An immune cell centrifugation device

By designing a stable frame and clamping block structure in the immune cell centrifugation device, combined with a servo motor and transmission mechanism, the problem of test tubes sliding or being thrown out during centrifugation was solved, achieving stable fixation of the test tubes and improving the safety and effectiveness of the equipment.

CN224486301UActive Publication Date: 2026-07-14SHANGHAI DENDREON BIO-PHARM TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI DENDREON BIO-PHARM TECH CO LTD
Filing Date
2025-06-09
Publication Date
2026-07-14

AI Technical Summary

Technical Problem

Existing immune cell centrifugation devices are prone to the test tubes slipping or being thrown out during centrifugation, affecting the safety and effectiveness of the equipment.

Method used

An immune cell centrifugation device was designed, comprising a box, partition, placement base plate, threaded rotating rod, stabilizing frame, sliding plate, clamping block, and transmission mechanism. The test tubes are stably fixed by multi-point clamping of the stabilizing frame and clamping block, combined with servo motor and transmission mechanism.

Benefits of technology

It effectively improves the stability of test tubes during centrifugation, prevents test tubes from detaching or flying out, and enhances the safety and effectiveness of the equipment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to an immune cell centrifugal device, including box and test tube, the inside wall lower part of box is fixedly connected with the partition, both sides of the partition top are provided with the placement bottom plate, each placement bottom plate top is fixedly connected with the threaded rotating lever, each threaded rotating lever middle part is slidably connected with the adjusting plate, each placement bottom plate top is provided with a plurality of no.
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Description

Technical Field

[0001] This utility model relates to the field of cell processing equipment technology, specifically to an immune cell centrifugation device. Background Technology

[0002] Cell separation techniques include centrifugation, flow cytometry, and cell electrophoresis. Centrifugation is a fundamental method for studying cell nuclei, mitochondria, Golgi apparatus, lysosomes, microbodies, and various macromolecules, including differential centrifugation and density gradient centrifugation.

[0003] Referring to a patent for an immune cell centrifugation device (publication number: CN214974886U), the device consists of a first centrifuge plate, a first centrifuge base plate, a second centrifuge plate, and a second centrifuge base plate, all of which are fixedly connected to a centrifuge shaft. The first and second centrifuge plates are provided with through holes, and the first and second centrifuge base plates are provided with grooves to increase the number of test tubes that can be placed in a single centrifugation cycle and accelerate centrifugation efficiency. However, the device directly inserts the test tubes into the through holes without any protective measures, which makes it easy for the test tubes to slide upwards or even be thrown out during centrifugation, affecting the safety and effectiveness of the device.

[0004] Therefore, an immune cell centrifugation device is proposed to solve the above problems. Utility Model Content

[0005] The technical solution adopted by this utility model to solve the technical problem is: an immune cell centrifugation device, including a box and test tubes. A partition is fixedly connected to the lower middle part of the inner wall of the box. Placement base plates are provided on both sides of the top of the partition. A threaded rotating rod is fixedly connected to the top of each placement base plate. An adjusting plate is slidably connected to the middle of each threaded rotating rod. A plurality of first-order stabilizing frames are provided on the top of each placement base plate. A plurality of second-order stabilizing frames are provided at the bottom of each placement base plate. A perforation is provided on each placement base plate at the position corresponding to each second-order stabilizing frame.

[0006] As a preferred technical solution of this utility model, a servo motor is fixedly connected to the bottom of the inner wall of the box, and a first rotating rod is fixedly connected to the output end of the servo motor. The first rotating rod passes through the partition and is fixedly connected to the corresponding placement base plate. A second rotating rod is rotatably connected to the bottom of the inner wall of the box away from the servo motor. The second rotating rod passes through the partition and is fixedly connected to the corresponding placement base plate. A transmission mechanism is provided between the first rotating rod and the second rotating rod.

[0007] As a preferred technical solution of this utility model, a sliding plate is slidably connected to both sides of the inner wall of the first stabilizing frame, and a clamping block is fixedly connected to one side of each of the two sliding plates that are close to each other. A protective pad is fixedly connected to the arc-shaped groove of each of the two clamping blocks, and several springs are fixedly connected between each sliding plate and the inner wall of the first stabilizing frame.

[0008] As a preferred technical solution of this utility model, the inner walls of the second stabilizing frame are slidably connected to the second sliding plate on both sides. The two second sliding plates are fixedly connected to the clamping block on the side close to each other. The two second sliding plates are fixedly connected to the middle of the side far apart from each other. The two sides of the second stabilizing frame are threadedly connected to the adjusting screw. Each adjusting screw passes through the second stabilizing frame and is rotatably connected to the corresponding limiting block.

[0009] As a preferred embodiment of this utility model, the transmission mechanism includes a first rotating wheel, a second rotating wheel, and a transmission belt. The transmission belt is disposed between the first rotating wheel and the second rotating wheel. The first rotating wheel is fixedly connected to a first rotating rod, and the second rotating wheel is fixedly connected to a second rotating rod.

[0010] As a preferred embodiment of this utility model, each of the adjusting plates is provided with an upper locking plate and a lower locking plate above and below, and each of the upper locking plate and the lower locking plate is threadedly connected to the corresponding threaded rotating rod.

[0011] This utility model has the following advantages: The first stabilizing frame, its internal spring, the first sliding plate, and the clamping block effectively clamp and limit the bottom of the test tube. The second stabilizing frame, its upper adjusting screw, limiting block, the second transmission plate, and the clamping block effectively clamp and fix the middle or top of the test tube. The cooperation of the two sets of clamping blocks effectively ensures the stability of the test tube during centrifugation. The protective gasket increases the friction between the clamping block and the test tube, further improving clamping stability. The adjusting plate allows for free adjustment according to test tubes of different lengths, adapting to the stable position of test tubes of different lengths, effectively ensuring the effectiveness and safety of the equipment. Attached Figure Description

[0012] Figure 1 This is a cross-sectional structural schematic diagram of a preferred embodiment of the present invention;

[0013] Figure 2 This is a top view cross-sectional structural diagram of the first stabilizing frame according to a preferred embodiment of the present invention;

[0014] Figure 3 This is a top view cross-sectional view of the second stabilizing frame according to a preferred embodiment of the present invention;

[0015] Figure 4 This is a schematic diagram of the transmission mechanism structure of a preferred embodiment of the present invention.

[0016] Explanation of reference numerals in the attached drawings: 1. Box body; 2. Partition plate; 3. Placement base plate; 4. Threaded rotating rod; 5. Adjusting plate; 6. Test tube; 7. First stabilizing frame; 8. Second stabilizing frame; 9. Servo motor; 10. First rotating rod; 11. Second rotating rod; 12. Transmission mechanism; 121. First rotating wheel; 122. Second rotating wheel; 123. Transmission belt; 13. Upper locking plate; 14. Lower locking plate; 15. First sliding plate; 16. Clamping block; 17. Protective pad; 18. Spring; 19. Second sliding plate; 20. Adjusting screw; 21. Limiting block. Detailed Implementation

[0017] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0018] The present invention will be further described below with reference to the accompanying drawings. Example

[0019] Please refer to the following: Figure 1-4 This utility model discloses an immune cell centrifugation device, comprising a box body 1 and test tubes 6. A partition 2 is fixedly connected to the lower part of the inner wall of the box body 1. A placement base plate 3 is provided on both sides of the top of the partition 2. A threaded rotating rod 4 is fixedly connected to the top of each placement base plate 3. An adjusting plate 5 is slidably connected to the middle of each threaded rotating rod 4. An upper locking plate 13 and a lower locking plate 14 are respectively provided above and below each adjusting plate 5. Each upper locking plate 13 and lower locking plate 14 are threadedly connected to the corresponding threaded rotating rod 4. A number of first-order stabilizing frames 7 are provided on the top of each placement base plate 3. A number of second-order stabilizing frames 8 are provided on the bottom of each placement base plate 3. A perforation is provided on each placement base plate 3 at the position corresponding to each second-order stabilizing frame 8.

[0020] A servo motor 9 is fixedly connected to the bottom of the inner wall of the housing 1. A first rotating rod 10 is fixedly connected to the output end of the servo motor 9. The first rotating rod 10 passes through the partition 2 and is fixedly connected to the corresponding placement base plate 3. A second rotating rod 11 is rotatably connected to the bottom of the inner wall of the housing 1 away from the servo motor 9. The second rotating rod 11 passes through the partition 2 and is fixedly connected to the corresponding placement base plate 3. A transmission mechanism 12 is provided between the first rotating rod 10 and the second rotating rod 11. The transmission mechanism 12 includes a first rotating wheel 121, a second rotating wheel 122 and a transmission belt 123. The transmission belt 123 is provided between the first rotating wheel 121 and the second rotating wheel 122. The first rotating wheel 121 is fixedly connected to the first rotating rod 10 and the second rotating wheel 122 is fixedly connected to the second rotating rod 11.

[0021] Among them, the inner walls of the first stabilizing frame 7 are slidably connected to the first sliding plate 15 on both sides. The two first sliding plates 15 are fixedly connected to the clamping block 16 on the side close to each other. The arc grooves of the two clamping blocks 16 are fixedly connected to the protective pads 17. Several springs 18 are fixedly connected between each first sliding plate 15 and the inner wall of the first stabilizing frame 7.

[0022] Among them, the inner walls of the second stabilizing frame 8 are slidably connected to the second sliding plate 19 on both sides. The two second sliding plates 19 are fixedly connected to the clamping block 16 on the side close to each other. The two second sliding plates 19 are fixedly connected to the middle of the side far apart from each other. The two sides of the second stabilizing frame 8 are threadedly connected to the adjusting screw 20. Each adjusting screw 20 passes through the second stabilizing frame 8 and is rotatably connected to the corresponding limiting block 21.

[0023] Specifically, when using this utility model, the test tube 6 is passed through the perforation at the top of the adjustment plate 5 and the corresponding second stabilizing frame 8, and its end is inserted into the corresponding first stabilizing frame 7. Then, the adjustment plate 5 is adjusted to a suitable height according to the length of the test tube 6, and the adjustment plate 5 is fixed by screwing on the upper locking plate 13 and the lower locking plate 14. Then, by screwing on each adjusting screw 20, each second sliding plate 19 moves toward the test tube 6, so that the clamping block 16 clamps and limits the test tube 6. At the same time, the spring 18 in each first stabilizing frame 7 pushes the corresponding first sliding plate 15 to move, so that the corresponding clamping block 16 clamps and stabilizes the bottom end of the corresponding test tube 6, effectively ensuring the stability of the test tube and preventing it from flying out during equipment operation.

[0024] The above are merely preferred embodiments of this utility model. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principle of this utility model, and these improvements and modifications should also be considered within the scope of protection of this utility model.

Claims

1. An immune cell centrifugation device, comprising a housing (1) and test tubes (6), characterized in that, A partition (2) is fixedly connected to the lower part of the inner wall of the box (1). A placement base plate (3) is provided on both sides of the top of the partition (2). A threaded rotating rod (4) is fixedly connected to the top of each placement base plate (3). An adjusting plate (5) is slidably connected to the middle of each threaded rotating rod (4). Several first-order stabilizing frames (7) are provided on the top of each placement base plate (3). Several second-order stabilizing frames (8) are provided at the bottom of each placement base plate (3). A through hole is provided on each placement base plate (3) at the position corresponding to each second-order stabilizing frame (8).

2. The immune cell centrifugation device as described in claim 1, characterized in that, A servo motor (9) is fixedly connected to the bottom of the inner wall of the box (1). A first rotating rod (10) is fixedly connected to the output end of the servo motor (9). The first rotating rod (10) passes through the partition (2) and is fixedly connected to the corresponding placement base plate (3). A second rotating rod (11) is rotatably connected to the bottom of the inner wall of the box (1) away from the servo motor (9). The second rotating rod (11) passes through the partition (2) and is fixedly connected to the corresponding placement base plate (3). A transmission mechanism (12) is provided between the first rotating rod (10) and the second rotating rod (11).

3. The immune cell centrifugation device as described in claim 1, characterized in that, Both sides of the inner wall of the first stabilizing frame (7) are slidably connected to a first sliding plate (15). The two first sliding plates (15) are fixedly connected to a clamping block (16) on the side close to each other. The two clamping blocks (16) are fixedly connected to a protective pad (17) in the arc groove. Several springs (18) are fixedly connected between each first sliding plate (15) and the inner wall of the first stabilizing frame (7).

4. The immune cell centrifugation device as described in claim 1, characterized in that, The inner walls of the second stabilizing frame (8) are slidably connected to the second sliding plate (19) on both sides. The two second sliding plates (19) are fixedly connected to the clamping block (16) on the side close to each other. The two second sliding plates (19) are fixedly connected to the middle of the side far apart from each other. The two sides of the second stabilizing frame (8) are threadedly connected to the adjusting screw (20). Each adjusting screw (20) passes through the second stabilizing frame (8) and is rotatably connected to the corresponding limiting block (21).

5. An immune cell centrifugation device as described in claim 2, characterized in that, The transmission mechanism (12) includes a first rotating wheel (121), a second rotating wheel (122), and a transmission belt (123). The transmission belt (123) is disposed between the first rotating wheel (121) and the second rotating wheel (122). The first rotating wheel (121) is fixedly connected to the first rotating rod (10), and the second rotating wheel (122) is fixedly connected to the second rotating rod (11).

6. An immune cell centrifugation device as described in claim 1, characterized in that, Each of the adjustment plates (5) is provided with an upper locking plate (13) and a lower locking plate (14) above and below, respectively, and each of the upper locking plate (13) and the lower locking plate (14) is threadedly connected to the corresponding threaded rotating rod (4).