Multi-liquid preparation machine

Abstract

This utility model discloses a multi-component stock solution preparation machine, including a machine body. A mixing platform is provided on the front side of the machine body, and a settling tank is formed on the mixing platform. An oscillator and a mixing container placed on the settling tank are installed inside the settling tank. Multiple loading slots are provided on the top of the machine body, and a loading platform is detachably installed in each loading slot. A placement cavity is provided inside the machine body, and the placement cavity contains the same number of peristaltic pumps as the loading slots. The input end of each peristaltic pump extends into the loading slot via a connecting pipe, and the output end of each peristaltic pump is connected to a conveying pipe via a multi-port connector. The conveying pipe extends above the mixing platform. This technical solution achieves automated proportioning and mixing of multiple stock solutions, reducing manual intervention; the oscillator embedded in the settling tank ensures stable vibration of the mixing container, improving the uniformity of stock solution mixing; the detachable loading platform design facilitates the replacement of stock solution containers, improving equipment flexibility and maintenance convenience.

Description

Technical Field

[0001] This utility model belongs to the technical field of raw material mixing equipment, and in particular relates to a multi-component raw material mixing machine. Background Technology

[0002] In the fields of chemical engineering, biopharmaceuticals, and fine chemicals, the precise proportioning and uniform mixing of multiple stock solutions are crucial for ensuring product quality. For example, cryopreservation solutions used in cell cryopreservation require preparation using multiple stock solutions.

[0003] Traditional manual mixing methods suffer from low efficiency and high error rates. While existing automated equipment achieves initial automation through components such as peristaltic pumps and metering valves, it still faces the following technical bottlenecks:

[0004] Conventional stirring or static mixing is insufficient to eliminate the separation of the original liquid, especially for multi-component systems with large viscosity differences, making it difficult to balance mixing efficiency and uniformity. Although some equipment incorporates oscillators, it lacks a stable fixing mechanism for the mixing container, and high-frequency vibration can easily cause the container to shift or tip over, affecting the mixing effect.

[0005] Existing loading devices mostly use a fixed structure, making it difficult to adapt to different sizes of raw liquid containers. During puncture sealing, leakage is easily caused by positioning deviation, and the container replacement process is cumbersome, affecting the continuous operation capability of the equipment.

[0006] Traditional equipment lacks modular design, with the platform and conveying system fixedly connected, making maintenance difficult and hindering the rapid switching between different proportion schemes. Summary of the Invention

[0007] The purpose of this invention is to address the problems existing in the prior art by providing a multi-component preparation machine.

[0008] To achieve the above objectives, the utility model adopts the following technical solution: a multi-component stock solution preparation machine, including the machine body, a mixing platform provided on the front side of the machine body, a sinking trough provided on the mixing platform, an oscillator and a mixing container placed thereon installed inside the sinking trough; multiple loading slots provided on the top of the machine body, a loading platform detachably installed in the loading slot; a placement cavity provided inside the machine body, the placement cavity containing the same number of peristaltic pumps as the loading slots, the input end of each peristaltic pump extending into the loading slot through a connecting pipe, and the output end of each peristaltic pump connected to a conveying pipe through a multi-port pipe connector; the conveying pipe extends above the mixing platform.

[0009] In the above technical solution, the integrated mixing platform, multi-loading tank and peristaltic pump linkage system realize the automated proportioning and mixing of various raw liquids, reducing manual intervention; the oscillator embedded in the settling tank ensures stable vibration of the mixing container and improves the uniformity of raw liquid mixing; the detachable platform design facilitates the replacement of raw liquid containers, improving equipment flexibility and maintenance convenience.

[0010] Optionally, the oscillation platform of the oscillator is provided with the tray, and the tray is provided with two opposing high-position clamps, the height of which exceeds the height of the tray; the side wall of the tray is provided with the slide groove, and the side wall of the high-position clamp is provided with the slider extending into the slide groove. The other end of the slider is connected to the knob block through the screw, and the knob block abuts against the outside of the tray to fix the high-position clamp.

[0011] In the above technical solution, the height of the high-position clamping plate exceeds the height of the tray. Through the cooperation of the slider, screw, and knob block, it can stably clamp mixing containers of different sizes, preventing them from shaking, shifting, or tipping over during oscillation. This ensures the stability of the mixing process and the uniformity of the mixing effect, avoiding problems such as spillage of the original liquid or uneven mixing due to container instability. The high-position clamping plate can slide within the tray and be fixed by the knob block. The position of the clamping plate can be flexibly adjusted according to the actual size of the mixing container, adapting to various specifications of mixing containers and enhancing the versatility and applicability of the equipment.

[0012] Optionally, the feed pipe is inclined downwards from the placement chamber towards the mixing platform, with its end directly above the center of the oscillator. This downward inclination utilizes gravity to allow the concentrate to flow smoothly from the peristaltic pump output to the mixing platform, preventing accumulation and air resistance in the feed pipe. This ensures the stability and continuity of concentrate delivery, improving the efficiency and accuracy of concentrate preparation. The end of the feed pipe being directly above the center of the oscillator ensures accurate dripping of the concentrate into the mixing container, preventing waste and contamination from dripping onto the container's outer wall or other parts. It also facilitates subsequent mixing operations, ensuring the concentrate is thoroughly and evenly mixed with other concentrates in a timely manner.

[0013] Optionally, the conveying pipe is a plastic pipe, which is inclined downward from the placement cavity towards the mixing platform. The inclination angle of the conveying pipe is 10°-30°, and the end is bent and kept in a fixed shape.

[0014] In the above technical solution, the conveying pipe uses a flexible conduit that can be bent freely and maintain its fixed shape after bending. This allows operators to easily adjust the direction and position of the conveying pipe according to actual work needs, making it better adaptable to different operating spaces and layouts. It also facilitates the installation, commissioning, and maintenance of the equipment. By specifying the inclination angle of the conveying pipe as 10°-30°, within this range, the smooth delivery of the raw liquid is ensured without making the conveying pipe too steep, thus avoiding excessive space occupation or causing the raw liquid flow rate to be too fast and difficult to control. This helps to optimize the structural design and working performance of the equipment.

[0015] Optionally, the top surface of the platform is an inclined surface that slopes downward toward the mixing platform, and the inclined surface has a placement groove. The bottom wall of the placement groove has a positioning groove, and a puncture needle is installed on the bottom wall of the positioning groove.

[0016] In the above technical solution, the top surface of the stage is an inclined plane sloping downwards towards the mixing platform. The placement groove facilitates the placement of the raw liquid container, and the inclined design helps guide the raw liquid container into the placement groove, allowing it to be placed more stably on the stage and preventing it from rolling or shaking, thus improving the safety and convenience of operation. The positioning groove is adapted to the bottleneck of the raw liquid container, enabling precise positioning of the container and ensuring that the puncture needle can accurately pierce the rubber seal of the container, allowing the raw liquid to flow out smoothly. At the same time, the positioning groove provides a certain degree of fixation for the container, ensuring the stability of the puncture process and avoiding the risk of puncture failure or raw liquid leakage.

[0017] Optionally, when the loading platform is inserted into the loading slot, the connecting pipe and the docking slot are plugged in to ensure that the connecting pipe and the docking slot at the bottom of the puncture needle are tightly connected, ensuring the sealing of the raw liquid transportation and preventing leakage of the raw liquid during transportation. At the same time, it also improves the accuracy and stability of docking, so that the raw liquid can be smoothly transported from the raw liquid container to the delivery pipe through the connecting pipe.

[0018] Optionally, the puncture needle is a hollow tube needle, and the bottom wall of the stage is provided with a docking groove that connects with the puncture needle. The puncture needle is a hollow tube needle, and its internal channel allows the raw liquid to flow smoothly out of the raw liquid container. The puncture needle is installed on the bottom wall of the positioning groove. When the raw liquid container is accurately positioned, the puncture needle can accurately penetrate the rubber seal, ensuring the efficiency and stability of the raw liquid outflow and providing a reliable inlet channel for the delivery of hollow liquid.

[0019] Optionally, the shape of the positioning groove is adapted to the bottleneck of the original liquid container.

[0020] Optionally, a hook is provided on one side of the platform to facilitate operators in hanging auxiliary tools or signs on the platform, such as labels for marking the original solution information or straps for securing the original solution container. This allows operators to easily access or view relevant information during the work process, improving operational convenience and work efficiency. It can also be used to directly hang bagged original solutions.

[0021] Optionally, the machine body is integrated with an operation screen for operating the entire machine's operation process.

[0022] Compared with the prior art, the beneficial effects of this utility model are as follows: 1. This multi-component stock solution preparation machine integrates a mixing platform, multiple loading tanks, and a linked peristaltic pump system to achieve automatic proportioning and mixing of multiple stock solutions. The oscillator in the settling tank improves the uniformity of mixing, and the detachable platform facilitates container replacement and maintenance; 2. The inclined surface of the platform and the placement tank guide the stock solution container to a stable position, preventing rolling and improving operational safety; 3. The positioning tank adapts to the container bottleneck, accurately positioning the puncture position of the puncture needle to ensure stable insertion of the sealing port and avoid leakage; 4. When the platform and the loading tank are connected, the connecting pipe and the bottom of the puncture needle are sealed and connected to ensure that the stock solution is delivered without leakage. Attached Figure Description

[0023] Figure 1 A three-dimensional view of the front side of a multi-component preparation machine provided for an embodiment of this utility model;

[0024] Figure 2 A three-dimensional view of the rear structure of a multi-component preparation machine provided for an embodiment of this utility model;

[0025] Figure 3 A three-dimensional perspective view of the rear cross-section of a multi-component preparation machine provided for an embodiment of this utility model;

[0026] Figure 4 This is a three-dimensional view of the stage of this utility model;

[0027] Figure 5 This is a three-dimensional view of the cross-section of the stage of this utility model.

[0028] In the diagram: 1. Machine body; 2. Mixing platform; 21. Settling tank; 3. Vibrator; 4. Mixing container; 5. Loading tank; 51. Connecting pipe; 6. Platform; 61. Placement tank; 62. Positioning tank; 63. Puncture needle; 64. Connecting tank; 65. Hook; 7. Placement cavity; 8. Peristaltic pump; 9. Feeding pipe; 10. Control panel. Detailed Implementation

[0029] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0030] In the description of this utility model, it should be noted that the terms "middle", "upper", "lower", "left", "right", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0031] like Figure 1-3 As shown, the specific solution of the embodiment is as follows: A multi-component stock solution preparation machine includes a machine body 1, a mixing platform 2 is provided on the front side of the machine body 1, a settling tank 21 is provided on the mixing platform 2, and an oscillator 3 is installed inside the settling tank 21 for uniformly mixing the proportioned stock solutions together. A mixing container 4 is placed on the oscillator 3. The oscillator 3 can be a commercially available vortex oscillator 3 or a commercially available shaking table oscillator 3.

[0032] It is important to note that in this embodiment, the oscillation platform of the oscillator 3 is equipped with a dedicated tray. Inside the tray are two opposing high-position clamps, the height of which exceeds the height of the tray to ensure stable clamping of the mixing container 4. The two ends of the high-position clamps are flat and meet the inner walls of the tray on both sides to prevent them from shifting when sliding within the tray. A groove is provided on the side of the tray that contacts the high-position clamps. Simultaneously, a slider extending into the groove is provided on one side of the high-position clamps. A screw extending out of the groove is fixed to the other end of the slider, and a knob block with a diameter larger than the groove is threaded onto the other end of the screw. When the knob block presses against the outside of the tray, the high-position clamps are secured. Furthermore, this design, combined with the high-position clamps being taller than the tray, ensures stable and reliable clamping of the mixing container 4, thus solving the problem of the lack of a stable fixing mechanism for the mixing container in existing technologies.

[0033] The high-position clamping plate extends beyond the tray height and, through the cooperation of sliders, screws, and knobs, can stably clamp mixing containers 4 of different sizes. This prevents the containers 4 from shaking, shifting, or tipping over during oscillation, ensuring the stability of the mixing process and the uniformity of the mixing effect. It avoids problems such as spillage of the original liquid or uneven mixing due to container instability. The high-position clamping plate can slide within the tray and be fixed by the knobs. The clamping plate position can be flexibly adjusted according to the actual size of the mixing container 4, adapting to various specifications of mixing containers 4 and enhancing the equipment's versatility and applicability.

[0034] In this embodiment, multiple loading slots 5 are provided on the top of the machine body 1. A platform 6 is detachably installed in the loading slot 5 for loading the raw liquid container. A placement cavity 7 is provided inside the machine body 1, and a peristaltic pump 8 is installed in the placement cavity 7 to transport the raw liquid in the raw liquid container. Multiple peristaltic pumps 8 are configured, and their specific number is the same as the number of loading slots 5. The peristaltic pump 8 corresponds one-to-one with the loading slot 5. The input end of each peristaltic pump 8 is equipped with a connecting pipe 51 extending from the placement cavity 7 into the loading slot 5. The connecting pipe 51 is an aluminum alloy pipe. The output ends of all peristaltic pumps 8 are connected to the same conveying pipe 9 through a multi-port pipe joint. The other end of the conveying pipe 9 extends from the placement cavity 7 to the top of the mixing platform 2.

[0035] In the above technical solution, the integrated mixing platform 2, multi-loading tank 5 and peristaltic pump 8 linkage system realizes the automated proportioning and mixing of various raw liquids, reducing manual intervention; the oscillator 3 embedded in the settling tank 21 ensures stable vibration of the mixing container 4 and improves the uniformity of raw liquid mixing; the detachable platform 6 is designed to facilitate the replacement of raw liquid containers, improving the flexibility of the equipment and the convenience of maintenance.

[0036] It should be noted that the feed pipe 9 is made of a pipe with certain plasticity characteristics, which can maintain its bent state after being bent at will. Secondly, the end of the feed pipe 9 is located at the center of the vibrator 3, which can ensure that the output raw liquid can be accurately dripped into the mixing container 4.

[0037] The feed pipe 9, employing a flexible conduit, can be bent freely and maintain its fixed shape after bending. This allows operators to easily adjust the direction and position of the feed pipe 9 according to actual work needs, making it better adaptable to different operating spaces and layouts. It also facilitates equipment installation, commissioning, and maintenance. By defining the inclination angle of the feed pipe 9 as 10°-30°, this range ensures smooth delivery of the raw liquid without making the feed pipe 9 too steep, thus avoiding excessive space occupation or causing the raw liquid flow rate to be too fast and difficult to control. This helps optimize the structural design and working performance of the equipment.

[0038] Another point to mention is that the conveying pipe 9 is inclined downwards from the placement chamber 7 toward the mixing platform 2, and the inclination angle of the conveying pipe 9 is 10°-30° to ensure that the raw liquid can flow out smoothly from the cooked material pipe.

[0039] like Figure 4-5 As shown, in this embodiment, the top surface of the stage 6 is inclined and tilts downwards towards the mixing platform 2. A downwardly inclined placement groove 61 is provided on the top surface of the stage 6 for placing the stock solution container. A positioning groove 62 is provided on the bottom wall of the placement groove 61 for docking with the neck of the stock solution container. A puncture needle 63 is installed on the bottom wall of the positioning groove 62, which can penetrate the rubber seal at the neck of the stock solution container. The puncture needle 63 is a hollow tube needle; after the puncture needle 63 is inserted into the stock solution container, the stock solution inside the container will flow out from the puncture needle 63. A docking groove 64 penetrating the bottom wall of the stage 6 is provided at the bottom end of the puncture needle 63.

[0040] In this embodiment, the placement groove 61 facilitates the placement of the concentrate container, and the inclined design helps guide the concentrate container into the placement groove 61, allowing it to be placed more stably on the platform 6, preventing it from rolling or shaking on the platform 6, thus improving the safety and convenience of operation. The positioning groove 62 is adapted to the bottleneck of the concentrate container, enabling precise positioning of the concentrate container and ensuring that the puncture needle 63 can accurately pierce the rubber seal of the concentrate container, allowing the concentrate to flow out smoothly. At the same time, the positioning groove 62 provides a certain degree of fixation for the concentrate container, ensuring the stability of the puncture process and avoiding the risk of puncture failure or concentrate leakage. Furthermore, due to the inclined design of the placement groove 61, under the guidance of the inclined surface and the weight of the concentrate container, the concentrate container slides into the positioning groove 62, and the puncture needle 63 on the bottom wall of the positioning groove 62 pierces the rubber seal of the concentrate container, enabling automatic puncture of the bottle stopper or bag opening of the concentrate packaging without manual intervention.

[0041] In this embodiment, when the platform 6 is inserted into the loading slot 5, the connecting pipe 51 is aligned and inserted into the docking slot 64. This ensures that the connecting pipe 51 is tightly connected to the docking slot 64 at the bottom of the puncture needle 63, ensuring the sealing of the raw liquid transportation and preventing leakage of the raw liquid during transportation. It also improves the accuracy and stability of docking, allowing the raw liquid to be smoothly transported from the raw liquid container to the conveying pipe 9 through the connecting pipe 51.

[0042] It should be noted that, in this embodiment, the placement slot 61 on the stage 6 can be designed in various sizes to accommodate different specifications of raw liquid containers.

[0043] A hook 65 is provided on one side of the platform 6, which makes it convenient for operators to hang some auxiliary tools or signs on the platform 6, such as labels for marking the original liquid information, straps for fixing the original liquid container, etc., so that operators can easily access or view relevant information during the work process, improving the convenience of operation and work efficiency. It can also be used to hang bagged original liquid.

[0044] Finally, an operation screen 10 is also installed on the machine body 1. The operation screen 10 integrates the existing proportioning system for the peristaltic pump 8 to accurately deliver each original liquid.

[0045] The workflow of the above embodiments is as follows:

[0046] 1. Preparation

[0047] (1) Check the equipment: Ensure that the stage 6, peristaltic pump 8, mixing container 4 and shaker are intact and correctly installed.

[0048] (2) Prepare raw materials and ingredients: Prepare the various raw materials that need to be configured according to production needs, and ensure that the packaging form of the raw materials is compatible with the platform 6.

[0049] (3) Select mixing container 4: Select a suitable mixing container 4 according to the capacity of the original agent and the mixing requirements.

[0050] 2. Installation and Setup

[0051] (1) Install the platform 6: Install the detachable platform 6 onto the equipment to ensure that the bottle stopper puncturer can work properly.

[0052] (2) Connect the infusion set: Connect the standardized infusion set to the puncture device, peristaltic pump 8 and mixing container 4, ensuring that the connection is well sealed to avoid leakage.

[0053] (3) Set up peristaltic pump 8: Set the delivery rate and speed of peristaltic pump 8 according to the mixing ratio requirements of the raw material. Ensure that the parameters of peristaltic pump 8 in each channel are set correctly to achieve accurate mixing ratio.

[0054] (4) Install the mixing container 4: Place the selected mixing container 4 on the tray of the oscillator 3 and fix it with the high-position clamp to ensure that the container will not shift or tip over during the oscillation process.

[0055] 3. Configuration process

[0056] (1) Initiating bottle stopper puncture: Place the concentrate container into the placement slot 61 of the stage 6. Guided by the inclined plane and under its own weight, the concentrate container slides into the positioning slot 62. The puncture needle 63 on the bottom wall of the positioning slot 62 punctures the rubber seal of the concentrate container. The concentrate flows into the peristaltic pump 8 through the hollow puncture needle 63, the docking slot 64, and the docking pipe 51. This achieves automatic puncture of the bottle stopper or bag opening of the concentrate packaging without manual intervention.

[0057] (2) Start delivery of raw materials: Start the peristaltic pump 8 and begin to deliver multiple raw materials to the mixing container 4 through the infusion set according to the preset delivery volume and speed. Ensure that the delivery process of each raw material is smooth and accurate.

[0058] (3) Shaking and mixing: After all the raw materials are delivered to the mixing container 4, start the shaker 3. Set the frequency, amplitude and time of the shaking according to the mixing requirements to ensure that the raw materials can be mixed efficiently and uniformly.

[0059] (4) Monitoring process: During the configuration process, monitor the operating status of the equipment in real time to ensure that all components are working properly. If any abnormality occurs, stop the machine and check it immediately.

[0060] 4. End and cleanup

[0061] (1) Stop the equipment: After mixing is complete, stop the oscillator 3 and the peristaltic pump 8, and turn off the power to the equipment.

[0062] (2) Disassemble mixing container 4: Remove mixing container 4 from oscillator 3 and take out the prepared compound.

[0063] (3) Cleaning and maintenance: Disassemble the platform 6, infusion set and mixing container 4, and clean them thoroughly to ensure no residue remains. Regularly maintain the equipment, check the working status of each component, and ensure that the equipment is in optimal condition for the next use.

[0064] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A multiple stock solution preparation machine comprising a machine body, characterized by, The machine body has a mixing platform on its front side, and a sinking trough is formed on the mixing platform. A vibrator and a mixing container placed on the sinking trough are installed inside the sinking trough. The top of the machine body has multiple loading slots, and a loading platform can be detachably installed in each loading slot. The machine body has a placement cavity, and the placement cavity contains the same number of peristaltic pumps as the loading slots. The input end of each peristaltic pump extends into the loading slot through a connecting pipe, and the output end of each peristaltic pump is connected to a conveying pipe through a multi-port pipe connector. The conveying pipe extends above the mixing platform. The oscillator's oscillation platform is provided with a tray, and the tray contains two opposing high-position clamps, the height of which exceeds the height of the tray. The side wall of the tray is provided with a sliding groove, and the side wall of the high-position clamps is provided with a slider extending into the sliding groove. The other end of the slider is connected to a knob block via a screw, and the knob block abuts against the outside of the tray to fix the high-position clamps.

2. The multiple stock solution preparation machine according to claim 1, wherein The feed pipe is inclined downward from the placement chamber toward the mixing platform, and the end of the feed pipe is located directly above the center of the oscillator.

3. The multiple stock solution preparation machine of claim 2, wherein, The conveying pipe is a plastic pipe, which is inclined downward from the placement cavity towards the mixing platform. The inclination angle of the conveying pipe is 10°-30°, and the end is bent and maintains a fixed shape.

4. The multiple stock solution preparation machine of claim 1, wherein The top surface of the platform is an inclined plane that slopes downward toward the mixing platform. A placement groove is provided on the inclined plane. A positioning groove is provided on the bottom wall of the placement groove. A puncture needle is installed on the bottom wall of the positioning groove.

5. The multiple stock solution preparation machine of claim 4, wherein, The puncture needle is a hollow tube needle, and the bottom wall of the stage has a docking groove that connects with the puncture needle.

6. The multiple stock solution preparation machine of claim 4, wherein, The shape of the positioning groove is adapted to the bottleneck of the original liquid container.

7. The multiple stock solution preparation machine of claim 4, wherein, A hook is provided on one side of the platform.

8. The multiple stock solution preparation machine of claim 1, wherein, The machine body is equipped with an operation screen.

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