A test card for detecting the content of rhodioloside in traditional Chinese medicinal materials

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By setting a shielding structure on the test card to cover the drip hole and observation window when not in use, the problem of contamination of the test components by external factors is solved, ensuring the accuracy of the test results.

CN224518732UActive Publication Date: 2026-07-17HEBEI ELISHA BIOTECH CO LTD

Patent Information

Authority / Receiving Office: CN · China
Patent Type: Utility models(China)
Current Assignee / Owner: HEBEI ELISHA BIOTECH CO LTD
Filing Date: 2025-08-07
Publication Date: 2026-07-17

AI Technical Summary

Technical Problem

The drop position and observation position of existing test cards are easily affected by external factors, leading to contamination of the test components and affecting the test results.

Method used

A detection card was designed that uses side blocks, square shields, and circular shields to cover the drip hole and observation window when not in use, and slides a connecting plate to expose the detection position when in use, thus preventing external contamination.

Benefits of technology

It effectively prevents external factors from contaminating the internal components of the test card, ensuring the accuracy and reliability of the test results.

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Abstract

This utility model relates to the field of detection card technology and discloses a detection card for detecting the content of rhodioloside in traditional Chinese medicine, comprising a lower shell and an upper shell: the lower shell and the upper shell are attached to opposite sides, and a PVC sheet is disposed inside the lower shell; the upper surface of the upper shell is provided with a drip hole and an observation window, a side block is fixedly connected to the side of the upper shell, an L-shaped groove is formed inside the side block, and a connecting long plate is slidably connected to both ends of the L-shaped groove; a circular shielding plate is attached to the upper surface of the drip hole, and a square shielding plate is attached to the upper surface of the observation window. This detection card for detecting the content of rhodioloside in traditional Chinese medicine can effectively shield the drip hole and the observation window, avoiding interference from external factors with the detection components inside the detection card, thus ensuring the subsequent detection results. At the same time, the sliding structure facilitates dripping and observation of the detection results without hindering the normal operation of the device.

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Description

Technical Field

[0001] This utility model relates to the field of detection card technology, specifically a detection card for detecting the content of rhodioloside in traditional Chinese medicine. Background Technology

[0002] Rhodioloside (scientific name 2-(4-hydroxyphenyl)ethyl-β-D-glucopyranoside) is the main bioactive component of Rhodiola rosea, a precious traditional Chinese medicine and Tibetan medicine. It has significant antioxidant, anti-fatigue, anti-radiation and human function-enhancing effects. Studies have shown that rhodioloside mainly achieves immune regulation by improving the antioxidant capacity of cells, scavenging reactive oxygen species, regulating the expression of inflammatory cytokines and inhibiting the synthesis of inflammatory mediators. Due to its significant effects in anti-aging and protecting the cardiovascular system, rhodioloside is widely used in pharmaceuticals, skin care products, health products and dietary supplements.

[0003] Current detection strips typically use colloidal gold-labeled antibodies and consist of a base plate, an NC membrane, a sample pad, a conjugate pad, absorbent paper, and a casing. The sample pad delivers the sample to other parts of the strip and serves as a pretreatment function. The conjugate pad contains the label, which affects label release and detection sensitivity. The NC membrane is the main driving force for the chromatographic reaction and is also the site of the immune response and signal detection. The absorbent pad is located at the end of the strip and helps maintain the flow rate of the liquid on the membrane, preventing sample backflow.

[0004] When existing test cards are in use, the dropper and observation positions are mostly exposed to the outside, making them susceptible to external factors that can contaminate the internal detection components and thus affect subsequent test results.

[0005] Therefore, it is necessary to propose a detection card for detecting the content of rhodioloside in Chinese medicinal materials. Utility Model Content

[0006] To address the shortcomings of existing technologies, this invention provides a detection card for detecting the content of rhodioloside in traditional Chinese medicine. This card has the advantage of being able to shield the droplet and observation positions when not in use, thus preventing contamination of the detection components by external factors and solving the problems mentioned in the background art.

[0007] This utility model provides the following technical solution: a test card for detecting the content of rhodioloside in traditional Chinese medicinal materials, comprising a lower shell and an upper shell.

[0008] The lower housing and the upper housing are fitted together on opposite sides. The interior of the lower housing is provided with a PVC sheet. Insert rods are fixedly connected to both sides of the interior of the lower housing. Hollow rods are fixedly connected to both sides of the interior of the upper housing. The lower end of the hollow rod is inserted into the outer surface of the insert rod.

[0009] The upper surface of the upper housing is provided with a drip hole and an observation window. A side block is fixedly connected to the side of the upper housing. An L-shaped groove is provided inside the side block. A connecting plate is slidably connected to both ends of the L-shaped groove. A circular baffle is attached to the upper surface of the drip hole. A square baffle is attached to the upper surface of the observation window. The other ends of the two sets of side blocks are fixedly connected to the sides of the circular baffle and the square baffle, respectively.

[0010] Preferably, a sample pad is provided on one side of the upper surface of the PVC sheet, and a gold label pad is attached to the other side of the sample pad. An absorbent pad is provided on the other side of the upper surface of the PVC sheet. An NC film is attached to the opposite sides of the absorbent pad and the gold label pad. A detection line T and a control line C are respectively provided on the NC film. The gold label pad is coated with colloidal gold particles adsorbed with anti-rhodioloside monoclonal antibodies or latex microspheres or fluorescent microspheres chemically bonded with anti-rhodioloside monoclonal antibodies.

[0011] Preferably, the lower surface of the square shield is provided with a placement groove, and the upper surface of the drip hole and the side block connected to the drip hole is movably connected to the interior of the placement groove.

[0012] Preferably, a drop hole is provided above the upper surface of the sample pad, an observation window is provided above the upper surface of the NC membrane, the detection line T is located on the side close to the gold label pad, and the quality control line C is located on the side close to the absorption pad.

[0013] Preferably, the detection line T is coated with rhodioloside antigen, and the control line C is coated with goat anti-mouse secondary antibody.

[0014] Preferably, the lower shell and the upper shell cooperate to form a hollow cuboid, and the lengths of the lower shell and the upper shell are the same.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] This test card for detecting rhodioloside content in traditional Chinese medicine utilizes a combination of side blocks, a square shield, a circular shield, and a connecting plate. When the card is not in use, the circular shield is positioned directly above the drip hole, and the square shield is positioned directly above the observation window, effectively shielding the drip hole and observation window to prevent external contaminants from entering the card. In use, the connecting plate, with its other end sliding within an L-shaped groove on the side block, allows the circular and square shields to slide towards the center. The circular shield moves into a placement groove beneath the square shield, fully exposing the drip hole and observation window for subsequent testing. This structure effectively shields the drip hole and observation window, preventing external interference with the internal testing components and ensuring optimal results. Furthermore, the sliding mechanism facilitates drip application and result observation without hindering normal operation of the device. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of the device of this utility model;

[0019] Figure 2 This is a schematic diagram of the separate lower and upper shell structures of this utility model;

[0020] Figure 3 This is a schematic diagram of the upper surface structure of the upper shell of this utility model.

[0021] The attached diagram lists the components represented by each number as follows:

[0022] 1. Lower housing; 110. PVC sheet; 120. Sample pad; 130. Gold label pad; 140. NC film; 150. Detection line T; 160. Quality control line C; 170. Absorbent pad; 180. Insert rod;

[0023] 2. Upper shell; 210. Hollow rod; 220. Drip hole; 230. Observation window;

[0024] 3. Side block; 310. Square baffle; 311. Placement slot; 320. Circular baffle; 330. Connecting long plate; 340. L-shaped slot. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figure 1 , Figure 2 and Figure 3 A test card for detecting the content of rhodioloside in traditional Chinese medicine includes a lower shell 1 and an upper shell 2.

[0027] The lower housing 1 and the upper housing 2 are attached to each other on opposite sides. The interior of the lower housing 1 is provided with a PVC sheet 110. Insert rods 180 are fixedly connected to the two corners inside the lower housing 1. Hollow rods 210 are fixedly connected to the two corners inside the upper housing 2. The lower end of the hollow rod 210 is inserted into the outer surface of the insert rod 180.

[0028] The upper surface of the upper housing 2 is provided with a drip hole 220 and an observation window 230. A side block 3 is fixedly connected to the side of the upper housing 2. An L-shaped groove 340 is provided inside the side block 3. Both ends of the L-shaped groove 340 are slidably connected to a connecting long plate 330. A circular baffle plate 320 is attached to the upper surface of the drip hole 220. A square baffle plate 310 is attached to the upper surface of the observation window 230. The other ends of the two sets of side blocks 3 are fixedly connected to the sides of the circular baffle plate 320 and the square baffle plate 310, respectively. A placement groove 311 is provided on the lower surface of the square baffle plate 310. The upper surface of the drip hole 220 and the side block 3 connected to the drip hole 220 is movably connected to the interior of the placement groove 311.

[0029] When not in use, the circular shield 320 is positioned directly above the drip hole 220, and the square shield 310 is positioned directly above the observation window 230. The circular shield 320 and the square shield 310 shield the drip hole 220 and the observation window 230, thereby preventing external contaminants from entering the interior of the test card. When in use, since the sides of the circular shield 320 and the square shield 310 are respectively connected to the connecting long plates 330, and the other end of the connecting long plates 330 slides inside the L-shaped groove 340 opened on the side block 3, by moving the circular shield 320 and the square shield 310 towards the center, the circular shield 320 moves into the placement groove 311 opened on the lower side of the square shield 310. At this time, the drip hole 220 and the observation window 230 are fully exposed, and subsequent testing can be performed.

[0030] As a preferred technical solution of this utility model, a sample pad 120 is provided on one side of the upper surface of the PVC sheet 110, and a gold label pad 130 is attached to the other side of the sample pad 120. An absorbent pad 170 is provided on the other side of the upper surface of the PVC sheet 110. An NC membrane 140 is attached to the opposite side of the absorbent pad 170 and the gold label pad 130. A detection line T150 and a control line C160 are respectively provided on the NC membrane 140. The detection line T150 is coated with rhodioloside antigen, and the control line C160 is coated with goat anti-mouse secondary antibody.

[0031] The sample is pretreated using sample pad 120. The gold label pad 130 is coated with colloidal gold particles adsorbed with anti-rhodioloside monoclonal antibodies, or latex microspheres or fluorescent microspheres chemically bonded with anti-rhodioloside monoclonal antibodies. The NC membrane 140 has a detection line T150 coated with rhodioloside antigen and a control line C160 coated with goat anti-mouse secondary antibody. The principle is that the rhodioloside in the sample solution competes with the rhodioloside antigen on the T line to bind to the gold label antibody. When the rhodioloside content in the sample solution is high, more gold-labeled antibodies bind, resulting in fewer gold-labeled antibodies binding to the T line, and a lighter T line color. Conversely, when the rhodioloside content in the sample solution is low, fewer gold-labeled antibodies bind, resulting in more gold-labeled antibodies binding to the T line, and a darker T line color. The goat anti-mouse antibody in the C line can bind to all gold-labeled antibodies. Thus, the T and C lines exhibit different colors depending on the amount of rhodioloside in the sample solution. Qualitative detection cards can determine the rhodioloside content level by directly comparing the colors of the T and C lines; a darker T line often indicates a lower concentration of the target analyte in the sample solution. Quantitative detection cards can read the numerical values of the T and C lines using a reader; different values represent different contents. The rhodioloside content information can be directly obtained using a standard curve.

[0032] As a preferred technical solution of this utility model, a drop hole 220 is provided above the upper surface of the sample pad 120, an observation window 230 is provided above the upper surface of the NC membrane 140, a detection line T150 is provided on the side near the gold label pad 130, and a quality control line C160 is provided on the side near the absorption pad 170.

[0033] As a preferred technical solution of this utility model, the lower shell 1 and the upper shell 2 cooperate to form a hollow cuboid, and the lengths of the lower shell 1 and the upper shell 2 are the same.

[0034] The specific operating procedure is as follows: Place the test card on the constant temperature incubator, use a pipette to draw 120 μL of the sample solution containing icariin and add it vertically into the drop hole 220 of the test card, cover the incubator, incubate for 10 minutes, take out the test card after incubation and immediately insert it into the liquid addition hole of the reader, click "Start Test" and read the result.

[0035] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0036] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A test card for detecting the content of rhodioloside in traditional Chinese medicinal materials, comprising a lower shell (1) and an upper shell (2), characterized in that: The lower housing (1) and the upper housing (2) are attached to each other on opposite sides. The interior of the lower housing (1) is provided with a PVC sheet (110). Insert rods (180) are fixedly connected to both sides of the interior of the lower housing (1). Hollow rods (210) are fixedly connected to both sides of the interior of the upper housing (2). The lower end of the hollow rod (210) is inserted into the outer surface of the insert rod (180). The upper surface of the upper housing (2) is provided with a drip hole (220) and an observation window (230). A side block (3) is fixedly connected to the side of the upper housing (2). An L-shaped groove (340) is provided inside the side block (3). A connecting long plate (330) is slidably connected to both ends of the L-shaped groove (340). A circular baffle plate (320) is attached to the upper surface of the drip hole (220). A square baffle plate (310) is attached to the upper surface of the observation window (230). The other ends of the two sets of side blocks (3) are fixedly connected to the sides of the circular baffle plate (320) and the square baffle plate (310) respectively.

2. The detection card for detecting the content of salidroside in traditional Chinese medicinal materials according to claim 1, characterized in that: A sample pad (120) is provided on one side of the upper surface of the PVC sheet (110), and a gold label pad (130) is attached to the other side of the sample pad (120). An absorbent pad (170) is provided on the other side of the upper surface of the PVC sheet (110). An NC membrane (140) is attached to the opposite sides of the absorbent pad (170) and the gold label pad (130). A detection line T (150) and a quality control line C (160) are respectively provided on the NC membrane (140). The gold label pad (130) is sprayed with colloidal gold particles adsorbed with anti-rhodioloside monoclonal antibodies or latex microspheres or fluorescent microspheres chemically bonded with anti-rhodioloside monoclonal antibodies.

3. The detection card for detecting the content of salidroside in traditional Chinese medicinal materials according to claim 1, characterized in that: The lower surface of the square baffle plate (310) is provided with a placement groove (311), and the upper surface of the drip hole (220) and the side block (3) connected to the drip hole (220) is movably connected to the interior of the placement groove (311).

4. The detection card for detecting the content of salidroside in traditional Chinese medicinal materials according to claim 2, characterized in that: A drop hole (220) is provided above the upper surface of the sample pad (120), an observation window (230) is provided above the upper surface of the NC membrane (140), the detection line T (150) is located on the side close to the gold label pad (130), and the quality control line C (160) is located on the side close to the absorption pad (170).

5. The detection card for detecting the content of salidroside in traditional Chinese medicinal materials according to claim 2, characterized in that: The detection line T(150) is coated with rhodioloside antigen, and the control line C(160) is coated with goat anti-mouse secondary antibody.

6. The detection card for detecting the content of salidroside in traditional Chinese medicinal materials according to claim 1, characterized in that: The lower shell (1) and the upper shell (2) cooperate to form a hollow cuboid, and the lengths of the lower shell (1) and the upper shell (2) are the same.