High-cleanliness fluorescence interference resistant slide glass

By designing a groove depth decreasing structure and a low-fluorescence material on the glass slide, combined with mistake-proof markings and an anti-contamination coating, the problems of sample spillage and fluorescence interference are solved, resulting in a high-cleanliness anti-fluorescence interference glass slide, which improves the accuracy and signal-to-noise ratio of fluorescence detection.

CN224536272UActive Publication Date: 2026-07-21江苏世泰诊断技术有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
江苏世泰诊断技术有限公司
Filing Date
2025-10-27
Publication Date
2026-07-21

AI Technical Summary

Technical Problem

Existing partitioned slides suffer from sample spillage, cross-regional contamination, and fluorescence interference, affecting the accuracy and signal-to-noise ratio of fluorescence detection.

Method used

The design incorporates a groove depth that decreases from the edge to the center and a height difference of a > b. It utilizes low-fluorescence-background quartz glass or high-borosilicate glass and features an anti-contamination coating on the surface, along with foolproof markings to prevent sample spillage and cross-contamination, thereby reducing fluorescence interference.

Benefits of technology

This effectively avoids sample spillage and cross-regional contamination, reduces non-specific fluorescence signals, improves the signal-to-noise ratio of fluorescence detection, and ensures the authenticity and reliability of the detection results.

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Abstract

The utility model discloses a kind of high-cleanliness anti-fluorescence interference type glass slides, including glass slide main body, a plurality of uniformly distributed grooves are equipped on glass slide main body, coaxially be equipped with center boss in groove;Height difference a of groove edge and glass slide main body is greater than height difference b of center boss and glass slide main body, and groove depth is smoothly decreasing from edge to center. Through the composite structure design of "edge deep, center shallow+center boss", the problem that sample overflow, capillary action leads to sample cross-zone pollution when traditional glass slide is pressed is solved;Low fluorescence background material and anti-pollution coating are simultaneously used, to further reduce fluorescence detection interference. The glass slide can realize multiple sample synchronous detection, suitable for cell fluorescence staining, immunofluorescence analysis and other high-cleanliness and anti-interference requirement scene, with the advantages of simple structure, strong practicality, high detection accuracy.
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