A pharmaceutical granule wet granulation device

Abstract

The utility model discloses a medicine granule wet granulation device, including pelletizer and filter box, one side of pelletizer is fixed communication through the discharge pipe with the top of filter box, the inside of filter box is equipped with filter mechanism, including: filter assembly in filter mechanism, including the support seat of installation in the top of filter box, the inside slidingly connected with sliding plate of support seat, the utility model relates to medicine processing technical field. The medicine granule wet granulation device sets up filter mechanism, utilizes the drive motor to drive to make two groups of filter plates synchronous reciprocating sliding, realizes the shaking operation, can improve the filtering efficiency of filter plate to this, and can screen out the medicine granule that meets the standard through coarse filter plate and fine filter plate, avoids the admixture or medicine powder mixing, still needs the subsequent manual sorting, improves the work efficiency, also is convenient for the secondary recycling of medicine.

Description

Technical Field

[0001] This utility model relates to the field of drug processing technology, specifically to a wet granulation device for drug particles. Background Technology

[0002] The reference patent title is: A high-quality drug granule granulation device (Authorization Announcement No.: CN209286170U, Authorization Announcement Date: 2019.08.23), which includes a granulation device and a drying device, connected by a conveying pipe; the granulation device includes a drive base and a granulation box; the granulation box includes a chassis, a housing is provided above the chassis, a discharge port is provided on one side of the housing, and a stirring top cover is provided on the top of the housing; the drying device includes a drying cylinder, one end of which is connected to The device includes a cyclone fan and a dehumidifier connected to the other end; a feed inlet is located at the top of one end of the drying cylinder; the dehumidifier includes a dehumidification cylinder connected to the drying cylinder, with exhaust sieve holes on the dehumidification cylinder and an exhaust fan outside the dehumidification cylinder; one end of the conveying pipe is connected to the discharge port, and the other end of the conveying pipe is connected to the feed inlet. This device has good granulation and drying effects, and the produced granules have uniform particle size, which not only meets the requirements of wet granulation, but also improves the efficiency of wet granulation for preparing drug granules and enhances the quality of the produced granules.

[0003] Based on the above-mentioned documents, wet granulation machines are used to process moist powder into the required granules, and can also crush lumpy dry materials into the required granules. The mechanical transmission system is completely enclosed in the machine body, and the whole machine operates smoothly. Since the surface of the drug granules will carry more or less drug powder when they are output from the discharge pipe, too much drug powder will easily cause poor sealing when the drug granules enter the packaging. The above-mentioned device can filter and separate the drug powder from the drug granules by setting up a screen, thereby improving the quality of the drug. However, the filtration structure is relatively simple. During the drug granule processing, there are some defective products that are too large and do not meet the standards. A simple set of screens cannot screen them, and they will be mixed in with the finished drug granules, affecting the quality of the drug. In addition, the screens in the above-mentioned device are fixedly installed in the discharge pipe, which is prone to blockage and is not easy to disassemble and clean. Therefore, this utility model provides a wet granulation device for drug granules. Utility Model Content

[0004] To address the shortcomings of existing technologies, this utility model provides a wet granulation device for pharmaceutical particles, which solves the problems of simple filtration structures, poor filtration quality, and easy impact on the quality of pharmaceutical particles in existing wet granulation devices, as well as the problems of easy clogging and inconvenience in disassembly and cleaning of existing filtration structures.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a wet granulation device for pharmaceutical granules, comprising a granulator and a filter box, wherein one side of the granulator is fixedly connected to the top of the filter box via a discharge pipe, and the filter box contains a filtration mechanism, which includes:

[0006] A filter assembly includes a support base mounted on top of a filter box, a sliding plate slidably connected inside the support base, a symmetrical linkage plate fixedly connected to the bottom of the sliding plate, connecting plates fixedly connected to both ends of the sliding plate, a connecting rod fixedly connected to the surface of the connecting plate, one end of the connecting rod extending through into the interior of the filter box, and a filter plate fixedly connected to one end of the connecting rod via a mounting assembly.

[0007] The drive assembly, located at the top of the filter box, is used to drive the sliding plate to reciprocate.

[0008] Preferably, the drive assembly includes a drive motor mounted on the top of the filter box, and one end of the output shaft of the drive motor is fixedly connected to an eccentric wheel via a coupling, the surface of the eccentric wheel being in contact with the inner wall of the linkage plate.

[0009] Preferably, the mounting assembly includes a mounting plate mounted on one end of a connecting rod. The mounting plate has a mounting groove on its inner side. A limiting plate is fixedly connected to the outer side of the mounting plate. A limiting rod is slidably connected inside the limiting plate. The bottom end of the limiting rod is fixedly connected to the bottom of the inner cavity of the limiting plate via a limiting spring. A pull plate is fixedly connected to the top end of the limiting rod. A symmetrical mounting rod is fixedly connected to the bottom of the pull plate. One end of the mounting rod extends through into the inner cavity of the mounting groove.

[0010] Preferably, symmetrical assembly plates are fixedly connected to both sides of the filter plate, the surface of the assembly plate is slidably connected to the inner surface of the mounting groove, the top of the assembly plate is provided with an assembly groove, and the inner surface of the assembly groove is engaged with one end of the mounting rod.

[0011] Preferably, the filter plates are provided in two sets, namely a coarse filter plate and a fine filter plate.

[0012] Preferably, a collection drawer is installed at the bottom of the filter box cavity, and a discharge plate is fixedly connected to the inner wall of the filter box.

[0013] Beneficial effects

[0014] This invention provides a wet granulation apparatus for pharmaceutical particles. Compared with the prior art, it has the following advantages:

[0015] 1. This wet granulation device for pharmaceutical granules uses a drive motor to rotate an eccentric wheel. The rotation of the eccentric wheel causes the adjacent linkage plate to slide back and forth synchronously. The sliding of the linkage plate causes the sliding plate, connecting plate, connecting rod, mounting components, and two sets of filter plates to slide back and forth synchronously, causing the two sets of filter plates to vibrate. At this time, the pharmaceutical granules first fall into the coarse filter plate. After being filtered by the coarse filter plate, the pharmaceutical granules that do not meet the standard are discharged through the discharge plate on one side. Pharmaceutical granules that meet the standard size will be mixed with the powder and fall onto the surface of the fine filter plate. At this time, they are filtered again by the fine filter plate, and the pharmaceutical granules that meet the standard are discharged through the discharge plate on one side for collection. By setting up a filtration mechanism and using the drive motor to make the two sets of filter plates slide back and forth synchronously to achieve the vibration operation, the filtration efficiency of the filter plates can be improved. The coarse and fine filter plates can screen out pharmaceutical granules that meet the standard, avoiding the mixing of impurities or powder and the need for subsequent manual sorting. This improves work efficiency and facilitates the secondary recycling of pharmaceuticals.

[0016] 2. This wet granulation device for pharmaceutical granules allows the installation rod and the limiting rod to slide upwards synchronously by pulling the pull plate upwards. This causes the limiting rod to slide inside the limiting plate, stretching the limiting spring and causing the installation rod to slide out of the assembly slot. Then, by directly pulling the filter plate, the assembly plate slides out of the installation slot, thus achieving rapid disassembly of the filter plate. With the installation components, the filter plate can be quickly installed and disassembled, improving work efficiency and facilitating the inspection and cleaning of the filter plate. Attached Figure Description

[0017] Figure 1 This is a three-dimensional schematic diagram of the external structure of this utility model;

[0018] Figure 2 This is a schematic diagram of the external structure of the filter box of this utility model;

[0019] Figure 3 This is a schematic diagram of the internal structure of the filter box of this utility model;

[0020] Figure 4 This is a three-dimensional schematic diagram of the filter assembly of this utility model;

[0021] Figure 5 This is an exploded structural diagram of the mounting component of this utility model.

[0022] In the diagram: 1-Pelletizer, 2-Filter box, 3-Discharge pipe, 4-Filtering mechanism, 41-Filter assembly, 411-Support base, 412-Sliding plate, 413-Linkage plate, 414-Connecting plate, 415-Connecting rod, 416-Filter plate, 42-Drive assembly, 421-Drive motor, 422-Eccentric wheel, 5-Mounting assembly, 51-Mounting plate, 52-Mounting groove, 53-Limiting plate, 54-Limiting rod, 55-Limiting spring, 56-Pull plate, 57-Mounting rod, 6-Assembly plate, 7-Assembly groove, 8-Collection drawer, 9-Discharge plate. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figure 1-5 This utility model provides a technical solution:

[0025] A wet granulation apparatus for pharmaceutical granules includes a granulator 1 and a filter box 2. One side of the granulator 1 is fixedly connected to the top of the filter box 2 via a discharge pipe 3. The filter box 2 is equipped with a filtration mechanism 4, which includes:

[0026] The filter assembly 41 includes a support base 411 mounted on the top of the filter box 2. A sliding plate 412 is slidably connected inside the support base 411. A symmetrical linkage plate 413 is fixedly connected to the bottom of the sliding plate 412. A connecting plate 414 is fixedly connected to both ends of the sliding plate 412. A connecting rod 415 is fixedly connected to the surface of the connecting plate 414. One end of the connecting rod 415 extends through into the interior of the filter box 2. A filter plate 416 is fixedly connected to one end of the connecting rod 415 through the mounting assembly 5.

[0027] The drive assembly 42 is located on the top of the filter box 2 and is used to drive the sliding plate 412 to slide back and forth.

[0028] A granulator is a device used to make materials into granules. It is widely used in pharmaceutical, chemical, and food industries. It can grind moist powder raw materials into granules, make raw materials into granules, and crush dry materials that have agglomerated into lumps.

[0029] The support base 411 is used to limit the sliding of the sliding plate 412.

[0030] In this embodiment, the drive assembly 42 includes a drive motor 421 installed on the top of the filter box 2. One end of the output shaft of the drive motor 421 is fixedly connected to an eccentric wheel 422 via a coupling. The surface of the eccentric wheel 422 is in contact with the inner wall of the linkage plate 413.

[0031] The drive motor 421 is a three-phase asynchronous motor and is connected to an external circuit via wires.

[0032] With the filter mechanism 4 in place, the two sets of filter plates 416 are driven by the drive motor 421 to slide back and forth synchronously, achieving a shaking operation. This improves the filtration efficiency of the filter plates 416. The coarse and fine filter plates can screen out drug particles that meet the standards, avoiding the mixing of impurities or drug powder, which would otherwise require manual sorting. This improves work efficiency and facilitates the secondary recycling of drugs.

[0033] In this embodiment, the mounting assembly 5 includes a mounting plate 51 mounted on one end of the connecting rod 415. The inner side of the mounting plate 51 is provided with a mounting groove 52. A limiting plate 53 is fixedly connected to the outer side of the mounting plate 51. A limiting rod 54 is slidably connected inside the limiting plate 53. The bottom end of the limiting rod 54 is fixedly connected to the bottom of the inner cavity of the limiting plate 53 through a limiting spring 55. A pull plate 56 is fixedly connected to the top end of the limiting rod 54. A symmetrical mounting rod 57 is fixedly connected to the bottom of the pull plate 56. One end of the mounting rod 57 extends through into the inner cavity of the mounting groove 52.

[0034] Under the influence of the elasticity of the limit spring 55, one end of the mounting rod 57 will always remain engaged with the inner surface of the mounting groove 7.

[0035] In this embodiment, symmetrical assembly plates 6 are fixedly connected to both sides of the filter plate 416. The surface of the assembly plate 6 is slidably connected to the inner surface of the mounting groove 52. An assembly groove 7 is provided on the top of the assembly plate 6. The inner surface of the assembly groove 7 is engaged with one end of the mounting rod 57.

[0036] In this embodiment, two sets of filter plates 416 are provided, namely a coarse filter plate and a fine filter plate.

[0037] The coarse filter plate is positioned above the fine filter plate.

[0038] In this embodiment, a collection drawer 8 is installed at the bottom of the inner cavity of the filter box 2, and a discharge plate 9 is fixedly connected to the inner wall of the filter box 2.

[0039] Drawer 8 is used to collect medicine powder for easy recycling.

[0040] With the installation component 5, the filter plate 416 can be quickly installed and removed, which improves work efficiency and facilitates the inspection and cleaning of the filter plate 416.

[0041] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

[0042] During operation, after the granulator 1 completes the drug production, the drug granules enter the filter box 2 through the discharge pipe 3. At this time, the drive motor 421 is started to drive the eccentric wheel 422 to rotate. The rotation of the eccentric wheel 422 causes the linkage plate 413, which is in contact with it, to slide back and forth synchronously. The sliding of the linkage plate 413 causes the sliding plate 412, connecting plate 414, connecting rod 415, mounting assembly 5, and two sets of filter plates 416 to slide back and forth synchronously, causing the two sets of filter plates 416 to start shaking. At this time, the drug granules will first fall into the interior of the coarse filter plate. After being filtered by the coarse filter plate, the drug granules that do not meet the standard will be discharged through the discharge plate 9 on one side, while the drug granules that meet the standard size will be mixed in. When the medicine powder falls onto the surface of the fine filter plate, it is filtered again by the fine filter plate. The medicine particles that meet the standards will be discharged through the discharge plate 9 on one side and collected, while the medicine powder will fall into the collection drawer 8 for centralized collection. After the operation, the maintenance door on one side of the filter box 2 is opened. Then, by pulling the pull plate 56 upward, the mounting rod 57 and the limiting rod 54 slide upward simultaneously, so that the limiting rod 54 slides inside the limiting plate 53, which stretches the limiting spring 55 and causes the mounting rod 57 to slide out of the assembly groove 7. Then, by directly pulling the filter plate 416, the assembly plate 6 slides out of the mounting groove 52, thereby realizing the quick disassembly of the filter plate 416, which is convenient for subsequent maintenance and cleaning operations.

[0043] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0044] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A wet granulation apparatus for pharmaceutical particles, comprising a granulator (1) and a filter box (2), characterized in that: One side of the granulator (1) is fixedly connected to the top of the filter box (2) via a discharge pipe (3). The filter box (2) is equipped with a filter mechanism (4), which includes: The filter assembly (41) includes a support base (411) installed on the top of the filter box (2), a sliding plate (412) is slidably connected inside the support base (411), a symmetrical linkage plate (413) is fixedly connected to the bottom of the sliding plate (412), a connecting plate (414) is fixedly connected to both ends of the sliding plate (412), a connecting rod (415) is fixedly connected to the surface of the connecting plate (414), one end of the connecting rod (415) extends through into the interior of the filter box (2), and one end of the connecting rod (415) is fixedly connected to the filter plate (416) through the mounting assembly (5); The drive assembly (42) is located on top of the filter box (2) and is used to drive the sliding plate (412) to slide back and forth.

2. The wet granulation apparatus for pharmaceutical particles according to claim 1, characterized in that: The drive assembly (42) includes a drive motor (421) installed on the top of the filter box (2). One end of the output shaft of the drive motor (421) is fixedly connected to an eccentric wheel (422) via a coupling. The surface of the eccentric wheel (422) is in contact with the inner wall of the linkage plate (413).

3. The wet granulation apparatus for pharmaceutical particles according to claim 1, characterized in that: The mounting assembly (5) includes a mounting plate (51) mounted on one end of a connecting rod (415). The mounting plate (51) has an mounting groove (52) on its inner side. A limiting plate (53) is fixedly connected to the outer side of the mounting plate (51). A limiting rod (54) is slidably connected inside the limiting plate (53). The bottom end of the limiting rod (54) is fixedly connected to the bottom of the inner cavity of the limiting plate (53) through a limiting spring (55). A pull plate (56) is fixedly connected to the top end of the limiting rod (54). A symmetrical mounting rod (57) is fixedly connected to the bottom of the pull plate (56). One end of the mounting rod (57) extends through into the inner cavity of the mounting groove (52).

4. The wet granulation apparatus for pharmaceutical particles according to claim 3, characterized in that: The filter plate (416) is fixedly connected to two symmetrical assembly plates (6). The surface of the assembly plate (6) is slidably connected to the inner surface of the mounting groove (52). The top of the assembly plate (6) is provided with an assembly groove (7). The inner surface of the assembly groove (7) is engaged with one end of the mounting rod (57).

5. The wet granulation apparatus for pharmaceutical particles according to claim 1, characterized in that: The filter plate (416) is provided in two sets, and the filter plate (416) is divided into a coarse filter plate and a fine filter plate.

6. The wet granulation apparatus for pharmaceutical particles according to claim 1, characterized in that: A collection drawer (8) is installed at the bottom of the inner cavity of the filter box (2), and a discharge plate (9) is fixedly connected to the inner wall of the filter box (2).

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