An auxiliary device for bone marrow stripping

Abstract

The application relates to the technical field of biological experimental equipment, in particular to an auxiliary device for bone marrow stripping, which comprises a fixing base, a pressing cover and a cutting knife. The fixing base is provided with a first arc-shaped groove; one end of the pressing cover is hingedly installed on the fixing base; and the first arc-shaped groove of the fixing base is provided with the cutting knife. In the application, the first arc-shaped groove on the fixing base can store and limit materials, so that the materials remain stable during cutting, the manual fixing step in the operation process is reduced, and the operation convenience is improved. The inner wall of the first arc-shaped groove limits the axial and radial displacement of the materials, ensures the stability of the materials during cutting, and thus improves the cutting accuracy. When the pressing cover is closed by rotating towards the fixing base, the materials can be extruded to move towards the cutting knife, so that the cutting process is smoother, and the cutting efficiency is improved.

Description

Technical Field

[0001] This application relates to the field of biological experimental equipment technology, and more specifically, to an auxiliary device for bone marrow removal. Background Technology

[0002] With the continuous development of the biomedical field, rabbit models are widely used due to their immune responses being similar to those of humans. Rabbit models offer unique advantages, especially in the preparation of monoclonal and polyclonal antibodies. In antibody preparation using rabbit models, bone marrow needs to be collected as research material. Currently, the main method is to surgically remove bone marrow from the rabbit model's leg. This involves first peeling away the surface tissue of the bone with a scalpel, and then using tools to extract the bone marrow. Specifically, the leg bone is usually crushed with forceps, and the bone marrow is carefully extracted piece by piece and placed in cryovials for cryopreservation in liquid nitrogen to ensure that the bone marrow's activity remains unaffected.

[0003] However, in practice, directly crushing bones with pliers is not only slow but also ineffective, often resulting in incomplete bone marrow removal and impacting subsequent research. Furthermore, manually operating a bone cutter is difficult to master, presenting both operational challenges and safety risks. Utility Model Content

[0004] The purpose of this application is to provide an auxiliary device for bone marrow removal that can improve the efficiency and quality of bone marrow extraction.

[0005] To achieve the above objectives, this utility model provides an auxiliary device for bone marrow removal, comprising:

[0006] A fixed base, wherein the fixed base is provided with a first arc-shaped groove for storing and limiting materials;

[0007] A pressing cover, one end of which is hinged to the fixed base, so that the pressing cover can be rotated open and closed on the fixed base. The first arc-shaped groove has an opening in the direction toward the pressing cover, so that when the pressing cover is rotated to close in the direction toward the fixed base, it can squeeze the material in the first arc-shaped groove.

[0008] The cutting blade is provided at the first arc-shaped groove of the fixed base. The material is squeezed by the pressing cover and moves towards the cutting blade in the first arc-shaped groove, and the cutting blade cuts the material.

[0009] In an optional implementation, it further includes:

[0010] A temperature-regulating base is provided on the fixed base to adjust the temperature of the fixed base, thereby adjusting the temperature of the material in the first arc-shaped groove.

[0011] In an optional embodiment, the temperature-regulating base is provided with a cooling chamber for storing the cooling medium.

[0012] In an optional embodiment, a heater is provided on the temperature-regulating base.

[0013] In an optional implementation, it further includes:

[0014] The first inner liner plate is configured as a plate structure that adapts to the arc-shaped inner wall of the first arc-shaped groove. The first inner liner plate is disposed in the first arc-shaped groove to adjust the cavity size in the first arc-shaped groove, thereby adapting to materials of different sizes.

[0015] The cutting blade at the first arc-shaped groove is disposed on the inner wall of the first inner liner plate.

[0016] In an optional embodiment, at least two first inner lining plates are provided, and at least two of the first inner lining plates have different thicknesses. The first inner lining plates of different thicknesses are replaced in the first arc-shaped groove to adjust the cavity size in the first arc-shaped groove.

[0017] In an optional embodiment, the pressing cover is provided with a second arc-shaped groove, and a cutting blade is provided at the second arc-shaped groove of the pressing cover.

[0018] In an optional implementation, it further includes:

[0019] The second inner liner plate is configured as a plate structure that adapts to the arc-shaped inner wall of the second arc-shaped groove. The second inner liner plate is disposed in the second arc-shaped groove to adjust the cavity size in the second arc-shaped groove, thereby adapting to materials of different sizes.

[0020] The cutting blade at the second arc-shaped groove is disposed on the inner wall of the second inner liner plate.

[0021] In an optional embodiment, at least two second inner lining plates are provided, and at least two of the second inner lining plates have different thicknesses. The second inner lining plates of different thicknesses are replaced in the second arc-shaped groove to adjust the cavity size in the second arc-shaped groove.

[0022] In an optional implementation, it further includes:

[0023] A fixed handle is fixedly mounted on the pressing cover.

[0024] In this application, the first arc-shaped groove design on the fixed base can store and limit the material, keeping it stable during cutting, reducing manual fixing steps and improving operational convenience. The inner wall of the first arc-shaped groove restricts the axial and radial displacement of the material, ensuring its stability during cutting and thus improving cutting accuracy. When the pressure cover rotates to close towards the fixed base, it can compress the material, causing it to move towards the cutting blade. This design makes the cutting process smoother and improves cutting efficiency.

[0025] Other features and advantages of this application will be described in detail in the following detailed description section. Attached Figure Description

[0026] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0027] Figure 1 A schematic diagram of the structure from one perspective of one embodiment of an auxiliary device for bone marrow removal provided in this application;

[0028] Figure 2 This is a schematic diagram of the structure from one perspective of another embodiment of an auxiliary device for bone marrow removal provided in this application.

[0029] icon:

[0030] 100 - Fixed base; 110 - First inner lining plate; 120 - First arc-shaped groove; 130 - Stop;

[0031] 200 - Press-fit cap; 210 - Second inner liner plate; 220 - Second arc-shaped groove;

[0032] 300-cutting blade;

[0033] 400-Temperature Adjustable Base;

[0034] 500 - Fixed handle; 550 - Support component; 560 - Mating groove. Detailed Implementation

[0035] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0036] In the description of this application, it should be noted that the terms "inner" and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product is in use. They are used only for the convenience of describing this application and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0037] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "setup" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0038] Embodiments of this application provide an auxiliary device for bone marrow removal, used to cut the bones of experimental animals to extract the desired bone marrow; such as Figure 1 As shown, the bone marrow stripping auxiliary device includes a fixing base 100, a pressing cover 200, and a cutting blade 300.

[0039] The fixed base 100 is provided with a first arc-shaped groove 120 for storing and limiting materials.

[0040] For example, the material may be a rabbit, chicken bone, or mouse leg bone or spine. This application uses a rabbit leg bone as an example to illustrate the technical solution.

[0041] The inner wall of the first arc-shaped groove 120 restricts the axial and radial displacement of the material, making it convenient to cut the material.

[0042] One end of the pressing cover 200 is hinged to the fixed base 100, so that the pressing cover 200 can be rotated open and closed on the fixed base 100.

[0043] The first arc-shaped groove 120 has an opening in the direction of the pressing cover 200, so that when the pressing cover 200 is rotated and closed in the direction of the fixed base 100, the material in the first arc-shaped groove 120 can be squeezed.

[0044] A cutting blade 300 is provided at the first arc-shaped groove 120 of the fixed base 100. The material is squeezed by the pressing cover 200 and moves towards the cutting blade 300 in the first arc-shaped groove 120, where the cutting blade 300 cuts the material.

[0045] For example, multiple first arc-shaped grooves 120 are provided so that the pressing cap 200 can simultaneously squeeze multiple materials, thereby improving the efficiency of bone marrow extraction.

[0046] In this application, the first arc-shaped groove 120 on the fixed base 100 is designed to store and limit material, ensuring its stability during cutting, reducing manual fixing steps and improving operational convenience. The inner wall of the first arc-shaped groove 120 restricts the axial and radial displacement of the material, ensuring its stability during cutting and thus improving cutting accuracy. When the pressure cover 200 rotates and closes towards the fixed base 100, it compresses the material, causing it to move towards the cutting blade 300. This design makes the cutting process smoother and improves cutting efficiency.

[0047] like Figure 1 As shown, in one embodiment, the auxiliary device for bone marrow removal also includes a temperature-regulating base 400, which is disposed on the fixed base 100 to regulate the temperature of the fixed base 100, thereby regulating the temperature of the material in the first arc-shaped groove 120.

[0048] For example, the temperature-regulating base 400 can heat or cool the fixed base 100. When materials need to be processed under constant temperature conditions and the temperature of the fixed base 100 is lower than the required temperature, the temperature-regulating base 400 can heat the fixed base 100. When materials need to be processed under low temperature conditions and the temperature of the fixed base 100 is higher than the required temperature, the temperature-regulating base 400 can cool the fixed base 100.

[0049] There are many ways for the temperature-controlled base 400 to heat the fixed base 100, such as resistance heating, electromagnetic heating, infrared heating, fuel heating, etc.

[0050] There are many ways to cool the fixed base 100 using the temperature-regulating base 400, such as air cooling, water cooling, or cooling by absorbing heat with ice.

[0051] For example, the temperature-regulating base 400 and the fixed base 100 can be connected in many ways. For instance, they can be detachably connected, with a groove on the end face of the temperature-regulating base 400 near the fixed base 100 for engaging the fixed base 100. The fixed base 100 engages in the groove of the temperature-regulating base 400 to achieve a detachable connection. Another example is that the temperature-regulating base 400 and the fixed base 100 can be detachably fixed together using bolts.

[0052] The temperature-regulating base 400 can adjust the temperature of the fixed base 100, thereby precisely controlling the temperature of the material within the first arc-shaped groove 120. This is crucial for bone marrow stripping operations that require specific temperature conditions, ensuring that the material is processed at the optimal temperature, thus improving bone marrow quality and stripping efficiency.

[0053] With its heating or cooling function, the temperature-controlled base 400 allows the device to adapt to bone marrow stripping operations with varying temperature requirements. Whether processing is required under constant temperature, high temperature, or low temperature conditions, the temperature-controlled base 400 can achieve this, enhancing the applicability and flexibility of the device.

[0054] In some cases, materials are sensitive to temperature; excessively high or low temperatures can cause deterioration or damage. The temperature-controlled base 400 can precisely control the temperature, preventing damage to materials due to improper temperature, thereby protecting the integrity and quality of the materials.

[0055] In one embodiment, the temperature-regulating base 400 is provided with a cooling chamber for storing a cooling medium. The cooling medium may be, for example, ice, an ice-water mixture, or cold air. The cooling medium can remain or flow within the cooling chamber.

[0056] In one embodiment, a heater is provided on the temperature-controlled base 400.

[0057] For example, the heater includes, but is not limited to: resistance heater, electromagnetic heater, infrared heater, fuel heater, etc.

[0058] like Figure 1 As shown, in one embodiment, the bone marrow removal aid also includes a first inner liner plate 110.

[0059] The first inner liner plate 110 is configured as a plate structure that adapts to the arc-shaped inner wall of the first arc-shaped groove 120. The first inner liner plate 110 is disposed in the first arc-shaped groove 120 to adjust the cavity size in the first arc-shaped groove 120, thereby adapting to materials of different sizes.

[0060] It should be understood that, in this embodiment, the inner wall of the first arc-shaped groove 120 is used to limit the displacement of the first inner liner plate 110, and the inner wall of the first inner liner plate 110 can replace the inner wall of the first arc-shaped groove 120 to limit the displacement of the material.

[0061] The cutting blade 300 at the first arc-shaped groove 120 is disposed on the inner wall of the first inner liner plate 110.

[0062] During use, if the material is small in size and is placed directly into the first arc-shaped groove 120, the pressing cover 200 cannot compress the material, preventing it from approaching the cutting blade 300. Consequently, the cutting blade 300 cannot cut the material, and the bone marrow cannot be obtained. To obtain the bone marrow, the first inner liner plate 110 needs to be installed in the first arc-shaped groove 120. Then, the material is placed in the groove of the first inner liner plate 110, the pressing cover 200 closes, and compresses the material. Under compression, the material moves into the first inner liner plate 110 and towards the cutting blade 300 within it, where the cutting blade 300 cuts the material.

[0063] For example, the first inner liner 110 is fixedly installed in the first arc-shaped groove 120.

[0064] For example, a stop 130 is provided at the end opening of the first arc-shaped groove 120. The stop 130 is used to stop the first inner liner 110 and prevent the first inner liner 110 from sliding out of the first arc-shaped groove 120. However, in another embodiment, the first inner liner 110 is detachably mounted on the inner wall of the first arc-shaped groove 120 by bolts.

[0065] For example, the cutting blade 300 is integrally formed with the first inner liner plate 110. In another embodiment, the inner wall of the first inner liner plate 110 is provided with a slot for engaging the cutting blade 300, and the cutting blade 300 is engaged in the slot of the first inner liner plate 110.

[0066] In this application, by providing a first inner liner plate 110 within the first arc-shaped groove 120, the cavity size within the groove can be adjusted to accommodate materials of different sizes. This design improves the versatility and flexibility of the device, enabling the same device to handle materials of various sizes.

[0067] In one embodiment, at least two first inner lining plates 110 are provided, and at least two different first inner lining plates 110 have different thicknesses. It should be understood that the inner wall of the first arc-shaped groove 120 matches the outer wall of the first inner lining plate 110. If more than two first arc-shaped grooves 120 are provided, and the inner wall dimensions of different first arc-shaped grooves 120 are the same, then the outer diameters of different first inner lining plates 110 are the same, while the inner diameters of first inner lining plates 110 with different thicknesses are different.

[0068] The cavity size within the first arc-shaped groove 120 is adjusted by replacing the first inner liner plate 110 of different thicknesses.

[0069] By providing at least two first inner liner plates 110 of different thicknesses, the user can easily adjust the cavity size within the first arcuate groove 120 as needed. This height adjustability allows the device to accommodate a wider variety of material sizes, improving its versatility and flexibility.

[0070] Since the first inner liner 110 is replaceable, users can quickly and easily replace the first inner liner 110 with different thicknesses as needed, without having to make complex adjustments or modifications to the entire device.

[0071] To further fit the shape of the material, and thus better limit and cut the material, such as Figure 1 As shown, in one embodiment, a second arc-shaped groove 220 is provided on the pressing cover 200, and a cutting blade 300 is provided at the second arc-shaped groove 220 of the pressing cover 200. When the pressing cover 200 rotates to close towards the fixed base 100, the arc-shaped inner wall of the second arc-shaped groove 220 limits the displacement of the material, and the cutting blade 300 provided in the second arc-shaped groove 220 on the pressing cover 200 cuts the material accordingly, improving the material cutting effect, making the rabbit leg bone fragmentation effect better, and thus improving the bone marrow extraction efficiency.

[0072] The second arc-shaped groove 220 on the pressing cover 200 can better fit the shape of the material, especially when the material (such as a rabbit leg bone) has a certain curvature or bend. This design allows the material to be placed more stably in the groove during the pressing process, reducing the possibility of displacement and slippage.

[0073] The cutting blade 300 is positioned within the second arc-shaped groove 220 of the pressing cover 200. When the pressing cover 200 is closed, the cutting blade 300 can cut the material accordingly. This design makes the contact between the cutting blade 300 and the material closer and more uniform, improving the cutting efficiency and effect, especially for materials that need to be crushed (such as rabbit leg bones), it can better achieve the crushing purpose.

[0074] like Figure 1 As shown, in one embodiment, the bone marrow stripping auxiliary device further includes a second inner liner plate 210, which is configured as a plate structure adapted to the arcuate inner wall of the second arcuate groove 220. The second inner liner plate 210 is disposed in the second arcuate groove 220 to adjust the cavity size within the second arcuate groove 220, thereby accommodating materials of different sizes.

[0075] The cutting blade 300 at the second arc-shaped groove 220 is disposed on the inner wall of the second inner liner 210. Exemplarily, the second inner liner 210 is detachably mounted on the inner wall of the second arc-shaped groove 220 by bolts.

[0076] For example, the cutting blade 300 is integrally formed with the second inner liner plate 210. In another embodiment, the inner wall of the second inner liner plate 210 is provided with a slot for engaging the cutting blade 300, and the cutting blade 300 is engaged in the slot of the second inner liner plate 210.

[0077] In one embodiment, at least two second inner liner plates 210 are provided, and the thickness of the different second inner liner plates 210 is different. The second inner liner plates 210 of different thicknesses are replaced in the second arc-shaped groove 220 to adjust the cavity size in the second arc-shaped groove 220.

[0078] It should be understood that the inner wall of the second arc-shaped groove 220 matches the outer wall of the second inner liner plate 210. If there are two or more second arc-shaped grooves 220, and the inner wall dimensions of different second arc-shaped grooves 220 are the same, then the outer diameters of different second inner liner plates 210 are the same, and the inner diameters of second inner liner plates 210 with different thicknesses are different.

[0079] like Figure 1 As shown, in one embodiment, the bone marrow stripping aid further includes a fixing handle 500, which is fixedly disposed on the pressing cover 200.

[0080] For example, the fixed handle 500 is fixedly mounted on the pressure cover 200 by means of welding, bolting, snap-fitting or integral molding.

[0081] The operator operates the rotating opening and closing of the pressing cover 200 by using the fixed handle 500.

[0082] like Figure 2 As shown, in one embodiment, a plurality of mating grooves 560 are provided on the end face of the fixed base 100 near the pressing cover 200.

[0083] The auxiliary device for bone marrow removal also includes a support 550, one end of which is hinged to the pressing cover 200, and the other end of which is hinged to the mating groove 560.

[0084] For example, the support member 550 is an L-shaped rod structure.

[0085] like Figure 2 As shown, the support member 550 supports the pressing cover 200 to remain open on the fixed base 100, making it convenient to add materials to the fixed base 100. The other end of the support member 550 is switched to engage with different mating grooves 560, so that the pressing cover 200 maintains different opening angles on the fixed base 100.

[0086] It should be noted that, where there is no conflict, the features in the embodiments of this application can be combined with each other.

[0087] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. An auxiliary device for bone marrow removal, characterized in that, include: A fixed base (100) is provided with a first arc-shaped groove (120) for storing and limiting materials; A pressing cover (200) is hinged at one end to the fixed base (100), so that the pressing cover (200) can rotate and open on the fixed base (100). The first arc-shaped groove (120) has an opening in the direction toward the pressing cover (200), so that when the pressing cover (200) rotates and closes toward the fixed base (100), it can squeeze the material in the first arc-shaped groove (120). The cutting blade (300) is provided at the first arc-shaped groove (120) of the fixed base (100). The material is squeezed by the pressing cover (200) and moves towards the cutting blade (300) in the first arc-shaped groove (120). The cutting blade (300) cuts the material.

2. The auxiliary device for bone marrow removal according to claim 1, characterized in that, Also includes: Temperature regulating base (400) is disposed on the fixed base (100) to regulate the temperature of the fixed base (100), thereby regulating the temperature of the material in the first arc-shaped groove (120).

3. The auxiliary device for bone marrow removal according to claim 2, characterized in that, The temperature-regulating base (400) is provided with a cooling chamber for storing the cooling medium.

4. The auxiliary device for bone marrow removal according to claim 2, characterized in that, A heater is provided on the temperature-regulating base (400).

5. The auxiliary device for bone marrow removal according to claim 1, characterized in that, Also includes: The first inner lining plate (110) is configured as a plate structure that adapts to the arc-shaped inner wall of the first arc-shaped groove (120). The first inner lining plate (110) is disposed in the first arc-shaped groove (120) to adjust the cavity size in the first arc-shaped groove (120) so as to adapt to materials of different sizes. The cutting blade (300) at the first arc-shaped groove (120) is disposed on the inner wall of the first inner liner plate (110).

6. The auxiliary device for bone marrow removal according to claim 5, characterized in that, The number of the first inner liner (110) is at least two, and at least two of the first inner liner (110) have different thicknesses. The first inner liner (110) of different thicknesses is replaced in the first arc-shaped groove (120) to adjust the cavity size in the first arc-shaped groove (120).

7. The auxiliary device for bone marrow removal according to any one of claims 1 to 6, characterized in that, The pressing cover (200) is provided with a second arc-shaped groove (220), and a cutting blade (300) is provided at the second arc-shaped groove (220) of the pressing cover (200).

8. The auxiliary device for bone marrow removal according to claim 7, characterized in that, Also includes: The second inner lining plate (210) is configured as a plate structure that adapts to the arc-shaped inner wall of the second arc-shaped groove (220). The second inner lining plate (210) is disposed in the second arc-shaped groove (220) to adjust the cavity size in the second arc-shaped groove (220) so as to adapt to materials of different sizes. The cutting blade (300) at the second arc-shaped groove (220) is disposed on the inner wall of the second inner liner plate (210).

9. The auxiliary device for bone marrow removal according to claim 8, characterized in that, The number of the second inner liner (210) is at least two, and at least two of the second inner liner (210) have different thicknesses. The second inner liner (210) of different thicknesses is replaced in the second arc-shaped groove (220) to adjust the cavity size in the second arc-shaped groove (220).

10. The auxiliary device for bone marrow removal according to claim 1, characterized in that, Also includes: A fixed handle (500) is fixedly mounted on the pressing cover (200).

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