A kind of experimental animal detection laboratory enzyme labeled plate board strip vacuum drying storage box

By designing a vacuum drying storage box, and utilizing heating wires and desiccants, the problem of condensation caused by the unbalanced strips of the ELISA plate was solved, achieving rapid temperature balancing and stable storage of the ELISA plate, thus improving detection performance and lifespan.

CN224491937UActive Publication Date: 2026-07-14SUZHOU XISHAN BIOLOGICAL TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SUZHOU XISHAN BIOLOGICAL TECH
Filing Date
2025-06-27
Publication Date
2026-07-14

AI Technical Summary

Technical Problem

In laboratory animal testing, if the strips on the ELISA plate are not fully balanced, or if the temperature inside the wells is low after the packaging is opened prematurely, condensation may occur, affecting the detection performance and lifespan.

Method used

A vacuum drying and storage box for enzyme-labeled strips in an experimental animal testing laboratory was designed. It includes heating wires and heating plates, which can bring the enzyme-labeled strips to the same temperature as the outside environment within ten minutes. The vacuum drying and desiccant maintain a stable storage environment and prevent the formation of condensation.

Benefits of technology

To ensure the detection performance of ELISA plates, shorten waiting time, improve the convenience of experimental operation, and extend the service life of ELISA plates.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a kind of experimental animal detection laboratory enzyme mark plate strip vacuum drying storage box, including box and the box cover of installation in box upper side, the inside of the box is provided with internal frame, the left and right two ends outer wall of the internal frame and respectively close to left and right sides are uniformly connected with multiple supporting plates, the upper side of multiple supporting plate is provided with drawer, to provide the storage space of enzyme mark plate strip, the upper side of the box cover is provided with wet thermometer, to detect the temperature and humidity change in the inside of box, the upper side of the box cover is provided with inlet valve, to guide outside air to enter the inside of box, the right side of the inlet valve is provided with suction hole, to connect external vacuum pump, by installing heating wire and heating plate layer, it can be thirty to thirty-five degrees gentle heating, so that enzyme mark plate strip in the inside of drawer reaches and outside temperature consistent within ten minutes, to ensure enzyme mark plate detection performance.
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Description

Technical Field

[0001] This utility model belongs to the technical field of experimental equipment, specifically relating to a vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) plates in an experimental animal testing laboratory. Background Technology

[0002] The vacuum drying and storage box for ELISA strips in laboratory animal testing is a device specifically designed for storing ELISA strips in the field of laboratory animal testing. It aims to provide an ideal storage environment for the ELISA strips to ensure their quality and performance, and to ensure the accuracy and reliability of experimental results.

[0003] However, when performing enzyme-linked immunosorbent assays (ELISA) to detect pathogen antigens or antibodies in laboratory animals, failure to fully equilibrate the ELISA plate before use, premature opening of the packaging, and low temperatures inside the wells may cause condensation, affecting the detection performance and lifespan of the ELISA plate. Utility Model Content

[0004] The purpose of this invention is to provide a vacuum drying and storage box for enzyme-labeled plates in laboratory animal testing, in order to solve the problems mentioned in the background art, such as insufficient equilibration before use, premature unpacking, low temperature inside the wells, which may cause condensation in the wells, affecting the detection performance and service life of the enzyme-labeled plates.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) plates in an experimental animal testing laboratory, comprising a box body and a box cover installed on the upper side of the box body;

[0006] The box is equipped with an internal frame.

[0007] Multiple support plates are fixedly connected to the outer walls of the left and right ends of the internal frame, respectively, close to the left and right sides.

[0008] Each of the trays has a drawer on its upper side to provide storage space for the ELISA strips. A humidity thermometer is installed on the upper side of the lid to detect changes in temperature and humidity inside the box. An air inlet valve is installed on the upper side of the lid to guide outside air into the box. An air extraction port is installed on the right side of the air inlet valve to connect to an external vacuum pump.

[0009] Each of the drawers has a heating plate layer on its lower inner wall, and each of the heating plate layers has a heating wire inside to diffuse heat outward after power is applied.

[0010] Preferably, the housing is equipped with a control power supply to provide power, and the internal frame is equipped with power lines to guide and distribute the power from the control power supply.

[0011] Preferably, multiple power supply heads are equidistantly arranged at both ends of the power cord from bottom to top to distribute the power. Each of the multiple heating plate layers has a power-conducting terminal on one side of its opposite side for connection with the power supply heads and to deliver power to the heating wire.

[0012] Preferably, the outer wall of the left end of the enclosure has a wiring through hole for connection with external power supply and control power supply.

[0013] Preferably, a storage box is fixedly connected to the lower inner wall of the box, and a desiccant is provided inside the storage box.

[0014] Preferably, a mesh is provided on the upper side of the storage box, and a front cover is provided on the front outer wall of the box near the lower side to cover and seal the storage box.

[0015] Preferably, each of the drawers has a second handle inside one end to move the drawer laterally under external force. Each of the second handles has a note clip on its upper side to hold a note with specific information about the corresponding enzyme-linked immunosorbent assay (ELISA) strip, such as the test item, batch number, and expiration date. Each of the drawers has a limiting frame inside to restrict the placement and spacing of the ELISA strips.

[0016] Preferably, the lower outer wall of the box cover has downward-opening grooves at the four corners, and the upper outer wall of the box body has sealing strips that are fixedly connected to the four corners and inserted into the grooves.

[0017] Preferably, the lid is provided with a first handle at each of the four ends (front, back, left, and right), and the box body is fixedly connected to a fastener at each of the four ends (front, back, left, and right). Each of the first handles has a buckle at one end to engage with the fastener and restrict the position of the lid.

[0018] Compared with the prior art, this utility model provides a vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in laboratory animal testing, which has the following beneficial effects:

[0019] By installing heating wires and heating plates, the heating wires can provide gentle heating at 30 to 35 degrees Celsius after being powered on. This allows the ELISA strips inside the drawer to reach the same temperature as the outside environment within ten minutes. This rapid temperature equilibration prevents condensation from forming in the wells due to sudden temperature changes, thus ensuring the performance of the ELISA plate and creating a stable starting environment for detection. Because the waiting time is shortened, researchers no longer need to take out the ELISA plate long in advance to allow it to equilibrate, improving the convenience of experimental operations. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of a vacuum drying and storage box for enzyme-labeled plates in an experimental animal testing laboratory according to the present invention.

[0021] Figure 2 This is a partial structural schematic diagram of the front cross-section of the box area of ​​this utility model.

[0022] Figure 3 This is a partial structural schematic diagram of the first handle area side view of this utility model.

[0023] Figure 4 This is a partial structural schematic diagram of the frontal cross-section of the internal frame area of ​​this utility model.

[0024] In the diagram: 1. Box body; 2. First handle; 3. Box lid; 4. Wet thermometer; 5. Air inlet valve; 6. Air extraction port; 7. Note clip; 8. Second handle; 9. Drawer; 10. Wiring through hole; 11. Control power supply; 12. Storage box; 13. Desiccant; 14. Partition mesh; 15. Fastener; 16. Buckle; 17. Groove; 18. Sealing strip; 19. Internal frame; 20. Power terminal; 21. Power supply head; 22. Power cord; 23. Heating wire; 24. Heating plate layer; 25. Support plate; 26. Front cover; 27. Limiting frame. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] This utility model provides, for example Figures 1-4 The experimental animal testing laboratory enzyme-labeled plate strip vacuum drying and storage box shown includes a box body 1 and a box cover 3 installed on the upper side of the box body 1;

[0027] The interior of the housing 1 is equipped with an internal frame 19;

[0028] Multiple support plates 25 are fixedly connected to the outer walls of the left and right ends of the internal frame 19, respectively, close to the left and right sides.

[0029] Each tray 25 has a drawer 9 on its upper side to provide storage space for ELISA strips. A humidity thermometer 4 is located on the upper side of the lid 3 to monitor temperature and humidity changes inside the chamber 1. An air inlet valve 5 is located on the upper side of the lid 3 to allow outside air into the chamber 1. An exhaust port 6 is located to the right of the air inlet valve 5 to connect to an external vacuum pump. Place the ELISA strips into their corresponding drawers 9, close the drawers 9, and store different types of ELISA strips in the sixteen drawers 9 according to their classification. Close the lid 3 and place the chamber inside. The lid 3 is securely fixed to the box body 1. Connect the vacuum pump to the air extraction port 6, close the air inlet valve 5, start the vacuum pump to evacuate the box body 1, observe the humidity thermometer 4, and ensure that the humidity inside the box is within the range of 10% to 15%. Then, place the vacuum-evacuated and well-sealed storage box into a refrigerator at 2 to 8 degrees Celsius for storage. When it is needed, take the storage box out of the refrigerator, open the air inlet valve 5, and let the outside air slowly enter the box body 1 to balance the air pressure inside and outside the box. After the air pressure is balanced, open the lid 3 and take out the enzyme labeling strips from the corresponding drawer 9 as needed.

[0030] Each of the drawers 9 has a heating plate layer 24 on its lower inner wall. Each of the heating plate layers 24 has a heating wire 23 inside to diffuse heat outward after power is applied. When the storage box is taken out of the refrigerator, the power is turned on and the heating wire 23 is activated to heat the enzyme-labeled strips in the drawer 9. The temperature displayed on the wet thermometer 4 is observed. When the temperature reaches the ambient temperature, the heating is stopped and the power is cut off.

[0031] like Figure 2 and Figure 4 As shown, the housing 1 is equipped with a control power supply 11 to provide power. The internal frame 19 is equipped with a power cord 22 to guide the power of the control power supply 11 to be distributed. Multiple power supply heads 21 are arranged at equal intervals from bottom to top on both ends of the power cord 22 to distribute the power. Each of the multiple heating plate layers 24 has a power terminal 20 on one side of its opposite side to be connected to the power supply head 21 and to supply power to the heating wire 23.

[0032] The power supply 11 outputs power, which is transmitted to each power supply head 21 through the power cord 22. The power supply head 21 then transmits the power to the connected power terminal 20, and finally to the heating wire 23. After the heating wire 23 is powered on, it starts to heat up and gently heats the enzyme-labeled strips in the drawer 9 to 30 to 35 degrees Celsius, so that the enzyme-labeled strips reach the same temperature as the outside temperature within 10 minutes.

[0033] like Figure 2 As shown, a wiring through hole 10 is provided inside the outer wall of the left end of the housing 1 to connect with the external power supply and the control power supply 11.

[0034] The through-hole 10 is a plug structure, and an external power source is inserted into the through-hole 10 to power the control power source 11.

[0035] like Figure 2 As shown, a storage box 12 is fixedly connected to the lower inner wall of the box 1. A desiccant 13 is placed inside the storage box 12. A mesh 14 is placed on the upper side of the storage box 12. A front cover 26 is placed on the front outer wall of the box 1 near the lower side to cover and seal the storage box 12.

[0036] When the humid air inside the chamber comes into contact with the desiccant 13, the moisture molecules are adsorbed into the pores of the desiccant 13, thereby reducing the humidity of the air inside the chamber and creating a dry storage environment for the ELISA strips. The mesh 14 plays a key role in isolation, allowing air to circulate freely and enabling the humid air inside the chamber to fully contact the desiccant 13, ensuring that the desiccant effectively absorbs moisture. When it is necessary to replace the desiccant 13, the front cover 26 can be removed, and the desiccant 13 can be taken out from the storage box 12 for replacement. After replacement, the front cover 26 is closed again.

[0037] like Figure 1 As shown, each of the multiple drawers 9 has a second handle 8 inside one end, which can drive the drawer 9 to move laterally under the action of external force. Each of the multiple second handles 8 has a note clip 7 on the upper side, which can hold the specific information note of the corresponding enzyme label strip, such as the test item, batch, expiration date, etc. Each of the multiple drawers 9 has a limiting frame 27 inside, which can limit the placement position and spacing of the enzyme label strip.

[0038] When the operator applies external force to pull the second handle 8, the drawer 9 will move laterally on the tray 25. The operator can record in detail the relevant information of the ELISA strips placed in the drawer 9 on a sticky note, such as the type, batch, expiration date, and applicable experimental type of the ELISA strips, and put the sticky note into the sticky note clip 7 for quick reference. The limiting frame 27, through its specific shape and size design, can limit the placement and spacing of the ELISA strips in the drawer 9, preventing the ELISA strips from shaking or colliding during the movement of the drawer 9, and avoiding damage to the ELISA strips due to mutual friction or impact.

[0039] like Figure 1 and Figure 3 As shown, the lower outer wall of the lid 3 has downward-opening grooves 17 at the four corners, and the upper outer wall of the body 1 has sealing strips 18 that are inserted into the grooves 17 at the four corners. The lid 3 has first handles 2 at the front, back, left and right ends, and the body 1 has fasteners 15 at the front, back, left and right ends. Each of the first handles 2 has a buckle 16 at one end to fasten with the fasteners 15 and restrict the position of the lid 3.

[0040] Lower the lid 3, aligning it with the body 1, so that the sealing strip 18 is accurately inserted into the groove 17. Ensure that the sealing strip 18 is in full contact with the groove 17 and forms a seal. Then, operate the first handle 2 at each of the four ends of the lid 3 in sequence to engage the buckles 16 with the corresponding fasteners 15 on the body 1. When it is necessary to remove the lid 3, open the buckles 16 on the first handle 2 at each of the four ends of the lid 3 in sequence to separate it from the fasteners 15.

[0041] The implementation principle of this embodiment is as follows: Place the ELISA strips into the corresponding drawers 9, close the drawers 9, and store the different types of ELISA strips in the sixteen drawers 9 according to the classification principle. Cover the box with the lid 3 and fix the lid 3 tightly to the box body 1. Connect the vacuum pump to the air extraction port 6, close the air inlet valve 5, start the vacuum pump to evacuate the box body 1, and observe the humidity thermometer 4 to ensure that the humidity inside the box is within the range of 10% to 15%. Then, place the vacuum-evacuated and well-sealed storage box into a refrigerator at 2 to 8 degrees Celsius for storage. When it is needed, take the storage box out of the refrigerator, open the air inlet valve 5 to allow outside air to slowly enter the box body 1 to balance the air pressure inside and outside the box. After the air pressure is balanced, open the lid 3 and take out the ELISA strips from the corresponding drawers 9 as needed. When taking the storage box out of the refrigerator, connect it to the power supply and start the heating wire 23 to heat the ELISA strips in the drawers 9. Observe the temperature displayed on the humidity thermometer 4. When the temperature reaches the ambient temperature, stop heating and disconnect the power supply.

[0042] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) plates in an experimental animal testing laboratory, comprising a box body (1) and a box cover (3) installed on the upper side of the box body (1); The box (1) is provided with an internal frame (19); Multiple trays (25) are fixedly connected to the outer walls of the left and right ends of the internal frame (19) and close to the left and right sides respectively. Each of the trays (25) is provided with a drawer (9) on its upper side to provide storage space for the enzyme labeling strips. A humidity thermometer (4) is provided on the upper side of the lid (3) to detect changes in temperature and humidity inside the box (1). An air inlet valve (5) is provided on the upper side of the lid (3) to guide outside air into the box (1). An air extraction hole (6) is provided on the right side of the air inlet valve (5) to connect to an external vacuum pump. Its features are: The lower inner walls of the multiple drawers (9) are provided with heating plates (24), and heating wires (23) are provided inside the multiple heating plates (24) to diffuse heat outward after being powered on.

2. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: The housing (1) is equipped with a control power supply (11) to provide power, and the internal frame (19) is equipped with a power line (22) to guide the power of the control power supply (11) to be distributed.

3. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 2, characterized in that: Multiple power supply heads (21) are equidistantly arranged from bottom to top on both ends of the power cord (22) to distribute the power. Each of the multiple heating plate layers (24) has a power terminal (20) on one side of its opposite side to be connected to the power supply head (21) and to transmit power to the heating wire (23).

4. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: The outer wall of the left end of the enclosure (1) is provided with a wiring through hole (10) for connection with the external power supply and the control power supply (11).

5. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: A storage box (12) is fixedly connected to the lower inner wall of the box (1), and a desiccant (13) is provided inside the storage box (12).

6. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 5, characterized in that: The upper side of the storage box (12) is provided with a mesh (14), and the front outer wall of the box body (1) is provided with a front cover (26) near the lower side to cover and seal the storage box (12).

7. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: Each of the drawers (9) has a second handle (8) inside one end, which can drive the drawer (9) to move laterally under the action of external force. Each of the second handles (8) has a note clip (7) on the upper side, which can hold the specific information note of the corresponding enzyme label strip. Each of the drawers (9) has a limiting frame (27) inside, which can limit the placement position and spacing of the enzyme label strip.

8. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: The lower outer wall of the box cover (3) has four corners with downward-opening grooves (17), and the upper outer wall of the box body (1) has four corners with sealing strips (18) that are inserted into the grooves (17) upward.

9. The vacuum drying and storage box for enzyme-linked immunosorbent assay (ELISA) strips in an experimental animal testing laboratory according to claim 1, characterized in that: The lid (3) is provided with a first handle (2) at all four ends. The box body (1) is fixedly connected to a fastener (15) at all four ends. Each of the first handles (2) is provided with a buckle (16) at one end to fasten to the fastener (15) and restrict the position of the lid (3).