An optical detection device for fluorescence detection

Abstract

The utility model discloses an optical detection device for fluorescent detection, including light emitting module and light receiving module, light emitting module includes the first light source unit, light receiving lens, first filter, light combiner and projection lens that arrange in proper order, the first light source unit includes one or more light sources, and light receiving lens converts light beam into the light beam of light ray included angle less than first preset value, and light combiner is used for deflection and converging the light after the light of first filter, and projection lens is used for projecting light on the object of being detected, makes the object of being detected and be excited to emit fluorescence, light receiving module includes the light receiving lens, light splitting unit, second filter, condenser lens and sensor that arrange in proper order, and light receiving lens is used for receiving fluorescence and converts it into the light beam of light ray included angle less than second preset value, and light splitting unit is used for and will different wavelength light ray guide to different direction, and the light ray of different direction enters sensor after the second filter and condenser lens of this direction in proper order. Improve the light receiving and transmitting efficiency.

Description

Technical Field

[0001] This utility model belongs to the field of optical detection device technology, and more specifically, it relates to an optical detection device for fluorescence detection. Background Technology

[0002] In detection instruments, such as biological instruments, the signal to be detected is generated in the form of fluorescence, where a small object exists within the target. Conventional fluorescence detection modules have low light-gathering efficiency when detecting small objects. Moreover, they are not suitable for multi-wavelength testing systems. Summary of the Invention

[0003] In view of the shortcomings of the existing technology, this utility model innovatively provides an optical detection device for fluorescence detection, which can focus light onto a small object, improve the light absorption and emission efficiency, and support multiple wavelengths.

[0004] To achieve the aforementioned technical objectives, this utility model discloses an optical detection device for fluorescence detection, comprising a light-emitting module and a light-receiving module. The light-emitting module includes a first light source unit, a light-collecting lens, a first filter, a light-combining lens, and a projection lens arranged in sequence. The first light source unit includes one or more light sources, which are arranged in rows or arrays, and emit light of different wavelengths. The light-receiving lens receives the light beam emitted by the light source and converts it into a light beam with an angle less than a first preset value, where the first preset value is 5° to 10°. The first filter is used to transmit light of a specific wavelength. The light-combining lens is used to deflect and converge the light that has passed through the first filter. The projection lens is used to project the light after passing through the combining lens onto the object being detected, so that the object being detected is excited to emit fluorescence. The light-receiving module includes a light-receiving lens, a beam-splitting unit, a second filter, a condensing lens, and a sensor arranged in sequence. The light-receiving lens is used to receive the fluorescence emitted by the object being detected and convert it into a light beam with an angle less than a second preset value, the second preset value being 5°~10°. The beam splitting unit is used to receive the light after it has been converted by the light-receiving lens and guide light of different wavelengths in different directions. The light of different directions passes through the second filter and the condenser lens in that direction in sequence before entering the sensor.

[0005] Furthermore, the light-emitting module also includes a first dichroic mirror, which is disposed between the first filter and the light-combining lens, and the first dichroic mirror forms an angle of 45° or 75° with the optical axis of the light source of the first light source unit.

[0006] Furthermore, the light-emitting module also includes a second light source unit, which includes one or more light sources arranged in a row or array. The multiple light sources emit light of different wavelengths. The second light source unit and the first light source unit are distributed on different sides of the first dichroic mirror. The first dichroic mirror and the optical axis of the light source of the second light source unit are at an angle of 45° or 75°. The light-collecting lens and the first filter are sequentially arranged between the second light source unit and the first dichroic mirror.

[0007] Furthermore, the beam splitting unit includes multiple dichroic mirrors arranged in two rows. The two rows of dichroic mirrors are arranged in a direction away from the object being detected. The row of dichroic mirrors closer to the object being detected includes one or more dichroic mirrors. The number of dichroic mirrors in the row away from the object being detected is greater than the number of dichroic mirrors in the row closer to the object being detected. Each dichroic mirror forms a 45° angle with the optical axis of the light incident on it. Adjacent dichroic mirrors are arranged parallel or perpendicular to each other.

[0008] Furthermore, a heat dissipation device is provided on the side of the light source away from the light-collecting lens.

[0009] Furthermore, the light-collecting lens is a spherical lens, a plano-convex lens, or a crescent-shaped lens.

[0010] Furthermore, the combining lens is a spherical lens, an aspherical lens, a Fresnel lens, a cylindrical lens, or a compound eye lens with angular torsion.

[0011] Furthermore, the projection lens is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens.

[0012] Furthermore, the light-receiving lens is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens; and / or, the light-condensing lens is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens.

[0013] Furthermore, the second filter includes at least one of a bandpass filter, a longpass filter, a shortpass filter, a notch filter, and colored glass, and the second filters used to filter light from different directions may be of the same or different types.

[0014] The beneficial effects of this utility model are as follows: The optical detection device for fluorescence detection of this invention can focus light onto a small object, thereby improving the light absorption and emission efficiency and supporting multiple wavelengths. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of an optical detection device for fluorescence detection according to the first embodiment of this utility model.

[0016] Figure 2 This is a schematic diagram of the structure of an optical detection device for fluorescence detection according to the second embodiment of this utility model.

[0017] Figure 3 This is a schematic diagram of the structure of an optical detection device for fluorescence detection according to the third embodiment of this utility model.

[0018] Figure 4 This is a schematic diagram of the overall structure of an optical detection device for fluorescence detection according to an embodiment of the present invention.

[0019] In the picture, 1. Light-emitting module; 11. First light source unit; 12. Light-receiving lens; 13. First filter; 14. Light-combining lens; 15. Projection lens; 16. First dichroic mirror; 17. Second light source unit; 18. First housing; 2. Light-receiving module; 21. Light-receiving lens; 22. Beam-splitting unit; 221. Dichroic mirror; 222. Third dichroic mirror; 223. Fourth dichroic mirror; 224. Fifth dichroic mirror; 225. Sixth dichroic mirror; 23. Second filter; 24. Condensing lens; 25. Sensor; 26. Second housing; 27. Physical channel; 3. Heat dissipation device; 4. Detected object material; 5. Card box. Detailed Implementation

[0020] The optical detection device for fluorescence detection provided by this utility model will be explained and described in detail below with reference to the accompanying drawings.

[0021] This embodiment specifically discloses an optical detection device for fluorescence detection (hereinafter referred to as the optical detection device), such as... Figure 1 As shown, it includes a light-emitting module 1 and a light-receiving module 2. The light-emitting module 1 is used to emit one or more different wavelengths of light and then focus them onto the object being detected 4 after filtering. The light-receiving module 2 is used to receive the fluorescence emitted by the object being detected 4 and separate the light of different wavelengths in different directions to detect the information of the object being detected 4.

[0022] like Figure 1As shown, the light-emitting module 1 includes a first light source unit 11, a light-collecting lens 12, a first filter 13, a light-combining lens 14, and a projection lens 15 arranged in sequence. The optical axes of the light-collecting lens 12, the first filter 13, the light-combining lens 14, and the projection lens 15 can coincide.

[0023] The first light source unit 11 includes one or more light sources, arranged in rows or arrays, emitting light of different wavelengths. Preferably, the first light source unit 11 includes multiple light sources. The light sources can be one or more of LED lamps, lasers, halogen lamps, and deuterium lamps, emitting excitation light.

[0024] The light-collecting lens 12 receives the light beam emitted by the light source and converts it into a light beam with an angle less than a first preset value, which is 5° to 10°. Preferably, the light-collecting lens 12 converts the light rays in the light beam into approximately parallel light rays, thereby converging the light rays and increasing the amount of light received by subsequent components. The light-collecting lens 12 can be made of glass or plastic, etc. Optionally, the light-collecting lens 12 can be a spherical lens, a plano-convex lens, or a crescent-shaped lens.

[0025] The first filter 13 is used to transmit light of a specific wavelength and filter the light that has been converted into approximately parallel light by the light-collecting lens 12, so that the light of the desired wavelength can pass through the first filter 13. Preferably, the first filter 13 can be a filter with an OD (Optical Density) of 6 or higher, or a filter with a lower OD value can be selected depending on the specific circumstances.

[0026] The light-combining lens 14 is used to deflect and converge the light after it has passed through the first filter 13, and to converge the light again. Optionally, the light-combining lens 14 is a spherical lens, an aspherical lens, a Fresnel lens, a cylindrical lens, or a compound eye lens with angular twist, preferably a Fresnel lens.

[0027] The projection lens 15 is used to project the light after passing through the light combining lens 14 onto the object being detected 4, so that the object being detected 4 is excited to emit fluorescence; optionally, the projection lens 15 is a spherical lens, an aspherical lens, a Fresnel lens or a cylindrical lens.

[0028] like Figure 1 As shown, the light-receiving module 2 includes a light-receiving lens 21, a beam-splitting unit 22, a second filter 23, a condenser lens 24, and a sensor 25 arranged in sequence. The light-receiving lens 21 receives the fluorescence emitted by the object being detected 4 and converts it into a beam with an angle less than a second preset value, which is 5°~10°, thus converging the light. Preferably, the light-receiving lens 21 converts the light into approximately parallel light, increasing the amount of subsequent light received, thereby improving the light-receiving efficiency and detection efficiency. Optionally, the light-receiving lens 21 is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens; the light-receiving lens 21 is preferably a Fresnel lens.

[0029] The beam-splitting unit 22 receives the light converted by the light-receiving lens 21 and directs light of different wavelengths in different directions. The light from different directions passes sequentially through the second filter 23 and the condenser lens 24 in that direction before entering the sensor 25. One or two wavelengths of light can exist in the same direction. The beam-splitting unit 22 directs light of different wavelengths in different directions, and after being filtered by the second filter 23 to obtain the desired wavelength, the light is focused by the condenser lens 24 onto the corresponding sensor 25. The sensor 25 converts the received optical signal into an electrical signal. In other words, a second filter 23, a condenser lens 24, and a sensor 25 are sequentially arranged in each direction. The inclusion of the light-receiving module 2 improves the efficiency and accuracy of the detection.

[0030] Optionally, sensor 25 can be a photodiode, avalanche photodiode (APD), optical IC, SiPM / SPAD detector, photomultiplier tube (PMT), image sensor, or spectrometer / spectral sensor.

[0031] Optionally, the condenser lens 24 can be a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens. The condenser lens 24 is preferably a Fresnel lens.

[0032] Optional, such as Figure 1 As shown, the beam splitting unit 22 includes multiple dichroic mirrors arranged in two rows. The two rows of dichroic mirrors are arranged in a direction away from the object being detected 4. The row of dichroic mirrors closer to the object being detected 4 includes one or more dichroic mirrors. The number of dichroic mirrors in the row away from the object being detected 4 is greater than the number of dichroic mirrors in the row closer to the object being detected 4. The dichroic mirror is at a 45° angle to the optical axis of the light incident on it. Adjacent dichroic mirrors are arranged parallel or perpendicularly.

[0033] The row of dichroic mirrors closest to the object being detected 4 is defined as the first row of dichroic mirrors, and the row of dichroic mirrors furthest from the object being detected 4 is defined as the second row of dichroic mirrors. Figure 1As shown, the first row of dichroic mirrors includes two dichroic mirrors, namely a second dichroic mirror 221 and a third dichroic mirror 222. The second dichroic mirror 221 faces the object being detected 4, and the third dichroic mirror 222 is located to the right of the second dichroic mirror 221. The second dichroic mirror 221 and the third dichroic mirror 222 are arranged in parallel. The second dichroic mirror 221 and the third dichroic mirror 222 work together to guide a portion of the light to the right side of the third dichroic mirror 222. To the right of the third dichroic mirror 222, a second filter 23, a condenser lens 24 and a sensor 25 are arranged in sequence. The second row of dichroic mirrors includes three dichroic mirrors, arranged from left to right as the fourth dichroic mirror 223, the fifth dichroic mirror 224, and the sixth dichroic mirror 225. The fifth dichroic mirror 224 is in the same column as the second dichroic mirror 221 and is perpendicular to each other. The fourth dichroic mirror 223 is in the same column as the third dichroic mirror 222 and is parallel to the third dichroic mirror 222. The sixth dichroic mirror 225 is parallel to the fifth dichroic mirror 224. Through the action of the second dichroic mirror 221, the third dichroic mirror 222, the fourth dichroic mirror 223, the fifth dichroic mirror 224, and the sixth dichroic mirror 225, light is directed in six directions. These six directions can correspond to six physical channels 27, some of which can allow light of two wavelengths to pass through.

[0034] Optionally, the second filter 23 includes at least one of a bandpass filter, a longpass filter, a shortpass filter, a notch filter, and colored glass. The second filters 23 used to filter light from different directions may be of the same or different types. For example, a bandpass filter may be used to filter light from one direction, while a longpass filter may be used to filter light from another direction, so that the light entering the sensor 25 from each direction reaches the required wavelength.

[0035] Preferably, the second filter 23 can be a filter with an OD value of 6 or higher, or a filter with a lower OD value can be selected depending on the specific circumstances.

[0036] In one alternative embodiment, such as Figure 2As shown, the light-emitting module 1 also includes a first dichroic mirror 16, which is disposed between the first filter 13 and the beam combining lens 14. The first dichroic mirror 16 forms a 45° or 75° angle with the optical axis of the light source of the first light source unit 11. The dichroic mirror separates light according to its wavelength, splitting a beam of light into two or more beams of different wavelengths. It reflects shorter wavelengths of light and transmits longer wavelengths of light. For example, its main optical parameters achieve high reflectivity in the 500-580nm band and high transmittance in the 605nm-750nm band. By reflecting light in the 500-580nm band and transmitting light in the 605nm-750nm band, it achieves light separation, thereby allowing light of a specific wavelength band to shine onto the object being detected 4, reducing unnecessary light interference. The light separated by the first dichroic mirror 16 enters the beam combining lens 14 for deflection and convergence.

[0037] In one alternative embodiment, such as Figure 3 As shown, the light-emitting module 1 also includes a second light source unit 17, which includes one or more light sources arranged in a row or array. These light sources emit light of different wavelengths. The second light source unit 17 and the first light source unit 11 are distributed on different sides of the first dichroic mirror 16. The first dichroic mirror 16 forms a 45° or 75° angle with the optical axis of the light source of the second light source unit 17. The optical axes of the first dichroic mirror 16, the first light source unit 11, and the second light source unit 17 all form a 45° or 75° angle. A light-collecting lens 12 and a first filter 13 are sequentially arranged between the second light source unit 17 and the first dichroic mirror 16. The light emitted by the second light source unit 17 is converted by the light-collecting lens 12, filtered by the first filter 13, and then directed towards the first dichroic mirror 16. The wavelength of the light emitted by the second light source unit 17 may be the same as or different from the wavelength of the light emitted by the first light source unit 11.

[0038] like Figure 4As shown, the light-emitting module 1 of this application is provided with a first housing 18. The light-receiving lens 12, the first filter 13 and the light-combining lens 14 of the light-emitting module 1 are fixed in the first housing 18. The first light source unit 11 and the second light source unit 12 can be embedded in the light inlet of the first housing 18. When the light-emitting module 1 also includes a first dichroic mirror 16, the first dichroic mirror 16 is also fixed in the first housing 18. The first housing 18 has a light outlet. The projection lens 15 is embedded in the light outlet or fixed in the first housing 18. The first housing 18 assembles the light-emitting module 1 together and provides support. The light-receiving module 2 is provided with a second housing 26. The second housing 26 has a light inlet. The light-receiving lens 21 can be embedded in the light inlet or fixed in the second housing 26. The beam-splitting unit 22, the second filter 23, the condensing lens 24 and the sensor 25 can be fixed inside the second housing 26. The second housing 26 has physical channels 27 that can be configured for each direction. For example, a cylindrical cavity can be used as the physical channel 27. Each physical channel 27 can accommodate one wavelength or two different wavelengths of light in that direction. The sensor 25 can be fixed to the end of the physical channel 27. The axial direction of the light outlet of the first housing 18 and the axial direction of the light inlet of the second housing 26 can be set at a certain angle so that all the light converged by the beam combining lens 14 can be irradiated onto the object 4 being detected, and all the fluorescence energy excited by the object 4 can enter through the light inlet of the second housing 26 and pass through the light receiving lens 21, thereby improving the light absorption and absorption efficiency. The first housing 18 and the second housing 26 can be fixedly connected. During detection, the object 4 being detected can be placed at a specific position between the first housing 18 and the second housing 26, which is simple to operate.

[0039] In one alternative embodiment, such as Figures 1-4 As shown, a heat dissipation device 3 is provided on the side of the light source away from the light-collecting lens 12 to cool the light source, so that it can work normally and maintain the stability of the excitation light.

[0040] When using the optical detection device for fluorescence detection of this application, the object to be detected 4 is first placed between the light-emitting module 1 and the light-receiving module 2. The object to be detected 4 can be in solid or liquid form and can be placed in a transparent card box 5. Then, the card box 5 is placed between the light-emitting module 1 and the light-receiving module 2. The light source is turned on, and the light source emits excitation light of various wavelengths. After the excitation light is converted into approximately parallel light by the light-receiving lens 12, it is filtered into light of the required wavelength by the first filter 13. Then, after being reflected or transmitted by the first dichroic mirror 16, it enters the light-combining lens 14 where it is deflected and focused. Finally, it is projected onto the object to be detected 4 by the projection lens 15. The light emitted by the light source is separated, deflected, and focused multiple times before being projected onto the object to be detected 4. The light spot projected onto the object to be detected 4 is small, which can realize the detection of small target objects. It has been verified that the light-emitting module 1 of this application can focus the light into a circular light spot and a line light spot of 1 mm, thereby improving the luminous efficiency.

[0041] The light emitted by the light-emitting module 1 is projected onto the object being detected 4, which is then excited to emit fluorescence. The fluorescence is first converted into approximately parallel light by the light-receiving lens 21, and then separated and guided to different directions by the second dichroic mirror 221, the third dichroic mirror 222, the fourth dichroic mirror 223, the fifth dichroic mirror 224 and the sixth dichroic mirror 225. The light in each direction is then filtered by the second filter 23 and converged onto the sensor 25 by the condenser lens 24, where it is converted into an electrical signal to detect the information of the object being detected 4.

[0042] The light-collecting module 2 converts, separates, guides, and converges fluorescence, improving light-collecting efficiency and allowing the sensor 25 to receive more light, thus improving detection efficiency.

[0043] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0044] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0045] In the description of this specification, the references to terms such as "this embodiment," "an embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in a suitable manner in any at least one embodiment or example. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0046] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0047] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions and simple improvements made on the substantive content of the present utility model should be included within the protection scope of the present utility model.

Claims

1. An optical detection device for fluorescence detection, characterized in that, It includes a light-emitting module (1) and a light-receiving module (2). The light-emitting module (1) includes a first light source unit (11), a light-collecting lens (12), a first filter (13), a light-combining lens (14), and a projection lens (15) arranged in sequence. The first light source unit (11) includes one or more light sources, which are arranged in rows or arrays, and emit light of different wavelengths. The light-receiving lens (12) receives the light beam emitted by the light source and converts it into a light beam with an angle less than a first preset value, where the first preset value is 5°~10°. The first filter (13) is used to transmit light of a specific wavelength. The light-combining lens (14) is used to deflect and converge the light that has passed through the first filter (13). The projection lens (15) is used to project the light after passing through the light combining lens (14) onto the object to be detected (4), so that the object to be detected (4) is excited to emit fluorescence; The light receiving module (2) includes a light receiving lens (21), a beam splitting unit (22), a second filter (23), a condenser lens (24), and a sensor (25) arranged in sequence. The light-receiving lens (21) is used to receive the fluorescence emitted by the object being detected (4) and convert it into a light beam with an angle less than a second preset value, the second preset value being 5°~10°. The beam splitting unit (22) is used to receive the light after it has been converted by the light receiving lens (21) and guide the light of different wavelengths in different directions. The light of different directions passes through the second filter (23) and the condenser lens (24) in that direction in sequence and then enters the sensor (25).

2. The optical detection device for fluorescence detection according to claim 1, characterized in that, The light-emitting module (1) further includes a first dichroic mirror (16), which is disposed between the first filter (13) and the light-combining lens (14). The first dichroic mirror (16) forms an angle of 45° or 75° with the optical axis of the light source of the first light source unit (11).

3. The optical detection device for fluorescence detection according to claim 2, characterized in that, The light-emitting module (1) further includes a second light source unit (17), which includes one or more light sources arranged in a row or array. The multiple light sources emit light of different wavelengths. The second light source unit (17) and the first light source unit (11) are distributed on different sides of the first dichroic mirror (16). The optical axis of the light source of the first dichroic mirror (16) and the light source of the second light source unit (17) are at an angle of 45° or 75°. The light-collecting lens (12) and the first filter (13) are arranged sequentially between the second light source unit (17) and the first dichroic mirror (16).

4. The optical detection device for fluorescence detection according to claim 1, characterized in that, The beam splitting unit (22) includes multiple dichroic mirrors arranged in two rows. The two rows of dichroic mirrors are arranged in a direction away from the object being detected (4). The row of dichroic mirrors closer to the object being detected (4) includes one or more dichroic mirrors. The number of dichroic mirrors in the row of dichroic mirrors farther from the object being detected (4) is greater than the number of dichroic mirrors in the row of dichroic mirrors closer to the object being detected (4). The dichroic mirrors are at a 45° angle to the optical axis of the light rays incident on the dichroic mirrors. Adjacent dichroic mirrors are arranged parallel or perpendicularly.

5. The optical detection device for fluorescence detection according to claim 1 or 3, characterized in that, A heat dissipation device (3) is provided on the side of the light source away from the light-collecting lens (12).

6. The optical detection device for fluorescence detection according to claim 1, characterized in that, The light-collecting lens (12) is a spherical lens, a plano-convex lens, or a crescent-shaped lens.

7. The optical detection device for fluorescence detection according to claim 1, characterized in that, The combining lens (14) is a spherical lens, an aspherical lens, a Fresnel lens, a cylindrical lens, or a compound eye lens with angular torsion.

8. The optical detection device for fluorescence detection according to claim 1, characterized in that, The projection lens (15) is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens.

9. The optical detection device for fluorescence detection according to claim 1, characterized in that, The light-receiving lens (21) is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens; and / or, the light-concentrating lens (24) is a spherical lens, an aspherical lens, a Fresnel lens, or a cylindrical lens.

10. The optical detection device for fluorescence detection according to claim 1, characterized in that, The second filter (23) includes at least one of a bandpass filter, a long pass filter, a short pass filter, a notch filter, and colored glass. The second filters (23) used to filter light from different directions may be of the same or different types.

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