A high-efficiency separation column structure for liquid chromatography-tandem mass spectrometry
CN224422015UActive Publication Date: 2026-06-30JIANGSU PUERJING BIOPHARMACEUTICAL CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JIANGSU PUERJING BIOPHARMACEUTICAL CO LTD
- Filing Date
- 2025-05-12
- Publication Date
- 2026-06-30
AI Technical Summary
Technical Problem
The separation column of existing liquid chromatography-tandem mass spectrometry requires the entire column to be replaced when changing the stationary phase, which increases costs and makes the connection of the sieve plates inconvenient.
Method used
The column mechanism, including a fixed column, a blocking block, and a slot, enables quick replacement of the carrier tube through the cooperation of the moving block and the connecting spring. The design of the sealing ring and the protrusion simplifies the disassembly of the porous filter.
Benefits of technology
It reduces the cost and complexity of stationary phase replacement and improves the maintenance efficiency of the separation column.
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Smart Images
Figure CN224422015U_ABST
Abstract
This invention provides a high-efficiency separation column structure for liquid chromatography-tandem mass spectrometry (LC-MS / MS), relating to the field of LC-MS / MS. It includes a column mechanism comprising a fixed column, a blocking block, and a locking groove. Connecting caps are provided at both the upper and lower ends of the column mechanism. A stationary phase assembly is disposed inside the column mechanism. The stationary phase assembly includes a support tube, a positioning groove, a stationary phase body, a spring groove, a moving port, a connecting spring, a moving plate, a moving block, and a locking block. Fence plate assemblies are provided at both the upper and lower ends of the stationary phase assembly. The sieve plate assemblies include a fixing ring, a groove, a sealing groove, a porous filter, a sealing ring, and a protrusion. This invention reduces the cost of stationary phase body replacement by allowing only the support tube to be replaced, eliminating the need to replace the entire fixed column when replacing the stationary phase body. The positioning groove and blocking block position the support tube.
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