A rapid plate washer for cell engineering

Abstract

This utility model relates to the field of cell engineering technology, specifically a rapid plate washing machine for cell engineering. A rotating block is rotatably installed in a groove at the top of the housing, and microplates are vertically fixed in slots on both radial sides. A rotating shaft passes through the groove and connects to a rotating motor to achieve dual-station switching. In the telescopic groove on the side wall of the groove, a telescopic plate moves horizontally through an internal threaded cylinder and a guide rod. A flow divider plate at the end is equipped with spray needles. A drive motor drives a threaded rod to insert the spray needles parallel into the holes of the microplate. A first suction pump is connected to a suction connector to pump cleaning liquid to the flow divider plate. A second suction pump passes through the groove and connects to a discharge connector to pump out waste liquid. A touch screen, in conjunction with a circuit board, coordinates the rotating motor to drive the microplate to centrifuge and dry the residual liquid. The two suction pumps operate synchronously. This equipment improves efficiency through continuous cleaning at dual stations and synchronous centrifugal drying. The horizontal insertion structure of the spray needles ensures the cleaning accuracy inside the holes, and the closed-loop waste liquid recovery system avoids cross-contamination.

Description

Technical Field

[0001] This utility model relates to the field of cell engineering technology, specifically a rapid plate washing machine for cell engineering. Background Technology

[0002] The rapid plate washer for cell engineering is an automated laboratory device specifically designed for the efficient cleaning of microplates used in cell culture or assays. It uses a mechanically driven system to precisely inject cleaning solution through a spray needle, while simultaneously employing a suction device to quickly remove waste liquid. This allows for thorough cleaning of multi-well plates in a short time. Its necessity lies in the fact that cell engineering experiments often involve high-throughput microplate handling (such as ELISA and cytotoxicity assays). Traditional manual cleaning is not only time-consuming and labor-intensive, but also prone to cross-contamination or residue interference due to inconsistent procedures, directly affecting the reliability of experimental results. The rapid plate washer, through a standardized process, achieves both improved cleaning efficiency and cleanliness, making it a key tool for ensuring the accuracy and reproducibility of cell experiment data.

[0003] However, traditional plate washing machines only support single-plate sequential processing. Switching between micro-perforated plates requires manual intervention, resulting in low processing efficiency and poor operational continuity. Furthermore, the traditional vertical lifting structure of the spray needle occupies a large space and is prone to positioning deviation. Uneven coverage of the cleaning fluid may cause contamination between the holes, and the reliance on natural drainage of residual liquid also affects data reliability. Utility Model Content

[0004] The purpose of this invention is to provide a rapid plate washing machine for cell engineering to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] A rapid plate washing machine for cell engineering includes a housing. A groove is provided on one side of the top of the housing. A rotating block is rotatably installed in the groove. Slots are symmetrically installed on both radial sides of the rotating block. A rotating shaft is fixedly installed in the middle of the rotating block. The rotating shaft passes through the bottom of the groove and is located at the output end of a rotating motor. The rotating motor is installed inside the housing and perpendicular to the bottom of the groove by bolts.

[0007] Preferably, a telescopic groove extends from one side of the groove, and a telescopic plate is provided in the telescopic groove. A diverter plate is installed at one end of the telescopic plate by bolts, and a plurality of spray needles are fixedly installed at the opposite end of the diverter plate and the telescopic plate.

[0008] Preferably, an internally threaded cylinder is fixedly installed at the middle of one end opposite to the telescopic plate and the diverter plate, and guide rods are fixedly installed on the adjacent sides of the telescopic plate and the internally threaded cylinder, respectively. The other ends of the internally threaded cylinder and the guide rods are slidably installed in the guide block after passing through the telescopic groove.

[0009] Preferably, the guide block is fixedly installed inside the housing, and a threaded rod is installed inside the internal threaded cylinder by threads. The threaded rod is located at the output end of the drive motor, and the drive motor is installed inside the housing on the side adjacent to the guide block by bolts.

[0010] Preferably, a first suction pump and a second suction pump are respectively bolted to the side of the housing adjacent to the drive motor. The suction end of the first suction pump is connected to the suction connector after passing through the housing through a pipe, and the pumping end of the first suction pump is connected to the diverter plate after passing through the expansion groove through a pipe.

[0011] Preferably, the suction end of the second suction pump is connected to the groove through a pipe to form a through connection, and the pumping end of the second suction pump is connected to the discharge connector after passing through the box body through a pipe. The suction connector and the discharge connector are respectively fixedly installed on one side of the outside of the box body.

[0012] Preferably, a switch is installed through the box body on the opposite side of the suction connector and the discharge connector, a power cord is installed through the box body on the side adjacent to the switch, and a cover is installed on the top of the box body on the side adjacent to the groove via a hinge.

[0013] Preferably, a control box is fixedly installed on the top of the housing adjacent to the extension groove, a touch screen is fixedly installed on the top of the control box, and a circuit board is installed inside the control box by bolts.

[0014] Preferably, the corresponding pins of the circuit board, touch screen, switch, power cord, drive motor, rotary motor, first suction pump and second suction pump are connected by flexible wires.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] 1. This rapid plate washing machine for cell engineering, through a dual-slot rotating structure and a rotating motor drive, achieves continuous automatic washing and synchronous centrifugal drying of dual microplates, significantly improving batch processing efficiency and eliminating residual errors from manual operation.

[0017] 2. This rapid plate washer for cell engineering works in conjunction with a horizontal parallel displacement insertion mechanism of the spray needle and a closed-loop suction system to ensure precise injection of the cleaning solution and zero overflow of waste liquid, effectively avoiding cross-contamination between wells and ensuring the cleanliness of the experimental environment. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a schematic diagram of the left-side structure of this utility model;

[0020] Figure 3 This is a plan view of the box body of this utility model;

[0021] Figure 4 This is a plan view of the control box of this utility model;

[0022] Figure 5 This utility model Figure 1 Enlarged diagram of point A in the middle.

[0023] In the diagram: 101, housing; 102, groove; 103, rotating block; 104, slot; 105, rotating shaft; 106, rotating motor; 107, telescopic groove; 108, telescopic plate; 109, diverter plate; 110, spray needle; 111, internal threaded cylinder; 112, guide rod; 113, guide block; 114, threaded rod; 115, drive motor; 116, first suction pump; 117, second suction pump; 118, suction connector; 119, discharge connector; 120, switch; 121, power cord; 122, cover; 123, control box; 124, touch screen; 125, circuit board. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figures 1-4 As shown, this utility model provides a technical solution:

[0026] A rapid plate washing machine for cell engineering includes a housing 101. A groove 102 is formed on one side of the top of the housing 101. A rotating block 103 is rotatably installed in the groove 102. Slots 104 are symmetrically installed on both radial sides of the rotating block 103. A rotating shaft 105 is fixedly installed in the middle of the rotating block 103. The rotating shaft 105 passes through the bottom end of the groove 102 and is located at the output end of a rotating motor 106. The rotating motor 106 is installed inside the housing 101 by bolts and is perpendicular to the bottom of the groove 102.

[0027] The above solution allows for the support and integrated installation of the main equipment through the housing; the groove provides space for the rotating block; the rotating block enables the microplate to be carried and rotated; the slot allows for the vertical fixation of the microplate; the rotating shaft transmits rotational power; and the rotating motor provides rotational drive.

[0028] In this embodiment, preferably, a telescopic groove 107 extends from one side of the groove 102, and a telescopic plate 108 is provided in the telescopic groove 107. A diverter plate 109 is installed at one end of the telescopic plate 108 by bolts, and a plurality of spray needles 110 are fixedly installed at the opposite end of the diverter plate 109 and the telescopic plate 108.

[0029] The above scheme allows the telescopic plate to move linearly via the telescopic groove; it enables the horizontal displacement of the spray needle carrier via the telescopic plate; it allows for uniform distribution of the cleaning fluid via the flow divider; and it enables precise injection of the cleaning fluid into the microporous plate via the spray needle.

[0030] In this embodiment, preferably, an internally threaded cylinder 111 is fixedly installed at the middle of one end of the telescopic plate 108 and the diverter plate 109, and guide rods 112 are fixedly installed on the adjacent sides of the telescopic plate 108 and the internally threaded cylinder 111, respectively. The other ends of the internally threaded cylinder 111 and the guide rods 112 are slidably installed in the guide block 113 after passing through the telescopic groove 107.

[0031] The above scheme allows the rotational motion to be converted into linear propulsion via the internally threaded cylinder; the guide rod can limit the offset of the telescopic plate; and the guide block can provide a reference for the sliding trajectory.

[0032] In this embodiment, preferably, the guide block 113 is fixedly installed inside the housing 101, and a threaded rod 114 is installed inside the internal threaded cylinder 111 by threads. The threaded rod 114 is located at the output end of the drive motor 115, and the drive motor 115 is installed inside the housing 101 on the side adjacent to the guide block 113 by bolts.

[0033] The above scheme allows for the stability of the telescopic path through the guide block; the horizontal thrust through the threaded rod; and the telescopic power source through the drive motor.

[0034] In this embodiment, preferably, a first suction pump 116 and a second suction pump 117 are respectively installed on the side of the housing 101 adjacent to the drive motor 115 by bolts. The suction end of the first suction pump 116 is connected to the suction connector 118 after passing through the housing 101 through a pipe, and the pumping end of the first suction pump 116 is connected to the diverter plate 109 after passing through the expansion groove 107 through a pipe.

[0035] The above scheme enables the active supply of cleaning fluid via the first suction pump; it allows connection to an external storage device via the suction connector; and it allows the cleaning fluid to be transported to the diversion plate via a pipeline passing through the expansion joint.

[0036] In this embodiment, preferably, the suction end of the second suction pump 117 is connected to the groove 102 through a pipe and forms a through connection, and the pumping end of the second suction pump 117 is connected to the discharge connector 119 after passing through the box 101 through a pipe. The suction connector 118 and the discharge connector 119 are respectively fixedly installed on the outer side of the box 101.

[0037] The above scheme enables active pumping of waste liquid through a second suction pump; waste liquid flowing out of the microporous plate can be collected through a pipe connected to the groove; a waste liquid recovery container can be connected to the discharge connector; and cross-contamination between the cleaning fluid and the waste liquid can be avoided by separating the suction connector and the discharge connector.

[0038] In this embodiment, preferably, a switch 120 is installed through the box 101 on the opposite side of the suction connector 118 and the discharge connector 119, a power cord 121 is installed through the box 101 on the side adjacent to the switch 120, and a cover 122 is installed on the top of the box 101 on the side adjacent to the groove 102 via a hinge.

[0039] The above solution allows for the control of equipment startup and shutdown via a switch; access to external power via a power cord; and prevention of foreign objects from entering the operating area via a cover.

[0040] In this embodiment, preferably, a control box 123 is fixedly installed on the top of the box 101 adjacent to the side of the extension groove, a touch screen 124 is fixedly installed on the top of the control box 123, and a circuit board 125 is installed inside the control box 123 by bolts.

[0041] The above solution allows for the fixation of the touchscreen and protection of the circuit board via the control box; the touchscreen enables real-time monitoring of operating parameters and program setting; and the circuit board coordinates the transmission of electrical signals between various components.

[0042] In this embodiment, preferably, the corresponding pins of the circuit board 125, touch screen 124, switch 120, power cord 121, drive motor 115, rotary motor 106, first suction pump 116 and second suction pump 117 are connected by flexible wires.

[0043] The above solution ensures stable power and signal transmission by connecting the circuit board and the actuator with flexible wires; and the controlled coordination of the first and second suction pumps by the drive motor can achieve closed-loop management of the fully automated cleaning process.

[0044] In this embodiment, a rapid plate washer for cell engineering is used such that after the user starts the equipment via switch 120, the power cord 121 continuously provides power, enabling the entire electrical system to operate. At this time, the circuit board 125, touch screen 124, switch 120, power cord 121, drive motor 115, rotary motor 106, first suction pump 116, and second suction pump 117 are interconnected via flexible wires, forming a collaborative control system. The touch screen 124 provides real-time feedback of operating parameters, and the circuit board 125 automatically processes the command flow, reducing operational complexity and improving equipment reliability. When the user opens the cover 122, two microplates can be vertically inserted into the slots 104 on both radial sides of the rotating block 103. The vertical slots 104 are designed to ensure the microplates are properly seated. The perforated plate is stably loaded, while the dual-station structure maximizes batch processing efficiency. After setting the cleaning program via the touchscreen 124, the equipment first operates on the micro-perforated plate in the first slot 104: the drive motor 115 starts and drives the threaded rod 114 to rotate. Due to the meshing transmission between the internal threaded cylinder 111 and the threaded rod 114, and the guide rod 112 being restricted to linear sliding within the fixed guide block 113, the telescopic plate 108 is precisely pushed to a horizontally extended state. This movement simultaneously drives the bolt-fixed diverter plate 109 and its spray needle 110 to move in parallel, allowing the spray needle 110 to be directly and horizontally inserted into the micro-perforated plate hole, eliminating cross-contamination between holes caused by positional deviation. Immediately afterwards, the first suction pump 116 draws cleaning fluid from the suction connector 118 and pumps it through the pipeline. The liquid is pumped into the diversion plate 109, and finally injected into each hole of the microporous plate through the spray needle 110 to complete deep cleaning. At the same time, the waste liquid flows naturally into the lower groove 102, and the second suction pump 117 immediately draws it in through the through pipe and discharges it through the discharge connector 119, forming a closed-loop treatment system for cleaning and waste liquid, eliminating the risk of spillage and pollution. After the first microporous plate is cleaned, the drive motor 115 reverses to drive the threaded rod 114. Through the synergistic action of the internal threaded cylinder 111 and the guide rod 112, the telescopic plate 108 is pulled horizontally back to the initial position, ensuring that the spray needle 110 is completely withdrawn from the microporous plate hole and avoiding subsequent rotational interference. Then, the rotation motor 106 starts, driving the rotation shaft 105 to rotate 180 degrees, so that the second slot 104 is precisely positioned. The device is positioned at the operating station of the spray needle 110, while the first microplate is moved to the standby area. For the second microplate, the equipment completely replicates the cleaning process: the drive motor 115 drives the telescopic plate 108 to extend horizontally again, and the spray needle 110 is inserted parallel into the hole of the microplate. The first suction pump 116 injects cleaning fluid, and the second suction pump 117 simultaneously suctions waste liquid. The dual-plate continuous operation mode significantly improves the equipment's throughput efficiency. After both microplates have completed cleaning and waste liquid suction, the drive motor 115 retracts the telescopic plate 108 for the last time, so that the spray needle 110 is completely removed from the working area. Then, the rotating motor 106 drives the rotating block 103 to rotate at high speed. The microplates in the slots 104 on both sides are subjected to centrifugal force, and the residual liquid is thrown into the groove 102.During this process, the second suction pump 117 operates continuously, rapidly and completely draining the waste liquid. The combined effect of centrifugal force and active suction ensures that the residue removal rate inside the wells exceeds the limits of traditional manual methods. After the procedure is completed, the user can remove the clean microplate. The groove 102 throughout the process serves as a temporary storage pool for waste liquid, forming a splash-proof barrier with the second suction pump 117. The cap 122 prevents external contaminants from entering, providing a high level of cleanliness for cell engineering experiments.

[0045] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A rapid plate washer for cell engineering, comprising a housing (101), characterized in that: A groove (102) is provided on one side of the top of the box (101). A rotating block (103) is rotatably installed in the groove (102). Slots (104) are symmetrically installed on both sides of the rotating block (103). A rotating shaft (105) is fixedly installed in the middle of the rotating block (103). The rotating shaft (105) passes through the bottom end of the groove (102) and is located at the output end of the rotating motor (106). The rotating motor (106) is installed inside the box (101) by bolts and is perpendicular to the bottom of the groove (102).

2. The rapid plate washer for cell engineering according to claim 1, characterized in that: A telescopic groove (107) extends from one side of the groove (102), and a telescopic plate (108) is provided in the telescopic groove (107). A diverter plate (109) is installed at one end of the telescopic plate (108) by bolts. Several spray needles (110) are fixedly installed at the opposite end of the diverter plate (109) and the telescopic plate (108).

3. The rapid plate washer for cell engineering according to claim 2, characterized in that: An internal threaded cylinder (111) is fixedly installed at the middle of one end opposite to the telescopic plate (108) and the diverter plate (109). Guide rods (112) are fixedly installed on the adjacent sides of the telescopic plate (108) and the internal threaded cylinder (111). The other ends of the internal threaded cylinder (111) and the guide rods (112) pass through the telescopic groove (107) and are slidably installed in the guide block (113).

4. A rapid plate washer for cell engineering according to claim 3, characterized in that: The guide block (113) is fixedly installed inside the housing (101). The threaded rod (114) is installed inside the internal threaded cylinder (111) by threads. The threaded rod (114) is located at the output end of the drive motor (115). The drive motor (115) is installed inside the housing (101) on the side adjacent to the guide block (113) by bolts.

5. A rapid plate washer for cell engineering according to claim 4, characterized in that: Inside the housing (101), a first suction pump (116) and a second suction pump (117) are respectively bolted to the side adjacent to the drive motor (115). The suction end of the first suction pump (116) is connected to the suction connector (118) through a pipe passing through the housing (101), and the pumping end of the first suction pump (116) is connected to the diverter plate (109) through a pipe passing through the expansion groove (107).

6. A rapid plate washer for cell engineering according to claim 5, characterized in that: The suction end of the second suction pump (117) is connected to the groove (102) through a pipe and forms a through connection. The pumping end of the second suction pump (117) is connected to the discharge connector (119) after passing through the box (101) through a pipe. The suction connector (118) and the discharge connector (119) are respectively fixedly installed on the outside side of the box (101).

7. A rapid plate washer for cell engineering according to claim 6, characterized in that: A switch (120) is installed through the box (101) on the side opposite to the suction connector (118) and the discharge connector (119). A power cord (121) is installed through the box (101) on the side adjacent to the switch (120). A cover (122) is installed on the top of the box (101) on the side adjacent to the groove (102) via a hinge.

8. A rapid plate washer for cell engineering according to claim 7, characterized in that: A control box (123) is fixedly installed on the top of the housing (101) and on the side adjacent to the extension groove. A touch screen (124) is fixedly installed on the top of the control box (123). A circuit board (125) is installed inside the control box (123) by bolts.

9. A rapid plate washer for cell engineering according to claim 8, characterized in that: The corresponding pins of the circuit board (125), touch screen (124), switch (120), power cord (121), drive motor (115), rotary motor (106), first suction pump (116) and second suction pump (117) are connected by flexible wires.

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