An auxiliary push device for a solid phase extraction cartridge

Abstract

The utility model relates to solid phase extraction auxiliary equipment technical field, specifically disclose a kind of auxiliary push device of solid phase extraction column, the auxiliary push device includes the push rod with scale ruler, the bottom end of push rod is provided with silica gel piston head, the circumferential outer wall of silica gel piston head is provided with multiple seal rings along its axis direction;The auxiliary push device simple structure, convenient operation, low pollution risk, the sealing between silica gel piston head and column inner wall is strong, uniform, stable linear pressure is exerted to liquid in solid phase extraction column, drive plugging liquid or eluent through adsorbent layer, reduce the risk of poor sealing, leading to uneven pressure and impurity pollution;Meanwhile, scale mark is set on push rod, it is convenient for user to accurately control the depth of pressing according to scale ruler, solve the problem that existing pressurization technology is all poor in sealing, low in pressure control precision, complex in operation and high in pollution risk.

Description

Technical Field

[0001] This utility model relates to the field of solid phase extraction auxiliary equipment technology, and in particular to an auxiliary booster device for a solid phase extraction column. Background Technology

[0002] Solid phase extraction (SPE) is a sample pretreatment technique widely used in chemical analysis, environmental monitoring, and biomedicine. Its core principle is the selective adsorption and elution of target substances by an adsorbent packed within a solid phase extraction column, achieving sample separation, purification, and concentration. However, in practice, solid phase extraction columns often become clogged with impurities in the sample (such as particulate matter, colloids, or high-viscosity substances), leading to impaired or even complete stagnation of liquid flow, severely impacting extraction efficiency and result accuracy.

[0003] To address this issue, existing technologies primarily employ the following pressurization methods to drive liquid through a solid-phase extraction column: 1. Syringe injection method: This method involves directly connecting a medical syringe to the extraction column and manually pushing the piston to apply pressure. However, this method has significant drawbacks: poor sealing at the interface between the syringe piston and the column can easily lead to pressure leakage, resulting in uneven pressure distribution and even liquid splashing; furthermore, manual operation makes it difficult to achieve continuous and stable pressure control, affecting reproducibility.

[0004] 2. Negative pressure filtration method: This method uses a vacuum pump or suction device to generate negative pressure below the extraction column, driving the liquid to flow downwards. Although this method can process multiple columns simultaneously, the accuracy of negative pressure control is low, the flow rate fluctuates greatly, and the vacuum system is bulky and expensive, making it unsuitable for small laboratories or rapid on-site testing scenarios.

[0005] 3. Manual pressure application using a rubber syringe bulb: Positive pressure is applied to the extraction column by squeezing a rubber syringe bulb. This method is simple to operate, but it has the following problems: the rubber bulb may release organic pollutants such as plasticizers, interfering with the analysis of the target analyte; the pressure intensity depends entirely on manual feel and cannot be quantitatively controlled, leading to unreliable experimental results.

[0006] In summary, existing pressurization technologies all suffer from problems such as poor sealing, low pressure control accuracy, complex operation, or high risk of contamination, making it difficult to meet the requirements of solid-phase extraction for high efficiency, stability, and no contamination. Therefore, developing an auxiliary booster device that is simple in structure, reliably sealed, and contamination-free is of significant practical importance. Utility Model Content

[0007] Based on the problems existing in the above-mentioned background technology, this utility model proposes an auxiliary booster device for solid phase extraction columns, which solves the problems of poor sealing, low pressure control accuracy, complex operation and high risk of contamination that exist in existing pressurization technologies.

[0008] To achieve the above-mentioned objectives, the technical solution adopted by this utility model is as follows: This utility model provides an auxiliary booster device for a solid phase extraction column, which includes a push rod. A silicone piston head is provided at the bottom end of the push rod. The silicone piston head has a frustum structure that is larger at the top and smaller at the bottom. The top middle position of the silicone piston head is detachably connected to the bottom end of the push rod. Multiple sealing rings are provided on the outer circumference of the silicone piston head along its axial direction.

[0009] The working principle of an auxiliary booster device for a solid-phase extraction (SPE) column is as follows: The user vertically inserts the silicone piston head into the upper opening of the SPE column and manually presses down the push rod. The silicone piston head forms a one-way seal with the inner wall of the column through a tight fit, and multiple sealing rings further improve the sealing performance between the silicone piston head and the inner wall of the SPE column. This applies a uniform and stable linear pressure to the liquid inside the SPE column, driving the blockage liquid or eluent through the adsorbent layer, reducing the risk of poor sealing leading to uneven pressure and impurity contamination. The silicone piston head has a frustum-shaped structure, wider at the top and narrower at the bottom, facilitating its entry into the upper opening of the SPE column. The silicone piston head and push rod are detachably connected, which not only facilitates cleaning or replacement of the silicone piston head but also allows for compatibility with different specifications of SPE columns.

[0010] Furthermore, as a specific detachable connection between the silicone piston head and the push rod, the bottom end of the push rod is provided with an external thread, and the top center of the silicone piston head is provided with a connecting hole, the connecting hole being provided with an internal thread that connects with the external thread. The threaded connection between the silicone piston head and the push rod ensures a stable connection and facilitates disassembly.

[0011] Furthermore, as a specific arrangement of multiple sealing rings on the outer circumference of the silicone piston head, three sealing rings are evenly spaced along the axial direction on the outer circumference of the silicone piston head. Each sealing ring is parallel to each other, with a protrusion height of 0.1 mm and a width of 0.5 mm. This arrangement ensures that each sealing ring forms an interference fit with the inner wall of the extraction column, enhancing the sealing between the silicone piston head and the inner wall of the column, preventing liquid backflow during pressurization, ensuring pressure stability, and reducing liquid splashing.

[0012] Furthermore, as a specific configuration of the frustum structure, the silicone piston head has a top diameter and a bottom diameter difference of 0.5 mm.

[0013] Furthermore, the push rod segment is provided with scale markings along its axial direction, and the smallest scale division is 5 mm. The scale markings facilitate the user to accurately control the pressing depth according to the scale.

[0014] Furthermore, a push plate is provided at the top of the push rod, and the upper surface of the push plate is provided with a knurled anti-slip texture. The push plate facilitates the user to press down the push rod, thereby precisely controlling the pressing depth. The knurled anti-slip texture increases the friction between the push plate and the user's fingers, preventing slippage during the pressing process.

[0015] Compared with existing pressurization technologies, the beneficial effects of this invention are: This utility model provides an auxiliary booster device for a solid-phase extraction column. It features a simple structure, convenient operation, and low risk of contamination. The strong seal between the silicone piston head and the inner wall of the column applies uniform and stable linear pressure to the liquid inside the solid-phase extraction column, driving the blockage liquid or eluent through the adsorbent layer. This reduces the risk of poor sealing leading to uneven pressure and contamination. Simultaneously, the push rod is equipped with graduation marks, allowing users to precisely control the pressing depth according to the scale. This solves the problems of poor sealing, low pressure control accuracy, complex operation, and high risk of contamination inherent in existing pressurization technologies. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly described below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. The above and other objects, features, and advantages of this utility model will become clearer through the drawings. The same reference numerals indicate the same parts in all the drawings. The drawings are not intentionally drawn to scale to actual dimensions; the focus is on illustrating the main idea of ​​this utility model.

[0017] Figure 1 This is a schematic diagram of the auxiliary booster device for a solid-phase extraction column proposed in this utility model.

[0018] Figure 2 This is a schematic diagram of the push rod and the silicone piston head.

[0019] The components include: 1. push rod; 2. silicone piston head; 3. sealing ring; 4. external thread; 5. connecting hole; 6. internal thread; 7. scale marking; and 8. push plate. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can typically be arranged and designed in various different configurations.

[0021] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0022] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0023] Please refer to Figures 1-2 As shown, this utility model provides an auxiliary booster device for a solid-phase extraction column, which includes a push rod 1. A silicone piston head 2 is provided at the bottom end of the push rod 1. The silicone piston head 2 has a frustum structure, wider at the top and narrower at the bottom. Specifically, the silicone piston head 2 is made of medical-grade silicone rubber with a Shore A hardness of 50-70. A hardness of 50 Shore A is suitable for low-pressure scenarios, such as ≤30 kPa, where the silicone piston head 2 has a large deformation capacity, ensuring airtightness. A hardness of 70 Shore A is suitable for high-pressure scenarios, such as 30-100 kPa, where the silicone piston head 2 has strong resistance to compression, avoiding leakage caused by permanent deformation after long-term use. In actual manufacturing, the appropriate device can be selected flexibly according to needs.

[0024] The top center of the silicone piston head 2 is detachably connected to the bottom end of the push rod 1. Specifically, as a detachable connection between the silicone piston head 2 and the push rod 1, the bottom end of the push rod 1 is provided with an external thread 4, and the top center of the silicone piston head 2 is provided with a connecting hole 5. The connecting hole 5 is provided with an internal thread 6 that is threadedly connected to the external thread 4. The silicone piston head 2 and the push rod 1 are connected by a thread, which makes the connection between the silicone piston head 2 and the push rod 1 stable and easy to disassemble.

[0025] Multiple sealing rings 3 are arranged along the axial direction on the outer circumferential wall of the silicone piston head 2. As a specific arrangement of the multiple sealing rings 3 on the outer circumferential wall of the silicone piston head 2, three sealing rings 3 are evenly spaced along the axial direction on the outer circumferential wall of the silicone piston head 2. Each sealing ring 3 is parallel to each other, with a protrusion height of 0.1 mm and a width of 0.5 mm. This arrangement ensures that each sealing ring 3 forms an interference fit with the inner wall of the extraction column, enhancing the sealing between the silicone piston head 2 and the inner wall of the column, preventing liquid backflow during pressurization, ensuring pressure stability, and reducing liquid splashing.

[0026] Preferably, but not limited to, the push rod 1 has a scale mark 7 along its axial direction, and the smallest scale mark 7 is 5 mm. The scale mark 7 allows the user to accurately control the pressing depth according to the scale. The top of the push rod 1 is provided with a push plate 8, and the upper surface of the push plate 8 is provided with a knurled anti-slip texture. The push plate 8 allows the user to press down the push rod 1 by the push plate 8, thereby accurately controlling the pressing depth. The knurled anti-slip texture can increase the friction between the push plate 8 and the user's fingers, preventing slippage during the pressing process.

[0027] When using the auxiliary booster device for the solid-phase extraction column, the user vertically inserts the silicone piston head 2 into the upper opening of the solid-phase extraction column and manually presses down the push rod 1. The silicone piston head 2 forms a one-way seal through its tight fit with the inner wall of the column. The multiple sealing rings 3 are interference-fitted with the inner wall of the solid-phase extraction column, further improving the sealing performance. The user controls the pressing depth according to the scale markings 7, thereby applying a uniform and stable linear pressure to the liquid inside the solid-phase extraction column, driving the blockage liquid or eluent through the adsorbent layer. After use, the silicone piston head 2 can be disassembled for cleaning.

[0028] In summary, the auxiliary booster device for a solid-phase extraction column provided by this utility model has a simple structure, is easy to operate, and has a low risk of contamination. The strong seal between the silicone piston head 2 and the inner wall of the column applies uniform and stable linear pressure to the liquid inside the solid-phase extraction column, driving the blockage liquid or eluent through the adsorbent layer, reducing the risk of poor sealing leading to uneven pressure and impurity contamination. At the same time, the push rod 1 is equipped with a scale mark 7, which makes it easy for the user to accurately control the pressing depth according to the scale, solving the problems of poor sealing, low pressure control accuracy, complex operation, and high risk of contamination that exist in existing pressurization technologies.

[0029] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. An auxiliary booster device for a solid-phase extraction column, characterized in that, The device includes a push rod, the bottom of which is provided with a silicone piston head. The silicone piston head has a frustum structure that is larger at the top and smaller at the bottom. The top center of the silicone piston head is detachably connected to the bottom of the push rod. Multiple sealing rings are provided on the outer circumference of the silicone piston head along its axial direction.

2. The auxiliary booster device for the solid-phase extraction column according to claim 1, characterized in that, The bottom end of the push rod is provided with an external thread, and the top center of the silicone piston head is provided with a connecting hole, and the connecting hole is provided with an internal thread that is threadedly connected to the external thread.

3. The auxiliary booster device for the solid-phase extraction column according to claim 1, characterized in that, The silicone piston head has three sealing rings evenly spaced along its axial direction on its outer circumferential wall. Each sealing ring is parallel to each other, with a protrusion height of 0.1 mm and a width of 0.5 mm. Each sealing ring forms an interference fit with the inner wall of the extraction column.

4. The auxiliary booster device for the solid-phase extraction column according to claim 1, characterized in that, The difference between the top diameter and the bottom diameter of the silicone piston head is 0.5 mm.

5. The auxiliary booster device for the solid-phase extraction column according to claim 4, characterized in that, The push rod has a scale mark along its axial direction on its segment, and the smallest scale mark is 5 mm.

6. The auxiliary booster device for the solid-phase extraction column according to claim 1, characterized in that, The push rod is provided with a push plate at its top end, and the upper surface of the push plate is provided with a knurled anti-slip texture.

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