一种便于拆装的组合式制备色谱柱

Abstract

本实用新型涉及色谱柱技术领域，具体为一种便于拆装的组合式制备色谱柱，包括固定架、挡板、出液管、进液管、填料盒和限位组件，固定架一端连接挡板，挡板上连接出液管，固定架另一端连接进液管，固定架上连接多个填料盒，多个填料盒沿固定架轴线前后平行设置，限位组件连接在固定架上，进液管与限位组件连接，限位组件包括压板、支撑块、调节旋钮、螺纹杆和移动套。本实用新型中，将多个平行分布呈柱状的填料盒安装在固定架上，限位组件中的压板能够沿固定架中轴线方向移动，通过螺纹杆和移动套之间的配合推动压板沿固定架中轴线方向移动调节其与与挡板之间的间距变化，进而使其适应不同尺寸和不同数量的填料盒。

Claims

1. A modular preparative chromatography column that is easy to disassemble, characterized in that, include A fixed frame (1) is connected to a baffle (2) at one end, and a liquid outlet pipe (3) is connected to the baffle (2). A liquid inlet pipe (4) is connected to the other end of the fixed frame (1). Multiple packing boxes (5) are connected to the fixed frame (1). The multiple packing boxes (5) are arranged in parallel front and back along the axis of the fixed frame (1). The limiting component is connected to the fixed frame (1), and the liquid inlet pipe (4) is connected to the limiting component. The limiting component includes a pressure plate (6), a support block (7), an adjustment knob (8), a threaded rod (9), and a movable sleeve (10). The support block (7) is detachably connected to the fixed frame (1). The two ends of the support block (7) are respectively provided with an adjustment knob (8) and a pressure plate (6). The pressure plate (6) is connected to the movable sleeve (10). The pressure plate (6) has a through hole, which is connected to the liquid inlet pipe (4). The adjustment knob (8) is connected to a threaded rod (9) that is threadedly connected to the movable sleeve (10). When the limiting component is in use, the adjustment knob (8) rotates, which drives the threaded rod (9) to rotate, which drives the moving sleeve (10) to move along the axis of the fixed frame (1). The distance between the pressure plate (6) and the baffle (2) is reduced, which applies an axial clamping force to the packing box (5).

2. The combined preparative chromatography column according to claim 1, characterized in that The limit component also includes Guide sleeves (11) are distributed in multiples, and the guide sleeves (11) are connected to the receiving grooves opened on the support block (7); The number of guide rods (12) corresponds to the number of guide sleeves (11). The guide rods (12) are connected to the pressure plate (6) and are slidably connected to the guide sleeves (11).

3. The combined preparative chromatography column according to claim 1, wherein, The fixing frame (1) consists of multiple limiting rings (13) and connecting rods (14). The limiting rings (13) are arranged parallel to the central axis of the stuffing box (5), and the multiple connecting rods (14) are distributed in a circle with the central axis of the stuffing box (5) as the center. The connecting rods (14) are connected to the limiting rings (13).

4. The combined preparative chromatography column according to claim 1, wherein, The two ends of the packing box (5) are respectively connected to a fixed filter screen (15) and a movable filter screen (16). The fixed filter screen (15) is fixedly connected to the bottom of the packing box (5), and the movable filter screen (16) is detachably connected to the packing.

5. The modular preparative chromatography column of claim 4, wherein, The movable filter screen (16) consists of a mounting frame (17) and a mesh plate (18). The mesh plate (18) is connected to the annular mounting frame (17). The mounting frame (17) has multiple protrusions (19). The filler box (5) has L-shaped limiting grooves (20) with a number corresponding to the number of protrusions (19).

6. The modular preparative chromatography column of claim 1, wherein, The packing material is a silica gel-based chromatographic packing material or a gel packing material.

7. The modular preparative chromatography column of claim 1, wherein, Each of the adjacent stuffing boxes (5) is connected to a sealing ring (21).

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