A biological sample storage device for storing stem cells

Abstract

The utility model discloses a biological sample storage equipment for storing stem cell relates to stem cell storage tool technical field, including refrigeration mechanism, including refrigeration cabinet body, refrigeration cabinet body inner wall fixedly connected with push rod, support mechanism is fixedly connected in the refrigeration cabinet body inner wall, including the fixed plate of fixedly connected in the refrigeration cabinet body inner wall, install the limiting piece on the fixed plate, the fixed plate one side is equipped with the docking groove, and, storage mechanism is installed on the fixed plate, including the placement board of inserting in the docking groove, the placement groove is equipped with in the placement board top, the placement groove is fixedly connected with air bag, the utility model discloses through the cooperation of storage mechanism under the support mechanism and push rod, can prevent in the equipment movement or vibration and easily lead to sample container displacement, collision even breakage, and the storage dish cover and container joint place are not easy to permeate cold air, and not easy to freeze and stick together, and the recovery is convenient to open.

Description

Technical Field

[0001] This utility model relates to the field of stem cell storage equipment technology, and in particular to a biological sample storage device for storing stem cells. Background Technology

[0002] Stem cells are a type of pluripotent cell with self-renewal capacity. They are undifferentiated and immature cells with the potential to regenerate various tissues, organs, and the human body. They are known in the medical field as "universal cells." After stem cells are isolated and cultured from different human tissues, they are tested and identified, and then cryopreserved at low temperatures so that they can be revived and reinfused into patients when needed in clinical practice to treat diseases. Stem cell biological sample storage refrigerators are professional low-temperature equipment designed for the long-term preservation of stem cell bioactivity. They slow down cell metabolism and degradation through precise temperature control and a stable environment.

[0003] However, in practical applications, there are still some unresolved problems. The following are some common problems of biological sample storage devices used to store stem cells: Traditional storage devices rely on simple snaps or gravity fixation, which can easily cause sample containers to shift, collide, or even break when the device is moved or vibrated. In addition, cold air can easily seep into the seam between the lid of the storage dish and the container, causing the inside to freeze and stick together, making it difficult to open during revival. Utility Model Content

[0004] In view of the problems existing in the above-mentioned biological sample storage devices for storing stem cells, this utility model is proposed.

[0005] Therefore, the problem to be solved by this utility model is how to solve the support of the triangular area.

[0006] To solve the above-mentioned technical problems, this utility model provides the following technical solution: a biological sample storage device for storing stem cells, comprising, A refrigeration mechanism, including a refrigerator body, wherein a push rod is fixedly connected to the inner wall of the refrigerator body; A support mechanism, fixedly connected to the inner wall of the refrigerator body, includes a fixing plate fixedly connected to the inner wall of the refrigerator body, a limiting component installed on the fixing plate, and a mating groove formed on one side of the fixing plate; and... The storage mechanism, mounted on a fixed plate, includes a placement plate inserted into a docking slot. The top of the placement plate has a placement groove, and an airbag is fixedly connected in the placement groove. An inflation component is installed on the placement plate and the airbag. An unlocking component and a driving component are respectively installed on the placement plate.

[0007] As a preferred embodiment of the biological sample storage device for storing stem cells according to the present invention, the limiting member includes a groove formed in the fixing plate, a locking block is slidably connected in the groove, and a first spring is fixedly connected between the surface of the locking block and the inner wall of the groove.

[0008] As a preferred embodiment of the biological sample storage device for storing stem cells according to the present invention, wherein: a first guide groove is provided on the inner wall of the groove, a first guide block is fixedly connected to the card block, and the card block is slidably connected in the first guide groove.

[0009] As a preferred embodiment of the biological sample storage device for storing stem cells described in this utility model, a rubber pad is fixedly connected to one end of the card block.

[0010] As a preferred embodiment of the biological sample storage device for storing stem cells according to the present invention, the inflator includes a short tube communicating with the surface of the air bladder, the placement plate has an elongated groove, a piston is slidably connected in the elongated groove, one end of the short tube is communicating with the air bladder, and one end of the push rod is inserted into the elongated groove and contacts the surface of the piston.

[0011] As a preferred embodiment of the biological sample storage device for storing stem cells described in this utility model, the piston surface is fitted with a sealing ring, and its surface is in contact with the inner wall of the long groove.

[0012] As a preferred embodiment of the biological sample storage device for storing stem cells according to the present invention, wherein: the unlocking component includes a slot formed in the placement plate, an unlocking plate is slidably connected in the slot, a second guide groove is formed in the inner wall of the slot, a second guide block is fixedly connected to the unlocking component and slidably connected in the second guide groove, a second spring is fixedly connected between the surface of the second guide block and the inner wall of the second guide groove, and one end of the locking block is inserted into the slot.

[0013] As a preferred embodiment of the biological sample storage device for storing stem cells according to the present invention, the driving component includes a rotating cylinder rotatably connected to a placement plate, a cam fixedly connected to one end of the rotating cylinder located in a slot, a groove being formed inside the rotating cylinder, a short rod slidably connected to the rotating cylinder, a round block being fixedly connected to one end of the short rod, a limiting post being fixedly connected to the round block, and a limiting groove cooperating with the limiting post being formed inside the groove.

[0014] As a preferred embodiment of the biological sample storage device for storing stem cells described in this utility model, a handle is fixedly connected to one end of the short rod, a third spring is sleeved on the surface of the short rod, and its two ends are in contact with the inner wall of the tank and the surface of the circular block, respectively.

[0015] As a preferred embodiment of the biological sample storage device for storing stem cells described in this utility model, the placement plate has a buffer groove on its side and a through hole on its top.

[0016] The beneficial effects of this utility model are as follows: with the cooperation of the support mechanism and the push rod, the storage mechanism can prevent the sample container from shifting, colliding or even breaking when the equipment is moved or vibrated. In addition, cold air is not easily seeped into the seam between the lid of the storage dish and the container, and it is not easy to freeze and stick. It is also easy to open during resuscitation. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of a biological sample storage device used to store stem cells.

[0019] Figure 2 This is a three-dimensional cross-sectional view of a biological sample storage device used for storing stem cells.

[0020] Figure 3 Biological sample storage devices for storing stem cells Figure 2 Enlarged structural diagram of A in the middle.

[0021] Figure 4 Biological sample storage devices for storing stem cells Figure 2 Enlarged structural diagram of B in the middle.

[0022] Figure 5 Biological sample storage devices for storing stem cells Figure 2 A magnified structural diagram of C.

[0023] Figure 6 A partial cross-sectional three-dimensional structural view of the drive component of a biological sample storage device used for storing stem cells.

[0024] Figure 7 This is a three-dimensional structural diagram of the placement plate of a biological sample storage device used to store stem cells.

[0025] In the diagram: 1. Refrigeration mechanism; 11. Refrigerator body; 12. Push rod; 2. Support mechanism; 21. Fixing plate; 22. Limiting component; 23. Connecting groove; 3. Storage mechanism; 31. Placement plate; 32. Placement slot; 33. Airbag; 34. Inflating component; 35. Unlocking component; 36. Driving component; 37. Buffer groove; 38. Through hole; 22-1. Groove; 22-2. Locking block; 22-3. First spring; 22-4. First guide groove; 22-5. First guide block; 22 -6. Rubber pad; 34-1. Short tube; 34-2. Long groove; 34-3. Piston; 34-4. Sealing ring; 35-1. Slot; 35-2. Unlocking plate; 35-3. Second guide groove; 35-4. Second guide block; 35-5. Second spring; 36-1. Rotary cylinder; 36-2. Cam; 36-3. Groove; 36-4. Short rod; 36-5. Round block; 36-6. Limiting post; 36-7. Limiting groove; 36-8. Handle; 36-9. Third spring. Detailed Implementation

[0026] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.

[0027] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Those skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0028] Secondly, the term "an embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that excludes other embodiments.

[0029] Example 1 Reference Figure 1 and Figure 2 This is the first embodiment of the present invention. This embodiment provides a biological sample storage device for storing stem cells. The biological sample storage device for storing stem cells includes a refrigeration mechanism 1, a support mechanism 2, and a storage mechanism 3. The support mechanism 2 can support, limit, and fix the storage mechanism 3. The storage mechanism 3 can prevent the sample container from shifting, colliding, or even breaking when the device is moved or vibrated. In addition, cold air is not easily seeped into the seam between the lid of the storage dish and the container.

[0030] Specifically, the refrigeration unit 1 includes a refrigerator body 11, which is a storage device for storing stem cells. This is existing technology, and the working principle of this part is also existing technology, which can be clearly understood by those skilled in the art, so it will not be described in detail here. It can meet the conditions for storing stem cell biological samples. A push rod 12 is fixedly connected to the inner wall of the refrigerator body 11. When it is mixed into the long groove 34-2, the push rod 12 can push the piston 34-3 to move, so as to inflate the air bag 33, fix the storage dish and seal the lid seam.

[0031] Specifically, the support mechanism 2 is fixedly connected to the inner wall of the refrigerator body 11, including a fixed plate 21 fixedly connected to the inner wall of the refrigerator body 11. There are two fixed plates 21, which are symmetrically distributed and fixed inside the refrigerator body 11. Limiting components 22 are installed on the fixed plates 21. A docking groove 23 is opened on one side of the fixed plate 21. Multiple docking grooves 23 and limiting components 22 are opened on the fixed plate 21. The placement plate 31 on the storage mechanism 3 is inserted into it through the docking groove 23 to play a supporting and limiting role. The limiting component 22 limits and fixes the placement plate 31 inserted into the fixed plate 21 so that it will not move without human intervention. When the placement is tilted or vibrated, the placement plate 31 will slide off the fixed plate 21.

[0032] Specifically, the storage mechanism 3 is installed on the fixed plate 21 and includes a placement plate 31 that is inserted into the docking groove 23. The placement plate 31 is provided with an inclined surface to facilitate smoother insertion into the docking groove 23 and to smoothly press the locking block 22-2 on the limiting member 22 to move. The top of the placement plate 31 is provided with a placement groove 32, and an airbag 33 is fixedly connected in the placement groove 32. There are several placement grooves 32, and the number of airbags 33 corresponds to the number of grooves. When the airbags 33 are in their normal state, they can initially limit the storage dish in the placement groove 32 and play a buffering and protective role through elastic contact. When the placement plate 31 is gradually moved into the fixed plate 21.

[0033] An inflation component 34 is installed on the placement plate 31 and the airbag 33. An unlocking component 35 and a driving component 36 are respectively installed on the placement plate 31. The inflation component 34 is activated by the push rod 12, causing the airbag 33 to inflate and expand, making close contact with the surface of the storage dish, thus providing secondary reinforcement. At the same time, it seals the gap between the lid and the dish body, preventing gas from entering the storage dish and forming a physical sealing barrier to block gas exchange. It also prevents icing at the connection point, ensuring that the container can be opened effectively when taking it out.

[0034] The airbag 33 and the long groove 34-2 are filled with gas. This gas will not be greatly compressed in a low-temperature environment, but will only be slightly compressed, which will not affect the function of the airbag 33 on the storage dish. This is prior art, and those skilled in the art can clearly understand that the limiting member 22 can be released from the limiting of the placement plate 31 by the unlocking member 35 under the drive of the driving member 36, and the placement plate 31 can be pulled out from the docking groove 23 on the fixed plate 21.

[0035] Example 2 Reference Figures 2-7 This is the second embodiment of the present invention, which is based on the previous embodiment.

[0036] Specifically, the limiting member 22 includes a groove 22-1 formed in the fixed plate 21, and a locking block 22-2 is slidably connected in the groove 22-1. One end of the locking block 22-2 is provided with an inclined surface. With this setting, when the placement plate 31 is inserted into the docking groove 23 and the locking block 22-2 is moved and pressed, the locking block 22-2 can be moved into the groove 22-1, so that the placement plate 31 can be smoothly inserted into the docking groove 23.

[0037] A first spring 22-3 is fixedly connected between the surface of the locking block 22-2 and the inner wall of the groove 22-1. When the locking block 22-2 moves into the groove 22-1, the first spring 22-3 compresses and generates elastic force. When the placement plate 31 is fully inserted into the fixing plate 21, the locking block 22-2 corresponds to the slot 35-1. Under the action of the first spring 22-3, the locking block 22-2 is reset and inserted into the slot 35-1, thus limiting and fixing the placement plate 31 onto the fixing plate 21.

[0038] The inner wall of the groove 22-1 is provided with a first guide groove 22-4. The first guide block 22-5 is fixedly connected to the locking block 22-2 and is slidably connected in the first guide groove 22-4. The first guide groove 22-4 and the first guide block 22-5 guide and limit the locking block 22-2 to prevent it from detaching from the groove 22-1 on the fixing plate 21 under the action of the rebound of the first spring 22-3.

[0039] A rubber pad 22-6 is fixedly connected to one end of the locking block 22-2. The setting of the rubber pad 22-6 increases the resistance when the placement plate 31 moves and contacts the locking block 22-2. After the placement plate 31 is unlocked, it prevents the release of gas after compression and the effect of the airbag 33 returning to push the placement plate 31 a long distance out of the fixed plate 21.

[0040] The inflation component 34 includes a short tube 34-1 communicating with the surface of the airbag 33. There are several short tubes 34-1, which connect multiple airbags 33 on a placement plate 31. The placement plate 31 has a long groove 34-2, and a piston 34-3 is slidably connected in the long groove 34-2. One end of the short tube 34-1 communicates with the airbag 33, and one end of the push rod 12 is inserted into the long groove 34-2 and contacts the surface of the piston 34-3. With the setting of the piston 34-3, after the placement plate 31 is inserted into the docking groove 23, as the push rod 12 is inserted into the long groove 34-2 and contacts the piston 34-3, it can push the piston 34-3 to move in the long groove 34-2, so that the gas in the long groove 34-2 is filled into the airbag 33 and expands, thus fixing and sealing the storage container.

[0041] A sealing ring 34-4 is fitted on the surface of the piston 34-3, and its surface contacts the inner wall of the long groove 34-2. The sealing ring 34-4 seals the piston 34-3 and the inner wall of the long groove 34-2 to prevent gas leakage. The bottom of the placement plate 31 has a threaded hole that communicates with the long groove 34-2. A plug is threaded into the threaded hole, which allows for easy replenishment of air into the airbag 33 and the long groove 34-2 after prolonged use to ensure normal operation.

[0042] The unlocking component 35 includes a slot 35-1 formed in the placement plate 31. After the card block 22-2 is inserted into the slot 35-1, it limits the movement between the placement plate 31 and the fixing plate 21. The unlocking plate 35-2 is slidably connected in the slot 35-1. The movement of the unlocking plate 35-2 pushes the card block 22-2 to move, causing the card block 22-2 to disengage from the slot 35-1, thereby releasing the limiting component 22 from limiting and fixing the placement plate 31.

[0043] A second guide groove 35-3 is provided on the inner wall of the slot 35-1. A second guide block 35-4 is fixedly connected to the unlocking component 35 and is slidably connected in the second guide groove 35-3. The second guide groove 35-3 and the second guide block 35-4 limit and guide the unlocking plate 35-2, allowing it to move within a certain range. A second spring 35-5 is fixedly connected between the surface of the second guide block 35-4 and the inner wall of the second guide groove 35-3. One end of the locking block 22-2 is inserted into the slot 35-1. After the unlocking plate 35-2 moves and drives the second guide block 35-4 to move, the second spring 35-5 is stretched to generate elastic force, providing a force for the reset of the second guide block 35-4 and the unlocking plate 35-2.

[0044] The driving component 36 includes a rotating cylinder 36-1 rotatably connected to the placement plate 31. The rotating cylinder 36-1 is rotatably connected to the placement plate 31 via a bearing. A cam 36-2 is fixedly connected to one end of the rotating cylinder 36-1 located in the slot 35-1. As the cam 36-2 rotates with the rotating cylinder 36-1, it contacts and presses against the unlocking plate 35-2, causing the unlocking plate 35-2 to move. This, in turn, pushes the locking block 22-2 to move and disengage from the slot 35-1 on the placement plate 31. A groove 36-3 is provided inside the rotating cylinder 36-1, and a short rod 36-4 is slidably connected to the rotating cylinder 36-1.

[0045] One end of the short rod 36-4 is fixedly connected to a round block 36-5, and a limiting post 36-6 is fixedly connected to the round block 36-5. A limiting groove 36-7 that cooperates with the limiting post 36-6 is opened in the groove 36-3. With the setting of the limiting post 36-6 and the limiting groove 36-7, when the limiting post 36-6 is not in the limiting groove 36-7, rotating the short rod 36-4 will not cause the rotating drum 36-1 and the cam 36-2 to rotate, which plays a role in preventing accidental unlocking. When the limiting post 36-6 is in the limiting groove 36-7, rotating the short rod 36-4 will cause the rotating drum 36-1 and the cam 36-2 to rotate.

[0046] A handle 36-8 is fixedly connected to one end of the short rod 36-4. Rotating the handle 36-8 facilitates the rotation of the short rod 36-4, making operation easier. A third spring 36-9 is sleeved on the surface of the short rod 36-4, and its two ends are in contact with the inner wall of the groove 36-3 and the surface of the round block 36-5, respectively. Due to the setting of the third spring 36-9, when the handle 36-8 is pulled to move the short rod 36-4, the round block 36-5 and the limiting post 36-6, the limiting post 36-6 moves into the limiting groove 36-7 and is compressed. When the handle 36-8 is released, the short rod 36-4, the round block 36-5, the limiting post 36-6 and the handle 36-8 return to their original positions under the action of its elasticity.

[0047] The side of the placement plate 31 is provided with a buffer groove 37. When the placement plate 31 moves from the fixed plate 21, the locking block 22-2 and the rubber pad 22-6 on it move within it, which plays a buffering role and reduces the mechanical impact during storage and retrieval. The top of the placement plate 31 is provided with a through hole 38, which allows the gas flow inside the refrigerator body 11 to be normal and makes the temperature distribution more uniform.

[0048] When in use, hold the handle 36-8 and apply force outward and rotate it, so that the limiting post 36-6 moves and drives the limiting groove 36-7 into the groove. This causes the handle 36-8 to rotate, which in turn drives the rotating cylinder 36-1 and the cam 36-2 to rotate and contact and press with the unlocking plate 35-2, causing the unlocking plate 35-2 to move and thus push the locking block 22-2 to move away from the slot 35-1 on the placement plate 31.

[0049] Then, the placement plate 31 is moved to place the storage dish into the placement slot 32 and into the air bladder 33. The placement plate 31 is pushed into the refrigerator body 11. After the placement plate 31 is inserted into the docking slot 23, the moving push rod 12 is inserted into the long slot 34-2 and contacts the piston 34-3. This pushes the piston 34-3 to move within the long slot 34-2, causing the gas in the long slot 34-2 to fill the air bladder 33 and expand, thus fixing and sealing the storage dish and providing secondary reinforcement. At the same time, it seals the gap between the lid and the dish body to prevent gas from entering the storage dish and also prevents icing at the connection point, ensuring that the dish can be opened effectively when removed.

[0050] In summary, with the cooperation of the support mechanism 2 and the push rod 12, the storage mechanism 3 can prevent the sample container from shifting, colliding, or even breaking when the equipment is moved or vibrated. Furthermore, the seal between the lid of the storage dish and the container is not prone to cold air seeping in, and it is not easy to freeze and stick together, making it easy to open during resuscitation.

[0051] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the spirit and scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. A biological sample storage device for storing stem cells, characterized in that: include, The refrigeration mechanism (1) includes a refrigerator body (11), and a push rod (12) is fixedly connected to the inner wall of the refrigerator body (11). The support mechanism (2) is fixedly connected to the inner wall of the refrigerator body (11), including a fixing plate (21) fixedly connected to the inner wall of the refrigerator body (11), a limiting member (22) is installed on the fixing plate (21), and a docking groove (23) is provided on one side of the fixing plate (21); and, The storage mechanism (3) is installed on the fixed plate (21) and includes a placement plate (31) inserted into the docking slot (23). The top of the placement plate (31) is provided with a placement slot (32). An airbag (33) is fixedly connected in the placement slot (32). An inflation component (34) is installed on the placement plate (31) and the airbag (33). An unlocking component (35) and a driving component (36) are respectively installed on the placement plate (31).

2. The biological sample storage device for storing stem cells as described in claim 1, characterized in that: The limiting member (22) includes a groove (22-1) opened in the fixed plate (21), a locking block (22-2) is slidably connected in the groove (22-1), and a first spring (22-3) is fixedly connected between the surface of the locking block (22-2) and the inner wall of the groove (22-1).

3. The biological sample storage device for storing stem cells as described in claim 2, characterized in that: The inner wall of the groove (22-1) is provided with a first guide groove (22-4), and the first guide block (22-5) is fixedly connected to the card block (22-2) and is slidably connected in the first guide groove (22-4).

4. The biological sample storage device for storing stem cells as described in claim 3, characterized in that: A rubber pad (22-6) is fixedly connected to one end of the card block (22-2).

5. The biological sample storage device for storing stem cells as described in claim 1, characterized in that: The inflatable component (34) includes a short tube (34-1) connected to the surface of the airbag (33), a long groove (34-2) is provided in the placement plate (31), a piston (34-3) is slidably connected in the long groove (34-2), one end of the short tube (34-1) is connected to the airbag (33), and one end of the push rod (12) is inserted into the long groove (34-2) and contacts the surface of the piston (34-3).

6. The biological sample storage device for storing stem cells as described in claim 5, characterized in that: The piston (34-3) is fitted with a sealing ring (34-4), and its surface is in contact with the inner wall of the long groove (34-2).

7. The biological sample storage device for storing stem cells as described in claim 2, characterized in that: The unlocking component (35) includes a slot (35-1) opened in the placement plate (31), an unlocking plate (35-2) is slidably connected in the slot (35-1), a second guide groove (35-3) is opened in the inner wall of the slot (35-1), a second guide block (35-4) is fixedly connected to the unlocking component (35) and is slidably connected in the second guide groove (35-3), a second spring (35-5) is fixedly connected between the surface of the second guide block (35-4) and the inner wall of the second guide groove (35-3), and one end of the locking block (22-2) is inserted into the slot (35-1).

8. The biological sample storage device for storing stem cells as described in claim 7, characterized in that: The driving component (36) includes a rotating cylinder (36-1) rotatably connected to the placement plate (31). A cam (36-2) is fixedly connected to one end of the rotating cylinder (36-1) located in the slot (35-1). A groove (36-3) is opened in the rotating cylinder (36-1). A short rod (36-4) is slidably connected to the rotating cylinder (36-1). A round block (36-5) is fixedly connected to one end of the short rod (36-4). A limit post (36-6) is fixedly connected to the round block (36-5). A limit groove (36-7) that cooperates with the limit post (36-6) is opened in the groove (36-3).

9. The biological sample storage device for storing stem cells as described in claim 8, characterized in that: One end of the short rod (36-4) is fixedly connected to a handle (36-8), and a third spring (36-9) is sleeved on the surface of the short rod (36-4), with its two ends respectively contacting the inner wall of the groove (36-3) and the surface of the round block (36-5).

10. The biological sample storage device for storing stem cells as described in claim 1, characterized in that: The placement plate (31) has a buffer groove (37) on its side and a through hole (38) on its top.

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