the microscope stage. The first temperature sensor is used to monitor the heating temperature of the annular graphene heating film and provide real-time feedback to the dual-channel electronic temperature controller.

[0009] The upper surface of the cyclic graphene heating film is covered with a thermally conductive insulating film, and the lower surface is covered with a reflective film.

[0010] The thermally conductive insulating film has anti-slip textures, and the first temperature sensor is embedded in the thermally conductive insulating film at the edge of the light-transmitting hole.

[0011] The reflective film can be attached to the stage using adhesive backing.

[0012] The heating temperature range of the graphene heating device is 30℃-50℃.

[0013] The sand bath device includes a sand bath box, a second temperature sensor, a polyimide flexible heating film, and a container tank containing metal sand. The container tank is placed inside the sand bath box and the outer wall of the container tank is wrapped with a polyimide flexible heating film for heating the metal sand. The second temperature sensor is placed in the metal sand and the sand bath box and the second temperature sensor are electrically connected to a dual-channel electronic temperature controller via circuits.

[0014] The heating elements inside the polyimide flexible heating film are arranged in an S-shape with a spacing of 2cm-3cm.

[0015] The outer surface of the sand bath is coated with insulating material, and the inner surface of the sand bath is covered with heat insulation film.

[0016] The heating temperature range of the sand bath device is 20℃-70℃.

[0017] The dual-channel electronic temperature controller is equipped with a first display screen, a first setting key, and a first alarm light corresponding to the graphene heating device. The first display screen is used to display the current heating temperature of the graphene heating device in real time. The first setting key is used to set the heating temperature of the graphene heating device and switch the working mode. Pressing the temperature up and down keys once corresponds to the same temperature change. The first alarm light is used to trigger an alarm and activate power-off protection when the real-time temperature fed back by the first temperature sensor in the graphene heating device exceeds the set threshold.

[0018] The dual-channel electronic temperature controller is equipped with a second display screen, a second setting key, and a second alarm light corresponding to the sand bath device. The second display screen is used to display the current heating temperature of the sand bath device in real time. The second setting key is used to set the heating temperature of the sand bath device and switch the working mode. Pressing the temperature up and down keys once corresponds to the same temperature change. The second alarm light is used to trigger an alarm and activate power-off protection when the real-time temperature feedback from the second temperature sensor in the sand bath device exceeds the set threshold.

[0019] The cyclic graphene heating film, the polyimide flexible heating film, the first temperature sensor, and the second temperature sensor are all detachable modular structures.

[0020] This invention has the following advantages over the prior art:

[0021] 1. Functional integration: It has the heating functions of both microscope stage and metal sand bath, reducing equipment purchase costs and space occupation.

[0022] 2. Precise Dual Temperature Control: The dual heating structure combined with PLC closed-loop control achieves a temperature accuracy of ±0.5℃ in the working mode of the cyclic graphene heating film, ensuring stable temperature of biological samples on the stage; the polyimide flexible heating film working mode can achieve wide-range temperature adjustment to adapt to different temperature heating requirements.

[0023] 3. High adaptability: The ring-shaped graphene heating film with light-transmitting holes can be quickly connected to mainstream microscopes, making it highly adaptable. The material-carrying area is designed to be compatible with standard glass slides and petri dishes, making it easy to operate. The metal sand in the sand bath can be used to keep samples of different shapes warm before loading, and it is compatible with the preheating of consumables of different shapes.

[0024] 4. Environmental protection and safety: The insulating thermal conductive film, the sand bath box sprayed with an insulating layer, and the digital display board alarm prompts can improve the safety of equipment use. The cyclic graphene heating film and the polyimide flexible heating film can be modularly disassembled for daily maintenance, which is environmentally friendly and low cost.

[0025] 5. Promotional Value: Through structural optimization and functional integration, this temperature control device effectively solves the problem of the single function of traditional equipment. It is suitable for fields such as biological laboratories and medical testing, and has high practical value and promotional prospects. Attached Figure Description

[0026] Appendix Figure 1 A schematic diagram of the temperature control device for a microscope provided by this utility model;

[0027] Appendix Figure 2 A schematic diagram of the heating element layout structure within the polyimide flexible heating film provided by this utility model.

[0028] Wherein: 1—Graphene heating device; 11—Annular graphene heating film; 12—First temperature sensor; 13—Light-transmitting hole; 2—Sand bath device; 21—Sand bath box; 22—Second temperature sensor; 23—Polyimide flexible heating film; 24—Containing tank; 25—Metal sand; 3—Dual-channel electronic temperature controller; 31—First display screen; 32—First setting key; 33—First alarm light; 34—Second display screen; 35—Second setting key; 36—Second alarm light. Detailed Implementation

[0029] Exemplary embodiments will now be described more fully with reference to the accompanying drawings. However, these exemplary embodiments can be implemented in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that the present invention will be thorough and complete, and will fully convey the concept of the exemplary embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and therefore their detailed description will be omitted.

[0030] The terms “a,” “one,” “the,” and “the” are used to indicate the existence of one or more elements / components / etc.; the terms “including” and “having” are used to indicate an open-ended meaning of inclusion and that other elements / components / etc. may exist in addition to the listed elements / components / etc.

[0031] like Figure 1-2 The image shows a temperature control device for a microscope, comprising a sheet-like graphene heating device 1, a sand bath device 2, and a dual-channel electronic temperature controller 3. The graphene heating device 1 uses a ring-shaped graphene heating film 11 for heating, and the sand bath device 2 uses a polyimide flexible heating film 23 for heating. The sand bath device 2 is used to heat the sample and consumables before microscopic observation, and is connected to the dual-channel electronic temperature controller 3 via a circuit to receive temperature control from the dual-channel electronic temperature controller 3. The graphene heating device 1 is used to support the slide or petri dish and to maintain a relatively constant sample temperature during microscopic observation. The graphene heating device 1 is connected to the dual-channel electronic temperature controller 3 via a circuit to receive temperature control from the dual-channel electronic temperature controller 3. The dual-channel electronic temperature controller 3 is used to control the heating temperatures of the graphene heating device 1 and the sand bath device 2. The dual-channel electronic temperature controller 3 monitors the surface temperature of the cyclic graphene heating film 11 and the real-time temperature of the metal sand 25 in real time through temperature sensors, and controls the operation of the cyclic graphene heating film 11 and the polyimide flexible heating film 23 respectively.

[0032] The light-passing hole 13 in the middle of the annular graphene heating film 11 ensures that the light path for microscope observation is unobstructed. The sample-carrying area on the upper surface of the annular graphene heating film 11 is used to place observation slides or petri dishes, and is fixed by specimen clamps. The adhesive backing of the reflective film on the lower surface can be pasted onto the stage as needed to prevent slippage.

[0033] The outer surface of the sand bath 21 is coated with insulating material and the inner surface is covered with heat insulation film. The heat insulation film has adhesive backing and is used to stick to the inner wall of the sand bath. The sand bath 21 heats the receiving tank 24 through the polyimide flexible heating film 23 and transfers heat to the sample and consumables through the metal sand 25 to meet the requirements of rapid heating and directly heat the sample and consumables before microscopic observation.

[0034] The metal sand 25 inside the sand bath 21 is heated by the polyimide flexible heating film 23, rapidly completing heat exchange and ensuring a constant temperature for the sample and consumables before microscopic observation. The cyclic graphene heating film 11 can quickly and uniformly heat the stage, ensuring a relatively constant temperature for the sample under microscopic observation. For routine maintenance, the cyclic graphene heating film 11 and the polyimide flexible heating film 23 can be replaced as needed. To avoid contaminating the consumables, a lint-free wiping paper can be placed at the bottom of the consumables.

[0035] Typically, the cyclic graphene heating film 11 and the polyimide flexible heating film 23 need to work simultaneously to meet the needs of biological sample microscopic observation. Example

[0036] A temperature control device for a microscope includes a sheet-like graphene heating device 1, a sand bath device 2, and a dual-channel electronic temperature controller 3.

[0037] The graphene heating device 1 includes a ring-shaped graphene heating film 11 and a first temperature sensor 12. The ring-shaped graphene heating film 11 has a rectangular structure (10cm long, 5cm wide, and 0.4mm thick). The light-transmitting hole 13 in the middle of the ring-shaped graphene heating film 11 has a size of 20mm×20mm to ensure that the microscope objective can clearly observe the sample. The upper surface of the ring-shaped graphene heating film 11 is covered with a thermally conductive insulating film with anti-slip texture to enhance the friction between the slide and the film. It is also equipped with a fixing clip to accommodate slides or petri dishes of different sizes. The lower surface of the ring-shaped graphene heating film 11 is covered with a reflective film with adhesive backing to enhance its fixation effect with the stage.

[0038] The sand bath device 2 includes a sand bath box 21, a second temperature sensor 22, a polyimide flexible heating film 23, and a container 24 containing metal sand 25. The bottom and sides of the sand bath box 21 are covered with a heat insulation film, and the bottom and sides of the container 23 are covered with a 1.5mm thick polyimide flexible heating film 23. The heating elements inside the film are arranged in an S-shape with a spacing of 2-3cm to ensure uniform sand bath temperature.

[0039] The power of the cyclic graphene heating film 11 is 2W / cm. 2 It can heat the center of the thermally conductive insulating film's loading area to 50°C; the power of the polyimide flexible heating film 23 is 3W / cm². 2 It can heat metal sand with a diameter of 1mm and heat transfer medium 25 to 70℃.

[0040] The first temperature sensor 12 is a PT1000 platinum resistance thermometer with an accuracy of ±0.1℃, and is embedded in the center of the loading area of ​​the thermally conductive insulating film with anti-slip texture; the second temperature sensor 22 is a PT1000 platinum resistance thermometer with an accuracy of ±0.1℃, and is embedded in the center of the sand bath 21.

[0041] The first display screen 31 and the second display screen 34 on the dual-channel electronic temperature controller 3 can display the current temperature in real time. After pressing the first setting key 32 and the second setting key 35, the temperature setting and working mode switching are completed within 3 seconds. Pressing the temperature up and down keys once corresponds to a temperature change of 0.5℃. When the heating film temperature exceeds 50℃, the first alarm light 33 turns on, activating the power-off protection; when the sand bath temperature exceeds 80℃, the second alarm light 36 turns on, activating the power-off protection.

[0042] When in use, the cyclic graphene heating film 11 and the polyimide flexible heating film 23 need to work simultaneously to meet the needs of biological sample microscopic observation.

[0043] The temperature control device for microscopes provided by this utility model effectively solves the problem of the single function of traditional equipment through structural optimization and functional integration. It is suitable for fields such as biological laboratories and medical testing, and has high practical value and promotion prospects.

[0044] In this embodiment of the invention, the term "multiple" refers to two or more, unless otherwise explicitly defined. The terms "install," "connect," and "fix" should be interpreted broadly. For example, "connect" can mean a fixed connection, a detachable connection, or an integral connection. Those skilled in the art can understand the specific meaning of the above terms in this embodiment of the invention based on the specific circumstances.

[0045] In the description of the embodiments of this utility model, it should be understood that the terms "upper" and "lower" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this utility model and simplifying the description, and do not indicate or imply that the device or unit referred to must have a specific direction or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this utility model.

[0046] In this specification, the terms "an embodiment," "a preferred embodiment," etc., refer to a specific feature, structure, material, or characteristic described in connection with that embodiment or example, which is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0047] The above embodiments are only for illustrating the technical concept of this utility model and should not be construed as limiting the scope of protection of this utility model. Any modifications made to the technical solution based on the technical concept proposed by this utility model shall fall within the scope of protection of this utility model. Technologies not covered by this utility model can be implemented by existing technologies.

Claims

1. A temperature control device for a microscope, characterized in that: The temperature control device includes a sheet-like graphene heating element (1), a sand bath element (2), and a dual-channel electronic temperature controller (3), wherein, The sand bath device (2) is used to heat the sample and consumables before microscopic observation, and the sand bath device (2) is connected to the dual-channel electronic temperature controller (3) via a circuit to receive the temperature control of the dual-channel electronic temperature controller (3); The graphene heating device (1) is used to support the glass slide or petri dish and to keep the sample temperature relatively constant during microscope observation. The graphene heating device (1) is connected to the dual-channel electronic temperature controller (3) via a circuit to receive temperature control from the dual-channel electronic temperature controller (3). The dual-channel electronic temperature controller (3) is used to control the heating temperature of the graphene heating device (1) and the sand bath device (2).

2. The temperature control device for a microscope according to claim 1, characterized in that: The graphene heating device (1) includes an annular graphene heating film (11) and a first temperature sensor (12) which are electrically connected to a dual-channel electronic temperature controller (3) via a circuit. The annular graphene heating film (11) has a light-transmitting hole (13) in the middle that matches the microscope stage. The first temperature sensor (12) is used to monitor the heating temperature of the annular graphene heating film (11) and provide real-time feedback to the dual-channel electronic temperature controller (3).

3. The temperature control device for a microscope according to claim 2, characterized in that: The upper surface of the cyclic graphene heating film (11) is covered with a thermally conductive insulating film, and the lower surface is covered with a reflective film; the thermally conductive insulating film has anti-slip textures, and the first temperature sensor (12) is embedded on the thermally conductive insulating film at the edge of the light-transmitting hole (13).

4. The temperature control device for a microscope according to any one of claims 1-3, characterized in that: The heating temperature range of the graphene heating device (1) is 30℃-50℃.

5. The temperature control device for a microscope according to claim 1, characterized in that: The sand bath device (2) includes a sand bath box (21), a second temperature sensor (22), a polyimide flexible heating film (23), and a container (24) containing metal sand (25). The container (24) is placed inside the sand bath box (21), and the outer wall of the container (24) is covered with a polyimide flexible heating film (23) for heating the metal sand (25). The second temperature sensor (22) is placed in the metal sand (25), and the sand bath box (21) and the second temperature sensor (22) are electrically connected to a dual-channel electronic temperature controller (3) through lines.

6. The temperature control device for a microscope according to claim 5, characterized in that: The heating elements in the polyimide flexible heating film (23) are arranged in an S-shape with a spacing of 2cm-3cm.

7. The temperature control device for a microscope according to claim 5, characterized in that: The inner surface of the sand bath box (21) is covered with a heat insulation film.

8. The temperature control device for a microscope according to any one of claims 1, 5-7, characterized in that: The heating temperature range of the sand bath device (2) is 20℃-70℃.

9. The temperature control device for a microscope according to claim 1, characterized in that: The dual-channel electronic temperature controller (3) is equipped with a first display screen (31), a first setting key (32), and a first alarm light (33) corresponding to the graphene heating device (1). The first display screen (31) is used to display the current heating temperature of the graphene heating device (1) in real time. The first setting key (32) is used to set the heating temperature of the graphene heating device (1) and switch the working mode. Pressing the temperature up and down keys once corresponds to the same temperature change. The first alarm light (33) is used to alarm and start power-off protection when the real-time temperature exceeds the set threshold as reported by the first temperature sensor (12) in the graphene heating device (1).

10. The temperature control device for a microscope according to claim 1, characterized in that: The dual-channel electronic temperature controller (3) is equipped with a second display screen (34), a second setting key (35), and a second alarm light (36) corresponding to the sand bath device (2). The second display screen (34) is used to display the current heating temperature of the sand bath device (2) in real time. The second setting key (35) is used to set the heating temperature of the sand bath device (2) and switch the working mode. Pressing the temperature up and down keys once corresponds to the same temperature change. The second alarm light (36) is used to alarm and activate power-off protection when the real-time temperature exceeds the set threshold, based on feedback from the second temperature sensor (22) inside the sand bath device (2).