A headgear for inducing a guinea pig myopia model

Abstract

The utility model discloses a headgear of guinea pig myopia model is induced, belongs to myopia prevention and control research technical field, including headgear main part, the neck of headgear main part is provided with fixed clothes, the top of headgear main part is provided with first magic tape, the left and right sides of headgear main part are provided with two eye holes, the eye hole is inlayed with myopia induction film, be provided with two forelimb hole on the fixed clothes. The utility model discloses through magic tape fixed mode realizes quick wearing and adjustment, need not anesthetic operation, significantly reduces the experiment risk and improves the animal cooperation degree, the skin damage problem is effectively avoided in combination with the air hole, the mouth opening and the ear hole, the adjustable characteristics of magic tape ensure the adaptation different guinea pig, the eye hole can be embedded translucent balloon or lens flexibly, support a variety of myopia induction mode, the quick dismounting design of magic tape is convenient for the eye inspection, dosing etc. operation, improves experimental efficiency greatly, provides efficient reliable tool for myopia research.

Description

Technical Field

[0001] This utility model relates to the field of myopia prevention and control research technology, and in particular to a headgear for inducing myopia in guinea pigs. Background Technology

[0002] Establishing a myopia model is a crucial foundation for studying the mechanisms of myopia development and prevention methods. Common induction methods currently include eyelid suturing, mask techniques (such as the balloon method and skull fixation method), and defocus lens induction.

[0003] However, existing technologies have significant drawbacks: eyelid suturing requires anesthesia, which can easily lead to eyelid adhesions and corneal damage, increasing the risk of infection, and postoperative examination requires a second surgery; in the mask method, the balloon method has poor air permeability, which can easily cause skin ulceration, and the mask is prone to falling off; the skull fixation method requires invasive procedures, has high anesthesia risks, and has poor model stability; defocus lens induction requires suturing the base to the periocular tissue, and repeated adhesion can easily cause tissue damage. These methods generally suffer from problems such as complex operation, low animal tolerance, poor adaptability, and inconvenient observation or treatment, which limit the study of myopia mechanisms.

[0004] Based on this, a headgear for inducing myopia in guinea pigs is proposed, which requires no anesthesia or invasive procedures, has high animal cooperation, effectively avoids skin damage, and is easy to operate. Utility Model Content

[0005] The purpose of this invention is to provide a headgear for inducing myopia in guinea pigs, in order to solve the problems in the background art.

[0006] To achieve the above objectives, this utility model provides a headgear for inducing myopia in guinea pigs, comprising a headgear body with multiple ventilation holes, a fixing garment at the neck of the headgear body, a first Velcro fastener at the top of the headgear body, two eye openings on the left and right sides of the headgear body, a myopia-inducing membrane embedded in the eye openings, and two forelimb openings on the fixing garment.

[0007] Preferably, the headgear body has an opening at the front end and an ear hole at the rear top of the headgear body, with the rear end of the ear hole connected to the fixed garment.

[0008] Preferably, the back of the garment is secured by overlapping and adhesive with a second hook and loop fastener, the second hook and loop fastener comprising a second loop fastener and a second hook fastener, the second hook fastener being attached to the bottom of the second loop fastener, and the width of the second hook fastener being greater than the width of the second loop fastener.

[0009] Preferably, the first hook and loop fastener includes a first hook-and-loop fastener and a first loop fastener, with the first hook-and-loop fastener fixedly disposed on the top of the headgear body.

[0010] Preferably, one end of the first textured hook and loop fastener is attached to the first hook and loop fastener, and the other end of the first textured hook and loop fastener passes through the ear hole and is fixedly connected to the second textured hook and loop fastener.

[0011] Preferably, the myopia-inducing film is configured as a semi-transparent balloon or lens.

[0012] Therefore, the headgear of the guinea pig myopia-inducing model of this invention, which adopts the above-described structure, has the following beneficial effects: (1) The fastening and adjustment can be achieved by fastening with Velcro, without the need to anesthetize the guinea pigs, which significantly reduces the risk of anesthesia and improves the animal's cooperation. Compared with methods that require invasive procedures or anesthesia, such as eyelid suturing and skull fixation, the operation process is simplified, the experimental preparation time is reduced, and the negative impact of secondary surgery or repeated anesthesia on the animals is avoided.

[0013] (2) The head cover body with ventilation holes is adopted, combined with the mouth opening and ear hole design, to fully ensure the guinea pig's breathing and heat dissipation needs, effectively avoiding the skin ulceration problem caused by excessive sealing of traditional mask methods (such as balloon method); there are no rigid fixing devices at the contact parts of the head cover and the animal, reducing friction and pressure, and further reducing the risk of skin damage.

[0014] (3) Through the adjustable design of the first and second Velcro straps, the headgear can be adapted to guinea pigs of different sizes and growth stages, ensuring the stability and long-term adaptability of the model during the experiment.

[0015] (4) A semi-transparent balloon (for form deprivation) or a lens (for defocus induction) is embedded in the eyepiece to realize a variety of myopia induction methods and meet diverse experimental needs.

[0016] (5) The first and second Velcro structures support quick disassembly. Only a portion of the adhesive area needs to be separated to expose the eye, facilitating non-invasive examination, drug administration, or adjustment of the induction device, thus greatly improving experimental efficiency.

[0017] The technical solution of this utility model will be further described in detail below with reference to the accompanying drawings and embodiments. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the present utility model; Figure 2 This is a left view of the headgear body according to an embodiment of the present utility model; Figure 3 This is a right view of the headgear body according to an embodiment of the present utility model; Figure 4 This is a schematic diagram of the fixed garment structure according to an embodiment of the present utility model; Figure 5 This is a schematic diagram of the first Velcro structure according to an embodiment of the present utility model; Figure label: 1. Headgear body; 2. Fixing garment; 3. Eye opening; 4. Myopia induction membrane; 5. Forelimb opening; 6. Mouth opening; 7. Ear opening; 8. Second loop fastener; 9. Second hook fastener; 10. First hook fastener; 11. First loop fastener; 12. Ventilation hole. Detailed Implementation

[0019] The technical solution of this utility model will be further described below with reference to the accompanying drawings and embodiments.

[0020] Unless otherwise defined, the technical or scientific terms used in this utility model shall have the ordinary meaning understood by one of ordinary skill in the art to which this utility model pertains. The terms "first," "second," and similar terms used in this utility model do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0021] Example like Figures 1-5 As shown, the headgear of this utility model for inducing myopia in guinea pigs includes a headgear body 1 with a neck opening and multiple ventilation holes 12. A fixing garment 2 is glued or sewn to the neck of the headgear body 1. The fixing garment 2 has two forelimb openings 5. When conducting the myopia induction experiment, the guinea pig's forelimbs are inserted through the forelimb openings 5, and the head is inserted into the headgear body 1. The fixing garment 2 and the two forelimb openings 5 ​​thereon can achieve the initial positioning of the headgear body 1 on the guinea pig's head.

[0022] The top of the headgear body 1 is attached with a first Velcro fastener. The front end of the headgear body 1 has a mouth opening 6 (to expose the guinea pig's mouth and nose, ensuring breathing and eating functions). The rear side of the top of the headgear body 1 has an ear hole 7, and the rear end of the ear hole 7 is directly connected to the fixing garment 2. The left and right sides of the headgear body 1 have two eye holes 3 symmetrically opened. Myopia induction film 4 is embedded or attached to the eye holes 3. The myopia induction film 4 is specifically a semi-transparent balloon (to achieve form deprivation), a lens (to achieve lens induction), etc.

[0023] In this embodiment, the headgear body 1 is made of two pieces of malleable and breathable non-woven fabric spliced ​​together, which is lightweight and has good breathability. The headgear body 1 has openings corresponding to the eyes, mouth and nose, ears and neck of the guinea pig. Other positions such as the top of the head, forehead and lower jaw area are connected as a whole by the same material. The mouth opening 6 at the mouth and nose can also be used to further position the headgear body 1 in conjunction with the fixing garment 2 and the forelimb opening 5.

[0024] The back of the garment 2 is secured by overlapping second hook and loop fasteners to allow for tightness adjustment. The second hook and loop fasteners include a second loop fastener 8 and a second hook fastener 9 (with the hook facing upwards). In this embodiment, the garment 2 is made of fan-shaped non-woven fabric spliced ​​together. The two ends of the seam are respectively sewn with the second loop fastener 8 or the second hook fastener 9. The second hook fastener 9 is attached to the bottom of the second loop fastener 8. The width of the second hook fastener 9 is greater than the width of the second loop fastener 8. The difference in width between the second hook fastener 9 and the second loop fastener 8 allows for tightness adjustment, which can adapt to the growth needs of guinea pigs of different sizes.

[0025] The first hook and loop fastener includes a first hook-and-loop fastener 10 and a first loop fastener 11. The first hook-and-loop fastener 10 is glued or sewn to the top of the headgear body 1 (hook side facing upward). One end of the first loop fastener 11 is glued to the first hook-and-loop fastener 10, and the other end of the first loop fastener 11 passes through the ear hole 7 and is sewn to the second loop fastener 8.

[0026] After the basic position of the headgear body 1 on the guinea pig's head is determined, adjust the first loop fastener 11 to the adhesive position of the first hook fastener 10, and tighten the back of the headgear body 1 so that the headgear body 1 fits tightly against the guinea pig's face, or the eye hole 3 is precisely aligned with the eyes.

[0027] This embodiment, based on the headgear used in the aforementioned induced guinea pig myopia model, successfully established a guinea pig form deprivation myopia model by attaching a semi-transparent balloon inside the eye opening 3. Experimental data showed that low myopia (-4.26±0.10 D) appeared after 4 weeks of form deprivation, developed into high myopia (-7.49±1.26 D) after 8 weeks, and reached (-10.50±0.61 D) after 10 weeks, achieving significant application effects and promoting in-depth research on the mechanism of myopia.

[0028] The method for wearing the headgear in the above-mentioned guinea pig myopia-inducing model is as follows: Separate the second hook-and-loop fastener 8 and the second hook-and-loop fastener 9 from the back of the garment 2, and simultaneously separate the first hook-and-loop fastener 10 and the first hook-and-loop fastener 11. At this point, the back of the headgear is fully extended. The guinea pig's forelimbs need to be inserted through the forelimb opening 5, and the mouth opening 6 should be extended from the snout. After completion, attach the second hook-and-loop fastener 8 and the second hook-and-loop fastener 9 to the back of the garment 2, adjusting the tightness to a suitable state. Then, gently pull the back of the headgear body and attach the first hook-and-loop fastener 11 to the appropriate position of the first hook-and-loop fastener 10, ensuring that the position of the eye hole 3 corresponds to the guinea pig's eyes, and at the same time, make the headgear body fit the guinea pig's face more closely, completing the wearing process. As the guinea pig grows, the tightness of the first and second hook-and-loop fasteners can be adjusted at any time to achieve a suitable fit.

[0029] When it is necessary to observe the guinea pig's eyes or apply medication, simply peel the first loop fastener 11 off the first hook fastener 10 to expose the eyes through the ear hole 7. The operation is convenient. After the inspection or medication is completed, press the first loop fastener 11 back to the original adhesive point to restore the headgear body 1 to a fitted state. There is no need to put it back on.

[0030] Therefore, this invention provides a headgear for inducing myopia in guinea pigs using the aforementioned structure. The headgear, secured with Velcro, allows for quick donning and adjustment without anesthesia, significantly reducing experimental risks and improving animal cooperation. The combination of ventilation holes, mouth opening, and ear opening effectively prevents skin damage. The adjustable nature of the Velcro ensures compatibility with guinea pigs of different sizes and growth stages. A semi-transparent balloon or lens can be flexibly inserted into the eye opening, supporting various myopia induction methods. The quick-release design of the Velcro facilitates eye examinations, drug administration, and other operations, greatly improving experimental efficiency. It offers significant advantages in simplifying operations, enhancing model stability, and multifunctionality, providing an efficient and reliable tool for myopia research.

[0031] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and not to limit it. Although the utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the technical solution of this utility model, and these modifications or equivalent substitutions cannot cause the modified technical solution to deviate from the spirit and scope of the technical solution of this utility model.

Claims

1. A headgear for inducing myopia in guinea pigs, characterized in that: The device includes a headgear body with multiple ventilation holes, a fixing garment at the neck of the headgear body, a first Velcro fastener at the top of the headgear body, two eye holes on the left and right sides of the headgear body, a myopia induction membrane embedded in the eye holes, and two forelimb openings on the fixing garment.

2. The headgear for inducing myopia in guinea pigs according to claim 1, characterized in that: The headgear body has an opening at the front end and an ear hole at the rear top of the headgear body. The rear end of the ear hole is connected to the fixed garment.

3. The headgear for inducing myopia in guinea pigs according to claim 2, characterized in that: The back of the garment is secured by overlapping and adhesive with a second type of hook and loop fastener. The second type of hook and loop fastener includes a second loop fastener and a second hook fastener. The second hook fastener is attached to the bottom of the second loop fastener, and the width of the second hook fastener is greater than the width of the second loop fastener.

4. The headgear for inducing myopia in guinea pigs according to claim 3, characterized in that: The first hook and loop fastener includes a first hook-and-loop fastener and a first loop fastener. The first hook-and-loop fastener is fixedly disposed on the top of the headgear body. One end of the first loop fastener is attached to the first hook-and-loop fastener, and the other end of the first loop fastener passes through the ear hole and is fixedly connected to the second loop fastener.

5. The headgear for inducing myopia in guinea pigs according to claim 1, characterized in that: The myopia-inducing film is set as a semi-transparent balloon or lens.

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