一种医药合成实验用无水无氧装置
By designing an insulating plug and an electric push rod assembly on the glove box, non-destructive glove replacement is achieved, solving the problems of cumbersome and costly glove replacement in existing technologies and ensuring the efficient conduct of anhydrous and oxygen-free experiments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- NANJING KANGLIRUI BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-05-12
- Publication Date
- 2026-07-17
AI Technical Summary
Existing glove boxes require the vacuum chamber to be emptied of its negative pressure when changing gloves, which is cumbersome and costly, making it difficult to achieve an efficient anhydrous and oxygen-free experimental environment.
An anhydrous and oxygen-free device for pharmaceutical synthesis experiments was designed. It employs an isolation plug and an electric push rod assembly. The electric push rod pushes the isolation plug to separate the inside of the glove box from the outside, enabling non-destructive glove replacement. An airbag and drive gear system ensures airtightness.
This eliminates the need to evacuate the vacuum during glove changing, simplifying operations, reducing daily operating costs, and ensuring the glove box remains airtight and in a water- and oxygen-free environment.
Smart Images
Figure CN224509765U_ABST
Abstract
Claims
1. An anhydrous and oxygen-free apparatus for pharmaceutical synthesis experiments, comprising a glove box (10) and two glove connection ports disposed on the glove box (10), characterized in that: Each of the glove connection ports is equipped with an air hood (20). The air hood (20) has a side seat block (201) and an installation plug block (202) respectively on both sides inside. An expansion groove (204) communicating with the inside of the air hood (20) is provided between the side seat block (201) and the installation plug block (202). An isolation plug block (30) is slidably provided inside the expansion groove (204). The lower end of the isolation block (30) is provided with a drive assembly for controlling the lifting and lowering of the isolation block (30). The isolation block (30) is provided with a receiving cavity (301). The receiving cavity (301) is provided with an air collecting groove (302) and a slidingly mounted moving plate (303). A squeezing piston (304) slides inside the air collecting groove (302). An air bag (305) is installed on the side of the moving plate (303) away from the squeezing piston (304). The air bag (305) and the inside of the air collecting groove (302) are connected by an air pipe that passes through the moving plate (303).
2. The apparatus according to claim 1, wherein: The side seat block (201) is provided with a vent (203) that communicates with the inside of the glove box (10). A glove is installed on the mounting block (202), and the vent (203) is penetrated by the glove and extends into the inside of the glove box (10).
3. The apparatus as claimed in claim 1, wherein the apparatus is used for the synthesis of pharmaceuticals in an anhydrous and oxygen-free environment. One end of the air vent (20) is set as an opening, and the mounting plug (202) is located at the opening of the air vent (20). The mounting plug (202) is fixed by bolts, and several sealing rings are provided on the side wall in contact with the air vent (20).
4. The anhydrous and anaerobic apparatus for pharmaceutical synthesis experiment according to claim 1, characterized in that: The drive assembly is configured as two sets of electric push rods (205), with the two ends of the electric push rods (205) connected to the isolation block (30) and the bottom wall of the expansion groove (204), respectively.
5. The apparatus as claimed in claim 2, wherein: The airbags (305) are connected end to end and form a rectangle. After the isolation plug (30) is pushed up by the drive assembly, the vent (203) is located inside the rectangular airbags (305).
6. The anhydrous and anaerobic apparatus for pharmaceutical synthesis experiment according to claim 1, characterized in that: The cavity (301) is equipped with a drive gear (306) that rotates in the center. The drive gear (306) is connected to a screw (307) on its shaft. The other end of the screw (307) is threaded to a sleeve (308). The other end of the sleeve (308) is mounted on a movable plate (303).
7. The apparatus as claimed in claim 6, wherein: A rack (309) connected to the inner wall of the receiving cavity (301) is provided directly above the isolation plug (30). The rack (309) extends into the receiving cavity (301) and is connected to the extrusion piston (304). The rack (309) meshes with the drive gear (306).