A cleaning device for a WB loading comb

Abstract

The utility model discloses a kind of cleaning devices of WB sample comb, belong to biomedical experimental equipment cleaning technical field, the cleaning device of the WB sample comb includes cleaning tank, the top of the cleaning tank is provided with fixed cover, a sample comb cleaning slit for WB sample comb comb tooth is passed through and is arranged in the fixed cover, the inside of cleaning tank is provided with brush, the brush is below the sample comb cleaning slit.In the WB sample comb cleaning of being carried out, when sample comb is vertically inserted sample comb cleaning slit and repeatedly pulls, brush can be in-depth to each tooth of WB sample comb and tooth surface, and residual is thoroughly removed by friction effect, effectively avoid the problem that residual blocks sample hole, ensure subsequent glue quality, reduce experimental error, solve the problem that common WB sample comb cleaning mode cannot effectively clean gel residue adhered firmly in the interdental slit of sample comb tooth.

Description

Technical Field

[0001] This utility model relates to the field of cleaning technology for biomedical experimental equipment, specifically to a cleaning device for a WB sample comb. Background Technology

[0002] Western blotting (WB) is an indispensable technique in biomedical research, used to detect the expression levels of specific proteins. In WB experiments, preparing a polyacrylamide gel is a fundamental step, while the sample comb is the core tool for forming the sample wells on the gel.

[0003] Sample loading combs are typically made of plastic and have multiple evenly spaced teeth. During gel polymerization, the comb is inserted into the top of the unsolidified gel solution. After the gel solidifies, it is pulled out, creating a sample well on the gel surface for sample loading. After each use, unpolymerized acrylamide solution, gel fragments, or other experimental residues inevitably remain between the teeth and on the surface of the comb. If these residues are not removed promptly and thoroughly, they can clog the sample wells, affecting the quality of subsequent gel preparation and introducing experimental errors.

[0004] Currently, the common cleaning method is simply rinsing the comb teeth surface under running water. While simple, this method has limited effectiveness, being almost entirely ineffective at removing firmly adhered gel residues within the narrow gaps between the teeth, and thus failing to thoroughly clean them. Therefore, it is necessary to propose a cleaning device for WB sample combs to address these issues. Utility Model Content

[0005] Based on the problems existing in the above-mentioned background technology, this utility model proposes a cleaning device for WB sample loading combs, which solves the problem that common WB sample loading comb cleaning methods cannot effectively clean the firmly adhered gel residue in the narrow gaps between the sample loading comb teeth.

[0006] To achieve the above-mentioned objectives, the technical solution adopted by this utility model is as follows: This utility model provides a cleaning device for a WB sample comb, which includes a cleaning tank, a fixed cover on the top of the cleaning tank, a sample comb cleaning slit through which the comb teeth of the WB sample comb pass, and a brush inside the cleaning tank, the brush being located below the sample comb cleaning slit.

[0007] In practical use, a cleaning device for WB sample-applying combs involves first injecting cleaning fluid into a cleaning tank, then connecting a fixed cover to the cleaning tank to prevent the cleaning fluid from leaking out. Next, the user vertically inserts the WB sample-applying comb into the cleaning slot of the comb and into contact with the brush, and manually pulls the WB sample-applying comb repeatedly. The brush effectively cleans the surface of the WB sample-applying comb and the narrow gaps between the comb teeth, solving the problem that common cleaning methods cannot effectively clean the firmly adhered gel residue in the narrow gaps between the comb teeth.

[0008] Furthermore, the cleaning tank has a hollow cuboid structure, and the fixing cover has a rectangular plate structure. The fixing cover is detachably connected to the top opening of the cleaning tank.

[0009] Furthermore, the sample comb cleaning slit is arranged along the length direction of the fixed cover, the sample comb cleaning slit is located in the middle of the fixed cover, the brush is located directly below the sample comb cleaning slit, the brush is arranged along the length direction of the cleaning trough, and the length covered by the brush is greater than the length of the sample comb cleaning slit.

[0010] Furthermore, there are two brushes, which are symmetrically arranged on the two inner walls of the cleaning tank in the width direction. The cleaning bristles of the two brushes are horizontally arranged, and the distance between the ends of the cleaning bristles of the two brushes is 0.1mm.

[0011] Furthermore, the diameter of the cleaning bristles in each of the brushes is smaller than the tooth spacing of the WB sample comb.

[0012] Furthermore, the vertical distance between the brush and the sample comb cleaning slit is 1mm to 3mm.

[0013] Furthermore, a slot is provided at the top opening of the cleaning tank, and buckles are provided at the four edges of the fixing cover. The fixing cover and the cleaning tank can be detachably connected by the cooperation of the buckles and the slot.

[0014] Compared with the common WB sample comb cleaning method, the beneficial effects of this utility model are: 1. Traditional methods of simply rinsing the comb surface under running water are almost ineffective for removing firmly adhered gel residues, incompletely polymerized acrylamide solution, and other experimental residues from the narrow gaps between the teeth. This invention provides a cleaning device for a WB sample loading comb. During cleaning, the sample loading comb is vertically inserted into the cleaning slot and repeatedly pulled out. The brush can penetrate deep into each gap and surface of the WB sample loading comb, thoroughly removing residues through friction. This effectively avoids the problem of residue clogging the sample loading holes, ensuring the quality of subsequent gel preparation and reducing experimental errors.

[0015] 2. This utility model provides a cleaning device for WB sample combs. Users simply insert the sample comb vertically into the cleaning slot of the fixed cover and then manually pull it repeatedly to complete the cleaning process. No complicated operating procedures or professional skills are required. Compared with traditional manual brushing, this significantly saves operating time and effort and improves cleaning efficiency. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the embodiments will be briefly described below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. The above and other objects, features, and advantages of this utility model will become clearer through the drawings. The same reference numerals indicate the same parts in all the drawings. The drawings are not intentionally drawn to scale to actual dimensions; the focus is on illustrating the main idea of ​​this utility model.

[0017] Figure 1 This is a schematic diagram of the structure of a cleaning device for a WB sample comb proposed in this utility model.

[0018] The components include: 1. a cleaning tank; 2. a fixing cover; 3. a sample comb cleaning seam; and 4. a brush. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. The components of the embodiments of this utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0020] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0021] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0022] Please refer to Figure 1 As shown, this utility model provides a cleaning device for a WB sample comb, which includes a cleaning tank 1, a fixed cover 2 on the top of the cleaning tank 1, a sample comb cleaning slit 3 through which the comb teeth of the WB sample comb pass, and a brush 4 inside the cleaning tank 1, the brush 4 being located below the sample comb cleaning slit 3.

[0023] The cleaning tank 1 has a hollow cuboid structure, and the fixing cover 2 has a rectangular plate structure. The fixing cover 2 is detachably connected to the top opening of the cleaning tank 1. Specifically, the top opening of the cleaning tank 1 is provided with a slot, and the four edges of the fixing cover 2 are provided with buckles. The fixing cover 2 and the cleaning tank 1 are detachably connected by the cooperation of the buckles and the slots, which facilitates cleaning and maintenance of the cleaning tank 1 and the fixing cover 2 after use, and also facilitates the replacement of the brush 4.

[0024] The sample comb cleaning slit 3 is arranged along the length of the fixed cover 2, and is located in the middle of the fixed cover 2. The brush 4 is located directly below the sample comb cleaning slit 3, and is arranged along the length of the cleaning groove 1. The length covered by the brush 4 is greater than the length of the sample comb cleaning slit 3. The diameter of the cleaning bristles in the brush 4 is smaller than the spacing between the teeth of the WB sample comb, so that the cleaning bristles in the brush 4 can easily enter between the teeth of the WB sample comb.

[0025] The number of brushes 4 is two, and the two brushes 4 are symmetrically arranged on the two inner walls of the cleaning tank 1 in the width direction. The cleaning bristles of the two brushes 4 are horizontally arranged, and the distance between the ends of the cleaning bristles of the two brushes 4 is 0.1mm, so as to facilitate the insertion of the WB sample comb between the two brushes 4.

[0026] The vertical distance between the brush 4 and the sample comb cleaning slit 3 is 1mm to 3mm. When cleaning the WB sample comb, the brush 4 can clean the bottom between the WB sample comb teeth.

[0027] In the above technical solution, the brush 4 is a flexible brush. These brushes 4 can be made of materials such as nylon, which have good flexibility and abrasion resistance. During the cleaning process, they can effectively remove residue between and on the surface of the sample comb teeth without damaging the sample comb. The brushes 4 are arranged densely to ensure coverage of all parts of the sample comb, enhancing cleaning effectiveness.

[0028] In the actual operation of this utility model, the user first adds an appropriate amount of cleaning solution to the cleaning tank 1. The cleaning solution can be selected according to the nature of the residue. For example, for acrylamide solution residue, a solution containing a certain concentration of alcohol or a special detergent can be used. Then, the fixing cover 2 is tightly connected to the cleaning tank 1 to prevent the cleaning solution from flowing out and to ensure the smooth progress of the cleaning process. Next, the user vertically inserts the WB sample comb into the sample comb cleaning slot 3 to contact the brush 4, and manually pulls the WB sample comb repeatedly. During the pulling process, the brush 4 in the cleaning tank 1 rubs and cleans the teeth and tooth surfaces of the sample comb, achieving the purpose of thorough cleaning. The above actual operation process does not require complicated operating steps or professional skills. Compared with traditional manual brushing, it greatly saves operating time and effort and improves cleaning efficiency.

[0029] In summary, the traditional method of simply rinsing the comb surface under running water is almost ineffective for firmly adhered gel residues, incompletely polymerized acrylamide solution, and other experimental residues within the narrow gaps between the teeth. The WB sample comb cleaning device provided by this invention, during WB sample comb cleaning, involves vertically inserting the sample comb into the sample comb cleaning slot 3 and repeatedly pulling it out. The brush 4 can penetrate deep into each gap and surface of the WB sample comb, thoroughly removing residues through friction. This effectively avoids the problem of residue clogging the sample loading holes, ensuring the quality of subsequent gel preparation and reducing experimental errors.

[0030] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A cleaning device for a WB sample comb, characterized in that, The device includes a cleaning tank, the top of which is fitted with a fixed cover. A cleaning slit for the WB sample comb teeth is provided through the fixed cover. A brush is provided inside the cleaning tank, located below the cleaning slit of the sample comb.

2. The cleaning device for the WB sample comb according to claim 1, characterized in that, The cleaning tank has a hollow cuboid structure, and the fixing cover has a rectangular plate structure. The fixing cover is detachably connected to the top opening of the cleaning tank.

3. The cleaning device for the WB sample comb according to claim 2, characterized in that, The sample comb cleaning slit is set along the length of the fixed cover and is located in the middle of the fixed cover. The brush is located directly below the sample comb cleaning slit and is set along the length of the cleaning trough. The length covered by the brush is greater than the length of the sample comb cleaning slit.

4. The cleaning device for the WB sample comb according to claim 3, characterized in that, The number of brushes is two, and the two brushes are symmetrically arranged on the two inner walls of the cleaning tank in the width direction. The cleaning bristles of the two brushes are horizontally arranged, and the distance between the ends of the cleaning bristles of the two brushes is 0.1mm.

5. The cleaning device for the WB sample comb according to claim 4, characterized in that, The diameter of the cleaning bristles in each of the brushes is smaller than the spacing between the teeth of the WB sample comb.

6. The cleaning device for the WB sample comb according to claim 5, characterized in that, The vertical distance between the brush and the sample comb cleaning seam is 1mm to 3mm.

7. The cleaning device for the WB sample comb according to claim 2, characterized in that, The top opening of the cleaning tank is provided with a slot, and the four edges of the fixed cover are provided with buckles. The fixed cover and the cleaning tank can be detachably connected by the cooperation of the buckles and the slot.

Images