A plasmin-alpha 2 plasmin inhibitor complex assay kit

Abstract

A kind of fibrinolysin-alpha 2 plasmin inhibitor complex determination kit, including circular reagent kit, rotating vertical rod, support plate, rotating gear disc, outer ring-shaped supporting plate, inner ring-shaped supporting plate, U-shaped connecting rod, vertical connecting rod, annular limiting rod, support table, reagent tube, the lower part of the circular reagent kit has reagent kit lower plate, circular reagent kit has reagent kit inner cavity, two groups of holding grooves are formed in holding groove bottom, ball is adapted to holding groove, ball is inserted into holding groove, ball rolls in holding groove, two groups of balls are distributed in reagent kit inner cavity, one end of U-shaped connecting rod is connected with outer ring-shaped supporting plate, the other end of U-shaped connecting rod is connected with inner ring-shaped supporting plate, multiple U-shaped connecting rods are distributed between outer ring-shaped supporting plate and inner ring-shaped supporting plate, the axis of outer ring-shaped supporting plate and inner ring-shaped supporting plate coincides, and outer ring-shaped supporting plate and inner ring-shaped supporting plate are inserted into reagent kit inner cavity.

Description

Technical Field

[0001] This invention relates to the field of plasmin-α2 plasmin, and more particularly to a plasmin-α2 plasmin inhibitor complex assay kit. Background Technology

[0002] An existing patent (publication number: CN114212379B) discloses a reagent kit comprising: an outer protective member having an open receiving cavity with a guide ramp inside the receiving cavity; and a placement assembly movably disposed within the receiving cavity, the placement assembly including a reagent tube placement member having at least one placement through-hole extending through both the upper and lower sides of the reagent tube placement member for the reagent tube to pass through; wherein, the reagent tube placement member can be operably moved within the receiving cavity in a predetermined direction, and during the movement of the reagent tube placement member in the predetermined direction, the reagent tube can be pushed by the guide ramp and moved toward the outside of the open cavity. However, this reagent kit is in an open state, and when used for the assay of plasmin-α2 plasmin inhibitor complex, it does not provide protection for the reagent tubes, which are easily collided with each other or fall out of the kit during transportation. Summary of the Invention

[0003] This invention addresses the aforementioned shortcomings of existing technologies by providing a plasmin-α2 plasmin inhibitor assay kit. In this kit, the inner annular support plate rotates to bring the lower part of the reagent tube, passing through the support plate, into contact with the support platform. The support platform lifts the reagent tube, allowing its upper part to pass through the support plate and exceed the upper surface of the circular reagent kit. The reagent tube can then be removed for plasmin inhibitor detection. This structure allows for the sequential removal of multiple reagents from the circular kit at intervals. The semi-enclosed upper structure prevents the kit from falling out during transport.

[0004] The objective of this utility model is achieved through the following technical solution:

[0005] A plasmin-α2 plasmin inhibitor complex assay kit includes a circular kit, a rotating vertical rod, a support plate, a rotating toothed disc, an outer annular support plate, an inner annular support plate, a U-shaped connecting rod, a vertical connecting rod, an annular limiting rod, a support platform, and reagent tubes. The circular kit has a lower kit plate at its bottom and an inner cavity. The bottom of the holding tank has two sets of holding slots. A sphere is adapted to the holding slot and is inserted into the holding slot. The sphere rolls in the holding slot. The two sets of spheres are distributed in the inner cavity of the kit. One end of the U-shaped connecting rod is connected to the outer annular support plate, and the other end of the U-shaped connecting rod is connected to the inner annular support plate. Multiple U-shaped connecting rods are distributed between the outer annular support plate and the inner annular support plate. The outer annular support plate and the inner annular support plate have coincident axes and are both inserted into the inner cavity of the kit.

[0006] The outer side of the outer annular tray is in contact with the outer side of the inner cavity of the reagent kit, and the inner side of the inner annular tray is in contact with the inner side of the inner cavity of the reagent kit. The lower part of the vertical connecting rod is connected to the outer annular tray, and the side of the vertical connecting rod is connected to an annular limiting rod. A set of annular limiting rods are distributed on the side of the vertical connecting rod, and multiple vertical connecting rods are evenly distributed on the outer annular tray.

[0007] The container has an arc-shaped clearance hole on its side. The support plate is connected to the side fixing plate. The side fixing plate is connected to the circular reagent kit. The rotating gear disk fits into the support plate. The lower part of the rotating gear disk has a gear disk lower column. The gear disk lower column is inserted into the support plate and rotates inside the support plate. The rotating vertical rod passes through the support plate and connects to the rotating gear disk. The upper part of the rotating vertical rod is connected to the rotating handle. Beneficial effects

[0008] 1. In this invention, the sphere is placed inside the holding tank, which positions the sphere. The outer annular support plate is connected to the inner annular support plate via multiple U-shaped connecting rods. Two sets of spheres support the outer and inner annular support plates respectively, making the rotation of the outer and inner annular support plates within the reagent kit cavity smoother. A set of annular limiting rods is supported and fixed by a vertical connecting rod. During use, the reagent tube is inserted into the annular limiting rods, which position the reagent tube and prevent it from tilting during the use of the plasmin-α2 plasmin inhibitor complex assay kit, keeping the reagent tube vertical. The support plate is installed and fixed on the circular reagent kit via a side fixing plate. The lower column of the toothed disk cooperates with the rotating vertical rod to position the axis of the rotating toothed disk, fixing the lateral and vertical positions of the rotating toothed disk without affecting its rotation. The rotation of the toothed disk can be controlled by rotating the handle on the outside of the circular reagent kit.

[0009] 2. In this invention, a rotating toothed disc passes through an arc-shaped clearance hole and meshes with the inner side of an inner annular support plate. The rotation of the toothed disc controls the rotation of the inner annular support plate, thereby causing multiple reagent tubes to rotate inside the circular reagent kit. The support platform is installed and fixed inside the circular reagent kit, located below the support plate and between the outer and inner annular support plates. When used for the assay of plasmin-α2 plasmin inhibitor complex, the rotation of the inner annular support plate is controlled so that the lower part of the reagent tube passing through the support plate comes into contact with the support platform. The support platform lifts the reagent tube so that the upper part of the reagent tube passes through the support plate and is higher than the upper surface of the circular reagent kit. At this time, the reagent tube can be removed to detect the plasmin inhibitor inside. This structure allows multiple reagent tubes to be removed sequentially from the circular reagent kit. Attached Figure Description

[0010] Figure 1 This is a top view of the plasmin-α2 plasmin inhibitor complex assay kit of the present invention.

[0011] Figure 2This is a top view of the plasmin-α2 plasmin inhibitor complex assay kit of the present invention.

[0012] Figure 3 This is a side cross-sectional view of the plasmin-α2 plasmin inhibitor complex assay kit of the present invention.

[0013] Figure 4 This is a top cross-sectional view of the plasmin-α2 plasmin inhibitor complex assay kit of the present invention.

[0014] Figure 5 This is a schematic diagram of the circular reagent kit structure described in this utility model.

[0015] Figure 6 This is a schematic diagram of the outer annular support plate, inner annular support plate, and annular limiting rod structure described in this utility model. Detailed Implementation

[0016] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments:

[0017] Example 1:

[0018] A plasmin-α2 plasmin inhibitor complex assay kit includes a circular reagent kit 01, a rotating vertical rod 05, a support plate 07, a rotating toothed disk 08, an outer annular support plate 12, an inner annular support plate 13, a U-shaped connecting rod 14, a vertical connecting rod 15, an annular limiting rod 16, a support platform 17, and a reagent tube 19. The circular reagent kit 01 has a lower reagent kit plate 04 at its lower part and an inner cavity 02. The bottom of the holding tank 03 has two sets of holding slots 03. A sphere 18 is adapted to the holding slot 03 and is inserted into it. The container 03 contains a ball 18 that rolls within it. The ball 18 is positioned inside the container 03, and the container 03 positions the ball 18. Two sets of balls 18 are distributed within the inner cavity 02 of the reagent kit. One end of a U-shaped connecting rod 14 is connected to an outer annular support plate 12, and the other end of the U-shaped connecting rod 14 is connected to an inner annular support plate 13. Multiple U-shaped connecting rods 14 are distributed between the outer annular support plate 12 and the inner annular support plate 13. The outer annular support plate 12 and the inner annular support plate 13 have their axes coincident, and both the outer annular support plate 12 and the inner annular support plate 13 are inserted into the inner cavity 02 of the reagent kit.

[0019] Example 2:

[0020] The outer annular support plate 12 of this invention is in contact with the outer side of the inner cavity 02 of the reagent kit, and the inner side of the inner annular support plate 13 is in contact with the inner side of the inner cavity 02 of the reagent kit. The lower part of the vertical connecting rod 15 is connected to the outer annular support plate 12, and the side of the vertical connecting rod 15 is connected to the annular limiting rod 16. The vertical connecting rod 15 supports and fixes a set of annular limiting rods 16. A set of annular limiting rods 16 are distributed on the side of the vertical connecting rod 15, and multiple vertical connecting rods 15 are evenly distributed on the outer annular support plate 12.

[0021] Example 3:

[0022] The container 03 of this utility model has an arc-shaped clearance hole 10 on its side. The support plate 07 is connected to the side fixing plate 20. The side fixing plate 20 is connected to the circular reagent kit 01. The support plate 07 is installed and fixed on the circular reagent kit 01 through the side fixing plate 20. The lower column 09 of the toothed disk cooperates with the rotating vertical rod 05 to position the axis of the rotating toothed disk 08, so that the horizontal and vertical positions of the rotating toothed disk 08 are fixed without affecting the rotation of the rotating toothed disk 08. The rotation of the rotating toothed disk 08 can be controlled by rotating the rotating handle 06 on the outside of the circular reagent kit 01. The rotating toothed disk 08 is in contact with the support plate 07. The lower part of the rotating toothed disk 08 has a lower column 09. The lower column 09 is inserted into the support plate 07 and rotates inside the support plate 07. The rotating vertical rod 05 passes through the support plate 07 and connects to the rotating toothed disk 08. The upper part of the rotating vertical rod 05 is connected to the rotating handle 06.

[0023] Example 4:

[0024] The rotating gear 08 of this invention is inserted into the arc-shaped relief hole 10. The rotating gear 08 meshes with the inner side of the inner annular support plate 13. The rotating gear 08 passes through the arc-shaped relief hole 10 and meshes with the inner side of the inner annular support plate 13. The rotation of the rotating gear 08 controls the rotation of the inner annular support plate 13, thereby causing multiple reagent tubes 19 to rotate inside the circular reagent kit 01. The upper surfaces of the two sets of spheres 18 are respectively in contact with the bottom surfaces of the outer annular support plate 12 and the inner annular support plate 13. The two sets of spheres 18 support the outer annular support plate 12 and the inner annular support plate 13 respectively. The spheres 18 make the rotation of the outer annular support plate 12 and the inner annular support plate 13 smoother in the inner cavity 02 of the reagent kit. The reagent tubes 19 are inserted into the annular limiting rod 16. The lower surface of the reagent tubes 19 is in contact with the outer annular support plate 12 and the inner annular support plate 13. The vertical connecting rod A set of annular limiting rods 16 are used to support and fix the reagent kit 01. The lower part of the support platform 17 is connected to the circular reagent kit 01. The upper surface of the support platform 17 is in contact with the lower surface of the reagent tube 19. The upper part of the reagent tube 19 passes through the support plate 07. The support platform 17 is installed and fixed inside the circular reagent kit 01. The support platform 17 is located below the support plate 07 and between the outer annular support plate 12 and the inner annular support plate 13. During use, the inner annular support plate 13 is rotated so that the lower part of the reagent tube 19 passing through the support plate 07 is in contact with the support platform 17. The support platform 17 lifts the reagent tube 19 so that the upper part of the reagent tube 19 passes through the support plate 07 and is higher than the upper surface of the circular reagent kit 01. At this time, the reagent tube 19 can be taken out to detect the plasmin inhibitor inside. This structure can sequentially remove multiple spaced reagents from the circular reagent kit 01.

[0025] Example 5:

[0026] The installation steps of this utility model are as follows: First, insert the lower column 09 of the gear plate into the support plate 07. Then, pass the rotating vertical rod 05 through the support plate 07 and connect it to the rotating gear plate 08. Connect the side of the support plate 07 to the side fixing plate 20. Connect the two ends of the side fixing plate 20 to the circular reagent kit 01. Insert the sphere 18 into the holding slot 03. Connect the lower part of the support platform 17 to the circular reagent kit 01. Connect the two ends of the U-shaped connecting rod 14 to the outer annular support plate 12 and the inner annular support plate 13, respectively. Connect the lower part of the vertical connecting rod 15 to the outer annular support plate 12. Connect the side of the vertical connecting rod 15 to the annular limiting rod 16. Insert the outer annular support plate 12 and the inner annular support plate 13 into the inner cavity 02 of the reagent kit. Insert the reagent tube 19 into the annular limiting rod 16.

[0027] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A kit for detecting plasmin-α2 plasmin inhibitor complex, characterized in that... The kit includes a circular reagent kit (01), a rotating vertical rod (05), a support plate (07), a rotating gear plate (08), an outer annular support plate (12), an inner annular support plate (13), a U-shaped connecting rod (14), a vertical connecting rod (15), an annular limiting rod (16), a support platform (17), and a reagent tube (19). The circular reagent kit (01) has a lower reagent kit plate (04) at its lower part and an inner cavity (02) for the reagent kit. The bottom of the holding tank (03) has two sets of holding tanks (03). A sphere (18) is adapted to the holding tank (03). 18) Insert into the holding slot (03), the ball (18) rolls in the holding slot (03), the two sets of balls (18) are distributed in the inner cavity (02) of the reagent kit, one end of the U-shaped connecting rod (14) is connected to the outer ring plate (12), the other end of the U-shaped connecting rod (14) is connected to the inner ring plate (13), multiple U-shaped connecting rods (14) are distributed between the outer ring plate (12) and the inner ring plate (13), the outer ring plate (12) and the inner ring plate (13) have the same axis, and both the outer ring plate (12) and the inner ring plate (13) are inserted into the inner cavity (02) of the reagent kit.

2. The plasmin-α2 plasmin inhibitor complex assay kit according to claim 1, characterized in that... The outer side of the outer ring plate (12) is in contact with the outer side of the inner cavity (02) of the reagent kit, and the inner side of the inner ring plate (13) is in contact with the inner side of the inner cavity (02) of the reagent kit. The lower part of the vertical connecting rod (15) is connected to the outer ring plate (12), and the side of the vertical connecting rod (15) is connected to the ring limiting rod (16). A set of ring limiting rods (16) are distributed on the side of the vertical connecting rod (15), and multiple vertical connecting rods (15) are evenly distributed on the outer ring plate (12).

3. The plasmin-α2 plasmin inhibitor complex assay kit according to claim 2, characterized in that... The container (03) has an arc-shaped clearance hole (10) on its side. The support plate (07) is connected to the side fixing plate (20). The side fixing plate (20) is connected to the circular reagent kit (01). The rotating toothed disk (08) is in contact with the support plate (07). The lower part of the rotating toothed disk (08) has a toothed disk lower column (09). The toothed disk lower column (09) is inserted into the support plate (07). The toothed disk lower column (09) rotates in the support plate (07). The rotating vertical rod (05) passes through the support plate (07) and is connected to the rotating toothed disk (08). The upper part of the rotating vertical rod (05) is connected to the rotating handle (06).

4. The plasmin-α2 plasmin inhibitor complex assay kit according to claim 3, characterized in that... The rotating toothed disk (08) is inserted into the arc-shaped relief hole (10), and the rotating toothed disk (08) meshes with the inner side of the inner annular support plate (13). The upper surfaces of the two sets of spheres (18) are respectively attached to the bottom surfaces of the outer annular support plate (12) and the inner annular support plate (13). The reagent tube (19) is inserted into the annular limiting rod (16), and the lower surface of the reagent tube (19) is attached to the outer annular support plate (12) and the inner annular support plate (13).

5. The plasmin-α2 plasmin inhibitor complex assay kit according to claim 1, characterized in that... The lower part of the support platform (17) is connected to the circular reagent kit (01), the upper surface of the support platform (17) is in contact with the lower surface of the reagent tube (19), and the upper part of the reagent tube (19) passes through the support plate (07).

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