A fibrinogen concentration instant testing device
By using a flip-top design and a rotating connector, the problem of misalignment between the reaction strip and the wicking strip was solved, enabling accurate detection of fibrinogen concentration in an instantaneous testing device and reducing operational errors and human interference.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- ACADEMY OF MILITARY MEDICAL SCIENCES
- Filing Date
- 2025-06-19
- Publication Date
- 2026-07-03
Smart Images
Figure CN224456758U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical device technology, and in particular to a device for instant testing of fibrinogen concentration. Background Technology
[0002] Fibrinogen is a plasma glycoprotein synthesized by the liver, playing a central role in the coagulation cascade. It can be converted into fibrin by thrombin, forming a thrombus. Fibrinogen concentration measurement is an important indicator for assessing coagulation function and is widely used in clinical diagnosis and treatment monitoring. It is crucial in hemorrhagic diseases (such as hypofibrinogenemia and DIC), thrombosis risk prediction (such as hyperfibrinogenemia), liver disease assessment, and perioperative management. Furthermore, its characteristics as an acute-phase reactive protein are also related to physiological and pathological states such as inflammation, trauma, and pregnancy. Commonly used detection methods include the Claus method, immunoturbidimetry, and prothrombin time (PT) derivatization methods, providing a basis for individualized anticoagulation or replacement therapy through quantitative analysis.
[0003] However, existing POCT test cards typically use a pull-out design, which often leads to misalignment between the "reaction strip" and the "core strip" during use, resulting in inaccurate contact and affecting the accuracy of the test results.
[0004] Therefore, a device for real-time testing of fibrinogen concentration is provided to solve the aforementioned problems existing in the prior art. Utility Model Content
[0005] The purpose of this invention is to provide a device for instant testing of fibrinogen concentration to solve the problems existing in the prior art, enabling precise contact between the reaction strip and the wick strip and reducing operational errors.
[0006] To achieve the above objectives, this utility model provides the following solution:
[0007] This invention provides a device for instant testing of fibrinogen concentration, comprising a support portion and a flip-top portion. One end of the support portion is provided with a sample reaction hole for placing a sample to be tested inside the sample reaction hole, and a reaction strip is provided inside the sample reaction hole, the reaction strip contacting the sample to be tested. One side of the flip-top portion is rotatably connected to one side of the support portion via a rotating connector, so that the flip-top portion can be fastened or opened with the support portion. A wicking strip is provided on the flip-top portion, and when the flip-top portion is fastened with the support portion, the wicking strip can contact the reaction strip to absorb the uncoagulated liquid in the sample to be tested.
[0008] Preferably, both the supporting part and the flip-cover part are elongated structures, and one side of the flip-cover part along its length direction is rotatably connected to the other side of the flip-cover part along its length direction through the rotating connector, so that the flip-cover part can be fastened to or opened with the supporting part.
[0009] Preferably, the rotating connector includes a hinge seat, which is disposed on the flip cover and is rotatably connected to the bearing portion via a rotating shaft.
[0010] Preferably, multiple rotating connectors are arranged at intervals along the length of the flip cover.
[0011] Preferably, the carrier portion is further provided with a first test strip groove, the first test strip groove being located on the side of the sample reaction hole near the core strip, and the end of the reaction strip away from the sample to be tested being located in the first test strip groove.
[0012] Preferably, the width of the first test strip groove is greater than the width of the reaction strip, and there is a gap between the two sides of the reaction strip and the sidewall of the first test strip groove.
[0013] Preferably, limit blocks are provided on both sides of the first test paper groove along its length.
[0014] Preferably, a second test paper groove is provided on the flip cover along its length, and the wick strip is disposed in the second test paper groove.
[0015] Preferably, the second test strip groove is further provided with a scale line on one side along its length direction for reading the wicking length of the wicking strip.
[0016] Preferably, the bottom of the flip cover is provided with a fixing post, and the top of the support part is provided with a corresponding fixing hole. The fixing post can be inserted into the corresponding fixing hole to fix the flip cover and the support part.
[0017] The present invention achieves the following technical advantages over the prior art:
[0018] The fibrinogen concentration instant testing device of this utility model includes a support part and a flip-top part. One side of the flip-top part is rotatably connected to one side of the support part through a rotating connector, so that the flip-top part can be fastened or opened with the support part. The flip-top design realizes the accurate fixing of the position of the reaction strip and the wick strip, ensuring precise contact between the two, thereby reducing operational errors. Moreover, it can make the pressure distribution between the reaction strip and the wick strip uniform and constant, further reducing the interference of human operation errors on the wick absorption effect of the test strip. Attached Figure Description
[0019] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0020] Figure 1 This is a top view of the fibrinogen concentration instant testing device in an embodiment of this utility model;
[0021] Figure 2 This is a front view of the fibrinogen concentration instant testing device in an embodiment of this utility model;
[0022] Figure 3 This is a top view of the flip cover in an embodiment of the present utility model;
[0023] Figure 4 This is a right view of the flip cover in an embodiment of the present utility model;
[0024] Figure 5 This is a front view of the flip cover in an embodiment of the present utility model;
[0025] Figure 6 This is a bottom view of the flip cover in an embodiment of the present utility model;
[0026] Figure 7 This is a top view of the bearing portion in an embodiment of this utility model;
[0027] Figure 8 This is a front view of the support portion in an embodiment of this utility model.
[0028] In the diagram: 100 - Fibrinogen concentration instant testing device, 1 - Flip-top, 2 - Core strip, 3 - Scale line, 4 - Supporting part, 5 - Second test paper slot, 6 - Hinge seat, 7 - Fixing column, 8 - Sample reaction hole, 9 - Limiting block, 10 - Fixing hole. Detailed Implementation
[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0030] The purpose of this invention is to provide a device for instant testing of fibrinogen concentration to solve the problems existing in the prior art, enabling precise contact between the reaction strip and the wick strip and reducing operational errors.
[0031] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.
[0032] Example 1
[0033] like Figures 1-8 As shown, this embodiment provides a fibrinogen concentration instant testing device 100, which mainly includes a support part 4 and a flip-top part 1. One end of the support part 4 is provided with a sample reaction hole 8, which is used to place the sample to be tested. A reaction strip is provided in the sample reaction hole 8, and the reaction strip is in contact with the sample to be tested. One side of the flip-top part 1 is rotatably connected to one side of the support part 4 through a rotating connector, so that the flip-top part 1 can be fastened or opened with the support part 4. A wicking strip 2 is provided on the flip-top part 1. When the flip-top part 1 is fastened with the support part 4, the wicking strip 2 can contact the reaction strip to absorb the uncoagulated liquid in the sample to be tested.
[0034] In this embodiment, the fibrinogen concentration instant testing device 100 includes a support part 4 and a flip-top part 1. One side of the flip-top part 1 is rotatably connected to one side of the support part 4 via a rotating connector, so that the flip-top part 1 can be engaged or disengaged from the support part 4. The flip-top design achieves accurate fixation of the positions of the reaction strip and the wick strip 2, ensuring precise contact between the two and reducing operational errors. Moreover, it enables a uniform and constant pressure distribution between the reaction strip and the wick strip 2, further reducing the interference of human operational errors on the wick absorption effect of the test strip.
[0035] In this embodiment, the fibrinogen concentration instant testing device 100 is generally a cuboid structure. The supporting part 4 and the flip cover part 1 are approximately rectangular strip structures. The flip cover part 1 is rotatably connected to the supporting part 4 along its length direction by a rotating connector, so that the flip cover part 1 can be fastened to or opened with the supporting part 4.
[0036] Furthermore, the rotating connector can be selected according to specific working needs. For example, the rotating connector may include a hinge seat 6, which is disposed on the flip cover 1 and is rotatably connected to the support part 4 via a rotating shaft. The rotating shaft extends along the length direction of the flip cover 1 to realize the rotatable connection between the flip cover 1 and the support part 4. Alternatively, other rotating connectors, such as hinges, may be selected.
[0037] In this embodiment, multiple rotating connectors can be arranged sequentially and evenly along the length of the flip cover 1 to improve the stability of the rotating connection.
[0038] In this embodiment, the carrier part 4 is also provided with a first test strip groove, which is located on the side of the sample reaction hole 8 near the core strip 2, and the end of the reaction strip away from the sample to be tested is located in the first test strip groove.
[0039] In this embodiment, the width of the first test strip groove is greater than the width of the reaction strip, so that there is a gap between the two sides of the reaction strip and the sidewall of the first test strip groove, so as to avoid capillary action interfering with the detection results; wherein, the width of the first test strip groove is preferably 3mm, and the width of the reaction strip is slightly smaller than the width of the first test strip groove.
[0040] Furthermore, limiting blocks 9 are provided on both sides of the first test strip groove along the length direction to limit the reaction strip and the wick strip 2.
[0041] In this embodiment, a second test strip groove 5 is provided on the flip cover 1 along its length direction, and the core suction strip 2 is disposed in the second test strip groove 5. The width of the second test strip groove 5 and the width of the core suction strip 2 are matched, and both are preferably 2mm.
[0042] In this embodiment, a scale line 3 is also provided on one side of the second test strip groove 5 along its length direction for reading the wicking length of the wicking strip 2.
[0043] Before testing, the flip-top 1 is opened, and the reaction strip and the wicking strip 2 are separated. During testing, the flip-top 1 is rotated to bring the two into contact, triggering the liquid wicking process of the wicking strip 2. Finally, the FIB concentration can be determined by reading the wicking length through the scale line 3.
[0044] In this embodiment, a fixing post 7 is provided at the bottom of the flip cover 1, and a fixing hole 10 is provided at the top of the supporting part 4. The fixing post 7 can be inserted into the corresponding fixing hole 10 to fix the flip cover 1 and the supporting part 4, thereby improving the stability when fastening.
[0045] The fixing posts 7 are located on the side of the flip cover 1 away from the rotating connector, and are spaced apart along the length of the flip cover 1. The fixing holes 10 are located on the side of the bearing part 4 away from the rotating connector, and are spaced apart along the length of the bearing part 4. The overall stability is further improved by the cooperation of multiple sets of fixing posts 7 and fixing holes 10.
[0046] The method of using the fibrinogen concentration instantaneous testing device 100 in this embodiment is as follows:
[0047] First, diluted plasma is added to the sample reaction well 8 of the carrier section 4. Thrombin in the reaction strip specifically catalyzes the conversion of FIB in the plasma into fibrin monomers, which then polymerize into fibrin clots with a three-dimensional network structure. This fibrin network can firmly adhere to the surface of the plant fiber in the reaction strip, forming an effective blocking effect.
[0048] Next, after the reaction is complete, the wick strip 2 is brought into full contact with the reaction strip by rotating the flip-top 1. During the closing process of the flip-top 1, the wick strip 2 draws in the uncoagulated liquid through capillary action. Finally, by accurately measuring the extension length of the liquid in the wick strip 2, the concentration of FIB in the plasma can be quantitatively detected.
[0049] This utility model uses specific examples to illustrate its principles and implementation methods. The above description of the embodiments is only for the purpose of helping to understand the method and core idea of this utility model. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the idea of this utility model. In summary, the content of this specification should not be construed as a limitation of this utility model.
Claims
1. A fibrinogen concentration point-of-care device, characterized by: The device includes a support portion and a flip-top portion. One end of the support portion is provided with a sample reaction hole for placing a sample to be tested inside the sample reaction hole, and a reaction strip is provided inside the sample reaction hole, with the reaction strip in contact with the sample to be tested. One side of the flip-top portion is rotatably connected to one side of the support portion via a rotating connector, so that the flip-top portion can be fastened or opened with the support portion. A wicking strip is provided on the flip-top portion, and when the flip-top portion is fastened with the support portion, the wicking strip can contact the reaction strip to absorb the unsolidified liquid in the sample to be tested.
2. The fibrinogen concentration point-of-care device of claim 1, wherein: Both the supporting part and the flip-cover part are elongated structures. The flip-cover part is rotatably connected to the supporting part along its length by the rotating connector, so that the flip-cover part can be fastened to or opened by the supporting part.
3. The fibrinogen concentration point-of-care device of claim 2, wherein: The rotating connector includes a hinge seat, which is disposed on the flip cover and is rotatably connected to the bearing portion via a rotating shaft.
4. The fibrinogen concentration point-of-care device according to claim 2 or 3, characterized in that: Multiple rotating connectors are arranged at intervals along the length of the flip cover.
5. The fibrinogen concentration point-of-care device of claim 1, wherein: The carrier part is also provided with a first test strip groove, which is located on the side of the sample reaction hole near the core strip, and the end of the reaction strip away from the sample to be tested is located in the first test strip groove.
6. The fibrinogen concentration point-of-care device of claim 5, wherein: The width of the first test strip groove is greater than the width of the reaction strip, and there are gaps between the two sides of the reaction strip and the sidewalls of the first test strip groove.
7. The fibrinogen concentration point-of-care device according to claim 5 or 6, characterized in that: Limiting blocks are also provided on both sides of the first test paper groove along its length.
8. The fibrinogen concentration point-of-care device of claim 1, wherein: The flip-top portion has a second test paper slot along its length, and the wick strip is disposed in the second test paper slot.
9. The fibrinogen concentration point-of-care device of claim 8, wherein: The second test strip groove is also provided with a scale line on one side along its length direction for reading the wicking length of the wick strip.
10. The fibrinogen concentration point-of-care device of claim 1, wherein: The bottom of the flip cover is also provided with a fixing post, and the top of the support part is provided with a corresponding fixing hole. The fixing post can be inserted into the corresponding fixing hole to fix the flip cover and the support part.