A device for concentrating vaccine antigens

Abstract

The utility model discloses a kind of fixing devices of vaccine antigen concentration, it includes: rotating motor, the output end of the rotating motor is fixedly connected with rotating fixed platform, the outer surface of the rotating fixed platform is fixedly connected with ultrafiltration membrane assembly container, the outer surface of the rotating motor is fixedly connected with outside wear -resisting guide slide, the outer surface sliding connection of the outside wear -resisting guide slide has tooth linear guide rail, the outer surface sliding connection of another end of the tooth linear guide rail has inside wear -resisting guide slide, the outer surface fixedly connected with up-down moving motor of the inside wear -resisting guide slide;The inside of the heat preservation shell is provided with dustless concentration room, the outer surface of the other end of the arc support beam is respectively fixedly connected with humidifier and controllable heater;By cooperation of above component, realize device position flexible adjustment, it is also convenient to load and unload raw material, realize component flexible adjustment angle and position, to improve the effect of concentration efficiency.

Description

Technical Field

[0001] This utility model relates to the field of vaccine production technology, and in particular to a fixation device for concentrating vaccine antigens. Background Technology

[0002] A fixation device for vaccine antigen concentration is disclosed. This device is used to fix related equipment, such as ultrafiltration membrane modules and centrifuge tubes, during the vaccine antigen concentration process to prevent them from shifting or shaking under pressure and centrifugal force, ensuring a stable concentration environment, ensuring the precise flow path of the antigen solution, improving concentration efficiency and antigen activity retention rate, and providing a stable operating basis for the antigen purification and concentration process in vaccine production.

[0003] An existing device for concentrating vaccine antigens uses centrifuge tubes for concentration. However, it does not take into account the need for flexible addition and removal of raw materials, nor does it consider the need for the device to be repositioned to adapt to the humidity and temperature requirements of the raw materials, which seriously affects the effectiveness of the treatment. Utility Model Content

[0004] The purpose of this utility model is to at least solve one of the technical problems existing in the prior art, and to provide a fixation device for vaccine antigen concentration. It aims to improve the technical problems of existing fixation devices for vaccine antigen concentration that do not take into account the need for flexible addition and removal of raw materials during the concentration process, and also fail to consider the need for the fixation device to flexibly change position according to the requirements of the raw materials to adapt to the humidity and temperature required by the raw materials.

[0005] This utility model also provides a fixed device for concentrating vaccine antigens as described above, comprising: a rotary motor, the output end of which is fixedly connected to a rotary fixing platform; an ultrafiltration membrane module container is fixedly connected to the outer surface of the rotary fixing platform; the ultrafiltration membrane module container is pressure-driven, causing the feed liquid to flow through the membrane module, retaining large molecules and allowing small molecules to pass through, thus achieving separation and concentration (this method is prior art); an outer wear-resistant guide slider is fixedly connected to the outer surface of the rotary motor; a toothed linear guide rail is slidably connected to the outer surface of the outer wear-resistant guide slider; an inner wear-resistant guide slider is slidably connected to the outer surface of the other end of the toothed linear guide rail; a vertical moving motor is fixedly connected to the outer surface of the inner wear-resistant guide slider; and the output end of the vertical moving motor passes through the inner wear-resistant guide slider. Through the coordinated use of these components, the device position can be flexibly adjusted, facilitating the loading and unloading of raw materials. Simultaneously, the components can be flexibly adjusted in angle and position according to the amount of raw material loaded, thereby improving the concentration efficiency.

[0006] According to the present invention, a fixing device for concentrating vaccine antigens includes a gear fixedly connected to the output end of an up-and-down moving motor. A toothed linear guide rail meshes with the side surface of the gear. A limit pin passes through the inner surface of the toothed linear guide rail. An outer wear-resistant guide slider is rotatably connected to the outer surface of the gear. An arc-shaped support beam passes through the interior of the toothed linear guide rail, and an insulation shell is fixedly connected to the outer surface of the arc-shaped support beam. Through the coordinated use of these components, the device achieves flexible angle adjustment.

[0007] According to the present invention, a fixed device for concentrating vaccine antigens includes a dust-free concentration chamber inside the insulated shell. A humidifier and a controllable heater are fixedly connected to the outer surface of the other end of the arc-shaped support beam. The controllable heater monitors the temperature and adjusts the heating power via a temperature control element to maintain the heated object at a set temperature. This method is existing technology. An inner heat-insulating explosion-proof plate is fixedly connected to the inner surface of the dust-free concentration chamber. A second door panel mounting hole is provided inside the inner heat-insulating explosion-proof plate. A sealing strip is tightly fitted to the side surface of the second door panel mounting hole, and a hinge is fixedly connected to the outer surface of the second door panel mounting hole. Through the coordinated use of these components, a stable and vibration-free operation of the device is achieved.

[0008] According to the present invention, a device for concentrating vaccine antigens is provided, wherein the interior of the heat-insulating shell has a door panel mounting hole, a hinge is fixedly connected to the outer surface of the door panel mounting hole, and a corrosion-resistant transparent door panel is fixedly connected to the inner surface of the other end of the hinge. Through the coordinated use of these components, the device facilitates observation of its internal state.

[0009] According to the present invention, a fixing device for concentrating vaccine antigens is provided, wherein a sealing strip is tightly fitted to the outer surface of the mounting through hole of the door panel, and a corrosion-resistant transparent door panel is tightly fitted to the outer surface of the sealing strip. Through the combined use of these components, the device achieves the effect of facilitating observation of its internal state.

[0010] According to the present invention, a fixing device for concentrating vaccine antigens includes an explosion-proof and corrosion-resistant transparent door panel fixedly connected to the inner surface of the other end of the hinge, and a sealing strip tightly fitted to the side surface of the explosion-proof and corrosion-resistant transparent door panel. Through the coordinated use of these components, the device achieves a safe and explosion-proof effect.

[0011] According to the vaccine antigen concentration fixing device provided in this utility model, the interior of the heat-insulating shell is provided with a first drainage hole and a second drainage hole. Through the coordinated use of these components, the effect of preventing water accumulation inside the device is achieved.

[0012] According to the present invention, a device for concentrating vaccine antigens is provided, in which a base is fixedly connected to the lower outer surface of the heat-insulating shell, and an anti-slip rubber pad is fixedly connected to the lower surface of the base. Through the coordinated use of these components, a stable and vibration-free operation of the device is achieved.

[0013] Beneficial effects Compared with existing technologies, this fixed device for vaccine antigen concentration loads raw materials into an ultrafiltration membrane assembly container during use. A pre-set position causes a vertical moving motor to reach a predetermined location, which in turn drives a rotating fixed platform to a suitable angle. Simultaneously, a humidifier provides heating, and drain holes one and two quickly vent moisture from the dust-free concentration chamber to the outside. This allows for flexible adjustment of the device's position, facilitating the loading and unloading of raw materials. Furthermore, the components can be flexibly adjusted in angle and position according to the amount of raw materials loaded, thereby improving concentration efficiency. Attached Figure Description

[0014] The present invention will be further described below with reference to the accompanying drawings and embodiments; Figure 1 This is a cross-sectional view of the fixation device for concentrating vaccine antigens in this practical application. Figure 2 This is a perspective view of the fixation device for concentrating vaccine antigens in this practical application; Figure 3 This is a cross-sectional view of the fixation device for concentrating vaccine antigens in this practical application. Figure 4 This is a left view of the fixation device for concentrating vaccine antigens in this practical application; Figure 5 This is a front view of the fixation device for concentrating vaccine antigens in this practical application.

[0015] Legend: 1. Rotating fixed platform; 2. Insulated shell; 3. Door panel mounting through hole one; 4. Inner wear-resistant guide slider; 5. Outer wear-resistant guide slider; 6. Sealing strip; 7. Hinge; 8. Door panel mounting through hole two; 9. Cleanroom concentration chamber; 10. Toothed linear guide rail; 11. Arc-shaped support beam; 12. Drain hole one; 13. Drain hole two; 14. Base; 15. Up and down moving motor; 16. Explosion-proof and corrosion-resistant transparent door panel; 17. Corrosion-resistant transparent door panel; 18. Humidifier; 19. Rotary motor; 20. Inner insulation and explosion-proof plate; 21. Controllable heater; 22. Gear; 23. Anti-slip rubber pad; 24. Limit pin; 25. Ultrafiltration membrane module container. Detailed Implementation

[0016] This section will describe in detail the specific embodiments of this utility model. Preferred embodiments of this utility model are shown in the accompanying drawings. The purpose of the drawings is to supplement the textual description with graphics, so that people can intuitively and vividly understand each technical feature and overall technical solution of this utility model, but they should not be construed as limiting the scope of protection of this utility model.

[0017] Reference Figure 1 , Figure 2 , Figure 3 and Figure 5 This utility model discloses a fixing device for concentrating vaccine antigens, comprising: a rotary motor 19, a rotary fixing platform 1 fixedly connected to the output end of the rotary motor 19, an ultrafiltration membrane assembly container 25 fixedly connected to the outer surface of the rotary fixing platform 1, an outer wear-resistant guide slider 5 fixedly connected to the outer surface of the rotary motor 19, a toothed linear guide rail 10 slidably connected to the outer surface of the outer wear-resistant guide slider 5, an inner wear-resistant guide slider 4 slidably connected to the outer surface of the other end of the toothed linear guide rail 10, a vertical moving motor 15 fixedly connected to the outer surface of the inner wear-resistant guide slider 4, an output end of the vertical moving motor 15 penetrating the inner wear-resistant guide slider 4, a gear 22 fixedly connected to the output end of the vertical moving motor 15, a toothed linear guide rail 10 meshing with the side surface of the gear 22, and a limit pin 24 penetrating the inner surface of the toothed linear guide rail 10. The outer surface of gear 22 is rotatably connected to an outer wear-resistant guide slider 5. An arc-shaped support beam 11 runs through the inside of the toothed linear guide rail 10. An insulation shell 2 is fixedly connected to the outer surface of the arc-shaped support beam 11. A dust-free concentration chamber 9 is set inside the insulation shell 2. A humidifier 18 and a controllable heater 21 are fixedly connected to the outer surface of the other end of the arc-shaped support beam 11. An inner insulation explosion-proof plate 20 is fixedly connected to the inner surface of the dust-free concentration chamber 9. A second door panel mounting through hole 8 is set inside the inner insulation explosion-proof plate 20. A sealing strip 6 is tightly fitted to the side surface of the second door panel mounting through hole 8. A hinge 7 is fixedly connected to the outer surface of the second door panel mounting through hole 8. A first door panel mounting through hole 3 is set inside the insulation shell 2. A hinge 7 is fixedly connected to the outer surface of the first door panel mounting through hole 3. A corrosion-resistant transparent door panel 17 is fixedly connected to the inner surface of the other end of the hinge 7. Specifically, during use, raw materials are loaded and unloaded through the ultrafiltration membrane module container 25, and the up-and-down moving motor 15 is moved to a predetermined position by a pre-set position. Then, the rotating motor 19 drives the rotating fixed platform 1 to a predetermined angle, and then the controllable heater 21 and humidifier 18 provide a suitable environment.

[0018] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4A sealing strip 6 is tightly attached to the outer surface of the door panel mounting through hole 3, and a corrosion-resistant transparent door panel 17 is tightly attached to the outer surface of the sealing strip 6; an explosion-proof and corrosion-resistant transparent door panel 16 is fixedly connected to the inner surface of the other end of the hinge 7, and a sealing strip 6 is tightly attached to the side surface of the explosion-proof and corrosion-resistant transparent door panel 16; a drainage hole 12 and a drainage hole 23 are provided inside the insulation shell 2; a base 14 is fixedly connected to the lower outer surface of the insulation shell 2, and an anti-slip rubber pad 23 is fixedly connected to the lower surface of the base 14; Specifically, when the device is in use, drain hole 12 and drain hole 23 can quickly conduct water vapor inside the cleanroom 9 to the outside, ensuring the dryness inside the cleanroom 9. Ultimately, this enables flexible adjustment of the device position, facilitating loading and unloading of raw materials. It also allows the components to flexibly adjust their angle and position according to the amount of raw materials loaded, thereby improving the concentration efficiency.

[0019] Working principle: During use, raw materials are loaded and unloaded through the ultrafiltration membrane module container 25. The up-and-down moving motor 15 moves to the predetermined position, and then the rotating motor 19 drives the rotating fixed platform 1 to the predetermined angle. The controllable heater 21 and humidifier 18 provide a suitable environment. The drain hole 12 and drain hole 23 can quickly conduct water vapor inside the dust-free concentration chamber 9 to the outside, ensuring the dryness of the dust-free concentration chamber 9. Finally, the position of the fixed device can be flexibly adjusted to facilitate loading and unloading of raw materials. At the same time, the components can be flexibly adjusted in angle and position according to the amount of raw materials loaded, thereby improving the concentration efficiency.

[0020] The embodiments of this utility model have been described in detail above with reference to the accompanying drawings. However, this utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of this utility model.

Claims

1. A fixation device for concentrating vaccine antigens, characterized in that, include: A rotary motor (19) is fixedly connected to a rotary fixed platform (1) at its output end. An ultrafiltration membrane assembly container (25) is fixedly connected to the outer surface of the rotary fixed platform (1). An outer wear-resistant guide slider (5) is fixedly connected to the outer surface of the rotary motor (19). A toothed linear guide rail (10) is slidably connected to the outer surface of the outer wear-resistant guide slider (5). An inner wear-resistant guide slider (4) is slidably connected to the outer surface of the other end of the toothed linear guide rail (10). An up-and-down moving motor (15) is fixedly connected to the outer surface of the inner wear-resistant guide slider (4). The output end of the up-and-down moving motor (15) passes through the inner wear-resistant guide slider (4).

2. The fixation device for vaccine antigen concentration according to claim 1, characterized in that, The output end of the up-and-down moving motor (15) is fixedly connected to a gear (22), the side surface of the gear (22) is meshed with a toothed linear guide rail (10), the inner surface of the toothed linear guide rail (10) is penetrated by a limit pin (24), the outer surface of the gear (22) is rotatably connected to an outer wear-resistant guide slider (5), the inside of the toothed linear guide rail (10) is penetrated by an arc-shaped support beam (11), and the outer surface of the arc-shaped support beam (11) is fixedly connected to a heat-insulating shell (2).

3. The fixation device for vaccine antigen concentration according to claim 2, characterized in that, The interior of the heat-insulating shell (2) is provided with a dust-free concentration chamber (9). The outer surface of the other end of the arc-shaped support beam (11) is fixedly connected to a humidifier (18) and a controllable heater (21). The inner surface of the dust-free concentration chamber (9) is fixedly connected to an inner heat-insulating explosion-proof plate (20). The interior of the inner heat-insulating explosion-proof plate (20) is provided with a second door panel mounting hole (8). The side surface of the second door panel mounting hole (8) is tightly fitted with a sealing strip (6). The outer surface of the second door panel mounting hole (8) is fixedly connected to a hinge (7).

4. The fixation device for vaccine antigen concentration according to claim 2, characterized in that, The interior of the heat-insulating shell (2) is provided with a door panel mounting through hole (3), and a hinge (7) is fixedly connected to the outer surface of the door panel mounting through hole (3). A corrosion-resistant transparent door panel (17) is fixedly connected to the inner surface of the other end of the hinge (7).

5. The fixation device for vaccine antigen concentration according to claim 4, characterized in that, A sealing strip (6) is tightly attached to the outer surface of the door panel mounting through hole 1 (3), and a corrosion-resistant transparent door panel (17) is tightly attached to the outer surface of the sealing strip (6).

6. The fixation device for vaccine antigen concentration according to claim 4, characterized in that, The other end of the hinge (7) is fixedly connected to an explosion-proof and corrosion-resistant transparent door panel (16), and the side surface of the explosion-proof and corrosion-resistant transparent door panel (16) is tightly fitted with a sealing strip (6).

7. The fixation device for vaccine antigen concentration according to claim 2, characterized in that, The interior of the heat-insulating shell (2) is provided with a drainage hole one (12) and a drainage hole two (13).

8. The fixation device for vaccine antigen concentration according to claim 2, characterized in that, A base (14) is fixedly connected to the lower outer surface of the heat-insulating shell (2), and an anti-slip rubber pad (23) is fixedly connected to the lower surface of the base (14).

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