A separating device for vaccine adjuvant production

Abstract

The utility model belongs to vaccine adjuvant production technical field, concretely is a kind of separating device for vaccine adjuvant production, including separating bucket, separating mechanism is arranged on the separating bucket, separating mechanism includes: separating assembly, separating assembly includes the fixed ring of fixed connection on separating bucket inner wall, rotating ring is rotatably connected on the inner circular wall of fixed ring by annular groove, the first circular block is connected on the inner circular wall of rotating ring by clamping component, rotating rod is fixedly connected in the first circular block bottom, a group of filter screen is fixedly connected on rotating rod, rectangular rod is fixedly connected in the rotating rod bottom, to solve the significant problem existing in cleaning and maintenance, the internal structure of these separating devices is complicated and time-consuming in cleaning process, especially when processing the adjuvant containing biological active substance, residual material can cause cross-contamination to subsequent production batch, affect product quality.

Description

Technical Field

[0001] This utility model belongs to the field of vaccine adjuvant production technology, specifically a separation device for vaccine adjuvant production. Background Technology

[0002] Vaccine adjuvants are substances added to vaccines primarily to enhance their immunogenicity, that is, to increase the body's immune response to vaccine antigens. They themselves are usually not immunogenic, but they stimulate the body's immune system, making the antigens more easily recognized and processed by immune cells, thereby producing a stronger and more lasting immune response. In the production of vaccine adjuvants, separation technology is a crucial step in ensuring the purity and activity of the adjuvants.

[0003] In the existing technology, there are significant problems with cleaning and maintenance. The cleaning process of the internal structure of these separation devices is cumbersome and time-consuming, especially when dealing with adjuvants containing bioactive substances. The residual substances may cause cross-contamination to subsequent production batches, affecting product quality.

[0004] Therefore, this utility model provides a separation device for vaccine adjuvant production. Utility Model Content

[0005] To address the shortcomings of existing technologies and solve significant problems in cleaning and maintenance, the internal cleaning process of these separation devices is cumbersome and time-consuming, especially when dealing with adjuvants containing bioactive substances. Residual substances may cause cross-contamination in subsequent production batches, affecting product quality.

[0006] The technical solution adopted by this utility model to solve its technical problem is as follows: A separation device for vaccine adjuvant production, comprising a separation tank, wherein a separation mechanism is provided on the separation tank, and the separation mechanism includes:

[0007] A separation assembly includes a fixed ring fixed to the inner wall of a separation tank, a rotating ring rotatably connected to the inner circular wall of the fixed ring via an annular groove, a first circular block connected to the inner circular wall of the rotating ring via a locking assembly, a rotating rod fixed to the bottom of the first circular block, a set of filter screens fixed to the rotating rod, and a rectangular rod fixed to the bottom of the rotating rod.

[0008] A drive assembly, located at the bottom of the separation tank, is used to rotate the rectangular rod.

[0009] Release component, set at the bottom of the first circular block for releasing the first circular block.

[0010] Preferably, the drive assembly includes a motor fixed to the bottom of the separation tank by a pair of L-shaped rods, the output end of the motor is provided with a drive rod, and the drive rod is rotatably connected to the bottom of the separation tank and penetrates the bottom wall of the separation tank, and the top of the drive rod is provided with a placement groove.

[0011] Preferably, the positioning component includes a set of first grooves formed on the first circular block, the bottom of the first groove is fixed to the positioning block by a spring, and the positioning block is slidably connected in the first groove, and a set of positioning slots are formed on the inner circular wall of the rotating ring.

[0012] Preferably, the release assembly includes a set of guide rods fixed to the top of a first circular block, a second circular block slidably connected to the set of guide rods, and a handle fixed to the top of the second circular block.

[0013] Preferably, a set of first concave blocks are fixed to the bottom of the second circular block, and a connecting rod is rotatably connected between the opposite sidewalls of the first concave blocks via a first rotating shaft.

[0014] Preferably, the top of the first circular block is provided with a set of rectangular through slots, the top of the locking block is fixedly connected to a second concave block, and the end of the connecting rod away from the first concave block is rotatably connected between the opposite sidewalls of the second concave block through a second rotating shaft.

[0015] The beneficial effects of this utility model are as follows:

[0016] 1. The separation device for vaccine adjuvant production described in this utility model can be fixed in position by a first circular block under the fixing component, and the first circular block can be released by a release component to remove the rotating rod and a set of filter screens for cleaning. This solves the significant problems in cleaning and maintenance in the prior art. The internal structure cleaning process of these separation devices is cumbersome and time-consuming. Especially when dealing with adjuvants containing bioactive substances, residual substances may cause cross-contamination to subsequent production batches, affecting product quality. In addition, the aperture size of each layer of screen decreases sequentially, improving the separation effect.

[0017] 2. The separation device for vaccine adjuvant production described in this utility model allows the second circular block to move upward via a set of guide rods when the operator pulls the handle upward. This, connected by a connecting rod, enables the first concave block to pull the second concave block, causing the locking block to retract and move out of the locking groove. This releases the first circular block, allowing the rotating rod to be pulled out of the placement groove. The rotating rod and filter screen can then be removed for cleaning. The device allows for quick removal of the rotating rod, is simple to operate, and improves cleaning efficiency. Attached Figure Description

[0018] The present invention will be further described below with reference to the accompanying drawings.

[0019] Figure 1 This is a perspective view of the present invention;

[0020] Figure 2 This is a cross-sectional view of the separation bucket in this utility model;

[0021] Figure 3 This is a schematic diagram of the drive rod in this utility model;

[0022] Figure 4 This is a sectional view of the fixing ring in this utility model;

[0023] In the diagram: 1. Separating bucket; 2. Fixing ring; 3. Rotating ring; 4. First circular block; 5. Rotating rod; 6. Rectangular rod; 7. Motor; 8. Drive rod; 9. Placement slot; 10. First groove; 11. Spring; 12. Locking block; 13. Locking groove; 14. Guide rod; 15. Second circular block; 16. Handle; 17. First concave block; 18. Connecting rod; 19. Rectangular through groove; 20. Second concave block. Detailed Implementation

[0024] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0025] like Figures 1 to 4 As shown in the figure, a separation device for vaccine adjuvant production according to an embodiment of the present invention includes a separation tank 1, on which a separation mechanism is provided. The separation mechanism includes: a separation component, which includes a fixed ring 2 fixedly attached to the inner wall of the separation tank 1, a rotating ring 3 rotatably connected to the inner circular wall of the fixed ring 2 through an annular groove, a first circular block 4 connected to the inner circular wall of the rotating ring 3 through a locking component, a rotating rod 5 fixedly attached to the bottom of the first circular block 4, a set of filter screens fixedly attached to the rotating rod 5, and a rectangular rod 6 fixedly attached to the bottom of the rotating rod 5; a driving component, which is provided at the bottom of the separation tank 1 for driving the rectangular rod 6 to rotate; and a release component, which is provided at the bottom of the first circular block 4 for releasing the first circular block 4.

[0026] During operation, the first circular block 4 is fixed in position by the locking component, and the first circular block 4 can be released by the release component to remove the rotating rod 5 and a set of filter screens for cleaning. This solves the significant problems in cleaning and maintenance in the existing technology. The internal cleaning process of these separation devices is cumbersome and time-consuming, especially when dealing with adjuvants containing bioactive substances. The residual substances may cause cross-contamination to subsequent production batches, affecting product quality. In addition, the aperture size of each screen decreases sequentially, improving the separation effect.

[0027] The drive assembly includes a motor 7 fixed to the bottom of the separation tank 1 by a pair of L-shaped rods. The output end of the motor 7 is provided with a drive rod 8, which is rotatably connected to the bottom of the separation tank 1 and passes through the inner bottom wall of the separation tank 1. A placement groove 9 is provided on the top of the drive rod 8.

[0028] During operation, the motor 7 drives the drive rod 8 to rotate. The rotating rod 5, which is fixed with the rectangular rod 6, can be placed in the placement slot 9. This allows for limiting the rotation and makes the rotating rod 5 rotate simultaneously with the drive rod 8, making it convenient for staff to remove the rotating rod 5.

[0029] The positioning assembly includes a set of first grooves 10 opened on the first circular block 4. The bottom of the first groove 10 is fixed to the positioning block 12 by a spring 11, and the positioning block 12 is slidably connected in the first groove 10. A set of positioning grooves 13 are opened on the inner circular wall of the rotating ring 3.

[0030] During operation, the first circular block 4 can be fixed in position by locking the locking block 12 into the locking groove 13, and fixed to the rotating ring 3. The rotating ring 3 rotates on the inner circular wall of the fixed ring 2, which does not affect the rotation of the rotating rod 5.

[0031] The release assembly includes a set of guide rods 14 fixed to the top of the first circular block 4, a second circular block 15 slidably connected to the set of guide rods 14, and a handle 16 fixed to the top of the second circular block 15.

[0032] A set of first concave blocks 17 are fixed to the bottom of the second circular block 15, and a connecting rod 18 is rotatably connected between the opposite sidewalls of the first concave blocks 17 via a first rotating shaft.

[0033] The top of the first circular block 4 has a set of rectangular through slots 19, the top of the locking block 12 is fixedly connected to the second concave block 20, and the end of the connecting rod 18 away from the first concave block 17 is rotatably connected between the opposite side walls of the second concave block 20 through the second rotating shaft.

[0034] During operation, by pulling the handle 16 upwards, the second circular block 15 can be moved upwards by a set of guide rods 14. Through the connection of the connecting rod 18, the first concave block 17 can pull the second concave block 20 to move, thereby causing the locking block 12 to retract and move the locking block 12 out of the locking groove 13, releasing the first circular block 4. This allows the rotating rod 5 to be pulled out of the placement groove 9, and the rotating rod 5 and filter screen can be removed for cleaning. The rotating rod 5 can be removed quickly, the operation is simple, and the cleaning efficiency is improved.

[0035] Working principle: The first circular block 4 is fixed in position by the locking component, and the first circular block 4 can be released by the release component, so that the rotating rod 5 and a set of filter screens can be removed for cleaning. This solves the significant problems in cleaning and maintenance in the existing technology. The internal structure cleaning process of these separation devices is cumbersome and time-consuming, especially when dealing with adjuvants containing bioactive substances. The residual substances may cause cross-contamination to subsequent production batches, affecting product quality. In addition, the pore size of each screen decreases sequentially, which improves the separation effect.

[0036] The motor 7 drives the drive rod 8 to rotate. The rotating rod 5, which is fixed with the rectangular rod 6, can be placed in the placement slot 9. The rotation rod 5 can be limited and rotated simultaneously with the drive rod 8, making it convenient for staff to take out the rotating rod 5.

[0037] By locking the first circular block 4 into the locking groove 13 using the locking block 12, the position of the first circular block 4 can be fixed and fixed to the rotating ring 3. The rotating ring 3 rotates on the inner wall of the fixed ring 2, which does not affect the rotation of the rotating rod 5.

[0038] By having the operator pull the handle 16 upwards, the second circular block 15 can be moved upwards by a set of guide rods 14. Through the connection of the connecting rod 18, the first concave block 17 can pull the second concave block 20 to move, thereby causing the locking block 12 to retract and move the locking block 12 out of the locking groove 13, releasing the first circular block 4. This allows the rotating rod 5 to be pulled out of the placement groove 9, and the rotating rod 5 and filter screen can be removed for cleaning. The rotating rod 5 can be removed quickly, the operation is simple, and the cleaning efficiency is improved.

[0039] The terms "front," "back," "left," "right," "top," and "bottom" all refer to the figures in the accompanying drawings. Figure 1 Based on the perspective of the observer, the side of the device facing the observer is defined as the front, the left side of the observer is defined as the left, and so on.

[0040] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the scope of protection of this utility model.

[0041] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A separation device for vaccine adjuvant production, comprising a separation tank (1), characterized in that: The separation tank (1) is provided with a separation mechanism, which includes: The separation assembly includes a fixed ring (2) fixed to the inner wall of the separation barrel (1), a rotating ring (3) rotatably connected to the inner circular wall of the fixed ring (2) through an annular groove, a first circular block (4) connected to the inner circular wall of the rotating ring (3) through a locking assembly, a rotating rod (5) fixed to the bottom of the first circular block (4), a set of filter screens fixed to the rotating rod (5), and a rectangular rod (6) fixed to the bottom of the rotating rod (5). A drive assembly is located at the bottom of the separation barrel (1) to drive the rectangular rod (6) to rotate; A release component is provided at the bottom of the first circular block (4) for releasing the first circular block (4).

2. The separation device for vaccine adjuvant production according to claim 1, characterized in that: The drive assembly includes a motor (7) fixed to the bottom of the separation barrel (1) by a pair of L-shaped rods. The output end of the motor (7) is provided with a drive rod (8), which is rotatably connected to the bottom of the separation barrel (1) and penetrates the inner bottom wall of the separation barrel (1). The top of the drive rod (8) is provided with a placement groove (9).

3. The separation device for vaccine adjuvant production according to claim 1, characterized in that: The positioning assembly includes a set of first grooves (10) opened on the first circular block (4), the bottom of the first groove (10) is fixed to the positioning block (12) by a spring (11), and the positioning block (12) is slidably connected in the first groove (10). A set of positioning grooves (13) are opened on the inner circular wall of the rotating ring (3).

4. The separation device for vaccine adjuvant production according to claim 3, characterized in that: The release assembly includes a set of guide rods (14) fixed to the top of a first circular block (4), a second circular block (15) slidably connected to the set of guide rods (14), and a handle (16) fixed to the top of the second circular block (15).

5. The separation device for vaccine adjuvant production according to claim 4, characterized in that: The bottom of the second circular block (15) is fixed with a set of first concave blocks (17), and the first concave blocks (17) are rotatably connected to each other via a first rotating shaft by a connecting rod (18).

6. The separation device for vaccine adjuvant production according to claim 5, characterized in that: The first circular block (4) has a set of rectangular through slots (19) on its top. The second concave block (20) is fixedly connected to the top of the locking block (12). The end of the connecting rod (18) away from the first concave block (17) is rotatably connected between the opposite side walls of the second concave block (20) through the second rotating shaft.

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