A stem cell storage device

Abstract

This utility model discloses a stem cell storage device, including a base with a lid and a support frame. The support frame includes multiple damping shock absorbers installed on the inner bottom surface of the base, with a housing attached to one end of each shock absorber. The housing is hollow and includes a bottom plane, a vertical surface, and multiple cylindrical slots. This utility model relates to the field of cell storage device technology. A reagent tube containing stem cells is placed in the housing. A cryogenic solution is stored in the housing, which, through freezing, provides a low-temperature environment for the reagent tube containing stem cells, preventing stem cell inactivation. Simultaneously, the damping shock absorbers absorb vibrations, preventing stem cell failure and ensuring the quality and efficiency of stem cell storage.

Description

Technical Field

[0001] This utility model relates to the field of cell storage device technology, specifically a stem cell storage device. Background Technology

[0002] Stem cells (SCs) are a type of pluripotent cell with the ability to self-renew. Under certain conditions, they can differentiate into various APSCs, which are primitive cells with the potential for self-replication and multi-directional differentiation. That is, stem cells maintain an undirected differentiation state and have the ability to proliferate. Under suitable conditions or given suitable signals, they can differentiate into various functional cells or tissues and organs. They are known in the medical field as "universal cells". Stem cells can be obtained from various sources, most commonly umbilical cord blood and tissue, dental pulp of deciduous or wisdom teeth, and adipose tissue. After collection, stem cells typically need to be stored at a temperature between 4°C and 25°C to ensure cell viability is not compromised. However, existing sample storage devices only provide room temperature environments. For example, a medical sample storage box with publication number CN222629880U includes a base plate with side plate one, side plate two, a front side plate, and a rear side plate on its top. Side plate one and side plate two are positioned opposite each other, and the front side plate and the rear side plate are positioned opposite each other. A top plate is fixedly connected to the inner top of side plate one, side plate two, the front side plate, and the rear side plate. This results in the collected stem cells being kept at room temperature for extended periods, leading to stem cell inactivation and affecting the quality of stem cell storage.

[0003] While existing technologies may already offer solutions to the aforementioned problems, this case aims to provide an alternative or replacement technical solution. Utility Model Content

[0004] To address the problems mentioned in the background art, this utility model is implemented through the following technical solution: a stem cell storage device, including a base, a box cover provided on the base, and a support frame provided on the base;

[0005] The support frame includes multiple damping shock absorbers, which are installed on the inner bottom surface of the base. Each damping shock absorber has a housing at one end. The housing is a hollow structure and includes a bottom plane, a vertical surface, and multiple cylindrical slots. The vertical surface is located at the edge of the bottom plane, and the multiple cylindrical slots are arranged in a rectangular array on the bottom plane. The housing is filled with coolant.

[0006] Each of the damping shock absorbers includes a reservoir, a plug rod is movably inserted into the upper wall of the reservoir, a plug head is installed at one end of the plug rod inside the reservoir, the plug head is movably fitted against the inner wall of the reservoir, a fluid passage hole is opened on the plug head, a housing is installed at the end of the plug rod outside the reservoir, a spring is provided between the plug head and the reservoir, and the reservoir is filled with damping fluid.

[0007] Preferably, a liquid inlet is inserted into the vertical surface, and a cap is installed at one end of the liquid inlet.

[0008] Preferably, a silicone mesh sleeve is fixedly installed on the inner wall of the plurality of cylindrical slot seats, and both the silicone mesh sleeve and the cylindrical slot seat have U-shaped notches.

[0009] Preferably, two through holes are symmetrically arranged on the vertical surface, and the box cover has clearance openings at the locations corresponding to the two through holes.

[0010] Preferably, a vibration damping sleeve is fixedly fitted on the outer wall of the facade, and the vibration damping sleeve is movably fitted to the inner wall of the base.

[0011] Preferably, a sealing ring is fixedly installed on the liquid reservoir, and the plug rod is movably fitted onto the sealing ring.

[0012] Preferably, a guide rod is installed on the inner wall of the liquid reservoir, the plug is movably fitted onto the guide rod, and the guide rod movably passes through the center of the spring.

[0013] Preferably, a water outlet is provided at the center of the lower wall of the base, a plug is inserted into the water outlet, an anti-slip pad is installed on the lower wall of the base, and a through hole is provided on the anti-slip pad corresponding to the plug.

[0014] Beneficial effects

[0015] This invention provides a stem cell storage device, which has the following advantages compared with the prior art: the reagent tube containing stem cells is placed in the box, and the box, which is composed of the bottom plane, the vertical surface and multiple cylindrical slots, stores cryosol. The cryosol provides a low temperature environment for the reagent tube containing stem cells, preventing stem cell inactivation. At the same time, the damping shock absorber protects the reagent tube containing stem cells from shock, preventing stem cell failure and ensuring the storage quality and efficiency of stem cells. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall three-dimensional structure of a stem cell storage device according to the present invention.

[0017] Figure 2 This is an exploded three-dimensional structural diagram of a stem cell storage device according to the present invention.

[0018] Figure 3 This is a schematic diagram of the front cross-sectional structure of a stem cell storage device according to the present invention.

[0019] In the diagram: 1. Base, 2. Cover, 3. Bottom plane, 4. Elevation, 5. Cylindrical groove seat, 6. Liquid reservoir, 7. Plug rod, 8. Plug head, 9. Liquid passage hole, 10. Spring, 11. Liquid inlet, 12. Sealing cap, 13. Silicone mesh sleeve, 14. Through hole, 15. Clearance notch, 16. Vibration damping sleeve, 17. Sealing ring, 18. Guide rod, 19. Seal, 20. Anti-slip pad, 21. Through hole. Detailed Implementation

[0020] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0021] Example: Please refer to Figure 1-3 A stem cell storage device includes a base 1, a box cover 2 on the base 1, and a support frame on the base 1.

[0022] It should be noted that the base 1 is used to install the support frame, the support frame is used to place the reagent tube containing stem cells, and the lid 2 is used to cover the top of the support frame.

[0023] Specifically, the support frame includes multiple damping shock absorbers, which are installed on the inner bottom surface of the base 1. Each damping shock absorber has a box at one end, which is a hollow structure. The box includes a bottom plane 3, a vertical surface 4, and multiple cylindrical slot seats 5. The vertical surface 4 is located at the edge of the bottom plane 3, and the multiple cylindrical slot seats 5 are arranged in a rectangular array on the bottom plane 3. The box is filled with coolant.

[0024] It should be noted that the liquid level of the cryo-fluid is located at two-thirds of the total height of the vertical surface 4, providing expansion space for freezing into a solid state. The device is placed in a common refrigerator freezer compartment or even a cryo-fluid device in a medical environment, with the temperature set above -40 degrees Celsius. The cryo-fluid can be a 10% propylene glycol aqueous solution. Then, the device is taken out and placed in the target position via the base 1. The reagent tube containing the stem cells is inserted into the cylindrical slot 5 to provide a low-temperature environment for the reagent tube containing the stem cells, preventing stem cell inactivation and ensuring the storage quality and efficiency of the stem cells.

[0025] Specifically, each damping shock absorber includes a reservoir 6, a plug rod 7 is movably inserted into the upper wall of the reservoir 6, a plug head 8 is installed at one end of the plug rod 7 inside the reservoir 6, the plug head 8 is movably fitted against the inner wall of the reservoir 6, a fluid passage hole 9 is opened on the plug head 8, a box is installed at the end of the plug rod 7 outside the reservoir 6, a spring 10 is provided between the plug head 8 and the reservoir 6, and the reservoir 6 is filled with damping fluid;

[0026] It should be noted that the damping fluid can be the commonly available antifreeze glass cleaner that can withstand temperatures as low as -40 degrees Celsius. When the device is placed in the freezer, the antifreeze will freeze, but the damping fluid will not. After the stem cells are collected, if vibration occurs when the device is moved, the box will move the stopper rod 7 and the stopper 8 in the reservoir 6. When the stopper 8 moves downward in the reservoir 6, the damping fluid below the stopper 8 flows through the liquid passage 9 to the chamber above the stopper 8. The flow of the damping fluid will generate resistance. At the same time, the downward movement of the stopper 8 will compress the spring 10. The spring 10 will absorb and store some kinetic energy. Under the action of the spring 10's rebound force, the stopper 8 will be pushed upward to reset, which will also generate resistance and play a role in damping and shock absorption. This will prevent the reagent tube containing stem cells in the cylindrical slot 5 from being subjected to large vibrations and prevent the stem cells from being deactivated due to vibration.

[0027] As a preferred and further option, a liquid inlet 11 is inserted into the facade 4, and a cap 12 is installed at one end of the liquid inlet 11 for adding refrigerant.

[0028] Preferably, a silicone mesh sleeve 13 is fixedly installed on the inner wall of multiple cylindrical slots 5. When a reagent tube containing stem cells is inserted into the cylindrical slot 5, the silicone mesh sleeve 13 tightly wraps the reagent tube. The silicone mesh sleeve 13 increases the friction between the reagent tube and the cylindrical slot 5, preventing the reagent tube from moving up and down in the cylindrical slot 5 when the device vibrates, thus improving the vibration reduction effect. Both the silicone mesh sleeve 13 and the cylindrical slot 5 are provided with U-shaped notches to facilitate the removal of the reagent tube by the staff.

[0029] As a preferred and further option, two through holes 14 are symmetrically arranged on the facade 4 to facilitate the staff to hold the device. Since the liquid level of the coolant is located at two-thirds of the entire facade 4, there is no low-temperature coolant at the through hole 14, so it will not cause the staff's hands to become cold. The cover 2 is provided with clearance notches 15 at the locations corresponding to the two through holes 14 to provide space for the staff to hold the through hole 14.

[0030] As a preferred and further option, a vibration damping sleeve 16 is fixedly fitted on the outer wall of the facade 4. The vibration damping sleeve 16 is movably fitted to the inner wall of the base 1 to isolate the vibration transmission between the facade 4 and the base 1.

[0031] As a preferred and further option, a sealing ring 17 is fixedly installed on the liquid reservoir 6, and the plug rod 7 is movably fitted onto the sealing ring 17 to prevent leakage at the connection between the liquid reservoir 6 and the plug rod 7.

[0032] As a preferred and further option, a guide rod 18 is installed on the inner wall of the liquid reservoir 6, and the plug 8 is movably fitted onto the guide rod 18, with the guide rod 18 movably passing through the center of the spring 10.

[0033] As a preferred and further option, a water outlet is provided at the center of the lower wall of the base 1, and a plug 19 is inserted into the water outlet. An anti-slip pad 20 is installed on the lower wall of the base 1, and through holes 21 are provided on the anti-slip pad 20 corresponding to the plug 19. When the frozen liquid melts, the water droplets generated on the outer wall of the vertical surface 4 drip onto the base 1 and can be discharged by removing the plug 19. The anti-slip pad 20 is used to improve the friction of the lower wall of the base 1.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A stem cell storage device, comprising a base (1) and a lid (2) disposed on the base (1), characterized in that, A support frame is provided on the base (1); The support frame includes multiple damping shock absorbers, which are installed on the inner bottom surface of the base (1). Each damping shock absorber has a box at one end. The box is a hollow structure and includes a bottom plane (3), a vertical surface (4), and multiple cylindrical slot seats (5). The vertical surface (4) is located at the edge of the bottom plane (3). The multiple cylindrical slot seats (5) are arranged in a rectangular array on the bottom plane (3). The box is filled with coolant. Each of the damping shock absorbers includes a reservoir (6), a plug rod (7) is movably inserted into the upper wall of the reservoir (6), a plug head (8) is installed at one end of the plug rod (7) inside the reservoir (6), the plug head (8) is movably attached to the inner wall of the reservoir (6), a liquid passage hole (9) is opened on the plug head (8), a box is installed at the end of the plug rod (7) outside the reservoir (6), a spring (10) is provided between the plug head (8) and the reservoir (6), and the reservoir (6) is filled with damping fluid.

2. The stem cell storage device according to claim 1, characterized in that, An inlet (11) is inserted into the facade (4), and a cap (12) is installed at one end of the inlet (11).

3. A stem cell storage device according to claim 1, characterized in that, Silicone mesh sleeves (13) are fixedly installed on the inner wall of multiple cylindrical slot seats (5), and U-shaped notches are opened on both the silicone mesh sleeves (13) and the cylindrical slot seats (5).

4. A stem cell storage device according to claim 1, characterized in that, Two through holes (14) are symmetrically arranged on the facade (4), and clearance openings (15) are provided on the box cover (2) at the locations corresponding to the two through holes (14).

5. A stem cell storage device according to claim 1, characterized in that, A vibration damping sleeve (16) is fixedly fitted on the outer wall of the facade (4), and the vibration damping sleeve (16) is movably fitted to the inner wall of the base (1).

6. A stem cell storage device according to claim 1, characterized in that, A sealing ring (17) is fixedly installed on the liquid reservoir (6), and the plug rod (7) is movably attached to the sealing ring (17).

7. A stem cell storage device according to claim 1, characterized in that, A guide rod (18) is installed on the inner wall of the liquid reservoir (6), and the plug (8) is movably fitted on the guide rod (18). The guide rod (18) movably passes through the center of the spring (10).

8. A stem cell storage device according to claim 1, characterized in that, A water outlet is provided at the center of the lower wall of the base (1), and a plug (19) is inserted into the water outlet. An anti-slip pad (20) is installed on the lower wall of the base (1), and a through hole (21) is provided on the anti-slip pad (20) corresponding to the plug (19).

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