一种测湿预警装载片及其组成的自补水基因测序装置
By designing a self-humidifying early warning loading box, the system utilizes humidity sensors and electronic control components to monitor and replenish humidity in real time, solving the humidity control problem of Oxford nanopore gene sequencing chips and improving detection quality and chip lifespan.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- HEILONGJIANG PROVINCIAL CENT FOR DISEASE CONTROL & PREVENTION (HEILONGJIANG PUBLIC HEALTH MONITORING & TESTING CENT)
- Filing Date
- 2025-08-20
- Publication Date
- 2026-07-17
AI Technical Summary
The Oxford nanopore gene sequencing chip, due to the lack of humidity monitoring and control measures during use, failed to detect humidity in a timely manner and maintain it within the predetermined range, thus affecting the test results.
A self-humidifying early warning loading box is designed, including a humidity monitoring and early warning loading plate and a self-hydrating gene sequencing device. Through an electronic control component consisting of a humidity sensor, a controller, and a battery, the humidity is monitored and replenished in real time to ensure that the gene sequencing chip is kept within a suitable humidity range during the detection process.
This technology enables real-time humidity monitoring and timely water replenishment of the gene sequencing chip during the detection process, ensuring the stability of the detection environment and the quality of detection, and extending the effective performance of the chip.
Smart Images
Figure CN224513502U_ABST
Abstract
Claims
1. A moisture warning loading sheet, characterized by: The utility model relates to a kind of gene sequencing chip storage box, including sheet shell (1), infiltrated connecting plate (2), communicating pipe (3) and electric control assembly, the sheet shell (1) is horizontally arranged, sheet shell (1) is rectangular flat box body, electric control assembly is arranged in sheet shell (1), the communicating pipe (3) is vertically worn in sheet shell (1), infiltrated connecting plate (2) is arranged above sheet shell (1), annular groove (4) is processed on the top surface of infiltrated connecting plate (2), first annular magnetic sheet (5) is arranged in annular groove (4), the groove bottom of annular groove (4) is processed with the first through hole (6) matched with communicating pipe (3), infiltrated connecting plate (2) is sleeved on communicating pipe (3) by first through hole (6), the bottom surface of infiltrated connecting plate (2) and sheet shell (1) form the clamping gap of adaptive gene sequencing chip (10) between.
2. The moisture warning loading sheet of claim 1, wherein: The electric control assembly includes a humidity sensor (8-1), a controller (8-2), and a battery (8-3). The humidity sensor (8-1), the controller (8-2), and the battery (8-3) are all arranged in the inner cavity of the rectangular box body. An installation hole (11) is processed on the bottom surface of the sheet shell (1) to communicate with the inner cavity. The probe end of the humidity sensor (8-1) is arranged in the installation hole (11). The humidity sensor (8-1) is connected to the battery (8-3) through the controller (8-2).
3. The moisture warning loading sheet of claim 1, wherein: The first annular magnetic sheet (5) includes a horizontal annular sheet (5-1) and a vertical annular sheet (5-2). The horizontal annular sheet (5-1) and the vertical annular sheet (5-2) are coaxially arranged. The horizontal annular sheet (5-1) is arranged on the groove bottom of the annular groove (4) along the radial direction of the annular groove (4). The vertical annular sheet (5-2) is vertically arranged on the groove side wall of the annular groove (4) along the circumferential direction of the annular groove (4).
4. The moisture warning loading sheet of claim 1, wherein: A sealing rubber sleeve (7) is coaxially arranged in the annular groove (4). The sealing rubber sleeve (7) is a conical sleeve, which is sleeved on the upper end of the communicating pipe (3).
5. A self-supplying water-based gene sequencing device, comprising a humidity warning loading sheet according to claim 1, 2, 3 or 4. The utility model relates to a kind of gene sequencing chip storage box, including measuring wet prewarning loading piece (21), lower box body (22), upper box body (23), water supply bag (24), upper communicating piece (25) and gene sequencing chip (10), lower box body (22) and upper box body (23) are sequentially arranged from bottom to top, the top of lower box body (22) is processed with first placement groove along its length direction, the bottom of upper box body (23) is processed with second placement groove along its length direction, lower box body (22) and upper box body (23) are detachably connected, when lower box body (22) and upper box body (23) are connected, placement cavity is formed between first placement groove and second placement groove, gene sequencing chip (10) is arranged in placement cavity, water supply bag (24) is arranged on upper box body (23), upper communicating piece (25) is worn in upper box body (23); The moisture measuring and early warning loading sheet (21) comprises a sheet-shaped shell (1), a soaking connecting disc (2), a communicating pipe (3) and an electric control assembly, the sheet-shaped shell (1) is horizontally arranged, the communicating pipe (3) is vertically arranged on the sheet-shaped shell (1), the soaking connecting disc (2) is arranged above the sheet-shaped shell (1), an annular groove (4) is formed on the top surface of the soaking connecting disc (2), a first annular magnetic sheet (5) is arranged in the annular groove (4), a first penetrating hole (6) matched with the communicating pipe (3) is formed on the bottom of the annular groove (4), the soaking connecting disc (2) is sleeved on the communicating pipe (3) through the first penetrating hole (6), and a clamping gap suitable for the gene sequencing chip (10) is formed between the bottom surface of the soaking connecting disc (2) and the sheet-shaped shell (1). The moisture measuring and early warning loading sheet (21) is arranged below the upper communicating piece (25), the sheet-shaped shell (1) is inserted at the sample inlet opening (10-1) of the gene sequencing chip (10), and the upper end of the communicating pipe (3) is communicated with the water supply bag (24) through the upper communicating piece (25).
6. The self-complementary water-based gene sequencing device of claim 5, wherein: The upper communicating piece (25) comprises a cylindrical plug, the lower end of the cylindrical plug is detachably connected with the top of the soaking connecting disc (2), a second penetrating hole (27) is formed on the cylindrical plug, the upper end of the second penetrating hole (27) is communicated with the water supply bag (24), the lower end of the second penetrating hole (27) is communicated with the upper end of the communicating pipe (3), and the lower end of the cylindrical plug is provided with a second annular magnetic sheet (26), when the lower end of the cylindrical plug is inserted into the soaking connecting disc (2), the first annular magnetic sheet (5) and the second annular magnetic sheet (26) are magnetically connected.