A burette for drug detection
By designing a combined structure of a cylindrical valve core and a connecting cylinder, the problem of dead corners in burette cleaning was solved, enabling convenient cleaning and efficient operation of burettes for drug testing, and ensuring the accuracy and reproducibility of test data.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JINAN TONGLU PHARM TECH & DEV CO LTD
- Filing Date
- 2025-08-12
- Publication Date
- 2026-07-14
AI Technical Summary
Existing burettes have cleaning blind spots in drug testing, leading to the risk of cross-contamination and affecting the accuracy of test data and the reproducibility of experimental results.
A burette for drug testing was designed, which adopts a combination structure of cylindrical valve core and connecting cylinder. The smooth discharge and shut-off of drug solution can be achieved through manual operation. Combined with the frosted surface material and threaded connection, it ensures that the cleaning tool can be cleaned without dead corners.
It enables convenient cleaning of burettes, avoids cross-contamination, ensures the accuracy of test data and the reproducibility of experimental results, and improves operational convenience and response efficiency.
Smart Images
Figure CN224500548U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of drug testing equipment technology, specifically a burette for drug testing. Background Technology
[0002] Burettes can accurately measure the volume of liquids, which is crucial for the quantitative analysis of drug components, the analysis of active ingredient content, and the detection of impurities. For example, they can determine the content of acidic or alkaline components in drugs, detect reducing substances or oxidizing impurities in drugs, analyze the content of metal ions, and ensure that drugs meet safety standards.
[0003] Based on differences in valve structure, burettes on the market can be mainly divided into the following three categories: glass piston burettes, rubber tubing burettes, and polytetrafluoroethylene (PTFE) stopcock burettes. Among them, glass piston burettes are suitable for acidic solution testing, while plastic valve core burettes are specifically used for alkaline media analysis. PTFE stopcock burettes, due to their excellent chemical inertness, are mostly used for the precision titration of highly corrosive reagents.
[0004] However, all three types of burettes mentioned above have common drawbacks in practical applications: after the solution is measured, residual liquid remains on the inner wall of the cylindrical cavity where the piston and the bottom of the tube are integrally formed, creating many cleaning dead zones and making cleaning difficult; especially at the connection between the cylindrical cavity and the tube body, solution easily remains, and cleaning tools cannot effectively reach in; when used in drug detection, this increases the risk of sample cross-contamination, directly affecting the accuracy of the detection data and the reproducibility of the experimental results, and in severe cases, it can lead to the invalidation of the entire batch of detection data; therefore, this application provides a burette for drug detection. Utility Model Content
[0005] To address the shortcomings of the existing technology, the present invention aims to provide a burette for drug testing. This product ensures sealed use and stable titration capability of the solution, while also being easy to clean. There are no dead corners in the tube, which can avoid cross-contamination when testing different drug solutions, thus ensuring the accuracy of the test data and the reproducibility of the experimental results.
[0006] The technical solution adopted by this utility model to solve its technical problem is as follows:
[0007] A burette for drug testing is provided, comprising a burette body, with an opening for filling solution and a titration orifice respectively provided at the upper and lower ends of the burette body, and a scale provided on the outer side of the burette body. A connecting cylinder is provided on the side of the burette body, and the connecting cylinder extends obliquely along the upper side of the burette body. A cylindrical valve core is slidably installed inside the connecting cylinder.
[0008] The cylindrical valve core is made of glass or polytetrafluoroethylene with a frosted surface on the outside.
[0009] Furthermore, a transfer control frame is slidably mounted on the outside of the burette body, and a T-shaped pin is provided at one end of the cylindrical valve core located on the outside of the burette body. The T-shaped pin is slidably connected to the sliding groove on the transfer control frame.
[0010] Furthermore, two T-shaped pins are provided, with the two T-shaped pins respectively located on both sides of the cylindrical valve core.
[0011] Furthermore, the T-pin has a threaded protrusion on the outer side of its end, and the cylindrical valve core has a threaded groove. The T-pin and the cylindrical valve core are connected by threaded engagement.
[0012] In this application, one optional technical solution for the use of the connecting cylinder and the cylindrical valve core is as follows: one connecting cylinder is provided, and one end of the cylindrical valve core inserted into the inner side of the burette body can abut against the inner wall of the burette body.
[0013] In this application, one optional technical solution for the use of the connecting cylinder and the cylindrical valve core is as follows: two connecting cylinders are provided, and the two connecting cylinders are symmetrically arranged on both sides of the burette body, and the two cylindrical valve cores are inserted into the inner side of the burette body so that they can abut and fit together.
[0014] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0015] 1. The burette for drug detection in this utility model allows for manual removal of the cylindrical valve core or reinsertion into the connecting tube, enabling the smooth discharge or shut-off of the drug solution within the burette body, and allowing the discharge of a specified amount of drug solution as needed. Since the diameter of the connecting channel between the cylindrical valve core and the burette body corresponds to the inner wall diameter of the burette body, cleaning tools can be smoothly inserted into the burette body to clean both the burette body and the inner wall of the connecting tube, eliminating cleaning dead zones and preventing cross-contamination when testing different drug solutions, thus ensuring the accuracy of the test data and the reproducibility of the experimental results.
[0016] 2. The burette for drug testing in this utility model example allows for manual holding of the transfer control frame, which slides vertically on the outside of the burette body, causing two cylindrical valve cores to be simultaneously pulled out or inserted from their respective connecting cylinders, increasing the ease of operation of the equipment. Compared to the solution using a single cylindrical valve core, the above operation can shorten the movement range of a single cylindrical valve core and achieve high response efficiency.
[0017] 3. In the burette for drug detection of this utility model, the T-pin and the cylindrical valve core are connected by threaded engagement; by rotating the T-pin, the T-pin can be removed from the cylindrical valve core so as to replace the cylindrical valve core with one of different materials to deal with drug solutions with different properties. Attached Figure Description
[0018] Other features, objects, and advantages of this application will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings:
[0019] Figure 1 This is a schematic diagram of the overall structure of the burette for drug testing provided by this utility model. Figure 1 ;
[0020] Figure 2 Cross-sectional view of the burette body provided by this utility model Figure 1 ;
[0021] Figure 3 Cross-sectional view of the burette body provided by this utility model Figure 2 ;
[0022] Figure 4 This is a schematic diagram of the structure of the burette for drug testing provided by this utility model. Figure 1 ;
[0023] Figure 5 This is a schematic diagram of the overall structure of the burette for drug testing provided by this utility model. Figure 2 ;
[0024] Figure 6 This is a schematic diagram of the structure of the burette for drug testing provided by this utility model. Figure 2 .
[0025] In the figure: 11, burette body; 111, scale; 12, burette orifice; 13, connecting tube; 14, annular part; 21, cylindrical valve core; 211, T-pin; 22, transfer control frame. Detailed Implementation
[0026] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of this utility model, but not all embodiments.
[0027] The components of the present invention embodiments described and shown in the accompanying drawings can typically be arranged and designed in a variety of different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention.
[0028] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.
[0029] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.
[0030] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0031] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. Furthermore, for ease of description, only the parts relevant to the utility model are shown in the accompanying drawings.
[0032] Example 1:
[0033] like Figure 1 As shown, this embodiment provides a burette for drug testing, including a burette body 11. The upper and lower ends of the burette body 11 are respectively provided with an opening for filling the solution and a titration orifice 12. An annular portion 14 is integrally formed on the top of the burette body 11 to prevent the top edge of the burette body 11 from being too sharp and cutting the operator. A scale 111 is provided on the outer side of the burette body 11. A connecting cylinder 13 is integrally formed on the side of the burette body 11. The connecting cylinder 13 extends obliquely along the upper side of the burette body 11 to prevent leakage of the drug solution at the connecting cylinder 13. A cylindrical valve core 21 is slidably installed inside the connecting cylinder 13. The connecting cylinder 13 is relatively long, which can maintain a seal at the contact point between the cylindrical valve core 21 and the connecting cylinder 13.
[0034] The cylindrical valve core 21 is made of glass or polytetrafluoroethylene with a frosted surface on the outside.
[0035] In this embodiment, one communicating tube 13 is provided, such as Figure 3 As shown, the end of the cylindrical valve core 21 inserted into the inner side of the burette body 11 can abut against the inner wall of the burette body 11.
[0036] When using the burette for drug testing as described in this application;
[0037] First, manually hold the upper end of the cylindrical valve core 21 and insert it into the communicating tube 13 to seal the bottom of the burette body 11. Then, pour the drug solution into the burette body 11 from the upper side until the specified scale 111 is reached. Under the action of the cylindrical valve core 21, the drug solution that has entered the burette body 11 cannot be discharged.
[0038] Afterward, let the burette body 11 stand for two to three minutes to allow the air bubbles in the drug solution inside the burette body 11 to be fully expelled;
[0039] Finally, manually pull out the cylindrical valve core 21 or reinsert the cylindrical valve core 21 into the connecting tube 13 to allow the drug solution in the burette body 11 to drain smoothly or stop draining, and drain the specified amount of drug solution as needed.
[0040] When using the above-mentioned scheme of this application, since the diameter of the communication channel between the cylindrical valve core 21 and the burette body 11 corresponds to the inner wall diameter of the burette body 11, the cleaning tool can be smoothly inserted into the burette body 11 to clean the inner wall of the burette body 11 and the connecting cylinder 13 without cleaning dead corners, avoiding cross-contamination when testing different drug solutions, and ensuring the accuracy of the test data and the reproducibility of the experimental results.
[0041] Example 2:
[0042] The features that are the same as those in Embodiment 1 will not be repeated here. The difference between this embodiment and Embodiment 1 is that: Figure 1 and Figure 2 , Figure 4 , Figure 5 and Figure 6 As shown, in this embodiment, there are two connecting cylinders 13, which are symmetrically arranged on both sides of the burette body 11. The two cylindrical valve cores 21 are inserted into the inner side of the burette body 11 and can abut against each other.
[0043] To facilitate synchronous control of the two cylindrical valve cores 21, such as Figure 1 , Figure 4 , Figure 5 and Figure 6As shown, a transfer control frame 22 is slidably installed on the outside of the burette body 11. A T-shaped pin 211 is provided at one end of the cylindrical valve core 21 located on the outside of the burette body 11. The T-shaped pin 211 is slidably connected to the sliding groove on the transfer control frame 22. There are two T-shaped pins 211, which are respectively located on both sides of the cylindrical valve core 21.
[0044] Manually holding the transfer control frame 22 allows it to slide vertically outside the burette body 11, causing the two cylindrical valve cores 21 to be simultaneously pulled out or inserted from their respective connecting cylinders 13, increasing the ease of operation of the equipment; the transfer control frame 22 is composed of, as shown in the figure Figure 4 The two assemblies shown are joined together by fasteners in opposite directions, making them easy to disassemble.
[0045] Compared to the solution using a single cylindrical valve core 21 in Embodiment 1, the solution described in this embodiment can shorten the movement range of a single cylindrical valve core 21 and achieve higher response efficiency.
[0046] Example 3:
[0047] The features that are the same as those in Embodiment 1 will not be repeated here. The difference between this embodiment and Embodiment 1 is that: Figure 4 and Figure 6 As shown, in this embodiment, the outer end of the T-pin 211 is provided with a threaded protrusion, and the cylindrical valve core 21 is provided with a threaded groove. The T-pin 211 and the cylindrical valve core 21 are connected by threaded engagement. By rotating the T-pin 211, the T-pin 211 can be removed from the cylindrical valve core 21 so that cylindrical valve cores of different materials can be used to deal with drug solutions with different properties.
[0048] The above description is merely a preferred embodiment of this application and an explanation of the technical principles employed. Those skilled in the art should understand that the scope of the utility model involved in this application is not limited to the technical solutions formed by specific combinations of the above-described technical features, but should also cover other technical solutions formed by arbitrary combinations of the above-described technical features or their equivalents without departing from the inventive concept. For example, technical solutions formed by substituting the above features with (but not limited to) technical features with similar functions disclosed in this application.
[0049] Apart from the technical features described in the specification, the other technical features are known to those skilled in the art. To highlight the innovative features of this utility model, the other technical features will not be described in detail here.
Claims
1. A burette for drug testing, comprising a burette body (11) with graduations (111) on its outer surface, and a burette orifice (12) at the bottom of the burette body (11), characterized in that, The burette body (11) has an integrally formed connecting tube (13) on its side. The connecting tube (13) extends obliquely along the upper side of the burette body (11), and a cylindrical valve core (21) is slidably installed inside the connecting tube (13).
2. The burette for drug detection according to claim 1, characterized in that, The connecting tube (13) is provided with one end of the cylindrical valve core (21) inserted into the inner side of the burette body (11) so that it can abut against the inner wall of the burette body (11).
3. The burette for drug detection according to claim 1, characterized in that, Two connecting cylinders (13) are provided, and the two connecting cylinders (13) are symmetrically arranged on both sides of the burette body (11). The two cylindrical valve cores (21) are inserted into the inner side of the burette body (11) and can abut against each other.
4. The burette for drug detection according to claim 2 or 3, characterized in that, A transfer control frame (22) is slidably installed on the outside of the burette body (11). A T-shaped pin (211) is provided at one end of the cylindrical valve core (21) located on the outside of the burette body (11). The T-shaped pin (211) is slidably connected to the slide groove on the transfer control frame (22).
5. The burette for drug detection according to claim 4, characterized in that, Two T-pins (211) are provided, and the two T-pins (211) are respectively provided on both sides of the column valve core (21).
6. The burette for drug detection according to claim 1, characterized in that, The cylindrical valve core (21) is made of glass with a frosted surface on the outside.
7. The burette for drug detection according to claim 1, characterized in that, The cylindrical valve core (21) is made of polytetrafluoroethylene.
8. The burette for drug detection according to claim 1, characterized in that, The top of the burette body (11) is integrally formed with an annular portion (14).
9. The burette for drug detection according to claim 5, characterized in that, The T-pin (211) has a threaded protrusion on the outer side of its end, and the cylindrical valve core (21) has a threaded groove. The T-pin (211) and the cylindrical valve core (21) are connected by threaded engagement.