Automatic sample adding device for preparing drug sensitive bacteria suspension with saline

Abstract

The utility model relates to brine sampling device field especially relates to automatic brine sampling device for drug sensitive bacteria suspension preparation, including mesa, mesa lower extreme is equipped with the support component of adjustable height, is equipped with the through groove of containing charging battery in support component, and is equipped with battery electric quantity display screen and external power supply socket for battery state monitoring and external charging, is equipped with mounting groove on mesa, the mounting groove bottom is opened through -hole, sampler host computer is detachably installed in mounting groove, and sampler host computer is constituted by upper part body and lower part body, and the built -in control mainboard and battery of upper part body, and the outside integration has body display screen, control button and body charging connector for operation interface and power management, and the lower part body includes stand, and the water pipe is set up in stand, the utility model discloses through automatic sampling and realizes bacteria suspension efficient configuration, reduces manual operation, avoids cross -contamination, promotes efficiency, and detachable protection component and clamping guide linkage enhance operation flexibility and convenience.

Description

Technical Field

[0001] This utility model relates to the field of saline sample dispensing devices, and more particularly to an automatic saline sample dispensing device for preparing drug-sensitive bacterial suspensions. Background Technology

[0002] In microbiology laboratories, the preparation of drug-sensitive bacterial suspensions is a fundamental step in drug susceptibility testing. The procedure must be strictly followed according to standardized protocols. First, typical colonies are picked from pure cultures and diluted with sterile physiological saline or buffer to a 0.5 McFarland turbidity standard (approximately 1 × 10⁻⁶). 8 (CFU / mL), and the concentration should be calibrated by spectrophotometer if necessary. The suspension should be prepared and used immediately to avoid changes in bacterial count due to storage. At the same time, attention should be paid to the activity, uniformity and absence of contamination of the strain to ensure that the results of subsequent antimicrobial susceptibility paper diffusion method or microbroth dilution method can be reproduced.

[0003] However, traditional saline pipettes cannot accommodate saline bottles of different sizes, requiring the replacement of saline bottles or the addition of other plugs, which increases a lot of tedious work. Furthermore, operators need to manually adjust the scale and add the sample, making it difficult to guarantee the accuracy of the sample addition, which in turn affects the accuracy and reliability of drug sensitivity testing. Utility Model Content

[0004] To overcome the problems of traditional saline pipettes, such as high workload due to manual operation, accuracy affected by individual differences, increased risk of bacterial suspension contamination, and impact on the accuracy of drug sensitivity testing.

[0005] The technical solution of this utility model is as follows: an automatic saline sampler for preparing drug-sensitive bacterial suspension, comprising a platform, an adjustable-height support assembly installed at the lower end of the platform, a through slot for accommodating a rechargeable battery within the support assembly, and equipped with a battery power display screen and an external power socket for battery status monitoring and external charging. The platform has a mounting slot with a through hole at the bottom. The sampler main unit is detachably installed in the mounting slot. The sampler main unit consists of an upper body and a lower body. The upper body houses the control motherboard and a battery, and the external power supply... The device includes a display screen, control buttons, and a charging connector for operation and power management. The lower part of the device includes a column with a water pipe inside. The end of the water pipe has a saline connector that matches the through hole. A water outlet is fixed to the outer wall of the water pipe, and a protective component is detachably connected to the end of the water outlet. The table also has a clamping unit for fixing the main unit of the sampler and a guide component that is linked to the clamping unit. A boss is fixed on the table, and a charging connection point is arranged on the boss. The charging connection point is connected to the charging connector of the device to supply power to the main unit of the sampler.

[0006] Preferably, the support assembly includes a fixed post fixed to the lower end of the tabletop, the fixed post having a threaded screw rod connected to it, and the lower end of the screw rod having an integrally formed support leg.

[0007] Preferably, the screw has a locking ring threaded on its outer wall, and the outer wall of the locking ring is provided with anti-slip texture.

[0008] Preferably, the protective component includes a protective tube with external threads on its outer wall and internal threads on the inner wall of the water outlet. The protective tube is threadedly connected to the water outlet, and a filter membrane is installed inside the protective tube.

[0009] Preferably, the clamping unit includes a support plate fixedly connected to the table surface, a bidirectional lead screw is provided inside the support plate, a knob is provided at the end of the bidirectional lead screw, a movable seat is threadedly connected to the outer wall of the bidirectional lead screw, and a clamping plate is fixedly connected to the upper end of the movable seat.

[0010] Preferably, the guide assembly includes a groove formed on the table surface, a slide rail is provided in the groove, a slider is slidably connected on the slide rail, and the end face of the slider is fixedly connected to the end face of the movable seat.

[0011] Preferably, the end of the saline connector is provided with a spiral interface, which can be adapted to the diameter of the saline bottle.

[0012] The beneficial effects of this utility model are:

[0013] 1. By setting up an adjustment device consisting of a fixed column and a locking ring, and a fixing structure consisting of a clamp and a column, which work together, it can adapt to saline bottles of different heights, thereby avoiding the cumbersome bottle changing procedure, reducing the use of plug-in components, and reducing the risk of cross-contamination.

[0014] 2. By automatically adding samples, efficient preparation of bacterial suspensions is achieved, reducing the need for manual operation, further avoiding the risk of cross-contamination of bacterial suspensions during the preparation process, and improving preparation efficiency. Attached Figure Description

[0015] Figure 1 A schematic diagram of one embodiment of the automatic saline sample dispensing device for preparing drug-sensitive bacterial suspension according to this utility model;

[0016] Figure 2 What is shown is Figure 1 A schematic diagram of the charging connector in the mid-body area;

[0017] Figure 3 The diagram shown is a front view of this utility model;

[0018] Figure 4 What is shown is Figure 1 A schematic diagram of the structure of the central support component;

[0019] Figure 5 What is shown is Figure 1 A schematic diagram of the middle clamping unit.

[0020] Explanation of reference numerals in the attached diagram: 1. Tabletop; 2. Rechargeable battery; 3. Through slot; 4. Battery power display; 5. External power socket; 6. Mounting slot; 7. Body display; 8. Control buttons; 9. Body charging connector; 10. Column; 11. Saltwater connector; 12. Water outlet; 13. Boss; 14. Charging connection point; 15. Fixing column; 16. Screw; 17. Support leg; 18. Locking ring; 19. Protective tube; 21. Support plate; 22. Two-way lead screw; 23. Knob; 24. Moving base; 25. Clamping plate; 26. Groove; 27. Slide rail; 28. Slider. Detailed Implementation

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] Please see Figure 1 - Figure 5This utility model provides an embodiment of an automatic saline sampler for preparing drug-sensitive bacterial suspensions. The device includes a platform 1 with an adjustable-height support assembly installed at its lower end. The support assembly contains a slot 3 for accommodating a rechargeable battery 2 and is equipped with a battery power display screen 4 and an external power socket 5 for battery status monitoring and external charging. The platform 1 has a mounting slot 6 with a through hole at its bottom. The sampler main unit is detachably installed in the mounting slot 6. The sampler main unit consists of an upper body and a lower body. The upper body houses the control motherboard and battery, and externally integrates a body display screen 7, control buttons 8, and a body charging connector 9 for operation and power management. The lower body includes a column 10 with a water pipe inside. The end of the water pipe has a... A saline connector 11 adapted to the through-hole is provided, and a water outlet 12 is fixed to the outer wall of the water pipe. The end of the water outlet 12 is detachably connected to a protective component. The platform 1 is also equipped with a clamping unit for fixing the main unit of the sampler and a guide component linked to the clamping unit. A boss 13 is fixed on the platform 1, and a charging connection point 14 is arranged on the boss 13. The charging connection point 14 is connected to the main unit of the sampler through the charging connector 9 on the machine body to supply power. The platform 1 serves as the basic support platform for the entire automatic saline sampler for preparing drug-sensitive bacterial suspension. The support component has an adjustable height function. By adjusting the height of the support component, it can accommodate saline bottles of different sizes. The support component has a through slot 3 for accommodating the rechargeable battery 2. The rechargeable battery 2 provides mobile power support for the device. This design makes the device more portable. It can operate normally even without an external power supply, increasing the flexibility of the device. It is equipped with a battery power display screen 4, which shows the remaining power of the rechargeable battery 2 in real time, allowing operators to easily monitor the battery status. An external power socket 5 is used to charge the rechargeable battery 2 when an external power supply is available, ensuring the battery always has sufficient power. The saline connector 11 is threaded to an external saline bottle, allowing saline to flow smoothly from the bottle into the water pipe inside the pipette, providing a water source for saline addition during the preparation of drug-sensitive bacterial suspensions. The control motherboard, built into the upper part of the device, is the control component of the pipette. It integrates a microprocessor, memory, input / output interfaces, and other electronic components. The control motherboard receives commands from the operator via control... The system inputs operation commands via button 8 and precisely controls various components of the pipette main unit according to a preset program, such as controlling parameters like water flow rate, water dispensing time, and water dispensing speed, to achieve automatic saline sample dispensing. The built-in battery in the upper part of the unit serves as a backup power source, providing continuous power support when the external power supply is interrupted or malfunctions, ensuring uninterrupted sample dispensing. The display screen 7 provides an intuitive interface, showing various operating parameters, status, and battery level information, allowing operators to monitor the device's operation in real time. Control buttons 8 are used by the operator to input various operation commands to the control board, such as starting and stopping the sample dispensing operation.Adjusting sample loading parameters, etc., the charging connector 9 on the main body is used to charge the battery inside the upper body, ensuring that the battery always has sufficient power. The charging logic for the main unit of the sampler can be as follows: when no external power is connected, the built-in rechargeable battery 2 supplies power to the main unit of the sampler; when an external power is connected, the built-in rechargeable battery 2 is charged first (at this time, the built-in rechargeable battery 2 still supplies power to the main unit of the sampler); when the built-in rechargeable battery 2 is fully charged, the power supply switches to the external power supply to the main unit of the sampler. The column 10 provides installation space and support structure for the water pipe, allowing the water pipe to be stably fixed inside the main unit of the sampler. The water pipe is the channel for saline delivery, with one end connected to the saline connector 11 and the other end connected to the outlet water. The head 12 delivers saline solution from the saline bottle to the outlet head 12, enabling saline sample addition. The protective component protects the outlet head 12 from external contamination, impact, or damage. Its detachable design facilitates installation, removal, and cleaning. The clamping unit secures the main unit of the sampler, preventing it from shaking during operation. The guide component, linked to the clamping unit, provides guidance for the installation and removal of the main unit. A charging connection point 14 is located on the boss 13 and connects to the charging connector 9 on the machine body, supplying power to the main unit. When the main unit is installed in the mounting slot 6 of the platform 1, the charging connector 9 contacts the charging connection point 14, establishing a charging circuit.

[0023] Please see Figure 1 - Figure 3In this embodiment, the support assembly includes a fixed post 15 fixed to the lower end of the platform 1. A screw 16 is internally threaded onto the fixed post 15. A support foot 17 is integrally formed at the lower end of the screw 16. A locking ring 18 is threaded onto the outer wall of the screw 16. The outer wall of the locking ring 18 is provided with anti-slip texture. The protective assembly includes a protective tube 19. The outer wall of the protective tube 19 has external threads, and the inner wall of the water outlet 12 has internal threads. The protective tube 19 is threaded to the water outlet 12. A filter membrane is provided inside the protective tube 19. The fixed post 15 provides a stable installation base for the screw 16. The height of the support assembly can be adjusted by rotating the screw 16. When the screw 16 is rotated, it moves up and down within the fixed post 15, thereby changing the height of the platform 1 from the ground. After the screw 16 is adjusted to a suitable position, the locking ring 18 is rotated to tighten it with the fixed post 15. The screw 16 is locked in place by the friction between the locking ring 18 and the fixing post 15, preventing it from rotating unexpectedly due to device vibration or external force during use, thus ensuring the stability of the support assembly. The protective tube 19 is connected to the inner wall of the outlet head 12 by an internal thread, enabling a detachable connection between the protective tube 19 and the outlet head 12. This detachable design facilitates the installation, disassembly, cleaning, and replacement of the protective tube 19, improving the practicality and hygiene of the device. The filter membrane is installed inside the protective tube 19 and can filter the brine flowing out of the outlet head 12. During the brine transportation process, some impurities and particulate matter may be present. If these impurities enter the drug-sensitive bacterial suspension, they will affect the accuracy of the experimental results. The filter membrane can effectively intercept these impurities, ensuring that the brine added to the bacterial suspension is pure and free of impurities.

[0024] Please see Figure 2 , Figure 3 and Figure 5In this embodiment, the clamping unit includes a support plate 21 fixedly connected to the table 1. A bidirectional lead screw 22 is provided within the support plate 21, and a knob 23 is provided at the end of the bidirectional lead screw 22. A movable seat 24 is threadedly connected to the outer wall of the bidirectional lead screw 22, and a clamping plate 25 is fixedly connected to the upper end of the movable seat 24. The guide assembly includes a groove 26 formed on the table 1, a slide rail 27 is provided within the groove 26, and a slider 28 is slidably connected to the slide rail 27. The end face of the slider 28 is fixedly connected to the end face of the movable seat 24. The end of the saline connector 11 is provided with a spiral interface, which can be adapted to the diameter of the saline bottle. The support plate 21 provides an installation platform for the bidirectional lead screw 22. By rotating the knob 23, the bidirectional lead screw 22 is rotated. The special thread design of the bidirectional lead screw 22 allows the two movable seats 24 threadedly connected to its outer wall to move simultaneously in opposite directions. When the bidirectional lead screw 22 is rotated, the two movable seats 24 move closer to or further away from each other, thereby moving the clamping plate 25 and realizing the movement of the sample dispenser. During the clamping or releasing operation of the main unit, the surface of the clamping plate 25 is specially treated, such as by adding rubber pads, to increase the friction between it and the main unit of the sampler, preventing the main unit of the sampler from sliding or shaking during clamping. At the same time, the rubber pads also act as a buffer to prevent the clamping plate 25 from damaging the main unit of the sampler. The slide rail 27 is set in the groove 26, providing a sliding track for the slider 28. The slider 28 connects the moving seat 24 to the slide rail 27, allowing the moving seat 24 to slide on the slide rail 27 via the slider 28. The sliding of the slider 28 on the slide rail 27 provides precise guidance for the movement of the moving seat 24, ensuring the smoothness of the movement of the moving seat 24. Through the screw interface, the saline connector 11 can be tightly connected to saline bottles of different specifications, ensuring that the saline can be smoothly delivered from the saline bottle to the water pipe inside the main unit of the sampler. The design of the screw interface has good sealing performance, which can prevent the saline from leaking at the connection point and ensure the stability and safety of the saline delivery.

[0025] Working principle: First, adjust the height of the support assembly by rotating screw 16 according to the size of the saline bottle, so that the platform 1 and the saline bottle are at a suitable distance. Then, rotate locking ring 18 to lock screw 16 in the current position, ensuring the height of the support assembly is stable. Next, install the pipette main unit into the mounting slot 6 of the platform 1. At this time, the charging connector 9 of the machine body contacts the charging connection point 14, establishing a charging circuit to power the pipette main unit. If an external power supply is available, the built-in rechargeable battery 2 will be charged first, and the rechargeable battery 2 will power the pipette main unit. If the external power supply is unavailable, the rechargeable battery 2 will independently power the pipette main unit.

[0026] Subsequently, by rotating the knob 23, the bidirectional lead screw 22 is driven to rotate, causing the two moving seats 24 to move in opposite directions simultaneously, driving the clamping plate 25 to clamp the sample dispenser main unit, ensuring that it will not shake during operation. At the same time, the cooperation of the slide rail 27 and the slider 28 provides precise guidance for the movement of the moving seat 24, ensuring the stability of the clamping operation.

[0027] Next, connect the saline connector 11 to the external saline bottle via thread to ensure that the saline can smoothly enter the water pipe inside the sampler host from the saline bottle. At this time, the filter membrane inside the protective tube 19 will filter the saline to remove impurities and particles, ensuring the purity of the saline.

[0028] Then, the operator inputs operation commands through the machine's display screen 7 and control buttons 8, such as setting sample addition parameters (including water flow rate, water output time, water output speed, etc.). After receiving the commands, the control motherboard precisely controls each component of the sampler host according to the preset program to realize the automatic sample addition operation of saline.

[0029] Finally, after the sample addition operation is completed, loosen the clamp 25 by rotating the knob 23 in the opposite direction and remove the sampler main unit from the mounting slot 6. If it is necessary to clean or replace the protective tube 19, simply rotate the protective tube 19 to remove it from the water outlet 12, clean or replace it, and then reinstall it.

[0030] Through the above steps, efficient preparation of bacterial suspension is achieved through automatic sample addition, reducing manual operation, avoiding cross-contamination, and improving efficiency. The detachable protective components and clamping guide linkage enhance the flexibility and convenience of operation, solving the problems of large workload, accuracy affected by individual differences, and increased risk of bacterial suspension contamination in traditional saline samplers, which affect the accuracy of drug sensitivity testing.

Claims

1. An automatic saline sampler for preparing drug-sensitive bacterial suspensions, characterized in that: The device includes a tabletop (1), with an adjustable support assembly installed at the lower end of the tabletop (1). The support assembly has a through slot (3) for accommodating a rechargeable battery (2) and is equipped with a battery power display screen (4) and an external power socket (5) for battery status monitoring and external charging. The tabletop (1) has a mounting slot (6) with a through hole at the bottom. The sampler main unit is detachably installed in the mounting slot (6). The sampler main unit consists of an upper body and a lower body. The upper body has a built-in control motherboard and a battery, and externally integrates a body display screen (7), control buttons (8), and a body charging connector (9). The lower body includes a column (10), a water pipe is installed inside the column (10), a saline connector (11) adapted to the through hole is provided at the end of the water pipe, a water outlet (12) is fixed on the outer wall of the water pipe, and a protective component is detachably connected to the end of the water outlet (12). The table (1) is also provided with a clamping unit for fixing the sampler host and a guide component linked with the clamping unit. A boss (13) is fixed on the table (1), and a charging connection point (14) is arranged on the boss (13). The charging connection point (14) is connected to the charging connector (9) of the machine body to supply power to the sampler host.

2. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 1, characterized in that: The support assembly includes a fixed post (15) fixed to the lower end of the table (1), and a screw (16) is threaded into the fixed post (15). The lower end of the screw (16) is integrally formed with a support foot (17).

3. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 2, characterized in that: The screw (16) has a locking ring (18) threaded on its outer wall, and the outer wall of the locking ring (18) is provided with anti-slip texture.

4. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 3, characterized in that: The protective assembly includes a protective tube (19), the outer wall of which is provided with external threads, and the inner wall of the water outlet (12) is provided with internal threads. The protective tube (19) is threadedly connected to the water outlet (12), and a filter membrane is provided inside the protective tube (19).

5. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 4, characterized in that: The clamping unit includes a support plate (21) fixedly connected to the table (1), a bidirectional lead screw (22) is provided in the support plate (21), a knob (23) is provided at the end of the bidirectional lead screw (22), a movable seat (24) is threadedly connected to the outer wall of the bidirectional lead screw (22), and a clamping plate (25) is fixedly connected to the upper end of the movable seat (24).

6. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 5, characterized in that: The guide assembly includes a groove (26) formed on the table (1), a slide rail (27) is provided in the groove (26), a slider (28) is slidably connected on the slide rail (27), and the end face of the slider (28) is fixedly connected to the end face of the movable seat (24).

7. The automatic saline sampler for preparing drug-sensitive bacterial suspension according to claim 6, characterized in that: The end of the saline connector (11) is provided with a spiral interface, which can be adapted to the size of the saline bottle opening.

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